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An acetyl-L-arginine analog of TAME that serves as a negative control. TAME is an ubiquitin ligase inhibitor that specifically blocks Anaphase-Promoting Complex (APC) activation. Group: Biochemicals. Grades: Highly Purified. CAS No. 1784-05-0. Pack Sizes: 50mg. Molecular Formula: C?H??N?O? · HCl, Molecular Weight: 266.7. US Biological Life Sciences.
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Anaphase-Promoting Complex Inhibitor, TAME (TAME Hydrochloride)
TAME is a potent ubiquitin ligase inhibitor that specifically blocks Anaphase-Promoting Complex (APC) activation by directly binding to APC and disrupts the IR-tail-dependent interactions between APC and its activator proteins Cdc20 or Cdh1. It stabilizes APC substrates and is shown to inhibit cyclin proteolysis in mitotic Xenopus egg extract with an IC50=12uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 1784-03-8. Pack Sizes: 50mg. Molecular Formula: C??H??N?O?S · HCl, Molecular Weight: 378.87. US Biological Life Sciences.
It is a heparin-binding amino acid sequence found in the heparin-binding domain at the carboxy-terminal of fibronectin. Synonyms: Heparin Binding Peptide; H-Trp-Gln-Pro-Pro-Arg-Ala-Arg-Ile-OH; L-tryptophyl-L-glutaminyl-L-prolyl-L-prolyl-L-arginyl-L-alanyl-L-arginyl-L-isoleucine. Grades: ≥97% by HPLC. CAS No. 125720-21-0. Molecular formula: C47H74N16O10. Mole weight: 1023.19.
Fibronectin Adhesion-promoting Peptide acetate
It is a heparin-binding amino acid sequence found in the heparin-binding domain at the carboxy-terminal of fibronectin. Synonyms: Heparin Binding Peptide acetate. Molecular formula: C49H78N16O12. Mole weight: 1083.25.
A cell-permeable 2,6-diaminopyridine compound that directly binds HSF1 and reversibly inhibits its transcriptional activity (IC50=1.2uM in heat shocked p[HSE]4-Ta-Luc transfected HCT-116 cells), and suppresses both the transcription and expression of hsp70, hsp47 and hsp27. Shown to block heat shock-induced p-TEFb (positive transcription elongation factor b) recruitment to the hsp70 promoter and inhibit the phosphorylation of RNA Pol II CTD-Ser2 with no effect on TNF-a-stimulated NF-kB activity in HeLa cells. Induces G2/M growth arrest and apoptosis (IC50 ~5uM in HCT-116 cells), and further decreases tumor growth in mouse xenograft regression model (50mg/kg, i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
A cell-permeable phenylhydrazone that restores mitochondrial tubular network formation in MEF lacking either of the two outer mitochondrial membrane (OMM) mitofusins (EC50=5.3 and 4.42 mM, respectively, in Mfn1 or Mfn2 knockout MEF cells) or in MPP+-treated SH-SY5Y cells (5uM 24h), but not in MEF lacking both Mfn1/2 or the inner mitochondrial membrane (IMM) fusion mediator Opa1 (optic atrophy1). M1 (5uM 24h) is reported to boost the downregulated ATP5A & ATP5B protein level in Mfn1 or Mfn2 knockout MEF to the wild-type MEF level and ATPase inhibitor oligomycin at 5uM is shown to completely offset the mitochondrial fusion effect by 5uM M1 in Mfn1 knockout MEF. Comparing to mdivi-1, M1 exerts its effect via promoting fusion rather than inhibiting fission or division. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
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10-Nitrooleate
Nitrated unsaturated fatty acids, such as 10- and 12-nitrolinoleate, cholesteryl nitrolinoleate, and nitrohydroxylinoleate, represent a new class of endogenous lipid-derived signalling molecules. OA-NO2 activates PPARγ approximately 7-fold at a concentration of 1 μM and effectively promotes differentiation 3T3-L1 preadipocytes to adipocytes at 3 μM. Uses: Anti-inflammatory agents. Synonyms: 9-Octadecenoic acid, 10-nitro-, (9E)-; (9E)-10-Nitro-9-octadecenoic acid; (E)-10-Nitro-octadec-9-enoic acid; CXA 10; IMR 261; 10-Nitro Oleic Acid; (9E)-10-nitrooctadecenoic acid; 10-nitro-9E-octadecenoic acid. Grades: ≥98%. CAS No. 875685-46-4. Molecular formula: C18H33NO4. Mole weight: 327.46.
10- (O-2, 2-Dichloroethoxycarbonyl ) 13-(3-O-TES) 7-Epi Docetaxel is an impurity of Docetaxel Hydrate (D494420), a semisynthetic derivative of Paclitaxel(P132500), which is an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antine oplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C52H69Cl2NO16Si, Molecular Weight: 1063.08999999999. US Biological Life Sciences.
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10-O-2,2-Dichloroethoxycarbonyl Docetaxel
10-O-2,2-Dichloroethoxycarbonyl Docetaxel is an impurity of Docetaxel (D494420); an antineoplastic and antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. Group: Biochemicals. Grades: Highly Purified. CAS No. 158810-73-2. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C46H55Cl2NO16. US Biological Life Sciences.
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1,1,1-Trichloro-Trifluoroethane
1,1,1-Trichlorotrifluoroethane is used in the synthesis of isosteres showing potential to be β-turn promoters. Also used in the synthesis of fluoro-containing alkenes. Synonyms: 1,1,1-Trifluoro-2,2,2-trichloroethane; 1,1,1-Trifluorotrichloroethane. Grades: > 95%. CAS No. 354-58-5. Molecular formula: C2Cl3F3. Mole weight: 187.38.
1,1'-Bis(dimethylsilyl)ferrocene
Catalytic co-initiator in free radical photopolymerization and free radical promoted cationic polymerization reactions Reactant for: Hydrosilylataion and hydroboration reactions Platinum/nickel catalyzed selective hydrosilylation of alkynes and alkenes Iron-catalyzed dehydrogenative coupling reactions Hydrosilylation and double silylation of carbonyl compounds. Group: Polymer/macromolecule. Alternative Names: 1,1-BIS(DIMETHYLSILYL)FERROCENE;1,1-Bis(dimethylsilyl)ferrocene 97%;Ferrocene,1,1-bis(dimethylsilyl)-. CAS No. 1295-15-4. Molecular formula: C14H22FeSi2 10*. Mole weight: 302.34. Catalog: ACM1295154.
1,1-Diethoxy-2-methyl-2-propanol
1,1-Diethoxy-2-methyl-2-propanol is an intermediate in the synthesis of metabolites of docetaxel (D494420), an antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. Group: Biochemicals. Grades: Highly Purified. CAS No. 108994-55-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H18O3. US Biological Life Sciences.
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1,2-Bis(Triethoxysilyl)Ethane
It is Colorless transparent liquid. Uses: It can be used as adhesion promoter.used as additive to silane coupling agent formulations and enhance hydrolytic stability. used in corrosion resistant coating/primers for steel & aluminum. Group: Saltself-assembly materials self assembly and lithographyposs nanohybrid materials self assembly and contact printing materials. Alternative Names: Ethylenebis(triethoxysilane); triethoxy(2-triethoxysilylethyl)silane; 4,4,7,7-Tetraethoxy-3,8-dioxa-4,7-disiladecane. CAS No. 16068-37-4. Pack Sizes: 10 g; 100 g. Product ID: triethoxy(2-triethoxysilylethyl)silane. Molecular formula: 354.59. Mole weight: C14H34O6Si2. CCO[Si](CC[Si](OCC)(OCC)OCC)(OCC)OCC. InChI=1S/C14H34O6Si2/c1-7-15-21 (16-8-2, 17-9-3)13-14-22 (18-10-4, 19-11-5)20-12-6/h7-14H2, 1-6H3. IZRJPHXTEXTLHY-UHFFFAOYSA-N. 95%.
1,2-Bis(Triethoxysilyl)Ethane
It is Colorless transparent liquid. Uses: It can be used as adhesion promoter.used as additive to silane coupling agent formulations and enhance hydrolytic stability. used in corrosion resistant coating/primers for steel & aluminum. Alternative Names: Ethylenebis(triethoxysilane); triethoxy(2-triethoxysilylethyl)silane; 4, 4, 7, 7-Tetraethoxy-3, 8-dioxa-4, 7-disiladecane. CAS No. 16068-37-4. Molecular formula: C14H34O6Si2. Mole weight: 354.59. Appearance: Clolorless liquid. Purity: 0.95. IUPACName: triethoxy(2-triethoxysilylethyl)silane. Canonical SMILES: CCO[Si](CC[Si](OCC)(OCC)OCC)(OCC)OCC. Density: 0.958 g/mL. ECNumber: 2402122. Catalog: ACM16068374.
1,2-Didecanoyl-sn-glycerol
1,2-Didecanoyl-sn-glycerol increases ornithine decarboxylase activity associated with tumor promotion in mouse skin. It can also function as a bioregulator of protein kinase C in human platelets. Group: Biochemicals. Grades: Highly Purified. CAS No. 60514-49-0. Pack Sizes: 10mg, 25mg. Molecular Formula: C23H44O5, Molecular Weight: 400.59. US Biological Life Sciences.
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1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine
1,2-Dilauroyl-sn-glycero-3-phosphoethanolamine is a phosphatidylethanolamine with lauric acid. Phosphatidylethanolamine is a phospholipid found in all living organisms, particularly in nervous tissue. It serves as a precursor of phosphatidylcholine, and promotes membrane fusion, oxidative phosphorylation, mitochondrial biogenesis, and autophagy. Synonyms: DLEA; DLPE; Dilauroyl phosphatidylethanolamine; PE(12:0/12:0); 1,2-didodecanoyl-sn-glycero-3-phosphoethanolamine. Grades: ≥98%. CAS No. 42436-56-6. Molecular formula: C29H58NO8P. Mole weight: 579.76.
1,2-Dioctanoyl-sn-glycerol 3-Phosphate Sodium Salt
1,2-Dioctanoyl-sn-glycerol 3-Phosphate is a derivative of sn-1,2-Dioctanoylglycerol (D481000) which is a cell permeable lipid shown to mimic the effect of tumor-promoting phorbol diesters on mitogenesis and EGF binding and action in intact cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 178603-80-0. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C19H37O8P xNa, Molecular Weight: US Biological Life Sciences.
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1-(2-Furyl)ethanol
1-(2-Furyl)ethanol is an intermediate in the synthesis of 2H-Furo[2,3-c]pyran-2-one derivatives of their germination-promoting activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 4208-64-4. Pack Sizes: 500mg, 1g. Molecular Formula: C6H8O2, Molecular Weight: 112.13. US Biological Life Sciences.
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1-(2-Furyl)ethanol-d3
1-(2-Furyl)ethanol-d3 is the isotope labelled analog of 1-(2-Furyl)ethanol (F865260), which is an intermediate in the synthesis of 2H-Furo[2,3-c]pyran-2-one derivatives of their germination-promoting activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 132331-94-3. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C6H5D3O2. US Biological Life Sciences.
1-(2-O-Acetyl-5-O-(p-toluoyl)-3-deoxy-3-fluoro-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is an intricate chemical complex, specifically beneficial in anti-viral pharmaceutical research. It is commonly used to promote studies on treatment modalities for diseases such as HIV. Grades: ≥95%. CAS No. 2072145-80-1. Molecular formula: C20H19FN2O8. Mole weight: 434.37.
1-((2R,6S)-6-(Hydroxymethyl)morpholin-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, a small molecule inhibitor, possesses remarkable potency against various cancer types. Its mechanism of action involves targeting proteins essential for cancer cell growth and replication, promoting tumor shrinkage and cell death. As demonstrated in lung, breast, colon, and ovarian cancer, it exhibits impressive antitumor activity, embodying a promising candidate for cancer therapy. Synonyms: Morpholino thymidine; 1-((2R,6S)-6-(hydroxymethyl)morpholin-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-[(2R,6S)-6-(Hydroxymethyl)-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; YML1Y6H5HD; 1-[(2R,6S)-6-(hydroxymethyl)morpholin-2-yl]-5-methylpyrimidine-2,4-dione; 1-((2R,6S)-6-(Hydroxymethyl)-2-morpholinyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-(6-Hydroxymethyl-morpholin-2-yl)-5-methyl-1H-pyrimidine-2,4-dione; 2,4(1H,3H)-Pyrimidinedione, 1-((2R,6S)-6-(hydroxymethyl)-2-morpholinyl)-5-methyl-; UNII-YML1Y6H5HD; SCHEMBL24420143; CS-0100784; A897935. CAS No. 179073-10-0. Molecular formula: C10H15N3O4. Mole weight: 241.24.
1,3:1,4-b-Glucotetraose (A)
1,3:1,4-b-Glucotetraose (A) is a carbohydrate compound with potential functionality in promoting the proliferation of beneficial gut microbiota. Synonyms: Glc1-3-Glc1-4-Glc1-4-Glc. CAS No. 58484-04-1. Molecular formula: C24H42O21. Mole weight: 666.58.
1, 3-Bis (methoxymethoxy) -5-[ (1E) -2-[4- (methoxymethoxy) phenyl]ethenyl]-benzene is a useful synthetic intermediate in the synthesis of Resveratrol Impurity B (H950990); an impurity of Resveratrol (R150000) which is a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet aggregation. Resveratrol is a specific inhibitor of COX-1 and also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion and progression. Group: Biochemicals. Grades: Highly Purified. CAS No. 1414361-09-3. Pack Sizes: 1g, 10g. Molecular Formula: C20H24O6, Molecular Weight: 360.4. US Biological Life Sciences.
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1-[3-(Trimethoxysilyl)Propyl]Urea
It is an essential silane coupling agent in the below industry: It is a diamine functional silane that find use as a coupling agent providing superior elongation, flexibility and spreading at the interface of polymers. It is used to promote adhesion between resins that react with amino groups and the surfaces of glass, mineral, metal, etc. Its reduced alkoxy functionality is also useful in waterborne systems by providing lower reactivity and therefore higher stability in the aqueous environment. Group: Biomaterials. Alternative Names: Gamma.-Ureidopropyltrimethoxysilane. CAS No. 23843-64-3. Molecular formula: C7H18N2O4Si. Mole weight: 222.32. Appearance: Amber transparent liquid. Purity: >94%. IUPACName: 3-trimethoxysilylpropylurea. Canonical SMILES: CO[Si](CCCNC(=O)N)(OC)OC. Density: 1.066 g/mL. ECNumber: 2459048. Catalog: ACM23843643.
1-[3-(Trimethoxysilyl)Propyl]Urea
1-[3-(Trimethoxysilyl)Propyl]Urea. Uses: It is an essential silane coupling agent in the below industry: it is a diamine functional silane that find use as a coupling agent providing superior elongation, flexibility and spreading at the interface of polymers. it is used to promote adhesion between resins that react with amino groups and the surfaces of glass, mineral, metal, etc. its reduced alkoxy functionality is also useful in waterborne systems by providing lower reactivity and therefore higher stability in the aqueous environment. Group: Saltself-assembly materials silane coupling agentsself assembly and contact printing materials. Alternative Names: Gamma.-Ureidopropyltrimethoxysilane. CAS No. 23843-64-3. Pack Sizes: In 25 L pail, 200 L drum and 1000 L IBC. Product ID: 3-trimethoxysilylpropylurea. Molecular formula: 222.32. Mole weight: C7H18N2O4Si. CO[Si](CCCNC(=O)N)(OC)OC. LVACOMKKELLCHJ-UHFFFAOYSA-N. >94%.
1,4:3,6-Dianhydrogalactitol
2-Hydroxymethylene-4,6-anhydro-galactopyranose, or 1,4:3,6-Dianhydrogalactitol, is a promising antineoplastic molecule with demonstrated efficacy against diverse cancers, such as those afflicting the brain, prostate, and breast tissue. Its chemo-preventive, cytotoxic, and apoptotic functions render it a potent impetus in caspase-3 pathways, effectively preventing malignant cells from proliferating and promoting their programmed death. The multifaceted potential of 1,4:3,6-Dianhydrogalactitol presents a compelling vehicle for cancer treatment that warrants continued exploration. CAS No. 915288-38-9.
1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea is an impurity of Sorafenib (S676850), a kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1129683-83-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C14H10ClF3N2O2, Molecular Weight: 330.69. US Biological Life Sciences.
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1- (4-Chloro-3- (trifluoromethyl) phenyl) urea
1- (4-Chloro-3- (trifluoromethyl) phenyl) urea is an impurity of Sorafenib (S676850); a multiple kinase inhibitor targeting both RAF and receptor tyrosine kinases that promote angiogenesis. Also antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C8H6ClF3N2O, Molecular Weight: 238.59. US Biological Life Sciences.
1-[4-(Dimethylamino)phenyl]-3-(2-hydroxy-3,4-dimethoxyphenyl)-1,3-propanedione is a reactant used in the preparation of 7,8-Dihydroxyflavone (D452830) derivatives which promote neurogenesis and exhibits potent antidepressant effect. Group: Biochemicals. Grades: Highly Purified. CAS No. 1205548-02-2. Pack Sizes: 50mg. US Biological Life Sciences.
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1,4-DPCA
1,4-DPCA nis a potent competitive inhibitor of avian prolyl 4-hydroxylase in embryonic chick tendon cells and human foreskin fibroblasts in vitro. It is a promotor of wound healing and tissue regeneration in mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 331830-20-7. Pack Sizes: 25mg, 50mg. Molecular Formula: C13H8N2O3, Molecular Weight: 240.21. US Biological Life Sciences.
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1,4-DPCA
The pro-angiogenic factor HIF-1α is targeted for destruction in non-hypoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-α prolyl hydroxylase (HIF-PH). It is a promotor of wound healing and tissue regeneration in mice. Synonyms: 1,4-dihydrophenonthrolin-4-one-3-carboxylic acid. Grades: ≥98%. CAS No. 331830-20-7. Molecular formula: C13H8N2O3. Mole weight: 240.2.
1,4-D-Xylobiose
1,4-D-Xylobiose is a vital substance used in the biomedical industry. It exhibits potential applications as a dietary supplement due to its prebiotic properties. It can serve as a nutrition source for beneficial gut bacteria, promoting a healthy intestinal environment. Synonyms: β1,4-D-Xylobiose; 4-O-(b-D-Xylopyranosyl)-D-xylopyranose; 1,4-β-Xylobiose; 4-O-β-D-Xylopyranosyl-D-xylose; Xylobiose. Grades: ≥98%. CAS No. 6860-47-5. Molecular formula: C10H18O9. Mole weight: 282.25.
Intermediate in the production of Rho kinase inhibitors and neurite outgrowth promoters. Group: Biochemicals. Alternative Names: N- [ [4- [ [ [ (1, 1-Dimethylethyl) dimethylsilyl] oxy] methyl] cyclohexyl] methylene] -α -methyl-benzenemethanamine. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
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1,5-anhydro-2,3,4,6-tetra-O-acetyl-D-glucitol
1,5-Anhydro-2,3,4,6-tetra-O-acetyl-D-glucitol, a synthetic compound with vast potential as both a diagnostic and therapeutic tool in the biomedical industry, boasts selective binding properties to glucose transporters on the surface of cancer cells for superior targeting. Moreover, this compound is poised as a treatment option for diabetes and other metabolic disorders as it promotes insulin sensitivity through glucose mimicry. Synonyms: 1,5-Anhydro-D-glucitol 2,3,4,6-Tetraacetate; 2,6-Anhydro-L-gulitol Peracetate; Polygalitol Tetraacetate; 1,5-Anhydroglucitol D-Tetraacetate. Grades: 98%. CAS No. 13137-69-4. Molecular formula: C14H20O9. Mole weight: 332.3.
15 β-OH Gibberellin A3 Methyl Ester
15 β-OH Gibberellin A3 Methyl Ester is an intermediate in synthesizing 15 β-OH Gibberellin A3 (G377485), which is a hormone that is found in plants which promotes the growth and elongation of cells. Gibberellic Acid acts as a plant growth regulator on account of its physiological and morphological effects in extremely low concentrations. Group: Biochemicals. Grades: Highly Purified. CAS No. 105593-24-6. Pack Sizes: 500ug, 1mg. Molecular Formula: C20H24O7. US Biological Life Sciences.
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(17 β)?-Estr-?4-?en-?17-?ol
(17 β)?-Estr-?4-?en-?17-?ol is an intermediate in synthesizing Ethylestrenol-d5 (E917832), an isotope labelled Ethylestrenol (E917830) is an anabolic steroid. Ethylestrenol is an illegal growth promoter used in livestock and are often tested for as part of a routine screening program for forbidden growth promoters. Group: Biochemicals. Grades: Highly Purified. CAS No. 3646-30-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C18H28O. US Biological Life Sciences.
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17 β-Hydroxy-17-methyl-4-oxa-5α-androstan-3-one
17 β-Hydroxy-17-methyl-4-oxa-5α-androstan-3-one is an impurity in the synthesis of Oxandrolone (O845050), A synthetic, anabolic steroid. Used to promote muscle growth and combat involuntary weight loss. It has also been used to treat cases of osteoporosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 4424-45-7. Pack Sizes: 10mg, 100mg. Molecular Formula: C19H30O3, Molecular Weight: 306.22. US Biological Life Sciences.
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1,8-Diazabicyclo[5.4.0]undec-7-ene
1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) can promote the methylation reaction of phenols, indoles and benzimidazoles with dimethyl carbonate under mild conditions. Synonyms: DBU; 1,8-Diazabicyclo[5.4.0]undecene-7; Alcanpoudre DBU 70-3KG; Amicure DBUE; Dabco DBU; Lupragen N 700; NSC 111184; NSC 230466; PC CAT DBU; Polycat DBU; U-CAT SA 851. Grades: ≥ 98%. CAS No. 6674-22-2. Molecular formula: C9H16N2. Mole weight: 152.24.
19-Norepiandrosterone
19-Norepiandrosterone is an metabolite of Nandrolone (N315000), an androgenic anabolic steroid illegally used as a growth-promoting agent in animal breeding and as a performance enhancer in athletics. Group: Biochemicals. Grades: Highly Purified. CAS No. 10002-93-4. Pack Sizes: 25mg, 250mg. Molecular Formula: C18H28O2, Molecular Weight: 276.41. US Biological Life Sciences.
Worldwide
1-EBIO
Activator of epithelial KCa channels, stimulates a large and sustained trans-epithelial Cl- secretory response across T84 monolayers. Induces hyperpolarization to the same magnitude as ACh in aortic value endothelial cells. Promotes embryonic stem cell (ESC) differentiation into cardiomyocytes. Group: Biochemicals. Grades: Highly Purified. CAS No. 10045-45-1. Pack Sizes: 10mg, 50mg. Molecular Formula: C9H10N2O. US Biological Life Sciences.
Worldwide
1-Methylhistamine
1-Methylhistamine (CAS# 501-75-7) is used in high fiber diets, promoting gluconeogenesis and inhibit glycolysis in muscle. Uses: Enzyme inhibitors. Synonyms: 2-(1-methyl-4-imidazolyl)ethanamine; 2-(1-methylimidazol-4-yl)ethanamine. Grades: > 95 %. CAS No. 501-75-7. Molecular formula: C6H11N3. Mole weight: 125.17.
1-Octyl Acetate
1-Octyl Acetate is a component in essential oil extracts from Arnebia linearifolia which has been seen to promote antioxidant and antimicrobial activity. It is also a flavour ester contributing to products and foods requiring a fruity characteristic. Group: Biochemicals. Grades: Highly Purified. CAS No. 112-14-1. Pack Sizes: 1g, 10g. Molecular Formula: C10H20O2, Molecular Weight: 172.26. US Biological Life Sciences.
Intermediate in the production of Rho kinase inhibitors and neurite outgrowth promoters. Group: Biochemicals. Alternative Names: trans-4- [ (1R) -1- [ [ (1, 1-Dimethylethoxy) carbonyl] amino] ethyl] cyclohexanecarboxylic Acid; trans-4- [ (R) -1- [ (tert-Butyloxycarbonyl) amino] ethyl] cyclohexanecarboxylic Acid. Grades: Highly Purified. CAS No. 671815-99-9. Pack Sizes: 10mg. US Biological Life Sciences.
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(1S, 2S) -2- (Dimethylamino) cyclohexan-1-ol
(1S, 2S) -2- (Dimethylamino) cyclohexan-1-ol is an organocatalysts that promotes highly enantioselective desymmetrizations of cyclic meso-anhydrides applying alcohol and benzyl mercaptan as nucleophiles. Group: Biochemicals. Grades: Highly Purified. CAS No. 29783-01-5. Pack Sizes: 1g, 2.5g. Molecular Formula: C8H17NO, Molecular Weight: 143.229999999999. US Biological Life Sciences.
(1S, 2S, 3S, 4S, 5R) -2, 3, 4-Tris (benzyloxy) -5- ( (benzyloxy) methyl) cyclohexyl 2,2,2-Trichloroacetimidate is an intermediate in the synthesis of KRN7000 (K660000), an important roles in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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1-Triacontanol
1-Triacontanol has been shown to increase plant growth through axilliary shoot proliferation. Uses: Triacontanol (tria) is a naturally occurring plant growth promotor that can be found in the epicuticular waxes of many types of plants. tria has been reported to increase the growth, yield and photosynthesis of plants. Group: Biobased pharmaceutical chemicals. Alternative Names: 1-Hydroxytriacontane; Melissyl Alcohol, TRIA. CAS No. 593-50-0. Molecular formula: C30H62O. Mole weight: 438.82 g/mol. Appearance: Off-white to Beige. Purity: 0.98. IUPACName: Triacontan-1-ol. Canonical SMILES: CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCO. Density: 0.87 g/ml. Catalog: BBC593500.
20-Deoxynarasin
20-Deoxynarasin is produced by the strain of Streptomyces aureofaciens NRRL 11181. It has anti-gram-positive bacteria, mycoplasma, coccidia and virus activity, and has effect on growth promotion. Synonyms: Deoxy-epi-narasin; 20-Deoxy-epi-17-narasin. Molecular formula: C43H72O10. Mole weight: 749.02.
20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid
20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid is a potent vasoconstrictor produced in vascular smooth muscle cells. Its EC50 value is < 10 nM. It is a cytochrome P450 metabolite. It induces diuresis by inhibiting Na+-K+-ATPase in proximal tubules and Na+/K+/Cl+ cotransporter in the thick ascending limb of Henle's loop in kidney. It is involved in the regulation of sodium, potassium, and chloride transport in the renal tubules. It is a vasoconstrictor that mediates pressure-induced autoregulatory vasoconstriction in rat cerebral microvessels. It is excreted mainly as the glucuronide conjugate. It can be further metabolized by cyclooxygenase to 20-hydroxy PGG2 and 20-hydroxy PGH2. It regulates blood pressure in a complex way. It sensitizes smooth muscle cells to the constrictor stimuli and promotes the proliferation of endothelial cells. It has the ability to induce proinflammatory changes. It blocked the 70 pS K+ channel localized in the apical membrane in TALH cells. It was found to be a potent vasoconstrictor through activating the kinase pathways that contribute to the vascular tone regulation including MAPK, PKC, rho kinase and src-type tyrosine kinase. It may similarly regulate blood pressure and contribute to the development of stroke and heart attacks. Synonyms: 20-Hydroxyeicosatetraeonic acid; 20 Hydroxyeicosatetraeonic acid; 20Hydroxyeicosatetraeonic acid; 20HETE; 20 HETE; 20-HETE;(5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid;20-Hydroxyeicosatetraenoic acid;20-hydroxy-5,8,11,14-eicosatetraenoic acid. Grades:>98%. CAS No. 79551-86-3. Molecular formula: C20H32O3. Mole weight: 320.47.
(20R)-Ginsenoside Rg3
Ginsenoside Rg3 is extracted from the roots of Panax ginseng C. A. Mey. It could enhance immunity and the ability of antivirus and infection. It also could protect hematopoietic function of marrow, improve the ability of hepatic detoxifcatio and promote restoration of hepatic tissue. It prevents and treats coronary heart disease, climacteric syndrome, diabetes, anemia. Synonyms: beta-D-Glucopyranoside,(3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl; 20(R)-Propanaxadiol; (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-2-[[(10R,12S,13R,14R,17S)-12-hydroxy-17-[(1R)-1-hydroxy-1,5-dimethyl-hex-4-enyl]-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-methylol-tetrahydropyran-3-yl]oxy-6-methylol-tetrahydropyran-3,4,5-triol. Grades: >98%. CAS No. 38243-03-7. Molecular formula: C42H72O13. Mole weight: 785.01.
2-(1a-methyl-6-oxo-3-phenoxy-1,1a,6,6a-tetrahydroindeno[1,2-b]azirine-6a-carboxamido)acetic acid is an impurity of Roxadustat. Roxadustat is a hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI). It promotes coordinated erythropoiesis through increasing endogenous erythropoietin, improving iron availability, and reducing hepcidin. Synonyms: (1a-methyl-6-oxo-3-phenoxy-1,1a,6,6a-tetrahydroindeno[1,2-b]azirine-6a-carbonyl)glycine; Rosastat impurity 02. CAS No. 2301113-15-3. Molecular formula: C19H16N2O5. Mole weight: 352.35.
2,2',3,5',6-Pentachlorobiphenyl
2,2',3,5',6-Pentachlorobiphenyl is an environmental neurotoxicant that promotes synaptogenesis through ryanodine receptor-dependent miR132 upregulation. Group: Biochemicals. Grades: Highly Purified. CAS No. 38379-99-6. Pack Sizes: 10mg, 100mg. Molecular Formula: C12H5Cl5, Molecular Weight: 326.43. US Biological Life Sciences.
2,2-Dichloroethanol + 2,2-Dichloroethyl (Trichloromethyl) Carbonate + 2,2-Dichloroethyl Carbonochloridate (Mixture) is an intermediate in the synthesis of 10-O-2,2-Dichloroethoxycarbonyl Docetaxel (D434415). 10-O-2,2-Dichloroethoxycarbonyl Docetaxel is an impurity of Docetaxel (D494420); an anti-neoplastic and anti-mitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg, 1g. Molecular Formula: C2H4Cl2O + C4H3Cl5O3 + C3H3Cl3O2, Molecular Weight: 114.96276331774. US Biological Life Sciences.
Worldwide
22-Hydroxycholest-4-en-3-one
22-Hydroxycholest-4-en-3-one was found in brain of Cyp46a1-/- mouse, indicating that this oxysterol promoted dopaminergic neurogenesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 60881-76-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C27H44O2, Molecular Weight: 400.64. US Biological Life Sciences.
Worldwide
(22R,23R)-28-Homo Brassinolide
(22R,23R)-28-Homo Brassinolideis a derivative of Brassinolide (B677050), a plant hormone; natural steroid containing a seven-membered B-ring lactone, that promotes both cell elongation and cell division. Group: Biochemicals. Grades: Highly Purified. CAS No. 82373-95-3. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C29H50O6, Molecular Weight: 494.7. US Biological Life Sciences.
Worldwide
(22RS,23RS)-28-Homo Brassinolide
(22RS,23RS)-28-Homo Brassinolide is a derivative of Brassinolide (B677050), a plant hormone; natural steroid containing a seven-membered B-ring lactone, that promotes both cell elongation and cell devision. Group: Biochemicals. Grades: Highly Purified. CAS No. 74174-44-0. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C29H50O6, Molecular Weight: 494.7. US Biological Life Sciences.
Worldwide
(22S,23S,24S)-24-Ethylbrassinone
(22S,23S,24S)-24-Ethylbrassinone is a derivative of Brassinolide (B677050), a plant hormone; natural steroid containing a seven-membered B-ring lactone, that promotes both cell elongation and cell devision. Group: Biochemicals. Grades: Highly Purified. CAS No. 83510-06-9. Pack Sizes: 10mg, 100mg. Molecular Formula: C29H50O5, Molecular Weight: 478.7. US Biological Life Sciences.
Worldwide
(22S,23S)-28-Homobrassinolide
A new class of steroidal phytohormones with high growth-promoting and antistress activity. Group: Biochemicals. Alternative Names: (1R, 3aS, 3bS, 6aS, 8S, 9R, 10aR, 10bS, 12aS) -1- [ (1S, 2S, 3S, 4S) -4-Ethyl-2, 3-dihydroxy-1, 5-dimethylhexyl] hexadecahydro-8, 9-dihydroxy-10a, 12a-dimethyl-6H-benz [c] indeno [5, 4-e] oxepin-6-one; Isohomobrassinolide; BR 120. Grades: Highly Purified. CAS No. 80483-89-2. Pack Sizes: 2mg, 5mg. US Biological Life Sciences.
Worldwide
(22S,23S)-28-Homo Brassinolide
A new class of steroidal phytohormones with high growth-promoting and antistress activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 80483-89-2. Pack Sizes: 1mg. Molecular Formula: C29H50O6. US Biological Life Sciences.
Worldwide
2-[3, 4-Epoxycyclohexyl) ethyl]trimethoxysilane
It is suitable for as polysulfide, polyurethane, epoxy, acrylic sealant and adhesive of the adhesion promoter, can significantly improve the sealants and adhesives for inorganic materials, such as glass, metal, concrete adhesion and water resistance. Group: Methoxysilane. Alternative Names: Trimethoxy[2-(7-oxabicyclo[4.1.0]hept-3-yl)ethyl]silane. CAS No. 2019-3-6. Molecular formula: C11H22O4Si. Mole weight: 246.38. Density: 1.065 g/mL at 25 °C(lit.). Catalog: ACM20190306.
2',3',5'-Tri-O-benzoyl-5-hydroxymethyluridine
2',3',5'-Tri-O-benzoyl-5-hydroxymethyluridine, a nucleoside analog exhibiting a remarkable therapeutic potential against various malignancies including lung and breast cancer, has enticed the attention of scientists and drug developers alike. Among several mechanisms, this compound is known to obstruct the biosynthesis of nucleotide and promote apoptosis. With its frequent employment in preclinical studies, 2',3',5'-Tri-O-benzoyl-5-hydroxymethyluridine represents a compelling candidate for the development of novel anticancer agents. Synonyms: (2R,3R,4R,5R)-2-((Benzoyloxy)methyl)-5-(5-(hydroxymethyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3,4-diyl dibenzoate; 5-hydroxymethyl-1-(tri-O-benzoyl-β-D-xylofuranosyl)-1H-pyrimidine-2,4-dione; 1-(2',3',5'-Tri-O-benzoyl-β-D-xylofuranosyl)-5-hydroxymethyl-uracil. Grades: ≥95%. CAS No. 53910-92-2. Molecular formula: C31H26N2O10. Mole weight: 586.55.
2,3,5-Tri-O-benzyl-D-arabinofuranosyl chloride
2,3,5-Tri-O-benzyl-D-arabinofuranosyl chloride, a chemical compound and starting material for antiviral and antitumor drugs, boasts noteworthy therapeutic effects against cancers like leukemia and lymphoma. Its DNA synthesis inhibition property, coupled with its role in apoptosis promotion, make it a promising candidate in combating cancer. CAS No. 52554-29-7. Molecular formula: C26H27ClO4. Mole weight: 438.94.
2,3-O-Isopropylidene-b-D-ribofuranosylamine p-toluenesulphonate salt
2,3-O-Isopropylidene-b-D-ribofuranosylamine p-toluenesulphonate salt is a specialized reagent commonly used in the synthesis of nucleoside analogs, which are integral to a variety of antiviral and anticancer drugs. It promotes efficient bond formation between complex molecules. Synonyms: 2,3-O-Isopropylidene-beta-D-ribofuranosylamine p-toluenesulfonate salt; 2,3-O-Isopropylidene-ss-D-ribofuranosylamine, p-Toluenesulfonate Salt;2,3-O-Isopropylidene-b-D-ribofuranosylamine p-toluenesulphonate salt; ((3AR,4R,6R,6aR)-6-amino-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol 4-methylbenzenesulfonate; [(3aR,4R,6R,6aR)-4-amino-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methanol; 4-methylbenzenesulfonic acid; 4-methylbenzene-1-sulfonic acid; [(3aR,4R,6R,6aR)-6-amino-2,2-dimethyl-tetrahydro-2H-furo[3,4-d][1,3]dioxol-4-yl]methanol;((3AR,4R,6R,6aR)-6-amino-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol4-methylbenzenesulfonate. CAS No. 29836-10-0. Molecular formula: C8H15NO4.C7H8O3S. Mole weight: 361.41.
2,4,5-Trichlorophenoxyacetic acid
2,4,5-Trichlorophenoxyacetic acid (2,4,5-T) is a synthetic plant hormone (auxin) that promotes processes such as somatic embryogenesis and selective gene transcription. It is also a herbicide that defoliates broad-leafed plants. 2,4,5-T together with 2,4-D comprises the defoliant Agent Orange. Group: Biochemicals. Alternative Names: 2,4,5-Trichlorophenoxyacetic Acid; 2- (2, 4, 5-Trichlorophenoxy) acetic Acid; (2, 4, 5-Trichlorophenoxy) acetic Acid; 2,4,5-T; Arbokan; BCF-Bushkiller; Forst U 46; Fortex; NSC 430; Trichlorophenoxyacetic acid; Trioxon; Verton 2T. Grades: Highly Purified. CAS No. 93-76-5. Pack Sizes: 25g. US Biological Life Sciences.
Intermediate in the production of cell death regulators and apoptosis promoters. Group: Biochemicals. Grades: Highly Purified. CAS No. 1027345-21-6. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
2-(4-Cyanobenzyl)thioadenosine
2-(4-Cyanobenzyl)thioadenosine, a biochemical compound, has garnered interest as a possible therapeutic remedy for a variety of ailments, including cancer and inflammatory disorders, due to its potential for retarding cellular growth and promoting cellular death in tumorous cells while concurrently working to mitigate inflammation in specific diseases. These biochemical effects arise through signaling pathways modulation, which in turn stimulate cell survival and proliferation. Grades: ≥95%. CAS No. 2095417-56-2. Molecular formula: C18H18N6O4S. Mole weight: 414.44.
2,4-Dinitrobenzenesulfenyl Chloride
2,4-Dinitrobenzenesulfenyl Chloride is used in the modification of chlorea toxins and its promoters. Group: Biochemicals. Grades: Highly Purified. CAS No. 528-76-7. Pack Sizes: 100mg, 500mg. Molecular Formula: C6H3ClN2O4S, Molecular Weight: 234.62. US Biological Life Sciences.