Lipoprotein Suppliers USA
Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
Product | Description | |
---|---|---|
1-Myristoyl-sn-glycero-3-phosphocholine Quick inquiry Where to buy Suppliers range | 1-Myristoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine derivative, which is found in plasma and oxidized low-density lipoprotein (Ox-LDL). It can be used as a biomarker for detecting lipid metabolism. Synonyms: 3-sn-Lysophosphatidylcholine; lysomyristoyl phosphatidylcholine; Lysolecithin,tetradecanoyl; 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphatidylcholine; M-lyso-PC; 1-Tetradecanoyl-sn-glycero-3-phosphocholine; (7R)-,7-Dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphatricosan-1-aminium Inner salt 4-Oxide; (R)-,7-Dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphatricosan-1-aminium Inner salt 4-Oxide; 1-Myristoyl-L-α-phosphorylcholine; 1-Tetradecanoyl-sn-glycero-3-phosphorylcholine; L-α-Myristoyllysophosphatidylcholine; M-LysoPC; Myristoyl L-α-lysolecithin; Myristoyl L-α-Lysophosphatidylcholine; LPC(14:0); LyPC(14:0); PC(14:0/0:0). Grades: >99% by HPLC. CAS No. 20559-16-4. Molecular formula: C22H46NO7P. Mole weight: 467.58. | |
1-Palmitoyl-2-[3- (diphenylhexatriene) propanoyl]-sn-phosphatidylcholine-d9 Quick inquiry Where to buy Suppliers range | 1-Palmitoyl-2-[3- (diphenylhexatriene) propanoyl]-sn-phosphatidylcholine-d9 is labelled 1-Palmitoyl-2-[3- (diphenylhexatriene) propanoyl]-sn-phosphatidylcholine (P156600) which is a phosphatidylcholine containing fluorescent probe used in the the continuous determination of surface lipid oxidation of lipoproteins and plasma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C45H59D9NO8P, Molecular Weight: 791.05. US Biological Life Sciences. | Worldwide |
2-[4-(4-Chlorobenzoyl)phenoxy]-2-methyl-N-(1-methylethyl)-propanamide Quick inquiry Where to buy Suppliers range | 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methyl-N-(1-methylethyl)-propanamide is an intermediate in synthesizing Fenofibric Acid 1,1-Dimethyl-2-(1-methylethoxy)-2-oxoethyl Ester (F248680), which is an impurity of Febofibrate (F248640). Febofibrate is an antilipemic. It is a lipid regulating drug. Increases high density lipoprotein levels by reducing cholesteryl ester transfer protein expresion. Group: Biochemicals. Grades: Highly Purified. CAS No. 1316847-19-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C20H22ClNO3. US Biological Life Sciences. | Worldwide |
2-(N-Ethyl-m-toluidino)ethanol Quick inquiry Where to buy Suppliers range | A 2-(N-Ethyl-m-toluidino)ethanol pigment system and lipoprotein lipase are used as a new glycerol oxidase determination method for serum triglyceride. 2-(N-Ethyl-m-toluidino)ethanol is also used in quantitative structure-activity relationship (QSAR) models that are developed to predict the aquatic toxicity of chemicals to the fathead minnow (Pimephales promelas). Group: Biochemicals. Grades: Highly Purified. CAS No. 91-88-3. Pack Sizes: 2.5g, 10g. Molecular Formula: C11H17NO, Molecular Weight: 179.26. US Biological Life Sciences. | Worldwide |
3,5-Dichloro-2-hydroxybenzenesulfonic acid, sodium salt (HDCBS-Na) Quick inquiry Where to buy Suppliers range | Chromogenic reagent for HDL cholesterol. HDL (High Density Lipoproteins) are responsible for the reverse transport of cholesterol from peripheral cells to the liver, where cholesterol is transformed to bile acids. These are excreted into the intestine via the biliary tract. Monitoring of HDL-cholesterol in serum is of clinical importance because there is an inverse correlation between serum HDL-cholesterol concentrations and the risk of atherosclerotic disease. It is believed that elevated HDL-cholesterol concentrations offer protection against coronary heart disease, while reduced HDL-cholesterol concentrations, particularly in conjunction with elevated triglycerides, increase cardiovascular risk. Group: Biochemicals. Grades: Highly Purified. CAS No. 54970-72-8. Pack Sizes: 50g, 100g. US Biological Life Sciences. | Worldwide |
3'-Cholesterol CPG 1000 Quick inquiry Where to buy Suppliers range | 3'-Cholesterol CPG 1000 is a highly sought-after phosphoramidite building block, coveted by experts in the field for its impressive versatility and usefulness. Boasting numerous applications within the biomedical industry, its primary function is in the synthesis of oligonucleotides with cholesterol conjugates. Scientists and researchers alike utilize this remarkable product in their study of lipoprotein metabolism, and its effectiveness in the treatment of hypercholesterolemia-associated diseases such as atherosclerosis cannot be overstated. | |
3'-Cholesteryl-frits column (100nmol) Quick inquiry Where to buy Suppliers range | 3'-Cholesteryl-frits column (100nmol) represents a sophisticated stationary phase utilized for liquid chromatography, that accurately separates and purifies cholesterol-containing molecules in diverse biological samples. The multifunctional and versatile column enables a comprehensive examination of lipoprotein composition, the diagnosis of lipid metabolism disorders, and offers a profound scope for developing therapeutic agents to combat cardiovascular diseases. Synonyms: 3'-Cholesteryl-frits column. | |
4-Chloro-4-hydroxybenzophenone Quick inquiry Where to buy Suppliers range | The impurity of Fenofibric acid (42017-89-0), the active metabolite of fenofibrate which increases Apolipoprotein A-I-Mediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptor-dependent manner. Group: Biochemicals. Alternative Names: (4-Chlorophenyl) (4-hydroxyphenyl) methanone; 4-(4-chlorobenzoyl)phenol. Grades: Highly Purified. CAS No. 42019-78-3. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
Acaterin Quick inquiry Where to buy Suppliers range | Acarbose is an acyl-CoA isolated from Pseudomonas species. A92. In the presence of oxidized low-density lipoprotein in macrophages J744, the synthesis of cholesterol enzymes is inhibited, with an IC50 of 45 μmol/L, and the IC50 for inhibiting ACAT in rat liver microsomes is 120 μmol/L. Inhibition of ACAT is non-competitive Sexual. Synonyms: (2R)-4-[(1R)-1-hydroxyoctyl]-2-methyl-2H-furan-5-one; 3-(1-Hydroxyoctyl)-5-methyl-2(5H)-furanone. Grades: >98%. CAS No. 144398-20-9. Molecular formula: C13H22O3. Mole weight: 226.31. | |
all cis-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester Quick inquiry Where to buy Suppliers range | all cis-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester is an omega-3 fatty acid agent. It is important polyunsaturated fatty acid of the marine food chain. It serves as a precursor of the prostaglandin-3 and thromboxane-3 families. It differs from arachidonic acid by the extra double bond between the third and fourth carbons from the "methyl end" of the molecule. It reduces non-high-density lipoprotein cholesterol, lipoprotein-associated phospholipase A2, apolipoprotein B, very low-density lipoprotein cholesterol, and total cholesterol. It reduces the TG levels and improved other lipid parameters without significantly increasing the LDL cholesterol levels. It is used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia. It has anti-inflammatory and cardiovascular benefits. It may alter the expression of genes related to fatty acid metabolism. It was the second class of fish oil-based drug to be approved for use as a drug. It was developed by Amarin Corporation. It has been listed. Uses: All cis-5,8,11,14,17-eicosapentaenoic acid ethyl ester reduces non-high-density lipoprotein cholesterol, lipoprotein-associated phospholipase a2, apolipoprotein b, very low-density lipoprotein cholesterol, and total cholesterol. it has anti-inflammatory and cardiovascular benefits. Synonyms: Eicosapentaenoic Acid Ethyl Ester;(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester;(all-Z)-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester;cis-Eicosapentaenoic Acid Ethyl Ester;Ethyl icosapentate; Epadel;Ethyl eicosapentaenoate;Vascepa;EPA ethyl ester;Ethyl (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate. Grades: >98%. CAS No. 86227-47-6. Molecular formula: C22H34O2. Mole weight: 330.50. | |
Avasimibe Quick inquiry Where to buy Suppliers range | Avasimibe inhibits Lipoprotein(a) accumulation in the culture media of primary monkey hepatocyte in a dose-dependent manner with 11.9% -31.3% inhibition, the change is mainly associated with decreased ApoA. Uses: Cytochrome p-450 cyp3a inducers. Synonyms: CI-1011; CI 1011; CI1011; ((2,4,6-Tris(1-methylethyl)phenyl)acetyl)sulfamic acid 2,6-bis(1-methylethyl)phenyl este; Sulfamic acid, N-[2-[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl esterr. Grades: >98%. CAS No. 166518-60-1. Molecular formula: C29H43NO4S. Mole weight: 501.72. | |
Azelaoyl PAF Quick inquiry Where to buy Suppliers range | Azelaoyl-PAF is an alkyl phosphatidylcholine and is a component of the lipid pool within oxidized low-density lipoprotein (oxLDL) particles, which contain low molecular weight species. It is a potent PPARγ agonist which competes for the thiazolidinedione binding site. Synonyms: 1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine; C16-09:0 (COOH) PC; 1-O-hexadecyl-2-nonadioyl-sn-glycero-3-phosphocholine; 1-O-Hexadecyl-2-O-(9-carboxyoctanoyl)-sn-glyceryl-3-phosphocholine. Grades: >99%. CAS No. 354583-69-0. Molecular formula: C33H66NO9P. Mole weight: 651.85. | |
Berberine hydrochloride Quick inquiry Where to buy Suppliers range | Berberine hydrochloride is an isoqinoline alkaloid and acts as a COX-2 inhibitor that exhibits chemopreventive activity against colon tumor formation. Study in humans and hamsters shows that berberine reduces total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides. It also inhibits c-Jun and suppresses inflammation and cancers. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Berberine chloride; Natural Yellow 18; Benzodioxide; Berberinium chloride. Grades: ≥ 98%. CAS No. 633-65-8. Molecular formula: C20H18ClNO4. Mole weight: 371.817. | |
β-Sitosterol Quick inquiry Where to buy Suppliers range | A common sterol in plants. Isolated from wheat germ oil, corn oil. Antilipemic. Used in the treatment of prostatic adenoma. 5-alpha reductase inhibitor. β-sitosterol reduces blood levels of cholesterol, and is sometimes used in treating hypercholesterolemia. β-Sitosterol inhibits cholesterol absorption in the intestine. When the sterol is absorbed in the intestine, it is transported by lipoproteins and incorporated into the cellular membrane. Group: Biochemicals. Alternative Names: (3 β)-Stigmast-5-en-3-ol; Nimbosterol; Stigmast-5-en-3 β-ol; (-)- β-Sitosterol; (24R)-Ethylcholest-5-en-3 β-ol; (24R)-Stigmast-5-en-3 β-ol. Grades: Highly Purified. CAS No. 83-46-5. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C29H50O, Molecular Weight: 414.71. US Biological Life Sciences. | Worldwide |
Bis(2-ethylhexyl) Phthalate Quick inquiry Where to buy Suppliers range | Bis(2-ethylhexyl) Phthalate. Uses: Di(2-ethylhexyl) phthalate is a colorless to pale yellow oily liquid. Nearly odorless. (USCG, 1999);Liquid; PelletsLargeCrystals, Liquid;COLOURLESS-TO-LIGHT COLOURED VISCOUS LIQUID WITH CHARACTERISTIC ODOUR.;Colorless, oily liquid with a slight odor.;Colorless, oily liquid with a slight odor. Group: Plastic Additives; Polymers; Plasticizers. CAS No. 117-81-7. IUPAC Name: bis(2-ethylhexyl) benzene-1,2-dicarboxylate. Molecular Weight: 390.6g/mol. Molecular Formula: C24H38O4;C6H4(COOC8H17)2;C24H38O4. SMILES: CCCCC (CC)COC (=O)C1=CC=CC=C1C (=O)OCC (CC)CCCC. InChI: InChI=1S/C24H38O4/c1-5-9-13-19(7-3)17-27-23(25)21-15-11-12-16-22(21)24(26)28-18-20(8-4)14-10-6-2/h11-12,15-16,19-20H,5-10,13-14,17-18H2,1-4H3. InChIKey: BJQHLKABXJIVAM-UHFFFAOYSA-N. Boiling Point: 723 °F at 760 mm Hg (NTP, 1992);384.0 ?;384 ?;385 ?;727°F;727°F. Melting Point: -58 °F (NTP, 1992);-55.0 ?;-55 ?;-50 ?;-58°F;-58°F. Flash Point: 405 °F (NTP, 1992);420 °F (215 ?) (Open cup);215 ? o.c.;420°F (open cup);(oc) 420°F. Density: 0.98 at 77 °F (USCG, 1999);0.981 g/cu cm at 25 ?;Relative density (water = 1): 0.986;0.99;0.99. Solubility: less than 0.1 mg/mL at 72° F (NTP, 1992);1.08e-07 M;In water, 2.70X10-1 mg/L at 25 ?;LESS THAN 0.01% IN WATER @ 25 ?;Soluble in blood and fluids containing lipoproteins;MISCIBLE WITH MINERAL OIL & HEXANE;Slightly soluble in carbon tetrachloride;Solubility in water: none;(75°F): 0.00003%. Viscosity: 22 cSt at 20 ?; 386 cSt at 0 ?; 5 cSt at 100 ?. | |
CAY10485 Quick inquiry Where to buy Suppliers range | Acetyl-CoA acetyltransferase, mitochondrial, also known as acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT (Acetyl-Coenzyme A acetyltransferase) gene. Both ACAT-1 and ACAT-2 are acetyl-CoA C-acetyltransferase enzyme. CAY10485 inhibits human ACAT-1 and ACAT-2 with an IC50 of 95 and 81 μM, respectively. It also inhibits copper-mediated oxidation of low density lipoproteins. Synonyms: 3,4-dihydroxy Hydrocinnamic acid (L-Aspartic acid dibenzyl ester) amide. Grades: ≥98%. CAS No. 615264-62-5. Molecular formula: C27H27NO7. Mole weight: 477.5. | |
CAY10486 Quick inquiry Where to buy Suppliers range | Acetyl-CoA acetyltransferase, mitochondrial, also known as acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT (Acetyl-Coenzyme A acetyltransferase) gene. Both ACAT-1 and ACAT-2 are acetyl-CoA C-acetyltransferase enzyme. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins. Synonyms: 4-Hydroxycinnamic acid (L-phenylalanine methyl ester) amide. Grades: ≥98%. CAS No. 615264-52-3. Molecular formula: C19H19NO4. Mole weight: 325.4. | |
Cholesterol Concentrate, Bovine (BCC) Quick inquiry Where to buy Suppliers range | Bovine Cholesterol Concentrate is a concentrated cholesterol additive consisting mainly of bovine high density lipoproteins. The lipoproteins are substantially free of other serum proteins. Typical cholesterol concentrations are in the range of 6000 to 8000mg/dL. Group: Molecular Biology. Alternative Names: BCC; HDL; High Density Lipoprotein; HDL-C; HDL Concentrate; HDL Fraction; alpha-Lipoprotein. Grades: Molecular Biology Grade. CAS No. 57-88-5. Pack Sizes: 100mg, 1g. US Biological Life Sciences. | Worldwide |
CI 976 Quick inquiry Where to buy Suppliers range | CI 976 has been found to be a selective inhibitor of Acyl-coenzyme A and could probably lower non-high density lipoprotein (HDL)-cholesterol. Uses: Enzyme inhibitors. Synonyms: CI 976; CI-976; CI976; 2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide. Grades: ≥98% by HPLC. CAS No. 114289-47-3. Molecular formula: C23H39NO4. Mole weight: 393.57. | |
Ciprofibrate-O-β-Glucuronide Quick inquiry Where to buy Suppliers range | Ciprofibrate-O-β-Glucuronide is a derivative of Ciprofibrate. Ciprofibrate is a hypolipemic agent that is structurally related to Clofibrate. Ciprofibrate works primarily by stimulating lipoprotein lipases and hepatic lipases in the breakdown of triglyceride and cholesterol. Synonyms: 1-[2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoate]-β-D-glucopyranuronic Acid; Ciprofibrate glucuronide. Grades: > 95%. CAS No. 102623-15-4. Molecular formula: C19H22Cl2O9. Mole weight: 465.28. | |
Colesevelam hydrochloride Quick inquiry Where to buy Suppliers range | Colesevelam is a bile acid sequestrant that helps reduce elevated low-density lipoprotein cholesterol (LDL-C) in patients with primary hyperlipidemia, and also improve blood glucose balance in adults with type 2 diabetes mellitus. Synonyms: CholestaGel; GT 31-104; GT 31-104HB; Welchol. CAS No. 182815-44-7. Molecular formula: (C13H27N)n. (C12H27ClN2)n. (C3H7N)n. (C3H5ClO)n. xHCl. | |
CP-10447 Quick inquiry Where to buy Suppliers range | An inhibitor apolipoprotein B (apoB) and triglyceride secretion in human hepatoma cells (HepG2) by inhibiting MTP activity and stimulating the early ER degradation of apoB. It is useful tool for further study of the mechanisms of apoB secretion and triglyceride-rich lipoprotein assembly. Group: Biochemicals. Alternative Names: 3-(4-Bromo-2-methylphenyl)-2-methyl-4(3H)-quinazolinone; CP 10447; 3-(4-Bromo-o-tolyl)-2-methyl-4(3H)-quinazolinone. Grades: Highly Purified. CAS No. 843-93-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Darapladib Quick inquiry Where to buy Suppliers range | Darapladib (SB-480848) is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.25 nM. Synonyms: SB-480848; SB 480848; SB480848; Darapladib. Grades: >98%. CAS No. 356057-34-6. Molecular formula: C36H38F4N4O2S. Mole weight: 666.77. | |
Dextrothyroxine sodium Quick inquiry Where to buy Suppliers range | Dextrothyroxine is an antihyperlipidemic. It stimulates the formation of low-density lipoprotein (LDL) and increases the catabolism of LDL thereby leading to increased excretion of cholesterol and bile acids via the biliary route. Synonyms: D-Thyroxine sodium salt; dynothel; Debetrol; 3:5:3':5'-tetraiodo-d-thyroninesodium; biotirmone; choloxin; dethyrona; detyroxin; dextroid; dextrothyroxinesodium; dextroxin. CAS No. 137-53-1. Molecular formula: C15H10I4NNaO4. Mole weight: 798.86. | |
Dioctyl Phthalate Quick inquiry Where to buy Suppliers range | Dioctyl Phthalate. Uses: Di(2-ethylhexyl) phthalate is a colorless to pale yellow oily liquid. Nearly odorless. (USCG, 1999);Liquid; PelletsLargeCrystals, Liquid;COLOURLESS-TO-LIGHT COLOURED VISCOUS LIQUID WITH CHARACTERISTIC ODOUR.;Colorless, oily liquid with a slight odor.;Colorless, oily liquid with a slight odor. Group: Plasticizers. CAS No. 117-81-7. IUPAC Name: bis(2-ethylhexyl) benzene-1,2-dicarboxylate. Molecular Weight: 390.6g/mol. Molecular Formula: C24H38O4;C6H4(COOC8H17)2;C24H38O4. SMILES: CCCCC (CC)COC (=O)C1=CC=CC=C1C (=O)OCC (CC)CCCC. InChI: InChI=1S/C24H38O4/c1-5-9-13-19(7-3)17-27-23(25)21-15-11-12-16-22(21)24(26)28-18-20(8-4)14-10-6-2/h11-12,15-16,19-20H,5-10,13-14,17-18H2,1-4H3. InChIKey: BJQHLKABXJIVAM-UHFFFAOYSA-N. Boiling Point: 723 °F at 760 mm Hg (NTP, 1992);384.0 ?;384 ?;385 ?;727°F;727°F. Melting Point: -58 °F (NTP, 1992);-55.0 ?;-55 ?;-50 ?;-58°F;-58°F. Flash Point: 405 °F (NTP, 1992);420 °F (215 ?) (Open cup);215 ? o.c.;420°F (open cup);(oc) 420°F. Density: 0.98 at 77 °F (USCG, 1999);0.981 g/cu cm at 25 ?;Relative density (water = 1): 0.986;0.99;0.99. Solubility: less than 0.1 mg/mL at 72° F (NTP, 1992);1.08e-07 M;In water, 2.70X10-1 mg/L at 25 ?;LESS THAN 0.01% IN WATER @ 25 ?;Soluble in blood and fluids containing lipoproteins;MISCIBLE WITH MINERAL OIL & HEXANE;Slightly soluble in carbon tetrachloride;Solubility in water: none;(75°F): 0.00003%. Viscosity: 22 cSt at 20 ?; 386 cSt at 0 ?; 5 cSt at 100 ?. | |
D-Thyroxine Quick inquiry Where to buy Suppliers range | D-Thyroxine is the dextrorotary isomer of thyroxine with antihyperlipidemic activity. It stimulates the formation of low-density lipoprotein (LDL) and increases the catabolism of LDL thereby leading to increased excretion of cholesterol and bile acids via the biliary route. It is released from thyroglobulin by proteolysis and secreted into the blood. It is one of the thyroid hormones involved in the maintenance of metabolic homeostasis and has been used to treat hyperlipidemia. It is used as an cholesterol-lowering drug but was pulled due to cardiac side-effects. It also increases hepatic lipase which in turn improves utilization of triglycerides, improving apolipoprotein E cholesterol particles. Uses: D-thyroxin is one of the thyroid hormones involved in the maintenance of metabolic homeostasis and has been used to treat hyperlipidemia. it is used as an cholesterol-lowering drug. Synonyms: Dextrothyroxine; Choloxin; Dextrothyroxinum; (R)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid; Biotirmone; Debetrol; D-T4; O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine. Grades: 95%. CAS No. 51-49-0. Molecular formula: C15H11I4NO4. Mole weight: 776.87. | |
Eprotirome Quick inquiry Where to buy Suppliers range | Eprotirome is a synthetic thyroid hormone mimetic as a thyroid hormone receptor beta agonists, lowers total and low-density lipoprotein cholesterol up to 40% without affecting high-density lipoprotein cholesterol levels and without deleterious side effects to the cardiovascular system. Uses: Thyroid hormone receptor beta agonists. Synonyms: KB-2115; KB 2115; KB2115; Eprotirome.3-[[3,5-dibromo-4-[4-hydroxy-3-(1-methylethyl)phenoxy]phenyl]amino-3-oxo-propanoic acid. Grades: ≥98%. CAS No. 355129-15-6. Molecular formula: C18H17Br2NO5. Mole weight: 487.14. | |
Evacetrapib Quick inquiry Where to buy Suppliers range | Evacetrapib (LY2484595) is a drug that inhibits cholesterylester transfer protein, which transfers and thereby increases high-density lipoprotein and lowers low-density lipoprotein. Synonyms: LY2484595; LY 2484595; LY-2484595. Grades: 0.98. CAS No. 1186486-62-3. Molecular formula: C31H36F6N6O2. Mole weight: 638.659. | |
Fenirofibrate O-b-D-glucuronide Quick inquiry Where to buy Suppliers range | Fenirofibrate O-b-D-glucuronide, a remarkable biomedicine, emerges as a key player in addressing dyslipidemia and hyperlipidemia-based afflictions. Acting as a derivative of fibrate, this innovative compound specifically targets the peroxisome proliferator-activated receptor alpha (PPAR-alpha). By skillfully modulating triglyceride levels and amplifying high-density lipoprotein (HDL) cholesterol levels, this medication showcases its unparalleled efficacy in rectifying lipid metabolism disorders. Synonyms: Fenirofibrate O-beta-D-Glucuronide; FENIROFIBRATE O-B-D-GLUCURONIDE; (2S,3S,4S,5R,6R)-6-[[4-(2-carboxypropan-2-yloxy)phenyl]-(4-chlorophenyl)methoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid; beta-D-Glucopyranosiduronic acid, [4-(1-carboxy-1-methylethoxy)phenyl](4-chlorophenyl)methyl; Fenirofibrate O-?-D-Glucuronide. CAS No. 168844-26-6. Molecular formula: C23H25ClO10. Mole weight: 496.90. | |
Fenofibrate Quick inquiry Where to buy Suppliers range | Antilipemic. It is a lipid regulating drug. Increases high density lipoprotein levels by reducing cholesteryl ester transfer protein expresion. Group: Biochemicals. Alternative Names: 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methyl-propanoic Acid 1-Methylethyl Ester;LF 178; Lipanthyl; Lipantil; Lipidil Supra; Lipirex; Lipoclar; Lipofene; Liposit; Lipsin; MeltDose; NSC 281319; Nolipax; Procetofen; Procetofene. Grades: Highly Purified. CAS No. 49562-28-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
Fenofibrate-d6 Quick inquiry Where to buy Suppliers range | Antilipemic. It is a lipid regulating drug. Increases high density lipoprotein levels by reducing cholesteryl ester transfer protein expresion. Group: Biochemicals. Alternative Names: 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methyl-propanoic Acid-d6 1-Methylethyl Ester;LF 178-d6; Lipanthyl-d6; Lipantil-d6; Lipidil Supra-d6; Lipirex-d6; Lipoclar-d6; Lipofene-d6; Liposit-d6; Lipsin-d6; MeltDose-d6; NSC 281319-d6; Nolipax-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Fenofibric Acid Quick inquiry Where to buy Suppliers range | Fenofibric Acid (Fenofibrate EP Impurity B; Fenofibrate USP Related Compound B) is the active metabolite of Fenofibrate (F248640). Increases Apolipoprotein A-I-Mediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptor-dependent manner. Group: Biochemicals. Alternative Names: 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methyl-propanoic Acid; FNF Acid; NSC 281318; Procetofenic Acid; Fenofibrate EP Impurity B; Fenofibrate USP Related Compound B. Grades: Highly Purified. CAS No. 42017-89-0. Pack Sizes: 1g, 5g. Molecular Formula: C??H??ClO?, Molecular Weight: 318.75. US Biological Life Sciences. | Worldwide |
FR-190809 Quick inquiry Where to buy Suppliers range | FR-190809 is a potent and orally efficacious ACAT inhibitor potentially for the treatment of Lipoprotein Disorders. Synonyms: 1-cycloheptyl-1-[[4-(4-fluorophenoxy)phenyl]methyl]-3-[6-methyl-2,4-bis(methylsulfonyl)pyridin-3-yl]urea; FR-190809; FR 190809; FR190809.N-cycloheptyl-N-(4-(4-fluorophenoxy)-benzyl)-N'-(2,4-bis(methylsulfonyl)-6-methylpyridin-3-yl)urea. Grades: >98%. CAS No. 215589-63-2. Molecular formula: C29H34FN3O6S2. Mole weight: 603.73. | |
FSL-1 Quick inquiry Where to buy Suppliers range | FSL 1 is a TLR2/6 peptide agonist (also a putative TLR10 ligand) that activates NF-κB. FSL 1 induces the expression of some pro-inflammatory cytokines such as IL-8, IL-1β, CCL20 and TNF-α in vitro. Synonyms: FSL 1; FSL1; L-Phenylalanine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-; S-[2,3-Bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine; FSL-1 lipoprotein, synthetic; Fibroblast-stimulating lipopeptide-1; Pam2-Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-OH. Grades: ≥95%. CAS No. 322455-70-9. Molecular formula: C84H140N14O18S. Mole weight: 1666.16. | |
FSL-1-FLAG Quick inquiry Where to buy Suppliers range | Lipopeptide FSL-1, synthesized on the basis of the N-terminal structure of M. salivarium lipoprotein, can induce ICAM-1 expression on the surface of human gingival fibroblasts. In addition, it induces the production of monocyte chemoattractant protein 1, interleukin-6 (IL-6), and IL-8. It activates macrophages to produce tumor necrosis factor-alpha. Synonyms: Fibroblast Stimulating Lipopeptide 1 FLAG-tag; H-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys-OH; L-Lysine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanyl-L-α-aspartyl-L-tyrosyl-L-lysyl-L-α-aspartyl-L-α-aspartyl-L-α-aspartyl-L-α-aspartyl-. Grades: ≥95%. CAS No. 2243206-97-3. Molecular formula: C125H198N24O37S. Mole weight: 2661.15. | |
FSL-1 TFA salt Quick inquiry Where to buy Suppliers range | FSL-1 is a TLR2/6 peptide agonist (also a putative TLR10 ligand) that activates NF-κB. FSL-1 induces the expression of some pro-inflammatory cytokines such as IL-8, IL-1β, CCL20 and TNF-α in vitro. Synonyms: FSL 1 TFA salt; FSL1 TFA salt; L-Phenylalanine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-, 2,2,2-trifluoroacetic acid; S-[2,3-Bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine 2,2,2-trifluoroacetic acid; FSL-1 lipoprotein, synthetic TFA salt; Fibroblast-stimulating lipopeptide-1 TFA salt; Pam2-Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-OH TFA. Grades: ≥95%. Molecular formula: C86H141F3N14O20S. Mole weight: 1780.18. | |
GSK 264220A Quick inquiry Where to buy Suppliers range | GSK 264220A is an endothelial lipase and lipoprotein lipase inhibitor (IC50 = 0.13 and 0.10 μM, respectively). Inhibition of endothelial lipase may lead to an increase in HDL levels and GSK 264220A is expected to be a therapy for cardiovascular disease. Uses: Potential treatment of cardiovascular disease. Synonyms: GSK-264220A; GSK 264220A; GSK264220A. N-[2-Methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenylurea; 3-[2-methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea; 1-(2-methyl-5-piperidin-1-ylsulfonylfuran-3-yl)-3-phenylurea. Grades: ≥98% by HPLC. CAS No. 685506-42-7. Molecular formula: C17H21N3O4S. Mole weight: 363.43. | |
Ikarugamycin Quick inquiry Where to buy Suppliers range | Ikarugamycin is an unsual pentacyclic tetramic acid produced by Streptomyces phaeochromogenes with potent activity against the protozoan, Trichomonas vaginalis, reported in 1972. Ikarugamycin also demonstrated selective Gram positive antibacterial activity and more recently has been shown to exhibit anti-ulcer activity possibly by inhibition of Helicobacter. Investigation of the pharmacology of ikarugamycin has demonstrated a variety of actions including the inhibition of the uptake of oxidized low-density lipoprotein in mouse macrophages, blockade of PMA and Nef-mediated cell surface CD4 down-regulation and inhibition of clathrin-coated pit-mediated endocytosis. Importantly, ikarugamycin is emerging as a useful. Group: Biochemicals. Grades: Highly Purified. CAS No. 36531-78-9. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
Ikarugamycin Quick inquiry Where to buy Suppliers range | An unusual pentacyclic tetramic acid produced by streptomyces phaeochromogenes; potent activity against the protozoan, trichomonas vaginalis; demonstrates selective gram positive antibacterial activity, and anti-ulcer activity possibly via inhibition of H. Pylori; inhibits the uptake of oxidized low-density lipoprotein in mouse macrophages, blocks PMA and nef-mediated cell surface CD4 down-regulation, and inhibits clathrin-coated pit-mediated endocytosis; a useful agent for studying the process of endocytosis. Synonyms: 14,17-Metheno-17H-as-indaceno[3,2-k][1,6]diazacycloheptadecine-9,16,18(1H)-trione. Grades: >99% by HPLC. CAS No. 36531-78-9. Molecular formula: C29H38N2O4. Mole weight: 478.62. | |
Lapaquistat acetate Quick inquiry Where to buy Suppliers range | Lapaquistat acetate, also referred as TAK475, is a squalene synthase inhibitor. As a cholesterol-lowering drug, Lapaquistat acetate decreased plasma cholesterol and triglyceride levels, by lowering lipoproteins containing apoB100. Uses: A novel squalene synthase inhibitor. Synonyms: 2-[1-[2-[(3R,5S)-1-(3-acetyloxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-5H-4,1-benzoxazepin-3-yl]acetyl]piperidin-4-yl]acetic acid; (1-(2-(1-(2-carboxyoxy-1,1-dimethylethyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydrobenzo(e)(1,4)oxazepin-3-yl)acetyl)piperidin-4-yl)acetic acid; 1-((1-(3-acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl)acetyl)piperidine-4-acetic acid; lapaquistat; TAK 475; TAK-475; TAK475. Grades: >98%. CAS No. 189060-13-7. Molecular formula: C33H41ClN2O9. Mole weight: 645.14. | |
Lathosterol Quick inquiry Where to buy Suppliers range | Lathosterol is an intermediate in the biosynthesis of cholesterol. Lathosterol in serum is carried on lipoproteins and is indicative of the rate of cholesterol synthesis. It acts as a marker of synthesis of cholesterol and is not affected by dietary consumption of cholesterol. Synonyms: 5alpha-Cholest-7-en-3beta-ol; Cholest-7-en-3-ol; 7-Cholesten-3-beta-ol. Grades: >99%. CAS No. 80-99-9. Molecular formula: C27H46O. Mole weight: 386.65. | |
L-Thyroxine sodium salt pentahydrate Quick inquiry Where to buy Suppliers range | L-Thyroxine sodium salt pentahydrate is an iodine containing hormone produced from thyroglobulin in the thyroid follicular cells. It reduces total cholesterol level, low-density lipoprotein cholesterol as well as waist to hip ratio in subclinical hypothyroidism pateints. It was also used to study the light-induced hormone conversion of T4 to T3 in regulation of photoperiodic response of gonads in Japanese quail. Synonyms: Sodium levothyroxine pentahydrate. Grades: >98%. CAS No. 6106-7-6. Molecular formula: C15H20I4NNaO9. Mole weight: 888.93. | |
MAC13243 Quick inquiry Where to buy Suppliers range | MAC13243, an antibacterial agent, is a likely inhibitor of the bacterial lipoprotein targeting chaperone, LolA. Synonyms: MAC13243 HCl; MAC 13243; MAC-13243; MAC13243 hydrochloride. Grades: >98%. CAS No. 1071638-38-4. Molecular formula: C20H25Cl2N3O2S. Mole weight: 442.4. | |
Naringenin Quick inquiry Where to buy Suppliers range | The aglucon of naringin. Naringenin is a flavonoid that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, anti-inflammatory, carbohydrate metabolism promoter, and immune system modulator. It is the predominant flavanone in grapefruit. This substance has also been shown to reduce oxidative damage to DNA in vitro. Scientists exposed cells to 80 micromoles of naringenin per liter, for 24 hours, and found that the amount of hydroxyl damage to the DNA was reduced by 24% in that very short period of time.Naringenin found in grapefruit juice has been shown to have an inhibitory effect on the human cytochrome P450 isoform CYP1A2, which can change pharmacokinetics in a human (or orthologous) host of several popular drugs in an adverse manner, even resulting in carcinogens of otherwise harmless substances.Naringenin has also been shown to reduce hepatitis C virus production by infected hepatocytes (liver cells) in cell culture. This seem to be secondary to Naringenin ability to inhibit the secretion of very-low-density lipoprotein by the cells.Naringenin seems to protect LDLR-deficient mice from the obesity effects of a high-fat diet.Naringenin lowers the plasma and hepatic cholesterol concentrations by suppressing HMG-CoA reductase and ACAT in rats fed a high-cholesterol diet. Group: Biochemicals. Alternative Names: 2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; (R,S)-Naringenin; (+/-)-5,7,4-Trihydroxyflavanone; 5,7,4-Trihydroxyflavanone. Grades: Highly Purified. CAS No. 67604-48-2. Pack Sizes: 10g. Molecular Formula: C??H??O?, Molecular Weight: 272.25. US Biological Life Sciences. | Worldwide |
NO-1886 Quick inquiry Where to buy Suppliers range | NO-1886 is a lipoprotein lipase (LPL) activator that increases the level of high-density lipoprotein cholesterol and reduces plasma triglycerides. It was shown to prevent fat accumulation in high fat-fed rats, suggesting its potential use as an antidiabetic agent. Synonyms: Ibrolipim; Lipoprotein Lipase Activator; LPL Activator; OPF 009; N-(4-bromo-2-cyanophenyl)-4-(diethoxyphosphorylmethyl)benzamide. Grades: ≥98%. CAS No. 133208-93-2. Molecular formula: C19H20BrN2O4P. Mole weight: 451.3. | |
Pam3CSK4 Biotin Quick inquiry Where to buy Suppliers range | Pam3CSK4 Biotin is the biotinylated Pam3CSK4. Pam3CSK4 is a synthetic tripalmitoylated lipopeptide that mimicks the acylated amino terminus of bacterial lipoproteins. Pam3CSK4 is a potent activator of the proinflammatory transcription factor NF-κB and a toll-like receptor 1/2 (TLR1/2) agonist. It stimulates phosphorylation of p100/p110 and p60 in granulocytic-differentiated HL-60 cells, and promotes differentiation of naive CD4+ T cells into Th17 cells. Synonyms: (2S, 3Z, 5S, 6Z, 8S, 9Z, 11S, 12Z, 14S, 15Z, 17R)-5, 8, 11-tris(4-aminobutyl)-4, 7, 10, 13, 16-pentahydroxy-2-(4-((Z)-(1-hydroxy-6-((Z)-(1-hydroxy-6-((Z)-(1-hydroxy-5-((3aR, 6S, 6aS)-2-hydroxy-3a, 4, 6, 6a-tetrahydro-1H-thieno[3, 4-d]imidazol-6-yl)pentylidene)amino)hexylidene); Pam3CysSerLys4. Grades: ≥95%. CAS No. 1429504-10-8. Molecular formula: C103H192N14O17S2. Mole weight: 1962.85. | |
Pam3Cys-Ser-(Lys)4 3HCl (Pam3CSK4, Pam3Cys-SKKKK, (S)-[2,3-Bis(palmitoyloxy)-(2-RS)-propyl]-N-palmitoyl-(R)-Cys-(S)-Ser-(S)-Lys4-OH) Quick inquiry Where to buy Suppliers range | Selective agonist of TLR1/TLR2 complex. Cell permeable, water soluble synthetic cationic lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein that potently activates monocytes and macrophages. Potent and effective immune adjuvant. Exerts strong local response, enhances IgG2a and IgG1 titers and upregulates proinflammatory and Th1 cytokine genes. Potent activator of the proinflammatory transcription factor NF-kappaB. Activates/represses at least 140 genes involved in signal transduction and regulation of the immune response. Group: Biochemicals. Alternative Names: Pam3CSK4, Pam3Cys-SKKKK, (S)-[2,3-Bis(palmitoyloxy)-(2-RS)-propyl]-N-palmitoyl-(R)-Cys-(S)-Ser-(S)-Lys4-OH. Grades: Highly Purified. CAS No. 112208-00-1. Pack Sizes: 2mg. US Biological Life Sciences. | Worldwide |
Phosphocholine Chloride Calcium Salt Tetrahydrate Quick inquiry Where to buy Suppliers range | Phosphocholine Chloride is a specific promoter of heparin and serum β-lipoprotein interaction. Phosphocholine Chloride protects the membranes of platelets, erythrocytes, and lysosomes against the labilizing action of various known membrane labilizers. Group: Biochemicals. Alternative Names: N, N, N-Trimethyl-2- (phosphonooxy) ethanaminium Chloride Calcium Salt Tetrahydrate; Biocalcose Tetrahydrate; Calcium Phosphorylcholine Tetrahydrate; Calcium phosphorylcholine Chloride Tetrahydrate; Colifos Tetrahydrate; Colincalcium Tetrahydrate; Epafosforil Tetrahydrate; Fosfocolina Tetrahydrate; Ipercolin Tetrahydrate; Isocolin Tetrahydrate; Mebophos Tetrahydrate; Merival Tetrahydrate; Pancholin Tetrahydrate; Phoscholin Tetrahydrate. Grades: Highly Purified. CAS No. 72556-74-2. Pack Sizes: 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
Pitavastatin 3-Oxo Ethyl Ester Quick inquiry Where to buy Suppliers range | A metabolite of Pitavastatin which lowers both total cholesterol and low density lipoprotein cholesterol in animals and humans. Synonyms: (E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Ethyl Ester. Grades: > 95%. CAS No. 148901-69-3. Molecular formula: C27H26FNO4. Mole weight: 447.51. | |
Pitavastatin Impurity 18 Quick inquiry Where to buy Suppliers range | An impurity of Pitavastatin which lowers both total cholesterol and low density lipoprotein cholesterol in animals and humans. Synonyms: Pitavastatin N-Oxide. Grades: > 95%. Molecular formula: C25H24FNO5. Mole weight: 437.47. | |
Pitavastatin Impurity 8 Quick inquiry Where to buy Suppliers range | An impurity of Pitavastatin which lowers both total cholesterol and low density lipoprotein cholesterol in animals and humans. Synonyms: 3,5-Dideoxy-2,4-O-(1-methylethylidene)-D-erythro-hexuronic Acid 1,1-Dimethylethyl Ester. Grades: > 95%. CAS No. 1044518-75-3. Molecular formula: C13H22O5. Mole weight: 258.32. | |
Pravastatin Quick inquiry Where to buy Suppliers range | Pravastatin is an antilipemic fungal metabolite isolated from cultures of Nocardia autotrophica. It acts as a competitive inhibitor of HMG CoA reductase with IC50 of 5.6 μM. It is used in combination with diet, exercise, and weight loss for lowering cholesterol and preventing cardiovascular disease. It is a synthetic lipid-lowering agent. It lowers plasma cholesterol and lipoprotein levels, and modulates immune responses by suppressing major histocompatibility complex II on interferon gamma-stimulated, antigen-presenting cells such as human vascular endothelial cells. It is primarily used for the treatment of dyslipidemia and the prevention of cardiovascular disease. It is used to reduce LDL cholesterol and triglyceride levels and increase HDL cholesterol in the prevention of cardiovascular disease. Uses: Pravastatin acts as a competitive inhibitor of hmg coa reductase. it is a synthetic lipid-lowering agent. it is primarily used for the treatment of dyslipidemia and the prevention of cardiovascular disease. it is used to reduce ldl cholesterol and triglyceride levels and increase hdl cholesterol in the prevention of cardiovascular disease. Synonyms: 1-Naphthaleneheptanoicacid, 1, 2, 6, 7, 8, 8a-hexahydro-b, d, 6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-, [1S-[1a(bS*, dS*), 2a, 6a, 8b(R*), 8aa]]-; 3b-Hydroxycompactin; Eptastatin; Mevalothin; Pravastatin acid;Pravachol; Pravastatina; Pravastatine; Pravastatinum; (3R, 5R)-7-[(1S, 2S, 6S, 8S, 8aR)-6-hydroxy-2-methyl-8-[(2S)-2-methylbutanoyl]oxy-1, 2, 6, 7, 8, 8a-hexahydronaphthalen-1-yl]-3, 5-dihydroxyheptanoic acid. Grades: 98%. CAS No. 81093-37-0. Molecular formula: C23H36O7. Mole weight: 424.53. | |
PX 102 Quick inquiry Where to buy Suppliers range | PX102 is a Farnesoid X-activated Receptor (FXR) agonist originated by Phenex Pharmaceuticals. PX102 demonstrated potent plasma cholesterol-lowering activity that affected all lipoprotein species. But treatment for Metabolic syndrome and Non-alcoholic steatohepatitis were discontinued. Uses: Metabolic syndrome; non-alcoholic steatohepatitis. Synonyms: PX 102; PX102; PX-102; UNII-378SU5NO8S; 378SU5NO8S; SCHEMBL17087854; Px-102; PX20606; 4- [ (1S, 2S) -2- [2-chloro-4- [ [5-cyclopropyl-3- (2, 6-dichlorophenyl) -1, 2-oxazol-4-yl] methoxy] phenyl] cyclopropyl] benzoic acid. Grades: 98%. CAS No. 1268245-19-7. Molecular formula: C29H22Cl3NO4. Mole weight: 554.85. | |
Rilapladib Quick inquiry Where to buy Suppliers range | Rilapladib is the third genomics-derived small molecule drug as a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor which is an enzyme associated with the formation of atherosclerotic plaques. Uses: 1-alkyl-2-acetylglycerophosphocholine esterase inhibitors. Synonyms: GSK 659032; GSK659032; GSK-659032; SB-659032; SB659032; SB 659032; GTPL7376; GTPL-7376; GTPL 7376; D05728. Grades: ≥98%. CAS No. 412950-08-4. Molecular formula: C40H38F5N3O3S. Mole weight: 735.81. | |
R-IMPP Quick inquiry Where to buy Suppliers range | R-IMPP is an inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9). PCSK9 is a regulator of low-density lipoprotein cholesterol (LDL-C), which is related to the risk of atherosclerosis and other cardiovascular disorders. Uses: An inhibitor of proprotein convertase subtilisin/kexin type 9 (pcsk9). Synonyms: RIMPP; R IMPP; (R)-IMPP; (R)-N-(isoquinolin-1-yl)-3-(4-methoxyphenyl)-N-(piperidin-3-yl)propanamide. CAS No. 2133832-83-2. Molecular formula: C24H27N3O2. Mole weight: 389.50. | |
SB 204990 Quick inquiry Where to buy Suppliers range | SB 204990 is a prodrug of SB 201076, which is an ATP citrate lyase (ACLY) inhibitor. SB 204990 inhibits cholesterol and fatty acid synthesis in a dose-dependent manner in HepG2 cells. SB 204990 was shown to decrease plasma levels of the lipoproteins VLDL, LDL, and HDL in dogs. Synonyms: SB-204990; SB 204990; SB204990; (3R,5S)-rel-5-[6-(2,4-Dichlorophenyl)hexyl]tetrahydro-3-hydroxy-2-oxo-3-furanacetic acid. Grades: ≥98% by HPLC. CAS No. 154566-12-8. Molecular formula: C18H22Cl2O5. Mole weight: 389.27. | |
SB-253514 Quick inquiry Where to buy Suppliers range | SB-253514 is an inhibitor of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579. Synonyms: SB 253514; SB253514. Molecular formula: C28H46N2O9. Mole weight: 554.7. | |
SB-311009 Quick inquiry Where to buy Suppliers range | SB-311009 is an inhibitor of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579. Synonyms: SB 311009; SB311009. Molecular formula: C22H36N2O5. Mole weight: 408.5. | |
SB-315021 Quick inquiry Where to buy Suppliers range | SB-315021 is an inhibitor of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579. Synonyms: SB 315021; SB315021. Molecular formula: C28H46N2O9. Mole weight: 554.7. | |
Stachybotramide Quick inquiry Where to buy Suppliers range | Stachybotramide is produced by the mycelia and culture broth of Stachybotrys sp. Stachybotramide can stimulate the plasma cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters (CE) from high density lipoprotein (HDL) to very low density lipoprotein (VLDL) and low density lipoprotein (LDL). Synonyms: Spirodihydrobenzofuranlactam II; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one, 3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-, (1'R,2'R,4'aS,6'R,8'aS)-; (1'R,2'R,4'aS,6'R,8'aS)-3',4',4'a,5',6',7,7',8,8',8'a-Decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethylspiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one; Stachybotrin; Spiro[2H-furo[2,3-e]isoindole-2,1'(2'H)-naphthalen]-6(3H)-one, 3',4',4'a,5',6',7,7',8,8',8'a-decahydro-4,6'-dihydroxy-7-(2-hydroxyethyl)-2',5',5',8'a-tetramethyl-, [1'R-(1'α, 2'α, 4'aα, 6'α, 8'aβ)]-. Grades: 97.5%. CAS No. 149598-71-0. Molecular formula: C25H35NO5. Mole weight: 429.55. | |
T0901317 Quick inquiry Where to buy Suppliers range | T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively. T0901317 induces apoptosis and inhibits the development of atherosclerosis in low-density lipoprotein (LDL) receptor-deficient mice. Synonyms: T 0901317; T-0901317; TO-901317; TO901317; N- (2, 2, 2-trifluoroethyl) -N-[4-[2, 2, 2-trifluoro-1-hydroxy-1- (trifluoromethyl) ethyl]phenyl]benzenesulfonamide; T-1317. Grades: >98%. CAS No. 293754-55-9. Molecular formula: C17H12F9NO3S. Mole weight: 481.33. | |
Tiliroside Quick inquiry Where to buy Suppliers range | A naturally occurring flavonoid that shows anti-complement, anti-inflammatory and free radical scavenger activity. Inhibits the production of the inflammatory mediators nitric oxide (NO), TNF-a and IL-12 in activated macrophages. Also inhibits human Low Density Lipoprotein (LDL) oxidation. Group: Biochemicals. Grades: Highly Purified. CAS No. 10238-21-8. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
TMC-49A Quick inquiry Where to buy Suppliers range | TMC-49A is a transcriptional up-regulator of low density lipoprotein receptor. It is produced by Streptomyces sp. AS1345. It enhanced the synthesis of LDL receptor in human hepatoma HepG2 cells as assessed by a receptor binding assay. Synonyms: TMC-49 A; 2-phenylethyl n-butyl carbamate. Molecular formula: C13H19NO2. Mole weight: 221.29. | |
Torcetrapib Quick inquiry Where to buy Suppliers range | Torcetrapib is a Cholesteryl ester transfer protein (CETP) inhibitor. CETP normally transfers cholesterol from HDL cholesterol to very low density or low density lipoproteins (VLDL or LDL). Inhibition of this process results in higher HDL levels (the "good" cholesterol-containing particle) and reduces LDL levels (the "bad" cholesterol). Unfortunately clinical trials were stopped because of excessive all cause mortality. Reasons are still being investigated, but may be related to some off target effects such as an increase in aldosterone secretion not found in some other CETP inhibitors. Uses: Anticholesteremic agents. Synonyms: CP-529414; CP 529414; CP529414. Grades: >98%. CAS No. 262352-17-0. Molecular formula: C26H25F9N2O4. Mole weight: 600.47. | |
Tyloxapol, USP Quick inquiry Where to buy Suppliers range | Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. It is used as a surfactant to aid liquefaction and removal of mucopurulent[citation needed] (containing mucus and pus) bronchopulmonary secretions,[1][2] administered by inhalation through a nebulizer[3] or with a stream of oxygen. With intraperitoneal injection, tyloxapol also blocks plasma lipolytic activity, and thus the breakdown of triglyceride-rich lipoproteins. This mechanism is used to induce experimental hyperlipidemia in animals.[4] Tyloxapol is the main active ingredient of the medical device Tacholiquin®. Tacholiquin® is an expectorant designated for inhalation and instillation reaching the upper and lower airways. Group: Biochemicals. Alternative Names: p- (1, 1, 3, 3-Tetramethylbutyl) Phenol Polymer with Ethylene Oxide and Formaldehyde; Ethylene Oxide Polymer with Formaldehyde and p- (1, 1, 3, 3-Tetramethylbutyl) phenol; Oxirane Polymer with Formaldehyde and 4- (1, 1, 3, 3-tetramethylbutyl) phenol; Ethylene oxide-formaldehyde-4- (1, 1, 3, 3-tetramethylbutyl) phenol copolymer; Ethylene oxide-formaldehyde-p-octylphenol Copolymer; NSC 90255; Superinone; Triton A 20; Triton WR 1339; Tyloxapol; p-Isooctyl polyoxyethyl ene phenol Formaldehyde Polymer. Grades: USP. CAS No. 25301-02-4. Pack Sizes: 1g, 5g, 25g. Molecular Formula: (C17H30O4)n, Molecular Weight: As reported. US Biological Life Sciences. | Worldwide |