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| Product | Description | |
|---|---|---|
| lipoprotein lipase | Hydrolyses triacylglycerols in chylomicrons and low-density lipoproteins. Also hydrolyses diacylglycerol. Group: Enzymes. Synonyms: clearing factor lipase; diglyceride lipase; diacylglycerol lipase; postheparin esterase; diglyceride lipase; postheparin lipase; diacylglycerol hydrolase; lipemia-clearing factor. Enzyme Commission Number: EC 3.1.1.34. CAS No. 9004-2-8. LPL. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3460; lipoprotein lipase; EC 3.1.1.34; 9004-02-8; clearing factor lipase; diglyceride lipase; diacylglycerol lipase; postheparin esterase; diglyceride lipase; postheparin lipase; diacylglycerol hydrolase; lipemia-clearing factor. Cat No: EXWM-3460. |  |
| Chemically modified Pseudomonas species Lipoprotein Lipase | Enzyme that hydrolyzes triglycerides into three free fatty acids and glycerol. Take advantage of the enhanced liquid stability of this enzyme. Rely on the proven diagnostic quality of this product. Applications: Use lipoprotein lipase in diagnostic tests for the determination of triglycerides together with glycerol kinase and glycerol-3-phosphate dehydrogenase. Group: Enzymes. Synonyms: Lipoprotein lipase; LPL; Clearing factor lipase; Diacylglycerol lipase; Diglyceride lipase. LPL. Mole weight: 47 kD. Activity: >10 U/mg lyophilizate. Stability: At +2 to +8°C within specification range for 12 months. Store dry. Appearance: Brownish lyophilizate. Source: Pseudomonas species. Lipoprotein lipase; LPL; EC 3.1.1.34; Clearing factor lipase; Diacylglycerol lipase; Diglyceride lipase. Cat No: DIA-282. | |
| low-density-lipoprotein receptor kinase | Phosphorylates the last serine residue (Ser-833) in the cytoplasmic domain of the low-density lipoprotein receptor from bovine adrenal cortex. Casein can also act as a substrate but with lower affinity. GTP can act instead of ATP. Group: Enzymes. Synonyms: ATP:low-density-lipoprotein-L-serine O-phosphotransferase; LDL receptor kinase; [low-density-lipoprotein] kinase; low-density lipoprotein kinase; low-density-lipoprotein receptor kinase (phosphorylating); STK7. Enzyme Commission Number: EC 2.7.11.29. CAS No. 107445-00-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3149; low-density-lipoprotein receptor kinase; EC 2.7.11.29; 107445-00-1; ATP:low-density-lipoprotein-L-serine O-phosphotransferase; LDL receptor kinase; [low-density-lipoprotein] kinase; low-density lipoprotein kinase; low-density-lipoprotein receptor kinase (phosphorylating); STK7. Cat No: EXWM-3149. | |
| Native Bovine Lipoprotein Lipase | Lipoprotein lipase (LPL) (EC 3.1.1.34) is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase. It is a water-soluble enzyme that hydrolyzes triglycerides in lipoproteins, such as those found in chylomicrons and very low-density lipoproteins (VLDL), into two free fatty acids and one monoacylglycerol molecule. It is also involved in promoting the cellular uptake of chylomicron remnants, cholesterol-rich lipoproteins, and free fatty acids. LPL requires ApoC-II as a cofactor. LPL is attached to the luminal surface of endothelial cells in capillaries by the protein glycosylphosphatidylinositol HDL-binding protein 1 (GPIHBP1) and by heparin sulfated proteoglycans. It is most widely distributed in adipose, heart, and skeletal muscle tissue, as well as in lactating mammary glands. Group: Enzymes. Synony. Enzyme Commission Number: EC 3.1.1.34. CAS No. 9004-2-8. LPL. Activity: > 2,000 units/mg protein (BCA). Storage: 2-8°C. Form: ammonium sulfate suspension; Suspension in 3.8 M ammonium sulfate, 0.02 M Tris HCl, pH 8.0. Source: Bovine milk. Species: Bovine. lipoprotein lipase; clearing factor lipase; diglyceride lipase; diacylglycerol lipase; postheparin esterase; diglyceride lipase; postheparin lipase; diacylglycerol hydrolase; lipemia-clearing factor; EC 3.1.1.34; 9004-02-8; LPL. Cat No: NATE-0416. | |
| Native Burkholderia sp. Lipoprotein Lipase | Lipoprotein lipase (LPL) (EC 3.1.1.34) is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase. It is a water-soluble enzyme that hydrolyzes triglycerides in lipoproteins, such as those found in chylomicrons and very low-density lipoproteins (VLDL), into two free fatty acids and one monoacylglycerol molecule. It is also involved in promoting the cellular uptake of chylomicron remnants, cholesterol-rich lipoproteins, and free fatty acids. LPL requires ApoC-II as a cofactor. LPL is attached to the luminal surface of endothelial cells in capillaries by the protein glycosylphosphatidylinositol HDL-binding protein 1 (GPI...rin in rats. Group: Enzymes. Synonyms: lipoprotein lipase; clearing factor lipase; diglyceride lipase; diacylglycerol lipase; postheparin esterase; diglyceride lipase; postheparin lipase; diacylglycerol hydrolase; lipemia-clearing factor; EC 3.1.1.34; 9004-02-8; LPL. Enzyme Commission Number: EC 3.1.1.34. CAS No. 9004-2-8. LPL. Activity: > 50,000 units/mg solid. Storage: -20°C. Form: lyophilized powder. Source: Burkholderia sp. lipoprotein lipase; clearing factor lipase; diglyceride lipase; diacylglycerol lipase; postheparin esterase; diglyceride lipase; postheparin lipase; diacylglycerol hydrolase; lipemia-clearing factor; EC 3.1.1.34; 9004-02-8; LPL. Cat No: NATE-0417. | |
| Native Microorganism Lipoprotein lipase | Lipoprotein lipase (LPL) (EC 3.1.1.34) is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase. It is a water soluble enzyme that hydrolyzes triglycerides in lipoproteins, such as those found in chylomicrons and very low-density lipoproteins (VLDL), into two free fatty acids and one monoacylglycerol molecule. It is also involved in promoting the cellular uptake of chylomicron remnants, cholesterol-rich lipoproteins, and free fatty acids. LPL requires ApoC-II as a cofactor. Applications: This enzyme is useful for enzymatic determination of triglyceride in serum when coupled with l-α-glycerophosphate oxidase and glycerol kinase. usually, the reaction can be completed in 5 minutes at 37°c by using 2.5~3.0 units of the enzyme per test (3.0ml) at ph around 7.0. Group: Enzymes. Synonyms: Lipoprotein lipase; LPL; EC 3.1.1.34; Clearing factor lipase; Diacylglycerol lipase; Diglyceride lipase. Enzyme Commission Number: EC 3.1.1.34. CAS No. 9004-2-8. LPL. Activity: Grade??1.0U/mg-solid or more. Stability: Store at -20°C. Appearance: Light brown amorphous powder, lyophilized. Source: Microorganism. Lipoprotein lipase; LPL; EC 3.1.1.34; Clearing factor lipase; Diacylglycerol lipase; Diglyceride lipase. Cat No: DIA-211. | |
| Native Pseudomonas sp. Lipoprotein lipase | Lipoprotein lipase (LPL) (EC 3.1.1.34) is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase. It is a water soluble enzyme that hydrolyzes triglycerides in lipoproteins, such as those found in chylomicrons and very low-density lipoproteins (VLDL), into two free fatty acids and one monoacylglycerol molecule. It is also involved in promoting the cellular uptake of chylomicron remnants, cholesterol-rich lipoproteins, and free fatty acids. LPL requires ApoC-II as a cofactor. Applications: This enzyme is useful for enzymatic determination of triglyceride in serum when coupled with l-α-glycerophosphate oxidase and glycerol kinase. usually, the reaction can be completed in 5 minutes at 37°c by using 2.5~3.0 units of the enzyme per test (3.0ml) at ph around 7.0. Group: Enzymes. Synonyms: Lipoprotein lipase; LPL; EC 3.1.1.34; Clearing factor lipase; Diacylglycerol lipas. Enzyme Commission Number: EC 3.1.1.34. CAS No. 9004-2-8. LPL. Mole weight: approx. 134 kDa. Activity: Grade??20U/mg-solid or more (containing approx. 80% of stabilizers). Stability: Stable at-20°C for at least one year. Appearance: Light brown amorphous powder, lyophilized. Source: Pseudomonas sp. Lipoprotein lipase; LPL; EC 3.1.1.34; Clearing factor lipase; Diacylglycerol lipase; Diglyceride lipase. Cat No: DIA-210. | |
| 1,2-Dioleoyl-sn-glycerol | ALN29882 is a glycerolipid located on the plasma membrane. It consists of two fatty acid chains covalently linked to a single glycerol molecule by means of an ester bond. 18:1 DG has been used as a source of diacylglycerol in the diacylglycerol O-acyltransferase 1 (DGAT1) assay. It is also used as a substrate in the DGAT-1 enzyme assay to evaluate compounds as potential inhibitors of DGAT-1. Suitable for lipoprotein overlay screening assays with the recombinant protein His-AtROP6. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: sn-1,2-Dioleoylglycerol. CAS No. 24529-88-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-141572. |  |
| 1-Myristoyl-sn-glycero-3-phosphocholine | 1-Myristoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine derivative, which is found in plasma and oxidized low-density lipoprotein (Ox-LDL). It can be used as a biomarker for detecting lipid metabolism. Synonyms: 3-sn-Lysophosphatidylcholine; lysomyristoyl phosphatidylcholine; Lysolecithin,tetradecanoyl; 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphatidylcholine; M-lyso-PC; 1-Tetradecanoyl-sn-glycero-3-phosphocholine; (7R)-,7-Dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphatricosan-1-aminium Inner salt 4-Oxide; (R)-,7-Dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphatricosan-1-aminium Inner salt 4-Oxide; 1-Myristoyl-L-α-phosphorylcholine; 1-Tetradecanoyl-sn-glycero-3-phosphorylcholine; L-α-Myristoyllysophosphatidylcholine; M-LysoPC; Myristoyl L-α-lysolecithin; Myristoyl L-α-Lysophosphatidylcholine; LPC(14:0); LyPC(14:0); PC(14:0/0:0). Grades: >99% by HPLC. CAS No. 20559-16-4. Molecular formula: C22H46NO7P. Mole weight: 467.58. |  |
| 1-Palmitoyl-2-[3- (diphenylhexatriene) propanoyl]-sn-phosphatidylcholine-d9 | 1-Palmitoyl-2-[3- (diphenylhexatriene) propanoyl]-sn-phosphatidylcholine-d9 is labelled 1-Palmitoyl-2-[3- (diphenylhexatriene) propanoyl]-sn-phosphatidylcholine (P156600) which is a phosphatidylcholine containing fluorescent probe used in the the continuous determination of surface lipid oxidation of lipoproteins and plasma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C45H59D9NO8P, Molecular Weight: 791.05. US Biological Life Sciences. |  Worldwide |
| 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methyl-N-(1-methylethyl)-propanamide | 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methyl-N-(1-methylethyl)-propanamide is an intermediate in synthesizing Fenofibric Acid 1,1-Dimethyl-2-(1-methylethoxy)-2-oxoethyl Ester (F248680), which is an impurity of Febofibrate (F248640). Febofibrate is an antilipemic. It is a lipid regulating drug. Increases high density lipoprotein levels by reducing cholesteryl ester transfer protein expresion. Group: Biochemicals. Grades: Highly Purified. CAS No. 1316847-19-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C20H22ClNO3. US Biological Life Sciences. | Worldwide |
| 2-(N-Ethyl-m-toluidino)ethanol | A 2-(N-Ethyl-m-toluidino)ethanol pigment system and lipoprotein lipase are used as a new glycerol oxidase determination method for serum triglyceride. 2-(N-Ethyl-m-toluidino)ethanol is also used in quantitative structure-activity relationship (QSAR) models that are developed to predict the aquatic toxicity of chemicals to the fathead minnow (Pimephales promelas). Group: Biochemicals. Grades: Highly Purified. CAS No. 91-88-3. Pack Sizes: 2.5g, 10g. Molecular Formula: C11H17NO, Molecular Weight: 179.26. US Biological Life Sciences. | Worldwide |
| 3,5-Dichloro-2-hydroxybenzenesulfonic acid, sodium salt (HDCBS-Na) | Chromogenic reagent for HDL cholesterol. HDL (High Density Lipoproteins) are responsible for the reverse transport of cholesterol from peripheral cells to the liver, where cholesterol is transformed to bile acids. These are excreted into the intestine via the biliary tract. Monitoring of HDL-cholesterol in serum is of clinical importance because there is an inverse correlation between serum HDL-cholesterol concentrations and the risk of atherosclerotic disease. It is believed that elevated HDL-cholesterol concentrations offer protection against coronary heart disease, while reduced HDL-cholesterol concentrations, particularly in conjunction with elevated triglycerides, increase cardiovascular risk. Group: Biochemicals. Grades: Highly Purified. CAS No. 54970-72-8. Pack Sizes: 50g, 100g. US Biological Life Sciences. | Worldwide |
| 3-Chloro-L-tyrosine | 3-Chloro-L-tyrosine is a specific marker of myeloperoxidase-catalyzed oxidation, and is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. Uses: Scientific research. Group: Natural products. Alternative Names: 3-Chlorotyrosine. CAS No. 7423-93-0. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g. Product ID: HY-W041171. | |
| 3'-Cholesterol CPG 1000 | 3'-Cholesterol CPG 1000 is a highly sought-after phosphoramidite building block, coveted by experts in the field for its impressive versatility and usefulness. Boasting numerous applications within the biomedical industry, its primary function is in the synthesis of oligonucleotides with cholesterol conjugates. Scientists and researchers alike utilize this remarkable product in their study of lipoprotein metabolism, and its effectiveness in the treatment of hypercholesterolemia-associated diseases such as atherosclerosis cannot be overstated. | |
| 3'-Cholesteryl-frits column (100nmol) | 3'-Cholesteryl-frits column (100nmol) represents a sophisticated stationary phase utilized for liquid chromatography, that accurately separates and purifies cholesterol-containing molecules in diverse biological samples. The multifunctional and versatile column enables a comprehensive examination of lipoprotein composition, the diagnosis of lipid metabolism disorders, and offers a profound scope for developing therapeutic agents to combat cardiovascular diseases. Synonyms: 3'-Cholesteryl-frits column. | |
| 4-Chloro-4-hydroxybenzophenone | The impurity of Fenofibric acid (42017-89-0), the active metabolite of fenofibrate which increases Apolipoprotein A-I-Mediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptor-dependent manner. Group: Biochemicals. Alternative Names: (4-Chlorophenyl) (4-hydroxyphenyl) methanone; 4-(4-chlorobenzoyl)phenol. Grades: Highly Purified. CAS No. 42019-78-3. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 5-Methyltetrahydrofolic acid | 5-Methyltetrahydrofolic acid (5-Methyl THF) is the main circulating form of folic acid in the body and is involved in a variety of biochemical reactions. 5-Methyltetrahydrofolic acid regulates cardiovascular function by increasing the production of endothelin-1 (ET-1) in low-density lipoprotein-treated endothelial cells and can be used in the study of cardiovascular diseases [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: 5-Methyl THF; 5-MTHF. CAS No. 134-35-0. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-113046. | |
| Acaterin | Acarbose is an acyl-CoA isolated from Pseudomonas species. A92. In the presence of oxidized low-density lipoprotein in macrophages J744, the synthesis of cholesterol enzymes is inhibited, with an IC50 of 45 μmol/L, and the IC50 for inhibiting ACAT in rat liver microsomes is 120 μmol/L. Inhibition of ACAT is non-competitive Sexual. Synonyms: (2R)-4-[(1R)-1-hydroxyoctyl]-2-methyl-2H-furan-5-one; 3-(1-Hydroxyoctyl)-5-methyl-2(5H)-furanone. Grades: >98%. CAS No. 144398-20-9. Molecular formula: C13H22O3. Mole weight: 226.31. | |
| Acetoacetic acid sodium | Acetoacetic acid sodium is a metabolite of non-esterified fatty acids, involved in the development of human diabetes. Acetoacetic acid sodium induces oxidative stress to inhibit the assembly of very low density lipoprotein in bovine hepatocytes [1]. Uses: Scientific research. Group: Natural products. CAS No. 623-58-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112540B. | |
| acetylalkylglycerol acetylhydrolase | Hydrolysis of the acetyl group from the 1-alkyl-2-acetyl and 1-alkyl-3-acetyl substrates occurs at apparently identical rates. The enzyme from Erlich ascites cells is membrane-bound. It differs from lipoprotein lipase (EC 3.1.1.34) since 1,2-diacetyl-sn-glycerols are not substrates. It also differs from EC 3.1.1.47, 1-acetyl-2-alkyl-glycerophosphocholine esterase. Group: Enzymes. Synonyms: alkylacetylglycerol acetylhydrolase. Enzyme Commission Number: EC 3.1.1.71. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3499; acetylalkylglycerol acetylhydrolase; EC 3.1.1.71; alkylacetylglycerol acetylhydrolase. Cat No: EXWM-3499. | |
| Acetyl-Coenzyme A acetyltransferase 2 from Human, Recombinant | ACAT2 enzyme participates in lipid metabolism. ACAT2 takes part in lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. ACAT2 is an integral membrane protein that localizes to the endoplasmic reticulum of human intestinal cells. ACAT2 deficiency contributes to severe mental retardation and hypotonus. Acat2 recombinant human produced in e. coli is a single, non-glycosylated polypeptide chain containing 433 amino acids (1-397 a.a.) and having a molecular mass of 45.4 kda. the acat2 is fused to 36 amino acid his-tag at n-terminus and purified by proprietary chromatographic techniques. Group: Enzymes. Synonyms: Acetyl-CoA acetyltransferase cytosolic; Cytosolic acetoacetyl-CoA thiolase; ACAT2; Acetyl CoA transferase-like protein; ACAT-2. Purity: Greater than 95.0% as determined by SDS-PAGE. ACAT-2. Mole weight: 45.4 kDa. Stability: ACAT2 Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles. Appearance: Sterile Filtered clear solution. Source: E. coli. Species: Human. Acetyl-CoA acetyltransferase cytosolic; Cytosolic acetoacetyl-CoA thiolase; ACAT2; Acetyl CoA transferase-like protein; ACAT-2. Cat No: NATE-0798. | |
| ANG1005 | ANG1005 (Paclitaxel trevatide) is a brain-penetrating peptide-drug conjugate. ANG1005, a taxane derivative, consists of three paclitaxel (HY-B0015) molecules covalently linked to Angiopep-2, designed to cross the blood-brain and blood-cerebrospinal barriers and to penetrate malignant cells via low density lipoprotein receptor-related protein (LRP1) transport system [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: GRN1005; Paclitaxel trevatide. CAS No. 1075214-55-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4073. | |
| Atorvastatin calcium hydrate | Atorvastatin calcium salt trihydrate is a drug belonging to the statin class of drugs used to lower blood cholesterol levels. Atorvastatin calcium salt trihydrate has unique chemical properties that make it an effective tool in controlling high levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the body, reducing the risk of heart attack and stroke. Atorvastatin calcium salt trihydrate works by inhibiting HMG-CoA reductase, the enzyme responsible for producing cholesterol in the liver. Uses: Scientific research. Group: Natural products. CAS No. 344423-98-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-112490. | |
| Avasimibe | Avasimibe inhibits Lipoprotein(a) accumulation in the culture media of primary monkey hepatocyte in a dose-dependent manner with 11.9% -31.3% inhibition, the change is mainly associated with decreased ApoA. Uses: Cytochrome p-450 cyp3a inducers. Synonyms: CI-1011; CI 1011; CI1011; ((2,4,6-Tris(1-methylethyl)phenyl)acetyl)sulfamic acid 2,6-bis(1-methylethyl)phenyl este; Sulfamic acid, N-[2-[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl esterr. Grades: >98%. CAS No. 166518-60-1. Molecular formula: C29H43NO4S. Mole weight: 501.72. | |
| Azelaoyl PAF | Azelaoyl-PAF is an alkyl phosphatidylcholine and is a component of the lipid pool within oxidized low-density lipoprotein (oxLDL) particles, which contain low molecular weight species. It is a potent PPARγ agonist which competes for the thiazolidinedione binding site. Synonyms: 1-hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine; C16-09:0 (COOH) PC; 1-O-hexadecyl-2-nonadioyl-sn-glycero-3-phosphocholine; 1-O-Hexadecyl-2-O-(9-carboxyoctanoyl)-sn-glyceryl-3-phosphocholine. Grades: >99%. CAS No. 354583-69-0. Molecular formula: C33H66NO9P. Mole weight: 651.85. | |
| Berberine hydrochloride | Berberine hydrochloride is an isoqinoline alkaloid and acts as a COX-2 inhibitor that exhibits chemopreventive activity against colon tumor formation. Study in humans and hamsters shows that berberine reduces total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides. It also inhibits c-Jun and suppresses inflammation and cancers. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Berberine chloride; Natural Yellow 18; Benzodioxide; Berberinium chloride. Grades: ≥ 98%. CAS No. 633-65-8. Molecular formula: C20H18ClNO4. Mole weight: 371.817. | |
| β-Sitosterol | A common sterol in plants. Isolated from wheat germ oil, corn oil. Antilipemic. Used in the treatment of prostatic adenoma. 5-alpha reductase inhibitor. β-sitosterol reduces blood levels of cholesterol, and is sometimes used in treating hypercholesterolemia. β-Sitosterol inhibits cholesterol absorption in the intestine. When the sterol is absorbed in the intestine, it is transported by lipoproteins and incorporated into the cellular membrane. Group: Biochemicals. Alternative Names: (3 β)-Stigmast-5-en-3-ol; Nimbosterol; Stigmast-5-en-3 β-ol; (-)- β-Sitosterol; (24R)-Ethylcholest-5-en-3 β-ol; (24R)-Stigmast-5-en-3 β-ol. Grades: Highly Purified. CAS No. 83-46-5. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C29H50O, Molecular Weight: 414.71. US Biological Life Sciences. | Worldwide |
| BLT-1 | BLT-1, a thiosemicarbazone copper chelator, is a selective scavenger receptor B, type 1 (SR-BI) inhibitor. BLT-1 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. BLT-1 is a potent HCV entry inhibitor. Uses: Designed for use in research and industrial production. Additional or Alternative Names: [(2-hexylcyclopentylidene)amino]thiourea, 2-hexyl-1-cyclopentanone thiosemicarbazone, Block lipid transport-1, BLT1, Probes1_000008, Probes1_000093, Probes2_000390, Probes2_000409, AC1Q2VV0, Ambcb5234221, BLT-1, MolPort-003-180-025, MIT 9952-53, 33M20, EN300-68381, 321673-30-7. Product Category: Inhibitors. Appearance: Solid. CAS No. 321673-30-7. Molecular formula: C12H23N3S. Mole weight: 241.4. Purity: 0.96. IUPACName: [(E)-(2-hexylcyclopentylidene)amino]thiourea. Canonical SMILES: CCCCCCC1CCCC1=NNC(=S)N. Product ID: ACM321673307. Alfa Chemistry ISO 9001:2015 Certified. Categories: BLT Architects. |  |
| Butanoyl PAF | Butanoyl PAF, a compound closely related to Azelaoyl PC (HY-134154), maintains over 10% of the agonist potency of platelet-activating factor ( PAF ). Butanoyl PAF's concentration in oxidized low-density lipoprotein surpasses that of enzymatically generated PAF by more than 100-fold [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 85405-03-4. Pack Sizes: 1 mg. Product ID: HY-W040221. | |
| Campestanol | Campestanol is a phytosterol that can be found in plant food. Campestanol lowers serum cholesterol and low-density lipoprotein. Campestanol can be used for the research of metabolic disorders [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 474-60-2. Pack Sizes: 500 μg; 1 mg. Product ID: HY-113288. | |
| Camu powder | The main beneficial substances contained in Acai include polyphenols, flavonoids, anthocyanins and mostly original anthocyanin classes. Acai's dark purple pericarp contain anthocyanins of red wine is a lot of times, there is a potent antioxidant, containing Omega 6 (linoleic acid) and Omega 9 (oleic acid) of these two essential fatty acids. Studies have shown, Omega 6 helps lower bad cholesterol LDL (low density lipoprotein), and Omega 9 helps lower LDL and maintain good cholesterol HDL (high density lipoprotein) levels. Group: Others. Camu powder acai; Brazilian Acai berry powder. Cat No: EXTC-140. | |
| CAY10485 | Acetyl-CoA acetyltransferase, mitochondrial, also known as acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT (Acetyl-Coenzyme A acetyltransferase) gene. Both ACAT-1 and ACAT-2 are acetyl-CoA C-acetyltransferase enzyme. CAY10485 inhibits human ACAT-1 and ACAT-2 with an IC50 of 95 and 81 μM, respectively. It also inhibits copper-mediated oxidation of low density lipoproteins. Synonyms: 3,4-dihydroxy Hydrocinnamic acid (L-Aspartic acid dibenzyl ester) amide. Grades: ≥98%. CAS No. 615264-62-5. Molecular formula: C27H27NO7. Mole weight: 477.5. | |
| CAY10486 | Acetyl-CoA acetyltransferase, mitochondrial, also known as acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT (Acetyl-Coenzyme A acetyltransferase) gene. Both ACAT-1 and ACAT-2 are acetyl-CoA C-acetyltransferase enzyme. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of 60 μM. It also inhibits copper-mediated oxidation of low density lipoproteins. Synonyms: 4-Hydroxycinnamic acid (L-phenylalanine methyl ester) amide. Grades: ≥98%. CAS No. 615264-52-3. Molecular formula: C19H19NO4. Mole weight: 325.4. | |
| Cerivastatin sodium | Cerivastatin sodium is a synthetic lipid-lowering agent and a highly potent, well-tolerated and orally active HMG-CoA reductase inhibitor, with a K i of 1.3 nM/L. Cerivastatin sodium reduces low-density lipoprotein cholesterol levels. Cerivastatin sodium also inhibits proliferation and invasiveness of MDA-MB-231 cells, mainly by RhoA inhibition, and has anti-cancer effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 143201-11-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109523. | |
| Chemically modified Glycerol-3-phosphate Oxidase from E. coli | Recombinant oxidoreductase that catalyzes the interconversion of glycerol 3-phosphate to dihydroxyacetone phosphate. Take advantage of the enhanced liquid stability of this enzyme. Rely on the proven diagnostic quality of this product. Applications: Use glycerol-3-phosphate oxidase in diagnostic tests for the determination of triglycerides together with glycerol kinase and lipoprotein lipase. Group: Enzymes. Synonyms: glycerol-3-phosphate oxidase; sn-glycerol-3-phosphate: oxygen 2-oxidoreductase; glycerol phosphate oxidase; glycerol-1-phosphate oxidase; glycerol phosphate oxidase; L-alpha-glycerophosphate oxidase; alpha-glycerophosphate oxidase; L-alpha-glycerol-3-phos. Glycerol-3-phosphate oxidase. Mole weight: 75 kD (SDS-PAGE); 74 kD (gel filtration, Sephadex G 150). Activity: >10 U/mg lyophilizate (+37°C, L-α-glycerol phosphate); Specific activity (+25°C): >40 U/mg protein. Stability: At +2 to +8°C within specification range for 12 months. Store dry. Appearance: Green yellow amorphous lyophilizate. Source: E. coli. glycerol-3-phosphate oxidase; EC 1.1.3.21; sn-glycerol-3-phosphate: oxygen 2-oxidoreductase; glycerol phosphate oxidase; glycerol-1-phosphate oxidase; glycerol phosphate oxidase; L-alpha-glycerophosphate oxidase; alpha-glycerophosphate oxidase; L-alpha-glycerol-3-phosphate oxidase. Cat No: DIA-287. | |
| Cholesterol Concentrate, Bovine (BCC) | Bovine Cholesterol Concentrate is a concentrated cholesterol additive consisting mainly of bovine high density lipoproteins. The lipoproteins are substantially free of other serum proteins. Typical cholesterol concentrations are in the range of 6000 to 8000mg/dL. Group: Molecular Biology. Alternative Names: BCC; HDL; High Density Lipoprotein; HDL-C; HDL Concentrate; HDL Fraction; alpha-Lipoprotein. Grades: Molecular Biology Grade. CAS No. 57-88-5. Pack Sizes: 100mg, 1g. US Biological Life Sciences. | Worldwide |
| CI 976 | CI 976 has been found to be a selective inhibitor of Acyl-coenzyme A and could probably lower non-high density lipoprotein (HDL)-cholesterol. Uses: Enzyme inhibitors. Synonyms: CI 976; CI-976; CI976; 2,2-Dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide. Grades: ≥98% by HPLC. CAS No. 114289-47-3. Molecular formula: C23H39NO4. Mole weight: 393.57. | |
| Ciprofibrate-O-β-Glucuronide | Ciprofibrate-O-β-Glucuronide is a derivative of Ciprofibrate. Ciprofibrate is a hypolipemic agent that is structurally related to Clofibrate. Ciprofibrate works primarily by stimulating lipoprotein lipases and hepatic lipases in the breakdown of triglyceride and cholesterol. Synonyms: 1-[2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoate]-β-D-glucopyranuronic Acid; Ciprofibrate glucuronide. Grades: > 95%. CAS No. 102623-15-4. Molecular formula: C19H22Cl2O9. Mole weight: 465.28. | |
| Colesevelam hydrochloride | Colesevelam is a bile acid sequestrant that helps reduce elevated low-density lipoprotein cholesterol (LDL-C) in patients with primary hyperlipidemia, and also improve blood glucose balance in adults with type 2 diabetes mellitus. Synonyms: CholestaGel; GT 31-104; GT 31-104HB; Welchol. CAS No. 182815-44-7. Molecular formula: (C13H27N)n. (C12H27ClN2)n. (C3H7N)n. (C3H5ClO)n. xHCl. | |
| CP-10447 | An inhibitor apolipoprotein B (apoB) and triglyceride secretion in human hepatoma cells (HepG2) by inhibiting MTP activity and stimulating the early ER degradation of apoB. It is useful tool for further study of the mechanisms of apoB secretion and triglyceride-rich lipoprotein assembly. Group: Biochemicals. Alternative Names: 3-(4-Bromo-2-methylphenyl)-2-methyl-4(3H)-quinazolinone; CP 10447; 3-(4-Bromo-o-tolyl)-2-methyl-4(3H)-quinazolinone. Grades: Highly Purified. CAS No. 843-93-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Darapladib | Darapladib (SB-480848) is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.25 nM. Synonyms: SB-480848; SB 480848; SB480848; Darapladib. Grades: >98%. CAS No. 356057-34-6. Molecular formula: C36H38F4N4O2S. Mole weight: 666.77. | |
| Dextran sulfate | Dextran sulfate. CAS No. 9011-18-1. Product ID: 4-00038. Mole weight: Mw 40,000. Properties: Inhibits virus growth and cell aggregation, acts as adjuvant, and precipitates serum lipoproteins, suited for nucleic acid hybridizations; displays anti-HIV activity. Reference: Br. J. Nutr.; 76, 797, 1996; Carbohydr. Polym., 25, 331, 1994; Chemistry and Biology of (1,3)-b-Glucans, B. A. Stone and A. E. Clarke, La Trobe University Press, Australia, 1992. |  |
| Dextrothyroxine sodium | Dextrothyroxine is an antihyperlipidemic. It stimulates the formation of low-density lipoprotein (LDL) and increases the catabolism of LDL thereby leading to increased excretion of cholesterol and bile acids via the biliary route. Synonyms: D-Thyroxine sodium salt; dynothel; Debetrol; 3:5:3':5'-tetraiodo-d-thyroninesodium; biotirmone; choloxin; dethyrona; detyroxin; dextroid; dextrothyroxinesodium; dextroxin. CAS No. 137-53-1. Molecular formula: C15H10I4NNaO4. Mole weight: 798.86. | |
| DiD perchlorate | DiD is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 127274-91-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1028. | |
| DiI | DiI is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: DiIC18(3). CAS No. 41085-99-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D0083. | |
| DiO | DiO is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: DiOC18(3); 3,3'-Dioctadecyloxacarbocyanine perchlorate. CAS No. 34215-57-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0969. | |
| DiR | DiR is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Cy7 DiC18. CAS No. 100068-60-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-D1048. | |
| D-Thyroxine | D-Thyroxine is the dextrorotary isomer of thyroxine with antihyperlipidemic activity. It stimulates the formation of low-density lipoprotein (LDL) and increases the catabolism of LDL thereby leading to increased excretion of cholesterol and bile acids via the biliary route. It is released from thyroglobulin by proteolysis and secreted into the blood. It is one of the thyroid hormones involved in the maintenance of metabolic homeostasis and has been used to treat hyperlipidemia. It is used as an cholesterol-lowering drug but was pulled due to cardiac side-effects. It also increases hepatic lipase which in turn improves utilization of triglycerides, improving apolipoprotein E cholesterol particles. Uses: D-thyroxin is one of the thyroid hormones involved in the maintenance of metabolic homeostasis and has been used to treat hyperlipidemia. it is used as an cholesterol-lowering drug. Synonyms: Dextrothyroxine; Choloxin; Dextrothyroxinum; (R)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoic acid; Biotirmone; Debetrol; D-T4; O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-D-tyrosine. Grades: 95%. CAS No. 51-49-0. Molecular formula: C15H11I4NO4. Mole weight: 776.87. | |
| Eprotirome | Eprotirome is a synthetic thyroid hormone mimetic as a thyroid hormone receptor beta agonists, lowers total and low-density lipoprotein cholesterol up to 40% without affecting high-density lipoprotein cholesterol levels and without deleterious side effects to the cardiovascular system. Uses: Thyroid hormone receptor beta agonists. Synonyms: KB-2115; KB 2115; KB2115; Eprotirome.3-[[3,5-dibromo-4-[4-hydroxy-3-(1-methylethyl)phenoxy]phenyl]amino-3-oxo-propanoic acid. Grades: ≥98%. CAS No. 355129-15-6. Molecular formula: C18H17Br2NO5. Mole weight: 487.14. | |
| Eprotirome | Eprotirome (KB2115) is a liver-selective thyroid hormone receptor (TR) agonist. KB2115 has modestly higher affinity for TRβ than for TR&alpha. Eprotirome reduces low-density lipoprotein (LDL) cholesterol concentrations. Eprotirome can be used for dyslipidemias and obesity research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KB2115. CAS No. 355129-15-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10473. | |
| Evacetrapib | Evacetrapib (LY2484595) is a drug that inhibits cholesterylester transfer protein, which transfers and thereby increases high-density lipoprotein and lowers low-density lipoprotein. Synonyms: LY2484595; LY 2484595; LY-2484595. Grades: 0.98. CAS No. 1186486-62-3. Molecular formula: C31H36F6N6O2. Mole weight: 638.659. | |
| Fenirofibrate O-b-D-glucuronide | Fenirofibrate O-b-D-glucuronide, a remarkable biomedicine, emerges as a key player in addressing dyslipidemia and hyperlipidemia-based afflictions. Acting as a derivative of fibrate, this innovative compound specifically targets the peroxisome proliferator-activated receptor alpha (PPAR-alpha). By skillfully modulating triglyceride levels and amplifying high-density lipoprotein (HDL) cholesterol levels, this medication showcases its unparalleled efficacy in rectifying lipid metabolism disorders. Synonyms: Fenirofibrate O-beta-D-Glucuronide; FENIROFIBRATE O-B-D-GLUCURONIDE; (2S,3S,4S,5R,6R)-6-[[4-(2-carboxypropan-2-yloxy)phenyl]-(4-chlorophenyl)methoxy]-3,4,5-trihydroxyoxane-2-carboxylic acid; beta-D-Glucopyranosiduronic acid, [4-(1-carboxy-1-methylethoxy)phenyl](4-chlorophenyl)methyl; Fenirofibrate O-?-D-Glucuronide. CAS No. 168844-26-6. Molecular formula: C23H25ClO10. Mole weight: 496.90. | |
| Fenofibrate | Antilipemic. It is a lipid regulating drug. Increases high density lipoprotein levels by reducing cholesteryl ester transfer protein expresion. Group: Biochemicals. Alternative Names: 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methyl-propanoic Acid 1-Methylethyl Ester;LF 178; Lipanthyl; Lipantil; Lipidil Supra; Lipirex; Lipoclar; Lipofene; Liposit; Lipsin; MeltDose; NSC 281319; Nolipax; Procetofen; Procetofene. Grades: Highly Purified. CAS No. 49562-28-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Fenofibrate-d6 | Antilipemic. It is a lipid regulating drug. Increases high density lipoprotein levels by reducing cholesteryl ester transfer protein expresion. Group: Biochemicals. Alternative Names: 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methyl-propanoic Acid-d6 1-Methylethyl Ester;LF 178-d6; Lipanthyl-d6; Lipantil-d6; Lipidil Supra-d6; Lipirex-d6; Lipoclar-d6; Lipofene-d6; Liposit-d6; Lipsin-d6; MeltDose-d6; NSC 281319-d6; Nolipax-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Fenofibric Acid | Fenofibric Acid (Fenofibrate EP Impurity B; Fenofibrate USP Related Compound B) is the active metabolite of Fenofibrate (F248640). Increases Apolipoprotein A-I-Mediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptor-dependent manner. Group: Biochemicals. Alternative Names: 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methyl-propanoic Acid; FNF Acid; NSC 281318; Procetofenic Acid; Fenofibrate EP Impurity B; Fenofibrate USP Related Compound B. Grades: Highly Purified. CAS No. 42017-89-0. Pack Sizes: 1g, 5g. Molecular Formula: C??H??ClO?, Molecular Weight: 318.75. US Biological Life Sciences. | Worldwide |
| FR-190809 | FR-190809 is a potent and orally efficacious ACAT inhibitor potentially for the treatment of Lipoprotein Disorders. Synonyms: 1-cycloheptyl-1-[[4-(4-fluorophenoxy)phenyl]methyl]-3-[6-methyl-2,4-bis(methylsulfonyl)pyridin-3-yl]urea; FR-190809; FR 190809; FR190809.N-cycloheptyl-N-(4-(4-fluorophenoxy)-benzyl)-N'-(2,4-bis(methylsulfonyl)-6-methylpyridin-3-yl)urea. Grades: >98%. CAS No. 215589-63-2. Molecular formula: C29H34FN3O6S2. Mole weight: 603.73. | |
| FSL-1 | FSL 1 is a TLR2/6 peptide agonist (also a putative TLR10 ligand) that activates NF-κB. FSL 1 induces the expression of some pro-inflammatory cytokines such as IL-8, IL-1β, CCL20 and TNF-α in vitro. Synonyms: FSL 1; FSL1; L-Phenylalanine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-; S-[2,3-Bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine; FSL-1 lipoprotein, synthetic; Fibroblast-stimulating lipopeptide-1; Pam2-Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-OH. Grades: ≥95%. CAS No. 322455-70-9. Molecular formula: C84H140N14O18S. Mole weight: 1666.16. | |
| FSL-1-FLAG | Lipopeptide FSL-1, synthesized on the basis of the N-terminal structure of M. salivarium lipoprotein, can induce ICAM-1 expression on the surface of human gingival fibroblasts. In addition, it induces the production of monocyte chemoattractant protein 1, interleukin-6 (IL-6), and IL-8. It activates macrophages to produce tumor necrosis factor-alpha. Synonyms: Fibroblast Stimulating Lipopeptide 1 FLAG-tag; H-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-Asp-Tyr-Lys-Asp-Asp-Asp-Asp-Lys-OH; L-Lysine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanyl-L-α-aspartyl-L-tyrosyl-L-lysyl-L-α-aspartyl-L-α-aspartyl-L-α-aspartyl-L-α-aspartyl-. Grades: ≥95%. CAS No. 2243206-97-3. Molecular formula: C125H198N24O37S. Mole weight: 2661.15. | |
| FSL-1 TFA salt | FSL-1 is a TLR2/6 peptide agonist (also a putative TLR10 ligand) that activates NF-κB. FSL-1 induces the expression of some pro-inflammatory cytokines such as IL-8, IL-1β, CCL20 and TNF-α in vitro. Synonyms: FSL 1 TFA salt; FSL1 TFA salt; L-Phenylalanine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-, 2,2,2-trifluoroacetic acid; S-[2,3-Bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine 2,2,2-trifluoroacetic acid; FSL-1 lipoprotein, synthetic TFA salt; Fibroblast-stimulating lipopeptide-1 TFA salt; Pam2-Cys-Gly-Asp-Pro-Lys-His-Pro-Lys-Ser-Phe-OH TFA. Grades: ≥95%. Molecular formula: C86H141F3N14O20S. Mole weight: 1780.18. | |
| Gemcabene | Gemcabene (PD-72953), a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) and lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP), exerting anti-inflammatory activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD-72953. CAS No. 183293-82-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109567. | |
| Gemcabene calcium | Gemcabene calcium (PD-72953 calcium), a first-in-class lipid-lowering agent, lowers low-density lipoprotein cholesterol (LDL-C), decreases triglycerides, and raises high-density lipoprotein cholesterol (HDL-C) and lowers pro-inflammatory acute-phase protein, C-reactive protein (CRP), exerting anti-inflammatory activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD-72953 calcium. CAS No. 209789-08-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-109567A. | |
| Glycerokinase from Cellulomonas sp. | Glycerol kinase is a phosphotransferase enzyme involved in triglycerides and glycerophospholipids synthesis. Glycerol kinase catalyzes tge MgATP-dependent phosphorylation of glycerol to produce sn-glycerol-3-phosphate and is the rate limiting enzyme in the utilization of glycerol. It is also subject to feedback regulation by fructose-1,6-bisphosphate. Phosphoryl moiety of atp to one of the primary hydroxyl group of glycerol, forming sn-glycerol-3-p. the enzyme has the highest specificity for glycerol, and also phosphorylates dihydroxyacetone and glyceraldehyde (table 1,2). mg++ is essentially required for the reaction. Applications: This enzyme is useful for enzymatic deter...se, g3o-301, g3o-311, g3o-321) or pyruvate kinase (pyk-301) and lactate dehydrogenase (lcd-209, lcd-211), lipoprotein lipase (lpl-311, lpl-314) in clinical analysis. Group: Enzymes. Synonyms: EC 2.7.1.30; glycerokinase; GK; ATP:glycerol-3-phosphotransferase; glycerol kinase (phosphorylating); glyceric kinase; 9030-66-4. Enzyme Commission Number: EC 2.7.1.30. CAS No. 9030-66-4. Activity: 20 U/mg-solid or more. Storage: -20°C. Form: Lyophilized powder containing phosphate buffer salts and sodium gluconate. Source: Cellulomonas sp. EC 2.7.1.30; glycerokinase; GK; ATP:glycerol-3-phosphotransferase; glycerol kinase (phosphorylating); glyceric kinase; 9030-66-4. Cat No: NATE-0287. | |
| Glycerokinase from Microorganism | Glycerol kinase is a phosphotransferase enzyme involved in triglycerides and glycerophospholipids synthesis. Glycerol kinase catalyzes tge MgATP-dependent phosphorylation of glycerol to produce sn-glycerol-3-phosphate and is the rate limiting enzyme in the utilization of glycerol. It is also subject to feedback regulation by fructose-1,6-bisphosphate. Applications: This enzyme is useful for enzymatic determination of glycerol and triglyceride when coupled with glycerol-3-phosphate dehydrogenase, glycerol-3-phosphate oxidase or pyruvate kinase and lactate dehydrogenase, lipoprotein lipase in clinical analysis. Group: Enzymes. Synonyms: glycerokinase; GK; ATP: glycerol-3-phosphotransferase; glycerol kinase phosphorylating; glyceric kinase; EC 2.7.1.30. Enzyme Commission Number: EC 2.7.1.30. CAS No. 9030-66-4. Activity: 30 U/mg-solid or more. Appearance: White amorphous powder, lyophilized. Form: Freeze dried powder. Source: Microorganism. glycerokinase; GK; ATP: glycerol-3-phosphotransferase; glycerol kinase phosphorylating; glyceric kinase; EC 2.7.1.30. Cat No: DIA-149. | |
| Glycerol-3-phosphate Oxidase from E. coli, Recombinant | Recombinant oxidoreductase that catalyzes the interconversion of glycerol 3-phosphate to dihydroxyacetone phosphate. Rely on the proven diagnostic quality of this product. Applications: Use glycerol-3-phosphate oxidase in diagnostic tests for the determination of triglycerides together with glycerol kinase and lipoprotein lipase. Group: Enzymes. Synonyms: glycerol-3-phosphate oxidase; sn-glycerol-3-phosphate: oxygen 2-oxidoreductase; glycerol phosphate oxidase; glycerol-1-phosphate oxidase; glycerol phosphate oxidase; L-alpha-glycerophosphate oxidase; alpha-glycerophosphate oxidase; L-alpha-glycerol-3-phosphate oxidase; GPO. CAS No. 9046-28-0. Glycerol-3-phosphate oxidase. Mole weight: 75 kD (SDS-PAGE); 74 kD (gel filtration, Sephadex G 150). Activity: >90 U/mg lyophilizate (+37°C). Stability: At +2 to +8°C within specification range for 12 months. Store dry. Appearance: Greenish yellow lyophilizate. Source: E. coli. glycerol-3-phosphate oxidase; EC 1.1.3.21; sn-glycerol-3-phosphate: oxygen 2-oxidoreductase; glycerol phosphate oxidase; glycerol-1-phosphate oxidase; glycerol phosphate oxidase; L-alpha-glycerophosphate oxidase; alpha-glycerophosphate oxidase; L-alpha-glycerol-3-phosphate oxidase. Cat No: DIA-286. | |
| Glycerol-3-phosphate oxidase from Microorganism | In enzymology, a glycerol-3-phosphate oxidase (EC 1.1.3.21) is an enzyme that catalyzes the chemical reaction: sn-glycerol 3-phosphate + O2 ? glycerone phosphate + H2O2. Thus, the two substrates of this enzyme are sn-glycerol 3-phosphate and O2, whereas its two products are glycerone phosphate and H2O2. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. This enzyme participates in glycerophospholipid metabolism. It employs one cofactor, FAD. Applications: This enzyme is useful for enzymatic determination of triglyceride when coupled with lipoprotein lipase and glycerokinase in clinical analysis. Group: Enzymes. Synonyms: L-α-glycerophosphate oxidase; sn-glycerol-3-phosphate: oxygen 2-oxidoreductase; glycerol phosph. Enzyme Commission Number: EC 1.1.3.21. CAS No. 9046-28-0. Activity: 15 U/mg-solid or more (containing approx. 60% of stabilizers). Appearance: Yellowish amorphous powder, lyophilized. Form: Freeze dried powder. Source: Microorganism. L-α-glycerophosphate oxidase; sn-glycerol-3-phosphate: oxygen 2-oxidoreductase; glycerol phosphate oxidase; glycerol-1-phosphate oxidase; glycerol phosphate oxidase; L-alpha-glycerophosphate oxidase; alpha-glycerophosphate oxidase; L-alpha-glycerol-3-phosphate oxidase; EC 1.1.3.21. Cat No: DIA-200. | |
| Grape seed extract | Grape seed extract is a natural product, with anti-inflammatory and anti-proliferative effects. Grape seed extract shows inhibitory activity on the fat-metabolizing enzymes pancreatic lipase and lipoprotein lipase. Grape seed extract induces apoptotic in human colorectal cancer cells [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 84929-27-1. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-N7072. | |
| GSK 264220A | GSK 264220A is an endothelial lipase and lipoprotein lipase inhibitor (IC50 = 0.13 and 0.10 μM, respectively). Inhibition of endothelial lipase may lead to an increase in HDL levels and GSK 264220A is expected to be a therapy for cardiovascular disease. Uses: Potential treatment of cardiovascular disease. Synonyms: GSK-264220A; GSK 264220A; GSK264220A. N-[2-Methyl-5-(1-piperidinylsulfonyl)-3-furanyl]-N'-phenylurea; 3-[2-methyl-5-(piperidine-1-sulfonyl)furan-3-yl]-1-phenylurea; 1-(2-methyl-5-piperidin-1-ylsulfonylfuran-3-yl)-3-phenylurea. Grades: ≥98% by HPLC. CAS No. 685506-42-7. Molecular formula: C17H21N3O4S. Mole weight: 363.43. | |
| Heparinase I from Bacteroides eggerthii, Recombinant | Heparin-degrading lyase that recognizes heparin sulfate proteoglycan as its primary substrate. Heparinase I and III plays vital role in various biological processes: modulate cell-growth factor interactions, cell-lipoprotein interactions, neovascularization. It cleaves highly sulphated polysaccharide chains in presence of 2-O-sulfated α-L-idopyranosyluronic acid and β-D-glucopyranosyluronic acid residues of polysaccharides. Bacteroides heparinase i cloned from bacteroides eggerthii, also called heparin lyase i, is active on heparin and the highly sulfated domains of heparan sulfate. the reaction yields oligosaccharide products containing unsaturated uroni...heparinase i has a much higher rate of cleavage for 2-o sulfated iduronic acid residues. limited digest of porcine mucosal heparin with flavobacterium heparinum heparinase i results in sulfated heparin oligosaccharides structures previously reported. limited digest of porcine mucosal heparin with the bacteroides heparinase i results in heparin oligosaccharides with a lower extent of sulfation as reported. Group: Enzymes. Synonyms: Heparinase; Heparin lyase; Heparin eliminase; Heparin-sulfate lyase; Heparin-sulfate eliminase; Heparitin-sulfate lyase; Heparinase I; Heparinase III; Heparin lyase II; Heparinase II. CAS No. 9025-39-2. Purity: > 95% determined by SDS-PAGE | |
| Heparinase I from Flavobacterium heparinum, Recombinant | Heparin-degrading lyase that recognizes heparin sulfate proteoglycan as its primary substrate. Heparinase I and III plays vital role in various biological processes: modulate cell-growth factor interactions, cell-lipoprotein interactions, neovascularization. It cleaves highly sulphated polysaccharide chains in presence of 2-O-sulfated α-L-idopyranosyluronic acid and β-D-glucopyranosyluronic acid residues of polysaccharides. Group: Enzymes. Synonyms: Heparinase; Heparin lyase; Heparin eliminase; Heparin-sulfate lyase; Heparin-sulfate eliminase; Heparitin-sulfate lyase; Heparinase I. Enzyme Commission Number: EC 4.2.2.7. CAS No. 9025-39-2. Heparinase. Activity: > 400 IU/mg. Stability: Expiration of heparinase I is 12 months from manufacturing date, frozen at -96 to -20 °C in PBS. Form: Solution. Source: E.coli. Species: Flavobacterium heparinum. Heparinase; Heparin lyase; Heparin eliminase; Heparin-sulfate lyase; Heparin-sulfate eliminase; Heparitin-sulfate lyase; Heparinase I. Cat No: NATE-1946. | |
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