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| Product | Description | |
|---|---|---|
| 1,2,3,4-Tetrahydro-1-methyl-6-quinolinemethanol | 1,2,3,4-Tetrahydro-1-methyl-6-quinolinemethanol. Group: Biochemicals. Alternative Names: 6-(Chloromethyl)-1-methyl-1,2,3,4-tetrahydroquinoline. Grades: Highly Purified. CAS No. 68031-99-2. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C11H15NO. US Biological Life Sciences. |  Worldwide |
| 1,2,3,4-Tetrahydro-2-oxo-3-quinolineacetic Acid Methyl Ester | 1,2,3,4-Tetrahydro-2-oxo-3-quinolineacetic Acid Methyl Ester is used in the synthesis of 1H-2,3,3a,4-tetrahydro-2-oxopyrrolo[2,3-b]quinolines which possess hypotensive properties with up to 34% decrease in aortic blood pressure after 30 minutes when administered to rats. It is also used as a reagent in the preparation of bicyclic compounds and compositions as PDF inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 61164-72-5. Pack Sizes: 100mg, 1g. Molecular Formula: C12H13NO3, Molecular Weight: 219.24. US Biological Life Sciences. | Worldwide |
| 1-Methyl-7-nitro-1,2,3,4-tetrahydro quinoline | 1-Methyl-7-nitro-1,2,3,4-tetrahydro quinoline. Group: Biochemicals. Grades: Highly Purified. CAS No. 39275-18-8. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C10H12N2O2. US Biological Life Sciences. | Worldwide |
| (2R)-1-(11bR)-(Dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)-2-methyl-1,2,3,4-tetrahydroquinoline | Phosphine Ligands. Alternative Names: (R,Ra)-Me-THQphos. CAS No. 1186392-43-7. Molecular formula: C30H24NO2P. Mole weight: 461.49. Appearance: Solid. Purity: 98%+. IUPACName: (2R)-1-(12, 14-dioxa-13-phosphapentacyclo[13.8.0.02, 11.03, 8.018, 23]tricosa-1(15), 2(11), 3, 5, 7, 9, 16, 18, 20, 22-decaen-13-yl)-2-methyl-3, 4-dihydro-2H-quinoline. Catalog: ACM1186392437. |  |
| 6-Fluoro-1,2,3,4-tetrahydro-2-methylquinoline | Intermediate in the production of anti-cancer quinoline derivatives and antibacterial agents. Group: Biochemicals. Alternative Names: 1,2,3,4-Tetrahydro-6-fluoro-2-methylquinoline; 6-Fluoro-2-methyl-1,2,3,4-tetrahydroquinoline. Grades: Highly Purified. CAS No. 42835-89-2. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 6-Hydroxy-1,2,3,4-tetrahydroquinoline-2-carboxylic acid methyl ester | Heterocyclic Organic Compound. Alternative Names: 6-Hydroxy-1,2,3,4-tetrahydro-quinoline-2-carboxylic acid methyl ester. CAS No. 1219397-09-7. Molecular formula: C11H13NO3. Mole weight: 207.22582;g/mol. Purity: 0.96. IUPACName: methyl6-hydroxy-1,2,3,4-tetrahydroquinoline-2-carboxylate. Canonical SMILES: COC(=O)C1CCC2=C(N1)C=CC(=C2)O. Catalog: ACM1219397097. | |
| (6R, 12bR)-6-(1, 3-Benzodioxol-5-yl)-2, 3, 7, 12b-tetrahydro-2-methyl-pyrazino[1', 2':1, 5]pyrrolo[3, 4-b]quinoline-1, 4, 12(6H)-trione | (6R, 12bR)-6-(1, 3-Benzodioxol-5-yl)-2, 3, 7, 12b-tetrahydro-2-methyl-pyrazino[1', 2':1, 5]pyrrolo[3, 4-b]quinoline-1, 4, 12(6H)-trione. Group: Biochemicals. Grades: Highly Purified. CAS No. 531500-51-3. Pack Sizes: 5mg. Molecular Formula: C22H17N3O5, Molecular Weight: 403.39. US Biological Life Sciences. | Worldwide |
| (6S, 12bR)-6-(1, 3-Benzodioxol-5-yl)-2, 3, 7, 12b-tetrahydro-2-methyl-pyrazino[1', 2':1, 5]pyrrolo[3, 4-b]quinoline-1, 4, 12(6H)-trione | (6S, 12bR)-6-(1, 3-Benzodioxol-5-yl)-2, 3, 7, 12b-tetrahydro-2-methyl-pyrazino[1', 2':1, 5]pyrrolo[3, 4-b]quinoline-1, 4, 12(6H)-trione. Group: Biochemicals. Grades: Highly Purified. CAS No. 531500-48-8. Pack Sizes: 2.5mg. Molecular Formula: C22H17N3O5, Molecular Weight: 403.39. US Biological Life Sciences. | Worldwide |
| 1, 2, 3, 4-Tetra hydro-1-phenyl-6-quinolinecarboxalde hydediphenyl hydrazon | Heterocyclic Organic Compound. Alternative Names: 1, 2, 3, 4-Tetra hydro-1-phenyl-6-quinolinecarboxalde hydediphenyl hydrazon; 1, 2, 3, 4-TETRA hydRO-1-PHENYL-6-QUINOLINECARBOXALDE hydE DIPHENYLHYDRAZONE;1,2,3,4-Tetrahydro-1-phenyl-6-[(2,2-diphenylhydrazono)methyl]quinoline;1-Phenyl-1,2,3,4-tetrahydroquinoline-6-ca. CAS No. 100070-43-7. Molecular formula: C28H25N3. Mole weight: 403.5182. Catalog: ACM100070437. | |
| 2-((2,5-dimethylphenyl)(p-tolyl)methyl)-1,4-dimethylbenzene | Heterocyclic Organic Compound. Alternative Names: 7, 8, 17, 18-tetrahydrodibenzo- | |
| 6-Chloro-2-hydroxy-quinoline-4-carboxylic acid | Heterocyclic Organic Compound. Alternative Names: Pyrindamycin B, duocarmycin C1, Antibiotic DC 89A1, C26H26ClN3O8, DC89-A1, DC 89-A1, BRN 5689373, CID133973, LS-21000, LS-139683, 1H-Pyrrolo(3,2-f)quinoline-2-carboxylic acid, 8-chloro-2,3,6,7,8,9-hexahydro-4-hydroxy-2-methyl-oxo-6-((5,6,7-trimethoxy-1H-indol-2-yl)carbonyl)-, methyl ester, 113189-05-2, 118292-35-6, 1H-Pyrrolo(3,2-f)quinoline-2-carboxylic acid, 8-chloro-2,3,6,7,8,9-hexahydro-4-hydroxy-2-methyl-1-oxo-6-((5,6,7-trimethoxy-1H-indol-2-yl)carbonyl)-, methyl ester. CAS No. 118292-35-6. Molecular formula: C10H6ClNO3. Mole weight: 223.61. Purity: 0.96. IUPACName: methyl (2R,8S)-8-chloro-4-hydroxy-7-methyl-1-oxo-6-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-3,7,8,9-tetrahydro-2H-pyrrolo[3,2-f]quinoline-2-carboxylate. Canonical SMILES: C1=CC2=C(C=C1Cl)C(=CC(=O)N2)C(=O)O. Catalog: ACM118292356. | |
| Boldine | Boldine. Group: Biochemicals. Alternative Names: NSC 65689; Boldin; Boldina; d-?Boldine; (+)-(S)-Boldine; (+)-2,9-Dihydroxy-1,10-dimethoxyaporphine; (+)-Boldine; (S)-(+)-Boldine; (6aS)-5,6,6a,7-tetrahydro-1,10-dimethoxy-6-methyl-4H-Dibenzo[de,g]quinoline-2,9-diol. Grades: Highly Purified. CAS No. 476-70-0. Pack Sizes: 1g. Molecular Formula: C19H21NO4, Molecular Weight: 327.37. US Biological Life Sciences. | Worldwide |
| boldine EP Impurity A | boldine EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (6S,6aS)-2,9-dihydroxy-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline N-oxide. Molecular Formula: C19H21NO5. Mole Weight: 343.37. Catalog: APB03761. |  |
| boldine EP Impurity B | boldine EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (6R,6aS)-2,9-dihydroxy-1,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline N-oxide. Molecular Formula: C19H21NO6. Mole Weight: 343.38. Catalog: APB03760. | |
| BRD 6989 | BRD 6989 is a small molecule inhibitor with high selectivity for CDK8 over CDK19. It is an analog of the natural product cortistatin A (dCA), which inhibits CDK8 and upregulates IL-10. BRD 6989 selectively binds a complex of CDK8 with an IC50 of 200 nM. It also inhibits IFNγ-induced phosphorylation of STAT1 at Ser 727 site in BMDCs. It may be useful for inflammatory disorders. Synonyms: 2-Amino-5,6,7,8-tetrahydro-6-methyl-4-(3-pyridinyl)-3-quinolinecarbonitrile; BRD-6989; BRD6989. Grades: ≥98%. CAS No. 642008-81-9. Molecular formula: C16H16N4. Mole weight: 264.33. |  |
| Corytuberine | Corytuberine. Group: Biochemicals. Alternative Names: (6aS)-5,6,6a,7-Tetrahydro-2,10-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-1,11-diol; 2,10-Dimethoxy-6a-a-aporphine-1,11-diol; (+)-Corytuberine. Grades: Highly Purified. CAS No. 517-56-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C19H21NO4. US Biological Life Sciences. | Worldwide |
| Elomotecan HCl salt | Elomotecan, also referred to BN 80927 and R 1559, characterized by a stable seven-membered beta-hydroxylactone ring, is a DNA topoisomerase inhibitor. In vivo elomotecan shows high efficiency in vivo in tumor xenograft studies using human androgen-independent prostate tumors PC3 and DU145. Synonyms: 220997-99-9; 220998-10-7 (Elomotecan free base); (5R)-9-chloro-5-ethyl-5-hydroxy-10-methyl-12-[(4-methylpiperidin-1-yl)methyl]-1,4,5,13-tetrahydro-3H,15H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione hydrochloride (1:1). Grades: >98%. CAS No. 220997-99-9. Molecular formula: C29H33Cl2N3O4. Mole weight: 558.5. | |
| FIBROBLAST GROWTH FACTOR, BASIC*FRAGMENT106-120 AC | Heterocyclic Organic Compound. CAS No. 114752-18-0. Molecular formula: C29H30N2O8. Mole weight: 534.5571;g/mol. Purity: 0.96. IUPACName: butan-2-yl7-(4-methoxyphenyl)-2-methyl-4-(6-nitro-1,3-benzodioxol-5-yl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carboxylate. Canonical SMILES: CCC (C)OC (=O)C1=C (NC2=C (C1C3=CC4=C (C=C3[N+] (=O)[O-])OCO4)C (=O)CC (C2)C5=CC=C (C=C5)OC)C. Catalog: ACM114752180. | |
| G-36 | G-36 is an antagonist of G protein-coupled estrogen receptor (GPER). It selectively inhibits estrogen-mediated activation of PI3-K by GPER and estrogen-mediated calcium mobilization (IC50 = 112 nM). Synonyms: GRB-G36; G-36; G36; G 36. (±)-(3aR,4S,9bS)-4-(6-Bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-8-(1-methylethyl)-3H-cyclopenta[c]quinoline. Grades: ≥99% by HPLC. CAS No. 1392487-51-2. Molecular formula: C22H22BrNO2. Mole weight: 412.33. | |
| Gimatecan | Gimatecan is an orally bioavailable, semi-synthetic lipophilic analogue of camptothecin, a quinoline alkaloid extracted from the Asian tree Camptotheca acuminate, with potential antineoplastic and antiangiogenic activities. Gimatecan binds to and inhibits the activity of topoisomerase I, stabilizing the cleavable complex of topoisomerase I-DNA, which inhibits the religation of single-stranded DNA breaks generated by topoisomerase I; lethal double-stranded DNA breaks occur when the topoisomerase I-DNA complex is encountered by the DNA replication machinery, DNA replication is disrupted, and the tumor cell undergoes apoptosis. Although the mechanism of its antiangiogenic activity has yet to be full elucidated, this agent may inhibit endothelial cell migration, tumor neovascularization, and the expression of proangiogenic basic fibroblast growth factor (bFGF). Synonyms: ST1481; 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-11-carboxaldehyde, 4-ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-, 11-(O-(1,1-dimethylethyl)oxime), (C(E),4S)-; 7-t-Butoxyiminomethylcamptothecin; (4S)-11-((E)-((1,1-DImethylethoxy)imino)methyl)-4-ethyl-4-hydroxy-1,12-dihydro-14H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H)-dione; NSC793724. Grades: ≥98%. CAS No. 292618-32-7. Molecular formula: C25H25N3O5. Mole weight: 447.48. | |
| Isoboldine | Isoboldine. Group: Biochemicals. Alternative Names: (6aS)-5,6,6a,7-Tetrahydro-2,10-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-1,9-diol. Grades: Highly Purified. CAS No. 3019-51-0. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C19H21NO4. US Biological Life Sciences. | Worldwide |
| (+)-ITD-1 | (+)-ITD-1 is the (+)-enantiomer of ITD 1 that is more active. ITD-1 is a selective inhibitor of TGFβ/Smad signaling (IC50 values 0.46 μM and 6.90 μM for (+)-ITD 1 and (-)-ITD 1, respectively for TGF-β inhibition) that clears the type II TGFβ receptor from the cell surface. ITD 1 promotes the differentiation of cardiomyocytes and cardiogenesis in murine embryonic stem cell (mESCs). Synonyms: ITD-1; 1099644-42-4; ITD 1; ITD1; ethyl 2,7,7-trimethyl-5-oxo-4-(4-phenylphenyl)-1,4,6,8-tetrahydroquinoline-3-carboxylate; (+)-ITD 1; 1409968-46-2; 4-[1,1'-Biphenyl]-4-yl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxo-3-quinolinecarboxylic acid ethyl ester; Ethyl 4-([1,1'-biphenyl]-4-yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate; ethyl 4-(biphenyl-4-yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate;6-{(1R)-1-[8-Fluoro-6-(1-methyl-1H-pyrazol-4-yl)[1,2,4]triazolo[4,3-a]pyridin-3-yl]ethyl}-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H) -one; ethyl 2,7,7-trimethyl-5-oxo-4-(4-phenylphenyl)-1,4,5,6,7,8-hexahydro-3-quinolinecarboxylate; ethyl 2,7,7-trimethyl-5-oxo-4-(4-phenylphenyl)-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate. Grades: 99%. CAS No. 1409968-46-2. Molecular formula: C27H29NO3. Mole weight: 415.52. | |
| JNJ26076713 | JNJ26076713 is an orally active alpha V integrin antagonist. It may be a potential therapeutic candidate for the treatment of age-related macular degeneration,proliferative diabetic retinopathy and macular edema. Uses: Jnj26076713 may be a potential therapeutic candidate for the treatment of age-related macular degeneration,proliferative diabetic retinopathy and macular edema. Synonyms: JNJ-26076713; JNJ26076713; JNJ 26076713;3-Quinolinepropanoic acid, 1,2,3,4-tetrahydro-beta-((1-(1-oxo-3-(1,5,6,7-tetrahydro-1,8-naphthyridin-2-yl)propyl)-4-piperidinyl)methyl)-, (betaS,3S)-;(3S)-4-[1-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propanoyl]piperidin-4-yl]-3-[(3S)-1,2. Grades: 98%. CAS No. 669076-03-3. Molecular formula: C29H38N4O3. Mole weight: 490.65. | |
| L-Dicentrine | A natural vascular alpha 1-adrenoceptor antagonist but less prevalent than the D-isomer. It markedly inhibits the contraction of rat stomach muscle strips induced by 5-HT, histamine, K+ and Ca2+ after high K+ depolarization, showing a non-competitive antagonism and could be a potential muscle relaxant. Studies suggest that it has protective effect of on acute myocardial Iichemia and anoxia lesion. Group: Biochemicals. Alternative Names: (7aR)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline; 9,10-Dimethoxy-1,2-(methylenedioxy)-6a β-aporphine; (R)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline; (-)-Dicentrine; (R)-(-)-Dicentrine; NSC 251699. Grades: Highly Purified. CAS No. 28832-07-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| L-Dicentrine-d3 | L-Dicentrine-d3. Group: Biochemicals. Alternative Names: (7aR)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline-d3; 9,10-Dimethoxy-1,2-(methylenedioxy)-6a β-aporphine-d3; (R)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline-d3; (-)-Dicentrine-d3; (R)-(-)-Dicentrine-d3; NSC 251699-d3. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C20H18D3NO4, Molecular Weight: 342.4. US Biological Life Sciences. | Worldwide |
| Lisuride maleate | Lisuride maleate, an ergot derivative, is a nonselective dopamine receptor agonist with high affinity for D2, D3 and D4 receptors along with 5-HT1A. As an anti-Parkinson's agent with anticonvulsive effects, Lisuride maleate has been shown to decrease the release of prolactin and reduce inflammatory mediators such as IL6 and TNF-&alpha. Synonyms: 3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinoline-9-yl]-1,1-diethylurea;(Z)-but-2-enedioic acid; Lisuride Maleate ; Cuvalit; Lysenyl; Lysenyl bimaleate; Lysenyl hydrogen maleate; Lisuride hydrogen maleate; Mesylate, Lisuride; Methylergol ;Carbamide Revanil. Grades: >99 %. CAS No. 19875-60-6. Molecular formula: C25H31N3O5. Mole weight: 454.58. | |
| Methoxyadiantifoline | Other Alkaloids. Alternative Names: (6aS)-9-[4, 5-Dimethoxy-2-[[[(1S)-1β , 2, 3, 4-tetrahydro-5, 6, 7-trimethoxy-2-methylisoquinolin]-1α -yl]methyl]phenoxy]-5, 6, 6aα , 7-tetrahydro-1, 2, 3, 10-tetramethoxy-6-methyl-4H-dibenzo[de, g]quinoline. CAS No. 115452-09-0. Mole weight: 756.9. Purity: 95%+. Catalog: ACM115452090. | |
| Nadifloxacin isomer 3 | An impurity of Nadifloxacin, which is a potent, broad-spectrum, quinolone agent approved for topical use in acne vulgaris and skin infections. Synonyms: 9-fluoro-5-methyl-1-oxo-8-(4-oxopyridin-1(4H)-yl)-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylic acid. Grades: > 95%. Molecular formula: C19H15FN2O4. Mole weight: 354.34. | |
| Nadifloxacin isomer 4 | An impurity of Nadifloxacin, which is a potent, broad-spectrum, quinolone agent approved for topical use in acne vulgaris and skin infections. Synonyms: 8-amino-9-fluoro-5-methyl-1,7-dioxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylic acid. Grades: > 95%. Molecular formula: C15H15FN2O4. Mole weight: 306.3. | |
| (R)-Apomorphine-d3 Hydrochloride | (R)-Apomorphine-d3 Hydrochloride. Group: Biochemicals. Alternative Names: (6aR)-5,6,6a,7-Tetrahydro-6-(methyl-d3)-4H-dibenzo[de,g]quinoline-10,11-diol Hydrochloride; 6a β-Aporphine-10,11-diol-d3 Hydrochloride; (-)-10,11-Dihydroxy-aporphine-d3 Hydrochloride; (-)-Apomorphine-d3 Chloride; (R)-(-)-Apomorphine-d3 Chloride; Apokyn-d3; Apomorphin-d3; Apomorphine-d3; Ixense-d3; l-Apomorphine-d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C17H15D3ClNO2, Molecular Weight: 306.8. US Biological Life Sciences. | Worldwide |
| (R)-Apomorphine-d5 Hydrochloride (Major) | Labelled Apomorphine (A727500). Dopamine (D1 and D2) receptor agonist. Emetic. Antiparkinsonian. Group: Biochemicals. Alternative Names: (R)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-1,2,3,8,9-d5-10,11-diol-d5 Hydrochloride. Grades: Highly Purified. CAS No. 76787-63-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| (R)-Apomorphine Hydrochloride Hemihydrate | Dopamine (D1 and D2) receptor agonist. Emetic. Antiparkinsonian. Group: Biochemicals. Alternative Names: (6aR)-5,6,6a,7-Tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol Hydrochloride Hemihydrate; 6a β-Aporphine-10,11-diol Hydrochloride Hemihydrate; (-)-10,11-Dihydroxy-aporphine Hydrochloride Hemihydrate; Apokyn Hemihydrate; Apomorphin Hemihydrate; Apomorphine Hemihydrate; Ixense Hemihydrate; l-Apomorphine Hemihydrate. Grades: Highly Purified. CAS No. 41372-20-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Tadalafil EP impurity E | Tadalafil EP impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (6R, 12aR, 12bR)-6-(benzo[d][1, 3]dioxol-5-yl)-6a-hydroxy-2-methyl-2, 3, 6a, 7-tetrahydropyrazino[1', 2':1, 5]pyrrolo[3, 4-b]quinoline-1, 4, 12(6H, 12aH, 12bH)-trione. CAS No. 2520114-41-2. Molecular Formula: C22H19N3O6. Mole Weight: 421.40. Catalog: APB2520114412. | |
| Tadalafil Hydroxyquinoline Impurity (EP Impurity G) | One of the impurities of Tadalafil, which is an inhibitor of phosphodiesterase 5 and could be used in the treatmen of erectile dysfunction. Synonyms: Tadalafil EP Impurity G; (12bR)-6-(1, 3-Benzodioxol-5-yl)-12-hydroxy-2-methyl-2, 3, 6, 12b-tetrahydropyrazino[1', 2':1, 5]pyrrolo[3, 4-b]quinoline-1, 4-dione. Grades: > 95%. Molecular formula: C22H17N3O5. Mole weight: 403.39. | |
| Thalicarpine | Thalicarpine is a natural aporphine benzylisoquinoline vinca alkaloid with antineoplastic activity. Thalicarpine binds to and inhibits p-glycoprotein, the multidrug resistance efflux pump. Thalicarpine also induces single-strand breaks in DNA and arrests cancer cells at the G2/M and G1 phase of the cell cycle. Synonyms: Thaliblastine; Taliblastine; Taliblastin; NY-IV-34-1; NSC-68075; NSC 68075; (S)-9-(2-(((S)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)-4,5-dimethoxyphenoxy)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline. CAS No. 5373-42-2. Molecular formula: C41H48N2O8. Mole weight: 696.83. | |
| Zoliflodacin | Zoliflodacin, an oxazolidinone derivative, has been found to be a DNA gyrase inhibitor that could be used as an antibacterial agent. It is still under Phase II trial in Gonorrhea. Uses: Topoisomerase ii inhibitors. Synonyms: UNII-FWL2263R77; AZD-0914; AZD0914; AZD 0914; FWL2263R77; FWL 2263R77; FWL-2263R77; Zoliflodacin; AZD0914; CHEMBL3544978; (2R,4S,4aS)-11-fluoro-2,4-dimethyl-8-((S)-4-methyl-2-oxooxazolidin-3-yl)-1,2,4,4a-tetrahydro-2'H,6H-spiro[isoxazolo[4,5-g][1,4]oxazino[4,3-a]quinoline-5,5'-pyrimidine]-2',4',6'(1. Grades: 98%. CAS No. 1620458-09-4. Molecular formula: C22H22FN5O7. Mole weight: 487.40. | |
| 21s-Argatroban | Heterocyclic Organic Compound. Alternative Names: (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[[(3S)-1,2,3,4-tetrahydro-3-methyl-8-quinolinyl]sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid. CAS No. 121785-72-6. Molecular formula: C23H36N6O5S. Mole weight: 508.63. Purity: 0.96. IUPACName: (2R,4R)-1-[5-(diaminomethylideneamino)-2-[[(3S)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonylamino]pentanoyl]-4-methylpiperidine-2-carboxylic acid. Canonical SMILES: CC1CCN (C (C1)C (=O)O)C (=O)C (CCCN=C (N)N)NS (=O) (=O)C2=CC=CC3=C2NCC (C3)C. Catalog: ACM121785726. | |
| 2,2-Dimethyl-propanoic Acid (6aR)-5,6,6a,7-Tetrahydro-10-hydroxy-6-methyl-4H-dibenzo[de,g]quinolin-11-yl Ester | 2,2-Dimethyl-propanoic Acid (6aR)-5,6,6a,7-Tetrahydro-10-hydroxy-6-methyl-4H-dibenzo[de,g]quinolin-11-yl Ester is an intermediate in the synthesis of (R)-Apomorphine-10-sulfate (A727515). Group: Biochemicals. Grades: Highly Purified. CAS No. 1350191-90-0. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C22H25NO3, Molecular Weight: 351.44. US Biological Life Sciences. | Worldwide |
| 2-[6-(2,2-Dicyanoethenyl)-2,2,4,7-tetramethyl-3,4-dihydroquinolin-1-yl]ethyl N-phenylcarbamate | Heterocyclic Organic Compound. Alternative Names: 2-[6-(2,2-dicyanovinyl)-2,2,4,7-tetramethyl-3,4-dihydroquinolin-1(2h)-yl]ethyl phenylcarbamate, 1849-80-5, EINECS 242-067-0, AC1Q4PXZ, AC1L3C22, CTK8D6545, AR-1D6996, 12223-99-3, 2-(6-(2,2-Dicyanovinyl)-1,2,3,4-tetrahydro-2,2,4,7-tetramethylquinolin-1-yl)ethyl carbanilate, 2-[6-(2,2-dicyanoethenyl)-2,2,4,7-tetramethyl-3,4-dihydroquinolin-1-yl]ethyl N-phenylcarbamate, 58253-11-5, Propanedinitrile, ( (1, 2, 3, 4-tetrahydro-2, 2, 4, 7-tetramethyl-1- (2- ( ( (phenylamino)carbonyl)oxy)ethyl)-6-quinolinyl)methylene)-, Propanedinitrile, 2- ( (1, 2, 3, 4-tetrahydro-2, 2, 4, 7-tetramethyl-1- (2- ( ( (phenylamino)carbonyl)oxy)ethyl)-6-quinolinyl)methylene)-. CAS No. 12223-99-3. Molecular formula: C26H28N4O2. Mole weight: 428.526 g/mol. Purity: 0.96. IUPACName: 2-[6-(2,2-dicyanoethenyl)-2,2,4,7-tetramethyl-3,4-dihydroquinolin-1-yl]ethyl N-phenylcarbamate. Canonical SMILES: CC1CC (N (C2=C1C=C (C (=C2)C)C=C (C#N)C#N)CCOC (=O)NC3=CC=CC=C3) (C)C. ECNumber: 602-362-0. Catalog: ACM12223993. | |
| (2-Methyl-1,2,3,4-tetrahydro-quinolin-4-yl)-phenyl-amine | Heterocyclic Organic Compound. Alternative Names: AKOS BBS-00005674;(2-METHYL-1,2,3,4-TETRAHYDRO-QUINOLIN-4-YL)-PHENYL-AMINE;ASISCHEM N44996;N-(2-METHYL-1,2,3,4-TETRAHYDRO-4-QUINOLINYL)-N-PHENYLAMINE. CAS No. 1026-05-7. Molecular formula: C16H18N2. Mole weight: 238.33. Catalog: ACM1026057. | |
| (2S,4S)-Argatroban | Synthetic thrombin inhibitor. Antithrombotic. Group: Biochemicals. Alternative Names: (2S, 4S) -1-[ (2S) -5-[ (Aminoiminomethyl) amino]-1-oxo-2-[[ (1, 2, 3, 4-tetrahydro-3-methyl-8-quinolinyl) sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid. Grades: Highly Purified. CAS No. 189264-03-7. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| (2S,4S)-Argatroban | Synthetic thrombin inhibitor. Synonyms: (2S,4S)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid. Grades: > 95%. CAS No. 189264-03-7. Molecular formula: C23H36N6O5S. Mole weight: 508.64. | |
| 3-Quinolinamine,5,6,7,8-tetrahydro-2-methyl- | Heterocyclic Organic Compound. CAS No. 113738-00-4. Catalog: ACM113738004. | |
| (3R, 4R) -Rel-tetrahydro-N-hydroxy-4-[[4-[ (2-methyl-4-quinolinyl) methoxy]benzoyl]amino]-2H-pyran-3-carboxamide | Heterocyclic Organic Compound. CAS No. 1006891-27-5. Molecular formula: C24H25N3O5. Mole weight: 435.4724;g/mol. Purity: 0.96. IUPACName: (3R,4R)-N-hydroxy-4-[[4-[(2-methylquinolin-4-yl)methoxy]benzoyl]amino]oxane-3-carboxamide. Canonical SMILES: CC1=NC2=CC=CC=C2C (=C1)COC3=CC=C (C=C3)C (=O)NC4CCOCC4C (=O)NO. Catalog: ACM1006891275. | |
| Apomorphine Sulfate-[d5] | Apomorphine Sulfate-[d5] is an isotope compound of Apomorphine Sulfate, a derivative of Apomorphine. Synonyms: (R)-11-hydroxy-1,2,3,6,8,9-D5-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-10-yl hydrogen sulfate; [(9R)-3-hydroxy-10-methyl(5, 6, 14, 15, 16-D5)-10-azatetracyclo[7.7.1.0, 7.0, 7]heptadeca-1(17), 2, 4, 6, 13, 15-hexaen-4-yl]oxidanesulfonic acid. Grades: > 98%. Molecular formula: C17H17NO5S. Mole weight: 352.42. | |
| Argatroban | Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor. Uses: Antithrombins; platelet aggregation inhibitors. Synonyms: (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8-quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid. Grades: >98%. CAS No. 74863-84-6. Molecular formula: C23H36N6O5S. Mole weight: 508.63. | |
| Argatroban ( (2R, 4R) -1-[ (2S) -5-[ (Aminoiminomethyl) amino]-1-oxo-2-[[ (1, 2, 3, 4-tetrahydro-3-methyl-8-quinolinyl) sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid, Argipidine, MQPA) | Synthetic thrombin inhibitor. Group: Biochemicals. Alternative Names: (2R, 4R) -1-[ (2S) -5-[ (Aminoiminomethyl) amino]-1-oxo-2-[[ (1, 2, 3, 4-tetrahydro-3-methyl-8-quinolinyl) sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid; Argipidine; MQPA. Grades: Highly Purified. CAS No. 74863-84-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Argatroban-d3 | Labeled synthetic thrombin inhibitor. Antithrombotic. Group: Biochemicals. Alternative Names: (2R, 4R) -1-[ (2S) -5-[ (Aminoiminomethyl) amino]-1-oxo-2-[[ (1, 2, 3, 4-tetrahydro-3- (methyl-d3) -8-quinolinyl) sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid; Argipidine-d3; MQPA-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Argatroban Related Impurity 2 | A metabolite of Argatroban. Synonyms: (2R,4R)-1-[(2S)-5-[(Aminoiminomethyl)amino]-1-oxo-2-[[[(3R)-1,2,3,4-tetrahydro-3-methyl-8-quinolinyl]sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic Acid. Grades: > 95%. CAS No. 189264-02-6. Molecular formula: C23H36N6O5S. Mole weight: 508.64. | |
| AS 2034178 | AS 2034178 has been found to be a FFA1/GPR40 agonist and could probably be used against diabetes. Synonyms: AS 2034178; AS2034178; AS-2034178; 2-Fluoro-4- [ [ [1, 2, 3, 4-Tetrahydro-1- (2-phenoxyethyl) -5-quinolinyl] methyl] amino] benzenepropanoic acid. Grades: ≥98% by HPLC. CAS No. 1030846-42-4. Molecular formula: C27H29FN2O3. Mole weight: 448.53. | |
| AZD0156 | AZD0156 is an orally active, potent and selective ataxia telangiectasia mutated (ATM) kinase inhibitor, used for cancer treatment. AZD0156 prevents DNA damage checkpoint activation, and disrupts DNA damage repair, inducing tumor cell apoptosis, and leading to cell death in ATM-overexpressing tumor cells. Uses: Protein kinase inhibitors. Synonyms: 8-[6-[3-(dimethylamino)propoxy]-3-pyridyl]-3-methyl-1-tetrahydropyran-4-yl-imidazo[4,5-c]quinolin-2-one; AZD0156; AZD-0156; AZD 0156. CAS No. 1821428-35-6. Molecular formula: C26H31N5O3. Mole weight: 461.56. | |
| Baxdrostat | Baxdrostat is an aldosterone synthase inhibitor. Synonyms: N-[(8R)-4-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide; (R)-N-(4-(1-methyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide; N-[(8R)-4-(1-Methyl-2-oxo-1,2,3,4-tetrahydro-6-quinolinyl)-5,6,7,8-tetrahydro-8-isoquinolinyl]propanamide; Propanamide, N-[(8R)-5,6,7,8-tetrahydro-4-(1,2,3,4-tetrahydro-1-methyl-2-oxo-6-quinolinyl)-8-isoquinolinyl]-. CAS No. 1428652-17-8. Molecular formula: C22H25N3O2. Mole weight: 363.45. | |
| BAY 56-3722 | BAY 56-3722 is a water-soluble camptothecin derivative conjugated to a carbohydrate moiety exhibiting antineoplastic activity. BAY 56-3722 stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. The peptide carbohydrate moiety of this agent stabilizes the lactone form of camptothecin in blood. Synonyms: BAY-563722; BAY56 3722; BAY 38-3441; BAY 38 344; (S)-4-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl ((4-(((2R,3S,4R,5R,6S)-3,5-dihydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)phenyl)carbamothioyl)-L-histidyl-L-valinate. CAS No. 215604-75-4. Molecular formula: C45H50ClN7O11S. Mole weight: 895.98. | |
| BAY 56-3722 hydrochloride | BAY 56-3722, a water-soluble camptothecin derivative, is a DNA-Intercalating drug that stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. Synonyms: BAY 56-3722; BAY56-3722; BAY-56-3722; N-[4- (6-Deoxy-3-O-methyl-beta-L-galactopyranosyloxy) phenylaminothiocarbonyl]-L-histidyl-L-valine 4(S)-ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-4-yl ester hydrochloride; N-[4-(3-O-Methyl-beta-L-fucopyranosyloxy)p; Afeletecan hydrochloride; BAY 38-3441; L-Valine, N- ( ( (4- ( (6-deoxy-3-O-methyl-beta-L-galactopyranosyl) oxy) phenyl) amino) thioxomethyl) -L-histidyl-, (4S)-4-ethyl-3,4,12,14-tetrahydro-3,14-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-4-yl ester, hydrochloride (1:1); 215604-75-4 (BAY 56-3722 free base); 215604-74-3 (BAY 56-3722 HCl salt; 215604-66-3 (diastereomeric mixture). Grades: >98%. CAS No. 215604-74-3. Molecular formula: C45H49N7O11S.HCl. Mole weight: 932.447. | |
| (-)-Blebbistatin | (-)-Blebbistatin. Group: Biochemicals. Alternative Names: 1,2,3,3a-tetrahydro-3aS-hydroxy-6-methyl-1-phenyl-4H-Pyrrolo[2,3-b]quinolin-4-one, (S)-(-)-Blebbistatin. Grades: Highly Purified. CAS No. 856925-71-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C18 H16 N2O2, Molecular Weight: 292.3. US Biological Life Sciences. | Worldwide |
| (+)-Blebbistatin | (+)-Blebbistatin is the inactive enantiomer of Blebbistatin, an inhibitor of myosin II ATPase. (+)-Blebbistatin can be used as a negative control of the active enatiomer (-)-Blebbistatin. Synonyms: (R)-(+)-Blebbistatin; (3aR)-(+)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one. Grades: ≥99% by HPLC. CAS No. 1177356-70-5. Molecular formula: C18H16N2O2. Mole weight: 292.34. | |
| (±)-Blebbistatin | (±)-Blebbistatin is a selective inhibitor of myosin II ATPase. It reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells; inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Synonyms: Blebbistatin; (±)-1,2,3,3a-Tetrahydro-3a-hydroxy-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one. Grades: ≥98% by HPLC. CAS No. 674289-55-5. Molecular formula: C18H16N2O2. Mole weight: 292.34. | |
| Boc-Ala[3-(1-THQ)]-OH | Synonyms: Boc-Ala[3-(1,2,3,4-tetrahydroquinolin-1-yl)]-OH; N-α-(t-Butoxycarbonyl)-3-(1,2,3,4-tetrahydroquinolin-1-yl)-L-alanine; (2S)-3-(3,4-Dihydro-2H-quinolin-1-yl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid. Molecular formula: C17H24N2O4. Mole weight: 320.38. | |
| boldine EP Impurity D | boldine EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-1,2,10-trimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-9-ol. CAS No. 3019-51-0. Molecular Formula: C20H23NO4. Mole Weight: 341.40. Catalog: APB3019510. | |
| Cefquinome sulfate | Cefquinome is a fourth-generation cephalosporin with pharmacological and antibacterial properties valuable in the treatment of coliform mastitis and other infections. Cefquinome sulfate is used in the treatment of infections caused by pathogens such as S. aureus, E. coli, Streptococcus, P. multocida and A. pleuropneumoniae. It can be used to treat respiratory infections in pigs, cattle and sheep caused by sensitive bacteria, dairy cow mastitis and sow agalactia syndrome, and can prevent piglet diarrhea, Haemophilus parasuis and streptococcus disease. Synonyms: Quinolinium, 1-[[(6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-5,6,7,8-tetrahydro-, sulfate (1:1); Quinolinium, 1-[[ (6R, 7R)-7-[[ (2Z)- (2-amino-4-thiazolyl) (methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4. 2. 0]oct-2-en-3-yl]methyl]-5, 6, 7, 8-tetrahydro-, sulfate (1:1); Quinolinium, 1-[[7-[[ (2-amino-4-thiazolyl) (methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4. 2. 0]oct-2-en-3-yl]methyl]-5, 6, 7, 8-tetrahydro-, [6R-[6α,7β(Z)]]-, sulfate (1:1); Cefquinome sulphate; HR 111V sulfate. Grades: ≥98%. CAS No. 118443-89-3. Molecular formula: C23H27N6O9S3. Mole weight: 626.68. | |
| Cefquinome Sulfate | An antibacterial used in veterinary medicine. Used in the treatment of infections caused by pathogens such as S. aureus, E. coli, Streptococcus, P. multocida and A. pleuropneumoniae. Also used to treat mastitis in dairy cows. Group: Biochemicals. Alternative Names: 1-[[ (6R, 7R) -7-[[ (2Z) -2- (2-Amino-4-thiazolyl) -2- (methoxyimino) acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4. 2. 0]oct-2-en-3-yl]methyl]-5, 6, 7, 8-tetrahydro-quinolinium Sulfate; Cefquinome Sulphate; HR 111V Sulfate; [6R-[6α,7 β (Z) ]]-1-[[7-[[ (2-amino-4-thiazolyl) (methoxyimino) acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4. 2. 0]oct-2-en-3-yl]methyl]-5, 6, 7, 8-tetrahydro-quinolinium Sulfate. Grades: Highly Purified. CAS No. 118443-89-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| dCBP-1 | dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP based on Cereblon ligand. dCBP-1 is exceptionally potent at killing multiple myeloma cells and can abolish the enhancer that drives MYC oncogene expression. As an efficient degrader of this unique class of acetyltransferases, dCBP-1 is a useful tool alongside domain inhibitors for dissecting the mechanism by which these factors coordinate enhancer activity in normal and diseased cells. Group: Others. Alternative Names: dCBP-1; dCBP 1; dCBP1. CAS No. 2484739-25-3. Molecular formula: C51H63F2N11O10. Mole weight: 1028.13. Appearance: Solid powder. Purity: >98%. IUPACName: 5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1Hpyrazol-4-yl)-1(2H)-quinolinyl]-1-[1-[15-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]-1-oxo-4,7,10,13-tetraoxapentadec-1-yl]-4-piperidinyl]-1,4,6,7-tetrahydro-N-methyl-. Canonical SMILES: O=C (N1CCC (N (C2CCN (C (CCOCCOCCOCCOCCNC3=CC4=C (C (N (C (CC5) C (NC5=O) =O) C4=O) =O) C=C3) =O) CC2) N=C6N7CCCC8=C7C=C (C (F) F) C (C9=CN (C) N=C9) =C8) =C6C1) NC. Catalog: ACM2484739253. | |
| Deoxy blebbistatin | Deoxy blebbistatin. Group: Biochemicals. Alternative Names: 1,2,3,9-Tetrahydro-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one. Grades: Highly Purified. CAS No. 856925-72-9. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C18H16N2O. US Biological Life Sciences. | Worldwide |
| GNE-781 | GNE-781 is a Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP). GNE-781 showed TR-FRET IC50=0.94 nM, BRET IC50=6.2 nM, BRD4(1) IC50=5,100 nΜ) that maintained good in vivo PK properties in multiple species. GNE-781 displays anti-tumor activity in an AML tumor model and was also shown to decrease Foxp3 transcript levels in a dose dependent manner. Group: Inhibitors. Alternative Names: GNE-781; GNE 781; GNE781. CAS No. 1936422-33-1. Molecular formula: C27H33F2N7O2. Mole weight: 525.6. Appearance: Solid powder. Purity: >98%. IUPACName: 3-[7-(difluoromethyl)-6-(1-methylpyrazol-4-yl)-3,4-dihydro-2H-quinolin-1-yl]-N-methyl-1-tetrahydropyran-4-yl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-5-carboxamide. Canonical SMILES: O=C (N1CCC (N (C2CCOCC2)N=C3N4CCCC5=C4C=C (C (F)F)C (C6=CN (C)N=C6)=C5)=C3C1)NC. Catalog: ACM1936422331. | |
| Irinotecan EP Impurity H | An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Synonyms: (S)-11-Ethyl-4-hydroxy-4-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate; 4-methyl irinotecan analogue. Molecular formula: C32H36N4O6. Mole weight: 572.65. | |
| Irinotecan Related Compound C | An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Synonyms: 11-Ethyl-4-hydroxy-4-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl (1,4'-bipiperidine)-1'-carboxylate hydrochloride; USP Irinotecan Related Compound C. Molecular formula: C32H37ClN4O6. Mole weight: 609.11. | |
| Naphthoquine phosphate | Naphthoquine phosphate and artemisinine are two antimalarials developed in China. Both drugs have proven to be efficacious and well tolerated as monotherapy as well as in combination in patients suffering from malaria. The Co-naphthoquine, a novel antimalarial combination, is an oral fixed combination tablet of the naphthoquine phosphate and artemisinine. Artemisinin is characterised by a rapid onset of schizonticidal action and a short half-life. Parasite clearance is, however, often incomplete when it is employed as a single agent unless high dosages are used over several days, but such a regimen may reduce patient compliance and increase the danger of toxicity. Naphthoquine phosphate, by contrast, has a slower onset of action and a longer half-life, associated with a low recrudescence rate. Synonyms: 1-Naphthalenol, 4-[(7-chloro-4-quinolinyl)amino]-2-[[(1,1-dimethylethyl)amino]methyl]-5,6,7,8-tetrahydro-, phosphate (1:2) (salt); 2-((tert-butylamino)methyl)-4-((7-chloroquinolin-4-yl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol bis(phosphate); Naphthoquine diphosphate. Grades: >98%. CAS No. 173531-58-3. Molecular formula: C24H34ClN3O9P2. Mole weight: 605.94. | |
| PF 3644022 | PF 3644022 is a potent freely reversible ATP-competitive compound that inhibits MK2 activity (IC50 = 5.2 nM; Ki = 3 nM) with good selectivity when profiled against 200 human kinases. PF 3644022 inhibits tumor necrosis factor α (TNFα) production in U937 monocytic cells and peripheral blood mononuclear cells (PBMCs) (IC50 = 160 nM). Synonyms: (10R)-9,10,11,12-Tetrahydro-10-methyl-3-(6-methyl-3-pyridinyl)-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-onel; PF-3644022; PF 3644022; PF3644022. Grades: ≥98% by HPLC. CAS No. 1276121-88-0. Molecular formula: C21H18N4OS. Mole weight: 374.46. | |
| PF-3644022 | PF-3644022 is a potent freely reversible ATP-competitive compound that inhibits MK2 activity (Ki = 3 nM) with good selectivity when profiled against 200 human kinases. PF-3644022 is a benzothiophene inhibitor of mitogen-activated protein kinase-activated protein kinase 2 inhibits tumor necrosis factor α production and has oral anti-inflammatory efficacy in acute and chronic models of inflammation. Group: Biochemicals. Alternative Names: (10R)-9, 10, 11, 12-Tetrahydro-10-methyl-3-(6-methyl-3-pyridinyl)-8H-[1, 4]diazepino[5', 6':4, 5]thieno[3, 2-f]quinolin-8-one. Grades: Highly Purified. CAS No. 1276121-88-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (R-(-)-Apocodeine hydrochloride | (R-(-)-Apocodeine hydrochloride. Group: Biochemicals. Alternative Names: (6aR)-5,6,6a,7-Tetrahydro-10-methoxy-6-methyl-4H-dibenzo[de,g]quinolin-11-ol hydrochloride; 10-Methoxy-6a-b-aporphin-11-ol monohydrochloride; NSC 305238. Grades: Highly Purified. CAS No. 6377-14-6. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C18H20ClNO2. US Biological Life Sciences. | Worldwide |
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