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| Product | Description | |
|---|---|---|
| L-Alaninamide | Synonyms: H-Ala-NH2. CAS No. 7324-5-2. Molecular formula: C3H8N2O. Mole weight: 88.1. |  |
| L-Alaninamide HCl | L-Alaninamide HCl. Group: Biochemicals. Grades: Highly Purified. CAS No. 33208-99-0. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences. |  Worldwide |
| L-Alaninamide,N-(ethoxycarbonyl)-L-alanyl-L-tyrosyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]-(9ci) | L-Alaninamide,N-(ethoxycarbonyl)-L-alanyl-L-tyrosyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]-(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: ETHOXYCARBONYL-ALA-TYR-VAL-ALA-ASP-ALDEHYDE (PSEUDO ACID). Product Category: Heterocyclic Organic Compound. CAS No. 160534-05-4. Molecular formula: C27H39N5O10. Mole weight: 593.63. Purity: 0.96. IUPACName: (3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-(ethoxycarbonylamino)propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-4-oxobutanoicacid. Canonical SMILES: CCOC(=O)NC(C)C(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NC(CC(=O)O)C=O. Product ID: ACM160534054. Alfa Chemistry ISO 9001:2015 Certified. |  |
| N-[2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide Acetic Acid | N-[2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide Acetic Acid. Group: Biochemicals. Alternative Names: TAPI-2 Acetic Acid. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C21H41N5O7, Molecular Weight: 475.58. US Biological Life Sciences. | Worldwide |
| N?-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide | for chiral derivatization, ?99.0%. Group: Chiral derivatization reagents. |  |
| N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide | TAPI 2 is an ADAM-17 (TACE) and matrix metalloprotease (MMP) inhibitor (Ki = 120 nM at ADAM-17). TAPI 2 sensitizes cancer stem cells to the lethal effects of 5-FU in vitro, and inhibits shedding of TNF-α from cell membranes. Synonyms: TAPI 2; TAPI2; TAPI-2; N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide; Immunex compound 1. Grades: ≥95% by HPLC. CAS No. 689284-12-6. Molecular formula: C19H37N5O5. Mole weight: 415.54. | |
| N-[ (Phenylmethoxy) carbonyl]-L-valyl-N-[3-fluoro-1- (2-methoxy-2-oxoethyl) -2-oxopropyl]-L-alaninamide | N-[ (Phenylmethoxy) carbonyl]-L-valyl-N-[3-fluoro-1- (2-methoxy-2-oxoethyl) -2-oxopropyl]-L-alaninamide. Group: Biochemicals. Alternative Names: Z-VAD-FMK; Benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone. Grades: Highly Purified. CAS No. 634911-81-2. Pack Sizes: 1 mg. Molecular Formula: C22H30FN3O7, Molecular Weight: 467.49. US Biological Life Sciences. | Worldwide |
| AAF-CMK trifluoroacetate salt | AAF-CMK is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome function, and reversibly inhibits Cln2 (TPPI). Synonyms: N-Ala-Ala-Phe-CMK; Tripeptidyl Peptidase Inhibitor II; L-Alaninamide,L-alanyl-N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-. Grades: ≥95%. CAS No. 184901-82-4. Molecular formula: C18H23ClF3N3O5. Mole weight: 453.84. | |
| Acetyl Pepstatin | Acetyl Pepstatin is a high affinity HIV-1 protease inhibitor and aspartic protease inhibitor. It inhibits HIV-1 protease with Ki value of 20 nM at pH 4.7 and HIV-2 protease with Ki value of 5 nM at pH 4.7. It is used as an antiviral agent. Synonyms: Ac-Pepstatin; [1S-[1R*,2R*,4[R*[R*(R*)]]]]-1-(2-Methylpropyl)-4-oxobutyl]-N-acetyl-L-valyl-N-[4-[[2-[[1-(2-carboxy-1-hydroxyethyl)-3-methylbutyl]amino]-1-methyl-2-oxoethyl]amino]-2-hydroxy-L-valinamide; Pepsin Inhibitor S-PI-D (8CI); N-Acetyl-L-valyl-L-valyl-(3S,4S)-4-amino-3-hydroxy-6- methylheptanoyl-N-[(1S)-1-[(1S)-2-carboxy-1-hydroxyethyl]-3-methylbutyl]-L-alaninamide; Pepsidin C; S-PI; (4S,7S,8S,10S,19S)-8-carbamoyl-11,19-dihydroxy-10,18-diisobutyl-4-isopropyl-7,15-dimethyl-2,5,13,16-tetraoxo-3,9,14,17-tetraazahenicosan-21-oic acid. Grades: >98%. CAS No. 11076-29-2. Molecular formula: C31H57N5O9. Mole weight: 643.81. | |
| Ac-Val-Asp-Val-Ala-Asp-aldehyde (pseudo acid) | Ac-VDVAD-CHO is an inhibitor of caspase-2, -3, and -7 (Kis = 3.5, 1, and 7.5 nM, respectively). Synonyms: Ac-VDVAD-CHO; N-acetyl-L-valyl-L-alpha-aspartyl-L-valyl-L-alanyl-L-aspart-1-al; N-Acetyl-L-valyl-L-α-aspartyl-L-valyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-alaninamide; L-Alaninamide, N-acetyl-L-valyl-L-α-aspartyl-L-valyl-N-[(1S)-2-carboxy-1-formylethyl]-; Caspase-2 Inhibitor (Aldehyde). Grades: ≥95%. CAS No. 194022-51-0. Molecular formula: C23H37N5O10. Mole weight: 543.57. | |
| Ac-WLA-AMC | Ac-WLA-AMC is a fluorogenic substrate for the β5c subunit of the 20S proteasome. Ac-WLA-AMC is cleaved to release the fluorescent moiety 7-amino-4-methylcoumarin (AMC), which can be used to quantify the β5c subunit activity. Synonyms: Acetyl-Trp-Leu-Ala-7-amino-4-Methylcoumarin; N-acetyl-L-tryptophyl-L-leucyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-alaninamide. Grades: ≥95%. CAS No. 1104011-59-7. Molecular formula: C32H37N5O6. Mole weight: 587.7. | |
| Ac-YVAD-CHO | Ac-YVAD-CHO is a selective inhibitor of interleukin-1β converting enzyme (ICE; Caspase-1). Uses: Cysteine proteinase inhibitors. Synonyms: Acetyl-tyrosyl-valyl-alanyl-aspartal; Ac-Tyr-Val-Ala-Asp-H; N-acetyl-Tyr-Val-Ala-Asp-aldehyde; (S)-N-Acetyl-L-tyrosyl-L-valyl-N-(2-carboxy-1-formylethyl)-L-alaninamide. Grades: ≥98%. CAS No. 143313-51-3. Molecular formula: C23H32N4O8. Mole weight: 492.52. | |
| Alanine-nh2 acetate salt | Alanine-nh2 acetate salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-ALANINE AMIDE ACETATE; H-Ala-NH2; H-Ala-NH2(L-Alaninamide); H-ALA-NH2 ACOH; L-ALANINE AMIDE ACETATE SALT; H-ALA-NH2 ACETATE SALT. Product Category: Heterocyclic Organic Compound. CAS No. 119864-22-1. Molecular formula: C3H8N2O. Mole weight: 88.11. Purity: 0.96. IUPACName: acetic acid;2-aminopropanamide. Canonical SMILES: CC(C(=O)N)N.CC(=O)O. Product ID: ACM119864221. Alfa Chemistry ISO 9001:2015 Certified. | |
| Alanylbactobolin | It is produced by the strain of Pseudomonas sp. BMG 13-A7. It has anti-gram-positive bacteria, negative bacteria and tumor activity. Synonyms: Bactobolin B; L-Alaninamide, L-alanyl-N-(3-(dichloromethyl)-3,4,4a,5,6,7-hexahydro-5,6,8-trihydroxy-3-methyl-1-oxo-1H-2-benzopyran-4-yl)-, (3S-(3-alpha,4-alpha,4a-beta,5-beta,6-alpha))-; DTXSID80995581; 5-Amino-2-{[3-(dichloromethyl)-1,5,6-trihydroxy-3-methyl-8-oxo-4,4a,5,6,7,8-hexahydro-3H-2-benzopyran-4-yl]amino}-4-oxohexanimidic acid. CAS No. 74141-68-7. Molecular formula: C17H25N3O7Cl2. Mole weight: 454.30. | |
| Alatrofloxacin Mesylate | Alatrofloxacin Mesylate is the mesylate salt form of the fluoroquinolone derivative Alatrofloxacin, a type II DNA topoisomerase inhibitor that has been developed as an antibacterial agent. Synonyms: L-Alaninamide, L-alanyl-N-[(1α,5α,6α)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-, methanesulfonate (1:1); L-Alaninamide, L-alanyl-N-[(1α,5α,6α)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-, monomethanesulfonate; L-Alaninamide, L-alanyl-N-[3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-, (1α,5α,6α)-, monomethanesulfonate; Adrenochrome monoaminoguanidine mesilate; CP 116517; CP 116517-27; Trovan IV; Turvel IV; 7-((1R,5S,6s)-6-((S)-2-((S)-2-aminopropanamido)propanamido)-3-azabicyclo[3.1.0]hexan-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid compound with methanesulfonic acid (1:1). Grades: ≥95%. CAS No. 146961-77-5. Molecular formula: C27H29F3N6O8S. Mole weight: 654.61. | |
| Alatrofloxacin Mesylate | Alatrofloxacin Mesylate. Uses: For analytical and research use. Group: Chiral molecules. Alternative Names: 3-Azabicyclo[3.1.0]hexane, L-alaninamide deriv., CP 116517, L-Alaninamide, L-alanyl-N-[3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-, (1?,5?,6?)-, monomethanesulfonate, CP 116517-27, L-Alaninamide, L-alanyl-N-[(1?,5?,6?)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-, monomethanesulfonate (9CI), Adrenochrome monoaminoguanidine mesilate, Alatrofloxacin mesylate,Alatrofloxacin Mesylate, L-Alaninamide, L-alanyl-N-[(1?,5?,6?)-3-[6-carboxy-8-(2,4-difluorophenyl)-3-fluoro-5,8-dihydro-5-oxo-1,8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-, methanesulfonate (1:1). CAS No. 146961-77-5. IUPAC Name: 7-[(1R,5S)-6-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]propanoyl]amino]-3-azabicyclo[3.1.0]hexan-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;methanesulfonic acid. Molecular formula: C26H25F3N6O5.CH4O3S. Mole weight: 654.61. Catalog: APS146961775. SMILES: C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@H]1[C@@H]2CN(C[C@H]12)c3nc4N(C=C(C(=O)O)C(=O)c4cc3F)c5ccc(F)cc5F.CS(=O)(=O)O. Format: Neat. | |
| Alatrofloxacin Mesylate | The parental prodrug of Trovafloxacin, on phagocytic, anti-inflammatory and immunomodulation events of human THP-1 monocytes. Group: Biochemicals. Alternative Names: L-Alanyl-N-[(1α, 5α, 6α)-3-[6-carboxy-8-(2, 4-difluorophenyl)-3-fluoro-5, 8-dihydro-5-oxo-1, 8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-L-alaninamide Methanesulfonate; L-Alanyl-N-[(1α, 5α, 6α)-3-[6-carboxy-8-(2, 4-difluorophenyl)-3-fluoro-5, 8-dihydro-5-oxo-1, 8-naphthyridin-2-yl]-3-azabicyclo[3.1.0]hex-6-yl]-L-alaninamide Mesylate. Grades: Highly Purified. CAS No. 146961-77-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| α-helical CRF 9-41 | α-helical CRF 9-41 has been found to be a corticotropin-releasing factor receptor antagonist. Synonyms: Corticotropin-releasing factor (human), 1-de-L-serine-2-de-L-glutamicacid-3-de-L-glutamicacid-4-de-L-proline-5-de-L-proline-6-de-L-isoleucine-7-de-L-serine-8-de-L-leucine-18-L-methionine-23-L-lysine-27-L-glutamic acid-29-L-glutamicacid-32-L-alanine-33-L-leucine-36-L-leucine-38-L-leucine-40-L-glutamicacid-41-L-alaninamide-; CHEMBL526149. Grades: ≥95% by HPLC. CAS No. 90880-23-2. Molecular formula: C166H274N46O53S2. Mole weight: 3827.00. | |
| α-Synuclein Binding Peptide | α-Synuclein Binding Peptide is a 10-residue peptide antagonist, corresponding to the sequence of the α-synuclein binding peptide, and effectively inhibits α-synuclein aggregation and related toxicity at 1:1 stoichiometry. Synonyms: L-Alaninamide, N2-acetyl-L-lysyl-L-α-aspartylglycyl-L-isoleucyl-L-valyl-L-asparaginylglycyl-L-valyl-L-lysyl-; Ac-Lys-Asp-Gly-Ile-Val-Asn-Gly-Val-Lys-Ala-NH2; α-syn Binding Peptide. Grades: ≥95%. CAS No. 2243207-00-1. Molecular formula: C45H80N14O14. Mole weight: 1041.20. | |
| Boc-Ala-NH2 | Boc-Ala-NH2 (CAS# 85642-13-3) is a useful research chemical. Synonyms: N-α-(t-Butoxycarbonyl)-L-alaninamide; (S)-tert-Butyl (1-amino-1-oxopropan-2-yl)carbamate; (S)-Boc-alaninamide. CAS No. 85642-13-3. Molecular formula: C8H16N2O3. Mole weight: 188.23. | |
| Chitinovorin B | Chitinovorin B is produced by the strain of Flavobacerium chitinovorum PB-5016 and PB-5246. Synonyms: L-Alaninamide, L-alanyl-N-(4-((7-((5-amino-5-carboxy-1-oxopentyl)amino)-2-carboxy-7-(formylamino)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methoxy)-1-(3-((aminoiminomethyl)amino)propyl)-2-hydroxy-4-oxobutyl)-, (6R-(3(1S*,2R*),6alpha,7beta(R*)))-. Grades: >98%. CAS No. 95722-76-2. Molecular formula: C29H46N10O12S. Mole weight: 758.80. | |
| CI 992 | CI 992 is a renin inhibitor originated by Pfizer. Preclinical trials for Hypertension in USA was discontinued in 1994. Uses: Hypertension. Synonyms: CI 992; CI992; CI-992. N-(4-morpholinylsulfonyl)-L-phenylalanyl-3-(2-amino-4-thiazolyl)-N-[(1S,2R,3S)-1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-alaninamide; [1S-(1R*,2S*,3R*)]- N-(4-morpholinylsulfonyl)-L-phenylalanyl-3-(2-amino-4-thiazolyl)-N-[1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl]-L-alaninamide; PD 134672; PD134672; PD-134672. Grades: 98%. CAS No. 135704-06-2. Molecular formula: C33H52N6O7S2. Mole weight: 708.94. | |
| Compound E | Compound E is a cell-permeable inhibitor of γ-secretase (GSI), which is a multifunctional transmembrane protein complex enzymatically catalyzing the cleavage of single-pass transmembrane proteins. Compound E can inhibit Notch processing (IC50 = 2.2 nM in SupT1 cells) and β-ammyloid production in cell culture (IC50 = 0.3 nM). Synonyms: γ-Secretase Inhibitor; Gamma-Secretase Inhibitor XXI; (S,S)- 2-[2-(3,5-Difluorophenyl)-acetylamino]-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionamide; (2S)-2-{[(3,5-Difluorophenyl)acetyl]amino}-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide; N2-[(3,5-difluorophenyl)acetyl]-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-L-alaninamide. Grades: 99%. CAS No. 209986-17-4. Molecular formula: C27H24F2N4O3. Mole weight: 490.5. | |
| FE-999024 | FE-999024, a dipeptide compound, has been found to be a kallikrein inhibitor that was once studied in pancreatitis by Ferring Pharmaceuticals. Synonyms: FE-999024; FE 999024; FE999024; CH-2856; CH2856; CH 2856; L-Alaninamide, 4-chloro-D-phenylalanyl-N-(3-((aminoiminomethyl)amino)propyl)-3-(1-naphthalenyl)-. Grades: 98%. CAS No. 168825-65-8. Molecular formula: C26H31ClN6O2. Mole weight: 495.02. | |
| FK 888 | FK 888 is a potent and selective tachykinin NK1 receptor antagonist (Ki = 0.69 nM) with 320-fold selectivity for human over rat NK1 receptors. It inhibits substance P-induced contraction of isolated guinea pig trachea (IC50 = 32 nM) and inhibits substance P-induced airway constriction in vivo following i.v. and oral administration. Synonyms: FK-888; FK 888; FK888. (4R)-4-Hydroxy-1-[(1-methyl-1H-indol-3-yl)carbonyl]-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-L-alaninamide; (2S,4R)-N-[(2S)-1-[benzyl(methyl)amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-4-hydroxy-1-(1-methylindole-3-carbonyl)pyrrolidine-2-carboxamide. Grades: ≥98% by HPLC. CAS No. 138449-07-7. Molecular formula: C36H36N4O4. Mole weight: 588.69. | |
| Fluorescein-6-carbonyl-Tyr-Val-Ala-DL-Asp(OMe)-fluoromethylketone | Fluorescein-6-carbonyl-Tyr-Val-Ala-DL-Asp(OMe)-fluoromethylketone is an inhibitor of caspase-1. Synonyms: 6-FAM-YVAD(OMe)-FMK; L-Alaninamide, N-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-6-yl)carbonyl]-L-tyrosyl-L-valyl-N-[1-(2-fluoroacetyl)-3-methoxy-3-oxopropyl]-; N-[(3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-6-yl)carbonyl]-L-tyrosyl-L-valyl-N-(5-fluoro-1-methoxy-1,4-dioxo-3-pentanyl)-L-alaninamide. Grades: ≥90%. CAS No. 1926163-69-0. Molecular formula: C44H43FN4O13. Mole weight: 854.84. | |
| Fluorogenic Human CMV Protease Substrate | Fluorogenic Human CMV Protease Substrate, the FRET substrate, is used to develop a fluorescence-based detection method for human cytomegalovirus proteinase. It specifically cleaves on the Ala-Ser bond, thereby removing the C-terminal peptide-Edans fragment from the proximity quenching effect of DABCYL groups. This represents the first fluorescence-based assay of the herpes virus protease and allows characterization of potential inhibitors. Synonyms: DABCYL-Arg-Gly-Val-Val-Asn-Ala-Ser-Ser-Arg-Leu-Ala-EDANS; N2-[4-[2-[4- (Dimethylamino) phenyl]diazenyl]benzoyl]-L-arginylglycyl-L-valyl-L-valyl-L-asparaginyl-L-alanyl-L-seryl-L-seryl-L-arginyl-L-leucyl-N-[2-[ (5-sulfo-1-naphthalenyl) amino]ethyl]-L-alaninamide. Grades: 95%. CAS No. 163265-38-1. Molecular formula: C73H109N23O18S. Mole weight: 1628.85. | |
| H-Ala-Ala-pNA | H-Ala-Ala-pNA is a substrate for dipeptidyl peptidase V (DPPV) from Aspergillus fumigatus. Synonyms: L-Alanyl-L-alanine 4-nitroanilide; L-Alaninamide, L-alanyl-N-(4-nitrophenyl)-. CAS No. 57282-69-6. Molecular formula: C12H16N4O4. Mole weight: 280.28. | |
| H-Lys-Ala-pNA 2HCl | H-Lys-Ala-pNA 2HCl, a chromogenic substrate for dipeptidyl aminopeptidase II (DPPII), is cleaved from Aspergillus fumigatus by dipeptidyl peptidase V (DPP V). Synonyms: KA-pNA dihydrochloride; L-Lysyl-N-(4-nitrophenyl)-L-alaninamide dihydrochloride; L-Alaninamide, L-lysyl-N-(4-nitrophenyl)-, hydrochloride (1:2). Grades: ≥95%. CAS No. 390366-87-7. Molecular formula: C15H23N5O4.2HCl. Mole weight: 410.30. | |
| H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-Me-Lys-Thr-Cys-2-Nal-NH2 | H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-Me-Lys-Thr-Cys-2-Nal-NH2 is the somatostatin-14 analog, with a high affinity of 5.98 nM for somatostatin receptor subtype 5 (SST5) (1.4 nM for somatostatin-14). It is the first antagonist with high affinity for SST5. Synonyms: H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-Me-Lys-Thr-Cys-2-Nal-NH2 (Disulfide bridge: Cys2-Cys7); 4-chloro-L-phenylalanyl-D-cysteinyl-3-(3-pyridyl)-L-alanyl-D-tryptophyl-N-methyl-L-lysyl-L-threonyl-L-cysteinyl-3-(2-naphthyl)-L-alaninamide (2->7)-disulfide; H-Phe(4-Cl)-D-Cys(1)-3Pal-D-Trp-N(Me)Lys-Thr-Cys(1)-2Nal-NH2; PRL-3195; 4-Cpa-cyclo(D-Cys-3-Pal-D-Trp-MeLys-Thr-Cys)-2-Nal-NH2. Grades: ≥90%. CAS No. 341519-04-8. Molecular formula: C58H69ClN12O9S2. Mole weight: 1177.83. | |
| H-Phe-Pro-Ala-pNA | Synonyms: FPA-pNA; L-Phenylalanyl-L-prolyl-N-(4-nitrophenyl)-L-alaninamide. CAS No. 201738-99-0. Molecular formula: C23H27N5O5. Mole weight: 453.49. | |
| H-Val-Ala-pNA | Synonyms: L-Alaninamide, L-valyl-N-(4-nitrophenyl). CAS No. 87810-63-7. Molecular formula: C14H20N4O4. Mole weight: 308.33. | |
| Isosulfazecin | Isosulfazecin is a beta-lactam antibiotic produced by the strain of Pseudomonas mesoacidophila sp. nov. Its anti-gram-positive bacteria effect is similar to SZ (Sulfazecin), but its anti-gram-negative bacteria activity is weaker than SZ. Synonyms: (R)-D-gamma-Glutamyl-N-(3-methoxy-2-oxo-1-sulfo-3-azetidinyl)-L-alaninamide; (3R) -2-Oxo-3-methoxy-3beta- [ [N- [ (4R) -4-amino-4-carboxybutyryl] alanyl] amino] azetidine-1-sulfonic acid. Grades: >98%. CAS No. 77900-75-5. Molecular formula: C12H20N4O9S. Mole weight: 396.38. | |
| L-Alanine amide hydrobromide | Synonyms: L-Ala-NH2 HBr; (S)-2-Aminopropanamide hydrobromide; Propanamide,2-amino-,hydrobromide (1:1),(2S); L-Alaninamide hydrobromide. Grades: ≥ 98% (HPLC). CAS No. 102029-80-1. Molecular formula: C3H8N2O·HBr. Mole weight: 169.02. | |
| L-Alanine amide hydrochloride | L-Alanine Amide is used for preparation of novel amide derivatives of steroidal[3,2-c]pyrazole compounds with glucocorticoid activity. Synonyms: L-Ala-NH2 HCl; Ala-NH2 HCl; H-Ala-NH2 HCl; L-Alanamine Hydrochloride; L-Alaninamide Hydrochloride; (S)-2-Aminopropanamide hydrochloride. Grades: ≥ 98% (HPLC). CAS No. 33208-99-0. Molecular formula: C3H8N2O·HCl. Mole weight: 124.60. | |
| LY-411575 | LY-411575, also known as LSN-411575, is a potent, cell-permeable γ-secretase inhibitor (IC50 = 0.078 nM/0.082 nM in membrane-assay/in cell-basedγ-secretase assays) and also inhibits Notch clevage (IC50 = 0.39 nM). Synonyms: LY 411575; LY-411575; LY411575; LSN-411575; LSN 411575; LSN411575. (2S)-2-[[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide; LY 411,575; LY 411575; LY 450139; LY-411,575; LY-411575; LY411,575; LY411575; LY450139; N2-((2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-L-alaninamide; N2-(2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)alaninamide; Semagacestat; 209984-57-6. Grades: >98%. CAS No. 209984-57-6. Molecular formula: C26H23F2N3O4. Mole weight: 479.48. | |
| M40 | M40 is a potent, non-selective antagonist of galanin receptor, and has no effect on chow or fat intake. Synonyms: M 40; M-40; H-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Pro-Pro-Ala-Leu-Ala-Leu-Ala-NH2; L-Alaninamide, glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-; Glycyl-L-tryptophyl-L-threonyl-L-leucyl-L-asparaginyl-L-seryl-L-alanylglycyl-L-tyrosyl-L-leucyl-L-leucylglycyl-L-prolyl-L-prolyl-L-prolyl-L-alanyl-L-leucyl-L-alanyl-L-leucyl-L-alaninamide; M 40 (peptide). Grades: ≥95%. CAS No. 143896-17-7. Molecular formula: C95H146N22O24. Mole weight: 1980.31. | |
| Marfey's Reagent | Used for chiral amino acid analysis. Group: Biochemicals. Alternative Names: Nα-(2,4-Dinitro-5-fluorophenyl)-L-alaninamide; 1-Fluoro-2,4-dinitrophenyl-5-L-alanine Amide; FDAA; Marfeys Reagent. Grades: Highly Purified. CAS No. 95713-52-3. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C?H?FN?O?, Molecular Weight: 272.19. US Biological Life Sciences. | Worldwide |
| MCL 0020 | MCL 0020 is a selective melanocortin MC4 receptor antagonist with IC50 value of 11.63nM at MC4 receptor. It shows anxiolytic-like activity in vivo. Synonyms: MCL 0020; MCL0020; MCL-0020; N-Acetyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-3-(2-naphthalenyl)-L-alaninamide. Grades: >98%. CAS No. 475498-26-1. Molecular formula: C34H39N7O4. Mole weight: 609.73. | |
| N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH | N-[(RS)-1-Carboxy-3-phenyl-propyl]-Ala-Ala-Phe-4-Abz-OH is a specific inhibitor of thimet oligopeptidase (soluble metalloendopeptidase, EC 3.4.24.15) with a Ki of 0.027±0.003 μM. Neprilysin (Endopeptidase-2, EC 3.4.24.11) converts it into a potent inhibitor of angiotensin-converting enzyme (ACE). Synonyms: Cpp-AAF-pAb; Cfp-aaf-pab; N-(1-Carboxy-3-phenylpropyl)-ala-ala-phe-p-aminobenzoate; N-(1-Carboxy-3-phenylpropyl)-alanyl-alanyl-phenylalanine-4-aminobenzoate; L-Phenylalaninamide, N-(1-carboxy-3-phenylpropyl)-L-alanyl-L-alanyl-N-(4-carboxyphenyl)-; N-(1-Carboxy-3-phenylpropyl)-L-alanyl-N-{(2S)-2-[(4-carboxyphenyl)amino]-3-phenylpropanoyl}-L-alaninamide. Grades: ≥95%. CAS No. 116560-97-5. Molecular formula: C32H36N4O7. Mole weight: 588.66. | |
| pTH-Related Protein (7-34) amide (human, mouse, rat) | pTH-Related Protein (7-34) amide is a potent antagonist of the effects of pTH-related protein (1-34) in vitro and in vivo. Synonyms: L-Alaninamide,l-Leucyl-L-Leucyl-L-histidyl-L-a-aspartyl-L-Lysylglycyl-L-Lysyl-L-seryl-L-isoleucyl-L-glutaminyl-L-a-aspartyl-L-Leucyl-L-arginyl-l-arginyl-l-arginyl-l-phenylalanyl-l-phenylalanyl-l-leucy; Hypercalcemia of Malignancy Factor (7-34) amide (human, mouse, rat). Grades: 95%. CAS No. 115695-30-2. Molecular formula: C153H247N49O37. Mole weight: 3364.90. | |
| SDZ NKT 343 | SDZ NKT 343 is a highly selective human tachykinin NK1 receptor antagonist (IC50 = 0.62 and 451 nM for human and rat receptors, respectively), displaying > 130-fold selectivity over human NK2 and NK3 receptors. SDZ NKT 343 was shown to antagonize SP-induced Ca2+ efflux in vitro and inhibit mechanical hyperalgesia in vivo. Uses: Neurokinin-1 receptor antagonists. Synonyms: 1-[[(2-Nitrophenyl)amino]carbonyl]-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)-L-alaninamide. Grades: ≥98% by HPLC. CAS No. 180046-99-5. Molecular formula: C33H33N5O5. Mole weight: 579.65. | |
| Semagacestat | Semagacestat is an inhibitor of the γ-secretase complex that blocks the production of Aβ38 (IC50= 12.0 nM), Aβ40 (IC50= 12.1 nM), and Aβ42 (IC50= 10.9 nM) from H4 human glioma cells stably overexpressing human wild-type APP into the culture medium. In vitro: blocks the production of Aβ38 (IC50= 12.0 nM), Aβ40 (IC50= 12.1 nM), and Aβ42 (IC50= 10.9 nM) without affecting cell viability. In vivo: decreases hippocampal levels of both Aβ42 and Aβ40 at 10 mg/kg (22-23% reduction) and 30 mg/kg (36-41% reduction) and increases β-CTF at 0.3-10 mg/kg in a dose dependent manner with no inhibition on the processing of other γ-secretase substrates, such as Notch, N-cadherin or EphA4, in the brain, but impairs normal cognition in wild-type mice and 3-month-old Tg2576 mice failing to restore cognitive deficits in the Y-maze test. Uses: Gamma secretase inhibitors and modulators. Synonyms: (2S)-2-hydroxy-3-methyl-N-[(2S)-1-[[(5S)-3-methyl-4-oxo-2,5-dihydro-1H-3-benzazepin-5-yl]amino]-1-oxopropan-2-yl]butanamide; LY 411,575; LY 411575; LY 450139; LY-411,575; LY-411575; LY411,575; LY411575; LY450139; N2-((2S)-2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-((7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-L-alaninamide; N2-(2-(3,5-difluorophenyl)-2-hydroxyethanoyl)-N1-(5-methyl-6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)alaninamide; LY4501; LY-4501; LY 4501; LY450139; LY-450139; LY 450139; Semagacestat. 425386-60-3. Grades: >98%. CAS No. 425386-60-3. Molecular formula: C19H27N3O4. Mole weight: 361.44. | |
| Suc-Ala-Ala-Ala-Ala-Ala-pNA | Synonyms: 3-Carboxypropionyl-L-alanyl-L-alanyl-L-alanyl-L-alanyl-L-alanine-p-nitroanilide; N-(3-Carboxy-1-oxopropyl)-L-alanyl-L-alanyl-L-alanyl-L-alanyl-N-(4-nitrophenyl)-L-alaninamide; Suc Ala Ala Ala Ala Ala pNA. Grades: 95%. CAS No. 61043-68-3. Molecular formula: C25H35N7O10. Mole weight: 593.59. | |
| Z-Ile-Glu(O-t-butyl)-Ala-Leucinal | PSI is a drug that blocks the action of proteasomes, protein complexes that degrade unneeded and damaged proteins. It causes dopaminergic cell death in vitro and prevents activation of NF-κB in response to TNF-α and okadaic acid by inhibiting IκB-α degradation. Uses: Cysteine proteinase inhibitors. Synonyms: Proteasome Inhibitor I; PSI peptide; L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-isoleucyl-L-alpha-glutamyl-N-[(1S)-1-formyl-3-methylbutyl]-, 1,1-dimethylethyl ester. Grades: ≥ 90 % by HPLC. CAS No. 158442-41-2. Molecular formula: C32H50N4O8. Mole weight: 618.76. | |
| Z-Val-Ala-DL-Asp(OMe)-fluoromethylketone | Z-VAD-FMK is an irreversible tripeptide inhibitor of all caspases, useful in studies involving enzymes. Synonyms: Z-vad-FMK; N-[(Phenylmethoxy)carbonyl]-L-valyl-N-[3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-alaninamide; benzyloxycarbonyl-Val-Ala-DL-Asp(O-methyl)-fluoromethyl ketone. CAS No. 634911-81-2. Molecular formula: C22H30FN3O7. Mole weight: 467.49. | |
| Z-VDVAD-FMK | Z-VDVAD-FMK is a cell-permeant and irreversible caspase-2 inhibitor and can inhibits apoptosis in various cell lines. Synonyms: Z-VD(OMe)VAD(OMe)-FMK; Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-fluoromethyl ketone; benzyloxycarbonyl-Val-Asp(OMe)-Val-Ala-Asp(OMe)-fluoromethylketone; L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-L-|A-aspartyl-L-valyl-N-[(1S)-3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-, methyl ester; Z-Val-Asp(OMe)-Val-Ala-Asp(OMe)-FMK. Grades: ≥95%. CAS No. 210344-92-6. Molecular formula: C32H46FN5O11. Mole weight: 695.74. | |
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