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MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 104676-09-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132251.
Mcc-555
Mcc-555. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-[[6-[(2-FLUOROPHENYL)METHOXY]-2-NAPHTHALENYL]METHYL]-2,4-THIAZOLIDINEDIONE;MCC-555;NETOGLITAZONE,2,4-THIAZOLIDINEDIONE, 5-[[6-[(2-FLUOROPHENYL)METHOXY]-2-NAPHTHALENYL]METHYL]-. Product Category: Heterocyclic Organic Compound. CAS No. 161600-01-7. Molecular formula: C21H16FNO3S. Mole weight: 381.42. Product ID: ACM161600017. Alfa Chemistry ISO 9001:2015 Certified. Categories: MBC-555.
MCC-555, a thiazolidinedion derivative, has been found to be a PPAR agonist that was once studied as hyperglycaemic and hyperlipidaemic. The Phase II trial against Type-2 diabetes mellitus has been already discontinued. Synonyms: Netoglitazone; MCC-555; MCC 555; MCC555; RWJ-241947; RWJ 241947; RWJ241947; isaglitazone; Netoglitazone; UNII-QOV2JZ647A; 5-[[6-[(2-fluorophenyl)methoxy]naphthalen-2-yl]methyl]-1,3-thiazolidine-2,4-dione. Grades: 98%. CAS No. 161600-01-7. Molecular formula: C21H16FNO3S. Mole weight: 381.42.
MCC950
MCC950, also called as CP-456773 or CRID3, is a small molecule that selectively inhibits activation of NLRP3 but does not inhibit NLRC4, AIM2, TLR2 signaling, or priming of NLRP3. MCC950 can be used to treat inflammatory diseases. Synonyms: MCC-950; MCC 950; CP-456773. CAS No. 210826-40-7. Molecular formula: C20H24N2O5S. Mole weight: 404.48.
MCC950
MCC950 (CP-456773; CRID3) is a potent and selective NLRP3 inhibitor with IC 50 s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-456773; CRID3. CAS No. 210826-40-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12815.
MCC950 sodium (CP-456773 sodium; CRID3 sodium salt) is a potent, selective NLRP3 inhibitor with IC 50 s of 7.5 and 8.1 nM in BMDMs and HMDMs, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-456773 sodium; CRID3 sodium salt. CAS No. 256373-96-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-12815A.
AceCel 101 (MCC 101)
AceCel 101 (MCC 101). Fine particle size, bulk-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, highly compressible. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for dietary supplement applications. Dosage Form: Tablet. Functionality: Binder, Carrier, Compaction, Diluent, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility, Wet Granulation. Process: Extrusion, Roller Compaction, Spheronization, Wet Granulation. Particle Size: 50 microns.
Sigachi US Inc
AceCel 102 (MCC 102)
AceCel 102 (MCC 102). Medium size particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines flow and high compactibility. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for dietary supplement applications. Dosage Form: Capsule, Powder,Tablet. Functionality: Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 90 microns.
Sigachi US Inc
AceCel 103 (Low moisture MCC 101)
AceCel 103 (Low moisture MCC 101). Low moisture (<3.0%) fine particle size, bulk-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, for processing moisture-sensitive active ingredients. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for dietary supplement applications. Dosage Form: Capsule. Functionality: Binder, Capsule Filling, Carrier, Compaction, Diluent, Dry Granulation, Filler, Moisture-Sensitive Active Ingredient, Natural Origin. Process: Capsule Filling, Roller Compaction, Dry Granulation. Particle Size: 50 microns.
Sigachi US Inc
AceCel 105 (MCC 105)
AceCel 105 (MCC 105). Extra fine particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, has a smooth texture and mouthfeel. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for dietary supplement applications. Dosage Form: Capsule, Multiple Dosage Forms, Orally Disintegrating Tablet, Semi-Solid, Tablet, Topical. Functionality: Binder, Capsule Filling, Carrier, Compaction, Diluent, Filler, Granulation, Multifunctional, Natural Origin, Tablet Compressibility, Wet Granulation. Process: Capsule Filling, Extrusion, Roller Compaction, Wet Granulation. Particle Size: 25 microns.
Sigachi US Inc
AceCel 112 (Low moisture MCC 102)
AceCel 112 (Low moisture MCC 102). Extra low moisture (<1.5%), high density, medium particle size spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines outstanding flow and good binding property for processing moisture-sensitive active ingredients. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for dietary supplement applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Capsule Filling, Carrier, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Moisture-Sensitive Active Ingredient, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 90 microns.
Sigachi US Inc
AceCel 113 (Low moisture MCC 101)
AceCel 113 (Low moisture MCC 101). Extra low moisture (<1.5%) fine particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, for processing moisture-sensitive active ingredients. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for dietary supplement applications. Dosage Form: Capsule. Functionality: Binder, Capsule Filling, Carrier, Compaction, Diluent, Filler, Moisture-Sensitive Active Ingredient, Natural Origin, Tablet Compressibility. Process: Capsule Filling, Extrusion, Roller Compaction, Spheronization. Particle Size: 50 microns.
Sigachi US Inc
AceCel 12 (MCC 12)
AceCel 12 (MCC 12). Coarse particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines good flow and high binding capacity. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for dietary supplement applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 150 microns.
Sigachi US Inc
AceCel 200 (MCC 200)
AceCel 200 (MCC 200). Large particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines outstanding flow and high binding capacity. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for dietary supplement applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 180 microns.
Sigachi US Inc
AceCel 301 (High BD MCC 101)
AceCel 301 (High BD MCC 101). Fine particle, high density spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines good flow and less volume. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for dietary supplement applications. Dosage Form: Capsule. Functionality: Capsule Filling, Carrier, Diluent, Filler, Natural Origin. Process: Capsule Filling. Particle Size: 50 microns.
Sigachi US Inc
AceCel 302 (High BD MCC 102)
AceCel 302 (High BD MCC 102). High density, medium particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines high flow and excellent binding property. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for dietary supplement applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Capsule Filling, Binder, Carrier, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Powder Blends, Natural Origin, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 90 microns.
Sigachi US Inc
HiCel 12 (MCC 12)
HiCel 12 (MCC 12). Coarse particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines good flow and high binding capacity. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 150 microns.
Sigachi US Inc
HiCel 14 (Low Moisture MCC 12)
HiCel 14 (Low Moisture MCC 12). Extra low moisture (<1.5%), coarse particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose for processing moisture-sensitive active ingredients. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Moisture-Sensitive Active Ingredient, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 150 microns.
Sigachi US Inc
HiCel 25M (MCC 105)
HiCel 25M (MCC 105). Extra fine particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, has a smooth texture and mouthfeel. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Multiple Dosage Forms, Orally Disintegrating Tablet, Semi-Solid, Tablet, Topical. Functionality: Binder, Capsule Filling, Carrier, Compaction, Diluent, Filler, Granulation, Multifunctional, Natural Origin, Tablet Compressibility, Wet Granulation. Process: Capsule Filling, Extrusion, Roller Compaction, Wet Granulation. Particle Size: 25 microns.
Sigachi US Inc
HiCel 50M (MCC 101)
HiCel 50M (MCC 101). Fine particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, highly compressible. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Tablet. Functionality: Binder, Carrier, Compaction, Diluent, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility, Wet Granulation. Process: Extrusion, Roller Compaction, Spheronization, Wet Granulation. Particle Size: 50 microns.
Sigachi US Inc
HiCel 90M (MCC 102)
HiCel 90M (MCC 102). Medium particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines flow and high compactibility. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 90 microns.
Sigachi US Inc
HiCel HD50M (High BD MCC 101)
HiCel HD50M (High BD MCC 101). Fine particle size, high density, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines good flow and less volume. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule. Functionality: Capsule Filling, Carrier, Diluent, Filler, Natural Origin. Process: Capsule Filling. Particle Size: 50 microns.
Sigachi US Inc
HiCel HD90M (High BD MCC 102)
HiCel HD90M (High BD MCC 102). High density, medium particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines high flow and excellent binding property. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Capsule Filling, Binder, Carrier, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Powder Blends, Natural Origin, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 90 microns.
Sigachi US Inc
HiCel LM50 (Low moisture MCC 101)
HiCel LM50 (Low moisture MCC 101). Extra low moisture (<1.5%), fine particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, for processing moisture-sensitive active ingredients. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule. Functionality: Binder, Capsule Filling, Carrier, Compaction, Diluent, Filler, Moisture-Sensitive Active Ingredient, Natural Origin, Tablet Compressibility. Process: Capsule Filling, Extrusion, Roller Compaction, Spheronization. Particle Size: 50 microns.
Sigachi US Inc
HiCel LP200 (MCC 200)
HiCel LP200 (MCC 200). Large particle size, spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines outstanding flow and high binding capacity. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Carrier, Capsule Filling, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 180 microns.
Sigachi US Inc
HiCel XLM 200 (Low moisture MCC 200)
HiCel XLM 200 (Low moisture MCC 200). Extra low moisture (<1.5%), high density, large particle size spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines outstanding flow and excellent binding property for processing moisture-sensitive active ingredients. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Capsule Filling, Carrier, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Moisture-Sensitive Active Ingredient, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Direct Compression, Dry Granulation. Particle Size: 180 microns.
Sigachi US Inc
HiCel XLM 90 (Low moisture MCC 102)
HiCel XLM 90 (Low moisture MCC 102). Extra low moisture (<1.5%), high density, medium particle size spray-dried microcrystalline cellulose is a purified, partly depolymerized cellulose, combines outstanding flow and good binding property for processing moisture-sensitive active ingredients. It is a white, odorless, tasteless, and free-flowing crystalline powder recommended for pharmaceutical applications. Dosage Form: Capsule, Powder, Tablet. Functionality: Binder, Capsule Filling, Carrier, Compaction, Diluent, Direct Compression, Dry Granulation, Filler, Granulation, Moisture-Sensitive Active Ingredient, Multifunctional, Natural Origin, Powder Blends, Tablet Compressibility. Process: Capsule Filling, Direct Compression, Dry Granulation. Particle Size: 90 microns.
Sigachi US Inc
MicroCrystalline Cellulose USP (MCC) 101 & 102
MicroCrystalline Cellulose USP (MCC) 101 & 102.
CA, FL & NJ
Moth Cytochrome C (MCC) 88-103
Moth Cytochrome C (MCC) 88-103, derived from the carboxyl terminus of moth cytochrome C, induces positive selection of TCR transgenic thymocytes. Synonyms: Ala-Asn-Glu-Arg-Ala-Asp-Leu-Ile-Ala-Tyr-Leu-Lys-Gln-Ala-Thr-Lys; L-alanyl-L-asparagyl-L-alpha-glutamyl-L-arginyl-L-alanyl-L-alpha-aspartyl-L-leucyl-L-isoleucyl-L-alanyl-L-tyrosyl-L-leucyl-L-lysyl-L-glutaminyl-L-alanyl-L-threonyl-L-lysine. Grades: ≥95%. CAS No. 108273-68-3. Molecular formula: C79H133N23O25. Mole weight: 1805.04.
POLYCOL- MCCI
POLYCOL- MCCI. Group: Polymers.
Vitamin K2 MK-7 1% on MCC
Vitamin K2 MK-7 1% on MCC.
CA, FL & NJ
Alamifovir
Alamifovir (LY582563; MCC-478), a purine nucleotide analogue proagent, shows potent activity against wild type and lamivudine resistant hepatitis B virus (HBV). Alamifovir has high activity against HBV replication and sustained antiviral effect [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY582563; MCC-478. CAS No. 193681-12-8. Pack Sizes: 1 mg. Product ID: HY-119691.
Alamifovir
Alamifovir (LY582563; MCC-478), a purine nucleotide analogue proagent, shows potent activity against wild type and lamivudine resistant hepatitis B virus (HBV). Alamifovir has high activity against HBV replication and sustained antiviral effect. Uses: Designed for use in research and industrial production. Additional or Alternative Names: alamifovir. Product Category: Inhibitors. CAS No. 193681-12-8. Molecular formula: C19H20F6N5O5PS. Mole weight: 575.425. Purity: 0.96. IUPACName: 9-[2-[bis(2,2,2-trifluoroethoxy)phosphorylmethoxy]ethyl]-6-phenylsulfanylpurin-2-amine. Canonical SMILES: COC1=CC=C(C=C1)SC2=C3N=CN(C3=NC(N)=N2)CCOCP(OCC(F)(F)F)(OCC(F)(F)F)=O. Density: 1.61g/cm³. Product ID: ACM193681128. Alfa Chemistry ISO 9001:2015 Certified.
CP-456773 sodium
CP-456773, also known as MCC950 and CRID3, is a potent, orally bioavailable NLRP3 inflammasome inhibitor and inhibits IL-1β (IC50 = 7.2 nM), IL-1α (IC50 = 12-18 nM) and IL-18 (IC50 = 10.3 nM) production for the treatment of inflammatory diseases. Synonyms: sodium ((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)((4-(2-hydroxypropan-2-yl)furan-2-yl)sulfonyl)amide; MCC950; MCC 950; MCC-950; CP-45677; CP45677; CP 45677; CRID-3; CRID3; CRID 3; CP-456773 sodium salt; CP 456773 sodium salt; CP456773 sodium salt; Cytokine release inhibitory drug 3. CAS No. 256373-96-3. Molecular formula: C20H24N2NaO5S. Mole weight: 427.46.
CYCLO(-HIS-PHE)
Cyclo(-His-Phe) is a catalyst for asymmetric cyanohydrin synthesis. In a study of McCleland et al., Cyclo(His-Phe) showed significant anti-tumour activity, causing reduction of cell viability in cervical cancer cells. Synonyms: 3-(5-Imidazolylmethyl)-6-benzylpiperazine-2,5-dione. CAS No. 56586-95-9. Molecular formula: C15H16N4O2. Mole weight: 284.31.
cystathionine β-synthase (O-acetyl-L-serine)
A pyridoxal 5'-phosphate protein. The enzyme, purified from the bacterium Bacillus subtilis, also has a low activity with L-serine (cf. EC 4.2.1.22, cystathionine β-synthase). Group: Enzymes. Synonyms: MccB; O-acetylserine dependent cystathionine β-synthase. Enzyme Commission Number: EC 2.5.1.134. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2750; cystathionine β-synthase (O-acetyl-L-serine); EC 2.5.1.134; MccB; O-acetylserine dependent cystathionine β-synthase. Cat No: EXWM-2750.
Emlenoflast
MCC7840 is a sulfonylurea non-steroidal anti-inflammatory drug and a potent selective inhibitor of NLRP3 inflammasome with IC50 <100 nM. Synonyms: N-[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl]-1-(propan-2-yl)-1H-pyrazole-3-sulfonamide; Inzomelid; 1H-Pyrazole-3-sulfonamide, N-(((1,2,3,5,6,7-hexahydro-S-indacen-4-yl)amino)carbonyl)-1-(1-methylethyl)-; N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-1-isopropyl-1H-pyrazole-3-sulfonamide; MCC7840. CAS No. 1995067-59-8. Molecular formula: C19H24N4O3S. Mole weight: 388.48.
INCB3344
INCB3344 is a potent CCR2 antagonist with IC50 of 5.1 nM and 9.5 nM for hCCR2 and mCCR2, respectively. Synonyms: INCB3344; INCB 3344; INCB-3344; N-(2-(((3S,4S)-1-(4-(Benzo[d][1,3]dioxol-5-yl)-4-hydroxycyclohexyl)-4-ethoxypyrrolidin-3-yl)amino)-2-oxoethyl)-3-(trifluoromethyl)benzamide. CAS No. 1262238-11-8. Molecular formula: C29H34F3N3O6. Mole weight: 577.59.
JNJ-41443532
JNJ-41443532 (CCR2 antagonist 5) is a selective, orally active hCCR2 inhibitor with good binding affinity ( IC 50 =37 nM) and potent functional antagonism ( chemotaxis IC 50 =30 nM). JNJ-41443532 displays a K i of 9.6 μM for mCCR2 binding. JNJ-41443532 can be used in the research of inflammatory disease [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CCR2 antagonist 5. CAS No. 1228650-83-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13499.
Karenitecin
Karenitecin, also known as Cositecan, is a synthetic silicon-containing agent related to camptothecin with antineoplastic properties. Karenitecin stabilizes the cleavable complex between topoisomerase I and DNA, resulting in DNA breaks and consequently triggering apoptosis. Because it is lipophilic, karenitecin exhibits enhanced tissue penetration and bio-availability compared to water-soluble camptothecins. Synonyms: Cositecan; BNP 1350; (4S)-4-Ethyl-4-hydroxy-11-[2-(trimethylsilyl)ethyl]-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 7-[2-(Trimethylsilyl)ethyl]camptothecin; DB 172; MCC 12824; (S)-4-ethyl-4-hydroxy-11-(2-(trimethylsilyl)ethyl)-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-11-[2-(trimethylsilyl)ethyl]-, (4S)-. Grades: ≥98%. CAS No. 203923-89-1. Molecular formula: C25H28N2O4Si. Mole weight: 448.59.
Malachite green hemioxalate
Malachite green hemioxalate (MCCK1) is a triphenylmethane dye which can be used to detect the release of phosphate in enzymatic reactions. Malachite green hemioxalate has antibacterial activity, which is attributed to inhibition of intracellular enzymes, insertion into DNA and/or interaction with cell membranes. Malachite green hemioxalate is also a potent and selective inhibitor of IKBKE , and inhibits its downstream targets such as IκBα , p65 and IRF3. Malachite green hemioxalate exhibits antitumor activity in vitro and in vivo [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: MCCK1. CAS No. 2437-29-8. Pack Sizes: 100 mg. Product ID: HY-D0162.
Microcin C7
Microcin C7 is an antibacterial peptide which is active against enterobacteria including species of Klebsiella, Salmonella, Shigella, Yersinia and Proteus, and strains of E.coli. Synonyms: MccC7.
Microcin H47
Microcin H47 (MccH47) is an antimicrobial peptide produced by some strains of Escherichia coli that has demonstrated inhibitory activity against enteric pathogens in vivo and has been heterologously overexpressed in proof-of-concept engineered probiotic applications. Synonyms: MccH47.
Microcin J25
The bacteriocin microcin J25 (MccJ25) inhibits the growth of Gram-negative pathogens including Salmonella and Shigella species, and Escherichia coli. Synonyms: MccJ25.
Microcrystalline cellulose NF
MCC. Grades: NF. CAS No. 9004-34-6. Product ID: 8-01133.
NAI-DMAC
NAI-DMAC. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-(4-Tert-butylphenyl)-1,8-naphthalimide-9,9-dimethyl-9,10-dihydroacridine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 2196247-08-0. Molecular formula: C37H32N2O2. Mole weight: 536.66 g/mol. Product ID: ACM2196247080. Alfa Chemistry ISO 9001:2015 Certified. Categories: Naida McCullough.
Netoglitazone
Netoglitazone is a dual agonist of PPARα and PPARγ with antihyperglycemic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCC-555; Isaglitazone. CAS No. 161600-01-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100428.
Trastuzumab emtansine
Trastuzumab emtansine is an antibody-drug conjugate (ADC) consisting of the recombinant anti-epidermal growth factor receptor 2 (HER2) monoclonal antibody trastuzumab conjugated to the maytansinoid DM1 via a nonreducible thioether linkage (MCC) with potential antineoplastic activity. The trastuzumab moiety of this ADC binds to HER2 on tumor cell surface surfaces. Upon internalization, the DM1 moiety is released and binds to tubulin, thereby disrupting microtubule assembly/disassembly dynamics and inhibiting cell division and the proliferation of cancer cells that overexpress HER2. Linkage of antibody and drug through a nonreducible linker has been reported to contribute to the improved efficacy and reduced toxicity of this ADC compared to similar ADCs constructed with reducible linkers. Grades: 95%. CAS No. 1018448-65-1. Molecular formula: C6448H9948N1720O2012S44· (C47H62ClN4O13S)n.
TRIS-VC
TRIS-VC. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-[Tris(trimethylsiloxy)silyl]propyl vinyl carbamate. Product Category: Other Monomers. CAS No. 134072-99-4. Molecular formula: C15H37NO5Si4. Mole weight: 423.8 g/mol. Purity: 0.94. Product ID: ACM-MO-134072994. Alfa Chemistry ISO 9001:2015 Certified. Categories: Tris McCall.
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