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(2R)-2-Amino-4-methyl-1-[(2R)-2-methyloxiran-2-yl]pentan-1-one Trifluoroacetate Salt
(2R)-2-Amino-4-methyl-1-(2-methyloxiran-2-yl)pentan-1-one Trifluoroacetate Salt s an impurity of carfilzomib (C183460). Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C11H18F3NO4, Molecular Weight: 285.26. US Biological Life Sciences.
(2S)-2-Amino-4-methyl-1-[(2R)-2-methyloxiranyl]-1-pentanone Trifluoroacetate is an intermediate of Carfilzomib (C183460) which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Grades: Highly Purified. CAS No. 247068-85-5. Pack Sizes: 1mg, 10mg. Molecular Formula: C11H18F3NO4, Molecular Weight: 285.26. US Biological Life Sciences.
Bortezomib intermediate. A boronic acid dipeptide derivative as proteasome inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 179324-87-9. Pack Sizes: 25mg. US Biological Life Sciences.
D-Alanine 7-amido-4-methylcoumarin trifluoroacetate is a biochemical compound used in the biomedical industry serving as a substrate for enzyme assays, specifically for the detection of various enzymes involved in drug metabolism, such as dehydrogenases and decarboxylases. Synonyms: H-D-Ala-AMC TFA; Propanamide, 2-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, (2R)-, 2,2,2-trifluoroacetate (1:1); Propanamide, 2-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, (2R)-, mono(trifluoroacetate); Propanamide, 2-amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, (R)-, mono(trifluoroacetate). Grade: ≥95%. CAS No. 201847-52-1. Molecular formula: C15H15F3N2O5. Mole weight: 360.29.
L-Phenylalanine 7-amido-4-methylcoumarin trifluoroacetate 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Worldwide
L-Phenylalanine 7-amido-4-methylcoumarin trifluoroacetate salt
L-Phenylalanine 7-Amido-4-methylcoumarin, Trifluoroacetate Salt is a fluorogenic substrate for phenylalanine peptidase yielding a blue fluorescent solution from cleavage. L-Phenylalanine 7-Amido-4-methylcoumarin, Trifluoroacetate Salt can be used as reactant/reagent for activation of lymphocyte progranzyme by dipeptidyl peptidase I. Synonyms: (S)-2-Amino-N-(4-Methyl-2-Oxo-2H-Chromen-7-Yl)-3-Phenylpropanamide 2,2,2-Trifluoroacetate; L-Phenylalanine-AMC TFA salt. Grade: ≥ 98% (HPLC). CAS No. 108321-84-2. Molecular formula: C21H19F3N2O5. Mole weight: 436.38.
An intermediate of Carfilzomib, which is a second-generation proteasome inhibitor for the treatment of relapsed and refractory multiple myeloma. Synonyms: 1-Pentanone, 2-amino-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-, (2S)-, 2,2,2-trifluoroacetate (1:1); 1-Pentanone, 2-amino-4-methyl-1-[(2R)-2-methyloxiranyl]-, (2S)-, trifluoroacetate; (2R)-2-[(2S)-2-Amino-4-methylpentanoyl]-2-methyloxirane trifluoroacetate; (2S)-2-Amino-4-methyl-1-[(2R)-2-methyloxiranyl]-1-pentanone Trifluoroacetate; (2S)-2-Amino-4-methyl-1-[(2R)-2-methyl-2-oxiranyl]-1-pentanone 2,2,2-Trifluoroacetate. Grade: ≥95%. CAS No. 247068-85-5. Molecular formula: C9H17NO2.C2HF3O2. Mole weight: 285.26.
4-10-Neuromedin b(swine spinal cord),N-(3-carboxy-1-oxopropyl)-6-(N-methyl-L-phenylalanine)-7-de-L-valine-(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: [SUCCINYL-ASP6,ME-PHE8] SUBSTANCE P;SUCCINYL-(ASP6,N-ME-PHE8)-SUBSTANCE P (6-11);[SUCCINYL-ASP6 N-ME-PHE8]-SUBSTANCE P (6-11) (SENKTIDE);[SUCCINYL-ASP6,N-ME-PHE8]-SUBSTANCE P, FRAGMENT 6-11;SUCCINYL-ASP-PHE-ME-PHE-GLY-LEU-MET-NH2;SUCCINYL-ASP-PHE-(N-ME)P. Product Category: Heterocyclic Organic Compound. Appearance: White powder. CAS No. 106128-89-6. Molecular formula: C40H55N7O11S. Mole weight: 841.97. Purity: 0.96. IUPACName: (3S)-4-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]-methylamino]-1-oxo-3-phenylpropan-2-yl]amino]-3-[(4-hydroxy-4-oxobutanoyl)amino]-4-o. Density: 1.29 g/cm³. Product ID: ACM106128896. Alfa Chemistry ISO 9001:2015 Certified. Categories: Senktide trifluoroacetate salt.
4-(Maleimidomethyl)cyclohexane-1-carboxyl-hydrazide,trifluoroacetic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SMCC-Hydrazide, MMCCH; 4-[(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexanecarboxylic Acid Hydrazide, 2,2,2-Trifluoroacetate. Product Category: Heterocyclic Organic Compound. Appearance: White to Off-White. CAS No. 359436-59-2. Molecular formula: C12H17N3O3?CF3CO2H. Mole weight: 365.31. Purity: 0.96. IUPACName: 4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexane-1-carbohydrazide;2,2,2-trifluoroacetic acid. Canonical SMILES: C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)NN.C(=O)(C(F)(F)F)O. Product ID: ACM359436592. Alfa Chemistry ISO 9001:2015 Certified.
(6R-trans)-7-[[[3-(2-Aminoethoxy)phenyl]acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid TFA salt
An impurity of Cefazolin, an antibiotic used for the treatment of bacterial infections. Synonyms: 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[3-(2-aminoethoxy)phenyl]acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-, (6R-trans)-, mono(trifluoroacetate); Acetic acid, trifluoro-, compd. with (6R-trans)-7-[[[3-(2-aminoethoxy)phenyl]acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (1:1); Trifluoroacetic acid compd. with (6R-trans)-7-[[[3-(2-aminoethoxy)phenyl]acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Grade: >95%. CAS No. 42059-11-0. Molecular formula: C23H24F3N5O7S3. Mole weight: 635.66.
Abaloparatide TFA
Abaloparatide TFA is an analog of parathyroid hormone-related protein (PTHrP) used for the treatment of osteoporosis. Synonyms: H-Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Glu-Leu-Leu-Glu-Lys-Leu-Leu-Aib-Lys-Leu-His-Thr-Ala-NH2.TFA; L-alanyl-L-valyl-L-seryl-L-alpha-glutamyl-L-histidyl-L-glutaminyl-L-leucyl-L-leucyl-L-histidyl-L-alpha-aspartyl-L-lysyl-glycyl-L-lysyl-L-seryl-L-isoleucyl-L-glutaminyl-L-alpha-aspartyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-alpha-glutamyl-L-leucyl-L-leucyl-L-alpha-glutamyl-L-lysyl-L-leucyl-L-leucyl-alpha-methyl-alanyl-L-lysyl-L-leucyl-L-histidyl-L-threonyl-L-alaninamide trifluoroacetic acid; BIM 44058 trifluoroacetate; Eladynos trifluoroacetate. Grade: ≥95%. Molecular formula: C176H301N56F3O51. Mole weight: 4074.61.
Abz-LFK(Dnp)-OH trifluoroacetate salt
Abz-LFK(Dnp)-OH trifluoroacetate salt is an angiotensin-converting enzyme (ACE) fluorescent peptide substrate that binds specifically to the C domain of ACE. It has been used to investigate the development of novel antibacterial calixarene derivatives, as well as the efficacy and toxicity of antimicrobial peptide M33 as a possible antimicrobial agent for lung infections and sepsis. Synonyms: O-Aminobenzoic acid-Leu-Phe-Lys(DNP)-OH trifluoroacetate salt; Abz-Leu-Phe-Lys-DNP trifluoroacetate salt; (2-aminobenzoyl)-L-leucyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine trifluoroacetic acid; N-(2-Aminobenzoyl)-L-leucyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-L-lysine trifluoroacetate (1:1); L-Lysine, N-(2-aminobenzoyl)-L-leucyl-L-phenylalanyl-N6-(2,4-dinitrophenyl)-, compd. with 2,2,2-trifluoroacetic acid (1:1); (2S)-2-[[(2S)-2-([(2S)-2-[(2-Aminobenzoyl)amino]-4-methylpentanoyl]amino)-3-phenylpropanoyl]amino]-6-(2,4-dinitroanilino)hexanoic acid trifluoroacetate. Grade: ≥97% by HPLC. CAS No. 1217437-31-4. Molecular formula: C34H41N7O9.C2HF3O2. Mole weight: 805.76.
BIBO 3304 trifluoroacetate
BIBO 3304 trifluoroacetate is a potent NPY Y1 receptor antagonist (IC50 = 0.38 and 0.72 nM at human and rat receptors, respectively) displaying > 2600-fold selectivity over Y2, Y4 and Y5 receptors. BIBO 3304 inhibits NPY- and fasting-induced feeding in vivo following central administration. It may be a treatment of bone mass. Synonyms: BIIE-0246; BIIE 0246; BIIE-0246; CHEMBL540989; GTPL1547; CTK8E9439; BIIE0246; N-[(1R)-1-[[[[4-[[(Aminocarbonyl)amino]methyl]phenyl]methyl]amino]carbonyl]-4-[(aminoiminomethyl)amino]butyl]-α-phenyl-benzeneacetamide ditrifluoroacetate. Grade: ≥98% by HPLC. CAS No. 191868-14-1. Molecular formula: C29H35N7O3.2CF3CO2H. Mole weight: 757.69.
BIBP 3226 TFA
BIBP 3226 trifluoroacetate is a mixed non-peptide neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist (Ki = 1.1, 79, 108, > 1000, > 1000 and >1000 for rNPY Y1, hNPFF2, rNPFF, rNPY Y2, rNPY Y4 and rNPY Y5, respectively). BIBP 3226 exhibits an anxiogenic-like effect in rats following i.c.v. administration. Synonyms: BIBP 3226 trifluoroacetate; BIBP3226 trifluoroacetate; BIBP-3226 trifluoroacetate; N-[(1R)]-4-[(Aminoiminomethyl)amino-1-[[[(4-hydroxyphenyl)methyl]amino]carbonyl]butyl-α-phenylbenzeneacetamide trifluoroacetate; N5-(Diaminomethylene)-N2-(2,2-diphenylacetyl)-N-(4-hydroxybenzyl)-D-ornithinamide trifluoroacetate; Diphenylacetyl-D-Arg-4-hydroxybenzylamide trifluoroacetate. Grade: ≥98% by HPLC. CAS No. 1068148-47-9. Molecular formula: C27H31N5O3.C2HF3O2. Mole weight: 587.59.
BNM-III-170
BNM-III-170 can inhibit HIV-1 virus entry into target cells. Synonyms: N1-(4-Chloro-3-fluorophenyl)-N2-((1R,2R)-2-(guanidinomethyl)-5-((methylamino)methyl)-2,3-dihydro-1H-inden-1-yl)oxalamide bis(2,2,2-trifluoroacetate). Grade: ≥95%. CAS No. 1859189-55-1. Molecular formula: C25H26ClF7N6O6. Mole weight: 674.95.
Boc-LRR-AMC (trifluoroacetate salt)
Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core. Synonyms: Boc-Leu-Arg-Arg-AMC.TFA; N-[(1,1-dimethylethoxy)carbonyl]-L-leucyl-L-arginyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide, trifluoroacetate salt. Grade: 95%. Molecular formula: C35H53F3N10O9. Mole weight: 814.87.
BRD 4354 ditrifluoroacetate
BRD 4354 ditrifluoroacetate is a moderately potent HDAC5 and HDAC9 inhibitor with IC50s of 0.85 and 1.88 μM, respectively. Synonyms: 8-Quinolinol, 5-chloro-7-[(4-ethyl-1-piperazinyl)-3-pyridinylmethyl]-, 2,2,2-trifluoroacetate (1:2); 5-Chloro-7-[(4-ethyl-1-piperazinyl)(3-pyridinyl)methyl]-8-quinolinol trifluoroacetate (1:2). CAS No. 2444837-63-0. Molecular formula: C25H25ClF6N4O5. Mole weight: 610.93.
Ceftolozane TFA salt
Ceftolozane TFA salt is the salt of Ceftolozane, which is the fifth-generation cephalosporin antibiotic. It is a semi-synthetic β-lactam antibiotic used to treat Gram-negative or Gram-positive bacterial infections that have developed resistance to conventional antibiotics. Synonyms: 5-Amino-2-(((6R,7R)-7-((Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(((2-carboxypropan-2-yl)oxy)imino)acetamido)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)-4-(3-(2-aminoethyl)ureido)-1-methyl-1H-pyrazol-2-ium 2,2,2-trifluoroacetate; 1H-Pyrazolium, 5-amino-4-[[[(2-aminoethyl)amino]carbonyl]amino]-2-[[(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, 2,2,2-trifluoroacetate (1:1); 5-Amino-4-{[(2-aminoethyl)carbamoyl]amino}-2-{[(6R,7R)-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxy-2-propanyl)oxy]imino}acetyl]amino}-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-methyl-1H-pyrazol-2-ium trifluoroacetate; CXA-101 TFA salt; Ceftolozane trifluoroacetate. Grade: ≥95%. CAS No. 1628046-32-1. Molecular formula: C23H30N12O8S2.C2HF3O2. Mole weight: 780.71.
CFLZ-171 formic acid salt
CFLZ-171 is an important intermediate to synthesis carfilzomib which is an anti-cancer drug acting as a selective proteasome inhibitor. Synonyms: CFLZ-171 formic acid salt; CFLZ 171 formic acid salt; CFLZ171 formic acid salt; carfilzomib intermediate molecule weight 171. 1Pentanone 2amino4methyl1(2R)2methyl2oxiranyl (2S) 222trifluoroacetate (1:1); 1Pentanone 2amino4methyl1(2R)2methyloxiranyl (2S) trifluoroacetate (9CI); S)-2-amino-4-methyl-1-((R)-2-methyloxiran-2-yl)pentan-1-one 2,2,2-trifluoroacetate. Grade: 98%. CAS No. 1140908-93-5. Molecular formula: C9H17NO2.CH2O2. Mole weight: 217.27.
D-Alaninamide,d-phenylalanyl-L-phenylalanyl-L-tyrosyl-D-tryptophyl-L-Lysyl-L-valyl-l-phenylalanyl-3-(2-naphthalenyl)-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BIM 23056;D-PHE-PHE-TYR-D-TRP-LYS-VAL-PHE-D-NAL-NH2;D-Phe-Phe-Tyr-D-Trp-Lys-VaL-Phe-D-Nal-NH2 trifluoroacetate salt;M.W. 1232.49 C71H81N11O9. Product Category: Heterocyclic Organic Compound. Appearance: White lyophilised solid. CAS No. 150155-61-6. Molecular formula: C71H81N11O9. Mole weight: 1232.49. Purity: 0.96. IUPACName: (2S)-6-amino-N-[(2S)-1-[[(2S)-1-[[(2R)-1-amino-3-naphthalen-2-yl-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-(4-hydroxyp. Canonical SMILES: CC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC2=CC3=CC=CC=C3C=C2)C(=O)N)NC(=O)C(CCCCN)NC(=O)C(CC4=CNC5=CC=CC=C54)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(CC7=CC=CC=C7)NC(=O)C(CC8=CC=CC=C8)N. Product ID: ACM150155616. Alfa Chemistry ISO 9001:2015 Certified.
Desmethoxy gatifloxacin trifluoroacetate
Desmethoxy gatifloxacin trifluoroacetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-Cyclopropyl-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Trifluoroacetate; AM 1121; CNV 8912; CNV 97100; ITV 8912. Product Category: Heterocyclic Organic Compound. Appearance: Off-White to Pale Yellow Solid. CAS No. 93107-32-5. Molecular formula: C20H21F4N3O5. Mole weight: 459.39. Purity: 0.96. IUPACName: 1-cyclopropyl-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid. Canonical SMILES: CC1CN(CCN1)C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4CC4)F. Density: 1.399g/cm³. Product ID: ACM93107325. Alfa Chemistry ISO 9001:2015 Certified.
DPC-AJ1951 is a potent 14 amino acid peptide agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR). It induces cAMP production in SAOS-2 and UMR106 cells that endogenously express human and rat PPR, respectively (EC50s = 2.2 and 1.1 nM, respectively). Synonyms: 2-methylalanyl-L-valyl-2-methylalanyl-L-α-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-norleucyl-L-histidyl-L-glutaminyl-L-arginyl-L-alanyl-L-lysyl-L-tyrosinamide, trifluoroacetate salt. Grade: ≥95%. CAS No. 943519-33-3. Molecular formula: C76H127N23O19·xCF3COOH. Mole weight: 1667.
EGFR-IN-1 TFA
EGFR-IN-1 TFA is an orally active and irreversible mutant selective EGFR inhibitor of L858R/T790M that effectively inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. It shows strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. It has antitumor activity. Synonyms: N-{3-[2-({4-[2-(Dimethylamino)ethoxy]-2-methoxyphenyl}amino)-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl]phenyl}acrylamide trifluoroacetate (1:1); Acetic acid, 2,2,2-trifluoro-, compd. with N-[3-[2-[[4-[2-(dimethylamino)ethoxy]-2-methoxyphenyl]amino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl]phenyl]-2-propenamide (1:1). Grade: ≥99%. Molecular formula: C30H31F3N6O6. Mole weight: 628.60.
EPZ011989 trifluoroacetate
EPZ011989 trifluoroacetate is the trifluoroacetate salt form of EPZ011989. EPZ011989 is a potent and orally bioavailable inhibitor that specifically targets the protein methyltransferase Enhancer of Zeste Homolog 2 (EZH2), with significant tumor growth in. Synonyms: EPZ011989 TFA salt; EPZ011989 TFA; EPZ 011989 TFA; EPZ-011989 TFA; N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-3-[ethyl-[4-[2-methoxyethyl(methyl)amino]cyclohexyl]amino]-2-methyl-5-(3-morpholin-4-ylprop-1-ynyl)benzamide; 2,2,2-trifluoroacetic acidEPZ011989 (trifluoroacetate). CAS No. 1598383-41-5. Molecular formula: C37H52F3N5O6. Mole weight: 719.83.
FAK-IN-1
FAK-IN-1 is an inhibitor of FAK with anticancer activities. (Extracted from patent WO2020231726, Example 27). Synonyms: 10H-Pyrimido[5,4-b]thiazolo[5,4-e][1,4]diazepin-10-one, 4,9-dihydro-2,4,9-trimethyl-6-[(1,2,3,4-tetrahydro-6-methoxy-2-methyl-7-isoquinolinyl)amino]-, 2,2,2-trifluoroacetate (1:1). CAS No. 2553215-22-6. Molecular formula: C24H26F3N7O4S. Mole weight: 565.57.
Filanesib TFA
Filanesib TFA is a selective inhibitor of kinesin spindle protein (KSP) (IC50 = 6 nM for human KSP), with potent anti-proliferative activity. It induces cell death by apoptosis in vitro. Synonyms: ARRY-520 TFA; (2S)-2-(3-Aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3(2H)-carboxamide trifluoroacetate; Acetic acid, 2,2,2-trifluoro-, compd. with (2S)-2-(3-aminopropyl)-5-(2,5-difluorophenyl)-N-methoxy-N-methyl-2-phenyl-1,3,4-thiadiazole-3(2H)-carboxamide (1:1). CAS No. 1781834-99-8. Molecular formula: C22H23F5N4O4S. Mole weight: 534.50.
FTI 277 is a prodrug form of FTI 276 that inhibits farnesyltransferase (FTase) (IC50 = 0.5 nM) with antiproliferative activity. It potently inhibits H-Ras and K-Ras processing in whole cells (IC50 = 0.1 and 10 μM, respectively) and disrupts constitutive H-Ras-specific activation of MAPK. Synonyms: FTI 277 trifluoroacetate salt; FTI277 trifluoroacetate salt; FTI-277 trifluoroacetate salt; N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt. Grade: ≥95% by HPLC. CAS No. 1217447-06-7. Molecular formula: C22H29N3O3S2.C2HF3O2. Mole weight: 561.64.
Galnon TFA
Galnon is a non-peptide galanin GAL1 and GAL2 receptor agonist (Ki = 11.7 and 34.1 μM, respectively) with anticonvulsant, anxiolytic, anorectic and amnestic activities. It stimulates insulin release in isolated pancreatic islets from normal and diabetic rats. Synonyms: L-Lysinamide, 3-cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-, 2,2,2-trifluoroacetate (1:1); Fmoc-Cha-Lys-AMC.TFA; 3-Cyclohexyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-lysinamide trifluoroacetate salt; Galnon trifluoroacetate salt; Galnon Trifluoroacetate. Grade: ≥95%. CAS No. 1217448-19-5. Molecular formula: C40H46N4O6.C2HF3O2. Mole weight: 792.84.
Gardiquimod TFA
Gardiquimod is a chemical compound which acts selectively at both mouse and human forms of toll-like receptor 7 (TLR7). It functions as an immune response modifier. The core structure is 1H-imidazo[4,5-c]quinoline, as found in related drugs such as imiquimod and resiquimod. It is structurally very similar to resiquimod differing only by an oxygen for nitrogen switch. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Gardiquimod TFA salt; Gardiquimod. Product Category: Others. Appearance: Solid powder. CAS No. 1159840-61-5. Molecular formula: C19H24F3N5O3. Mole weight: 427.43. Purity: >98%. IUPACName: 1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol 2,2,2-trifluoroacetate. Canonical SMILES: CC(O)(C)CN1C(CNCC)=NC2=C1C3=CC=CC=C3N=C2N.O=C(O)C(F)(F)F. Product ID: ACM1159840615. Alfa Chemistry ISO 9001:2015 Certified. Categories: Gardiquimod trifluoroacetate.
GGTI 286 trifluoroacetate salt
GGTI 286 is a cell permeable and potent inhibitor of geranylgeranyltransferase I (GGTase I) that selectively inhibits geranylgeranylation of Rap1A over farnesylation of H-Ras in NIH3T3 cells (IC50s = 2 and >30 μM, respectively). Synonyms: N-[[5-[[(2R)-2-amino-3-mercaptopropyl]amino][1,1'-biphenyl]-2-yl]carbonyl]-L-leucine, methyl ester, trifluoroacetate salt. Grade: ≥90%. Molecular formula: C23H31N3O3S·2CF3COOH. Mole weight: 657.62.
GGTI 298 (trifluoroacetate salt)
GGTI-298 is a selective geranylgeranyltransferase type I inhibitor that displays little effect on other prenylation enzymes such as farnesyltransferase. GGTI-298 causes G0-G1 cell cycle block and apoptosis in A549 cells (IC50 = 10 μM for A549 cells) and inhibits cell invasion and migration in COLO 320CM cells. Synonyms: methyl (4-(((R)-2-amino-3-mercaptopropyl)amino)-2-(naphthalen-1-yl)benzoyl)-L-leucinate 2,2,2-trifluoroacetate; GGTI-298 TFA; GGTI-298 trifluoride salt; GGTI-298; GGTI 298; GGTI298. CAS No. 1217457-86-7. Molecular formula: C27H33N3O3S.CF3COOH. Mole weight: 593.7.
GSK121 trifluoroacetate salt
GSK121 is an inhibitor for protein arginine deiminase 4 (PAD4), which has been shown to inhibit the citrullination of PAD4 target proteins in a functional assay with an IC50 value of 3.2 μM. Synonyms: (3-amino-1-piperidinyl)[1-methyl-2-(1-methyl-1H-indol-2-yl)-1H-benzimidazol-5-yl]-methanone, 2,2,2-trifluoroacetate. Grade: ≥98%. CAS No. 1652591-80-4. Molecular formula: C23H25N5O·CF3COOH. Mole weight: 501.5.
GSK2807 Trifluoroacetate
GSK2807 Trifluoroacetate is a potent, selective and SAM-competitive SMYD3 inhibitor, with a Ki of 14 nM and an IC50 of 130 nM. Synonyms: (S)-2-Amino-4-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(3-(dimethylamino)propyl)amino)butanoic acid 2,2,2-trifluoroacetic acid; 5'-{[(3S)-3-Amino-3-carboxypropyl][3-(dimethylamino)propyl]amino}-5'-deoxyadenosine trifluoroacetate (1:1); Acetic acid, 2,2,2-trifluoro-, compd. with adenosine, 5'-[[(3S)-3-amino-3-carboxypropyl][3-(dimethylamino)propyl]amino]-5'-deoxy- (1:1). Grade: ≥95%. CAS No. 2245255-66-5. Molecular formula: C21H33F3N8O7. Mole weight: 566.53.
H-Met-Trp-OH TFA salt is an incomplete breakdown product of protein digestion or protein catabolism. It is a non-competitive inhibitor of angiotensin-1 converting enzyme (ACE). Synonyms: H-Met-Trp-OH Trifluoroacetate salt; L-methionyl-L-tryptophan trifluoroacetic acid; (S)-2-((S)-2-Amino-4-(methylthio)butanamido)-3-(1H-indol-3-yl)propanoic acid compound with 2,2,2-trifluoroacetic acid (1:1). Molecular formula: C16H21N3O3S.C2HF3O2. Mole weight: 449.45.
L-Alanine-7-amido-4-methylcoumarin trifluoroacetic acid salt
L-Alanine-7-amido-4-methylcoumarin trifluoroacetic acid salt is a Fluorogenic substrate for aminopeptidase. Synonyms: L-Alanine-AMC TFA salt; H-ALA-AMC TFA; L-Alanine 7-amido-4-methylcoumarin trifluoroacetate salt; (2S)-2-Amino-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-propanamide 2,2,2-trifluoroacetate. Grade: ≥95%. CAS No. 96594-10-4. Molecular formula: C15H15F3N2O5. Mole weight: 360.29.