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D-myo-Inositol 1,2,3-triphosphate is an indispensable biomolecular entity, exhibiting its significance as a paramount signaling molecule. Its essentiality derives from its pivotal participation in the intricate process of intracellular calcium release, thereby facilitating various physiological phenomena encompassing neurotransmission and muscular contraction. Synonyms: Ins(1,2,3)P3. CAS No. 41613-02-9. Molecular formula: C6H15O15P3. Mole weight: 420.10.
D-myo-Inositol-1,2,6-triphosphate sodium salt
D-myo-Inositol-1,2,6-triphosphate sodium salt is an eminent compound assuming the significant function of a secondary messenger molecule, concentrating solely on cellular signal transduction pathways. Exercising crucial control over intracellular calcium levels, this compound ultimately governs a myriad of cellular processes. Synonyms: 1,2,6-IP3. Molecular formula: C6H12O15P3 xNa. Mole weight: 417.07 (free acid basis).
D-myo-Inositol-1,3,4-triphosphate
D-myo-Inositol-1,3,4-triphosphate is a pivotal signaling molecule orchestratingand modulating an array of cellular functions, ranging from neurotransmitter liberation to the orchestration of muscular contracts and extends its impact even towards the delicate domain of immune responses. CAS No. 140385-74-6. Molecular formula: C6H12O15P3. Mole weight: 417.07.
D-myo-Inositol-1,3,4-triphosphate sodium salt
D-myo-Inositol-1,3,4-triphosphate (Ins(1,3,4)-P3) is one of several different inositol oligophosphate isomers implicated in signal transduction. Ins(1,3,4)-P3 acts through the inhibition of Ins(3,4,5,6)-P4 kinase activity to increase the cellular level of Ins(3,4,5,6)-P4 and thus inhibit calcium-activated chloride channels. Synonyms: D-myo-Inositol-1,3,5-triphosphate, sodium salt; 1,3,4-IP3 (sodium salt); 1,3,5-IP3 (sodium salt); HMS3650K09; Ins(1,3,5)P3 (sodium salt); Ins(1,3,4)-P3 (sodium salt); PD020265; D-myo-Inositol-1,3,4-triphosphate sodium salt. Grades: ≥98%. Molecular formula: C6H12Na3O15P3. Mole weight: 486.04.
D-Myo-inositol-1,3,5-triphosphate ammonium salt
D-Myo-inositol-1,3,5-triphosphate ammonium salt is a prominent compound, possessing immense significance as a pivotal cellular messenger in signal transduction pathways. This product finds substantial utility in the realm of studying calcium signaling, cellular metabolism and the regulation of cellular functions. Synonyms: myo-Inositol-1,3,5-tris(dihydrogen phosphate), Ammonium Salt (1:3); (1R,2S,3r,4R,5S,6s)-2,4,6-Trihydroxycyclohexane-1,3,5-triyl tris(dihydrogen phosphate), Triammonia Salt; IP3(1,3,5); (1R,2S,3r,4R,5S,6s)-2,4,6-Trihydroxy-1,3,5-cyclohexanetriyl tris[dihydrogen (phosphate)] triammoniate; 1,2,3,4,5,6-Cyclohexanehexol, 1,3,5-tris(dihydrogen phosphate), triammonium salt, (1α, 2α, 3α, 4β, 5α, 6β)-. Grades: >99%. CAS No. 1246355-67-8. Molecular formula: C6H24N3O15P3. Mole weight: 471.19.
D-myo-Inositol-1,3,5-triphosphate sodium salt
D-myo-Inositol-1,3,5-triphosphate sodium salt is an indispensable biomedical commodity extensively employed in research and pharmaceutical domains, serving as a vital second messenger in diverse cellular processes, thereby promoting intracellular calcium signaling. Molecular formula: C6H12O15P3 xNa. Mole weight: 417.07 (free acid basis).
D-myo-Inositol-1,3,6-triphosphate
D-myo-Inositol-1,3,6-triphosphate is a fundamental bioactive compound extensively utilized in the realm of intracellular calcium pathways, fostering the research of intricate cellular functions encompassing neurotransmitter emancipation, endocrine exudation and even the orchestration of musculature. Molecular formula: C6H15O15P3. Mole weight: 420.10.
D-Myo-inositol-1,4,5-triphosphate ammonium salt
D-Myo-inositol-1,4,5-triphosphate ammonium salt is a highly sought-after compound, manifesting as an instrumental entity in the intricate web of signal transduction pathways by functioning as a second messenger. Its paramount role lies in meticulously orchestrating calcium levels within cellular confines. Synonyms: D-myo-Inositol-1,4,5-tris(dihydrogen phosphate) Triammonium Salt;_x000B_rac-(1R,2R,3S,4R,5R,6S)-3,5,6-Trihydroxycyclohexane-1,2,4-triyl tris(dihydrogen phosphate), Triammonia Salt; (1R,2R,3S,4R,5R,6S)-3,5,6-Trihydroxy-1,2,4-cyclohexanetriyl tris[dihydrogen (phosphate)] triammoniate; IP3(1,4,5). Grades: >99%. CAS No. 345958-55-6. Molecular formula: C6H24N3O15P3. Mole weight: 471.19.
D-myo-Inositol 1,4,5-triphosphate potassium salt
D-myo-Inositol 1,4,5-triphosphate potassium salt is a paramount compound, finding extensive utility in the research of cellular signaling pathways. Serving as an inositol derivative, this product assumes the onerous responsibility of an efficacious second messenger for a myriad of intracellular phenomena. Unleashing its potential to mobilize calcium from intraorganic repositories, it assumes a critical function in the realm of neurotransmission investigation, cellular expansion and intricate proliferation exploration. Synonyms: d-Myo-inositol-1,4,5-trisphosphate tripotassium salt; D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt; hexapotassium; [(1R,2S,3R,4R,5S,6R)-2,3,5-trihydroxy-4,6-diphosphonatooxycyclohexyl] phosphate; Ins(1,4,5)-P3 hexapotassium salt; Ins(1,4,5)-P3 hexapotassium salt; 1,4,5-IP3 hexapotassium salt; 1,4,5-Ip3,hexapotassium salt; AKOS024456627; D-Myo-inositol 1,4,5-trisphosphate,hexapotassium salt; D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt; potassium (1R,2R,3S,4R,5R,6S)-3,5,6-trihydroxycyclohexane-1,2,4-triyl triphosphate. CAS No. 103476-24-0. Molecular formula: C6H9K6O15P3. Mole weight: 648.64.
D-myo-Inositol-1,4,5-triphosphate potassium salt
D-myo-Inositol-1,4,5-triphosphate (Ins(1,4,5)P3) is a second messenger produced in cells by phospholipase C (PLC) mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate. It binds to one of several Ins(1,4,5)P3 receptors, each containing a calcium channel domain. Binding of Ins(1,4,5)P3 to the receptor results in opening of the calcium channels and an increase in intracellular calcium. Synonyms: D-MYO-INOSITOL 1,4,5-TRIPHOSPHATE TRIPOTASSIUM SALT; tripotassium; [ (1R, 2S, 3R, 4R, 5S, 6R)-2, 3, 5-trihydroxy-4, 6-bis[[hydroxy (oxido)phosphoryl]oxy]cyclohexyl] hydrogen phosphate; D-Myo-inositol-1,2,5-tris(dihydrogen phosphate), tripotassium salt; PD020902; D-myo-Inositol 1,4,5-triphosphate tripotassium salt, >=95% (HPLC). Grades: ≥98%. CAS No. 141611-11-2. Molecular formula: C6H12O15P3·3K. Mole weight: 534.4.
D-myo-Inositol 1,4,5-triphosphate sodium salt
D-myo-Inositol 1,4,5-triphosphate sodium salt is an imperative secondary messenger with pivotal involvement in numerous cell signaling pathways, this product exerts regulation over intracellular calcium levels. Its extensive research has revealed its significant contribution towards studying disorders associated with calcium imbalance, including neurodegenerative diseases, diabetes and cancer. CAS No. 27121-73-9. Molecular formula: C6H9Na6O15P3. Mole weight: 551.99.
D-myo-Inositol-1,4,5-triphosphate sodium salt
D-myo-Inositol-1,4,5-triphosphate (Ins(1,4,5)P3) is a second messenger produced in cells by phospholipase C mediated hydrolysis of phosphatidyl inositol-4,5-biphosphate. Binding of Ins(1,4,5)P3 to the receptor results in opening of the calcium channels and an increase in intracellular calcium. Grades: ≥98%. CAS No. 141611-10-1. Molecular formula: C6H12O15P3·3Na. Mole weight: 486.
D-myo-Inositol 1,4,5-triphosphate tripotassium salt
D-myo-Inositol 1,4,5-triphosphate tripotassium salt. Uses: For analytical and research use. Group: Impurity standards. CAS No. 141611-11-2. Molecular Formula: C6H12K3O15P3. Mole Weight: 534.36. Catalog: APB141611112.
D-myo-Inositol 1,4,6-triphosphate sodium salt
D-myo-Inositol 1,4,6-triphosphate sodium salt is an extensively refined chemical compound employed in the biomedical sector assuming the role of an intracellular messenger, orchestrating intricate cellular processes, namely, cell growth and calcium signaling. It manifests pivotal significance in the research of maladies associated with the dysregulation of inositol phosphate pathways, encompassing select cancers, neurodegenerative disorders and metabolic irregularities. Synonyms: Ins(1,4,6)-P3 (sodium salt); 1,4,6-IP3 (sodium salt). CAS No. 157380-18-2. Molecular formula: C6H12O15P3 xNa. Mole weight: 417.07 (free acid basis).
D-myo-Inositol-1,5,6-triphosphate sodium salt
D-myo-Inositol-1,5,6-triphosphate sodium salt is a fundamental compound prominently employed sector assuming an indispensable character within cellular signal transduction pathways, orchestrating sundry physiological processes. This prodigious entity operates as a secondary courier is adroitly overseeing calcium levels and intricately modulating multifarious cellular functionalities. Synonyms: 1,5,6-IP3 sodium salt; Ins(1,5,6)-P3 sodium salt. CAS No. 120965-76-6. Molecular formula: C6H12O15P3 xNa. Mole weight: 417.07 (free acid basis).
D-myo-Inositol-2,3,5-triphosphate ammonium salt is a member of the inositol phosphate (InsP) family of second messengers which play an important role in the transmission of cellular signals. Ins(2,3,5)P3 ammonium salt is 500-fold less potent than Ins(1,4,5)-P3 at initiating Ca2+ release when injected into Xenopus oocytes. Synonyms: Ins(2,3,5)P3 ammonium salt; 2,3,5-IP3 ammonium salt; D-myo-inositol-2,3,5-tris(dihydrogen phosphate), triammonium salt. Grades: ≥98%. Molecular formula: C6H12O15P3·3NH4. Mole weight: 522.3.
D-myo-Inositol-2,4,5-triphosphate sodium salt
D-myo-Inositol-2,4,5-triphosphate sodium salt is a second messenger produced in cells by phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositol-4,5-biphosphate. Ins(2,4,5)P3 acts as a partial agonist at rat hepatic IP3 receptors, exhibiting 65% of the maximal Ca2+ response obtained with Ins(1,4,5)P3. Synonyms: Ins(2,4,5)P3 sodium salt; 2,4,5-IP3 sodium salt; D-myo-inositol-2,4,5-tris(hydrogen phosphate), trisodium salt. Grades: ≥98%. Molecular formula: C6H12O15P3·3Na. Mole weight: 486.
D-myo-Inositol-2,5,6-triphosphate sodium salt
Ins(2,5,6)P3 is a less potent inducer of calcium release from permeabilized rat basophilic leukemia cells with an EC50 value of 110 μM compared to Ins(1,4,5)P3, which has an EC50 value of 0.17 μM. Synonyms: Ins(2,5,6)P3 sodium salt; 2,5,6-IP3 sodium salt; D-myo-inositol-2,5,6-tris(dihydrogen phosphate), trisodium salt. Grades: ≥98%. Molecular formula: C6H12O15P3·3Na. Mole weight: 486.
D-myo-Inositol-3,4,5-triphosphate
D-myo-Inositol-3,4,5-triphosphate is an indispensable molecule in the biomedical field, serving as a pivotal second messenger within intracellular signaling pathways, imposing control over calcium homeostasand intricate cellular mechanisms. Its significance lies in orchestrating critical processes, encompassing cellular proliferation, specialization and programmed cell death. The utilization of D-myo-Inositol-3,4,5-triphosphate prevails prominently in research endeavors and pharmaceutical advancements, with a primary focus on comprehending signal transduction, unraveling the complexities of neoplastic disorders and exploring promising therapeutic modalities. Synonyms: Ins(3,4,5)-P3; 3,4,5-IP4. Molecular formula: C6H12O15P3. Mole weight: 417.07.
D-myo-Inositol-3,4,5-triphosphate sodium salt
D-myo-Inositol-3,4,5-triphosphate (Ins(3,4,5)-P3) is a structural analog of Ins(1,4,5)-P3 and also a member of the inositol phosphate (InsP) cell signaling family of molecules. D-myo Ins(3,4,5)-P3 is 200-fold less potent than D-myo Ins(1,4,5)-P3 at initiating Ca++ release when injected into Xenopus oocytes. Ins(3,4,5)-P3 binds to Type 1, 2, and 3 subtypes of the rat recombinant IP3 receptor with Ki values of 3-11 μM. Synonyms: Ins(3,4,5)-P3; 3,4,5-IP4; D-myo-inositol-3,4,5-tris(hydrogen phosphate), trisodium salt. Grades: ≥98%. Molecular formula: C6H12O15P3·3Na. Mole weight: 486.
Atrinositol
Atrinositol is an analog of Ins(1,4,5)P3. It improves energy homeostasis in a mouse model of pancreatic cancer. Synonyms: Inositol 1,2,6-trisphosphate; Ins(1,2,6)P3; D-myo-Inositol 1,2,6-tris(dihydrogen phosphate); D-myo-Inositol-1,2,6-triphosphate; trinositol. Grades: >95%. CAS No. 28841-62-5. Molecular formula: C6H15O15P3. Mole weight: 420.10.
diphosphoinositol-pentakisphosphate kinase
This enzyme is activated by osmotic shock. Ins(1,3,4,5,6)P5, 1D-myo-inositol diphosphate tetrakisphosphate and 1D-myo-inositol bisdiphosphate triphosphate are not substrates. Group: Enzymes. Synonyms: PP-IP5 kinase; diphosphoinositol pentakisphosphate kinase; ATP:5-diphospho-1D-myo-inositol-pentakisphosphate phosphotransferase; PP-InsP5 kinase; PPIP5K; PPIP5K1; PPIP5K2; VIP1; VIP2. Enzyme Commission Number: EC 2.7.4.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3206; diphosphoinositol-pentakisphosphate kinase; EC 2.7.4.24; PP-IP5 kinase; diphosphoinositol pentakisphosphate kinase; ATP:5-diphospho-1D-myo-inositol-pentakisphosphate phosphotransferase; PP-InsP5 kinase; PPIP5K; PPIP5K1; PPIP5K2; VIP1; VIP2. Cat No: EXWM-3206.
D-myo-Inositol-1,3,4,5-tetraphosphate sodium salt
D-myo-Inositol-1,3,4,5-tetraphosphate sodium salt is formed by the phosphorylation of Ins(1,4,5)P4 by inositol 1,4,5-triphosphate 3-kinase. Ins(1,3,4,5)P4 acts in conjunction with IP3 to mobilize intracellular calcium. Synonyms: D-myo-Inositol-1,3,4,5-tetrakis(phosphate) octasodium salt; Ins(1,3,4,5)P4 sodium salt. CAS No. 210488-61-2. Molecular formula: C6H8Na8O18P4. Mole weight: 675.93.
D-Myo-inositol 1,4,5-trisphosphate,hexapotassium salt
Heterocyclic Organic Compound. Alternative Names: 1,4,5-IP3, HEXAPOTASSIUM SALT;IP3;IP3 6K;INS(1,4,5)P3 HEXAPOTASSIUM SALT;INS(1,4,5)P3 6K;INS(1,4,5)IP3 (POTASSIUM SALT);INS(1,4,5)P3;D-MYO-INOSITOL 1,4,5-TRIPHOSPHATE HEXAPOTASSIUM SALT. CAS No. 103476-24-0. Molecular formula: C6H9K6O15P3. Mole weight: 648.64. Appearance: White to off-white solid. Purity: ≥98%. Catalog: ACM103476240.
D-Myo-inositol 1,4,5-trisphosphate triammonium salt
One mammalian isoform is known. This enzyme is distinguished from the family of enzymes classified under EC 3.1.3.36, phosphoinositide 5-phosphatase, by its inability to dephosphorylate inositol lipids. Group: Enzymes. Synonyms: type I inositol-polyphosphate phosphatase; inositol trisphosphate phosphomonoesterase; InsP3/Ins(1,3,4,5)P4 5-phosphatase; inosine triphosphatase; D-myo-inositol 1,4,5-triphosphate 5-. Enzyme Commission Number: EC 3.1.3.56. CAS No. 106283-14-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3661; inositol-polyphosphate 5-phosphatase; EC 3.1.3.56; 106283-14-1; type I inositol-polyphosphate phosphatase; inositol trisphosphate phosphomonoesterase; InsP3/Ins(1,3,4,5)P4 5-phosphatase; inosine triphosphatase; D-myo-inositol 1,4,5-triphosphate 5-phosphatase; D-myo-inositol 1,4,5-trisphosphate 5-phosphatase; L-myo-inositol 1,4,5-trisphosphate-monoesterase; inositol phosphate 5-phosphomonoesterase; inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase; Ins(1,4,5)P3 5-phosphatase; D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase; inositol 1,4,5-trisphosphate phosphatase; inositol polyphosphate-5-phosphatase; myo-inositol-1,4,5-trisphosphate 5-phosphatase; inositol-1,4,5-trisphosphate 5-phosphatase. Cat No: EXWM-3661.
IP3(1,3,4) ammonium salt
IP3(1,3,4) ammonium salt is a chemical which occurs naturally in carbachol-stimulated rat parotid glands. Ins(1,3,4)P3 inhibits Ins(3,4,5,6)P4 1-kinase which regulates Ins(3,4,5,6)P4 levels. Synonyms: D-Myo-inositol-1,3,4-triphosphate (ammonium salt); rac-(1R,2R,3R,4R,5S,6S)-3,5,6-Trihydroxycyclohexane-1,2,4-triyl tris(dihydrogen phosphate), Triammonia Salt. Grades: >97%. CAS No. 1246355-66-7. Molecular formula: C6H24N3O15P3. Mole weight: 471.19.
myo-Inositol trispyrophosphate (ITPP) hexasodium is a salt form of inositoltriphosphate (ITPP). myo-Inositol trispyrophosphate (ITPP) hexasodium is a membrane-permeant hemoglobin allosteric regulator. myo-Inositol trispyrophosphate (ITPP) hexasodium enhances the oxygen release capacity of red blood cells by reducing the affinity of hemoglobin to oxygen. myo-Inositol trispyrophosphate (ITPP) hexasodium can be used in the study of cardiovascular disease and cancer [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ITPP hexasodium. CAS No. 23103-35-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141510.
phosphoinositide 5-phosphatase
These enzymes can also remove the 5-phosphate from Ins(1,4,5)P3 and/or Ins(1,3,4,5)P4. They are a diverse family of enzymes, with differing abilities to catalyse two or more of the four reactions listed. They are thought to use inositol lipids rather than inositol phosphates as substrates in vivo. All of them can use either or both of PtdIns(4,5)P2 and PtdIns(3,4,5)P3 as substrates; this is the main property that distinguishes them from EC 3.1.3.56, inositol-polyphosphate 5-phosphatase. Group: Enzymes. Synonyms: type II inositol polyphosphate 5-phosphatase; triphosp. Enzyme Commission Number: EC 3.1.3.36. CAS No. 9036-1-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3639; phosphoinositide 5-phosphatase; EC 3.1.3.36; 9036-01-5; type II inositol polyphosphate 5-phosphatase; triphosphoinositide phosphatase; IP3 phosphatase; PtdIns(4,5)P2 phosphatase; triphosphoinositide phosphomonoesterase; diphosphoinositide phosphatase; inositol 1,4,5-triphosphate 5-phosphomonoesterase; inositoltriphosphate 5-phosphomonoesterase; phosphatidylinositol-bisphosphatase; phosphatidyl-myo-inositol-4,5-bisphosphate phosphatase; phosphatidylinositol 4,5-bisphosphate phosphatase; polyphosphoinositol lipid 5-phosphatase; phosphatidyl-inositol-bisphosphate phosphatase. Cat No: EXWM-3639.
These enzymes form some of the cyclic phosphate Ins(cyclic1,2)P(4,5)P2 as well as Ins(1,4,5)P3. They show activity towards phosphatidylinositol, i.e., the activity of EC 4.6.1.13, phosphatidylinositol diacylglycerol-lyase, in vitro at high [Ca2+]. Four β-isoforms regulated by G-proteins, two γ-forms regulated by tyrosine kinases, four Δ-forms regulated at least in part by calcium and an ε-form, probably regulated by the oncogene ras, have been found. Group: Enzymes. Synonyms: triphosphoinositide phosphodiesterase; phosphoinositidase C; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase; monophosphatidylinositol phosphodiesterase; phosphatidylinositol phospholipase C; PI-PLC; 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase. Enzyme Commission Number: EC 3.1.4.11. CAS No. 63551-76-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3711; phosphoinositide phospholipase C; EC 3.1.4.11; 63551-76-8; triphosphoinositide phosphodiesterase; phosphoinositidase C; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase; monophosphatidylinositol phosphodiesterase; phosphatidylinositol phospholipase C; PI-PLC; 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase. Cat No: EXWM-3711.
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