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| Product | Description | |
|---|---|---|
| Methyl 2,4-difluorobenzoate | Aryl Fluorinated Building Blocks. CAS No. 106614-28-2. Molecular formula: C8H6F2O2. Mole weight: 172.13. Catalog: ACM106614282. |  |
| Methyl-2,4-difluorobenzoate | Methyl-2,4-difluorobenzoate. CAS No: 106614-28-2 |  Sarchem Laboratories New Jersey NJ |
| Methyl 3-borono-2,6-difluorobenzoate | Heterocyclic Organic Compound. CAS No. 1190989-12-8. Molecular formula: C8H7BF2O4. Purity: 0.96. Catalog: ACM1190989128. | |
| Methyl 5-amino-2,4-difluorobenzoate | Heterocyclic Organic Compound. Alternative Names: 5-Amino-2,4-difluorobenzoic acid methyl ester;Methyl 5-amino-2,4-difluorobenzoate. CAS No. 125568-73-2. Molecular formula: C8H7F2NO2. Mole weight: 187.14. Purity: 0.98. Density: 1.355g/cm³. Catalog: ACM125568732. | |
| Methyl 5-bromo-2,3-difluorobenzoate | Heterocyclic Organic Compound. Alternative Names: METHYL 5-BROMO-2,3-DIFLUOROBENZOATE, 1150163-69-1, ACMC-2099ni, CTK4A9069, ANW-16780, AKOS015834359, Methyl 5-bromo-2,3-difluorobenzoate,, AG-D-35724, AK-98626, KB-54537, A-5086, I01-10895. CAS No. 1150163-69-1. Molecular formula: C8H5BrF2O2. Mole weight: 251.024906 [g/mol]. Purity: 0.96. IUPACName: methyl 5-bromo-2,3-difluorobenzoate. Canonical SMILES: COC(=O)C1=CC(=CC(=C1F)F)Br. Catalog: ACM1150163691. | |
| Baloxavir Impurity 45 | Baloxavir Impurity 45. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 2-(bromomethyl)-3,4-difluorobenzoate. Molecular Formula: C9H7BrF2O2. Mole Weight: 263.96. Catalog: APB02249. |  |
| Baloxavir Impurity 59 | Baloxavir Impurity 59. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 2-(dibromomethyl)-3,4-difluorobenzoate. Molecular Formula: C9H6Br2F2O2. Mole Weight: 343.95. Catalog: APB03934. | |
| Baloxavir Impurity 76 | Baloxavir Impurity 76. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 2-(bromomethyl)-4,5-difluorobenzoate. CAS No. 1245515-61-0. Molecular Formula: C9H7BrF2O2. Mole Weight: 265.05. Catalog: APB1245515610. | |
| 2,4-Difluorobenzoyl Risperidone Impurity | Risperidone impurity. Group: Biochemicals. Alternative Names: 3-[2-[4- (2, 4-Difluorobenzoyl) piperidin-1-yl]ethyl]-2-methyl-6, 7, 8, 9-tetrahydro-4H-pyrido[1, 2-a]pyrimidin-4-one; 3-[2-[4- (2, 4-Difluorobenzoyl) piperidino]ethyl]-6, 7, 8, 9-tetrahydro-2-methyl-4H-pyrido[1, 2-a]pyrimidin-4-one. Grades: Highly Purified. CAS No. 158697-67-7. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| 3-(6-{[1-(2,2-Difluorobenzo[1,3]dioxol-5-yl)-cyclopropanecarbonyl]-amino}-3-methyl-pyridin-2-yl)benzoic acid hydrochloride | Heterocyclic Organic Compound. CAS No. 1160221-26-0. Molecular formula: C24H18F2N2O5.HCl. Mole weight: 488.91. Catalog: ACM1160221260. | |
| 6-Methoxycarbonyl-2,2-difluorobenzo[d][1,3]dioxole-4-boronic acid,pinacol ester | Heterocyclic Organic Compound. Alternative Names: KB-45676, 6-Methoxycarbonyl-2,2-difluorobenzo[d][1,3]dioxole-4-boronic acid pinacol ester, 6-Methoxycarbonyl-2,2-difluorobenzo[d][1,3]dioxole-4-boronic acid, pinacol ester, 1150271-58-1. CAS No. 1150271-58-1. Molecular formula: C15H17BF2O6. Mole weight: 342.1. Purity: 0.98. IUPACName: methyl 2,2-difluoro-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,3-benzodioxole-5-carboxylate. Canonical SMILES: B1 (OC (C (O1) (C)C) (C)C)C2=CC (=CC3=C2OC (O3) (F)F)C (=O)OC. Catalog: ACM1150271581. | |
| AG-012917 | AG-012917 is a broad spectrum cyclin-dependent kinase inhibitor with potential anticancer activity. Synonyms: AG 012917; AG012917; (S)-4-((4-amino-5-(2,6-difluorobenzoyl)thiazol-2-yl)amino)-N-((1-methylpyrrolidin-2-yl)methyl)benzamide. Grades: >98%. CAS No. 486414-16-8. Molecular formula: C23H23F2N5O2S. Mole weight: 471.52. |  |
| AG-012986 | AG-012986 is a multitargeted cyclin-dependent kinase (CDK) inhibitor active against CDK1, CDK2, CDK4/6, CDK5, and CDK9, with selectivity over a diverse panel of non-CDK kinases. AG-012986 showed antiproliferative activities in vitro with IC(50)s of <100 nmol/L in 14 of 18 tumor cell lines. In vivo, significant antitumor efficacy induced by AG-012986 was seen (tumor growth inhibition,>83.1%) in 10 of 11 human xenograft tumor models. AG-012986 also showed dose-dependent retinoblastoma Ser(795) hypophosphorylation, cell cycle arrest, decreased Ki-67 tumor staining, and apoptosis in conjunction with antitumor activity. Synonyms: AG 012986; AG012986; Benzamide, 4-((4-amino-5-(2,6-difluorobenzoyl)-2-thiazolyl)amino)-N-((1R)-2-(dimethylamino)-1-methylethyl)-. Grades: >98%. CAS No. 486414-35-1. Molecular formula: C22H23F2N5O2S. Mole weight: 459.51. | |
| JNJ-42165279 | JNJ-42165279 is a fatty acid amide hydrolase (FAAH) inhibitor developed by Janssen Pharmaceutica and IC50 value is 70 nM. It is described as a covalently binding but slowly reversible selective inhibitor of FAAH. Phase II human trials for the treatment of anxiety disorders and major depressive disorder is on-going. Uses: Anxiety disorders and major depressive disorder. Synonyms: N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)methyl)piperazine-1-carboxamide; JNJ-42165279; JNJ 42165279; JNJ42165279. Grades: 98%. CAS No. 1346528-50-4. Molecular formula: C18H17ClF2N4O3. Mole weight: 410.81. | |
| Methyl 4-chloro-2-(2,6-difluorobenzamido)benzoate | Heterocyclic Organic Compound. CAS No. 1038343-13-3. Molecular formula: C15H10ClF2NO3. Mole weight: 325.694606;g/mol. Purity: 0.96. IUPACName: methyl4-chloro-2-[(2,6-difluorobenzoyl)amino]benzoate. Canonical SMILES: COC (=O)C1=C (C=C (C=C1)Cl)NC (=O)C2=C (C=CC=C2F)F. Catalog: ACM1038343133. | |
| Paliperidone Impurity I | An impurity of Paliperidone which is an active metabolite of RISPERIDONE and used as a second generation (atypical) antipsychotic agent. Synonyms: 3-(2-(4-(2,4-difluorobenzoyl)piperidin-1-yl)ethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one. Grades: > 95%. Molecular formula: C23H27F2N3O3. Mole weight: 431.49. | |
| Pyrrophenone | Pyrrophenone is an inhibitor of cytosolic phospholipase A2α (cPLA2α) with an IC50 of 4.2 nM in enzyme assays. It potently inhibited arachidonic acid release in calcium ionophore (A23187)-stimulated human monocytic cells (THP-1 cells) in a dose-dependent manner with IC50 value of 0.024 mM. Synonyms: N-[[(2S,4R)-1-[2-(2,4-Difluorobenzoyl)benzoyl]-4-tritylsulfanylpyrrolidin-2-yl]methyl]-4-[(E)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]benzamide. Grades: ≥95%. CAS No. 341973-06-6. Molecular formula: C49H37F2N3O5S2. Mole weight: 850. | |
| Risperidone Impurity H | An impurirty of Risperidone,Risperidone is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist. Synonyms: 3-[2-[4-(2,4-Difluorobenzoyl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one; 3-[2-[4-(2,4-Difluorobenzoyl)piperidino]ethyl]-6,7,8,9- tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one. Grades: > 95%. CAS No. 158697-67-7. Molecular formula: C23H27F2N3O2. Mole weight: 415.49. | |
| RSC-3388 | RSC-3388 is a potent inhibitor of cPLA2&alpha. It exhibited potent inhibitory effect against skin inflammation in mice. Synonyms: N-[[1-[2-(2,4-difluorobenzoyl)benzoyl]-4-[2-methylpropyl-[(2-phenylphenyl)methyl]amino]pyrrolidin-2-yl]methyl]-3-[4-[(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]phenyl]prop-2-enamide. Grades: ≥95%. CAS No. 337307-06-9. Molecular formula: C49H44F2N4O5S. Mole weight: 839. | |
| Zegocractin | Zegocractin, also known as CM4620, is a selective Orai1 inhibitor, prevents Ca2+ entry in acinar cells. The intravenous administration of CM4620 reduces the severity of acute pancreatitis in the rat, a hitherto untested species. SOCE via STIM1/Orai complexes promotes activation and fibroinflammatory gene expression within pancreatic stellate cells. CM4620 also decreased myeloperoxidase activity and inflammatory cytokine expression in pancreas and lung tissues, fMLF peptide-induced oxidative burst in human neutrophils, and cytokine production in human peripheral blood mononuclear cells (PBMCs) and rodent PaSCs, indicating that Orai1/STIM1 channels participate in the inflammatory responses of these cell types during acute pancreatitis. Group: Inhibitors. Alternative Names: CM-4620; CM 4620; CM4620; Zegocractin. CAS No. 1713240-67-5. Molecular formula: C19H11ClF3N3O3. Mole weight: 421.76. Appearance: Solid powder. Purity: >98%. IUPACName: N-(5-(6-chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)pyrazin-2-yl)-2-fluoro-6-methylbenzamide. Canonical SMILES: O=C (NC1=NC=C (C2=C (Cl)C=C (OC (F) (F)O3)C3=C2)N=C1)C4=C (C)C=CC=C4F. Catalog: ACM1713240675. | |
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