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| Product | Description | |
|---|---|---|
| Para Red | Para Red. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences. |  Worldwide |
| Para Red-[d4] | Para Red-[d4] is the labelled analogue of Para Red, which is a biological stain. Uses: A biological stain. Synonyms: Para Red D4; 1-(4-Nitrophenylazo)-2-naphthol-d4; Britelite Toner RP 9-d4; Label Red-d4. Grade: 95% atom D. CAS No. 1185235-75-9. Molecular formula: C16H7D4N3O3. Mole weight: 297.3. |  |
| Para Red-d4 (1-(4-Nitrophenylazo)-2-naphthol-d4) | A biological stain. Group: Biochemicals. Alternative Names: 1-(4-Nitrophenylazo)-2-naphthol-d4. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 1,2-O-Cyclohexylidene-a-D-xylopentodi-aldo-1,4-fructose | 1,2-O-Cyclohexylidene-a-D-xylopentodi-aldo-1,4-fructose is a complex sugar analog of paramount significance and specific application in the biomedical realm. Its potential as a reversible inhibitor of glycolysis in cancer cells has been thoroughly investigated, exhibiting a marked reduction in glucose uptake. This unique compound holds promise for future advancements as a targeted treatment for various types of cancer, bestowed with the ability to selectively hamper unwanted metabolic activity. Synonyms: 1,4-Fructofuranosyl-2-cyclohexylidene-α-D-xylopyranoside. | |
| 3-Acetylpyridine adenine dinucleotide phosphate sodium salt | 3-Acetylpyridine adenine dinucleotide phosphate sodium salt is a highly potent and essential coenzyme employed extensively in diverse biomedical areas, exhibiting paramount significance in cellular energy metabolism. Furthermore, it finds common employment in investigating redox reactions and enzyme kinetics. Synonyms: Adenosine 5'-(trihydrogen diphosphate), 3'-(dihydrogen phosphate), P'→5'-ester with 3-acetyl-1-β-D-ribofuranosylpyridinium, inner salt, disodium salt. CAS No. 102029-67-4. Molecular formula: C22H29N6O17P3.2Na. Mole weight: 788.40. | |
| (3R,5R)-Fluvastatin Sodium Salt | 3R,5R)-Fluvastatin Sodium Salt is a prominent compound in the biomedical industry, aiding in the research of hypercholesterolemia. As a member of the esteemed statin class, it exerts its action by effectively inhibiting the pivotal enzyme HMG-CoA reductase. This paramount compound is frequently recommended to ameliorate LDL cholesterol levels. Grade: > 95%. Molecular formula: C24H25FNO4Na. Mole weight: 433.46. | |
| 4-Hydroxy Atorvastatin-[d5] Calcium Salt | 4-Hydroxy Atorvastatin-[d5] Calcium Salt is the labelled analogue of 4-Hydroxy Atorvastatin Calcium Salt, which is a metabolite of Atorvastatin. Atorvastatin is a selective, competitive inhibitor of HMG-CoA reductase. Synonyms: 4-Hydroxy Atorvastatin D5 Calcium Salt; di((βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-4-[[(4-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-(phenyl-d5)-1H-pyrrole-1-heptanoic Acid) Calcium Salt; p-hydroxy Atorvastatin-(phenyl-d5) Calcium salt; 4-hydroxy Atorvastatin-(phenyl-d5) Calcium salt; para-hydroxy Atorvastatin-(phenyl-d5) Calcium salt; di(4-Hydroxy Atorvastatin-d5) Calcium Salt. Grade: ≥93%; ≥99% atom D. CAS No. 265989-45-5. Molecular formula: C66H58D10CaF2N4O12. Mole weight: 1199.42. | |
| 4-Hydroxy Atorvastatin Lactone-[d5] | 4-Hydroxy Atorvastatin Lactone-[d5] is the labelled analogue of 4-Hydroxy Atorvastatin Lactone, which is a metabolite of Atorvastatin. Atorvastatin is a selective, competitive HMG-CoA reductase inhibitor. Synonyms: 4-Hydroxy Atorvastatin Lactone D5; para-Hydroxy Atorvastatin-d5 Lactone; 5-(4-Fluorophenyl)-N-(4-hydroxyphenyl)-2-(1-methylethyl)-4-phenyl-1-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1H-pyrrole-3-carboxamide-d5. Grade: ≥96% by HPLC; ≥98% atom D. CAS No. 265989-49-9. Molecular formula: C33H28D5FN2O5. Mole weight: 561.65. | |
| 5-(3-Amino-1-propyn-1-yl)-2'-deoxyuridine 5'-(Tetrahydrogen Triphosphate) | 5-(3-Amino-1-propyn-1-yl)-2'-deoxyuridine 5'-(Tetrahydrogen Triphosphate) is an intermediate in the synthesis of Texas Red-5-dUTP, a fluorescence-labelled nucleotide analog. Texas Red-5-dUTP is used diagnostically for detection of rearranged SS18 in formalin-fixed, paraffin-embedded synovial sarcoma. Synonyms: 5-ap-2'-dUTP; 5-Propargylamino-dUTP; 5-Propargylamino-2'-deoxyuridine-5'-Triphosphate; ap-dUTP; 5-(3-Amino-1-propyn-1-yl)-2'-deoxyuridine 5'-triphosphate; 5-PA-dUTP. Grade: ≥90% by AX-HPLC. CAS No. 179101-49-6. Molecular formula: C12H18N3O14P3. Mole weight: 521.20. | |
| 5-Iodo-dUTP | 5-Iodo-dUTP is used in the synthesis of Texas Red-5-dUTP, a fluorescence-labelled nucleotide analog. Texas Red-5-dUTP is used diagnostically for detection of rearranged SS18 in formalin-fixed, paraffin-embedded synovial sarcoma. Synonyms: 5-Iodo-2'-deoxyuridine-5'-Triphosphate. Grade: ≥ 95% by HPLC. CAS No. 3731-55-3. Molecular formula: C9H14N2O14P3I (free acid). Mole weight: 594.04 (free acid). | |
| 6-Chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole (Triclabendazole) | Triclabendazole is a member of the benzimidazole family of anthelmintics. It is effective against F. hepatica helminths that cause fascioliasis, reducing secreted protease enzyme activities that are critical for the invasion, migration, nutrition, and survival of the parasite.1 In yeast and mammalian cells, triclabendazole was shown to inhibit adenylyl cyclase in the Ras-adenylyl cyclase-protein kinase A nutrient-sensing pathway and to prevent apoptosis induced by the Parkinsons disease-related protein α-synuclein, demonstrating a protective role during various cellular stresses.2,3. Group: Biochemicals. Alternative Names: 5-Chloro-6- (2, 3-dichlorophenoxy) -2- methyl thiobenzimidazole; CGA-89317, egaten; Fasinex; Triclabendazole. Grades: Highly Purified. CAS No. 68786-66-3. Pack Sizes: 25g, 50g, 100g. Molecular Formula: C14H9Cl3N2OS, Molecular Weight: 359.66. US Biological Life Sciences. | Worldwide |
| Acetaminophen D-glucuronide | Acetaminophen D-glucuronide, a vital metabolite of acetaminophen, an extensively employed non-prescription remedy for pain alleviation and fever reduction, assumes a pivotal function in dismantling and purging acetaminophen from the organism. Gaining profound comprehension of its synthesis and excreting pathway is paramount in investigating pharmaceutical metabolism and plausible drug interactions. Synonyms: Paracetamol-O-D-glucuronide p-Acetylaminophenol-O-D-glucuronide. CAS No. 16110-10-4. Molecular formula: C14H17NO8. Mole weight: 327.29. | |
| AF 353 | AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist. It is a highly potent inhibitor of α,β-meATP-evoked intracellular calcium flux in cell lines expressing recombinant rat and human P2X3 and human P2X2/3 channels. It also blocks human P2X2/3 channel function with marginally reduced potency (pIC50 = 7.3). It significantly reduces this parameter in both groups. It also reduces the inter-contractile interval in control but not in SCI rats. Synonyms: AF353; AF-353; 2,4-Pyrimidinediamine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-; Ro 4; 5-{[5-iodo-2-(1-Methylethyl)-4-(Methyloxy)phenyl]oxy}-2,4-pyrimidinediamine. Grade: >98%. CAS No. 865305-30-2. Molecular formula: C14H17IN4O2. Mole weight: 400.21. | |
| all cis-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester | all cis-5,8,11,14,17-Eicosapentaenoic Acid Ethyl Ester is an omega-3 fatty acid agent. It is important polyunsaturated fatty acid of the marine food chain. It serves as a precursor of the prostaglandin-3 and thromboxane-3 families. It differs from arachidonic acid by the extra double bond between the third and fourth carbons from the "methyl end" of the molecule. It reduces non-high-density lipoprotein cholesterol, lipoprotein-associated phospholipase A2, apolipoprotein B, very low-density lipoprotein cholesterol, and total cholesterol. It reduces the TG levels and improved other lipid parameters without significantly increasing the LDL cholesterol levels. It is used in combination with changes in diet to lower triglyceride levels in adults with severe (≥ 500 mg/dL) hypertriglyceridemia. It has anti-inflammatory and cardiovascular benefits. It may alter the expression of genes related to fatty acid metabolism. It was the second class of fish oil-based drug to be approved for use as a drug. It was developed by Amarin Corporation. It has been listed. Uses: All cis-5,8,11,14,17-eicosapentaenoic acid ethyl ester reduces non-high-density lipoprotein cholesterol, lipoprotein-associated phospholipase a2, apolipoprotein b, very low-density lipoprotein cholesterol, and total cholesterol. it has anti-inflammatory and cardiovascular benefits. Synonyms: Eicosapentaenoic Acid Ethyl Ester; (5Z, | |
| Anti-Parasitic Compound Library | A selection of 336 compounds with anti-parasitic activity, a powerful tool for anti-parasitic drug development. - Contains a wide range of compounds with anti-parasitic activity, including anti-Plasmodium, anti-Leishmania, and anti-filariasis etc. - Detailed instructions, compound structure, target information, activity description, etc. - Multiple assays such as NMR, HPLC/LCMS to ensure correct product structure, high purity and to reduce false positives. Uses: Scientific use. Product Category: L4510. Categories: Anti-Parasitic Compounds Libraries. |  |
| Artemether | Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.Target: AntiparasiticArtemether is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with lumefantrine for improved efficacy. Artemether exhibits the highest activity against juvenile stages of the parasites, while adult worms are significantly less susceptible. There was no indication of neurotoxicity following repeated high doses of artemether given fortnightly for up to 5 months. Artemether-integrated with other control strategies-has considerable potential for reducing the current burden of schistosomiasis in different epidemiological settings. There were remarkably inhibitory effects of artmeter on brain glioma growth and angiogenesis in SD rats and the mechanism that artemether inhibited brain glioma growth might be penetrating the blood-brain barrier and inhibiting angiogenesis. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 71963-77-4. Molecular formula: C16H26O5. Mole weight: 298.37. Purity: 0.98. Canonical SMILES: C[C@H]1[C@@H](OC)O[C@@]2([H])[C@]34[C@@]([C@H](C)CC[C@]41[H])([H])CC[C@@](O2)(C)OO3. Product ID: ACM71963774. Alfa Chemistry ISO 9001:2015 Certified. |  |
| AS-2444697 HCl | AS-2444697 is a pootent and selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor (IC50 = 21 nM) with 30-fold selectivity for IRAK4 over IRAK1. AS2444697 significantly reduced or showed a decreasing trend in expression and levels of these inflammatory parameters. Synonyms: N-(3-carbamoyl-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)-2-(2-methylpyridin-4-yl)oxazole-4-carboxamide hydrochloride; AS-2444697; AS 2444697; AS2444697; AS-2444697 HCl; AS-2444697 hydrochloride. CAS No. 1287665-60-4. Molecular formula: C19H21ClN6O4. Mole weight: 432.86. | |
| Atranorin | Atranorin, which can be found in the herbs of Parmelia tinctorum Despr, has a relevant redox-active action, acting as a pro-oxidant or antioxidant agent depending on the radical. Also, it will exert cytoprotective effects on cells under oxidative stress induced by H(2)O(2). It was found to be more efficient at equitoxic doses and correlated more strongly with an increased number of floating cells or a higher apoptotic index. It also exhibited significant anti-inflammatory activity in the acute model of inflammation (leukocyte migration to the peritoneal cavity), carrageenan- and arachidonic acid-induced hind paw edema in rats. Besides, Atranorin exhibited a dose-dependent antioxidant activity in vitro, as assessed by total radical-trapping antioxidant parameter and total antioxidant reactivity assays. Uses: Antinociceptive/antiinflammatory/antibacterial. Synonyms: Atranoric acid; Atranorine; Parmelin; Usnarin; Benzoic acid, 3-formyl-2,4-dihydroxy-6-methyl-, 3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester. Grade: 98%. CAS No. 479-20-9. Molecular formula: C19H18O8. Mole weight: 374.34. | |
| BKI-1369 | BKI-1369 is an inhibitor of bumped kinase. BKI-1369 increases human Ether-a-go-go-related gene (hERG)-inhibitory activity with an IC50 of 1.52 μM. BKI-1369 reduces the parasite burden and diseases severity in the gnotobiotic pig model. Synonyms: NSC-787228. Grade: 99%. CAS No. 1951431-22-3. Molecular formula: C23H27N7O. Mole weight: 417.51. | |
| Calcitonin | Calcitonin is a hormone produced by the parafollicular cells (C-cells) of the thyroid gland. It plays a crucial role in calcium homeostasis by lowering blood calcium levels, opposing the actions of parathyroid hormone (PTH), which increases calcium levels. Calcitonin achieves this by inhibiting osteoclast activity, reducing bone resorption, and decreasing calcium reabsorption in the kidneys. It is also involved in phosphate regulation, lowering blood phosphate levels. In clinical settings, calcitonin has been used to treat conditions such as hypercalcemia, Paget's disease of bone, and osteoporosis. Synonyms: Calcitrin; TCA; TCT; Thyrocalcitonin; Thyrocalcitonins. Grade: 95%. CAS No. 9007-12-9. | |
| Calcitonin (swine) | Calcitonin (swine) is a polypeptide hormone that plays a significant role in regulating calcium homeostasis and bone metabolism. It is secreted by the parafollicular cells (C-cells) of the thyroid gland in pigs. Calcitonin inhibits osteoclast activity, thereby reducing bone resorption and lowering serum calcium levels. Additionally, it promotes calcium excretion by the kidneys, further aiding in calcium regulation. In swine, calcitonin is involved in protecting the skeleton from excessive bone mineral loss during periods of high calcium demand, such as lactation. This protective effect is primarily mediated through the inhibition of osteoclastic resorption. The hormone is also implicated in preventing postprandial hypercalcemia resulting from calcium absorption. Synonyms: L-Prolinamide, L-cysteinyl-L-seryl-L-asparaginyl-L-leucyl-L-seryl-L-threonyl-L-cysteinyl-L-valyl-L-leucyl-L-seryl-L-alanyl-L-tyrosyl-L-tryptophyl-L-arginyl-L-asparaginyl-L-leucyl-L-asparaginyl-L-asparaginyl-L-phenylalanyl-L-histidyl-L-arginyl-L-phenylalanyl-L-serylglycyl-L-methionylglycyl-L-phenylalanylglycyl-L-prolyl-L-α-glutamyl-L-threonyl-, cyclic (1→7)-disulfide; Calcitonin (pig); Thydrocalcit. Grade: 95%. CAS No. 12321-44-7. Molecular formula: C159H232N46O45S3. Mole weight: 3604.02. | |
| Carboplatin | Analog of Cisplatin with reduced nephrotoxicity. Carboplatin is a platinum-based antineoplastic drug that damages DNA by forming intrastrand cross-links with neighboring guanine residues. Tumors acquire resistance to these drugs through the loss of DNA-mismatch repair (MMR) activity and the resultant decrease in the induction of programmed cell death. Group: Biochemicals. Alternative Names: (SP-4-2)-Diamimine[1, 1-cyclobutanedi (carboxylato-kO) (2-)]platinum; cis-Diammine (1, 1-cyclobutane dicarboxylato) platinum (II) ; CBDCA; JM-8; Paraplatin. Grades: Purified. CAS No. 41575-94-4. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Carboplatin-d4 ((SP-4-2)-Diamimine[1,1-cyclobutane-d4-di(carboxylato-kO)(2-)]platinum,. cis-Diammine (1, 1-cyclobutane-d4-dicarboxylato)platinum (II), CBDCA-d4, JM-8-d4, Paraplatin-d4) | Analog of Cisplatin with reduced nephrotoxicity. Antineoplastic. Group: Biochemicals. Alternative Names: (SP-4-2)-Diamimine[1,1-cyclobutane-d4-di(carboxylato-kO)(2-)]platinum; cis-Diammine (1, 1-cyclobutane-d4-dicarboxylato)platinum (II); CBDCA-d4; JM-8-d4; Paraplatin-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| CAY10512 | NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. CAY10512 is an analog of Resveratrol that is 100-fold more potent (IC50 = 150 nM) at inhibiting NF-κB activation by TNF-α. Unlike Resveratrol and some other trans-stilbene analogs, CAY10512 does not exhibit antioxidant activity (up to 15 μM) in either the ferric reducing/antioxidant power (FRAP) or total radical antioxidant parameter (TRAP) assays. Synonyms: (E)-2-Fluoro-4?-methoxystilbene. Grade: ≥97%. CAS No. 139141-12-1. Molecular formula: C15H13FO. Mole weight: 228.3. | |
| CAY10575 | NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is activated upon degradation of IκB following IKK-α and IKK-β phosphorylation. IKK-ε, a homolog of IKK-α and IKK-β, can also activate NF-κB. CAY10512 is an analog of Resveratrol that is 100-fold more potent with IC50 of 150 nM at inhibiting NF-κB activation by TNF-α. It does not exhibit antioxidant activity in either the ferric reducing/antioxidant power (FRAP) or total radical antioxidant parameter (TRAP) assays. Synonyms: CAY 10575; CAY-10575. Grade: ≥95%. CAS No. 916985-21-2. Molecular formula: C22H21N3O6S2. Mole weight: 487.6. | |
| Chymostatin | Chymostatin is a SARS-CoV-2 M pro inhibitor. Chymostatin up-regulates endocan and inhibits NF-κBp65 activity. Chymostatin reduces proinflammatory cytokines ( IL-1β and IL-6 ) and HMGB1. Chymostatin shows protective effects against Paraquat-induced acute lung injury. Chymostatin exhibits anticancer activity against lung cancer [1] [2] [3] [4] [5] [6] [7]. Uses: Scientific research. Group: Peptides. CAS No. 9076-44-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P3042. |  |
| Citrullinated amyloid-β (1-42) peptide (human) | Citrullinated amyloid-? (1-42) peptide (human) (Citrullinated A? (1-42)) is a modified form of ?-Amyloid (1-42) (HY-P1363) with a citrullination at the Arg5 site. Compared to the unmodified ?-Amyloid (1-42), its formation of soluble low-molecular-weight oligomers is enhanced, the rate of fibril formation is reduced, and like unmodified A?42, it forms protofibrils comprised of parallel ?-sheets[1]. Uses: Scientific research. Group: Peptides. Alternative Names: Citrullinated A? (1-42); Citrullinated A?42. Pack Sizes: 1 mg. Product ID: HY-P5905. | |
| CKD-516 HCl | CKD-516 is tubulin inhibitor for solid cancer, which was initiated phase 1 trial in Korea in 2010. CKD-516 selectively disrupted tubulin component of the endothelial cytoskeleton. Serial DCE-MRI showed a significant decrease in K-trans and IAUGC parameters from baseline at 4 h (39.9 % in K-trans; -45.0 % in IAUGC) and at 24 h (-32.2 % in K-trans; -36.5 % in IAUGC), and a significant recovery at 48 h (22.9 % in K-trans; 34.8 % in IAUGC) following administration of CKD-516 at a 0.7-mg/kg dose. When the tumors were stratified according to the initial K-trans value of 0.1, tumors with a high K-trans?>?0.1 which was indicative of having well-developed pre-existing vessels, showed greater reduction in K-trans and IAUGC values. On histologic examination, the degree of necrosis of treated tumors was significantly greater than that of untreated tumors. In summary, CKD-516 is an effective VDA which results in rapid vascular shutdown by targeting the tubulin component of tumor vessels and thus leads to necrosis. Synonyms: Valecobulin hydrochloride; CKD516 hydrochloride; CKD 516 hydrochloride. CAS No. 1240321-53-2. Molecular formula: C26H29ClN6O5S. Mole weight: 573.07. | |
| Dabcyl acid | Dabcyl acid (Dabcyl) is the original dark fluorescence quencher. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: DABCYL; Para-methyl red. CAS No. 6268-49-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-D1045. | |
| Demecarium bromide | Demecarium is a parasympathomimetic that acts as an acetylcholinesterase inhibitor. It is one of several topical (applied directly to the affected area) medications used to reduce elevated intraocular pressure (IOP) associated with primary glaucoma in cats, dogs, and other animals. Uses: Cholinesterase inhibitors; miotics. Synonyms: 3,3'-[1,10-decanediylbis[(methylimino)carbonyloxy]]bis[N,N,N-trimethylbenzenaminium Bromide; (m-Hydroxyphenyl)trimethylammonium Bromide Decamethylenebis[methylcarbamate]; (m-hydroxyphenyl)trimethylammonium Bromide Decamethylenebis[methylcarbamate]; Demekarium Bromide; Demekastigmine Bromide; Frumtosnil; Humorsol. Grade: ≥95%. CAS No. 56-94-0. Molecular formula: White Solid. Mole weight: 716.59. | |
| D-Glucono-1,4-lactone | D-Glucono-1,4-lactone is a ubiquitous biochemical compound serving as a paramount precursor for the biosynthesis of L-ascorbic acid. Its latent potential as a paramount reducing compound invigorates its inclusion in numerous medicinal formulations. CAS No. 1198-69-2. Molecular formula: C6H10O6. Mole weight: 178.14. | |
| Dihydrotachysterol | Dihydrotachysterol is a vitamin D that can be regarded as a reduction product of vitamin D2 activated in the liver. It does not require renal hydroxylation like vitamin D2 and vitamin D3. It could stimulate intestinal calcium absorption and increases renal phosphate excretion. It is widely used for hypocalcemic hypoparathyroidism following surgical removal of parathyroids. Synonyms: HSDB 3314; Hytakerol; Parterol; Tachyrol; Dihydral; (1S,3E,4S)-4-Methyl-3-[(2E)-2-[(1R,3aS,7aR)-octahydro-7a-methyl-1-[(1R,2E,4R)-1,4,5-trimethyl-2-hexen-1-yl]-4H-onden-4-ylidene]ethylidene]cyclohexanol; (3β,5E,7E,10α,22E)-9,10-Secoergosta-5,7,22-trien-3-ol; 24-Methyl-9,10-secocholesta-5,7,22-trien-3β-ol; Antitanil; Calcamine; DHT2; Dichystrolum; Dihidrotaquisterol; (5E,7E,22E)-(3S,10S)-9,10-seco-5,7,22-ergostatrien-3-ol. Grade: 98%. CAS No. 67-96-9. Molecular formula: C28H46O. Mole weight: 398.66. | |
| DNDI-6174 | DNDI-6174 is a cytochrome bc1 complex inhibitor with potent in vitro activity against a variety of Leishmania species. DNDI-6174 can reduce parasite burden in animal models of infection [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2868298-43-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162066. | |
| Eprinomectin B1b | It is a semi-synthetic analogue of avermectin B1b prepared by oxidation of the 4''-hydroxy moiety and reductive amination followed by acetylation. It is the minor component (<10%) of the commercial product for endo- and exo-parasite control, eprinomectin. It is a potent insecticide and acaricide. Synonyms: (4''R)-4''-(Acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4''-deoxy-25-(1-methylethyl)avermectin A1a; Eprinomectin component B1b. Grade:>99% by HPLC. CAS No. 133305-89-2. Molecular formula: C49H73NO14. Mole weight: 900.10. | |
| Etelcalcetide hydrochloride | Etelcalcetide is a calcium-sensing receptor agonist as a D-amino peptide calcimimetic for the treatment of secondary hyperparathyroidism. It can bind to and activate the CaSR (calcium-sensing receptor) in the parathyroid gland as an allosteric activator, resulting in PTH reduction and suppression. Amgen Inc. announced its submission of a New Drug Application to the FDA for etelcalcetide in Aug 2015. Synonyms: AMG-416; AMG 416; AMG416; Etelcalcetide hydrochloride; KAI-4169; KAI-4169-HCl; ONO-5163; Parsabiv; Telcalcetide; Velcalcetide; Velcalcetide hydrochloride; N-Acetyl-D-cysteinyl-D-alanyl-D-arginyl-D-arginyl-D-arginyl-D-alanyl-D-argininamide disulfide with L-cysteine hydrochloride; 1262780-97-1 (free). Grade: >98%. CAS No. 1334237-71-6. Molecular formula: C38H74ClN21O10S2. Mole weight: 1084.72. | |
| ferric-chelate reductase (NADH) | Contains FAD. The enzyme catalyses the reduction of bound ferric iron in a variety of iron chelators (siderophores), resulting in the release of ferrous iron. The plant enzyme is involved in the transport of iron across plant plasma membranes. The enzyme from the bacterium Paracoccus denitrificans can also reduce chromate. cf. EC 1.16.1.9, ferric-chelate reductase (NADPH) and EC 1.16.1.10, ferric-chelate reductase [NAD(P)H]. Group: Enzymes. Synonyms: ferric chelate reductase (ambiguous); iron chelate reductase (ambiguous); NADH:Fe3+-EDTA reductase; NADH2:Fe3+ oxidoreductase; ferB (gene name); Fe(II):NAD+ oxidoreductase. Enzyme Commission Number: EC 1.16.1.7. CAS No. 120720-17-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1072; ferric-chelate reductase (NADH); EC 1.16.1.7; 120720-17-4; ferric chelate reductase (ambiguous); iron chelate reductase (ambiguous); NADH:Fe3+-EDTA reductase; NADH2:Fe3+ oxidoreductase; ferB (gene name); Fe(II):NAD+ oxidoreductase. Cat No: EXWM-1072. |  |
| Flubendazole | Flubendazole is an anthelmintic drug based on altering microtubule structure, inhibition of tubulin polymerization and disruption of microtubule function. Flubendazole induces apoptosis in human colorectal cancer (CRC) by blocking the STAT3 signaling axis and activation of autophagy. Flubendazole induces P53 expression and reduced Cyclin B1 and p-cdc2 expression. Flubendazole is an antitumor agent. Flubendazole can be used for worm and intestinal parasites [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 31430-15-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0294. | |
| Flunarizine | Flunarizine is a selective calcium entry blocker, which has calmodulin binding properties and histamine H1 blocking activity. It may help to reduce the severity and duration of attacks of paralysis and is effective in rapid onset dystonia-parkinsonism. It is effective in the prophylaxis of migraine, vascular disease, occlusive peripheral, vertigo of central and peripheral origin. It is used as an adjuvant in the therapy of epilepsy. It has been shown to significantly reduce headache frequency and severity in both adults and children. It was discovered at Janssen Pharmaceutica in 1968. It has been listed. Uses: Flunarizine is effective in the prophylaxis of migraine, vascular disease, occlusive peripheral, vertigo of central and peripheral origin. it is used as an adjuvant in the therapy of epilepsy. Synonyms: R-14950; R 14950; R14950; Sibelium; Flunarizinum; Flunarizina; (E)-1-[Bis-(p-fluorophenyl)methyl]-4-cinnamylpiperazine; 1-[Bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propenyl]piperazine; Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)-, (E)-. Grade: 95%. CAS No. 52468-60-7. Molecular formula: C26H26F2N2. Mole weight: 404.50. | |
| Fluorofenidone | Fluorofenidone is a NADPH-oxidase inhibitor. Fluorofenidone Inhibits UUO/IRI-Induced Renal Fibrosis by Reducing Mitochondrial Damage. Fluorofenidone protects liver against inflammation and fibrosis by blocking the activation of NF-κB pathway. Fluorofenidone attenuates paraquat - induced pulmonary fibrosis by regulating the PI3K/Akt/mTOR signaling pathway and autophagy. Fluorofenidone inhibits apoptosis of renal tubular epithelial cells in rats with renal interstitial fibrosis. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 848353-85-5. Molecular formula: C12H10FNO. Mole weight: 203.22. Purity: >98%. IUPACName: 1-(3-Fluorophenyl)-5-methylpyridin-2-one. Canonical SMILES: O=C1C=CC(C)=CN1C2=CC=CC(F)=C2. Product ID: ACM848353855. Alfa Chemistry ISO 9001:2015 Certified. | |
| Fluvastatin Methyl Ester | Fluvastatin Methyl Ester is an indispensable biomedical entity, demonstrating paramount significance in studying dyslipidemia. Through potent inhibition of HMG-CoA reductase, Fluvastatin Methyl Ester remarkably mitigates LDL cholesterol levels. Synonyms: AKOS015896075; AC-4521; (3R,5S,6E)-rel-7-[3-(4-Fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic Acid Methyl Ester; 786710-21-2; Methyl (3R,5S,E)-7-(3-(4-fluorophenyl)-1-isopropyl-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoate. Grade: > 95%. CAS No. 786710-21-2. Molecular formula: C25H28FNO4. Mole weight: 425.50. | |
| fumarate reductase (quinol) | The enzyme, which is found in anaerobic and facultative organisms such as bacteria, parasitic helminthes, and lower marine organisms, utilizes low potential quinols, such as menaquinol and rhodoquinol, to reduce fumarate as the final step of an anaerobic respiratory chain. The enzyme is known as complex II of the electron transfer chain, similarly to EC 1.3.5.1, succinate dehydrogenase (quinone), to which it is closely related. Group: Enzymes. Synonyms: FRD; menaquinol-fumarate oxidoreductase; succinate dehydrogenase (menaquinone); succinate:menaquinone oxidoreductase; fumarate reductase (menaquinone); complex II (ambiguous). Enzyme Commission Number: EC 1.3.5.4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1388; fumarate reductase (quinol); EC 1.3.5.4; FRD; menaquinol-fumarate oxidoreductase; succinate dehydrogenase (menaquinone); succinate:menaquinone oxidoreductase; fumarate reductase (menaquinone); complex II (ambiguous). Cat No: EXWM-1388. | |
| Glutathione (1S, 2R)-Isomer | Glutathione (1S, 2R)-Isomer is a paramount natural antioxidant, assuming a pivotal stance in cellular detoxification. Its profound efficacy lies in safeguarding cells against oxidative stress while concurrently harmonizing cellular redox equilibrium, thereby bolstering the immune system. With multifarious dimensions, Glutathione (1S, 2R)-Isomer proves indispensable in studyting a gamut of maladies encompassing hepatic infirmities, neurodegenerative perturbations, and malignant pathologies. Grade: > 95%. CAS No. 274260-05-8. Molecular formula: C10H17N3O6S. Mole weight: 307.33. | |
| Glutathione Reductase from Human, Recombinant | Glutathione reductase enzyme is a homodimeric enzyme containing 1 FAD molecule and 1 NADPH binding domain per subunit., Both human GR (hGR) and Plasmodium falciparum GR (PfGR) are essential for the survival of the malaria parasite within the human erythrocyte. Thus, this enzyme may be used for studies of candidate anti-malaria reagents. Group: Enzymes. Synonyms: glutathione-disulfide reductase; glutathione reductase; glutathione reductase (NADPH); NADPH-glutathione reductase; GSH reductase; GSSG reductase; NADPH-GSSG reductase; glutathione S-reductase; NADPH:oxidized-glutathione oxidoreductase; EC 1.8.1.7; 9001-48-3; GR. Enzyme Commission Number: EC 1.8.1.7. CAS No. 9001-48-3. GR. Activity: > 10 units/mg protein. Storage: -20°C. Form: buffered aqueous solution; Solution containing 25 mM Tris-HCl, pH 7.4, 1 mM EDTA, and 50% (v/v) glycerol. Source: E. coli. Species: Human. glutathione-disulfide reductase; glutathione reductase; glutathione reductase (NADPH); NADPH-glutathione reductase; GSH reductase; GSSG reductase; NADPH-GSSG reductase; glutathione S-reductase; NADPH:oxidized-glutathione oxidoreductase; EC 1.8.1.7; 9001-48-3; GR. Cat No: NATE-0320. | |
| GNF179 | GNF179 exhibits a low clearance (CL=22 ml/min/kg, ~25% of hepatic blood flow in mice), a large volume of distribution (steady-state volume of distribution, Vss=11.8 l/kg), a moderate residence time (MRT=9 hours) and suitable terminal half-life (t1/2=8.9 hours). GNF179 reduced Plasmodium berghei parasitemia levels by 99.7% with a single 100 mg/kg oral dose, and prolonged mouse survival by an average of 19 days. GNF179 was able to protect against an infectious P. berghei sporozoite challenge with a single oral dose at 15 mg/kg while NITD609 was not. Synonyms: GNF 179; GNF-179. Grade: >98%. CAS No. 1261114-01-5. Molecular formula: C22H23ClFN5O. Mole weight: 427.9. | |
| GNF179 Metabolite | GNF179 exhibits a low clearance (CL=22 ml/min/kg, ~25% of hepatic blood flow in mice), a large volume of distribution (steady-state volume of distribution, Vss=11.8 l/kg), a moderate residence time (MRT=9 hours) and suitable terminal half-life (t1/2=8.9 hours). GNF179 reduced Plasmodium berghei parasitemia levels by 99.7% with a single 100 mg/kg oral dose, and prolonged mouse survival by an average of 19 days. GNF179 was able to protect against an infectious P. berghei sporozoite challenge with a single oral dose at 15 mg/kg while NITD609 was not. Synonyms: GNF 179 Metabolite; GNF-179 Metabolite. Grade: >98%. CAS No. 1310455-86-7. Molecular formula: C14H16FN3. Mole weight: 245.3. | |
| GR24 | (Rac)-GR24 (Strigolactone GR24) is a plant hormone analog. (Rac)-GR24 can mimic the natural germination stimulus of parasitic plant seeds, promoting seed germination in the absence of host plants, thereby reducing the number of parasitic seeds in the soil. (Rac)-GR24 can be used in agricultural research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Strigolactone GR24. CAS No. 76974-79-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-129038. | |
| Isomalt | Isomalt. Synonyms: Hydrogenated isomaltulose; hydrogenated palatinose. CAS No. 64519-82-0. Product ID: PE-0494. Category: Sweetening agent. Product Keywords: Pharmaceutical Excipients; Excipients for Solid Dosage Form; Isomalt; Sweeteners Excipients; Sweetening agent; 64519-82-0; 64519-82-0. UNII: S870P55O2W. Stability and Storage Conditions: Isomalt has very good thermal and chemical stability. When it is melted, no changes in the molecular structure are observed. It exhibits considerable resistance to acids and microbial influences.Isomalt is non-hygroscopic, and at 25°C does not significantly absorb additional water up to a relative humidity (RH) of 85%; paracetamol (acetaminophen) tablets based on isomalt were stored for 6 months at 85% RH at 208C and retained their physical aspect. If stored under normal ambient conditions, isomalt is chemically stable for many years. When it is stored in an unopened container at 20°C and 60% RH, a re-evaluation after 3 years is recommended. Isomalt does not undergo browning reactions; it has no reducing groups, and therefore it does not react with other ingredients in a formulation (e.g. with amines in Maillard reactions). Source and Preparation: Isomalt is produced from food-grade sucrose in a two-stage process.Beet sugar is converted by enzymatic transglucosidation into the reducing disaccharide isomaltulose. This undergoes catalytical hydrogenation to produce isomalt. Safety: Isomal |  |
| (+)-Ketoconazole | (+)-Ketoconazole, an imidazole anti-fungal agent, has often produced features of androgen deficiency including decreased libido, gynecomastia, impotence, oligospermia, and decreased testosterone levels, in men being treated for chronic mycotic infections. (+)-Ketoconazole also is a cytochrome P450 inhibitor. (+)-Ketoconazole (KTZ), on the antischistosomal potential of these quinolines against Schistosoma mansoni infection by evaluating parasitological, histopathological, and biochemical parameters. Mice were classified into 7 groups: uninfected untreated (I), infected untreated (II), infected treated orally with PZQ (1,000 mg/kg) (III), QN (400 mg/kg) (IV), KTZ (10 mg/kg)+QN as group IV (V), HF (400 mg/kg) (VI), and KTZ (as group V)+HF (as group VI) (VII). KTZ plus QN or HF produced more inhibition (P<0.05) in hepatic CYP450 (85.7% and 83.8%) and CYT b5 (75.5% and 73.5%) activities, respectively, than in groups treated with QN or HF alone. This was accompanied with more reduction in female (89.0% and 79.3%), total worms (81.4% and 70.3%), and eggs burden (hepatic; 83.8%, 66.0% and intestinal; 68%, 64.5%), respectively, and encountering the granulomatous reaction to parasite eggs trapped in the liver. Synonyms: Ethanone, 1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]-; 1-(4-(4-(((2R,4S)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4- | |
| Naringin | Naringin. Applications: 1.anti-inflammatory, anti-viral, anti-mutation, anti-carcinogen. 2.hypotensive activity, function as urogastrone, alleviating pain.3.tranquilizing, lowering blood viscosity , reduce the emerge of the thrombus. Group: Others. Synonyms: Naringin; 10236-47-2. CAS No. 10236-47-2. Purity: 98%, HPLC. Mole weight: C27H32O14; 580.53. Appearance: light white powder. Storage: 24 months with original packing under 18°C. Store in cool dry place,avoid sunlight and high temperature. Source: Extracted from the fruit of Citrus paradisi. Naringin; 10236-47-2; plant extract. Pack: 1kg, 5kg, 10kg aluminum foil vacuum bag; or 20kg, 25kg Fiber Drum. Cat No: EXTW-206. | |
| Native Bovine Protein Disulfide Isomerase | Protein Disulfide Isomerase (PDI) has the C-terminal ER retention sequence Lys-Asp-Glu-Leu. It has active, intracellular traffic to different cell compartments. PDI supports internalization of Chlamydia, cholera and diphtheria toxins in some hosts. PDI is required for Sindbis virus infection and aids in reducing HIV gp120 protein thiols. PDI facilitates formation of the correct disulfide bonds by promoting rapid reshuffling of disulfide pairings. Protein disulfide isomerase (pdi) from bovine liver is a homodimer with a molecular weight of 107 kda (gel filtration) and the molecular weight of the monomer has been reported at 57 kda (sds-page). the enzyme is a glycoprotein ... is mainly l ocated in the er, where it assists in protein-folding and thiol-disulfide exchanges. it is used to study functional role of pdi in parasite infection and the interaction between macrophage pdi and l. chagasi. Group: Enzymes. Synonyms: Protein disulfide isomerase; PDI; EC 5.3.4.1; 37318-49-3; S-S rearrangase. Enzyme Commission Number: EC 5.3.4.1. CAS No. 37318-49-3. Purity: >95% (SDS-PAGE). PDI. Activity: 100-400 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing potassium phosphate buffer salts and stabilizer. Source: Bovine liver. Species: Bovine. Protein disulfide isomerase; PDI; EC 5.3.4.1; 37318-49-3; S-S rearrangase. Cat No: NATE-0533. | |
| Native Staphylococcus aureus α-Hemolysin | α-Hemolysin is a 33 kDa extracellular protein secreted by most strains of pathogenic Staphylococcus aureus. It is selectively hemolytic and has a marked preference for rabbit red blood cells. It induces dermonecrosis, spastic muscle paralysis, and it is lethal for laboratory animals. The toxin must be in the monomeric form to initially bind to a membrane and specific receptors are not required for binding. Upon binding to biological membranes and/or artificial membranes, self-oligomerization occurs, resulting in ring structures (hexameric aggregates) believed to represent transmembrane pores, which are permeable to ions and small metabolites. Group: Enzymes. Synonyms: α-Hemolysin; 94716-94-6; α-Toxin. α-Hemolysin. Activity: > 10,000 units/mg protein. Storage: 2-8°C. Source: Staphylococcus aureus. α-Hemolysin; 94716-94-6; α-Toxin. Cat No: NATE-0753. | |
| nitrite reductase (NO-forming) | The reaction is catalysed by two types of enzymes, found in the perimplasm of denitrifying bacteria. One type comprises proteins containing multiple copper centres, the other a heme protein, cytochrome cd1. Acceptors include c-type cytochromes such as cytochrome c-550 or cytochrome c-551 from Paracoccus denitrificans or Pseudomonas aeruginosa, and small blue copper proteins such as azurin and pseudoazurin. Cytochrome cd1 also has oxidase and hydroxylamine reductase activities. May also catalyse the reaction of hydroxylamine reductase (EC 1.7.99.1) since this is a well-known activity of cytochrome cd1. Group: Enzymes. Synonyms: cd-cytochrome nitrite reductase; [nitrite reductase (cytochrome)] [misleading, see comments.]; cytochrome c-551:O2, NO2+ oxidoreductase; cytochrome cd; cytochrome cd1; hydroxylamine. Enzyme Commission Number: EC 1.7.2.1. CAS No. 9080-3-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1616; nitrite reductase (NO-forming); EC 1.7.2.1; 9080-03-9; cd-cytochrome nitrite reductase; [nitrite reductase (cytochrome)] [misleading, see comments.]; cytochrome c-551:O2, NO2+ oxidoreductase; cytochrome cd; cytochrome cd1; hydroxylamine (acceptor) reductase; methyl viologen-nitrite reductase; nitrite reductase (cytochrome; NO-forming). Cat No: EXWM-1616. | |
| nitrous-oxide reductase | The reaction is observed only in the direction of nitrous oxide reduction. Contains the mixed-valent dinuclear CuA species at the electron entry site of the enzyme, and the tetranuclear Cu-Z centre in the active site.In Paracoccus pantotrophus, the electron donor is cytochrome c552. Group: Enzymes. Synonyms: nitrous oxide reductase; N2O reductase; nitrogen:(acceptor) oxidoreductase (N2O-forming). Enzyme Commission Number: EC 1.7.2.4. CAS No. 55576-44-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1619; nitrous-oxide reductase; EC 1.7.2.4; 55576-44-8; nitrous oxide reductase; N2O reductase; nitrogen:(acceptor) oxidoreductase (N2O-forming). Cat No: EXWM-1619. | |
| Pararosaniline chloride certified | Pararosaniline chloride certified. Group: Biochemicals. Alternative Names: Basic parafuchsin; Basic red 9; CI 425. Grades: Highly Purified. CAS No. 569-61-9. Pack Sizes: 500g, 1kg, 2kg, 5kg. US Biological Life Sciences. | Worldwide |
| Pararosaniline hydrochloride | Pararosaniline hydrochloride (Basic red 9) is a pH-responsive basic dye, as a biological stain to track certain proteins. The pH of the acidified Pararosaniline hydrochloride reagent has a significant effect on the color and the maximum absorption wavelength (λmax) of the reaction system, with its optimum pH 0.48 and a λmax at 549?nm. Pararosaniline hydrochloride is also a strong modifier of RNA splicing. Pararosaniline hydrochloride has been used in the analysis of SO 2 and formaldehyde and staining of bacteria or other organisms. Pararosaniline hydrochloride is extensively used in industries like textile, printing, paper, cosmetic, and leather [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Basic red 9. CAS No. 569-61-9. Pack Sizes: 10 g; 25 g. Product ID: HY-W127770. | |
| Phosphonomycin Calcium salt | It is produced by the strain of Str. fradiae NRRL-3417, Str. viridchromogenes NRRL-3413. It's an antibiotic that contains phosphorus. It has anti-gram positive bacterial and negative bacterial activity, inorganic phosphorus and sodium chloride can reduce its activity. It has protective effect on mice infected with Staphylococcus aureus, Salmonella typhi and Salmonella paratyphi B by oral administration. Synonyms: (-)-Phosphonomycin Calcium salt; Calcium fosfomycin; fosfomycin calcium; Fosmicin; Phosphonic acid, [(2R,3S)-3-methyloxiranyl]-, calcium salt (1:1); Phosphonic acid, (1,2-epoxypropyl)-, calcium salt (1:1), (1R,2S)-(-)-; Phosphonic acid, P-[(2R,3S)-3-methyl-2-oxiranyl]-, calcium salt (1:1); Phosphonic acid, (3-methyloxiranyl)-, calcium salt (1:1), (2R-cis)-. Grade: 98%. CAS No. 26016-98-8. Molecular formula: C3H5O4P.Ca. Mole weight: 176.12. | |
| Potassium Alginate | Potassium alginate occurs as a white to yellowish, fibrous or granular powder; it is almost odorless and tasteless. Synonyms: Alginic acid, potassium salt; E402; Improved Kelmar; potassium polymannuronate. CAS No. 9005-36-1. Product ID: PE-0563. Molecular formula: (C6H7O6K)n. Category: Emulsifying Agents; Stabilizing Agents; Suspending Agents; Thickening Agents. Product Keywords: Stabilizers; Emulsifier Excipients; Suspending Agents; ; PE-0563; Potassium Alginate; Emulsifying Agents; Stabilizing Agents; Suspending Agents; Thickening Agents; (C6H7O6K)n; 9005-36-1. UNII: 44ZPJ5W2J1. Chemical Name: Potassium alginate. Grade: Pharmceutical Excipients. Stability and Storage Conditions: In the solid state, potassium alginate is a stable material that is not prone to microbial spoilage. Over time, a slow reduction in the degree of polymerization can occur, which may be reflected in a reduction in the viscosity of solutions. As both temperature and moisture can impair the performance of potassium alginate, storage below 25°C is recommended. Potassium alginate solutions are stable at pH 4-10; long-term storage outside this range can result in depolymerization of the polymer through hydrolysis. Gelation or precipitation of the alginate can occur at pH values less than 4. Liquid or semisolid alginate formulations should be preserved: suitable preservatives are sodium benzoate, potassium sorbate, or parabens. Potassium algin | |
| Proguanil hydrochloride | Proguanil hydrochloride, an antimalarial prodrug, is metabolized to the active metabolite Cycloguanil (HY-12784). Proguanil hydrochloride is a dihydrofolate reductase (DHFR) inhibitor. Uses: Proguanil (chlorguanide) may be used in anti-parasitic protozoan drug development to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an antimalarial drug. Additional or Alternative Names: Chlorguanide, N1-(4-Chlorophenyl)-N5-isopropylbiguanide, Proguanil hydrochloride. Product Category: Solvents. CAS No. 637-32-1. Molecular formula: C11H17Cl2N5. Mole weight: 290.19. IUPACName: hydrogen 1-({amino[(4-chlorophenyl)amino]methylidene}amino)-N'-(propan-2-yl)methanimidamide chloride. Canonical SMILES: [H+].[Cl-].CC(C)N=C(N)N=C(N)NC1=CC=C(Cl)C=C1. ECNumber: 211-283-7. Product ID: ACM637321. Alfa Chemistry ISO 9001:2015 Certified. | |
| Propylparaben | Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods. Propylparaben disrupts follicular growth and steroidogenic function by altering cell cycle, apoptosis and steroidogenic pathways. Propylparaben also reduced sperm count and motility in rats [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: Propyl parahydroxybenzoate; Propyl 4-hydroxybenzoate. CAS No. 94-13-3. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-N2026. | |
| Propylparaben (Standard) | Propylparaben (Standard) is the analytical standard of Propylparaben. This product is intended for research and analytical applications. Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods. Propylparaben disrupts follicular growth and steroidogenic function by altering cell cycle, apoptosis and steroidogenic pathways. Propylparaben also reduced sperm count and motility in rats [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. CAS No. 94-13-3. Pack Sizes: 50 mg; 100 mg; 250 mg. Product ID: HY-N2026R. | |
| Pyrimethamine | Pyrimethamine (Pirimecidan) is a potent, orally active dihydrofolate reductase (DHFR) inhibitor. Pyrimethamine is an antimalarial agent. Pyrimethamine affects the nucleoprotein metabolism of malarial parasites by interference in the folic - folinic acid systems and affects cell division by inhibiting the conversion of dihydrofolate to tetrahydrofolate [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pirimecidan; Pirimetamin; RP 4753. CAS No. 58-14-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-18062. | |
| Sinapinic acid | Sinapinic acid (Sinapic acid) is a phenolic compound isolated from Hydnophytum formicarum Jack. Rhizome, acts as an inhibitor of HDAC , with an IC 50 of 2.27 mM [1] , and also inhibits ACE-I activity [2]. Sinapinic acid posssess potent anti-tumor activity, induces apoptosis of tumor cells [1]. Sinapinic acid shows antioxidant and antidiabetic activities [2]. Sinapinic acid reduces total cholesterol, triglyceride, and HOMA-IR index, and also normalizes some serum parameters of antioxidative abilities and oxidative damage in ovariectomized rats [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Sinapic acid. CAS No. 530-59-6. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-W009732. | |
| Sodium 4-aminosalicylate dihydrate | Sodium 4-aminosalicylate (Sodium para-Aminosalicylic acid) dihydrate is para-aminosalicylic acid (PAS), a dihydrofolate reductase ( DHFR ) inhibitor and antituberculous agent. PAS is incorporated into the folate pathway via dihydropteroate synthase (DHPS) and dihydrofolate synthase (DHFS) to generate the hydroxydihydrofolate antimetabolite, which in turn inhibits DHFR enzyme activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4-Aminosalicylic acid sodium salt dihydrate. CAS No. 6018-19-5. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-I0447A. | |
| Sodium Citrate Buffer, 0.1M, pH 4.0 | Sodium Citrate Buffer, 0.1M, pH 4.0 is a commonly used buffer. Sodium Citrate Buffer, 0.1M, pH 4.0 resists pH fluctuations, chelates metal ions, and regulates the redox potential of the system. Sodium Citrate Buffer, 0.1M, pH 4.0 is used in heat-induced epitope retrieval (HIER) to reverse the loss of antigenicity of certain epitopes in formalin-fixed paraffin-embedded tissues. Sodium Citrate Buffer, 0.1M, pH 4.0 is the preferred solution for most antibodies. Sodium citrate buffer, 0.1M, pH 4.0 can be used for hydration of liposome membranes[1][2][3]. Uses: Scientific research. Group: Biochemical assay reagents. Pack Sizes: 80 mL; 100 mL; 200 mL. Product ID: HY-B1610N. | |
| Sudan R | Sudan dyes and para red in food. Group: Biochemicals. Alternative Names: 1-[2- (2-Methoxyphenyl) diazenyl]-2-naphthalenol. Grades: Highly Purified. CAS No. 1229-55-6. Pack Sizes: 250g, 500g, 1kg, 2kg, 5kg. US Biological Life Sciences. | Worldwide |
| Sudan Red 7B (Solvent Red 19) 98+% | Sudan dyes and para red in food. Group: Biochemicals. Alternative Names: Solvent Red 19; CI 265. Grades: Reagent Grade. CAS No. 6368-72-5. Pack Sizes: 25g, 100g, 250g. US Biological Life Sciences. | Worldwide |
| Tenapanor | Tenapanor (AZD1722) is a potent and orally active sodium/hydrogen exchanger isoform 3 (NHE3) inhibitor. Tenapanor reduces intestinal phosphate absorption predominantly through reduction of passive paracellular phosphate flux. Tenapanor has the potential for the research of hyperphosphatemia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD1722; RDX5791. CAS No. 1234423-95-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15991. | |
| Tenapanor hydrochloride | Tenapanor (AZD1722) hydrochloride is a potent and orally active sodium/hydrogen exchanger isoform 3 (NHE3) inhibitor. Tenapanor hydrochloride reduces intestinal phosphate absorption predominantly through reduction of passive paracellular phosphate flux. Tenapanor hydrochloride has the potential for the research of hyperphosphatemia [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD1722 hydrochloride; RDX5791 hydrochloride. CAS No. 1234365-97-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15991A. | |
| trypanothione-disulfide reductase | Trypanothione disulfide is the oxidized form of N1,N8-bis(glutathionyl)-spermidine from the insect-parasitic trypanosomatid Crithidia fasciculata. The enzyme from Crithidia fasciculata is a flavoprotein (FAD), whose activity is dependent on a redox-active cystine at the active centre. (cf. EC 1.8.1.7, glutathione-disulfide reductase). Group: Enzymes. Synonyms: trypanothione reductase; NADPH2:trypanothione oxidoreductase. Enzyme Commission Number: EC 1.8.1.12. CAS No. 102210-35-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1638; trypanothione-disulfide reductase; EC 1.8.1.12; 102210-35-5; trypanothione reductase; NADPH2:trypanothione oxidoreductase. Cat No: EXWM-1638. | |
| Vat Orange 1 | Vat Orange 1. Group: Biochemicals. Alternative Names: Dibromodibenzochrysene-7,14-dione; Ahcovat Golden Yellow RK; Benzadone Gold Yellow RK; C.I. 59105; C.I. Pigment Orange 77; C.I. Vat Orange 23; Carbanthrene Golden Yellow RK; Cibanone Golden Yellow FRK; Cibanone Golden Yellow RK; Helanthrene Yellow RK; Hostavat Golden Yellow RK; Indanthren Golden Yellow RK; Indanthrene Golden Orange BBG; Indanthrene Golden Yellow RK; Mikethren Gold Yellow RK; Nihonthrene Golden Yellow RK; Nyanthrene Golden Yellow RK; Palanthrene Golden Yellow RK; Paradone Golden Yellow RK; Pigment Orange 77; Ponsol Golden Orange 2BG; Romantrene Golden Yellow FRK; Sandothrene Golden Yellow NRK; Solanthrene Brilliant Yellow R; Symuler Fast Red NRK; Threne gold yellow RK; Tinon Golden Yellow RK; Vat Golden Yellow KKh; Vat Golden Yellow KKh 10; Vat Golden Yellow KKhP; Vat Golden Yellow RK. Grades: Highly Purified. CAS No. 1324-11-4. Pack Sizes: 100mg. Molecular Formula: C24H10Br2O2, Molecular Weight: 490.14. US Biological Life Sciences. | Worldwide |
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