Luciferase Suppliers USA
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Product | Description | |
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Luciferase Quick inquiry Where to buy Suppliers range | Luciferase is an analytical enzyme used as a component of lysis solution to measure luminescence signals. It has been used to investigate the sensitivity of dark mutants of various luminescent bacterial strains to reactive oxygen species. Synonyms: EC 1.14.14.3; Bacterial Luciferase; Luciferase from Photobacterium fischeri. Grades: >95%. CAS No. 9014-00-0. | |
Luciferase Quick inquiry Where to buy Suppliers range | Luciferase from Vibrio fischeri has also been used in a study to investigate the sensitivity of dark mutants of various strains of luminescent bacteria to reactive oxygen species. Uses: Peptide Inhibitors. CAS No. 9014-00-0. Product ID: R1492. | |
Luciferase, firefly Quick inquiry Where to buy Suppliers range | Luciferase, firefly is the light-emitting enzyme responsible for the bioluminescence of fireflies and click beetles. Uses: Peptide Inhibitors. CAS No. 61970-00-1. Product ID: R1493. | |
Luciferase, firefly Quick inquiry Where to buy Suppliers range | Luciferase, firefly is a bioluminescent enzyme responsible for bioluminescence in fireflies and click beetles. Synonyms: Luciferase from Photinus pyralis (firefly). Grades: >98%. CAS No. 61970-00-1. | |
Luciferase from Vibrio fischeri Quick inquiry Where to buy Suppliers range | Luciferase from Vibrio fischeri. Group: Biochemicals. Grades: Highly Purified. CAS No. 9014-00-0. Pack Sizes: 100mg, 250mg, 500mg. US Biological Life Sciences. | Worldwide |
AMPK Signaling Activator XIII, ZLN005 (2-(4-tert-Butylphenyl)-1H-benzo[d]imidazole, 2-(4-(2-Methyl-2-propanyl)phenyl)-1H-benzimidazole, Luciferase Inhibitor IV) Quick inquiry Where to buy Suppliers range | A cell-permeable benzimidazole that, in addition to its inhibitory potency against luciferase activity (IC50 <10nM), also activates AMPK signaling by increasing cellular ADP/ATP ratio via mitochondria respiration upcoupling, effectively activating AMPK & PGC-1alpha in muscle, but not liver, cell types both in cultures (5-20uM in rat L6 myotubes) in vitro and in db/db mice (15mg/kg/day via p.o.) in vivo. Reported to improve glucose and insulin tolerance of db/db mice without any apparent effects on body weight or food intake. Group: Biochemicals. Grades: Highly Purified. CAS No. 4529-96-8. Pack Sizes: 25mg. Molecular Formula: C??H??N?. US Biological Life Sciences. | Worldwide |
17α-Ethinyl-17 β-acetoxy-3,5-estradiene Quick inquiry Where to buy Suppliers range | 17α-Ethinyl-17 β-acetoxy-3,5-estradiene is derived from Ethynodiol (E932120), which is a steroidal progestin that inhibits luciferase expression. Also, it is an impurity of the drug Norethindrone Acetate (N675990). Group: Biochemicals. Grades: Highly Purified. CAS No. 64850-62-0. Pack Sizes: 1mg, 5mg. Molecular Formula: C22H28O2, Molecular Weight: 324.459999999999. US Biological Life Sciences. | Worldwide |
1,9-Nonanediol Quick inquiry Where to buy Suppliers range | 1,9-Nonanediol is found to be a general anesthetic that can inhibit the firefly luciferase enzyme from Photinus pyralis by competing with its normal substrate firefly luciferin. 1,9-Nonanediol can also inhibit the bacterial luciferase enzyme from Vibrio Harveyi by competing with the substrate n-decanal. Group: Biochemicals. Grades: Highly Purified. CAS No. 3937-56-2. Pack Sizes: 10g, 50g. Molecular Formula: C9H20O2, Molecular Weight: 160.25. US Biological Life Sciences. | Worldwide |
2-Chlorobenzaldehyde Oxime Quick inquiry Where to buy Suppliers range | 2-Chlorobenzaldehyde Oxime is a chemical reagent used in the synthesis of antimicrobial hydroxamates which are potential inhibitors of deoxy-D-xylulose 5-phosphate synthase inhibiting growth of influenzae. Also used in the preparation ofsubstituted oxazole based firefly luciferase inhibitors. Group: Biochemicals. Alternative Names: 2-Chlorobenzaldehyde oxime; 2-Chlorobenzaldoxime; NSC 61415; o-Chlorobenzaldehyde oxime; o-Chlorobenzaldoxime. Grades: Highly Purified. CAS No. 3717-28-0. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
2-?Propyl-1,?3-?Dioxolane-?2-?acetic Acid Quick inquiry Where to buy Suppliers range | 2-?Propyl-1,?3-?Dioxolane-?2-?acetic Acid is an intermediate in synthesizing N-(Ketocaproyl)-L-homoserine Lactone (K180750), an autoinducer of P. fischeri luciferase. A specific genetic regulator that is unrelated to at least one of the enzyme systems that it induces, and it acts after excretion and accumulation in the extracellular medium. Group: Biochemicals. Grades: Highly Purified. CAS No. 5735-99-9. Pack Sizes: 500mg, 1g. Molecular Formula: C8H14O4. US Biological Life Sciences. | Worldwide |
2-Propyl-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-1,3-dioxolane-2-acetamide Quick inquiry Where to buy Suppliers range | 2-Propyl-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-1,3-dioxolane-2-acetamide is an intermediate in synthesizing N-(Ketocaproyl)-L-homoserine Lactone (K180750), an autoinducer of P. fischeri luciferase. A specific genetic regulator that is unrelated to at least one of the enzyme systems that it induces, and it acts after excretion and accumulation in the extracellular medium. Group: Biochemicals. Grades: Highly Purified. CAS No. 1083287-09-5. Pack Sizes: 250mg, 500mg. Molecular Formula: C12H19NO5. US Biological Life Sciences. | Worldwide |
5-(4-Methoxyphenyl)-2-pyridinamine Quick inquiry Where to buy Suppliers range | Used in the preparation of luciferase inhibitors, substituted triazoles as antifungal agents and PhIP (A617000) metabolites and derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 503536-75-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
6-Iodonordihydrocapsaicin Quick inquiry Where to buy Suppliers range | 6-Iodonordihydrocapsaicin is a potent and competitive vanilloid TRPV1 (VR1) receptor antagonist with IC50 value of 10 nM. It inhibits capsaicin-induced [Ca2+]i increase in rat DRG neurons. It also inhibits guinea pig bladder and trachea contractions in vitro. It may induce luciferase gene expression. Synonyms: N-[(4-Hydroxy-2-iodo-5-methoxyphenyl)methyl]nonanamide; 6-I-CPS. Grades: ≥99% by HPLC. CAS No. 859171-97-4. Molecular formula: C17H26INO3. Mole weight: 419.30. | |
CCG-100602 Quick inquiry Where to buy Suppliers range | CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells with an IC50 value of 9.8 μM. CCG-100602 specifically blocks the nuclear localization of MRTF-A, thereby inhibiting the fibrogenic transcription factor SRF. Synonyms: CCG-100602; 1207113-88-9; 1-[3,5-bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)piperidine-3-carboxamide; CHEMBL603141; compound 4g [PMID: 19963382]; 1-(3,5-bis(trifluoromethyl)benzoyl)-N-(4-chlorophenyl)piperidine-3-carboxamide; CCG100602; CCG 100602; GTPL6764; SCHEMBL1534209; BDBM50436237; AKOS040744973; MS-28902; HY-120855; CS-0079376; Q27075763; [3,5-bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)piperidine-3-carboxamide; 1-[3,5-bis (trifluoromethyl)benzoyl]-N-(4-chlorophenyl)-3-piperidinecarboxamide. Grades: 98%. CAS No. 1207113-88-9. Molecular formula: C21H17ClF6N2O2. Mole weight: 478.8. | |
Cetrorelix Acetate Quick inquiry Where to buy Suppliers range | Cetrorelix Acetate is the acetate salt of cetrorelix, which is a potent and synthetic peptide antagonist of gonadotropin-releasing hormone (GnRH) receptor antagonist with IC50 value of 1.21 nM. It binds to radioligand murine LTK- cells with Kd value of 0.2 nM. It inhibits the activation of hGnRHR and a downstream luciferase reporter gene in murine LTK- cells by the GnRHR agonist [D-Trp6]GnRH. It suppresses production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary gland. It prevents ovulation during in vitro fertilization. It causes prepubertal reduction in bone density, bone strength and bone modeling. It was used as a therapeutic agent for the treatment of blood cancers such as multiple myeloma (MM). It is also used to treat hormone-sensitive cancers of the breast and prostate. It also has antidepressant and anxiolytic activity in vivo. Uses: Fertility agents, female. Synonyms: D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, acetate (1:x); D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, acetate (salt); Cetrotid; Cetrotide; D 20761; NS 75A; Ovurelix; SB 075 acetate; Ac-D-2Nal-D-Phe(4-Cl)-D-3Pal-Ser-Tyr-D-Cit-Leu-Arg-Pro-D-Ala-NH2.CH3CO2H. Grades: >98%. CAS No. 145672-81-7. Molecular formula: C70H92ClN17O14.xC2H4O2. Mole weight: 1431.06 (free base). | |
CID 1375606 Quick inquiry Where to buy Suppliers range | CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27. Promotes recruitment of β-arrestin 2 to chimeric GPR27V2 and wild-type GPR27 in a firefly luciferase complementation assay (pEC50 values are 6.34 and 5.1, respectively). GPR27 is characterized by a high level of conservation among vertebrates and a predominant expression in the central nervous system. In addition, it has recently been linked to insulin secretion. Synonyms: 2,4-Dichloro-N-(phenylcarbamoyl)phenylbenzamide; 2,4-Dichloro-N-(4-(phenylcarbamoyl)phenyl)benzamide. Grades: ≥98% by HPLC. CAS No. 313493-80-0. Molecular formula: C20H14Cl2N2O2. Mole weight: 385.24. | |
Coelenterazine Quick inquiry Where to buy Suppliers range | Coelenterazine is a luciferin, a light-emitting biomolecule that serves as a substrate for luciferases or as a constituent of photoproteins, including aequorin.1 The oxidation of coelenterazine to coelenteramide is accompanied by emission of blue light (emission maximum, 460-470 nm). Luciferase-mediated oxidation of coelenterazine or a derivative is used as an energy donor, typically to a form of green or yellow fluorescent protein, in bioluminescent resonance energy transfer studies.2,3 Alternatively, the calcium-mediated release of coelenterazine from aequorin, followed by non-enzymatic oxidation of this compound, results in bioluminescence. As light emission depends on both calcium and cellular redox status, this reaction is used to non-fluorescently detect changes in calcium level and redox status.4,5. Group: Biochemicals. Alternative Names: 3,2-Dihydro-2-(p-hydroxybenzyl)-6-(p-hydroxyphenyl)-8-benzylimidazolo[1,2-a]pyrazin-3-one; CLZN; Preluciferin; Luciferin; 6-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-8-(phenylmethyl)-imidazo[1,2-a]pyrazin-3(7H)-one. Grades: Highly Purified. CAS No. 55779-48-1. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C??H??N?O?, Molecular Weight: 423.46. US Biological Life Sciences. | Worldwide |
CP21R7 Quick inquiry Where to buy Suppliers range | CP21R7 is a potent and selective GSK3β inhibitor. It acts as an activator of stem cells prior to the induction of differentiation of stem cells to endothelial and smooth muscle cells. Uses: Cp21r7 is a selective gsk-3β inhibitor which could probably influence luciferase activity at some extent. Synonyms: 3-(3-aminophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione. Grades: >98%. CAS No. 125314-13-8. Molecular formula: C19H15N3O2. Mole weight: 317.34. | |
D-Luciferin-6-O b-D-galactopyranoside Quick inquiry Where to buy Suppliers range | D-Luciferin-6-O b-D-galactopyranoside is a versatile tool in compound utilized for studying the activity of luciferase enzymes in various research applications. This compound is commonly employed in in vitro and in vivo bioluminescence imaging assays is aiding in the investigation of gene expressions, protein interactions and visualization of cellular processes. Synonyms: 6-O-(b-D-Galactopyranosyl)luciferin. CAS No. 131474-38-9. Molecular formula: C17H18N2O8S2. Mole weight: 442.47. | |
D-Luciferin-6-O b-D-glucopyranoside Quick inquiry Where to buy Suppliers range | D-Luciferin-6-O b-D-glucopyranoside is a crucial compound acting as a useful substrate for luciferase enzymes to emit bioluminescence signals. This product is widely employed in the field of molecular imaging and bioluminescence assays due to its ability to track luciferase-expressing cells or organisms in vivo. It is a valuable tool for studying various diseases, including cancer, infectious diseases and neurological disorders. Molecular formula: C17H18N2O8S2. Mole weight: 442.47. | |
D-Luciferin potassium salt Quick inquiry Where to buy Suppliers range | D-Luciferin potassium salt is a chemiluminescent substrate of firefly luciferase. Synonyms: (4S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic Acid Monopotassium Salt; 4-Thiazolecarboxylic acid, 4,5-dihydro-2-(6-hydroxy-2-benzothiazolyl)-, potassium salt (1:1), (4S)-; Firefly luciferin potassium salt. Grades: 95%. CAS No. 115144-35-9. Molecular formula: C11H7KN2O3S2. Mole weight: 318.41. | |
EDA-ATP - DYQ-660 Quick inquiry Where to buy Suppliers range | EDA-ATP, a nucleotide analogue frequently utilized in the biomedical industry, functions as a valuable substrate for luciferase-based assays designed to gauge ATP concentration and activity. Widely applicable in the study of various ailments including muscular dystrophy as well as drug efficacy in treating cancer and neurological disorders, its potential applications seem endless. When utilized in concert with DYQ-660, a fluorescent dye able to be coupled with EDA-ATP for purposes of imaging, this product provides a powerhouse duo for accurate measurement and imaging. Synonyms: 2'/3'-O-(2-Aminoethyl-carbamoyl)-Adenosine-5'-triphosphate, labeled with DYQ 660, Triethylammonium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C52H64N9O19P3S (free acid). Mole weight: 1244.11 (free acid). | |
Ethaselen Quick inquiry Where to buy Suppliers range | Ethaselen, also known as BBSKE, is a novel organoselenium thioredoxin reductase inhibitor, is currently being investigated in a phase I clinical trial in China. Ethaselen enhanced the efficacy of radiation therapy both in vivo and in vitro without observable toxicity. BBSKE was found to suppress irradiation-induced activation dramatically when using A549 cells stably transfected with luciferase reporter. Ethaselen is a potentially promising agent for the treatment of patients with NSCLC clinically. Synonyms: 1,2-[bis(1,2-benzisoselenazolone-3(2H)-ketone)]ethane; BBSKE. CAS No. 217798-39-5. Molecular formula: C16H12N2O2Se2. Mole weight: 422.199. | |
Ethynodiol Quick inquiry Where to buy Suppliers range | Ethynodiol is a steroidal progestin that inhibits luciferase expression. Uses: Contraceptives, oral, synthetic. Synonyms: (3β,17α)-19-Norpregn-4-en-20-yne-3,17-diol; 19-Nor-17α-pregn-4-en-20-yne-3β,17-diol. Grades: > 95%. CAS No. 1231-93-2. Molecular formula: C20H28O2. Mole weight: 300.44. | |
Ethynodiol-17-Acetate Quick inquiry Where to buy Suppliers range | A derivative of Ethynodiol. Ethynodiol is a steroidal progestin that inhibits luciferase expression. Synonyms: (3β,17α)-19-Norpregn-4-en-20-yne-3,17-diol 17-Acetate; 19-Nor-17α-pregn-4-en-20-yne-3β,17-diol 17-Acetate. Grades: > 95%. CAS No. 2061-46-3. Molecular formula: C22H30O3. Mole weight: 342.48. | |
Ethynodiol Impurity Quick inquiry Where to buy Suppliers range | An impurity of Ethynodiol. Ethynodiol is a steroidal progestin that inhibits luciferase expression. Synonyms: 17-alfa-Ethinyl-17-beta-Acettoxy-3,5-Estradien Impurity. Grades: > 95%. CAS No. 64850-62-0. Molecular formula: C22H28O2. Mole weight: 324.47. | |
Hh Signaling Antagonist XII, MRT-83 (N- (2-Methyl-5- (3- (3, 4, 5-trimethoxybenzoyl) guanidino) phenyl) - (1, 1-biphenyl) -4-carboxamide) Quick inquiry Where to buy Suppliers range | A cell-permeable acylguanidine compound that is shown to block Hh signaling and act as a potent, reversible and high-affinity Smo (Smoothened) antagonist. Displays 20-60 -fold greater potency than Cyclopamine and competitively inhibits bodipy-cyclopamine binding to Smo (IC50 = 4.6 and 14nM in HEK293-hSMO and HEK293-mSMO cells, respectively). Represses ShhN (N-myristoylated Shh) signaling (IC50=15nM for Gli-dependent luciferase activity in Shh-light2 cells) and SAG- induced C3H10T1/2 cell differentiation (IC50=10nM in an alkaline phosphatase activity assay). Inhibits ShhN (3nM) and SAG (10nM)-mediated proliferation of rat cerebellar granule cell precursors (IC50 ~3 and 6nM, respectively). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
iCRT5 Quick inquiry Where to buy Suppliers range | iCRT5 is a Potent and cell-permeable β-catenin-responsive transcription (CRT) inhibitor (IC50 value of 18 nM for Wnt responsive STF16 luciferase). iCRT5 disrupts the interaction between β-catenin and TCF4, possibly by direct binding to β-catenin. Synonyms: iCRT5; iCRT-5; iCRT 5; 4-[5-(3,4-Dimethoxy-benzylidene)-4-oxo-2-thioxo-thiazolidin-3-yl]-butyric acid; 4-[(5Z)-5-[(3,4-dimethoxyphenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoic acid; EN300-00774; AC1Q49FJ. Grades: 99%. CAS No. 18623-44-4. Molecular formula: C16H17NO5S2. Mole weight: 367.44. | |
LY 364947 Quick inquiry Where to buy Suppliers range | Selective inhibitor of TGF- β type-I receptor (TGF- β RI, TGFR-I, T βR-I, ALK-5) (IC50 values are 59, 400 and 1400nM for TGR- β RI, TGF- β RII and MLK-7K respectively). Inhibits TGF- β-dependent luciferase production in mink lung cells (p3TP lux) and growth in mouse fibroblasts (NIH 3T3) (IC50 values are 47 and 89nM respectively). Suppresses invasion of MDA-MB-231 breast cancer cells in a matrigel invasion assay. Group: Biochemicals. Alternative Names: 4-[3-(2-pyridinyl)-1H-pyrazol-4-yl]quinoline; E 616451; HTS 466284. Grades: Highly Purified. CAS No. 396129-53-6. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C??H??N?, Molecular Weight: 272.3. US Biological Life Sciences. | Worldwide |
LY-364947 Quick inquiry Where to buy Suppliers range | LY364947 is a selective inhibitor of TGF-β type-I receptor with potential anticancer activity. LY364947 inhibits TGF-β-dependent luciferase production in mink lung cells (p3TP lux) and growth in mouse fibroblasts (NIH 3T3). Uses: Reprogramming. Synonyms: LY364947; LY-364947; LY 364947; HTS 466284; HTS466284; HTS-466284. Grades: 98%. CAS No. 396129-53-6. Molecular formula: C17H12N4. Mole weight: 272.31. | |
M 25 Quick inquiry Where to buy Suppliers range | M 25 is a potent Smoothened (Smo) receptor antagonist with IC50 value of 5 nM. It inhibits the Hedgehog signaling pathway. It also inhibits Shh induced Gli luciferase reporter activity in Shh-light 2 cells. It antagonizes GSA-10 and SAG-mediated differentiation of the C3H10T1/2 cell line. Synonyms: M 25; M25; M-25; N-[[1-(2-Methoxyphenyl)-1H-indazol-5-yl]methyl]-2-propylpentanamide. Grades: ≥98% by HPLC. Molecular formula: C23H29N3O2. Mole weight: 379.50. | |
MN-64 Quick inquiry Where to buy Suppliers range | MN-64 is a very potent and selective inhibitor of Tankyrase 1 and 2 with IC50 values of 6 and 72 nM, respectively. It blocks Wnt signaling in HEK293 cells containing a Wnt pathway reporter system. It affects cell proliferation with potential treatment for cancers. It is a flavonoid compound with anti-cancer/ anti-bacterial properties. It was effective Wnt/β- catenin inhibitors at 1 μM, and inhibited STF luciferase activity at 200 nM in the HEK293 cells in vitro. Uses: Mn-64 has anti-cancer/ anti-bacterial properties and is used for the treatment for cancers. Synonyms: MN-64; MN 64; MN64. 2-(4-Isopropylpheny)-4H-chroMen-4-one;2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one;MN64;2-(4-propan-2-ylphenyl)chromen-4-one. Grades: >98%. CAS No. 92831-11-3. Molecular formula: C18H16O2. Mole weight: 264.32. | |
MPC-3100 Quick inquiry Where to buy Suppliers range | MPC-3100 targets the N-terminal ATP-binding site of Hsp90 and blocks the activity of ATPase. In the Her2-luciferase degradation assay, MPC-3100 reduces this client protein of Hsp90 with IC50 value of 60nM. In HCT-116 cell lines, MPC-3100 inhibits cell proliferation with IC50 value of 540 nM. Besides that, MPC-3100 shows a broad spectrum anti-proliferative activity against various cancer cell lines, such as NCI-N87 and DU-145. MPC-3100 also inhibits tumor growth in the NCI-N87 gastric cancer xenograft mode. Moreover, PK studies show that MPC-3100 displays a superior oral PK profile, good overall exposure and a reasonable hepatic clearance rate. Phase I clinical studies demonstrate MPC-3100 is safe and tolerated when administered at doses below 600 mg per day. Synonyms: MPC-3100; MPC 3100; MPC3100. Grades: >98%. CAS No. 958025-66-6. Molecular formula: C22H25BrN6O4S. Mole weight: 549.40. | |
MPP dihydrochloride Quick inquiry Where to buy Suppliers range | MPP dihydrochloride is a selective, high affinity silent antagonist at ERα receptors, with > 200-fold selectivity for ERα over Erβ (Ki= 2.7 and 1800 nM at ERα and ERβ receptors respectively). It cannot block EE2 induced luciferase activity with any isoform of zebrafish estrogen receptor. Synonyms: 1,3-Bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidinylethoxy)phenol]-1H-pyrazole dihydrochloride. Grades: ≥98% by HPLC. CAS No. 911295-24-4. Molecular formula: C29H31N3O3.2HCl. Mole weight: 542.5. | |
N-(KETOCAPROYL)-L-HOMOSERINE LACTONE Quick inquiry Where to buy Suppliers range | N-(3-Oxohexanoyl)-L-homoserine lactone, 143537-62-6, N-(beta-Ketocaproyl)-L-homoserine lactone, N-(Ketocaproyl)-L-homoserine Lactone, (S)-3-oxo-N-(2-oxotetrahydrofuran-3-yl)hexanamide, CHEBI:63789, 3-oxo-N-[(3S)-2-oxooxolan-3-yl]hexanamide, 3-Oxo-C6-HSL, VAI-1, 3-oxo-N-[(3S)-2-oxotetrahydrofuran-3-yl]hexanamide, CHEMBL458201, (S)-3-(3-oxohexanamido)butyrolactone, (S)-3-(3-ketohexanamido)butyrolactone, N-(3-ketocaproyl)-L-homoserine lactone, N-(3-ketohexanoyl)-L-homoserine lactone, (S)-3-(3-oxohexanamido)-2-oxotetrahydrofuran, (S)-3-(3-ketohexanamido)-2-oxotetrahydrofuran, AI-1 (Vibrio fischeri), Autoinducer I, SCHEMBL136646, 3-Oxohexanoyl-homoserine lactone, autoinducer 1 (Vibrio fischeri), autoinducer 1 (Aliivibrio fischeri), L-3-Oxo-hexanoyl-homoserine lactone, BDBM50526999, MFCD00171363, AKOS040745056, CS-W009522, HY-W008806, N-(-Ketocaproyl)-L-homoserine lactone, N-(bet.-Ketocaproyl)-L-homoserine lactone, N-( beta -ketocaproyl)-L-Homoserine lactone, N-(.beta.-Ketocaproyl)-L-homoserine lactone, C21198, N-3-oxohexanoyl)-3-aminodihydro-2(3H)-furanone, N-(beta-Ketocaproyl)-L-homoserine lactone, >=98%, Q27132806, Hexanamide, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-, 76924-95-3, N-(3-Oxohexanoyl)homoserine lactone, Autoinducer 1, 3-oxo-n-(2-oxotetrahydrofuran-3-yl)hexanamide, AI-1 Lactone, N-(KETOCAPROYL)-D,L-HOMOSERINE LACTONE, Luciferase autoinducer, N-(3-Oxohexanoyl)-3-aminodihydro-2(3H)-furanone, Ohhl-N, 3-oxo-N-(2-oxooxolan-3-yl)hexanamide, 3-Oxo-N-(tetrahydro-2-oxo-3-furanyl)hexanamide, N-(Ketocaproyl)-DL-homoserine lactone, N-(beta-Ketocaproyl)-DL-homoserine lactone, CHEBI:29640, N-(Ketocaproyl)-L-homoserine Lactone, N-3-Oxohexanoyl-L-homoserine lactone, N-(beta-Ketocaproyl)homoserine lactone, N-(3-oxo-hexanoyl)-homoserine lactone, N-(3-Oxohexanoyl)-DL-homoserine lactone, AI-1 (Vibrio fischeri), MFCD03788849, N-(3-Oxohexanoyl)-homoserine Lactone, starbld0013715, 3-oxo-C6-AHL, 3-oxo-N-(2-oxotetrahydro-3-furanyl)hexanamide, 3OC6-HSL, SCHEMBL79602, 3-oxo-C6-homoserine lactone, CHEMBL16203, DTXSID20998213, LMFA08030003, AKOS005107755, MS-2575, N-(-Ketocaproyl)-DL-homoserine lactone, N-(beta-ketocapryloyl)-homoserine lactone, HY-129405, N-(bet.-Ketocaproyl)-DL-homoserine lactone, CS-0105302, FT-0670618, 3-Oxo-N-(2-oxooxolan-3-yl)hexanimidic acid, N-(2-Oxotet | |
N-(Ketocaproyl)-L-homoserine Lactone (N-(3-Oxohexanoyl)-homoserine Lactone) Quick inquiry Where to buy Suppliers range | An autoinducer of P. fischeri luciferase. A specfic genetic regulator that is unrelated to at least one of the enzyme systems that it induces, and it acts after excretion and accumulation in the extracellular medium. Group: Biochemicals. Alternative Names: N-(3-Oxohexanoyl)-homoserine Lactone. Grades: Highly Purified. CAS No. 143537-62-6. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
Ochromycinone ((S)-Ochromycinone, (+)-Ochromycinone, Deoxytetrangomycin, STA-21. (3S)-3,4-Dihydro-8-hydroxy-3-methyl-Benz[a]anthracene-1,7,12(2H)-trione) Quick inquiry Where to buy Suppliers range | An angucycline antibiotic. A novel STAT3 selective inhibitor. It inhibits STAT3 dimerazation and DNA binding as well as STAT3-dependent luciferase reporter activity. Group: Biochemicals. Alternative Names: (S)-Ochromycinone, (+)-Ochromycinone, Deoxytetrangomycin, STA-21(3S)-3,4-Dihydro-8-hydroxy-3-methyl-Benz[a]anthracene-1,7,12(2H)-trione. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
SID 7969543 Quick inquiry Where to buy Suppliers range | SID 7969543 is a selective steroidogenic factor-1 (SF-1, NR5A1) inhibitor (IC50 = 0.76, >33 and >33 μM at SF-1, RORα and VP16, respectively). It also inhibits SF-1-dependent luciferase expression in HEK 293T cells in vitro (IC50 = 30 nM). Synonyms: SID 7969543; SID7969543; SID-7969543; Ethyl 2-[[2-[2-[(2,3-Dihydro-1,4-benzodioxin-6-yl)amino]-2-oxoethyl]-1,2-dihydro-1-oxo-5-isoquinolinyl]oxy]propanoate. Grades: ≥98% by HPLC. CAS No. 868224-64-0. Molecular formula: C24H24N2O7. Mole weight: 452.46. | |
SM 16 Quick inquiry Where to buy Suppliers range | SM 16 is a potent and selective TGF-β receptor type 1 (TGF-βRI) inhibitor with IC50 value of 64 nM in luciferase assay. SM 16 blocked TGF-beta and activin-induced Smad2/3 phosphorylation and TGF-beta-induced plasminogen activator inhibitor (PAI)-luciferase activity in cells. Synonyms: SM-16; SM16; 4-[4-(1,3-Benzodioxol-5-yl)-5-(6-methyl-2-pyridinyl)-1H-imidazol-2-yl]bicyclo[2.2.2]octane-1-carboxamide. Grades: ≥98% by HPLC. CAS No. 614749-78-9. Molecular formula: C25H26N4O3. Mole weight: 430.5. | |
STAT3 Inhibitor XVI (IL-6 Inhibitor) Quick inquiry Where to buy Suppliers range | A cell-permeable, arylsulphonamidyl thiophene amide that is shown to reduce IL-6-induced STAT3 transcriptional activity (EC50=15uM) in a luciferase reporter assay, in HeLa cells. It selectively inhibits STAT3, but not STAT1, phosphorylation following IL-6 stimulation in both HeLa and MDA-MB-231 breast cancer cells at concentrations of 10-30uM and 30-100uM, respectively. Following IL-6 stimulation, it suppresses the cell viability of STAT3-dependent cancer cells by 40% compared with that of STAT3-null cancer cells at the low micromolar level. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Stresgenin B Quick inquiry Where to buy Suppliers range | Stresgenin B is a heat-induced heat shock protein (HSP) gene expression inhibitor produced by Streptomyces sp. AS-9. It can inhibit the expression of heat-induced luciferase reporter gene, and also inhibit the synthesis of heat-induced hsp72/73, hsp90 and hsp110. It has moderate cytotoxicity to tumor cell lines such as K562, PC6, HT29, and has antimicrobial activity against Micrococcus luteus, Staphylococcus aureus and Bacillus subtilis. Molecular formula: C11H13NO5. Mole weight: 239.22. | |
TMC-256A1 Quick inquiry Where to buy Suppliers range | TMC-256A1 is an inhibitor of IL-4 signal transduction isolated from the fermentation broth of Aspergillus niger var niger TC 1629. It inhibited the IL-4 driven luciferase activity with IC50 values of 25 μmol/L. Synonyms: TMC-256 A1. CAS No. 3773-18-0. Molecular formula: C15H12O5. Mole weight: 272.25. | |
TMC-256C1 Quick inquiry Where to buy Suppliers range | TMC-256C1 is an inhibitor of IL-4 signal transduction isolated from the fermentation broth of Aspergillus niger var niger TC 1629. It inhibited the IL-4 driven luciferase activity with IC50 values of 1.7 μmol/L. Synonyms: TMC-256 C1. Molecular formula: C15H12O5. Mole weight: 272.25. | |
TMC-260 Quick inquiry Where to buy Suppliers range | TMC-260 is an inhibitor of IL-4 signal transduction produced by Acremonium kiliense Grütz TC 1703. It inhibited the IL-4 driven luciferase activity with IC50 values of 9 μmol/L. Synonyms: TMC 260. Molecular formula: C17H27NO5. Mole weight: 325.4. | |
TMC-264 Quick inquiry Where to buy Suppliers range | TMC-264 is a STAT6 activation inhibitor produced by Phoma sp. TC 1674. It suppressed expression of IL-4 driven luciferase and germline Cepsilon mRNA with IC50 values of 0.3 and 0.4 μmol/L, respectively, and inhibited tyrosine phosphorylation of STAT6 with an IC50 value of 1.6 μmol/L. Synonyms: TMC 264. Molecular formula: C16H13ClO7. Mole weight: 352.72. | |
Trichodion Quick inquiry Where to buy Suppliers range | Trichodion is originally isolated from Trichosporiella sp. It inhibits the expression of secretion alkaline phosphatase (SEAP) Reporter gene mediated by IFN-V with IC50 of 5-10 μg/mL, and it also inhibits the expression of human IFN-α promoter-driven Luciferase Reporter gene with IC50 of 2.5-5μg/mL. Molecular formula: C12H14O5. Mole weight: 238.24. | |
Trichostatin RK Quick inquiry Where to buy Suppliers range | Trichostatin RK is a trigustatine derivative produced by the strain of Streptomyces sp. RK98-A74. It can induce luciferase, but its activity is lower than that of trigustatin. Molecular formula: C18H24N2O2. Mole weight: 300.39. | |
ZK 164015 Quick inquiry Where to buy Suppliers range | ZK 164015 is a potent estrogen receptor (ER) silent antagonist. ZK 164015 inhibits 17β-estradiol stimulation of luciferase activity (IC50 = 0.025 μM), and inhibits the growth of estrogen-sensitive human MCF-7 breast cancer cells in vitro (IC50 ~ 1 nM). Synonyms: ZK 164015; ZK164015; ZK-164015; 2-(4-Hydroxyphenyl)-3-methyl-1-[10-(pentylsulfonyl)decyl]-1H-indol-5-ol. Grades: ≥99% by HPLC. CAS No. 177583-70-9. Molecular formula: C30H43NO4S. Mole weight: 513.73. |