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Reagent for preparation of active esters of amino acids. Used in the carbodiimide method for improved amidations and peptide couplings. Group: Biochemicals. Alternative Names: HOSu; 1-Hydroxy-2,5-pyrrolidinedione; N-Hydroxy-2,5-dioxopyrrolidine; 1-Hydroxysuccinimide; NSC 74335; NHS. Grades: Highly Purified. CAS No. 6066-82-6. Pack Sizes: 25g, 100g, 250g, 1Kg, 5Kg. Molecular Formula: C?H?NO?, Molecular Weight: 115.1. US Biological Life Sciences.
A highly amine reactive spin-label. Group: Biochemicals. Alternative Names: OXYL-1-NHS. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
The hydrophilic polymer contains polar or charged functional groups, making it soluble in water. Uses: Pnipam-based smart surfaces for cell sheet tissue engineering novel polymer for development of thermosensitive coated micro/nano materialincluding thermoresponsive polymeric drug delivery systems. the nhs ester functional group can be used to conjugate a variety of biomolecules such as enzymes to the polymer chain. Group: Hydrophilic polymers. Alternative Names: functionalized polyNIPAM, functionalized polyacrylamide, Polyacrylamide, NIPAM polymer, PNIPAM-NHS, polyNIPAM. Pack Sizes: Packaging 1, 5 g in glass bottle. Molecular formula: average Mn 2,000. Mole weight: (C6H11NO)n SCH2CH2COO(C4H4NO2).
6-Carboxyfluorescein N-succinimidyl ester is the amine-reactive succinimidyl ester carboxyfluorescein that is used in the labeling of nucleotides and nucleic acids. Synonyms: FAM NHS ester, 6-isomer;OSu-FAM; 6-FAM, SE; 6-FAM SE; 6-Carboxyfluorescein-NHS; 6-Carboxyfluorescein N-hydroxysuccinimide ester; (2,5-dioxopyrrolidin-1-yl) 3',6'-dihydroxy-1-oxospiro[2-benzofuran-3,9'-xanthene]-5-carboxylate. Grades: NMR 1H, HPLC-MS (95%). CAS No. 92557-81-8. Molecular formula: C25H15NO9. Mole weight: 473.393.
Acridinium C2 N-hydroxysuccinimide ester
Acridinium C2 N-hydroxysuccinimide ester. Group: Biochemicals. Alternative Names: 4-(2-Succinimidyl-oxycarbonylethyl)-phenyl-10-acridinium-9-carboxylate triflurormethyl sulfonate; Acridinium C2 NHS ester. Grades: Highly Purified. CAS No. 177332-37-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C29H23F3N2O9S. US Biological Life Sciences.
Worldwide
AMT-NHS
AMT-NHS is an RNA-protein crosslinker that can be used to capture different RNA-protein interactions in cells. AMT-NHS consists of a psoralen derivative and an N-hydroxysuccinimide ester group that reacts with the RNA bases and primary amines of proteins, respectively. AMT-NHS can penetrate living yeast cells and cross-link Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different cross-linking patterns and targets both single-stranded and double-stranded regions of RNA. Synonyms: 2,5-dioxopyrrolidin-1-yl 3-(((2,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-3-yl)methyl)thio)propanoate. Molecular formula: C22H21NO7S. Mole weight: 443.47.
Atto 590 nhs ester
ATTO 590 is a novel fluorescent label belonging to the class of Rhodamine dyes. The dye is designed for application in the area of life science, e.g. labeling of DNA, RNA or proteins. The ATTO dyes are a series of fluorescent dyes that provide all the crucial properties required for modern fluorescent technologies, such as fluorescence microscopy, flow-cytometry, fluorescence in situ hybridization (FISH), receptor binding assays or enzyme assays. The dye is highly suitable for single-molecule detection applications and high-resolution microscopy. The NHS-esters are used in common conjugation protocols.ATTO 590 is a novel fluorescent label belonging to the class of Rhodamine dyes, which has an absorption maximum of 594 nm and an emission maximum of 624 nm. ATTO 590-N-hydroxysuccinimide (NHS) is membrane permeable. Uses: Molar absorption 120,000 1/m cm, abs: 593 nm, em: 620 nm, qy=0.93, tfl 4.0 ns (unpublished data)atto 590 nhs ester may be suitable for use in site-specific labeling of human embryonic kidney (hek293t) cell lysates for western blotting, fluorescence, and widefield microscopy studies. Synonyms: 2-(6, 20-diethyl-7, 7, 9, 17, 19, 19-hexamethyl-2-oxa-20-aza-6-azoniapentacyclo[12.8.0.03, 12.05, 10.016, 21; docosa-1(14),3,5,8,10,12,15,17,21-nonaen-13-yl)-4-(2,5-dioxopyrrolidin-1-yl)oxycarbonylbenzoic acid;perchlorate; 6-(2-Carboxy-5-{[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}phenyl)-1,11-diethyl-2,2,4,8,10,10-hexamethyl-10,11-dihydro-2H-pyrano[3,2-g:5,6-g']diquinolin-1-ium perchlorate. Grades: ≥60% (coupling to amines). CAS No. 670269-33-7. Molecular formula: C41H42ClN3O11. Mole weight: 788.24.
Biotin NHS
Biotin NHS is an amino reactive biotin reagent used in the preparation of biotinylated surfaces or polypeptides. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Biotin N-hydroxysuccinimide ester; NHS-Biotin. CAS No. 35013-72-0. Pack Sizes: 100 mg; 200 mg. Product ID: HY-D0802.
Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and redu. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: Biotin-PEG, Poly(ethylene glycol) (N-hydroxysuccinimide acetic acid) ether biotin, protected valeric acid, biotin carboxylic acid PEG, NHS - protected acid PEG, Biotin polyoxyethylene maleimide, Biotin-PEG maleimide, Biotinylated PEG. Pack Sizes: Packaging 100 mg in glass insert. Molecular formula: PEG ave
SPDP
SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups. Uses: A heterobifunctional cross-linker. Synonyms: N-Succinimidyl 3-(2-Pyridyldithio)Propionate; UNII-2OHG8V08NL; SPDP NHS Ester; 3-(2-Pyridyldithio)Propionic Acid N-Hydroxysuccinimide Ester. Grades: ≥ 97% (HPLC). CAS No. 68181-17-9. Molecular formula: C12H12N2O4S2. Mole weight: 312.37.
SPDP Crosslinker
SPDP contains a dithiopyridyl group which is reactive towards cysteines (-SH groups) and an NHS group, which is useful when targeting primary amines (-NH2 groups). SPDP releases a byproduct, pyridine-2-thione after reacting with free sulfhydryl groups. By measuring the release of this byproduct at 343nm, the reaction can be easily followed. Contains a disulfide linkage in its spacer arm with a length of 6.8. Group: Biochemicals. Alternative Names: N-succinimidyl-3- (2-pyridyldithio) propionate; 3- (2-Pyridyldithio) propionic acid N-hydroxysuccinimide ester; 3- (2-Pyridyldithio) propionic acid NHS ester. Grades: Highly Purified. CAS No. 68181-17-9. Pack Sizes: 50mg, 250mg. US Biological Life Sciences.
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively. Synonyms: Sulfo-SMCC; Sodium 1-((4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarbonyl)oxy)-2,5-dioxopyrrolidine-3-sulfonate. Grades: >98.0%. CAS No. 92921-24-9. Molecular formula: C16H17N2NaO9S. Mole weight: 436.37.
Sulfo-SMCC sodium
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 92921-24-9. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-D0975.
Thiazole Orange NHS Ester
Thiazole Orange NHS Ester is a fluorescent labeling reagent used in biomedical research to selectively label DNA and RNA in living cells. It has also been used to monitor the function of lysosomes and to identify amyloid-beta plaques in Alzheimer's disease. Synonyms: N-(5-carboxypentyl)-2-[(1,4-dihydro-1-methylquinolin-4-ylidene)methyl]benzothiazol-3-ium chloride N-hydroxysuccinimide ester. Molecular formula: C28H28ClN3O4S. Mole weight: 538.06.
Alkyne-NHS Ester, a vital chemical compound, is increasingly employed in bioconjugation reactions to append alkyne groups to proteins, peptides, or other molecules. This action enables the detection or labeling of biomolecules with a plethora of techniques, including fluorescent microscopy or mass spectrometry. Alkyne-NHS Ester is particularly valuable in drug discovery and development research as well as diagnostic applications for infectious diseases, thereby reinforcing its significance in the world of science. Synonyms: 3-propargyloxypropanoic acid N-hydroxysuccinimidyl ester. Molecular formula: C10H11NO5. Mole weight: 225.20.
Desthiobiotin N-Hydroxysuccinimidyl Ester
Desthiobiotin N-Hydroxysuccinimidyl Ester is a highly valued reagent commonly employed in the biomedicine sector for the purpose of labeling nucleic acids and proteins through primary amine groups. This reagent finds wide usage in the proteomics space primarily for the tasks of detection and purification of proteins. Synonyms: Desthiobiotin NHS Ester. Grades: 95%. CAS No. 80750-24-9. Molecular formula: C14H21N3O5. Mole weight: 311.33.
TSTU is able to converse carboxylic acid to the corresponding N-hydroxysuccinimidyl (NHS) ester, and is utilized as coupling reagent in peptide chemistry [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 105832-38-0. Pack Sizes: 25 g. Product ID: HY-W011412.
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