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(2R)-2-[(2R)-1-[Bis(4-methoxyphenyl)-phenylmethoxy]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxypropan-2-yl]oxy-2-[2-(2-methylpropanoylamino)-6-oxo-1H-purin-9-yl]ethyl] benzoate is a uniquely intricate compound possessing potential applications in the realm of cancer therapeutics. Possessing potent antineoplastic capabilities, it demonstrates high efficacy in the research of obstruction in malignant cellular proliferation. Synonyms: N2-Isobutyryl-(5'-(4,4'-dimethoxytrityl)-2'-benzoyl-2',3'-seco-guanosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)] phosphoramidite. CAS No. 1120329-61-4. Molecular formula: C51H60N7O10P. Mole weight: 962.
(2S) ?-?1-? (2-?methylpropanoyl) ?pyrrolidine-?2-?carboxylic Acid (Captopril EP Impurity E) is an impurity of Captopril (C175750), an orally active angiotensin-converting enzyme (ACE) inhibitor(1) which acts as a neuroprotective & neuroresearch product. Group: Biochemicals. Grades: Highly Purified. CAS No. 23500-15-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C9H15NO3, Molecular Weight: 185.22. US Biological Life Sciences.
Contains thiamine diphosphate. It acts not only on 3-methyl-2-oxobutanaoate, but also on 4-methyl-2-oxopentanoate and (S)-3-methyl-2-oxopentanoate, so that it acts on the 2-oxo acids that derive from the action of transaminases on valine, leucine and isoleucine. It is a component of the multienzyme 3-methyl-2-oxobutanoate dehydrogenase complex in which multiple copies of it are bound to a core of molecules of EC 2.3.1.168, dihydrolipoyllysine-residue (2-methylpropanoyl)transferase, which also binds multiple copies of EC 1.8.1.4, dihydrolipoyl dehydrogenase. It does not act on free lipoamide or lipoyllysine, but only on the lipoyllysine residue in EC 2.3.1.168. Group: Enzymes. Synonyms: 2-oxoisocaproate dehydrogenase; 2-oxoisovalerate (lipoate) dehydrogenase; 3-methyl-2-oxobutanoate dehydrogenase (lipoamide); 3-methyl-2-oxobutanoate:lipoamide oxidoreductase (decarboxylating and acceptor-2-methylpropanoylating); α-keto-α-methylvalerate dehydrogenase; α. Enzyme Commission Number: EC 1.2.4.4. CAS No. 9082-72-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1219; 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); EC 1.2.4.4; 9082-72-8; 2-oxoisocaproate dehydrogenase; 2-oxoisovalerate (lipo
A multimer (24-mer) of this enzyme forms the core of the multienzyme 3-methyl-2-oxobutanoate dehydrogenase complex, and binds tightly both EC 1.2.4.4, 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) and EC 1.8.1.4, dihydrolipoyl dehydrogenase. The lipoyl group of this enzyme is reductively 2-methylpropanoylated by EC 1.2.4.4, and the only observed direction catalysed by EC 2.3.1.168 is that where this 2-methylpropanoyl is passed to coenzyme A. In addition to the 2-methylpropanoyl group, formed when EC 1.2.4.4 acts on the oxoacid that corresponds with valine, this enzyme also transfers the 3-methylbutanoyl and S-2-methylbutanoyl groups, donated to it when EC 1.2.4.4 acts on the oxo acids corresponding with leucine and isoleucine. Group: Enzymes. Synonyms: dihydrolipoyl transacylase; enzyme-dihydrolipo. Enzyme Commission Number: EC 2.3.1.168. CAS No. 102784-26-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2108; dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; EC 2.3.1.168; 102784-26-9; dihydrolipoyl transacylase; enzyme-dihydrolipoyllysine:2-methylpropanoyl-CoA S-(2-methylpropanoyl)transferase; 2-methylpropanoyl-CoA:enzyme-6-N-(dihydrolipoyl)lysine S-(2-methylpropanoyl)transferase. Cat No: EXWM-2108.
A deuterated homolog of Tiopronin. Group: Biochemicals. Alternative Names: 3-Mercapto-2-methyl-propionylamino)-acetic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
1,1,1-Tris(2-bromoisobutyryloxymethyl)ethane
Atom Transfer Radical Polymerization (ATRP) initiator for the creation of trifunctional polymers. Polymerization will occur at three sites creating a three-arm star polymer. Group: Polymer/macromolecule. Alternative Names: 3f-BiB, Trifunctional initiator. CAS No. 648898-32-2. Molecular formula: C17H27Br3O6. Mole weight: 567.1. Purity: 0.96. IUPACName: [3-(2-bromo-2-methylpropanoyl)oxy-2-[(2-bromo-2-methylpropanoyl)oxymethyl]-2-methylpropyl] 2-bromo-2-methylpropanoate. Canonical SMILES: CC (C) (Br)C (=O)OCC (C) (COC (=O)C (C) (C)Br)COC (=O)C (C) (C)Br. Catalog: ACM648898322-1.
1-[(2R)-3-Mercapto-2-methyl-1-oxopropyl]-D-proline is an impurity of Captopril, which is an orally active angiotensin-converting enzyme (ACE) inhibitor used as an antihypertensive agent. Synonyms: (R)-1-(3-Mercapto-2-methyl-1-oxopropyl)-D-proline; 1-(D-3-mercapto-2-methylpropionyl)-L-proline; Captopril Related Compound 8; epi-D-captopril; (R)-1-((R)-3-Mercapto-2-methyl-propionyl)-pyrrolidine-2-carboxylic acid; (2R)-1-((2R)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylic acid; ((R)-3-mercapto-2-methylpropanoyl)-D-proline. Grades: 98%. CAS No. 112243-88-6. Molecular formula: C9H15NO3S. Mole weight: 217.28.
1-Oxo Ibuprofen
1-Oxo Ibuprofen, is a degradation product of Ibuprofen arising from oxidative and thermal treatments. 1-Oxo Ibuprofen is the Ibuprofen impurity J. Group: Biochemicals. Alternative Names: α -Methyl-4- (2-methyl-1-oxopropyl) benzeneacetic Acid; 2- (4-Isobutyrylphenyl) propionic acid; (2RS) -2-[4- (2-Methylpropanoyl) phenyl] propanoic acid; a-Methyl-4- (2-methyl-1-oxopropyl) benzeneacetic acid; Impurity J. Grades: Highly Purified. CAS No. 65813-55-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
1-Oxo Ibuprofen
1-Oxo Ibuprofen. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Ibuprofen USP Related Compound J, Ibuprofen USP RC J, Ibuprofen Imp. J (EP),(2RS)-2-[4-(2-Methyl-propanoyl)phenyl]propanoic Acid. CAS No. 65813-55-0. IUPAC Name: 2-[4-(2-methylpropanoyl)phenyl]propanoic acid. Molecular Formula: C13H16O3. Mole Weight: 220.26. Catalog: APS65813550. SMILES: CC(C)C(=O)c1ccc(cc1)C(C)C(=O)O. Format: Neat.
1-[ (S) -3- (Acetylthio) isobutyryl]-L-proline Hydrate
1-[ (S) -3- (Acetylthio) isobutyryl]-L-proline Hydrate. Group: Biochemicals. Alternative Names: DU 1163; S-Acetylcaptopril Hydrate; (S)-1-[3-(Acetylthio)-2-methyl-1-oxopropyl]-L-proline Hydrate; (S,S)-1-(D-3-Acetylthio-2-methylpropanoyl)-L-proline Hydrate. Grades: Highly Purified. CAS No. 64838-55-7. Pack Sizes: 100mg. Molecular Formula: C11H17NO4S, Molecular Weight: 259.32. US Biological Life Sciences.
Worldwide
2,2,4-Trimethyl-1,3-pentanediol diisobutyrate
Flavor and Fragrance Standards; Food Contact Materials; Standards for Food Regulatory Methods. Uses: For analytical and research use. Group: Reagents. Grades: analytical standard. CAS No. 6846-50-0. Pack Sizes: 1ML. IUPAC Name: [2,2,4-trimethyl-3-(2-methylpropanoyloxy)pentyl] 2-methylpropanoate.
The enzyme has no activating compound but is specific for its substrate. It is a mitochondrial enzyme associated with the branched-chain 2-oxoacid dehydrogenase complex. Phosphorylation inactivates EC 1.2.4.4, 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring). Group: Enzymes. Synonyms: BCK; BCKD kinase; BCODH kinase; branched-chain α-ketoacid dehydrogenase kinase; branched-chain 2-oxo acid dehydrogenase kinase; branched-chain keto acid dehydrogenase kinase; branched-chain oxo acid dehydrogenase kinase (phosphorylating); STK2. Enzyme Commission Number: EC 2.7.11.4. CAS No. 82391-38-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3155; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase; EC 2.7.11.4; 82391-38-6; BCK; BCKD kinase; BCODH kinase; branched-chain α-ketoacid dehydrogenase kinase; branched-chain 2-oxo acid dehydrogenase kinase; branched-chain keto acid dehydrogenase kinase; branched-chain oxo acid dehydrogenase kinase (phosphorylating); STK2. Cat No: EXWM-3155.
5'-O-DMT-N4-Isobutyryl-2'-deoxycytidine-3'-CE Phosphoramidite, a chemical reagent widely employed in oligonucleotide synthesis for biomedical research, manifests remarkable versatility in targeting a wide range of ailments, spanning from cancer to genetic disorders. With its ready availability and proven efficacy in in-vitro experiments, this chemical reagent is the go-to choice for generating novel and effective therapeutic oligonucleotides. Synonyms: IBU-DC Phosphoramidite; 5'-O-[Bis (4-methoxyphenyl) (phenyl)methyl]-3'-O-[ (2-cyanoethoxy) (diisopropylamino)phosphino]-2'-deoxy-N-isobutyrylcytidine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-2'-deoxy-N-(2-methylpropanoyl)cytidine; N-Isobutyryl-3'-O-[ (2-cyanoethoxy) (diisopropylamino)phosphino]-5'-O- (4, 4'-dimethoxytrityl)-2'-deoxycytidine; IBU-dC CEP. Grades: ≥98% by HPLC. CAS No. 110522-84-4. Molecular formula: C43H54N5O8P. Mole weight: 799.90.
8-Benzyloxy-N2-isobutyryl-2'-deoxyguanosine
8-Benzyloxy-N2-isobutyryl-2'-deoxyguanosine is an antiviral compound, holding immense potential in the development of antiviral therapeutics. Synonyms: N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-oxo-8-phenylmethoxy-1H-purin-2-yl]-2-methylpropanamide; 8-BENZYLOXY-N2-ISOBUTYRYL-2/'-DEOXYGUANOSINE;8-(Benzyloxy)-2'-deoxy-N-(2-methylpropanoyl)guanosine; N-(8-(benzyloxy)-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide. Grades: ≥ 90%. CAS No. 136859-75-1. Molecular formula: C21H25N5O6. Mole weight: 443.46.
8-Oxo-N2-isobutyryl-2'-deoxyguanosine
8-Oxo-N2-isobutyryl-2'-deoxyguanosine is an exceptional biomedical compound, rendered as a discerning indicator for DNA impairment. It assumes an integral role as a substrate for DNA reparation. Its utilization propels extensive investigation into oxidative species-induced DNA lesions, thereby furnishing profound elucidation into an array of afflictions spanning cancer to neurodegenerative disorders. Synonyms: 8-HYDROXY-N2-ISOBUTRYL-2'-DEOXYGUANOSINE; 8-HYDROXY-N2-ISOBUTRYL-2/'-DEOXYGUANOSINE; N-[9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,8-dioxo-1,7-dihydropurin-2-yl]-2-methylpropanamide; DTXSID40721580; MFCD22373349; N2-Isobutyryl-8-oxo-2'-deoxyguanosine; 2'-Deoxy-N-(2-methylpropanoyl)-8-oxo-7,8-dihydroguanosine; N-(8-hydroxy-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide. Grades: ≥ 90%. CAS No. 136859-76-2. Molecular formula: C14H19N5O6. Mole weight: 353.33.
Alamethicin (Antibiotic U-22324)
Alamethicin is a peptide antibiotic, produced by the fungus Trichoderma viride. Alamethicin contains the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib), which strongly induces helical peptide structures. In cell membranes, it forms voltage-dependent ion channels by aggregation of four to six molecules. Group: Biochemicals. Alternative Names: (3S,12R)-1-((S)-1-((6S,12S,15S,21S,30S)-1-((R)-1-(2-Acetamido-2- methylpropanoyl) pyrrolidin-2-yl) -15- (3-amino-3-oxopropyl) -30-isobutyl-21-isopropyl- 3, 3, 6, 9, 9, 2, 18, 18, 24, 24, 33, 33-dodecamethyl-1, 4, 7, 10, 13, 16, 19, 22, 25, 28, 31- undecaoxo-2, 5, 8, 11, 14, 17, 20, 23, 26, 29, 32-undecaazatetratri acontan-34- oyl)pyrrolidin-2-yl)-12-(((R)-5-amino-1-(((S)-1-hydroxy-3-phenylpropan-2-yl)amino)-1, 5-dioxopentan-2-yl)carbamoyl)-3-isopropyl-6,6,9,9-tetramethyl-1,4,7,10-tetraoxo-2,5, 8,11-tetraazapentadecan-15-oic Acid; Antibiotic U-22324. Grades: Purified. CAS No. 27061-78-5. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C??H???N??O??, Molecular Weight: 1964.31. US Biological Life Sciences.
Worldwide
Atorvastatin Epoxydione Impurity
Atorvastatin Epoxydione Impurity. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Atorvastatin USP RC D, Atorvastatin USP Related Compound D, Atorvastatin Imp. D (EP), 3-[(4-Fluorophenyl)carbonyl]-2-(2-methylpropanoyl)-N,3-diphenyloxirane-2-carboxamide,Atorvastatin Calcium Trihydrate Imp. D (EP). CAS No. 148146-51-4. IUPAC Name: 3-(4-fluorobenzoyl)-2-(2-methylpropanoyl)-N,3-diphenyloxirane-2-carboxamide. Molecular Formula: C26H22FNO4. Mole Weight: 431.46. Catalog: APS148146514. SMILES: CC (C)C (=O)C1 (OC1 (C (=O)c2ccc (F)cc2)c3ccccc3)C (=O)Nc4ccccc4. Format: Neat.
Bezafibrate Acyl Glucuronide
Bezafibrate Acyl Glucuronide. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,3S,4S,5R,6S)-6-((2-(4-(2-(4-chlorobenzamido)ethyl)phenoxy)-2-methylpropanoyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid. CAS No. 72156-77-5. Molecular Formula: C25H28ClNO10. Mole Weight: 537.95. Catalog: APB72156775.
Atom transfer Radical Polymerisation (ATRP) initiator commonly used to functionalize noble metal surfaces, and in the preparation of polymer brushes and biodegradable hydrogels. Also may be used to introduce a temperature and light sensitive cleavable region into the polymer. Group: Heterocyclic organic compound. Alternative Names: 11,11'-Dithiobis[1-(2-bromo-2-methylpropionyloxy)undecane], DTBU. CAS No. 402828-41-5. Molecular formula: C30H56Br2O4S2. Mole weight: 704.7. Purity: 0.96. IUPACName: 11-[11- (2-bromo-2-methylpropanoyl) oxyundecyldisulfanyl]undecyl 2-bromo-2-methylpropanoate. Canonical SMILES: CC (C) (Br)C (=O)OCCCCCCCCCCCSSCCCCCCCCCCCOC (=O)C (C) (C)Br. Density: 1.177 g/mL at 25 °C. Catalog: ACM402828415-1.
Bis[2-(2-bromoisobutyryloxy)undecyl] disulfide
Bis[2-(2-bromoisobutyryloxy)undecyl] disulfide. Uses: Atom transfer radical polymerisation (atrp) initiator commonly used to functionalize noble metal surfaces, and in the preparation of polymer brushes and biodegradable hydrogels. also may be used to introduce a temperature and light sensitive cleavable region into the polymer. Group: Self-assembly materials. Alternative Names: 11,11'-Dithiobis[1-(2-bromo-2-methylpropionyloxy)undecane], DTBU. CAS No. 402828-41-5. Pack Sizes: Packaging 500 mg in glass insert. Product ID: 11-[11- (2-bromo-2-methylpropanoyl) oxyundecyldisulfanyl]undecyl 2-bromo-2-methylpropanoate. Molecular formula: 704.70. Mole weight: C30H56Br2O4S2. CC (C) (Br)C (=O)OCCCCCCCCCCCSSCCCCCCCCCCCOC (=O)C (C) (C)Br. 1S / C30H56Br2O4S2 / c1-29 (2, 31) 27 (33) 35-23-19-15-11-7-5-9-13-17-21-25-37-3 8-26-22-18-14-10-6-8-12-16-20-24-36-2 8 (34) 30 (3, 4) 32 / h5-26H2, 1-4H3. IEGYEGYUHSQEAZ-UHFFFAOYSA-N. 96%.
Captopril EP Impurity B is an impurity of Captopril, which is an orally active angiotensin-converting enzyme (ACE) inhibitor used as an antihypertensive agent. Synonyms: 1-[(2S)-3-Bromo-2-methyl-1-oxopropyl]-L-proline; (S)-1-(3-bromo-2-methyl-1-oxopropyl)-L-proline; Captopril impurity B; (S)-1-((S)-3-bromo-2-methylpropanoyl)pyrrolidine-2-carboxylic acid; Captopril Impurity 2; L-Proline, 1-(3-bromo-2-methyl-1-oxopropyl)-, (S)-. Grades: ≥95%. CAS No. 80629-35-2. Molecular formula: C9H14BrNO3. Mole weight: 264.12.
Captopril EP Impurity E
an impurity of Captopril. Synonyms: (2S)-1-(2-Methylpropanoyl)pyrrolidine-2-carboxylic acid, 1-Isobutyryl-L-proline. Grades: > 95%. CAS No. 23500-15-4. Molecular formula: C9H15NO3. Mole weight: 185.22.
Captopril EP Impurity H
Captopril EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-1-((S)-3-(((R)-3-(acetylthio)-2-methylpropanoyl)thio)-2-methylpropanoyl)pyrrolidine-2-carboxylic acid. CAS No. 205521-07-9. Molecular Formula: C15H23NO5S2. Mole Weight: 361.48. Catalog: APB205521079.
Captopril EP Impurity I
Captopril EP Impurity I. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-1-((S)-3-(((S)-1-((S)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carbonyl)thio)-2-methylpropanoyl)pyrrolidine-2-carboxylic acid. Molecular Formula: C18H28N2O5S2. Mole Weight: 416.56. Catalog: APB04584.
Captopril Impurity 2
Captopril Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-1-((R)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylic acid. CAS No. 112243-88-6. Molecular Formula: C9H15NO3S. Mole Weight: 217.29. Catalog: APB112243886.
Captopril-N-acetylcysteine Disulfide
Captopril-N-acetylcysteine Disulfide is a metabolite of Captopril, which is an orally active angiotensin-converting enzyme (ACE) inhibitor used as an antihypertensive agent. Synonyms: 1-[(2S)-3-[[(2R)-2-(Acetylamino)-2-carboxyethyl]dithio]-2-methyl-1-oxopropyl]-L-proline; ((S)-3-(((R)-2-acetamido-2-carboxyethyl)disulfaneyl)-2-methylpropanoyl)-L-proline; 1-[(2S)-3-{[(2R)-2-Acetamido-2-carboxyethyl]disulfanyl}-2-methylpropanoyl]-L-proline; Captopril Related Compound 10. Grades: 95%. CAS No. 78636-31-4. Molecular formula: C14H22N2O6S2. Mole weight: 378.46.
Cohumulone
Cohumulone is one of three major analogues of hop a-acids, the others being adhumulone and humulone. Synonyms: Cohumulone; 511-25-1; 142628-20-4; 2Y34G4NIC8; (+/-)-cohumulone; 3,5,6-trihydroxy-4,6-bis(3-methylbut-2-enyl)-2-(2-methylpropanoyl)cyclohexa-2,4-dien-1-one; 5-(alpha,beta-Dibromophenethyl)-5-methylhydantoin; UNII-2Y34G4NIC8; 2,5-Cyclohexadien-1-one, 3,4,5-trihydroxy-2-isobutyryl-4,6-bis(3-methyl-2-butenyl)-; COHUMULONE, (-)-; SCHEMBL317724; SCHEMBL13629034; GTPL12422; DTXSID20931549; CHEBI:175443; DRSITEVYZGOOQG-UHFFFAOYSA-N; DTXSID701318500; Q2981886; Q27893896; (-)-3,4,5-TRIHYDROXY-2,4-BIS(3-METHYL-2-BUTEN-1-YL)-6-(2-METHYL-1-OXOPROPYL)-2,5-CYCLOHEXADIEN-1-ONE; 2,5-CYCLOHEXADIEN-1-ONE, 3,4,5-TRIHYDROXY-2,4-BIS(3-METHYL-2-BUTEN-1-YL)-6-(2-METHYL-1-OXOPROPYL)-, (-)-; 3,4,5-Trihydroxy-2,4-bis(3-methyl-2-butenyl)-6-(2-methyl-1-oxopropyl)-2,5-cyclohexadien-1-one, 9CI; 3,5,6-TRIHYDROXY-4,6-BIS(3-METHYLBUT-2-EN-1-YL)-2-(2-METHYLPROPANOYL)CYCLOHEXA-2,4-DIEN-1-ONE. Grades: > 95%. CAS No. 511-25-1. Molecular formula: C20H28O5. Mole weight: 348.44.
ATRP for Everyone: Ligands and Initiators for the Clean Synthesis of Functional Polymers. Group: Polymer/macromolecule. Alternative Names: Difunctional initiator, 1,2-Bis(2'-bromoisobutyryloxy)ethane, 2f-BiB. CAS No. 248603-11-4. Molecular formula: C10H16Br2O4. Mole weight: 360.04. Purity: 0.96. IUPACName: 2-(2-bromo-2-methylpropanoyl)oxyethyl 2-bromo-2-methylpropanoate. Canonical SMILES: CC(C)(Br)C(=O)OCCOC(=O)C(C)(C)Br. Catalog: ACM248603114-1.
Faldaprevir
Faldaprevir, also called as BI 201335, is a potent, once-daily (QD), hepatitis C virus (HCV) NS3/4A protease inhibitor with the potential to treat HCV infection. Faldaprevir (BI 201335) is undergoing testing in a Phase II clinical study in Hepatitis C released by Trek Therapeutics. Synonyms: Faldaprevir; BI-201335; BI 201335; BI201335; (1S,2R)-1-[[(2S,4R)-4-[8-bromo-7-methoxy-2-[2-(2-methylpropanoylamino)-1,3-thiazol-4-yl]quinolin-4-yl]oxy-1-[(2S)-2-(cyclopentyloxycarbonylamino)-3,3-dimethylbutanoyl]pyrrolidine-2-carbonyl]amino]-2-ethenylcyclopropane-1-carboxylic acid; BI 201335; BI-201335; BI201335; faldaprevir; N-((cyclopentyloxy)carbonyl)-3-methylvalyl-4-((8-bromo-7-methoxy-2-(2-((2-methylpropanoyl)amino)-1,3-thiazol-4-yl)quinolin-4-yl)oxy)-N-(1-carboxy-2-ethenylcyclopropyl)prolinamide. Grades: ≥98% (HPLC). CAS No. 801283-95-4. Molecular formula: C40H49BrN6O9S. Mole weight: 869.84.
FL-120A
FL-120A is produced by the strain of Streptomyces chattanoogensis subsp. taitungessis. It has anti-Gram-positive aerobes and anaerobe activity. Synonyms: FL-120-A; 1,3-Bis(acetyloxy)-11-diazonio-4,9-dihydroxy-2-methyl-2-[(2-methylpropanoyl)oxy]-10-oxo-2,3,4,10-tetrahydro-1H-benzo[b]fluoren-5-olate. CAS No. 156429-10-6. Molecular formula: C26H24N2O10. Mole weight: 524.48.
FL-120B
FL-120B is produced by the strain of Streptomyces chattanoogensis subsp. taitungessis. It has anti-Gram-positive aerobes and anaerobe activity. Synonyms: 9-Diazonio-2,7-dihydroxy-10a-methyl-10-[(2-methylpropanoyl)oxy]-8-oxo-2,8,10,10a-tetrahydro-1aH-benzo[6,7]fluoreno[2,3-b]oxiren-3-olate. CAS No. 156429-11-7. Molecular formula: C22H18N2O7. Mole weight: 422.39.
FR-181074
FR-181074 may be a bio-active chemical to treat Male Sexual Dysfunction. Synonyms: 1-[(2-chlorophenyl)methyl]-3-(2-methylpropanoyl)-2-propylindole-6-carboxamide; FR-181074; FR181074; FR 181074; UNII-D3C5RV093V. Grades: >98%. CAS No. 184147-65-7. Molecular formula: C23H25ClN2O2. Mole weight: 396.91.
Hyperforin is produced by the strain of Hypericum perforatum. It has anti-gram-positive bacterial and mycobacterium activity. Synonyms: hiperforina; hyperforine; (1R,5S,6R,7S)-4-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-en-1-yl)-6-(4-methylpent-3-en-1-yl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-3-ene-2,9-dione; Bicyclo[3.3.1]non-3-ene-2,9-dione, 4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-, (1R,5S,6R,7S)-. Grades: >95%. CAS No. 11079-53-1. Molecular formula: C35H52O4. Mole weight: 536.78.
Isobutyryl-L-carnitine is a product of acyl-CoA dehydrogenases (ACADs) of the acylcarnitine class. Synonyms: L-Isobutyrylcarnitine; (3R)-3-(2-methylpropanoyloxy)-4-(trimethylazaniumyl)butanoate. Grades: ≥95%. CAS No. 25518-49-4. Molecular formula: C11H21NO4. Mole weight: 231.3.
LY-281217
LY-281217 is an organic opioid agonist. It can produce analgesic effects in mice. Uses: Ly-281217 can produce analgesic effects. Synonyms: LY 281217; LY281217; LY-281217. N,N-Di(2-propenyl)-L-Tyr-2-methyl-Ala-2-methyl-Ala-L-Phe-OH;N-[N-[N-(N,N-Di-2-propenyl-L-tyrosyl)-2-methylalanyl]-2-methylalanyl]-L-phenylalanine;(2S)-2-[[2-[[2-[[(2S)-2-[bis(prop-2-enyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]-2-methylpropanoyl]amino]-2-methylpropanoyl]amino]-3-phenylpropanoic acid;LY281217;L-Phenylalanine, N-(N-(N-(N,N-di-2-propenyl-L-tyrosyl)-2-methylalanyl)-2-methylalanyl)-. Grades: >99 %. CAS No. 105027-75-6. Molecular formula: C32H42N4O6. Mole weight: 578.71.
MMAF Hydrochloride
MMAF Hydrochloride, a synthetic antineoplastic agent, is a tubulin polymerization inhibitor that inhibits cell division by blocking the polymerization of tubulin. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. Uses: Adcs cytotoxin. Synonyms: Monomethylauristatin F Hydrochloride; Monomethyl Auristatin F Hydrochloride; N-Methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine Hydrochloride; Monomethylauristatin Phenylalanine Hydrochloride; L-Valinamide, N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-, Hydrochloride (1:1); ((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine Hydrochloride. Grades: >98%. CAS No. 1415246-68-2. Molecular formula: C39H66ClN5O8. Mole weight: 768.42.
N2-iso-Butyroyl-3'-deoxyguanosine
N2-Iso-Butyroyl-3'-deoxyguanosine is an esteemed product from the biomedical realm significantly sought-after for its potential antiviral attributes. It aids in studying viral afflictions such as HIV and hepatitis B. Synonyms: 3'-Deoxy-N-(2-methylpropanoyl)guanosine; N-(9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide; Guanosine, 3'-deoxy-N-(2-methyl-1-oxopropyl)-; 3'-Deoxy-N-isobutyrylguanosine. Grades: ≥95%. CAS No. 157025-66-6. Molecular formula: C14H19N5O5. Mole weight: 337.33.
N-Isobutyrylguanosine
N-Isobutyrylguanosine is used in the syntehsis of 2'-O-(o-nitrobenzyl)-3'-thioguanosine phosphoramidite which is then used to form oligonucleotides, substrates for probing the mechanism of RNA catalysis. Synonyms: N2-iso-Butyrylguanosine; N2-Isobutyrylguanosine; N-(2-methylpropanoyl)guanosine; N-(2-Methyl-1-oxopropyl)guanosine; N-(9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-2-methylpropanamide. Grades: ≥ 95 %. CAS No. 64350-24-9. Molecular formula: C14H19N5O6. Mole weight: 353.33.
O-Demethylpaulomycin B
O-Demethylpaulomycin B is a quinone antibiotic produced by Streptomyces paulus. It has the effect of anti-gram-positive bacteria, and its activity is lower than that of Pauloycin. Synonyms: 5-[6-(acetyloxymethyl)-4-[4,5-dihydroxy-6-methyl-5-[1-(2-methylpropanoyloxy)ethyl]oxan-2-yl]oxy-3-hydroxy-5-[(E)-2-isothiocyanatobut-2-enoyl]oxyoxan-2-yl]-2-amino-5-hydroxy-3,6-dioxocyclohexene-1-carboxylic acid; 1-Cyclohexene-1-carboxylic acid, 5-(6-O-acetyl-3-O-(2,6-dideoxy-4-C-((S)-1-(2-methyl-1-oxopropoxy)ethyl)-alpha-L-lyxo-hexopyranosyl)-4-O-(2-isothiocyanato-1-oxo-2-butenyl)-beta-D-allopyranosyl)-2-amino-5-hydroxy-3,6-dioxo-, (S)-. CAS No. 113592-08-8. Molecular formula: C32H42N2O17S. Mole weight: 758.74.
Paldimycin
It is produced by the strain of Str. paulus 273. It has anti-gram-positive bacterial effect, but also has weak anti-gram-negative bacterial effect. Paldimycin A has stronger antibacterial activity than Paldimycin B. Synonyms: Antibiotic 273 A1; (5S) -5- [5- [3- [ (2R) -2-acetamido-2-carboxyethyl] sulfanyl-2- [ [ (2R) -2-acetamido-2-carboxyethyl] sulfanylcarbothioylamino] butanoyl] oxy-6- (acetyloxymethyl) -3-hydroxy-4- [5-hydroxy-4-methoxy-6-methyl-5- [ (1S) -1- (2-methylpropanoyloxy) ethyl] oxan-2-yl] oxyoxan-2-yl] -2-amino-5-hydroxy-3, 6-dioxocyclohexene-1-carboxylic acid; (5S) -5- [5- [3- [ (2R) -2-acetamido-2-carboxyethyl] sulfanyl-2- [ [ (2R) -2-acetamido-2-carboxyethyl] sulfanylcarbothioylamino] butanoyl] oxy-6- (acetyloxymethyl) -3-hydroxy-4- [5-hydroxy-4-methoxy-6-methyl-5- [ (1S) -1- [ (2S) -2-methylbutanoyl] oxyethyl] oxan-2-yl] oxyoxan-2-yl] -2-amino-5-hydroxy-3, 6-dioxocyclohexene-1-carboxylic acid. CAS No. 102426-96-0. Molecular formula: C87H126N8O46S6. Mole weight: 2212.34.
Ranolazine 2,3,4-Tri-O-isobutyryl-β-D-Glucuronide Methyl Ester (mixture of diastereomers)
Ranolazine 2,3,4-Tri-O-isobutyryl-β-D-Glucuronide Methyl Ester (mixture of diastereomers) is a derivative of Ranolazine, which is a medication used to treat heart-related chest pain. Synonyms: methyl (2S,3S,4S,5R,6R)-6-[1-[4-[2-(2,6-dimethylanilino)-2-oxoethyl]piperazin-1-yl]-3-(2-methoxyphenoxy)propan-2-yl]oxy-3,4,5-tris(2-methylpropanoyloxy)oxane-2-carboxylate; 1-(4-{2-[(2,6-Dimethylphenyl)amino]-2-oxoethyl}-1-piperazinyl)-3-(2-methoxyphenoxy)-2-propanyl methyl 2,3,4-tri-O-isobutyryl-β-D-glucopyranosiduronate; 1-Piperazineacetamide, N-(2,6-dimethylphenyl)-4-[3-(2-methoxyphenoxy)-2-[[6-methyl-2,3,4-tris-O-(2-methyl-1-oxopropyl)-β-D-glucopyranuronosyl]oxy]propyl]-. Molecular formula: C43H61N3O13. Mole weight: 827.95.
T 98475
T 98475 is a potent, orally active and non-peptide gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist (IC50 = 0.2, 4.0 and 60 nM for human, monkey and rat GnRH receptors, respectively). T 98475 inhibits LH release in vitro (IC50 = 100 nM) and reduces plasma LH concentration in castrated male cynomolgus monkeys. Synonyms: Thieno[2,3-b]pyridine-5-carboxylic acid, 7-[(2,6-difluorophenyl)methyl]-4,7-dihydro-2-[4-[(2-methyl-1-oxopropyl)amino]phenyl]-3-[[methyl(phenylmethyl)amino]methyl]-4-oxo-, 1-methylethyl ester; 1-Methylethyl 7-[(2,6-difluorophenyl)methyl]-4,7-dihydro-2-[4-[(2-methyl-1-oxopropyl)amino]phenyl]-3-[[methyl(phenylmethyl)amino]methyl]-4-oxothieno[2,3-b]pyridine-5-carboxylate; Isopropyl 3-((benzyl(methyl)amino)methyl)-7-((2,6-difluorophenyl)methyl)-2-(4-(2-methylpropanoylamino)phenyl)-4-oxo-thieno(2,3-b)pyridine-5-carboxylate. Grades: ≥98% by HPLC. CAS No. 199119-18-1. Molecular formula: C37H37F2N3O4S. Mole weight: 657.77.
Tenovin-2
Tenovin-2, a diminutive compound inhibitor, offers promise as a therapeutic agent for a range of malignancies, including but not limited to breast cancer and leukemia. Its mechanism of action is attributed to the activation of p53, a multifunctional protein responsible for regulating cellular growth and division. Synonyms: 4-Tert-butyl-N-[[4- (2-methylpropanoylamino) phenyl]carbamothioyl]benzamide; N-[4- ({[ (4-tert-butylbenzoyl) amino]carbothioyl}amino) phenyl]-2-methylpropanamide. CAS No. 666211-30-9. Molecular formula: C22H27N3O2S. Mole weight: 397.537.
YM-170320
YM-170320 is a lipopeptide antibiotic produced by an unidentified fungal strain YL-03706F. It was shown to induce morphological change of colonies in a mutant of Candida tropicalis pK233. It is a novel ergosterol biosynthesis inhibitor. Synonyms: 5-Amino-4-hydroxy-5-oxo-2-[[3-[[2-[(2,6,10,14-tetramethyl-3-hydroxy-1,7-dioxo-8,10-icosadiene-1-yl)amino]propenoyl]amino]-2-methylpropanoyl]amino]pentanoic acid methyl ester. Molecular formula: C37H62N4O9. Mole weight: 706.91.
Zofenopril Calcium Salt
Zofenopril Calcium is an antioxidant and acts as an angiotensin-converting enzyme (ACE) inhibitor. lt is also an inhibitor of PEPT2, the predominant peptide transporter in kidney and choroid plexus. lt is a pro-drug designed to undergo metabolic hydrolysis yielding the active free sulfhydryl compound zofenoprilat. lt promotes the regeneration of peripheral nerve injuries in rat models. lt increases SR calcium cycling and stimulates active calcium uptake into the SR. It was developed by the Bristol Myers Squibb Company. Uses: Zofenopril calcium promotes the regeneration of peripheral nerve injuries in rat models. lt increases sr calcium cycling and stimulates active calcium uptake into the sr. Synonyms: SQ26991; SQ 26991; SQ-26991; (4S)-N-[3-(benzoylsulfanyl)-2(s)-methylpropionyl]-4-(phenylsulfanyl)-l-proline calcium salt;[1(S),4(S)]-1-(3-Mercapto-2-methyl-1-oxopropyl)-4-phenyl-thio-L-proline-S-benzoyl Ester Calcium Salt;[(4S)-(2S)-3-(benzoylthio)-2-methylpro-pionyl-4-(phenylthio)-L-prolinelcalcium;Calcium;(2S,4S)-1-[(2S)-3-benzoylsulfanyl-2-methylpropanoyl]-4-phenylsulfanylpyrrolidine-2-carboxylate. Grades: 95%. CAS No. 81938-43-4. Molecular formula: C44H44CaN2O8S4. Mole weight: 897.17.
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