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2-Octenoic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (2E)-2-Octenoic acid;2-OCTENOIC ACID (TRANS-);2-OCTENOIC ACID;FEMA NUMBER 3957;T2 OCTENOIC ACID;RARECHEM AL BK 0164;TRANS-2-OCTENOIC ACID;2-Octenoic acid oct-2-enoic acid. Product Category: Heterocyclic Organic Compound. CAS No. 1470-50-4. Molecular formula: C8H14O2. Mole weight: 142.2. Purity: 0.97. Density: 0.944 g/mL at 25 °C(lit.). Product ID: ACM1470504. Alfa Chemistry ISO 9001:2015 Certified.
2-Octenoic acid,ethylester
2-Octenoic acid,ethylester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Octenoic acid, ethyl ester;2-Octenoicacid,ethylester;Ethyl (2E)-2-octenoate;ETHYL T2 OCTENOATE;ETHYL TRANS-2-OCTENOATE;FEMA 3643;ETHYL 2-OCTENOATE;RARECHEM AL BI 0153. Product Category: Heterocyclic Organic Compound. CAS No. 2351-90-8. Molecular formula: C10H18O2. Mole weight: 170.25. Purity: 0.96. IUPACName: ethyl (E)-oct-2-enoate. Canonical SMILES: CCCCCC=CC(=O)OCC. Density: 0.892g/cm³. ECNumber: 230-913-1. Product ID: ACM2351908. Alfa Chemistry ISO 9001:2015 Certified.
7-METHYL-7-OCTENOIC ACID
7-METHYL-7-OCTENOIC ACID. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-METHYL-7-OCTENOIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 5212-71-5. Molecular formula: C9H16O2. Mole weight: 156.22. Purity: 0.96. IUPACName: 2-chloro-2-fluoro-2-(2,3,4-trifluoro-5,6-diphenylphenyl)acetamide. Canonical SMILES: CC(=C)CCCCCC(=O)O. Density: 1.386g/cm³. Product ID: ACM5212715. Alfa Chemistry ISO 9001:2015 Certified.
7-Octenoic acid
7-Octenoic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CTK0H3975; ACMC-20alws; I14-38537; DTXSID30337674; OZYYQTRHHXLTKX-UHFFFAOYSA-N; 7-Octenoic acid, 97%; MFCD02258724 (97%); LMFA01030576; AC1LBX4Y; UMY8YV4JPR. Product Category: Alkenes. CAS No. 18719-24-9. Molecular formula: C8H14O2. Mole weight: 142.198g/mol. IUPACName: oct-7-enoic acid. Canonical SMILES: C=CCCCCCC(=O)O. Product ID: ACM18719249. Alfa Chemistry ISO 9001:2015 Certified.
(E)-3,7-Dimethyl-2-octenoic Acid Ethyl Ester
(E)-3,7-Dimethyl-2-octenoic Acid Ethyl Ester. Group: Biochemicals. Alternative Names: Ethyl (E)-3,7-Dimethyl-2-octenoate. Grades: Highly Purified. CAS No. 59060-59-2. Pack Sizes: 1g. Molecular Formula: C12H22O2, Molecular Weight: 198.3. US Biological Life Sciences.
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trans-2-Octenoic acid ethyl ester
trans-2-Octenoic acid ethyl ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 7367-82-0. Pack Sizes: 5g, 10g, 25g, 50g. Molecular Formula: C10H18O2. US Biological Life Sciences.
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Alternaric acid
It is produced by the strain of Alternaria solani. The main antifungal activity was 0.1-1.0 ?/mL, which inhibited the spore germination of Plomonas aeruginosa, Porphyra porphyra and Black grapevine panicle. Synonyms: D-Arabinonic acid,4,5-dideoxy-2-C-((1E)-7-((6R)-5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-4-methylene-7-oxo-1-heptenyl)-4-ethyl; 3-Nonenoic acid,9-(5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)-2-hydroxy-2-(1-hydroxy-2-methylbutyl)-6-methylene-9-oxo-,(6R-(3(2S*(1R*,2S*),3E),6R*)); 3-Octenoic acid,2-hydroxy-2-(1-hydroxy-2-methylbutyl)-6-methylene-8-[(tetrahydro-6-methyl-2,4-dioxopyran-3-yl)carbonyl]-(8CI); Alternaric acid (6CI,7CI); D-Arabinonic acid,4,5-dideoxy-2-C-[(1E)-7-[(6R)-5,6-dihydro-4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl]-4-methylene-7-oxo-1-heptenyl]-4-ethyl-(9CI). Grades: 98%. CAS No. 10088-62-7. Molecular formula: C21H30O8. Mole weight: 410.46.
A non-immunosuppressive analog. Group: Biochemicals. Alternative Names: 6-[(2S,3R,4R,6E)-3-(Acetyloxy)-4-methyl-2-(methylamino)-6-octenoic acid] Cyclosporin A; B 3-243; O-Acetyl-C91-cyclosporin A; O-Acetylcyclosporin A; SDZ 33-243. Grades: Highly Purified. CAS No. 83602-41-9. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Cyclosporin A-d4 Acetate (Major)
A non-immunosuppressive analog. Group: Biochemicals. Alternative Names: 6-[(2S,3R,4R,6E)-3-(Acetyloxy)-4-methyl-2-(methylamino)-6-octenoic-d4 acid] Cyclosporin A; B 3-243-d4; O-Acetyl-C91-cyclosporin A-d4; O-Acetylcyclosporin A-d4; SDZ 33-243-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cyclosporin AM 1
A cyclosporine metabolite specifically inhibits growth of renal cells in culture. Group: Biochemicals. Alternative Names: 6-[(2S,3R,4R,6E)-3,8-Dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin A; Cyclosporin A Metabolite 17; Cyclosporin Metabolite 17; M 17; OL 17. Grades: Highly Purified. CAS No. 89270-28-0. Pack Sizes: 1mg. US Biological Life Sciences.
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Cyclosporine metabolite M17
Cyclosporine metabolite M17 is a metabolite of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Uses: A cyclosporine metabolite specifically inhibits growth of renal cells in culture. Synonyms: Cyclosporin AM 1; 6-[(2S,3R,4R,6E)-3,8-Dihydroxy-4-methyl-2-(methylamino)-6-octenoic acid]cyclosporin A; Cyclosporin A Metabolite M17; Cyclosporin metabolite AM1; OL-17; 1,4,7,10,13,16,19,22,25,28,31-Undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, 33-[(1R,2R,4E)-1,6-dihydroxy-2-methyl-4-hexen-1-yl]-30-ethyl-1,4,7,10,12,15,19,25,28-nonamethyl-3,21-bis(1-methylethyl)-6,9,18,24-tetrakis(2-methylpropyl)-, (3S, 6S, 9S, 12R, 15S, 18S, 21S, 24S, 30S, 33S)-. Grades: ≥90% by HPLC. CAS No. 89270-28-0. Molecular formula: C62H111N11O13. Mole weight: 1218.61.
Cyclosporin L Related Compound 3
Cyclosporin L Related Compound 3 is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (E)-(2R,3S,4R)-2-Amino-3-hydroxy-4-methyl-oct-6-enoic acid; (2R,3S,4R,6E)-2-amino-3-hydroxy-4-methyl-6-octenoic acid; 2-Amino-4-[(2E)-2-buten-1-yl]-2,4,5-trideoxy-L-arabinonic acid; L-Arabinonic acid, 2-amino-4-[(2E)-2-buten-1-yl]-2,4,5-trideoxy-. Grades: ≥90% by HPLC. CAS No. 174292-85-4. Molecular formula: C9H17NO3. Mole weight: 187.24.
(E)-(5R,7R)-8-Benzyloxy-7-hydroxy-5-methyl-5-vinyl-oct-2-enoic acid ethyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 130675-12-6, ACMC-20mtqu, AGN-PC-001YJG, CTK8G7846, (E)-(5R,7R)-8-BENZYLOXY-7-HYDROXY-5-METHYL-5-VINYL-OCT-2-ENOIC ACID ETHYL ESTER, 2-Octenoic acid,5-ethenyl-7-hydroxy-5-methyl-8-(phenylmethoxy)-, ethyl ester, [R-[R*,R*-(E)]]-(9CI), ethyl (E,5R,7R)-5-ethenyl-7-hydroxy-5-methyl-8-phenylmethoxyoct-2-enoate. Product Category: Heterocyclic Organic Compound. CAS No. 130675-12-6. Molecular formula: C20H28O4. Mole weight: 332.433920 [g/mol]. Purity: 0.96. IUPACName: ethyl 5-ethenyl-7-hydroxy-5-methyl-8-phenylmethoxyoct-2-enoate. Canonical SMILES: CCOC(=O)C=CCC(C)(CC(COCC1=CC=CC=C1)O)C=C. Product ID: ACM130675126. Alfa Chemistry ISO 9001:2015 Certified.
Valspodar
Valspoda, an analog of cyclosporine A, induces caspase-mediated apoptosis. It inhibits multidrug-resistant efflux pump P-glycoprotein, thereby restoring retention and activity of some drugs in some drug-resistant tumor cells. Valspodar has been used in trials studying the treatment of Cancer, Sarcoma, Leukemia, Lymphoma, and Breast Cancer, among others. Synonyms: 6-[(2S,4R,6E)-4-Methyl-2-(methylamino)-3-oxo-6-octenoic Acid]-7-L-valine-cyclosporin A; 6-[[R-(E)]-6,7-Didehydro-N,4-dimethyl-3-oxo-L-2-aminooctanoic acid]-7-L-valinecyclosporin A; 6-[(2S,4R,6E)-4-Methyl-2-(methylamino)-3-oxo-6-octenoic Acid]cyclosporin D; Amdray; PSC 833; SDZ-PSC 833; Valpodar; Cyclo(((2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoyl)-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl). Grades: ≥95%. CAS No. 121584-18-7. Molecular formula: C63H111N11O12. Mole weight: 1214.62.
Valspodar
Valspodar. Group: Biochemicals. Alternative Names: 6-[(2S,4R,6E)-4-Methyl-2-(methylamino)-3-oxo-6-octenoic acid]-7-L-valine-cyclosporin A; 6-[[R-(E)]-6,7-Didehydro-N,4-dimethyl-3-oxo-L-2-aminooctanoic acid]-7-L-valinecyclosporin A; 6-[(2S,4R,6E)-4-Methyl-2-(methylamino)-3-oxo-6-octenoic acid]ccyclosporin D. Grades: Highly Purified. CAS No. 121584-18-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C63H111N11O12. US Biological Life Sciences.
Worldwide
Valspodar.
Antineoplastic adjunct (chemosensitizer). Group: Biochemicals. Alternative Names: 6-[(2S,4R,6E)-4-Methyl-2-(methylamino)-3-oxo-6-octenoic Acid]-7-L-valine-cyclosporin A; 6-[[R-(E)]-6,7-Didehydro-N,4-dimethyl-3-oxo-L-2-aminooctanoic acid]-7-L-valinecyclosporin A; 6-[(2S,4R,6E)-4-Methyl-2-(methylamino)-3-oxo-6-octenoic Acid]ccyclosporin D; Amdray; PSC 833; SDZ-PSC 833; Valpodar. Grades: Highly Purified. CAS No. 121584-18-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
(Z)-Oct-2-enoic acid
(Z)-Oct-2-enoic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Octenoic acid, trans-2-Octenoic acid, Oct-2-enoic acid, 1871-67-6, 1470-50-4, ACMC-209epd, AC1L2KNA, 2-Octenoic acid, (Z)-, NCIOpen2_000192, CTK0B0427, CTK0H7482, CTK8B1077, ANW-23327, NSC 66570, AG-D-91794, 1577-96-4. Product Category: Heterocyclic Organic Compound. CAS No. 1577-96-4. Molecular formula: C8H14O2. Mole weight: 142.195560 [g/mol]. Purity: 0.96. IUPACName: oct-2-enoic acid. Product ID: ACM1577964. Alfa Chemistry ISO 9001:2015 Certified.
Cyclosporine EP Impurity C
A rearranged degradation product formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions. Synonyms: Isocyclosporin A; Iso Cyclosporin A; Ciclosporin EP Impurity C; (2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valine (11?1)-Lactone; Iso Cyclosporin A; Cyclo[L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-[(3R,4R)-3-hydroxy-N-methyl-5-[(E)-1-propenyl]-L-Leu-]]. Grades: ≥90% by HPLC. CAS No. 59865-16-6. Molecular formula: C62H111N11O12. Mole weight: 1202.61.
Griseolic acid A
It is produced by the strain of Streptomyces griseoaurantiacus SANK43894. It has the activity of inhibiting cyclic adenosine monophosphate (cAMP) phosphodiesterase [EC 3.1.4.17] with IC50 0.16 X 10-6 mol/L (Extracted from rat brain). Griseolic acid A can stimulate the flow of glycogen and increase the blood sugar level in mice. Synonyms: griseolic acid; 1-(6-Amino-9H-purin-9-yl)-3,6-anhydro-6-C-carboxy-1,5-dideoxy-α-L-talo-4-octenofuranuronic acid. CAS No. 79030-08-3. Molecular formula: C14H13N5O8. Mole weight: 379.28.
Griseolic acid B
It is produced by the strain of Streptomyces griseoaurantiacus SANK43894. It has the activity of inhibiting cyclic adenosine monophosphate (cAMP) phosphodiesterase [EC 3.1.4.17] with IC50 0.16 X 10-6 mol/L (Extracted from rat brain). Synonyms: (2R,5R,6R,6aS)-5-(6-amino-9H-purin-9-yl)-2-(carboxymethyl)-6-hydroxy-2,5,6,6a-tetrahydrofuro[3,2-b]furan-2-carboxylic acid; Deoxygriseolic Acid; 1-(6-Amino-9H-purin-9-yl)-3,6-anhydro-6-C-carboxy-1,5,7-trideoxy-β-D-ribo-4-octenofuranuronic acid; 7'-Desoxygriseolic acid. CAS No. 98890-01-8. Molecular formula: C14H13N5O7. Mole weight: 363.28.
Iso Cyclosporin H Trifluoroacetic Acid Salt
Iso Cyclosporin H Trifluoroacetic Acid Salt is an impurity of cyclosporin, which is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation. Synonyms: (2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-D-valine (11?1)-Lactone Trifluoroacetic Acid Salt; 10-(N-Methyl-D-valine)isocyclosporin A Trifluoroacetic Acid Salt; Cyclosporine Impurity 19 Trifluoroacetic Acid Salt; D-Valine, (2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-, (11?1)-lactone, Trifluoroacetic Acid Salt; Isocyclosporin H Trifluoroacetic Acid Salt. Grades: ≥90% by HPLC. Molecular formula: C62H111N11O12.C2HF3O2. Mole weight: 1316.63.
It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: Zaragozic acid A; squalestatin 1; Squalestatin; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-(4,6-dimethyl-2-octenoate), (5(2E,4S,6S),7S)-; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-; Squalestatin S1. Grades: >98% by HPLC. CAS No. 142561-96-4. Molecular formula: C35H46O14. Mole weight: 690.73.
Squalestatin B
It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-(4,6-dimethyl-2-octenoate), [5(2E,4S,6S),7S]-; Squalestatin 2; Squalestatin S2. CAS No. 142505-91-7. Molecular formula: C33H44O13. Mole weight: 648.70.
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