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CD Bioparticles provides HA10-Mono AMCA, Fluorescent Oligomeric Hyaluronic Acids for drug delivery. Group: Fluorescent oligomeric hyaluronic acids.
6-aminohexanoate-oligomer endohydrolase
The enzyme is involved in degradation of nylon-6 oligomers. It degrades linear or cyclic oligomers of poly(6-aminohexanoate) with a degree of polymerization greater than three (n > 3) by endo-type cleavage, to oligomers of a length of two or more (2 ≤ x < n). It shows negligible activity with N-(6-aminohexanoyl)-6-aminohexanoate (cf. EC 3.5.1.46, 6-aminohexanoate-oligomer exo hydrolase) or with 1,8-diazacyclotetradecane-2,9-dione (cf. EC 3.5.2.12, 6-aminohexanoate-cyclic-dimer hydrolase). Group: Enzymes. Synonyms: endo-type 6-aminohexanoate oligomer hydrolase; Ahx endo-type-oligomer hydrolase; 6-aminohexanoate oligomer hydrolase; Ahx-oligomer hydrolase; nylon hydrolase; nylon-oligomer hydrolase; NylC; nylon-6 hydrolase (ambiguous). Enzyme Commission Number: EC 3.5.1.117. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4397; 6-aminohexanoate-oligomer endohydrolase; EC 3.5.1.117; endo-type 6-aminohexanoate oligomer hydrolase; Ahx endo-type-oligomer hydrolase; 6-aminohexanoate oligomer hydrolase; Ahx-oligomer hydrolase; nylon hydrolase; nylon-oligomer hydrolase; NylC; nylon-6 hydrolase (ambiguous). Cat No: EXWM-4397.
6-aminohexanoate-oligomer exohydrolase
The enzyme is involved in degradation of nylon-6 oligomers. It degrades linear oligomers of 6-aminohexanoate with a degree of polymerization of 2-20 by exo-type cleavage, removing residues sequentially from the N-terminus. Activity decreases with the increase of the polymerization number of the oligomer. cf. EC 3.5.1.117, 6-aminohexanoate-oligomer endohydrolase and EC 3.5.2.12, 6-aminohexanoate-cyclic-dimer hydrolase. Group: Enzymes. Synonyms: 6-aminohexanoate-dimer hydrolase; nylB (gene name); 6-aminohexanoic acid oligomer hydrolase (ambiguous); N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase; nylon-6 hydrolase (ambiguous). Enzyme Commission Number: EC 3.5.1.46. CAS No. 75216-15-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4434; 6-aminohexanoate-oligomer exohydrolase; EC 3.5.1.46; 75216-15-8; 6-aminohexanoate-dimer hydrolase; nylB (gene name); 6-aminohexanoic acid oligomer hydrolase (ambiguous); N-(6-aminohexanoyl)-6-aminohexanoate amidohydrolase; nylon-6 hydrolase (ambiguous). Cat No: EXWM-4434.
An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Molecular formula: C32H38N6O8S2. Mole weight: 698.81.
Ampicillin oligomer 1 (trimer)
An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. CAS No. 114977-84-3. Molecular formula: C48H57N9O12S3. Mole weight: 1048.21.
Ampicillin oligomer 2
An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Molecular formula: C32H40N6O9S2. Mole weight: 716.82.
Brij L23-d25 (Polidocanol-d25 - Mixture of Oligomers)
Isotope labelled Brij L23 (mixture of oligomers), used in the schlerotherapy treatments, in those suffering from blood vessel malformations and mutations. As well used as an antiinflammatory and other degenerative diseases. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: N/A. US Biological Life Sciences.
Chitosan oligomer (Dp 3-7) - Molecular weight 1000 is a chitosan oligomer with a remarkable molecular weight of 1000. From studying inflammation to expediting wound recovery, this masterpiece emerges as the epitome of groundbreaking drug delivery systems. Molecular formula: (C6H11NO4)n.
A detergent composed of a mixture of alkyl glucosides. Synonyms: ELUGENT Detergent. CAS No. 132778-08-6.
Discrete-HA Oligomeric-HA8
Discrete-HA Oligomeric-HA8 is a monodisperse octameric hyaluronic acid. Hyaluronic acid contributes significantly to cell proliferation and migration, and may also be involved in some malignant tumors progress.
Discrete-HA Oligomeric-HA8
Discrete-HA Oligomeric-HA8 is a monodisperse octameric hyaluronic acid. Hyaluronic acid contributes significantly to cell proliferation and migration, and may also be involved in the progression of some malignant tumors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: NA, Molecular Weight: 1535.3. US Biological Life Sciences.
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Grape Seeds Oligomeric Proanthocyanidins
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Imide-extended bismaleimide oligomer
Imide-extended bismaleimide oligomer. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (1,2-Bis(octylmaleimide)-3-octyl-4-hexyl)cyclohexyl oligomer;2-[8-(3-Hexyl-2,6-dioctylcyclohexyl)octyl]pyromellitic diimide oligomer, maleimide terminated, lower viscosity;BMI-9000P;Imide-extended bismaleimide oligomer;IMide-extended bisMaleiMide, BMI-500. Product Category: Polymer/Macromolecule. CAS No. 921213-77-6. Product ID: ACM921213776. Alfa Chemistry ISO 9001:2015 Certified.
Methacrylated aliphatic urethane oligomer
Methacrylated aliphatic urethane oligomer. Uses: Designed for use in research and industrial production. Additional or Alternative Names: to-1-(isocyanatomethyl)-1,3,3-trimethylcyclohexane,hydroxyethylmethacrylate-b;METHACRYLATED ALIPHATIC URETHANE OLIGOMER;METHACRYLATED ALIPHATIC URETHANE (OLIGOMER) FUNCTIONALITY 2;Poly(oxy-1,4-butanediyl), alpha-hydro-omega-hydroxy-, polymer with 5-isoc. Product Category: Heterocyclic Organic Compound. CAS No. 82339-26-2. Molecular formula: C33H57N3O11. Product ID: ACM82339262. Alfa Chemistry ISO 9001:2015 Certified.
Polybutadiene oligomer,acrylated,mw 7000. Uses: Designed for use in research and industrial production. Product Category: Polymer/Macromolecule. CAS No. 9003-17-2. Mole weight: 7000. Density: 0.91 (25°C). Product ID: ACM9003172-1. Alfa Chemistry ISO 9001:2015 Certified.
Purified Grape Seeds Oligomeric Proanthocyanidins
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Rubber Oligomer 3
Rubber Oligomer 3. Uses: Designed for use in research and industrial production. Appearance: White powder. CAS No. 114123-73-8. Molecular formula: C21H40. Mole weight: 292.55. Purity: 0.98. Product ID: ACM114123738. Alfa Chemistry ISO 9001:2015 Certified.
10-Undecenoic acid,98% (stabilized with TBC)
10-Undecenoic acid (Undecylenic acid) is an antifungal agent. 10-Undecenoic acid inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid has neuroprotective effects. 10-Undecenoic acid has anticancer effects on a variety of tumors. 10-Undecenoic acid inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. Alternative Names: Undecylenic acid. CAS No. 112-38-9. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0914.
10-Undecenoic acid (Standard)
10-Undecenoic acid (Standard) is the analytical standard of 10-Undecenoic acid. This product is intended for research and analytical applications. 10-Undecenoic acid (Undecylenic acid) is an antifungal agent. 10-Undecenoic acid inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid has neuroprotective effects. 10-Undecenoic acid has anticancer effects on a variety of tumors. 10-Undecenoic acid inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa [1] [2] [3] [4] [5] [6] [7] [8]. Uses: Scientific research. Group: Natural products. CAS No. 112-38-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-B0914R.
1,1,1,1-Kestohexaose
1,1,1,1-Kestohexaose is a fructan oligomer isolated from Poa ampla [1]. Uses: Scientific research. Group: Natural products. CAS No. 62512-19-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6838.
Aggregation-induced emission luminogens (AIEgens) such as tetraphenylethene (TPE) functionalized with boronic acids form luminogen (TPE-BA). TPE-BA can form oligoboronates with D-glucose. Other sugars also form monoadduct with TPE-BA, but once such a complex is formed there is no more cis-diol that allows the oligomerization reaction to proceed, resulting in a very low emission intensity. Thus, TPE-BA could serve as a glucose-specific probe. Uses: Tpe-ba is an aggregation-induced emission (aie) dye for use in suzuki reaction and d-glucose detection. Group: Bioelectronic materials organic light-emitting diode (oled) materials other materials. Alternative Names: TPE-BA. CAS No. 1054451-31-8. Pack Sizes: 25 mg in glass insert. Product ID: [4-[(E)-2-(4-boronophenyl)-1,2-diphenylethenyl]phenyl]boronic acid. Molecular formula: 420.07. Mole weight: C26H22B2O4. OB (O)C (C=C1)=CC=C1/C (C2=CC=CC=C2)=C (C3=CC=C (B (O)O)C=C3)\C4=CC=CC=C4. 1S/C26H22B2O4/c29-27 (30)23-15-11-21 (12-16-23)25 (19-7-3-1-4-8-19)26 (20-9-5-2-6-10-20)22-13-17-24 (18-14-22)28 (31)32/h1-18, 29-32H/b26-25+, CFKHFTZRFSABDV-OCEACIFDSA-N. CFKHFTZRFSABDV-OCEACIFDSA-N.
1,3-Bis(4-aminophenyl)urea
1,3-Bis(4-aminophenyl)urea is an inhibitor that directly interacts with VDAC1 and prevents VDAC1 oligomerization. Synonyms: 4,4''-Diaminocarbanilide; N,N'-Bis(4-aminophenyl)urea; 1,3-bis(4-azanylphenyl)urea; NSC15364. CAS No. 4550-72-5. Molecular formula: C13H14N4O. Mole weight: 242.28.
1, 4-Anhydro-5-O-[bis (4-methoxyphenyl) phenylmethyl]-2-deoxy-D-erythro-pentitol is used as a reactant in the solution conformation of an abasic DNA undecamer duplex with unpaired thymine. Also used in direct fluorescence monitoring of uracil DNA glycosylase activity in vitro and in bacterial cells using short single-stranded DNA oligomers containing pyrene α-deoxyriboside adjacent to uracil. Group: Biochemicals. Grades: Highly Purified. CAS No. 95049-01-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C26H28O5, Molecular Weight: 420.5. US Biological Life Sciences.
Worldwide
1, 4-Bis (chloromethyl) naphthalene
1, 4-Bis (chloromethyl) naphthalene is used a reactant commonly used to prepare fluorescent polymers and oligomers. Group: Biochemicals. Grades: Highly Purified. CAS No. 6586-89-6. Pack Sizes: 100mg, 1g. Molecular Formula: C12H10Cl2, Molecular Weight: 225.11. US Biological Life Sciences.
Worldwide
1-Mesyl-2-azidoethanol
1-Mesyl-2-azidoethanol is an intermediate in the synthesis of dopamine D1/D3 heterodimer to Investigate Hetero-Oligomer binding properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 75178-70-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C3H7N3O3S. US Biological Life Sciences.
Worldwide
2,5-Dibromo-3,4-dinitrothiophene
2,5-Dibromo-3,4-dinitrothiophene. Uses: This monomer is useful in the pd catalyzed stille coupling to make conjugated thiophene oligomers or co-oligomers. the corresponding amine(s) can be obtained by subsequent reduction. Group: other electronic materials synthetic tools and reagents. Alternative Names: 2,5-DIBROMO-3,4-DINITROTHIOPHENE; AKOS 92299; 2,5-Dibromo-3,4-dinitrthiphene; 2,5-DIBROMO-3,4-DINITROTHIOPHENE 98+%; 2,5-DibroMo-3,4-dinitrothiophene98%; NSC 84661; DibroMo-3,4-dinitrothio; 2,5-Dibromo-3,4-dinitrothiophene,95%. CAS No. 52431-30-8. Pack Sizes: Packaging 1, 5 g in glass bottle. Product ID: 2,5-dibromo-3,4-dinitrothiophene. Molecular formula: 331.93. Mole weight: C4Br2N2O4S. [O-][N+] (=O)c1c (Br)sc (Br)c1[N+] ([O-])=O. 1S/C4Br2N2O4S/c5-3-1 (7 (9)10)2 (8 (11)12)4 (6)13-3. AHGHPBPARMANQD-UHFFFAOYSA-N. 98%.
2-Amino-1-naphthalenesulfonic Acid
2-Amino-1-naphthalenesulfonic Acid has been used in the preparation of oligomeric acid azo dyes and yields a reddish orange color in the dye. Group: Biochemicals. Grades: Highly Purified. CAS No. 81-16-3. Pack Sizes: 50g, 100 g. Molecular Formula: C10H9NO3S, Molecular Weight: 223.25. US Biological Life Sciences.
Worldwide
2-Amino-2-deoxy-D-arabinose
2-Amino-2-deoxy-D-arabinose is a sugar derivative that has been studied for its use as a binding molecule for the isolation of mannose-binding lectin (MBL) compounds. Isolation of a lectin compound depends on the affinity of the sugar derivative on the solid support to the oligomers of lectin. Synonyms: D-Arabinosamine. CAS No. 52919-00-3. Molecular formula: C5H11NO4. Mole weight: 149.15.
2-Bromo-3-thenyl Bromide
2-Bromo-3-thenyl Bromide was used in preparation of amphiphilic conjugated diblock oligomers as molecular diodes. Group: Biochemicals. Grades: Highly Purified. CAS No. 40032-76-6. Pack Sizes: 250mg, 1g. Molecular Formula: C5H4Br2S, Molecular Weight: 255.96. US Biological Life Sciences.
Worldwide
2-Bromo-5-dodecylthiophene
2-Bromo-5-dodecylthiophene. Uses: Terminal building blocks for semiconducting polymers and oligomers to increase solubility and mobility. Group: Small molecule semiconductor building blockssynthetic tools and reagents polymerssemiconductor blocks. CAS No. 153561-74-1. Pack Sizes: Packaging 1, 5 g in glass bottle. Product ID: 2-bromo-5-dodecylthiophene. Molecular formula: 331.35. Mole weight: C16H27BrS. CCCCCCCCCCCCc1ccc(Br)s1. 1S / C16H27BrS / c1-2-3-4-5-6-7-8-9-10-11-12-15-13-14- 16 (17) 18-15 / h13-14H, 2-12H2, 1H3. MOSAVYMGWTYDNS-UHFFFAOYSA-N.
2-Bromoisobutyric Acid
2-Bromoisobutyric Acid is used in the Herceptin functionalization of polyhedral oligomeric silsesquioxane-conjugated oligomers-silica /iron oxide nanoparticles for tumor cell sorting. Group: Biochemicals. Alternative Names: 2-Bromo-2-methyl-propanoic Acid; α-Bromo-isobutyric Acid; 2-Bromo-2-methyl-propionic Acid; 2-Bromo-2-methylpropanoic Acid; 2-Bromo-2-methylpropionic Acid; 2-Bromoisobutyric Acid; Bromoisobutyric Acid; Isobromobutyric Acid; NSC 41213; α-Bromo-α-methylpropionic Acid; α-Bromoisobutyric Acid. Grades: Highly Purified. CAS No. 2052-1-9. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
2-Chloro-N- (methylsulfonyl) acetamide
2-Chloro-N- (methylsulfonyl) acetamide acts as a reagent for the preparation of piperazinyl quinolonecarboxamide s as antivirals. Solid phase preparation of peptidines, glycine-amidine-based oligomers. Group: Biochemicals. Grades: Highly Purified. CAS No. 202658-88-6. Pack Sizes: 1g, 5g. Molecular Formula: C3H6ClNO3S, Molecular Weight: 171.6. US Biological Life Sciences.
2'-Deoxy-5'-O-DMT-N2-isobutyryl-6-thioguanosine 3-CE phosphoramidite is a crucial component used in the synthesis of nucleic acid oligomers. This phosphoramidite is mainly employed in the biomedical industry for the production of modified DNA or RNA sequences. It enables the incorporation of the N2-isobutyryl-6-thioguanosine moiety during solid-phase synthesis. These modified oligomers find applications in studying DNA-protein interactions and developing potential therapeutics targeting diseases such as cancer and viral infections. CAS No. 125698-85-3. Molecular formula: C44H54N7O7PS. Mole weight: 855.98.
2-Hydroxybenzeneethanol
2-Hydroxybenzeneethanol can be used to synthesize cyclic products and organoaluminim oligomers. Inelastic electron tunnelling spectra of 2-hydroxyphenethyl alcohol adsorbed on thin-film aluminium and magnesium oxide has been investigated. Group: Biochemicals. Grades: Highly Purified. CAS No. 7768-28-7. Pack Sizes: 1g, 5g. Molecular Formula: C8H10O2. US Biological Life Sciences.
Worldwide
2-Iminothiolane, Hydrochloride
A valuable tool in studies of cellular organelles and oligomeric enzymes, using the techniques of protein-protein cross-linking. It may also be used to introduce reactive sulfhydryl groups into proteins for subsequent reaction with alkylating agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 4781-83-3. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
2-O-α-L-Fucopyranosyl-D-galactose
2-O-α-L-Fucopyranosyl-D-galactose is a compound used in the research of neurodegenerative disorders, such as Alzheimer's disease, by inhibiting the formation of beta-amyloid plaques. Uses: A new type of β-propeller architecture formed by oligomerization and interacting with fucoside, fucosyllactose, and plant xyloglucan. Synonyms: 2-O-(6-Deoxy-α-L-galactopyranosyl)-D-galactose; Blood Group H Disaccharide; Fuc1-α-2Gal; Fuc(a1-2)aldehydo-Gal. Grade: 97%. CAS No. 24656-24-4. Molecular formula: C12H22O10. Mole weight: 326.30.
2'-OMe-U-Thiophosphoramidite
2'-OMe-U-Thiophosphoramidite, a chemical compound extensively employed in the production of oligonucleotides for biomedical inquiries, embarks on the critical task of modifying RNA and DNA oligomers' backbone, eliciting their augmented bonding proficiency and stability. Its indispensability, especially in cancer therapy and gene research studies, renders it a boon to molecular biology's advancement and exploration. Synonyms: 5'-Dimethoxytrityl-Uridine, 2'-O-methyl, 3'-[(β-thiobenzoylethyl)-(1-pyrrolidinyl)]-thiophosphoramidite. Molecular formula: C44H48N3O9PS2. Mole weight: 857.97.
?94% (oligomer purity). Group: Poly(ethylene glycol) and poly(ethylene oxide).
4,7-Dibromo-[1,2,5]thiadiazolo[3,4-c]pyridine
4,7-Dibromo-[1,2,5]thiadiazolo[3,4-c]pyridine is a thiadiazolo[3,4-c]pyridine based material that is used as an electron deficient group for organic electronic applications. Uses: 4,7-dibromo-[1,2,5]thiadiazolo[3,4-c]pyridine can be used in the synthesis of panchromatic organic for dye sensitized solar cells (dsscs). this product is used in the synthesis of photoactive acceptor part in low band gap conjugated polymers and oligomers for high performance opv devices. Group: Synthetic tools and reagents. Pack Sizes: Packaging 1, 5 g in glass bottle. Product ID: 4,7-dibromo-[1,2,5]thiadiazolo[3,4-c]pyridine. Molecular formula: 294.95. Mole weight: C5HBr2N3S. BrC1=CN=C(Br)C2=NSN=C21. 1S/C5HBr2N3S/c6-2-1-8-5 (7)4-3 (2)9-11-10-4/h1H. LEHZIBSAFRVAJP-UHFFFAOYSA-N. ≥ 97%.
4-DAMP
4-DAMP (4-DAMP methiodide) is a potent and selective antagonist of M3 receptors and also has a high affinity for the closely-related M5 receptors. 4-DAMP combined with 5-Fluorouracil (5-Fu) (HY-90006) could significantly reduce the cell viability and enhance apoptosis in MKN45 and BGC823 gastric cancer cells. 4-DAMP inhibits lipopolysaccharide (LPS)- and tobacco-induced pulmonary inflammation and reduces mucin 5AC (MUC5AC), oligomeric mucus/gel-forming secretion [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-DAMP methiodide. CAS No. 1952-15-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100958.
4-Nitrophenyl O-β-D-Galactopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→4)-2-(acetylamino)-2-deoxy-β-D-glucopyranoside is an N-acetyllactosamine oligomer that can be useful as a precursor to blood group antigens. It also acts as a substrate for glycosyltransferases in the production of glycoconjugates. Synonyms: Galβ1-4GlcNAcβ1-3Galβ1-4GlcNAcβ-pNP; N-((2S,3R,4R,5S,6R)-2-(((2S,3R,4S,5S,6R)-2-(((2R,3S,4R,5R,6S)-5-Acetamido-4-hydroxy-2-(hydroxymethyl)-6-(4-nitrophenoxy)tetrahydro-2H-pyran-3-yl)oxy)-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)oxy)-4-hydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)acetamide. CAS No. 253136-44-6. Molecular formula: C34H51N3O23. Mole weight: 869.78.
4-Pentynoic acid
4-Pentynoic acid (Propargylacetic acid) is an intermediate to produce biologically active compounds. 4-Pentynoic acid is widely utilized as a building block for the synthesis of eight sequence-defined model oligomers [1]. 4-Pentynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Propargylacetic acid. CAS No. 6089-9-4. Pack Sizes: 1 g. Product ID: HY-Y1230.
5'-Dimethoxytrityl-N-p-isopropyl-phenoxyacetyl-2'-deoxyGuanosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite is a component of great interest in the construction of oligomers involved in transcriptomics. Used notably in gene therapy, this product facilitates the gathering of crucial molecular information aimed at deciphering critical processes such as transcription regulation, gene silencing, and DNA replication. Additionally, with its established role in investigative efforts focused on bettering patient outcomes in a range of cancers and genetic disorders, the extensive utility of this reagent is abundantly clear. Synonyms: iPrPAC-dG CEP. CAS No. 150065-82-0. Molecular formula: C51H60N7O9P. Mole weight: 946.05.
ADS032
ADS032 is a sulfonylurea compound that is an NLRP1 and NLRP3 inflammasome inhibitor. ADS032 reduces the secretion of inflammatory factors and inhibits the oligomerization of ASC. ADS032 has anti-inflammatory effects in a variety of inflammatory models and can be used in the study of inflammatory diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2757333-37-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156798.
ALZ-801
ALZ-801 is a novel and orally available prodrug of tramiprosate that is undergoing a clinical trial for the treatment of Alzheimer's disease (AD). Compared to tramiprosate, ALZ-801 improves some critical properties including tolerability, pharmacokinetic and pharmacodynamic profile, as well as metabolic stability. It inhibits the toxic amyloid oligomers formation associated with AD, which is a discovery of new mechanism of AD prevention. Uses: Prevention of alzheimer's disease (ad). Synonyms: ALZ-801; ALZ 801; ALZ801.
Ampicillin EP Impurity M
An impurity of Ampicillin, an antibiotic used for the treatment of various bacterial infections. Synonyms: co-oligomers of ampicillin and of penicilloic acids of ampicillin.
Anle138b
Anle138b is a novel fluorescent oligomer modulator and an aggregation inhibitor. In vitro, anle138b blocked the formation of pathological aggregates of prion protein (PrPSc) and of α-synuclein. Synonyms: Anle138b; Anle 138b; Anle-138b; 5-(1,3-benzodioxol-5-yl)-3-(3-bromophenyl)-1H-pyrazole; 3-(1,3-benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole; anle138b. CAS No. 882697-00-9. Molecular formula: C16H11BrN2O2. Mole weight: 343.17.
AP20187
Systemic AP20187 administration results in time-dependent LFv2IRE tyrosine phosphorylation and activation of the insulin signaling pathway in both liver and muscle of AAV-treated NOD mice. AP20187 stimulation significantly increases hepatic glycogen content and muscular glucose uptake similarly to insulin. The homodimerizer has been widely used to study signal transduction pathways (by inducing oligomerization of cell surface receptor proteins), but it can be used to induce the activity/re-localization of any protein that is affected by oligomerization. To test the role of homodimerization in kinase activation, we constructed a fusion protein consisting of the SLK catalytic domain (amino acids 1-373) and a modified FK506 binding protein, Fv (Fv-SLK 1-373). Addition of AP20187 (an analog of FK506) enhanced the homodimerization of Fv-SLK 1-373. Synonyms: AP 20187; AP-20187. Grade: >98%. CAS No. 195514-80-8. Molecular formula: C82H107N5O20. Mole weight: 1482.75.
Apoptosis Activator 2
Apoptosis activator 2 is a cell-permeable apoptosis activator that promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. It increases procaspase-9 processing and subsequent caspase-3 activation. It induces apoptosis in tumor cells (IC50 = 4 - 9 μM for leukemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC50 > 40 μM). Synonyms: Apoptosis Activator 2; AAII; N-(3,4-dichlorobenzyl) Isatin. MDK83190; MDK-83190; MDK 83190. CAS No. 79183-19-0. Molecular formula: C15H9Cl2NO2. Mole weight: 306.142.
β-Amyloid (1-42), human TFA
?-Amyloid (1-42) (Amyloid ?-peptide (1-42), human TFA, a 42-amino acid peptide that has not been treated with HFIP, is a brain-penetrant amyloid protein fragment, which can be used in research on Alzheimer's disease and Downs syndrome. ?-Amyloid (1-42), human TFA remaining as a monomer exhibits antioxidant and neuroprotective effects. ?-Amyloid (1-42), human TFA, after being monomericized by HFIP and dissolved in DMSO to form the stock solution, on the one hand, can form soluble oligomers (A?Os) when incubated at 4 ?, which have synaptic toxicity and neurotoxicity; on the other hand, it can be incubated at 37 ? to form insoluble fibrils, with lower neurotoxicity, and participating in the oxidative damage process. A?42 oligomers bind to various neuronal surface receptors (such as PrPc, mGluR5, NMDA receptors, etc.), triggering oxidative stress, calcium homeostasis imbalance, and synaptic toxicity via activating downstream signaling pathways, leading to neuronal dysfunction and death[1][2][3][4][5][6][7]. Uses: Scientific research. Group: Peptides. Alternative Names: Amyloid ?-peptide (1-42) (human) TFA. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1363.
bis(7)-Tacrine
Acetylcholinesterase (AChE) is the primary cholinesterase in the body. It is an enzyme catalyzing the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. Tacrine is an amino acridine compound that inhibits acetylcholinesterase (AChE), which has been proposed as a clinical treatment for Alzheimer's disease. Bis(7)-Tacrine is a tacrine dimer, linked via a 7-carbon alkyl spacer. It inhibits AChE with an IC50 of 0.40 nM, making it more than 1,000 times more potent than tacrine. It is thought to have multiple mechanisms of action including inhibition of AChE, and inihbititon of the amyloid precursor protein/beta-amyloid cascade. It has been shown to inhibit the formation of Aβ1-42 oligomers and reduce the amount of pre-formed Aβ1-42 oligomers. Synonyms: 1,7-N-heptylene-bis-9,9'-amino-1,2,3,4-tetrahydro-acridine. Grade: ≥98%. CAS No. 224445-12-9. Molecular formula: C33H40N4·2HCl. Mole weight: 565.6.
Bisphenol-A Bis(Diphenyl Phosphate)
Bisphenol A Bis(diphenyl phosphate) is a flame retardant. Bisphenol A Bis(diphenyl phosphate) is used in electrical wire covering and other flame resistant materials. Synonyms: Bisphenol-A Bis(Diphenyl Phosphate); BISPHENYL A BIS (DIPHENYL PHOSPHATE) BDP; Phosphoric acid, (1-methylethylidene)di-4,1-phenylene tetraphenyl ester; Bisphenol-A-di(diphenylphosphat); OLIGOMERICBISPHENYLABIS(DIPHENYLPHOSPHATE); Flameretardant plasticizer BDP. Grade: 95%. CAS No. 5945-33-5. Molecular formula: C39H34O8P2. Mole weight: 692.63.
Boc-PNA-A(Z)-OH
A Boc PNA monomer that is a building block for the synthesis of PNA oligomers. Synonyms: Boc-A(Z)-Aeg-OH. Grade: 98%. CAS No. 149376-69-2. Molecular formula: C24H29N7O7. Mole weight: 527.54.
Boc-PNA-C(Z)-OH
A Boc PNA monomer that is a building block for the synthesis of PNA oligomers. Synonyms: Boc-C(Z)-Aeg-OH; N-(2-(4-(((Benzyloxy)carbonyl)amino)-2-oxopyrimidin-1(2H)-yl)acetyl)-N-(2-((tert-butoxycarbonyl)amino)ethyl)glycine. Grade: 95%. CAS No. 144564-94-3. Molecular formula: C23H29N5O8. Mole weight: 503.51.
Boc-PNA-D(tetraZ)-OH
A Boc PNA monomer that is a building block for the synthesis of PNA oligomers. Grade: 98%. Molecular formula: C48H48N8O13. Mole weight: 944.96.
Boc-PNA-G(Z)-OH
Boc-PNA-G(Z)-OH is a synthetic peptide nucleic acid (PNA) monomer with a guanine base. It features a Boc (tert-butyloxycarbonyl) protecting group and a Z (benzyloxycarbonyl) group, commonly used in the synthesis of PNA oligomers for research in molecular biology and genetics, particularly in the study of DNA and RNA binding. Synonyms: N-((N2-(Benzyloxycarbonyl)guanine-9-yl)acetyl)-N-(2-Boc-aminoethyl)glycine; Boc-G(Z)-Aeg-OH; Glycine, N-[[1,6-dihydro-6-oxo-2-[[(phenylmethoxy)carbonyl]amino]-9H-purin-9-yl]acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]-; N-[2-[1,6-Dihydro-6-oxo-2-[[(phenylmethoxy)carbonyl]amino]-9H-purin-9-yl]acetyl]-N-[2-[[(1,1-dimethylethoxy)carbonyl]amino]ethyl]glycine. Grade: ≥97% by HPLC. CAS No. 169287-77-8. Molecular formula: C24H29N7O8. Mole weight: 543.54.
Boc-PNA-J(Z)-OH
A Boc PNA monomer that is a building block for the synthesis of PNA oligomers. Synonyms: Boc-J(Z)-Aeg-OH. Grade: 98%. CAS No. 163081-03-6. Molecular formula: C23H29N5O8. Mole weight: 503.51.
Boc-PNA-M(Z)-OH
A Boc PNA monomer that is a building block for the synthesis of PNA oligomers. Grade: 98%. Molecular formula: C24H30N4O7. Mole weight: 486.53.
Boc-PNA-thioU(PMB)-OH
A Boc PNA monomer that is a building block for the synthesis of PNA oligomers. Synonyms: Boc-thioU(PMB)-OH. Grade: 98%. CAS No. 253438-99-2. Molecular formula: C23H30N4O7S. Mole weight: 506.57.
Boc-PNA-U-OH
A Boc PNA monomer that is a building block for the synthesis of PNA oligomers. Grade: 98%. CAS No. 149500-74-3. Molecular formula: C15H22N4O7. Mole weight: 370.36.
CAM833
CAM833 is a potent orthosteric inhibitor of the interaction between BRCA2 and RAD51 with a Kd of 366 nM against the ChimRAD51 protein. CAM833 also inhibits RAD51 oligomerization. CAM833 increases the progression of G2/M-arrested cells into apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2758364-02-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150147.
Chitosan oligosaccharide
Chitosan oligosaccharide (COS) is an oligomer of β-(1→4)-linked D-glucosamine. Chitosan oligosaccharide (COS) activates AMPK and inhibits inflammatory signaling pathways including NF-κB and MAPK pathways. Uses: Scientific research. Group: Natural products. Alternative Names: COS. CAS No. 148411-57-8. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-112108.
Choline Kinase (Crude Enzyme)
Choline kinase (also known as CK,ChoK and choline phosphokinase) is an enzyme which catalyzes the first reaction in the choline pathway for phosphatidylcholine (PC) biosynthesis. This reaction involves the transfer of a phosphate group from adenosine triphosphate (ATP) to choline in order to form phosphocholine. Thus, the two substrates of this enzyme are ATP and choline, whereas its two products are adenosine diphosphate (ADP) and O-phosphocholine. Choline kinase requires magnesium ions (+2) as a cofactor for this reaction. This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol grou. CHKA and CHKB and are only active in their homodimeric, heterodimeric and oligomeric forms. This product with the indicated enzyme activity was briefly purified from engineered E. coli. Applications: Biotechnology; diagnostics; drug development; medicine. Group: Enzymes. Synonyms: Choline Kinase (phosphorylating); choline phosphokinase; choline-ethanolamine kinase. Enzyme Commission Number: EC 2.7.1.32. CAS No. 9026-67-9. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. Choline Kinase (phosphorylating); choline phosphokinase; choline-ethanolamine kinase. Pack: 100ml. Cat No: NATE-1825.
Citrullinated amyloid-β (1-42) peptide (human)
Citrullinated amyloid-? (1-42) peptide (human) (Citrullinated A? (1-42)) is a modified form of ?-Amyloid (1-42) (HY-P1363) with a citrullination at the Arg5 site. Compared to the unmodified ?-Amyloid (1-42), its formation of soluble low-molecular-weight oligomers is enhanced, the rate of fibril formation is reduced, and like unmodified A?42, it forms protofibrils comprised of parallel ?-sheets[1]. Uses: Scientific research. Group: Peptides. Alternative Names: Citrullinated A? (1-42); Citrullinated A?42. Pack Sizes: 1 mg. Product ID: HY-P5905.
cobaltochelatase
This enzyme, which forms part of the aerobic cobalamin biosynthesis pathway, is a type I chelatase, being heterotrimeric and ATP-dependent. It comprises two components, one of which corresponds to CobN and the other is composed of two polypeptides, specified by cobS and cobT in Pseudomonas denitrificans, and named CobST. Hydrogenobyrinic acid is a very poor substrate. ATP can be replaced by dATP or CTP but the reaction proceeds more slowly. CobN exhibits a high affinity for hydrogenobyrinic acid a,c-diamide. The oligomeric protein CobST possesses at least one sulfhydryl group that is essential for ATP-binding. Once the Co2+ is inserted, the next step in the pathway ensures that the cobalt is ligated securely by reducing Co(II) to Co(I). This step is carried out by EC 1.16.8.1, cob(II)yrinic acid a,c-diamide reductase. Group: Enzymes. Synonyms: hydrogenobyrinic acid a,c-diamide cobaltochelatase; CobNST; CobNCobST. Enzyme Commission Number: EC 6.6.1.2. CAS No. 81295-49-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5828; cobaltochelatase; EC 6.6.1.2; 81295-49-0; hydrogenobyrinic acid a,c-diamide cobaltochelatase; CobNST; CobNCobST. Cat No: EXWM-5828.
Crenezumab
Crenezumab is a humanized monoclonal antibody that targets β-amyloid oligomers. Crenezumab has been investigated for the treatment of early AD. Synonyms: RG 7412; RG-7412; RG7412. Grade: 95%. CAS No. 1095207-05-8. Molecular formula: C6442H9966N1706O2018S40. Mole weight: 144.9 kDa.
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