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Methyl indole-3-carboxylate is a natural product isolated from Sorangium cellulosum strain Soce895. Methyl indole-3-carboxylate shows a weak activity against the Gram-positive Nocardia sp with a MIC value of 33.33 μg/mL [1]. Uses: Scientific research. Group: Natural products. CAS No. 942-24-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-79635.
An intermediate in the synthesis of Tadafil, which is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
An intermediate in the synthesis of Tadafil, which is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
2-[(3-Chlorophenyl)methyl]-5-hydroxy-1H-benz[g]indole-3-carboxylic acid,ethyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SureCN530099, CHEMBL490461, CTK8E3590, MolPort-009-019-576, CAY10606, ZINC40422668, 5-hydroxy-1H-benzo[g]indole-3-carboxylate, 11a, 2-[(3-chlorophenyl)methyl]-5-hydroxy-1H-benz[g]indole-3-carboxylic acid, ethyl ester, 1159576-98-3. Product Category: Heterocyclic Organic Compound. CAS No. 1159576-98-3. Molecular formula: C22H18ClNO3. Mole weight: 379.836220 [g/mol]. Purity: 0.96. IUPACName: ethyl 2-[(3-chlorophenyl)methyl]-5-hydroxy-1H-benzo[g]indole-3-carboxylate. Canonical SMILES: CCOC(=O)C1=C(NC2=C1C=C(C3=CC=CC=C32)O)CC4=CC(=CC=C4)Cl. Product ID: ACM1159576983. Alfa Chemistry ISO 9001:2015 Certified.
Arbidol hydrochloride
Arbidol hydrochloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-Bromo-4-(dimethylaminomethyl)-5-hydroxy-1-methyl-2-[(phenylthio)methyl]indole-3-carboxylic acid ethyl ester hydrate hydrochloride. Appearance: Solid. CAS No. 131707-23-8. Molecular formula: C22H26BrClN2O3S. Mole weight: 513.88. Purity: 0.98. IUPACName: ethyl 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-(phenylsulfanylmethyl)indole-3-carboxylate;hydrochloride. Canonical SMILES: CCOC(=O)C1=C(N(C2=CC(=C(C(=C21)CN(C)C)O)Br)C)CSC3=CC=CC=C3.Cl. Product ID: ACM131707238. Alfa Chemistry ISO 9001:2015 Certified.
Indole-3-carboxylic acid methyl ester
Indole-3-carboxylic acid methyl ester. Group: Biochemicals. Alternative Names: methyl indole-3-carboxylate. Grades: Highly Purified. CAS No. 942-24-5. Pack Sizes: 25g, 50g, 100g. Molecular Formula: C10H9NO2. US Biological Life Sciences.
One of the impurities of Tadalafil, which is an inhibitor of phosphodiesterase 5 and could be used in the treatmen of erectile dysfunction. Synonyms: (1R,3R)-Methyl-1-(Benzo[d][1,3]dioxol-5-yl)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro- 1H-pyrido[3,4-b]indole-3-carboxylate. Grades: > 95%. CAS No. 951661-84-0. Molecular formula: C22H20ClN3O4. Mole weight: 425.88.
Tadalafil derivative. Used in the preparation of pyrazinopyridoindole derivatives for their PDE5 inhibitory activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 171596-44-4. Pack Sizes: 25mg. US Biological Life Sciences.
Tadalafil derivative. Used in the preparation of pyrazinopyridoindole derivatives for their PDE5 inhibitory activity. Group: Biochemicals. Alternative Names: (1S-cis)-1-(1,3-benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester. Grades: Highly Purified. CAS No. 171596-43-3. Pack Sizes: 25mg. US Biological Life Sciences.
2,3-Dihydro-1H-indole-3-carboxylic acid methyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 528862-00-2, 2,3-Dihydro-indole-1,3-dicarboxylic acid 1-tert-butyl ester 3-methyl ester, SureCN3695799, AB1512, AK-49860, KB-67302, METHYL 1-BOC-INDOLINE-3-CARBOXYLATE, D57236, 1-tert-Butyl 3-methyl indoline-1,3-dicarboxylate. Product Category: Heterocyclic Organic Compound. CAS No. 528862-00-2. Molecular formula: C10H11NO2. Mole weight: 177.2. Purity: 0.96. IUPACName: 1-O-tert-butyl 3-O-methyl 2,3-dihydroindole-1,3-dicarboxylate. Canonical SMILES: CC(C)(C)OC(=O)N1CC(C2=CC=CC=C21)C(=O)OC. Product ID: ACM528862002. Alfa Chemistry ISO 9001:2015 Certified. Categories: methyl indoline-3-carboxylate.
Abecarnil
Abecarnil is a beta carboline and a partial benzodiazepine-receptor agonist that has demonstrated promise as an anxiolytic agent. It may be useful in treating generalized anxiety disorder. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Abecarnil; ZK 112119; ZK-112119; ZK112119. Product Category: Agonists. Appearance: Solid powder. CAS No. 111841-85-1. Molecular formula: C24H24N2O4. Mole weight: 404.47. Purity: >98%. IUPACName: 6-(Benzyloxy)-4-(methoxymethyl)-9H-pyrido[3,4-b]indole-3-carboxylic acid 1-methylethyl ester. Canonical SMILES: O=C(C1=C(COC)C2=C(C=N1)NC3=C2C=C(OCC4=CC=CC=C4)C=C3)OC(C)C. Product ID: ACM111841851. Alfa Chemistry ISO 9001:2015 Certified.
cis-Ned 19
cis-Ned 19 is a irreversible nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist, which inhibits Ca2+ release (IC50 = 800 nM) and [32P]NAADP binding (IC50 = 15 μM). Ned-19 has two diastereomers, the 'trans' and 'cis', the trans form was more potent than the cis form in regard to both inhibition of Ca2+ release (IC50 of 6 nM versus 800 nM) and [32P]NAADP binding (IC50 of 0.4 nM versus 15 μM). Synonyms: cis-Ned 19; cis-Ned19; cis-Ned-19; (1S,3S)-1-[3-[[4-(2-Fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid. Grades: ≥97% by HPLC. CAS No. 1137264-00-6. Molecular formula: C30H31FN4O3. Mole weight: 514.59.
cis-Ned-19 Methyl Ester
cis-Ned-19 Methyl Ester is a side product produced during the preparation of trans-Ned-19 (N388750), a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. Group: Biochemicals. Alternative Names: (1R,3R)-1-[3-[[4-(2-Fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
DMCM hydrochloride
DMCM hydrochloride, a negative allosteric modulator of GABAA receptors, is a benzodiazepine inverse agonist with strong anxiogenic and convulsant properties. Synonyms: 9H-Pyrido[3,4-b]indole-3-carboxylic acid, 4-ethyl-6,7-dimethoxy-, methyl ester, hydrochloride (1:1); 4-Ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester hydrochloride; 6,7-Dimethoxy-4-ethyl-β-carboline-3-carboxylic acid methyl ester hydrochloride; Methyl 6,7-dimethoxy-4-ethyl-β-carboline-3-carboxylate hydrochloride. Grades: ≥98% by HPLC. CAS No. 1215833-62-7. Molecular formula: C17H18N2O4.HCl. Mole weight: 350.80.
Indole-3-CarboxylicAcid
Indole-3-CarboxylicAcid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-INDOLECARBOXYLIC ACID:INDOLE-3-CARBOXYLIC ACID;3-INDOLECARBOXYLIC ACID:INDOLE-3-CARBOXYLIC ACID, 99+%. Product Category: Heterocyclic Organic Compound. CAS No. 711-50-6. Molecular formula: C9H6O2N. Mole weight: 196.157. Purity: 0.96. IUPACName: 2-hydroxy-6-methylterephthalic acid. Product ID: ACM711506. Alfa Chemistry ISO 9001:2015 Certified.
Lavendamycin
It is produced by the strain of Str. lavendulae C-22030. It's a quinone antibiotic. It has anti-bacterial and fungal effect, but the anti-bacterial effect is weaker than Streptonigrin, while the anti-fungal effect is stronger than Streptonigrin. Synonyms: 9H-Pyrido(3,4-b)indole-3-carboxylic acid, 1-(7-amino-5,8-dihydro-5,8-dioxo-2-quinolinyl)-4-methyl-; Antibiotic K 82A. CAS No. 81645-09-2. Molecular formula: C22H14N4O4. Mole weight: 398.38.
Ned-K
Ned-K, a nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist, effectively inhibits Ca2+ oscillations induced by simulated ischemia and reperfusion (sIR) in cardiomyocytes. Synonyms: 1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-[3-[[4-(2-cyanophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-, (1R,3S)-; (1R,3S)-1-(3-{[4-(2-Cyanophenyl)-1-piperazinyl]methyl}-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-β-carboline-3-carboxylic acid. CAS No. 2250019-90-8. Molecular formula: C31H31N5O3. Mole weight: 521.61.
Tadalafil Related Impuirty 5
One of the impurities of Tadalafil, which is an inhibitor of phosphodiesterase 5 and could be used in the treatmen of erectile dysfunction. Synonyms: (1R,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester. Grades: > 95%. CAS No. 171596-44-4. Molecular formula: C20H18N2O4. Mole weight: 350.38.
Tadalafil Related Impuirty 6
One of the impurities of Tadalafil, which is an inhibitor of phosphodiesterase 5 and could be used in the treatmen of erectile dysfunction. Synonyms: (1S,3S)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid Methyl Ester. Grades: > 95%. CAS No. 171596-43-3. Molecular formula: C20H18N2O4. Mole weight: 350.38.
trans-Ned 19
trans-Ned 19, a structural analog of NAADP, is a nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist.trans-Ned 19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM), and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). It can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells. Synonyms: (1R,3S)-1-[3-[[4-(2-Fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid; Ned-19; Ned 19; Ned19. Grades: ≥98% by HPLC. CAS No. 1354235-96-3. Molecular formula: C30H31FN4O3. Mole weight: 514.59.
trans-Ned-19
trans-Ned-19 is a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells. Group: Biochemicals. Alternative Names: (1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid. Grades: Highly Purified. CAS No. 1354235-96-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
trans-Ned-19 Methyl Ester
trans-Ned-19 Methyl Ester is a trans-Ned-19 (N388750) derivative, a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. Group: Biochemicals. Alternative Names: (1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic Acid. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
ZK 93426 hydrochloride
ZK 93426 hydrochloride is a potent, selective and competitive benzodiazepine receptor antagonist (IC50 = 0.4 and 0.7 nM for inhibition of [3H]-flunitrazepam binding to rat cerebellum and hippocampus, respectively). ZK 93426 hydrochloride displays both anxiogenic and anxiolytic effects. Synonyms: ZK 93426 monohydrochloride; ZK93426 hydrochloride; ZK-93426 hydrochloride; 4-Methyl-5-(1-methylethoxy)-9H-pyrido[3,4-b]indole-3-carboxylic acid ethyl ester hydrochloride; 9H-Pyrido[3,4-b]indole-3-carboxylic acid, 4-methyl-5-(1-methylethoxy)-, ethyl ester, hydrochloride (1:1). Grades: ≥99% by HPLC. CAS No. 1216792-30-1. Molecular formula: C18H20N2O3.HCl. Mole weight: 348.82.
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