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Ac-Arg-Cys-Met-5-aminopentanoyl-Arg-Val-Tyr-5-aminopentanoyl-Cys-NH2 is a full competitive MCH-1 receptor antagonist and has no agonist effect on human MCH-1 receptor even at micromolar concentrations (Kb = 3.6 nM). Synonyms: Ac-Arg-Cys-Met-Ava-Arg-Val-Tyr-Ava-Cys-NH2 (Disulfide bridge: Cys2-Cys9); L-Cysteinamide, N2-acetyl-L-arginyl-L-cysteinyl-L-methionyl-5-aminopentanoyl-L-arginyl-L-valyl-L-tyrosyl-5-aminopentanoyl-, cyclic (2→9)-disulfide. Grade: ≥95%. CAS No. 353487-64-6. Molecular formula: C49H82N16O11S3. Mole weight: 1167.49.
Acetyl-(D-Arg10,Cys11,D-Phe14,Cys17)-β-MSH (10-17) amide, a selective and highly potent β-MSH-derived melanocortin-4 receptor (MC-4R) agonist, has sub-nanomolar potency with the binding affinities of 0.55±0.06, 16.78±1.53, 56.79±4.66 and <500 nM for human MC-4R, MC-1R, MC-3R and MC-5R, respectively. Synonyms: Ac-D-Arg-Cys-Glu-His-D-Phe-Arg-Trp-Cys-NH2 (Disulfide bridge: Cys2-Cys8); N-acetyl-D-arginyl-L-cysteinyl-L-alpha-glutamyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-L-cysteinamide (2->8)-disulfide; 3-[(4R,7S,10S,13R,16S,19S,22R)-22-{[N2-Acetyl-N5-(diaminomethylene)-D-ornithyl]amino}-13-benzyl-4-carbamoyl-10-{3-[(diaminomethylene)amino]propyl}-16-(1H-imidazol-5-ylmethyl)-7-(1H-indol-3-ylmethyl)-6,9,12,15,18,21-hexaoxo-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosan-19-yl]propanoic acid; L-Cysteinamide, N2-acetyl-D-arginyl-L-cysteinyl-L-α-glutamyl-L-histidyl-D-phenylalanyl-L-arginyl-L-tryptophyl-, cyclic (2→8)-disulfide. Grade: ≥95%. CAS No. 819048-44-7. Molecular formula: C51H70N18O11S2. Mole weight: 1175.36.
Acetyl-Phe1-octreotide Acetate
Acetyl-Phe1-octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanylD-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-, acetate (salt) (9CI); Ac-D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); N-Acetyl-Phe-Octreotide Acetate. Grade: 98%. CAS No. 83795-62-4. Molecular formula: C51H68N10O11S2.xC2H4O2. Mole weight: 1061.28 (free base).
Ac-Octreotide
Ac-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: Ac-DPhe-Cys-Phe-DTrp-Lys-Thr-Cys-Thr-ol(Cys2&Cys7 bridge); N2.1-Acetyloctreotide; Ac-D-Phe-c(Cys-Phe-D-Trp-Lys-Thr-Cys)-Thr-ol; Octreotide EP Impurity I; Ac-D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); N-Acetyl-Phe-Octreotide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; L-Cysteinamide, N-acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-; N-Acetyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2→7)-disulfide; D-Phe(Ac)-Octreotide; Ac-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); Acetyl-Octreotide; Acetyl-Phe1-octreotide; N-Acetyl-D-phenylalanyl-L-hemicystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-hemicystyl-L-threoninol cyclic (2→7)-disulfide. Grade: ≥95%. CAS No. 83795-61-3. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28.
Alpha-conotoxin si
Alpha-conotoxin si. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ALPHA-CONOTOXIN SI;ALPHA-CGTX SI;H-ILE-CYS-CYS-ASN-PRO-ALA-CYS-GLY-PRO-LYS-TYR-SER-CYS-NH2;ILE-CYS-CYS-ASN-PRO-ALA-CYS-GLY-PRO-LYS-TYR-SER-CYS-NH2;L-Cysteinamide, L-isoleucyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinylglycyl-L-pro. Product Category: Heterocyclic Organic Compound. CAS No. 115797-06-3. Molecular formula: C55H84N16O16S4. Mole weight: 1353.61. Product ID: ACM115797063. Alfa Chemistry ISO 9001:2015 Certified.
D-allo-Thr(6)-Octreotide
D-allo-Thr(6)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: DPhe-Cys-Phe-DTrp-Lys-DaThr-Cys-Thr-ol(Cys2&Cys7 bridge); [6-D-allothreonine]octreotide; DPhe-CF-DTrp-K-DaThr-C-Thr-ol(Cys2&Cys7 bridge); Octreotide EP Impurity A; (D-Phe)-Cys-Phe-(D-Trp)-Lys-(Dallo-Thr)-Cys-Thr-Ol (Disulfide bond Cys2/Cys7); D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-allo-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); D-Phe-Cys-Phe-D-Trp-Lys-D-allo-Thr-Cys-Thr-ol (Disulfide Bridge between Cys2-Cys7); Octreotide impurity A; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-allo-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide. Grade: ≥95%. CAS No. 1546983-12-3. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
D-Asp4-Eptifibatide
An impurity of Eptifibatide. Eptifibatide is a glycoprotein IIb/IIIa inhibitor used primarily to prevent blood clots in patients with acute coronary syndromes (ACS) and during percutaneous coronary interventions (PCI). Synonyms: Mpr-Har-Gly-DAsp-Trp-Pro-Cys-NH2(Mpr1&Cys7 bridge); Mpr-Har-G-DAsp-WPC-NH2(Mpr&Cys bridge); deamino-Cys-hArg-Gly-D-Asp-Trp-Pro-Cys-NH2 (Disulfide bridge: Cys1-Cys7); Deamino-cysteinyl-L-homoarginyl-glycyl-D-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide (1->7)-disulfide; [D-Asp]4-Eptifibatide; [D-Asp4]-Eptifibatide; D-Asp(4)-Eptifibatide; 4-D-Asp-Eptifibatide; L-Cysteinamide, N-(3-mercapto-1-oxopropyl)-6-[(aminoiminomethyl)amino]-L-norleucylglycyl-D-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→6)-thioether. Grade: ≥95%. CAS No. 3079028-51-3. Molecular formula: C35H49N11O9S2. Mole weight: 831.97.
D-Cys(2)-Octreotide
D-Cys(2)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: DPhe-DCys-Phe-DTrp-Lys-Thr-Cys-Thr-ol(Cys2&Cys7 bridge); [2-D-Cysteine]octreotide; DPhe-DCys-F-DTrp-KTC-Thr-ol(Cys2&Cys7 bridge); Octreotide EP Impurity G; D-Phenylalanyl-D-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); Octreotide Impurity-6; H-D-Phe-D-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); D-Phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2→7)-disulfide; L-Cysteinamide, D-phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-; L-Cysteinamide, D-phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide. Grade: ≥95%. CAS No. 108102-47-2. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
Des-D-Phe(1)-Octreotide
Des-D-Phe(1)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys1-Cys6); Octreotide Impurity-F; H-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys1-Cys6); L-Cysteinamide, L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (1→6)-disulfide. Molecular formula: C40H57N9O9S2. Mole weight: 872.07.
Des-D-Trp(4)-Octreotide
Des-D-Trp(4)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys6); Octreotide Impurity-G; H-D-Phe-Cys-Phe-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys6); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→6)-disulfide. Molecular formula: C38H56N8O9S2. Mole weight: 833.03.
(Des-L-threoninol8)-Octreotide amide
(Des-L-threoninol8)-Octreotide amide is a potential impurity of octreotide. Octreotide is a synthetic somatostatin analog used to treat conditions involving excessive hormone production. It is administered via subcutaneous or intravenous injection and is effective in managing acromegaly, carcinoid syndrome, and Zollinger-Ellison syndrome. Synonyms: DPhe-Cys-Phe-DTrp-Lys-Thr-Cys-NH2(Cys2&Cys7 bridge); H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-NH2 (Disulfide bridge: Cys2-Cys7); D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinamide cyclic (2-7)-disulfide; DPhe-CF-DTrp-KTC-NH2(Cys2&Cys7 bridge); (Des-Thr-ol8)-Octreotide amide; [Des-Thr-ol8]-Cys7-amide-Octreotide; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-, cyclic (2→7)-disulfide. Grade: ≥95%. CAS No. 79486-60-5. Molecular formula: C45H58N10O8S2. Mole weight: 931.13.
Des-Lys(5)-Octreotide
Des-Lys(5)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys6); Octreotide Impurity-H; H-D-Phe-Cys-Phe-D-Trp-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys6); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→6)-disulfide. Molecular formula: C43H54N8O9S2. Mole weight: 891.07.
Des-Thr6-Octreotide
An impurity of Octreotide. Octreotide is a synthetic long-acting cyclic octapeptide that inhibits growth hormone, glucagon and insulin more effectively than somatostatin. Synonyms: DPhe-Cys-Phe-DTrp-Lys-Cys-Thr-ol(Cys2&Cys6 bridge); D-Phe-c(Cys-Phe-D-Trp-Lys-Cys)-Thr-ol; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-cysteinyl-L-threoninol (2->6)-disulfide; [Des-Thr6]-Octreotide; Des-Thr(6)-Octreotide; D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys6); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→6)-disulfide, [R-(R*,R*)]-. Grade: ≥95%. CAS No. 159660-05-6. Molecular formula: C45H59N9O8S2. Mole weight: 918.14.
D-Har2-Eptifibatide
An impurity of Eptifibatide. Eptifibatide is a glycoprotein IIb/IIIa inhibitor used primarily to prevent blood clots in patients with acute coronary syndromes (ACS) and during percutaneous coronary interventions (PCI). Synonyms: Mpr-DHar-Gly-Asp-Trp-Pro-Cys-NH2(Mpr1&Cys7 bridge); Mpr-DHar-GDWPC-NH2(Mpr&Cys bridge); (D-Homo-Arg)2 Eptifibatide impurity; Mpr-(D-Homo-Arg)-Gly-Asp-Trp-Pro-Cys-NH2 (Disulfide bond Mpr1/Cys7); Mpr(D-Homo-Arg)GDWPC-NH2 (Disulfide bond Mpr1/Cys7); deamino-Cys-D-hArg-Gly-Asp-Trp-Pro-Cys-NH2 (Disulfide bridge: Cys1-Cys7); Deamino-cysteinyl-D-homoarginyl-glycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide (1->7)-disulfide; Eptifibatide Impurity 4; D-Har Eptifibatide; N6-Amidino-N2-(3-mercaptopropionyl)-D-lysylglycyl-D-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1-6)-disulfide; (D-Homo-Arg)2 Eptifibatide; D-hArg2-Eptifibatide; [D-hArg]2-Eptifibatide; [D-Har2]-Eptifibatide; L-Cysteinamide, N-(3-mercapto-1-oxopropyl)-6-[(aminoiminomethyl)amino]-D-norleucylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→6)-thioether. Grade: ≥95%. CAS No. 3079028-40-0. Molecular formula: C35H49N11O9S2. Mole weight: 831.97.
D-Lactolactoyl-Lys5-Octreotide
An impurity of Octreotide. Octreotide is a synthetic long-acting cyclic octapeptide that inhibits growth hormone, glucagon and insulin more effectively than somatostatin. Synonyms: DPhe-Cys-Phe-DTrp-Lys(D-Lactide)-Thr-Cys-Thr-ol(Cys2&Cys7 bridge); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-N6-[(2R)-2-[(2R)-2-hydroxy-1-oxopropoxy]-1-oxopropyl]-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; DPhe-Cys-Phe-DTrp-Lys(D-Lactide)-Thr-Cys-Thr-ol(Cys2&Cys7 bridge); D-Lactolactoyl-Lys-Octreotide; D-Lactide-Lys5-Octreotide. Grade: ≥95%. CAS No. 2821715-05-1. Molecular formula: C55H74N10O14S2. Mole weight: 1163.37.
DOTA-NOC
DOTA-NOC is a potent chelating agent extensively used in radiopharmaceuticals for the targeted imaging and therapy of neuroendocrine tumors. By combining with diverse radiometals, such as lutetium-177 or yttrium-90, it generates therapeutic agents that specifically bind to neuroendocrine tumor cells. The DOTA-NOC derivatives have displayed remarkable specificity and affinity for somatostatin receptors, endowing it with a unique potential for cancer therapy. Its diverse applications stem from its impressive properties, which include high burstiness in sentence structure and an elevated level of perplexity in its descriptions. Synonyms: L-Cysteinamide, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; DOTA-[Nal3]-octreotide; H-D-Phe(DOTA)-Cys(1)-Nal-D-Trp-Lys-Thr-Cys(1)-Thr-ol; DOTA-D-Phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-alanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol (2->7)-disulfide. Grade: 95%. CAS No. 619300-53-7. Molecular formula: C69H94N14O17S2. Mole weight: 1455.70.
D-Phe(3)-Octreotide
D-Phe(3)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: D-phenylalanyl-L-cystyl-D-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); D-Phe-Cys-D-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide Bridge between Cys2-Cys7); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-D-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; D-phenylalanyl-L-cysteinyl-D-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol (2->7)-disulfide. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
D-Thr(6)-Octreotide
D-Thr(6)-0ctreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: DPhe-Cys-Phe-DTrp-Lys-DThr-Cys-Thr-ol(Cys2&Cys7 bridge); D-Thr6-Octreotide; [D-Thr6]-Octreotide; D-Phe-c(Cys-Phe-D-Trp-Lys-D-Thr-Cys)-Thr-ol; H-D-Phe-Cys(1)-Phe-D-Trp-Lys-D-Thr-Cys(1)-Thr-ol; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-threonyl-L-cysteinyl-L-threoninol (2->8)-disulfide; D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-; Octreotide impurity-10; H-D-Phe-Cys-Phe-D-Trp-Lys-D-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide. Grade: ≥95%. CAS No. 87759-89-5. Molecular formula: C49H66N10O10S2. Mole weight: 1019.25.
D-Thr(6)-Octreotide Acetate
D-Thr(6)-0ctreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-D-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-,cyclic (2→7)-disulfide, [R-(R*,R*)]-, acetate (salt) (9CI). Grade: 95%. CAS No. 87759-90-8. Molecular formula: C49H66N10O10S2.xC2H4O2.
Edotreotide
Edotreotide is a substance used in the treatment and diagnosis of certain types of cancer. Synonyms: L-Cysteinamide, N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; L-Cysteinamide, N-[[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; (DOTA-D-Phe1,Tyr3)octreotide; DOTATOC; SDZ-SMT 487; SMT 487; SomaKit TOC; DOTA-(Tyr3)-Octreotide; SMT-487; SMT487; DOTA-d-Phe1-Tyr3-octreotide; DOTA-TOC. Grade: 98%. CAS No. 204318-14-9. Molecular formula: C65H92N14O18S2. Mole weight: 1421.64.
Eptifibatide
An arginin-glycin-aspartat-mimetic, reversibly binds to platelets to reduce the risk of cardiac ischemic events. Uses: Platelet aggregation inhibitors. Synonyms: L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→6)-disulfide; Eftifibatide; Integrelin; Integrilin; Intrifiban; Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2(Mpr&Cys bridge); Deamino-cysteinyl-L-homoarginyl-glycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide (1->7)-disulfide; deamino-Cys-hArg-Gly-Asp-Trp-Pro-Cys-NH2 (Disulfide bridge: Cys1-Cys7). Grade: 98%. CAS No. 188627-80-7. Molecular formula: C35H49N11O9S2. Mole weight: 831.97.
Eptifibatide acetate
Eptifibatide acetate, an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class, is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue. It reversibly binds to platelets to reduce the risk of cardiac ischemic events. Synonyms: L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→6)-disulfide, acetate (1:x); deamino-Cys(1)-hArg-Gly-Asp-Trp-Pro-Cys(1)-NH2.xCH3CO2H; Deamino-cysteinyl-L-homoarginyl-glycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide (1->7)-disulfide acetate salt; Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 (Mpr&Cys bridge) acetate. Grade: ≥95%. CAS No. 881997-86-0. Molecular formula: C35H49N11O9S2.xC2H4O2. Mole weight: 831.97 (free base).
An impurity of Eptifibatide. Eptifibatide is a glycoprotein IIb/IIIa inhibitor used primarily to prevent blood clots in patients with acute coronary syndromes (ACS) and during percutaneous coronary interventions (PCI). Synonyms: Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2(Mpr&Cys,Cys&Mpr bridge); Mpr-Har-GDWPC-NH2(Mpr&Cys,Cys&Mpr bridge); Eptifibatide (Dimer, unparallel); deamino-Cys-hArg-Gly-Asp-Trp-Pro-Cys-NH2.deamino-Cys-hArg-Gly-Asp-Trp-Pro-Cys-NH2 (Disulfide bridge: Cys1-Cys7', Cys7-Cys1'); L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, bimol. cyclic (1→6'),(6→1')-bis(disulfide); Eptifibatide Dimer; N6-Amidino-N2-(3-mercaptopropionyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1-6'),(6-1')-bis(disulfide); Eptifibatide Impurity 3. Grade: ≥95%. CAS No. 1505450-99-6. Molecular formula: C70H98N22O18S4. Mole weight: 1663.93.
Eptifibatide Dimer (parallel)
An impurity of Eptifibatide. Eptifibatide is a glycoprotein IIb/IIIa inhibitor used primarily to prevent blood clots in patients with acute coronary syndromes (ACS) and during percutaneous coronary interventions (PCI). Synonyms: Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2(Mpr&Mpr,Cys&Cys bridge); Mpr-Har-GDWPC-NH2(Mpr&Mpr,Cys&Cys bridge); Eptifibatide Dimer(parallel); deamino-Cys-hArg-Gly-Asp-Trp-Pro-Cys-NH2.deamino-Cys-hArg-Gly-Asp-Trp-Pro-Cys-NH2 (Disulfide bridge: Cys1-Cys1', Cys7-Cys7'); L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, bimol. cyclic (1→1'),(6→6')-bis(disulfide); Eptifibatide Dimer; N6-Amidino-N2-(3-mercaptopropionyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-Lprolyl-L-cysteinamide, cyclic(1-1'),(6-6')-bis(disulfide). Grade: ≥95%. CAS No. 1505451-00-2. Molecular formula: C70H98N22O18S4. Mole weight: 1663.93.
Eptifibatide monoacetate
Eptifibatide monoacetate, an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class, is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue. It reversibly binds to platelets to reduce the risk of cardiac ischemic events. Synonyms: L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→6)-disulfide, acetate (1:1); deamino-Cys(1)-hArg-Gly-Asp-Trp-Pro-Cys(1)-NH2.CH3CO2H; Deamino-cysteinyl-L-homoarginyl-glycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide (1->7)-disulfide acetic acid; Eptifibatide acetate; Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 (Mpr&Cys bridge) acetate. Grade: ≥95%. CAS No. 1248559-53-6. Molecular formula: C35H49N11O9S2.C2H4O2. Mole weight: 892.02.
Gly double addition eptifibatide
An impurity of Eptifibatide. Eptifibatide is a glycoprotein IIb/IIIa inhibitor used primarily to prevent blood clots in patients with acute coronary syndromes (ACS) and during percutaneous coronary interventions (PCI). Synonyms: Mpr-Har-Gly-Gly-Asp-Trp-Pro-Cys-NH2(Mpr1&Cys8 bridge); Mpr-Har-GGDWPC-NH2(Mpr&Cys bridge); L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→7)-disulfide; deamino-Cys-hArg-Gly-Gly-Asp-Trp-Pro-Cys-NH2 (Disulfide bridge: Cys1-Cys8); Deamino-cysteinyl-L-homoarginyl-glycyl-glycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide (1->8)-disulfide; Di-Gly3-Eptifibatide; (+Gly3)-Eptifibatide. Grade: ≥95%. CAS No. 868242-25-5. Molecular formula: C37H52N12O10S2. Mole weight: 889.02.
L-Threoninol(Ac)-8-Octreotide
L-Threoninol(Ac)-8-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: DPhe-Cys-Phe-DTrp-Lys-Thr-Cys-Thr-ol-Ac(Cys2&Cys7 bridge); DPhe-CF-DTrp-KTC-Thr-ol-Ac(Cys2&Cys7 bridge); O1.8-Acetyloctreotide; Octreotide EP Impurity F; D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L(Acetyl)-threoninol (Disulfide Bridge between Cys2-Cys7); Octreotide Impurity F; H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Ac-Thr-ol (Disulfide bridge: Cys2-Cys7); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[1-[(acetyloxy)methyl]-2-hydroxypropyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-; O-Acetyl Octreotide; [O1(AC)]8-Octreotide; (L-Threoninol(Ac)8)-Octreotide. Grade: ≥95%. CAS No. 133304-81-1. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28.
Lys(Ac)-Octreotide
Lys(Ac)-Octreotide is an impurity of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Uses: Radiopharmaceuticals. Synonyms: DPhe-Cys-Phe-DTrp-Lys(Ac)-Thr-Cys-Thr-ol(Cys2&Cys7 bridge); N6.5-Acetyloctreotide; D-Phe-c(Cys-Phe-D-Trp-Lys(Ac)-Thr-Cys)-Thr-ol; Lys(Ac) 5 Octreotide; D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl(acetyl)-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-N6-acetyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-N6-acetyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2→7)-disulfide; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-N6-acetyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-; Octreotide EP Impurity H; Octreotide Impurity H; Acetyl-Lys5-octreotide; D-Phenylalanyl-L-hemicystyl-L-phenylalanyl-D-tryptophyl-(N-acetyl)-L-lysyl-L-threonyl-L-hemicystyl-L-threoninol cyclic (2→7)-disulfide. Grade: ≥95%. CAS No. 173606-11-6. Molecular formula: C51H68N10O11S2. Mole weight: 1061.28.
Mutacin 1140
Mutacin 1140 is an antimicrobial peptide found in Streptococcus mutans, and has antibacterial activity against a broad spectrum of Gram-positive bacteria. Synonyms: MU1140; L-Phenylalanyl-L-lysyl-D-cysteinyl-L-tryptophyl-2,3-didehydroalanyl-L-leucyl-L-cysteinyl-(2S)-2-amino-3-mercaptobutanoyl-L-prolylglycyl-L-cysteinyl-L-alanyl-L-arginyl-(2Z)-2-amino-2-butenoylglycyl-D-cysteinyl-L-phenylalanyl-L-asparaginyl-D-cysteinyl-L-tyrosyl-N-[(1Z)-2-mercaptoethenyl]-L-cysteinamide, cyclic (3-7),(8-11),(16-213),(19-211)-tetrakis(thioether); Lantibiotic mutacin-1140; lanA; Mutacin III. Grade: >85%. CAS No. 218133-96-1. Molecular formula: C103H138N28O23S4. Mole weight: 2264.65.
Octreotide Acetate
Octreotide acetate is a long-acting octapeptide with pharmacologic actions similars to the natural hormone somatostatin. It is a more potent inhibitor of growth hormone, glucagon, and insulin than the natural hormone. It was approved as an injectable depot formulation used for acromegaly, gigantism, thyrotropinoma, diarrhea and flushing episodes associated with carcinoid syndrome, and diarrhea in patients with vasoactive intestinal peptide-secreting tumors. It is a gastric antisecretory agent andcould inhibit the secretion of insulin and glucagon. It reduces production of IGF-1 and IGF-2 by the liver by modulation of growth-hormone secretion from the pituitary gland. It decreased the urinary excretion of uric acid as well as the plasma concentrations of glucagon and insulin. It decreased the urinary excretion of sodium and chloride without significiant influence on creatinine clearance, while the concentrations of lactic acid, pyruvic acid in blood, and cyclic AMP in plasma were not changed. It was first synthesized in 1979 by the chemist Wilfried Bauer and was developed by Novartis Pharmaceuticals. Uses: Antineoplastic agents, hormonal. Synonyms: L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, acetate (1:x); H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol.xCH3CO2H (Disulfide Bridge between Cys2-Cys7); D-phen
Octapeptide analog of Somatostatin. A gastric antisecretory agent. Used in treatment of acromegaly. Group: Biochemicals. Alternative Names: SMS 201995; Sandostatin; D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-Alcohol; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2-7)-disulfide acetate. Grades: Highly Purified. CAS No. 79517-01-4. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C49H66N10O10S2, Molecular Weight: 1019.24. US Biological Life Sciences.
Worldwide
Octreotide (Dimer, Antiparallel)
Octreotide (Dimer, Antiparallel) is a potential impurity of octreotide. Synonyms: (H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol)2 (Disulfide bridge: Cys2A-Cys7B, Cys7A-Cys2B); D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol (2->7'),(7->2')-bis(disulfide) compound with D-phenylalanyl-D-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, bimol. cyclic (2→7'),(7→2')-bis(disulfide). Grade: ≥95%. CAS No. 1926163-78-1. Molecular formula: C98H132N20O20S4. Mole weight: 2038.49.
Octreotide (Dimer, Parallel)
Octreotide (Dimer, Parallel) is a potential impurity of octreotide. Synonyms: (H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol)2 (Disulfide bridge: Cys2A-Cys2B, Cys7A-Cys7B); D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol (2->2'),(7->7')-bis(disulfide) compound with D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, bimol. cyclic (2→2'),(7→7')-bis(disulfide). Grade: ≥95%. CAS No. 1926163-80-5. Molecular formula: C98H132N20O20S4. Mole weight: 2038.49.
Octreotide-[D-Phe-d8]
Octreotide-[D-Phe-d8] is the labelled analogue of Octreotide, which is a synthetic long-acting cyclic octapeptide used as a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Synonyms: Octreotide-d8; Octreotide-D-Phe-d8; Octreotide D8; D-phenylalanyl(D8)-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cystyl-L-threoninol (Disulfide Bridge between Cys2-Cys7); H-D-Phe(D8)-Cys-Phe-D-Trp-Lys-Thr-Cys-Thr-ol (Disulfide bridge: Cys2-Cys7); L-Cysteinamide, D-phenylalanyl(D8)-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide. Molecular formula: C49H58D8N10O10S2. Mole weight: 1027.29.
[Tyr3,Lys5(Boc)]Octreotide
An impurity of Octreotide. Octreotide is a synthetic long-acting cyclic octapeptide that inhibits growth hormone, glucagon and insulin more effectively than somatostatin. Synonyms: L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-N6-[(1,1-dimethylethoxy)carbonyl]-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide; L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-N6-[(1,1-dimethylethoxy)carbonyl]-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-, cyclic (2→7)-disulfide, [R-(R*,R*)]-; H-D-Phe-Cys-Tyr-D-Trp-Lys(Boc)-Thr-Cys-Thr-ol,cyclic disulfide; H-D-Phe-Cys(1)-Tyr-D-Trp-Lys(Boc)-Thr-Cys(1)-Thr-ol; D-Phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-N6-tert-butoxycarbonyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol (2->7)-disulfide; [Tyr3,Lys5(Boc)]Octreotide acetate. Grade: ≥95%. CAS No. 147790-89-4. Molecular formula: C54H74N10O13S2. Mole weight: 1135.36.
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