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| Product | Description | |
|---|---|---|
| PIT 1 | PIT 1. Group: Biochemicals. Grades: Purified. CAS No. 53501-41-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| PIT 1 | PIT 1 is an apoptosis inducing selective PIP3 antagonist which has been shown to inhibit the binding of PIP3 to the pleckstrin homology (PH) domain of Akt (IC50 = 31.03 μM). PIT 1 inhibits cancer cell survival and induces apoptosis by inhibition of PIP3-dependent PI 3-kinase/Akt signaling, and exhibits antitumor activity in vivo. Synonyms: Pit-1; Pit 1; Pit1. N-[[ (3-Chloro-2-hydroxy-5-nitrophenyl) amino]thioxomethyl]benzamide. Grades: ≥99% by HPLC. CAS No. 53501-41-0. Molecular formula: C14H10ClN3O4S. Mole weight: 351.76. |  |
| PIP3 Antagonist II, DM-PIT-1, N- ( (2-Hydroxy-5-nitrophenyl) carbamothioyl) -3, 5-dimethylbenzamide, N- ( ( (2-Hydroxy-5-nitrophenyl) amino) thioxomethyl) -3, 5-dimethyl-benzamide, Akt Inhibitor XXII, PDK1 Inhibitor VI) | A cell-permeable benzoylthiourea compound that is shown to compete against PIP3 for binding PH domains of Akt1 (IC50 >31uM), ARNO, GRP1, and P1. Effectively blocks PIP3-dependent cellular PI3K-PDK1-Akt signaling pathway activation in U87MG (25 to 100uM for 3d) and PDGF-induced Akt and GRP membrane translocation in serum-starved SUM159 cells (1h 100uM pretreatment), while being inactive against PDGF-induced Btk translocation or PMA-induced PLC-delta and TAPP1/2 translocations. Although DM-PIT-1 can be administered as a DMSO stock for effective culture treatments, incorporating DM-PIT-1 into PEG-PE mixed micelles enhances its solubility (up to 1mM) and i.v. dosing limit for more effective in vivo administrations (5% vs. 41% of control 4T1 tumor size in mice via 1mg/kg micelles-formulated or 0.4mg/kg free drug daily i.v., respectively). Group: Biochemicals. Grades: Highly Purified. CAS No. 701947-53-7. Pack Sizes: 25mg. Molecular Formula: C??H??N?O?S, Molecular Weight: 345.4. US Biological Life Sciences. | Worldwide |
| PIT-1 | PIT-1 is a selective PIP3 (phosphatidylinositol 3,4,5-trisphosphate) antagonist. PIT-1 inhibits cancer cell survival and induces apoptosis by inhibition of PIP3 dependent PI3K / Akt signaling. PIT-1 exhibits antitumor activity in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 53501-41-0. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103224. |  |
| Pitavastatin 1-Phenylethylamide | Pitavastatin 1-Phenylethylamide is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin Impurity. Molecular formula: C33H33FN2O3. Mole weight: 524.62. | |
| Pitavastatin Impurity 10 | An impurity of Pitavastatin which has a potent cholesterol-lowering action. Grades: > 95%. Molecular formula: C13H22O5. Mole weight: 258.32. | |
| Pitavastatin Impurity 10 | Pitavastatin Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-4-hydroxytetrahydro-2H-pyran-2-one. CAS No. 141750-63-2. Molecular formula: C25H22FNO3. Mole weight: 403.45. Catalog: APB141750632. |  |
| Pitavastatin Impurity 11 | An impurity of Pitavastatin which is a chemically synthesized statin used for hypercholesterolaemia (elevated cholesterol) and for the prevention of cardiovascular disease. Grades: > 95%. Molecular formula: C33H33FN2O3. Mole weight: 524.64. | |
| Pitavastatin Impurity 12 | An impurity of Pitavastatin which is a relatively newly developed cholesterol lowering agent used to lower high cholesterol and triglycerides in certain patients. Grades: > 95%. Molecular formula: C27H28FNO4.C8H11N. Mole weight: 570.71. | |
| Pitavastatin Impurity 13 | Pitavastatin Impurity 13 (Pitavastatin 2,4,6-Triene Impurity) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin 2,4,6-Triene Impurity. Grades: > 95%. CAS No. 2086271-67-0. Molecular formula: C25H20FNO2. Mole weight: 385.43. | |
| Pitavastatin Impurity 14 | Pitavastatin Impurity 14 (Pitavastatin 2-Fluoro Isomer) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin 2-Fluoro Isomer. Grades: > 95%. Molecular formula: C25H24FNO4. Mole weight: 421.46. | |
| Pitavastatin Impurity 15 | Pitavastatin Impurity 15 (Pitavastatin 4,6-Diene Impurity) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (3S,4E,6E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3-hydroxyhepta-4,6-dienoic acid; Pitavastatin 4,6-Diene Impurity. Molecular formula: C25H22FNO3. Mole weight: 403.44. | |
| Pitavastatin Impurity 16 | Pitavastatin Impurity 16 (Pitavastatin 4-Desfluoro 4-Hydroxy Impurity) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin 4-Desfluoro 4-Hydroxy Impurity. Grades: > 95%. Molecular formula: C25H25NO5. Mole weight: 419.47. | |
| Pitavastatin Impurity 18 | An impurity of Pitavastatin which lowers both total cholesterol and low density lipoprotein cholesterol in animals and humans. Synonyms: Pitavastatin N-Oxide. Grades: > 95%. Molecular formula: C25H24FNO5. Mole weight: 437.47. | |
| Pitavastatin Impurity 18 Sodium Salt | Pitavastatin Impurity 18 Sodium Salt (Pitavastatin N-Oxide Sodium Salt) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-1-oxido-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid, sodium salt (1:1); Pitavastatin N-Oxide Sodium Salt. CAS No. 2276678-27-2. Molecular formula: C25H23FNO5Na. Mole weight: 459.44. | |
| Pitavastatin Impurity 19 | An impurity of Pitavastatin which causes atherosclerosis regression in humans with subclinical carotid atherosclerosis. Synonyms: Pitavastatin Epoxide Impurity. Grades: > 95%. Molecular formula: C25H24FNO5. Mole weight: 437.47. | |
| Pitavastatin Impurity 19 Sodium Salt (Mixture of Diastereomers) | Pitavastatin Impurity 19 Sodium Salt (Mixture of Diastereomers) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (3R,5S)-5-(3-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)oxiran-2-yl)--dihydroxyhept-6-enoic acid. Molecular formula: C25H23FNO5Na. Mole weight: 459.44. | |
| Pitavastatin Impurity 1 Calcium Salt | Pitavastatin Impurity 1 Calcium Salt is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.49. | |
| Pitavastatin Impurity 1 (PP-1) | An impurity of Pitavastatin which is a Hydroxymethylglutaryl-CoA reductase inhibitor. Grades: > 95%. Molecular formula: C25H24FNO4. Mole weight: 421.47. | |
| Rosuvastatin Impurity 61 (Pitavastatin Impurity 64) | Rosuvastatin Impurity 61 (Pitavastatin Impurity 64). Uses: For analytical and research use. Group: Impurity standards. CAS No. 124752-23-4. Molecular formula: C13H22O5. Mole weight: 258.31. Catalog: APB124752234. | |
| 2-Amino-2'-fluorobenzophenone | 2-Amino-2'-fluorobenzophenone is an intermediate in the preparation of the anticholesteremic Pitavastatin. Group: Biochemicals. Grades: Highly Purified. CAS No. 1581-13-1. Pack Sizes: 100mg, 1g. Molecular Formula: C13H10FNO, Molecular Weight: 215.22. US Biological Life Sciences. | Worldwide |
| 2-Amino-2'-fluorobenzophenone | An intermediate in the synthesis of Pitavastatin, a HMG-CoA reductase inhibitor that lowers LDL cholesterol and triglycerides and increase HDL cholesterol in your blood. Synonyms: 2-Amino-2'-fluoro-benzophenone; (2-Amino-phenyl)-(2-fluoro-phenyl)-methanone. Grades: ≥ 95%. CAS No. 1581-13-1. Molecular formula: C13H10FNO. Mole weight: 215.22. | |
| 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinoline-d5 3-Aldehyde | Pitavastatin intermediate. Group: Biochemicals. Alternative Names: 4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-aldehyde-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol | Pitavastatin intermediate. Group: Biochemicals. Alternative Names: 2-Cyclopropyl-4-(4'-fluorophenyl) Quinolyl-3-methanol. Grades: Highly Purified. CAS No. 121660-11-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol-d5 | Pitavastatin intermediate. Group: Biochemicals. Alternative Names: 2-Cyclopropyl-4-(4'-fluorophenyl) Quinolyl-3-methanol-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| [ [2-Cyclopropyl-4- (4-fluorophenyl) -3-quinolinyl] methyl] triphenyl-phosphonium Bromide | [ [2-Cyclopropyl-4- (4-fluorophenyl) -3-quinolinyl] methyl] triphenyl-phosphonium Bromide is an impurity from the synthesis of HMG-CoA reductase inhibitor Pitavastatin [P531040, (Z)-Pitavastatin Calcium Salt]. Group: Biochemicals. Grades: Highly Purified. CAS No. 154057-58-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C37H30BrFNP. US Biological Life Sciences. | Worldwide |
| 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester | 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester is an impurity of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 868536-53-2. Pack Sizes: 50mg, 500mg. Molecular Formula: C20H17NO2. US Biological Life Sciences. | Worldwide |
| (2-Cyclopropyl-4-phenylquinolin-3-yl)methanol | (2-Cyclopropyl-4-phenylquinolin-3-yl)methanol is an impurity of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 250mg. Molecular Formula: C19H17NO. US Biological Life Sciences. | Worldwide |
| 2-Cyclopropyl-4-phenylquinoline-3-carbaldehyde | 2-Cyclopropyl-4-phenylquinoline-3-carbaldehyde is an impurity of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C19H15NO. US Biological Life Sciences. | Worldwide |
| 3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline | 3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline is used to prepare artificial HMG-CoA reductase inhibitors. It is also used to synthesize pitavastatin calcium via stereoselective Wittig olefination reaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 154057-56-4. Pack Sizes: 100mg, 500mg. Molecular Formula: C19H15BrFN. US Biological Life Sciences. | Worldwide |
| 3-Cyclopropyl-3-oxopropanoic Acid Methyl Ester | A reagent used in the synthesis of Pitavastatin. Group: Biochemicals. Alternative Names: Methyl 3-Cyclopropyl-3-oxopropionate; Methyl 2- (Cyclopropylcarbonyl) acetate; β-Oxo-cyclopropanepropanoic Acid Methyl Ester. Grades: Highly Purified. CAS No. 32249-35-7. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| (3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt | (3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt. Group: Biochemicals. Alternative Names: Defluoro Pitavastatin. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C25H24NNaO4 , Molecular Weight: 425.45. US Biological Life Sciences. | Worldwide |
| (3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid tert-Butyl Ester | (3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid tert-Butyl Ester is an intermediate in the synthesis of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: (3R,5S,E)-Tert-butyl 7-(2-cyclopropyl-4-phenylquinolin-3-yl)-3,5-dihydroxyhept-6-enoate; Pitavastatin Impurity compound C; 2-Methyl-2-propanyl (3R,5S,6E)-7-(2-cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoate; 6-Heptenoic acid, 7-(2-cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-. Grades: 97%. Molecular formula: C29H33NO4. Mole weight: 459.58. | |
| (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt | (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Group: Biochemicals. Alternative Names: ent-NK-104; Pitavastatin 3S,5R-Isomer Calcium Salt. Grades: Highly Purified. CAS No. 254452-88-5. Pack Sizes: 2.5mg. Molecular Formula: C25H24FNO4 1/2Ca, Molecular Weight: 440.49. US Biological Life Sciences. | Worldwide |
| (3S,5R)-Pitavastatin Calcium | A metabolite of Pitavastatin which is a potent inhibitor of HMG-CoA reductase (Ki = 1.7 nM). Synonyms: ent-NK-104; Pitavastatin 3S,5R-Isomer Calcium Salt; (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Grades: > 95%. CAS No. 254452-88-5. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.86. | |
| (3S,5S)-Pitavastatin Calcium Salt | A metabolite of Pitavastatin which has a potent cholesterol-lowering action. Synonyms: 3-Epi-NK-104; Pitavastatin 3S,5S-Isomer Calcium Salt; (3S,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Grades: > 95%. CAS No. 254452-92-1. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.5. | |
| 4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic Acid Methyl Ester | 4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic Acid Methyl Ester is an intermediate of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylic Acid Methyl Ester; Methyl 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylate; Methyl 4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinecarboxylate; 3-Quinolinecarboxylic acid, 2-cyclopropyl-4-(4-fluorophenyl)-, methyl este; Pitavastatin Impurity 32. Grades: ≥95%. CAS No. 121659-86-7. Molecular formula: C20H16FNO2. Mole weight: 321.34. | |
| 4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic Acid Methyl Ester | Pitavastatin intermediate. Group: Biochemicals. Alternative Names: 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylic Acid Methyl Ester; Methyl 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylate. Grades: Highly Purified. CAS No. 121659-86-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 4-Dehydroxy-3-dehydro-pitavastatin-d5 Lactone | A labeled metabolite of Pitavastatin in humans and monkeys. Group: Biochemicals. Alternative Names: (6S) -6- [ (1E) -2- [2-Cyclopropyl-d5-4- (4-fluorophenyl) -3-quinolinyl] ethenyl] tetrahydro-2H-pyran-2-one. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 5,6-Epoxyeicosatrienoic acid | 5,6-Epoxyeicosatrienoic acid (5,6-EET; (±)5,6-EpETrE) is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5,6-Epoxyeicosatrienoic acid degrades into 5,6-DiHET and 5,6-δ-lactone, which can be converted to 5,6-DiHET and quantified by GC-MS. In neuroendocrine cells, such as the anterior pituitary and pancreatic islets, 5,6-Epoxyeicosatrienoic acid has been implicated in the mobilization of calcium and hormone secretion. 5,6-Epoxyeicosatrienoic acid is an inhibitor of T-type voltage-gated calcium channels (Cav3) that inhibits isoforms Cav3.1, Cav3.2 ( IC 50 =0.54 μM), and Cav3. and decreases nifedipine-resistant phenylephrine-induced vasoconstriction in isolated mouse mesenteric arteries via Cav3.2 blockade when used at a concentration of 3 μM. In addition, it is a substrate of COX-1 and COX-2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5,6-EET; (±)5,6-EpETrE. CAS No. 87173-80-6. Pack Sizes: 25 μg (312.04 μM * 250 μL in Ethanol); 50 μg (312.04 μM * 500 μL in Ethanol); 100 μg (312.04 μM * 1 mL in Ethanol). Product ID: HY-132184. | |
| 6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine | 6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine is one of Pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: 9-cyclopropyl-15-fluoro-8-azatetracyclo; Pitavastatin Impurity 3 (PP-3). Grades: 98%. CAS No. 1187966-94-4. Molecular formula: C20H16FN. Mole weight: 289.35. | |
| 6-Cyclopropyl-10-fluorobenzo[k]phenanthridine | 6-Cyclopropyl-10-fluorobenzo[k]phenanthridine is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin Impurity 4 (PP-4). Grades: 98%. CAS No. 1187966-95-5. Molecular formula: C20H14FN. Mole weight: 287.33. | |
| (6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-5,6-dihydro-2H-pyran-2-one | (6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-5,6-dihydro-2H-pyran-2-one is an impurity in the production of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: (S)-6-{(E)-2-[2-Cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-vinyl}-5,6-dihydro-pyran-2-one; Pitavastatin Impurity 29; (S,E)-6-(2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-5,6-dihydro-2H-pyran-2-one; 2H-Pyran-2-one, 6-((1E)-2-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl)ethenyl)-5,6-dihydro-, (6S)-; 2H-Pyran-2-one, 6-(2-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl)ethenyl)-5,6-dihydro-, (S-(E))-. Grades: ≥95%. CAS No. 148516-15-8. Molecular formula: C25H20FNO2. Mole weight: 385.43. | |
| 7-?[2-?cyclopropyl-?4-? (4-?fluorophenyl) ?-?3-?quinolinyl]?-?3, ?5-?dihydroxy-6-?Heptenoic acid | An isomer of Pitavastatin. Pitavastatin is a potent HMG-CoA reductase inhibitor. CAS No. 121659-03-8. Molecular formula: C25H24FNO4. Mole weight: 421.468. | |
| Abarelix | Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Synonyms: Plenaxis, PPI-149; PPI 149; PPI149; R-3827; R 3827; R3827. Grades: 98%. CAS No. 183552-38-7. Molecular formula: C72H95ClN14O14. Mole weight: 1416.09. | |
| Ac-Asp(5)-AVP | Ac-Asp(5)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Ac-Asp(5)-Vasopressin; N-Ac-Asp(5)-AVP; [Cys(Ac)1-Asp(5)]-Argipressin; Ac-Cys-Tyr-Phe-Gln-Asp-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Acetyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 2594426-06-7. Molecular formula: C48H66N14O14S2. Mole weight: 1127.26. | |
| Ac-AVP | Ac-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Vasopressin, N-acetyl-8-L-arginine-; Vasopressin, 1-(N-acetyl-L-cysteine)-8-arginine; Vasopressin, 8-acetylarginine; 1-Acetylcysteine-8-arginine-vasopressin; N-Acetyl-Vasopressin; N-acetyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide; Ac-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Ac-Vasopressin; N-Acetyl-8-L-argininevasopressin. CAS No. 38106-69-3. Molecular formula: C48H67N15O13S2. Mole weight: 1126.28. | |
| Acetyl PACAP (1-38) (human, mouse, ovine, porcine, rat) trifluoroacetate salt | Acetyl pituitary adenylate cyclase-activating peptide (PACAP) (1-38) is an N-terminally acetylated form of PACAP (1-38). Synonyms: Acetyl pituitary adenylate cyclase-activating peptide (1-38). Grades: ≥95%. Molecular formula: C205H333N63O54S·xCF3COOH. Mole weight: 4576.29. | |
| ACTH (1-10), human | Adrenocorticotropic hormone (ACTH) (1-10) is an N-terminal peptide fragment of ACTH, a peptide hormone produced by the anterior pituitary gland that is involved in the biological stress response. Synonyms: H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-OH; L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycine; ACTH (1-10) (human, mouse, rat, porcine, bovine, ovine); Adrenocorticotropic Hormone (1-10); Corticotropin (1-10); Adrenocorticotropic Hormone (ACTH) (1-10), human. Grades: ≥97% by HPLC. CAS No. 2791-5-1. Molecular formula: C59H78N16O16S. Mole weight: 1299.41. | |
| ACTH 1-17 | ACTH (1-17) is a peptide fragment of ACTH, a tropic hormone produced by the anterior pituitary. Synonyms: Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg; Alpha1-17-ACTH; a1-17-Corticotropin; L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycyl-L-lysyl-L-prolyl-L-valyl-glycyl-L-lysyl-L-lysyl-L-arginine; 1-Ala-17-Lys-ACTH 4-amino-n-butylamide; 1-beta-Alanine-17-(L-2,6-diamino-N-(4-aminobutyl)hexanamide)-alpha1-17-corticotrophin; alsactide; Synchrodyn; Adrenocorticotropic Hormone Fragment 1-17 human, rat. Grades: 98%. CAS No. 7266-47-9. Molecular formula: C95H145N29O23S. Mole weight: 2093.41. | |
| ACTH (1-17) TFA | ACTH (1-17) TFA is a peptide fragment of ACTH, a tropic hormone produced by the anterior pituitary. Synonyms: α1-17-ACTH (TFA); L-Seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginine.TFA; a1-17-Corticotropin.TFA; acth(1-17).TFA,human; Adrenocorticotropic Hormone Fragment 1-17.TFA human, rat; Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg.TFA. Grades: ≥98%. Molecular formula: C95H145N29O23S.C2HF3O2. Mole weight: 2207.43. | |
| ACTH (1-39) (Human) | Potent endogenous melanocortin receptor 2 (MC2) agonist (EC50 = 57 pM). Component of the hypothalamic-pituitary-adrenal (HPA) axis that stimulates glucocorticoid production and release from the adrenal cortex. Induces insulin resistance, promotes a proinflammatory profile and stimulates UCP-1 in adipocytes in vitro. Group: Biochemicals. Alternative Names: Adrenocorticotropic hormone (1-39); Adrenocorticotropin; Corticotropin. Grades: Highly Purified. CAS No. 12279-41-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| ACTH (1-39), Porcine | ACTH (1-39) is a potent agonist of melanocortin receptor 2 (MC2R) with an EC50 value of 57 pM in HeLa cells expressing the mouse receptor. Synonyms: Adrenocorticotropic Hormone from porcine pituitary; Adrenocorticotropic Hormone Fragment 1-39; Corticotropin A. Grades: 95%. CAS No. 9061-27-2. Molecular formula: C210H314N56O57S. Mole weight: 4567.15. | |
| ACTH (18-39) (human) | ACTH (18-39) (human) is a C-terminal peptide fragment of ACTH, a tropic hormone produced by the anterior pituitary. Synonyms: Adrenocorticotropic Hormone (ACTH) (18-39), human; H-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH; L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-prolyl-L-asparagyl-glycyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-prolyl-L-leucyl-L-alpha-glutamyl-L-phenylalanine; Adrenocorticotropic Hormone Fragment 18-39 human; CLIP. Grades: ≥95%. CAS No. 53917-42-3. Molecular formula: C112H165N27O36. Mole weight: 2465.67. | |
| ACTH (18-39), human TFA | ACTH (18-39) (human) is a C-terminal peptide fragment of ACTH, a tropic hormone produced by the anterior pituitary. Synonyms: Adrenocorticotropic Hormone (ACTH) (18-39), human TFA; CLIP (human) (TFA); Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe.TFA; L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-prolyl-L-asparagyl-glycyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-prolyl-L-leucyl-L-alpha-glutamyl-L-phenylalanine.TFA. Grades: >98%. CAS No. 73724-75-1. Molecular formula: C112H165N27O36.C2HF3O2. Mole weight: 2579.69. | |
| ACTH 22-39 | ACTH (22-39) is a peptide fragment of ACTH, a tropic hormone produced by the anterior pituitary. Synonyms: Adrenocorticoptropic Hormone Fragment 22-39; ACTH (22-39) (human); H-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH; L-valyl-L-tyrosyl-L-prolyl-L-asparagyl-glycyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-prolyl-L-leucyl-L-alpha-glutamyl-L-phenylalanine; beta-Cell-Tropin. Grades: ≥95% by HPLC. CAS No. 37548-29-1. Molecular formula: C90H125N19O32. Mole weight: 1985.06. | |
| Adrenocorticotropic hormone | Adrenocorticotropic hormone (ACTH) is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone regulates cortisol and androgen production [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: ACTH; Adrenocorticotrophic hormone. CAS No. 9002-60-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-106373. | |
| Adrenocorticotropic Hormone (ACTH) (18-39), human TFA | Adrenocorticotropic Hormone (ACTH) (18-39), human TFA is a corticotropinlike intermediate lobe peptide, which is is produced in the melanotrophs of the intermediate lobe of the pituitary [1]. Uses: Scientific research. Group: Peptides. Alternative Names: CLIP (human) TFA. CAS No. 73724-75-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1476A. | |
| Adrenomedullin (1-52), human | Adrenomedullin is an antimicrobial peptide produced by adrenal medulla, skin, Homo sapiens (Human). It has antibacterial activity against Gram-positive and Gram-negative bacteria. In addition to controlling fluid-electrolyte homeostasis, adrenomedullin is an effective vasodilatory peptide hormone and can inhibit ACTH secretion of pituitary gland. Synonyms: H-Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys(1)-Arg-Phe-Gly-Thr-Cys(1)-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2; L-tyrosyl-L-arginyl-L-glutaminyl-L-seryl-L-methionyl-L-asparagyl-L-asparagyl-L-phenylalanyl-L-glutaminyl-glycyl-L-leucyl-L-arginyl-L-seryl-L-phenylalanyl-glycyl-L-cysteinyl-L-arginyl-L-phenylalanyl-glycyl-L-threonyl-L-cysteinyl-L-threonyl-L-valyl-L-glutaminyl-L-lysyl-L-leucyl-L-alanyl-L-histidyl-L-glutaminyl-L-isoleucyl-L-tyrosyl-L-glutaminyl-L-phenylalanyl-L-threonyl-L-alpha-aspartyl-L-lysyl-L-alpha-aspartyl-L-lysyl-L-alpha-aspartyl-L-asparagyl-L-valyl-L-alanyl-L-prolyl-L-arginyl-L-seryl-L-lysyl-L-isoleucyl-L-seryl-L-prolyl-L-glutaminyl-glycyl-L-tyrosinamide (16->21)-disulfide; Human adrenomedullin; Adrenomedullin (human); Human adrenomedullin-(1-52)-NH2. Grades: >95%. CAS No. 148498-78-6. Molecular formula: C264H406N80O77S3. Mole weight: 6028.82. | |
| Alarelin acetate | Alarelin acetate is a synthetic Gonadotrophin-releasing hormone agonist. It is the acetate form of a hypothalamic peptide. It is a potent LH-RH agonist in rats and mice. It reversibly delays sexual maturation in rats, stimulates spawning activity in fish. It could inducte ovulation and is used to treat endmometriosis. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Uses: Alarelin acetate could inducte ovulation and is used to treat endmometriosis. it is responsible for the secretion of gonadotropins, luteinizing hormone (lh) and follicle-stimulating hormone (fsh), from the pituitary glands. Synonyms: LHRH-A; 6-D-Ala-10-D-gly-LHRH-ethylamide; Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt; 6-D-Ala-10-D-gly-LHRH-ethylamide; (S)-1-((3S,6S,9S,12S,15R,18S,21S)-3-((1H-imidazol-5-yl)methyl)-6-((1H-indol-3-yl)methyl)-21-(3-((diaminomethylene)amino)propyl)-12-(4-hydroxybenzyl)-9-(hydroxymethyl)-18-isobutyl-15-methyl-1,4,7,10,13,16,19-heptaoxo-1-((S)-5-oxopyrrolidin-2-yl)-2,5,8,11,14,17,20-heptaazadocosan-22-oyl)-N-ethylpyrrolidine-2-carboxamide diacetate. Grades: >98%. CAS No. 79561-22-1. Molecular formula: C60H86N16O16. Mole weight: 1287.42. | |
| Amezinium methylsulfate | Amezinium methylsulfate, a sympathomimetic drug used for the treatment of low blood pressure, increases the arterial blood pressure and heart rate of anaesthetized animals and of pithed rats by stimulating vascular alpha- and cardiac beta 1-adrenoceptors. Synonyms: Amezinium Metilsulfate; LU-1631; LU 1631; LU1631; Regulton; Risumic. 6-methoxy-1-phenylpyridazin-1-ium-4-amine methylsulfate;AMEZINIUM METHYL SULFATE;SUPRATONIN (GRUNENTHAL);RISUMIC (DAINIPPON);REGULTON (KNOLL);4-amino-6-methoxy-1-phenyl-pyridaziniumethylsulfate;4-amino-6-methoxy-1-phenylpyridazinium-methylsulfat;4-amino-. CAS No. 30578-37-1. Molecular formula: C11H12N3O.CH3O4S. Mole weight: 313.33. | |
| Anterior Lobe Pituitary Powder(Porcine) | Anterior Lobe Pituitary Powder(Porcine). Categories: betamethasone sodium phosphate; 151-73-5. |  CA, FL & NJ |
| Antiparallel Dimer-AVP | Antiparallel Dimer-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Anti-Parallel Dimer-Vasopressin; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2.H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6', Cys1'-Cys6); 2[L-cystyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparginyl-L-cystyl-L-prolyl-L-arginyl-glycinamide] (inter-disulfide bridges between 1,6' and 1',6 cysteines). Molecular formula: C92H130N30O24S4. Mole weight: 2168.48. | |
| (Arg8,des-Gly-NH29)-Vasopressin | (Arg8,des-Gly-NH29)-Vasopressin is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Des-Gly-OH-Vasopressin; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-OH (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginine (1->6)-disulfide; Des-Gly-OH-AVP; 9-Deglycinamide-argipressin; 9-des-GlyNH2-argipressin; 1-8-Vasopressin, 8-L-arginine-; 8-L-Arginine-1-8-vasopressin; Vasopressin, 8-L-arginine-9-deglycinamide-; 8-Arginine-9-deglycinamide-vasopressin; 8-Arginine-9-desglycinamide vasopressin; [Arg8,de-Gly9]-vasopressin; Org 5667; [Deglycinamide9,arginine8]-vasopressin; [Desglycinamide9-arginine8]-vasopressin; Arginine vasopressin-(1-8). Grades: ≥95% by HPLC. CAS No. 37552-33-3. Molecular formula: C44H61N13O12S2. Mole weight: 1028.17. | |
| (Arg8)-Vasopressin (free acid) | Gly-OH-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Gly 9-Vasopressin; Arg-Vasopressin-Acid; Gly-OH Vasopressin; L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycine (1->6)-disulfide; Gly-OH Argipressin; Vasopressin, 8-L-arginine-9-glycine-; 8-L-Arginine-9-glycinevasopressin; (Arg8)-Vasopressinoic acid; [Arg8,Gly-OH9]vasopressin; Vasopressinoic acid; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-OH (Disulfide bridge: Cys1-Cys6); Gly-OH-AVP. Grades: ≥95%. CAS No. 25255-33-8. Molecular formula: C46H64N14O13S2. Mole weight: 1085.23. | |
| Argipressin Acetate | Argipressin Acetate is an antidiuretic hormone secreted from the posterior pituitary. Argipressin acts via V1A receptors in blood vessels, causing vasoconstriction, and via V2 receptors in the renal tubules, causing anti-diuresis. Synonyms: Argipressin monoacetate; (Cys-Tyr-Phe-Gln-Asn-Cys)Cycl-Pro-Arg-Gly-NH2 acetate salt; Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 acetate salt; Antidiuretic hormone acetate salt; Arginine vasopressin acetate salt; [ARG8]-vasopressin acetate salt. Grades: 98%. CAS No. 129979-57-3. Molecular formula: C48H69N15O14S2. Mole weight: 1144.28. | |
| Asp(5)-AVP | Asp(5)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Asp5-AVP; Asp(5)-Arg-Vasopressin; Asp(5)-Vasopressin; Vasopressin, 5-L-aspartic acid-8-L-arginine-; H-Cys-Tyr-Phe-Gln-Asp-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 78031-79-5. Molecular formula: C46H64N14O13S2. Mole weight: 1085.22. | |
| β-Asp(5)-AVP | β-Asp(5)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: β-Asp(5)-Vasopressin; H-Cys-Tyr-Phe-Gln-β-Asp-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-β-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. Molecular formula: C46H64N14O13S2. Mole weight: 1085.22. | |
| β-Endorphin (1-26) (human) trifluoroacetate salt | β-endorphin (1-26) is a neuropeptide found in rat hippocampus, brain stem, and pituitary. It is an opioid receptor agonist that inhibits potassium-induced norepinephrine (NE) release in rat cortical slices (IC50 = 2.5 nM). Grades: ≥95%. Molecular formula: C130H208N32O38S·xCF3COOH. Mole weight: 2859.3. | |
| BF 2649 | Pitolisant hydrochloride is an antagonist of the histamine H3 receptor, which is used for the treatment of narcolepsy with or without cataplexy in adult patients. Uses: The treatment of narcolepsy with or without cataplexy. Synonyms: BF 2649; BF2649; BF-2649; pitolisant hydrochloride; Wakix; 1-[3-[3- (4-chlorophenyl) propoxy]propyl]piperidine hydrochloride. CAS No. 903576-44-3. Molecular formula: C17H27Cl2NO. Mole weight: 332.309. | |
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