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| Product | Description | |
|---|---|---|
| PIT 1 | PIT 1. Group: Biochemicals. Grades: Purified. CAS No. 53501-41-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| PIP3 Antagonist II, DM-PIT-1, N- ( (2-Hydroxy-5-nitrophenyl) carbamothioyl) -3, 5-dimethylbenzamide, N- ( ( (2-Hydroxy-5-nitrophenyl) amino) thioxomethyl) -3, 5-dimethyl-benzamide, Akt Inhibitor XXII, PDK1 Inhibitor VI) | A cell-permeable benzoylthiourea compound that is shown to compete against PIP3 for binding PH domains of Akt1 (IC50 >31uM), ARNO, GRP1, and P1. Effectively blocks PIP3-dependent cellular PI3K-PDK1-Akt signaling pathway activation in U87MG (25 to 100uM for 3d) and PDGF-induced Akt and GRP membrane translocation in serum-starved SUM159 cells (1h 100uM pretreatment), while being inactive against PDGF-induced Btk translocation or PMA-induced PLC-delta and TAPP1/2 translocations. Although DM-PIT-1 can be administered as a DMSO stock for effective culture treatments, incorporating DM-PIT-1 into PEG-PE mixed micelles enhances its solubility (up to 1mM) and i.v. dosing limit for more effective in vivo administrations (5% vs. 41% of control 4T1 tumor size in mice via 1mg/kg micelles-formulated or 0.4mg/kg free drug daily i.v., respectively). Group: Biochemicals. Grades: Highly Purified. CAS No. 701947-53-7. Pack Sizes: 25mg. Molecular Formula: C??H??N?O?S, Molecular Weight: 345.4. US Biological Life Sciences. | Worldwide |
| PIT-1 | PIT-1 is a selective PIP3 (phosphatidylinositol 3,4,5-trisphosphate) antagonist. PIT-1 inhibits cancer cell survival and induces apoptosis by inhibition of PIP3 dependent PI3K / Akt signaling. PIT-1 exhibits antitumor activity in vivo [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 53501-41-0. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103224. |  |
| Pitavastatin Impurity 10 | Pitavastatin Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-4-hydroxytetrahydro-2H-pyran-2-one. CAS No. 141750-63-2. Molecular formula: C25H22FNO3. Mole weight: 403.45. Catalog: APB141750632. |  |
| Rosuvastatin Impurity 61 (Pitavastatin Impurity 64) | Rosuvastatin Impurity 61 (Pitavastatin Impurity 64). Uses: For analytical and research use. Group: Impurity standards. CAS No. 124752-23-4. Molecular formula: C13H22O5. Mole weight: 258.31. Catalog: APB124752234. | |
| 2-Amino-2'-fluorobenzophenone | 2-Amino-2'-fluorobenzophenone is an intermediate in the preparation of the anticholesteremic Pitavastatin. Group: Biochemicals. Grades: Highly Purified. CAS No. 1581-13-1. Pack Sizes: 100mg, 1g. Molecular Formula: C13H10FNO, Molecular Weight: 215.22. US Biological Life Sciences. | Worldwide |
| 2-Amino-2'-fluorobenzophenone | An intermediate in the synthesis of Pitavastatin, a HMG-CoA reductase inhibitor that lowers LDL cholesterol and triglycerides and increase HDL cholesterol in your blood. Synonyms: 2-Amino-2'-fluoro-benzophenone; (2-Amino-phenyl)-(2-fluoro-phenyl)-methanone. Grade: ≥ 95%. CAS No. 1581-13-1. Molecular formula: C13H10FNO. Mole weight: 215.22. |  |
| 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinoline-d5 3-Aldehyde | Pitavastatin intermediate. Group: Biochemicals. Alternative Names: 4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-aldehyde-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol | Pitavastatin intermediate. Group: Biochemicals. Alternative Names: 2-Cyclopropyl-4-(4'-fluorophenyl) Quinolyl-3-methanol. Grades: Highly Purified. CAS No. 121660-11-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol-d5 | Pitavastatin intermediate. Group: Biochemicals. Alternative Names: 2-Cyclopropyl-4-(4'-fluorophenyl) Quinolyl-3-methanol-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| [ [2-Cyclopropyl-4- (4-fluorophenyl) -3-quinolinyl] methyl] triphenyl-phosphonium Bromide | [ [2-Cyclopropyl-4- (4-fluorophenyl) -3-quinolinyl] methyl] triphenyl-phosphonium Bromide is an impurity from the synthesis of HMG-CoA reductase inhibitor Pitavastatin [P531040, (Z)-Pitavastatin Calcium Salt]. Group: Biochemicals. Grades: Highly Purified. CAS No. 154057-58-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C37H30BrFNP. US Biological Life Sciences. | Worldwide |
| ((2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)methyl)triphenylphosphonium bromide | [[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]methyl]triphenyl-phosphonium Bromide is an impurity in the production of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: Pitavastatin Impurity 44 Bromide; Phosphonium, [[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]methyl]triphenyl-, bromide (1:1). Grade: ≥95%. CAS No. 154057-58-6. Molecular formula: C37H30BrFNP. Mole weight: 618.52. | |
| 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol | 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol is one of Pitavastatin intermediates. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Uses: Pitavastatin intermediate. Synonyms: 2-Cyclopropyl-4-(4'-fluorophenyl)Quinolyl-3-methanol; Pitavastatin Impurity 31. Grade: ≥95%. CAS No. 121660-11-5. Molecular formula: C19H16FNO. Mole weight: 293.33. | |
| 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester | 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester is an impurity of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 868536-53-2. Pack Sizes: 50mg, 500mg. Molecular Formula: C20H17NO2. US Biological Life Sciences. | Worldwide |
| (2-Cyclopropyl-4-phenylquinolin-3-yl)methanol | (2-Cyclopropyl-4-phenylquinolin-3-yl)methanol is an impurity of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 250mg. Molecular Formula: C19H17NO. US Biological Life Sciences. | Worldwide |
| 2-Cyclopropyl-4-phenylquinoline-3-carbaldehyde | 2-Cyclopropyl-4-phenylquinoline-3-carbaldehyde is an impurity of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C19H15NO. US Biological Life Sciences. | Worldwide |
| 3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline | 3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline is used to prepare artificial HMG-CoA reductase inhibitors. It is also used to synthesize pitavastatin calcium via stereoselective Wittig olefination reaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 154057-56-4. Pack Sizes: 100mg, 500mg. Molecular Formula: C19H15BrFN. US Biological Life Sciences. | Worldwide |
| 3-Cyclopropyl-3-oxopropanoic Acid Methyl Ester | A reagent used in the synthesis of Pitavastatin. Group: Biochemicals. Alternative Names: Methyl 3-Cyclopropyl-3-oxopropionate; Methyl 2- (Cyclopropylcarbonyl) acetate; β-Oxo-cyclopropanepropanoic Acid Methyl Ester. Grades: Highly Purified. CAS No. 32249-35-7. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| (3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt | (3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt. Group: Biochemicals. Alternative Names: Defluoro Pitavastatin. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C25H24NNaO4 , Molecular Weight: 425.45. US Biological Life Sciences. | Worldwide |
| (3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid tert-Butyl Ester | (3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid tert-Butyl Ester is an intermediate in the synthesis of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: (3R,5S,E)-Tert-butyl 7-(2-cyclopropyl-4-phenylquinolin-3-yl)-3,5-dihydroxyhept-6-enoate; Pitavastatin Impurity compound C; 2-Methyl-2-propanyl (3R,5S,6E)-7-(2-cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoate; 6-Heptenoic acid, 7-(2-cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-. Grade: 97%. Molecular formula: C29H33NO4. Mole weight: 459.58. | |
| (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt | (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Group: Biochemicals. Alternative Names: ent-NK-104; Pitavastatin 3S,5R-Isomer Calcium Salt. Grades: Highly Purified. CAS No. 254452-88-5. Pack Sizes: 2.5mg. Molecular Formula: C25H24FNO4 1/2Ca, Molecular Weight: 440.49. US Biological Life Sciences. | Worldwide |
| (3S,5R)-Pitavastatin Calcium | A metabolite of Pitavastatin which is a potent inhibitor of HMG-CoA reductase (Ki = 1.7 nM). Synonyms: ent-NK-104; Pitavastatin 3S,5R-Isomer Calcium Salt; (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Grade: > 95%. CAS No. 254452-88-5. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.86. | |
| (3S,5S)-Pitavastatin Calcium Salt | A metabolite of Pitavastatin which has a potent cholesterol-lowering action. Synonyms: 3-Epi-NK-104; Pitavastatin 3S,5S-Isomer Calcium Salt; (3S,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Grade: > 95%. CAS No. 254452-92-1. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.5. | |
| 4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic Acid Methyl Ester | 4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic Acid Methyl Ester is an intermediate of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylic Acid Methyl Ester; Methyl 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylate; Methyl 4-(4'-fluorophenyl)-2-(cyclopropyl)-3-quinolinecarboxylate; 3-Quinolinecarboxylic acid, 2-cyclopropyl-4-(4-fluorophenyl)-, methyl este; Pitavastatin Impurity 32. Grade: ≥95%. CAS No. 121659-86-7. Molecular formula: C20H16FNO2. Mole weight: 321.34. | |
| 4-(4-Fluorophenyl)-2-cyclopropylquinoline-3-carboxylic Acid Methyl Ester | Pitavastatin intermediate. Group: Biochemicals. Alternative Names: 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylic Acid Methyl Ester; Methyl 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylate. Grades: Highly Purified. CAS No. 121659-86-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 4-Dehydroxy-3-dehydro-pitavastatin-d5 Lactone | A labeled metabolite of Pitavastatin in humans and monkeys. Group: Biochemicals. Alternative Names: (6S) -6- [ (1E) -2- [2-Cyclopropyl-d5-4- (4-fluorophenyl) -3-quinolinyl] ethenyl] tetrahydro-2H-pyran-2-one. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 5,6-Epoxyeicosatrienoic acid | 5,6-Epoxyeicosatrienoic acid (5,6-EET; (±)5,6-EpETrE) is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5,6-Epoxyeicosatrienoic acid degrades into 5,6-DiHET and 5,6-δ-lactone, which can be converted to 5,6-DiHET and quantified by GC-MS. In neuroendocrine cells, such as the anterior pituitary and pancreatic islets, 5,6-Epoxyeicosatrienoic acid has been implicated in the mobilization of calcium and hormone secretion. 5,6-Epoxyeicosatrienoic acid is an inhibitor of T-type voltage-gated calcium channels (Cav3) that inhibits isoforms Cav3.1, Cav3.2 ( IC 50 =0.54 μM), and Cav3. and decreases nifedipine-resistant phenylephrine-induced vasoconstriction in isolated mouse mesenteric arteries via Cav3.2 blockade when used at a concentration of 3 μM. In addition, it is a substrate of COX-1 and COX-2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5,6-EET; (±)5,6-EpETrE. CAS No. 87173-80-6. Pack Sizes: 25 μg (312.04 μM * 250 μL in Ethanol); 50 μg (312.04 μM * 500 μL in Ethanol); 100 μg (312.04 μM * 1 mL in Ethanol). Product ID: HY-132184. | |
| 6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine | 6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine is one of Pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: 9-cyclopropyl-15-fluoro-8-azatetracyclo; Pitavastatin Impurity 3 (PP-3). Grade: 98%. CAS No. 1187966-94-4. Molecular formula: C20H16FN. Mole weight: 289.35. | |
| 6-Cyclopropyl-10-fluorobenzo[k]phenanthridine | 6-Cyclopropyl-10-fluorobenzo[k]phenanthridine is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin Impurity 4 (PP-4). Grade: 98%. CAS No. 1187966-95-5. Molecular formula: C20H14FN. Mole weight: 287.33. | |
| (6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-5,6-dihydro-2H-pyran-2-one | (6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-5,6-dihydro-2H-pyran-2-one is an impurity in the production of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: (S)-6-{(E)-2-[2-Cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-vinyl}-5,6-dihydro-pyran-2-one; Pitavastatin Impurity 29; (S,E)-6-(2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-5,6-dihydro-2H-pyran-2-one; 2H-Pyran-2-one, 6-((1E)-2-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl)ethenyl)-5,6-dihydro-, (6S)-; 2H-Pyran-2-one, 6-(2-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl)ethenyl)-5,6-dihydro-, (S-(E))-. Grade: ≥95%. CAS No. 148516-15-8. Molecular formula: C25H20FNO2. Mole weight: 385.43. | |
| 7-?[2-?cyclopropyl-?4-?(4-?fluorophenyl)?-?3-?quinolinyl]?-?3,?5-?dihydroxy-6-?Heptenoic acid | An isomer of Pitavastatin. Pitavastatin is a potent HMG-CoA reductase inhibitor. CAS No. 121659-03-8. Molecular formula: C25H24FNO4. Mole weight: 421.468. | |
| 8-L-Arginine-9a-glycine-vasopressin | An impurity of Vasopressin. Vasopressin is a nonapeptide hormone produced in the hypothalamus and released by the posterior pituitary gland. It is used clinically to manage central diabetes insipidus, treat hypotension in shock, and control gastrointestinal bleeding. Synonyms: Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-Gly-OH(Cys1&Cys6 bridge); CYFQNCPRGG-OH(Cys1&Cys6 bridge); L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycyl-glycine (1->6)-disulfide; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-Gly-OH (Disulfide bridge: Cys1-Cys6); Endo-Gly9a-Vasopressin. Grade: ≥95%. CAS No. 114665-05-3. Molecular formula: C48H67N15O14S2. Mole weight: 1142.27. | |
| Abarelix | Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Synonyms: Plenaxis, PPI-149; PPI 149; PPI149; R-3827; R 3827; R3827. Grade: 98%. CAS No. 183552-38-7. Molecular formula: C72H95ClN14O14. Mole weight: 1416.09. | |
| Ac-Asp(5)-AVP | Ac-Asp(5)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Ac-Asp(5)-Vasopressin; N-Ac-Asp(5)-AVP; [Cys(Ac)1-Asp(5)]-Argipressin; Ac-Cys-Tyr-Phe-Gln-Asp-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Acetyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 2594426-06-7. Molecular formula: C48H66N14O14S2. Mole weight: 1127.26. | |
| Ac-AVP | Ac-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Vasopressin, N-acetyl-8-L-arginine-; Vasopressin, 1-(N-acetyl-L-cysteine)-8-arginine; Vasopressin, 8-acetylarginine; 1-Acetylcysteine-8-arginine-vasopressin; N-Acetyl-Vasopressin; N-acetyl-L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide; Ac-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); Ac-Vasopressin; N-Acetyl-8-L-argininevasopressin. CAS No. 38106-69-3. Molecular formula: C48H67N15O13S2. Mole weight: 1126.28. | |
| Acetyl PACAP (1-38) (human, mouse, ovine, porcine, rat) trifluoroacetate salt | Acetyl pituitary adenylate cyclase-activating peptide (PACAP) (1-38) is an N-terminally acetylated form of PACAP (1-38). Synonyms: Acetyl pituitary adenylate cyclase-activating peptide (1-38). Grade: ≥95%. Molecular formula: C205H333N63O54S·xCF3COOH. Mole weight: 4576.29. | |
| ACTH (1-10), human | Adrenocorticotropic hormone (ACTH) (1-10) is an N-terminal peptide fragment of ACTH, a peptide hormone produced by the anterior pituitary gland that is involved in the biological stress response. Synonyms: H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-OH; L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycine; ACTH (1-10) (human, mouse, rat, porcine, bovine, ovine); Adrenocorticotropic Hormone (1-10); Corticotropin (1-10); Adrenocorticotropic Hormone (ACTH) (1-10), human. Grade: ≥97% by HPLC. CAS No. 2791-5-1. Molecular formula: C59H78N16O16S. Mole weight: 1299.41. | |
| ACTH 1-17 | ACTH (1-17) is a peptide fragment of ACTH, a tropic hormone produced by the anterior pituitary. Synonyms: Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg; Alpha1-17-ACTH; a1-17-Corticotropin; L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophyl-glycyl-L-lysyl-L-prolyl-L-valyl-glycyl-L-lysyl-L-lysyl-L-arginine; 1-Ala-17-Lys-ACTH 4-amino-n-butylamide; 1-beta-Alanine-17-(L-2,6-diamino-N-(4-aminobutyl)hexanamide)-alpha1-17-corticotrophin; alsactide; Synchrodyn; Adrenocorticotropic Hormone Fragment 1-17 human, rat. Grade: 98%. CAS No. 7266-47-9. Molecular formula: C95H145N29O23S. Mole weight: 2093.41. | |
| ACTH (1-17) TFA | ACTH (1-17) TFA is a peptide fragment of ACTH, a tropic hormone produced by the anterior pituitary. Synonyms: α1-17-ACTH (TFA); L-Seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginine.TFA; a1-17-Corticotropin.TFA; acth(1-17).TFA,human; Adrenocorticotropic Hormone Fragment 1-17.TFA human, rat; Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg.TFA. Grade: ≥98%. Molecular formula: C95H145N29O23S.C2HF3O2. Mole weight: 2207.43. | |
| ACTH (1-39) (Human) | Potent endogenous melanocortin receptor 2 (MC2) agonist (EC50 = 57 pM). Component of the hypothalamic-pituitary-adrenal (HPA) axis that stimulates glucocorticoid production and release from the adrenal cortex. Induces insulin resistance, promotes a proinflammatory profile and stimulates UCP-1 in adipocytes in vitro. Group: Biochemicals. Alternative Names: Adrenocorticotropic hormone (1-39); Adrenocorticotropin; Corticotropin. Grades: Highly Purified. CAS No. 12279-41-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| ACTH (1-39), Porcine | ACTH (1-39) is a potent agonist of melanocortin receptor 2 (MC2R) with an EC50 value of 57 pM in HeLa cells expressing the mouse receptor. Synonyms: Adrenocorticotropic Hormone from porcine pituitary; Adrenocorticotropic Hormone Fragment 1-39; Corticotropin A. Grade: 95%. CAS No. 9061-27-2. Molecular formula: C210H314N56O57S. Mole weight: 4567.15. | |
| ACTH (18-39) (human) | ACTH (18-39) (human) is a C-terminal peptide fragment of ACTH, a tropic hormone produced by the anterior pituitary. Synonyms: Adrenocorticotropic Hormone (ACTH) (18-39), human; H-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH; L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-prolyl-L-asparagyl-glycyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-prolyl-L-leucyl-L-alpha-glutamyl-L-phenylalanine; Adrenocorticotropic Hormone Fragment 18-39 human; CLIP. Grade: ≥95%. CAS No. 53917-42-3. Molecular formula: C112H165N27O36. Mole weight: 2465.67. | |
| ACTH (18-39), human TFA | ACTH (18-39) (human) is a C-terminal peptide fragment of ACTH, a tropic hormone produced by the anterior pituitary. Synonyms: Adrenocorticotropic Hormone (ACTH) (18-39), human TFA; CLIP (human) (TFA); Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe.TFA; L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-prolyl-L-asparagyl-glycyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-prolyl-L-leucyl-L-alpha-glutamyl-L-phenylalanine.TFA. Grade: >98%. CAS No. 73724-75-1. Molecular formula: C112H165N27O36.C2HF3O2. Mole weight: 2579.69. | |
| ACTH 22-39 | ACTH (22-39) is a peptide fragment of ACTH, a tropic hormone produced by the anterior pituitary. Synonyms: Adrenocorticoptropic Hormone Fragment 22-39; ACTH (22-39) (human); H-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH; L-valyl-L-tyrosyl-L-prolyl-L-asparagyl-glycyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartyl-L-alpha-glutamyl-L-seryl-L-alanyl-L-alpha-glutamyl-L-alanyl-L-phenylalanyl-L-prolyl-L-leucyl-L-alpha-glutamyl-L-phenylalanine; beta-Cell-Tropin. Grade: ≥95% by HPLC. CAS No. 37548-29-1. Molecular formula: C90H125N19O32. Mole weight: 1985.06. | |
| Adrenocorticotropic hormone | Adrenocorticotropic hormone (ACTH) is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone regulates cortisol and androgen production [1] [2]. Uses: Scientific research. Group: Peptides. Alternative Names: ACTH; Adrenocorticotrophic hormone. CAS No. 9002-60-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-106373. | |
| Adrenocorticotropic Hormone (ACTH) (18-39), human TFA | Adrenocorticotropic Hormone (ACTH) (18-39), human TFA is a corticotropinlike intermediate lobe peptide, which is is produced in the melanotrophs of the intermediate lobe of the pituitary [1]. Uses: Scientific research. Group: Peptides. Alternative Names: CLIP (human) TFA. CAS No. 73724-75-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1476A. | |
| Adrenomedullin (1-52), human | Adrenomedullin is an antimicrobial peptide produced by adrenal medulla, skin, Homo sapiens (Human). It has antibacterial activity against Gram-positive and Gram-negative bacteria. In addition to controlling fluid-electrolyte homeostasis, adrenomedullin is an effective vasodilatory peptide hormone and can inhibit ACTH secretion of pituitary gland. Synonyms: H-Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys(1)-Arg-Phe-Gly-Thr-Cys(1)-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2; L-tyrosyl-L-arginyl-L-glutaminyl-L-seryl-L-methionyl-L-asparagyl-L-asparagyl-L-phenylalanyl-L-glutaminyl-glycyl-L-leucyl-L-arginyl-L-seryl-L-phenylalanyl-glycyl-L-cysteinyl-L-arginyl-L-phenylalanyl-glycyl-L-threonyl-L-cysteinyl-L-threonyl-L-valyl-L-glutaminyl-L-lysyl-L-leucyl-L-alanyl-L-histidyl-L-glutaminyl-L-isoleucyl-L-tyrosyl-L-glutaminyl-L-phenylalanyl-L-threonyl-L-alpha-aspartyl-L-lysyl-L-alpha-aspartyl-L-lysyl-L-alpha-aspartyl-L-asparagyl-L-valyl-L-alanyl-L-prolyl-L-arginyl-L-seryl-L-lysyl-L-isoleucyl-L-seryl-L-prolyl-L-glutaminyl-glycyl-L-tyrosinamide (16->21)-disulfide; Human adrenomedullin; Adrenomedullin (human); Human adrenomedullin-(1-52)-NH2. Grade: >95%. CAS No. 148498-78-6. Molecular formula: C264H406N80O77S3. Mole weight: 6028.82. | |
| Alarelin | Alarelin is a synthetic analog of Gonadotropin-releasing hormone (GnRH) used primarily for its effects on the reproductive system. It acts as a GnRH agonist, initially stimulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland. Alarelin is used in the treatment of conditions such as endometriosis, uterine fibroids, and prostate cancer, as well as in assisted reproductive technologies. Synonyms: 1-9-Luteinizing hormone-releasing factor (swine), 6-D-alanine-9-(N-ethyl-L-prolinamide)-; Luteinizing hormone-releasing factor (pig), 6-D-alanine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-; AY 25205; Dalarelin; Dalareline; L 4513; LHRH-A2; LRH-A2; Luteinizing hormone-releasing hormone analog 2; Surfagon; TAP 127; Wy 18481; H-Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt; L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-proline ethylamide; (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH; Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt; LHRH-A; 6-D-Ala-10-D-gly-LHRH-ethylamide; L-Pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-proline ethylamide. Grade: 95%. CAS No. 52435-06-0. Molecular formula: C56H78N16O12. Mole weight: 1167.32. | |
| Alarelin diacetate | Alarelin acetate is a synthetic Gonadotrophin-releasing hormone agonist. It is the acetate form of a hypothalamic peptide. It is a potent LH-RH agonist in rats and mice. It reversibly delays sexual maturation in rats, stimulates spawning activity in fish. It could inducte ovulation and is used to treat endmometriosis. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Uses: Alarelin acetate could inducte ovulation and is used to treat endmometriosis. it is responsible for the secretion of gonadotropins, luteinizing hormone (lh) and follicle-stimulating hormone (fsh), from the pituitary glands. Synonyms: 1-9-Luteinizing hormone-releasing factor (swine), 6-D-alanine-9-(N-ethyl-L-prolinamide)-, acetate (1:2); 1-9-Luteinizing hormone-releasing factor (swine), 6-D-alanine-9-(N-ethyl-L-prolinamide)-, diacetate (salt); Luteinizing hormone-releasing factor (pig), 6-D-alanine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-, diacetate (salt); Alarelin acetate; H-Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt.2C2H4. Grade: >98%. CAS No. 79561-22-1. Molecular formula: C60H86N16O16. Mole weight: 1287.42. | |
| Amezinium methylsulfate | Amezinium methylsulfate, a sympathomimetic drug used for the treatment of low blood pressure, increases the arterial blood pressure and heart rate of anaesthetized animals and of pithed rats by stimulating vascular alpha- and cardiac beta 1-adrenoceptors. Synonyms: Amezinium Metilsulfate; LU-1631; LU 1631; LU1631; Regulton; Risumic. 6-methoxy-1-phenylpyridazin-1-ium-4-amine methylsulfate; AMEZINIUM METHYL SULFATE; SUPRATONIN (GRUNENTHAL); RISUMIC (DAINIPPON); REGULTON (KNOLL); 4-amino-6-methoxy-1-phenyl-pyridaziniumethylsulfate; 4-amino-6-methoxy-1-phenylpyridazinium-methylsulfat; 4-amino-. CAS No. 30578-37-1. Molecular formula: C11H12N3O.CH3O4S. Mole weight: 313.33. | |
| Anterior Lobe Pituitary Powder(Porcine) | Anterior Lobe Pituitary Powder(Porcine). Categories: betamethasone sodium phosphate; 151-73-5. |  CA, FL & NJ |
| Antiparallel Dimer-AVP | Antiparallel Dimer-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Anti-Parallel Dimer-Vasopressin; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2.H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6', Cys1'-Cys6); 2[L-cystyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparginyl-L-cystyl-L-prolyl-L-arginyl-glycinamide] (inter-disulfide bridges between 1,6' and 1',6 cysteines). Molecular formula: C92H130N30O24S4. Mole weight: 2168.48. | |
| (Arg8,des-Gly-NH29)-Vasopressin | (Arg8,des-Gly-NH29)-Vasopressin is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Des-Gly-OH-Vasopressin; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-OH (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginine (1->6)-disulfide; Des-Gly-OH-AVP; 9-Deglycinamide-argipressin; 9-des-GlyNH2-argipressin; 1-8-Vasopressin, 8-L-arginine-; 8-L-Arginine-1-8-vasopressin; Vasopressin, 8-L-arginine-9-deglycinamide-; 8-Arginine-9-deglycinamide-vasopressin; 8-Arginine-9-desglycinamide vasopressin; [Arg8,de-Gly9]-vasopressin; Org 5667; [Deglycinamide9,arginine8]-vasopressin; [Desglycinamide9-arginine8]-vasopressin; Arginine vasopressin-(1-8). Grade: ≥95% by HPLC. CAS No. 37552-33-3. Molecular formula: C44H61N13O12S2. Mole weight: 1028.17. | |
| (Arg8)-Vasopressin (free acid) | Gly-OH-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Gly 9-Vasopressin; Arg-Vasopressin-Acid; Gly-OH Vasopressin; L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-arginyl-glycine (1->6)-disulfide; Gly-OH Argipressin; Vasopressin, 8-L-arginine-9-glycine-; 8-L-Arginine-9-glycinevasopressin; (Arg8)-Vasopressinoic acid; [Arg8,Gly-OH9]vasopressin; Vasopressinoic acid; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-OH (Disulfide bridge: Cys1-Cys6); Gly-OH-AVP. Grade: ≥95%. CAS No. 25255-33-8. Molecular formula: C46H64N14O13S2. Mole weight: 1085.23. | |
| Argipressin Acetate | Argipressin Acetate is an antidiuretic hormone secreted from the posterior pituitary. Argipressin acts via V1A receptors in blood vessels, causing vasoconstriction, and via V2 receptors in the renal tubules, causing anti-diuresis. Synonyms: Argipressin monoacetate; (Cys-Tyr-Phe-Gln-Asn-Cys)Cycl-Pro-Arg-Gly-NH2 acetate salt; Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2 acetate salt; Antidiuretic hormone acetate salt; Arginine vasopressin acetate salt; [ARG8]-vasopressin acetate salt. Grade: 98%. CAS No. 129979-57-3. Molecular formula: C48H69N15O14S2. Mole weight: 1144.28. | |
| Asp(5)-AVP | Asp(5)-AVP is an impurity of Vasopressin, which is an antidiuretic hormone secreted from the posterior pituitary. Synonyms: Asp5-AVP; Asp(5)-Arg-Vasopressin; Asp(5)-Vasopressin; Vasopressin, 5-L-aspartic acid-8-L-arginine-; H-Cys-Tyr-Phe-Gln-Asp-Cys-Pro-Arg-Gly-NH2 (Disulfide bridge: Cys1-Cys6); L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-aspartyl-L-cysteinyl-L-prolyl-L-arginyl-glycinamide (1->6)-disulfide. CAS No. 78031-79-5. Molecular formula: C46H64N14O13S2. Mole weight: 1085.22. | |
| BF 2649 | Pitolisant hydrochloride is an antagonist of the histamine H3 receptor, which is used for the treatment of narcolepsy with or without cataplexy in adult patients. Uses: The treatment of narcolepsy with or without cataplexy. Synonyms: BF 2649; BF2649; BF-2649; pitolisant hydrochloride; Wakix; 1-[3-[3-(4-chlorophenyl)propoxy]propyl]piperidine hydrochloride. CAS No. 903576-44-3. Molecular formula: C17H27Cl2NO. Mole weight: 332.309. | |
| Bromocriptine | Bromocriptine, an ergoline derivative, is a dopamine agonist. It is used in the treatment of pituitary tumors, Parkinson's disease (PD), hyperprolactinaemia, neuroleptic malignant syndrome, and type 2 diabetes. Synonyms: (5'-a2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-alpha-(2-methylpropyl)ergotamin-3'; 2-bromo-alpha-ergocryptine; 2-bromo-alpha-ergokryptin; 2-bromo-alpha-ergokryptine; 2-bromoergocryptine; (5'a)-2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-ergotama. Grade: > 95%. CAS No. 25614-03-3. Molecular formula: C32H40BrN5O5. Mole weight: 654.61. | |
| BW A868C | Prostaglandin D2 (PGD2) has been widely distributed in rat brain, spinal cord and pituitary and may act as a neuromodulator in the central nervous system. BW A868C is a novel, selective and potent competitive antagonist of PGD2. BW A868C antagonizes the prostaglandin D2 and BW 245C-induced activation of human platelet adenylate cyclase. BW A868C antagonizes the accumulation of cAMP in rabbit non-pigmented ciliary epithelial cells. However, it has virtually no effect on human TP, IP, EP1, EP2, and FP receptors. Synonyms: BWA-868C; BWA868C. Grade: ≥98%. CAS No. 118675-50-6. Molecular formula: C25H37N3O5. Mole weight: 459.6. | |
| Cabergoline | Cabergoline is a lysergic acid amide derivative and a potent dopamine D2 receptor agonist. It has been used for monotherapy of Parkinson's disease in the early phase. It has a direct inhibitory effect on pituitary lactotroph (prolactin) cells. It acts on dopamine receptors in lactophilic hypothalamus cells to suppress prolactin production in the pituitary gland. It has been used as a first-line agent in the management of prolactinomas due to its higher affinity for D2 receptor sites, less severe side effects, and more convenient dosing schedule than the older bromocriptine. It is developed by Johnson & Johnson. It has been approved the listing. Uses: Cabergoline has been used for monotherapy of parkinson's disease in the early phase. it has been used as a first-line agent in the management of prolactinomas. Synonyms: CG-101; FCE-21336; CG 101; FCE 21336; CG101; FCE21336; Cabaser; Cabaseril; 6-Allyl-n-[3-(dimethylamino)propyl]-n-(ethylcarbamoyl)ergoline-8-carboxamide; (8-Beta)-(2-propenyl); n-(3-(dimethylamino)propyl)-n-((ethylamino)carbonyl)-6-ergoline-8-carboxamide; Cabergolinum; (8β)-N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propen-1-yl)-ergoline-8-carboxamide. Grade: >98%. CAS No. 81409-90-7. Molecular formula: C26H37N5O2. Mole weight: 451.60. | |
| Capromorelin tartrate | Capromorelin, also known as CP-424,391, is a growth hormone secretagogue and ghrelin mimetic ( hGHS-R1a K(I)=7 nM, rat pituicyte EC(50)=3 nM). Initial studies have shown the drug to directly raise insulin growth factor 1 (IGF-1) and growth hormone levels. Capromorelin showed enhanced intestinal absorption in rodent models and exhibited superior pharmacokinetic properties, including high bioavailabilities in two animal species [F(rat)=65%, F(dog)=44%]. This short-duration GHS was orally active in canine models and was selected as a development candidate for the treatment of musculoskeletal frailty in elderly adults. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CP-424,391; CP 424,391; CP424,391; CP-424391; CP 424391; CP424391; CP-424,391-18; Capromorelin tartrate. Product Category: Others. Appearance: Solid powder. CAS No. 193273-69-7. Molecular formula: C32H41N5O10. Mole weight: 655.71. Purity: >98%. IUPACName: 2-amino-N-((R)-1-((R)-3a-benzyl-2-methyl-3-oxo-2,3,3a,4,6,7-hexahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)-3-(benzyloxy)-1-oxopropan-2-yl)-2-methylpropanamide (2R,3R)-2,3-dihydroxysuccinate. Canonical SMILES: CC(C)(N)C(N[C@@H](C(N(C[C@]12CC3=CC=CC=C3)CCC1=NN(C)C2=O)=O)COCC4=CC=CC=C4)=O.O[C@H]([C@H](C(O)=O)O)C(O)=O. Product ID: ACM193273697. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Cathepsin L Inhibitor | Cathepsin L inhibitor is a potent inhibitor of cathepsin L with IC50 of 0.85 nM. It is trypanocidal with an ED50 value of 45 nM against T. brucei that is well below the ED50 value of 21,500 nM for human HL-60 cells. In vivo, cathepsin L inhibitor (2.5-10 mg/kg) inhibits bone loss in a mouse model of osteoporosis in a dose-dependent manner. Cathepsin L inhibitor can also completely suppress osteoclastic pit formation on femur slices isolated from bovine cortical bone. Synonyms: Z-FY-CHO; Z-Phe-Tyr-aldehyde; SB 412515; N-(benzyloxycarbonyl)-phenylalanyl-l-tyrosinal. Grade: ≥95%. CAS No. 167498-29-5. Molecular formula: C26H26N2O5. Mole weight: 446.49. | |
| Cepharanthine | Cepharanthine (CEP) is a biscoclaurine alkaloid isolated from Stephania cepharantha. It has anticancer, antiinflammatory, antiallergic, immunomo- dulatory, and many other interesting biological activities. Cepharanthine has been widely used in Japan for more than 40 years to treat a wide variety of acute and chronic diseases. CEP inhibits tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppresses cytokine production. It has also been shown to scavenge free radicals and to have a protective effect against some of the responses mediated by pro-inflammatory cytokines such as TNF-α, interleukin (IL)-1β and IL6. CEP has successfully been used to treat a diverse range of medical conditions, including radiation-induced leukopenia, idiopathic thrombocytopenic purpura, alopecia areata, alopecia pityrodes, venomous snakebites, xerostomia, sarcoidosis, refractory anemia and various cancer-related conditions. No safety issues have been observed with CEP, and side effects are very rarely reported. Uses: Anti-tumor/anti-inflammatory. Synonyms: Cepharanthin; NSC-623442; 6',12'-Dimethoxy-2,2'-dimethyl-6,7-(methylenebis(oxy))oxyacanthan; (+)-Cepharanthine; O-Methylcepharanoline; Cepharantin; [14aS-(14aR*,26aS*)]-2,3,13,14,14a,15,26,26a-Octahydro-22,30-dimethoxy-1,14-dimethyl-1H-4,6:16,19-dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2',3': | |
| Cetrorelix Acetate | Cetrorelix Acetate is the acetate salt of cetrorelix, which is a potent and synthetic peptide antagonist of gonadotropin-releasing hormone (GnRH) receptor antagonist with IC50 value of 1.21 nM. It binds to radioligand murine LTK- cells with Kd value of 0.2 nM. It inhibits the activation of hGnRHR and a downstream luciferase reporter gene in murine LTK- cells by the GnRHR agonist [D-Trp6]GnRH. It suppresses production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary gland. It prevents ovulation during in vitro fertilization. It causes prepubertal reduction in bone density, bone strength and bone modeling. It was used as a therapeutic agent for the treatment of blood cancers such as multiple myeloma (MM). It is also used to treat hormone-sensitive cancers of the breast and prostate. It also has antidepressant and anxiolytic activity in vivo. Uses: Fertility agents, female. Synonyms: D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, acetate (1:x); D-Alaninamide, N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N5-(aminocarbonyl)-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-, acetate (salt); Cetrotid; C. Grade: >98%. CAS No. 145672-81-7. Molecular formula: C70H92ClN17O14.xC2H4O2. Mole weight: 1431.06 (free base) | |
| Chorionic gonadotrophin | Chorionic gonadotrophin (hCG) is a gonadotropin that can be isolated from the anterior pituitary gland. Chorionic gonadotrophin has potential applications in ovarian and follicular development [1]. Uses: Scientific research. Group: Natural products. Alternative Names: hCG; Chorionic gonadotropic hormone. CAS No. 9002-61-3. Pack Sizes: 5000 U. Product ID: HY-107953. | |
| Ciclopirox EP Impurity C | An impurity of Ciclopirox. Ciclopirox is an antifungal medication used to treat various fungal skin infections, including athlete's foot (tinea pedis), jock itch (tinea cruris), ringworm (tinea corporis), and pityriasis versicolor (tinea versicolor). It works by inhibiting fungal growth and disrupting the integrity of fungal cell membranes. Synonyms: 6-Cyclohexyl-4-methylpyridin-2(1H)-one; N-Deshydroxy Ciclopirox; Ciclopirox olamine EP Impurity C; Ciclopirox Impurity C; 6-Cyclohexyl-4-methyl-2(1H)-pyridinone; Ciclopirox olamine impurity C [EP]. Grade: 95%. CAS No. 67587-24-0. Molecular formula: C12H17NO. Mole weight: 191.27. | |
| CJC1295 With DAC | CJC1295 is a synthetic analogue of growth hormone-releasing hormone. Uses: Cjc1295 with dac, also known as dac:grf (1-29), is a synthetic modification of the growth hormone releasing hormone (ghrh) peptide. this peptide is designed to stimulate the pituitary gland to produce and release growth hormone (gh) in a more sustained manner than natural ghrh. it contains a series of amino acids designed to mimic the effects of natural ghrh in the body. the addition of dac (drug. Grade: 98%. CAS No. 446262-90-4. Molecular formula: C165H269N47O46. Mole weight: 3647.19. | |
| CK-666 | CK-666 is a cell-permeable actin-related protein Arp2/3 complex inhibitor (IC50=12 ?M). CK-666 binds to Arp2/3 complex, stabilizes the inactive state of the complex, blocking movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 442633-00-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-16926. | |
| CL 82198 hydrochloride | The hydrochloride salt form of CL 82198, an inhibitor of MMP-13, has been found to restrain in vitro invasion by the human pituitary adenoma cell line HP75. Synonyms: CL 82198 hydrochloride; CL82198 hydrochloride; CL-82198 hydrochloride; N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide hydrochloride. Grade: ≥98% by HPLC. CAS No. 1188890-36-9. Molecular formula: C17H23N2O3.HCl. Mole weight: 338.83. | |
| Climbazole | Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff and eczema. Climbazole has shown a high in vitro and in vivo efficacy against Pityrosporum ovale that appears to play an important role in the pathogenesis of dandruff. Its chemical structure and properties are similar to other fungicides such as ketoconazole and miconazole. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Crinipan AD;1-(4-chlorophenoxy)-3,3-dimethyl-1-(imidazol-1-yl)-butan-2-one;CLIMBAZOL;1-(4-chloro-phenoxy)-1-imidazol-1-yl-3,3-dimethyl-butan-2-one;1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethyl-2-butanone. Appearance: Off-white to pale yellow crystalline powder. CAS No. 38083-17-9. Molecular formula: C15H17ClN2O2. Mole weight: 292.76. Purity: 98%+. Density: 1.17 g/cmH3. Product ID: ACM38083179. Alfa Chemistry ISO 9001:2015 Certified. | |
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