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An intermediate for the synthesis of Alpidem. Group: Biochemicals. Alternative Names: 6-Chloro-2- (4-chlorophenyl) -3- (N, N-di methyl amino methyl ene) imidazo [1, 2-a] pyridine. Grades: Highly Purified. CAS No. 365213-33-8. Pack Sizes: 25mg. US Biological Life Sciences.
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6-Methyl-2-pyridinemethanamine
6-Methyl-2-pyridinemethanamine. Group: Biochemicals. Alternative Names: 1-(6-Methyl-2-pyridinyl)methanamine; (6-Methylpyridin-2-yl)methylamine. Grades: Highly Purified. CAS No. 6627-60-7. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
(2-?Methyl-?1,?3-?thiazol-?5-?yl)?methanamine Hydrochloride can be used as reactant/reagent in preparation of sulfonamido methyl pyridinecaboxamide derivs. and analogs for use as negative modulators of NR2A. Group: Biochemicals. Grades: Highly Purified. CAS No. 1072806-59-7. Pack Sizes: 25mg, 50mg. Molecular Formula: C5H8N2S HCl, Molecular Weight: 128.203645999999. US Biological Life Sciences.
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3-(Aminomethyl)pyridine
3-(Aminomethyl)pyridine. Group: Biochemicals. Alternative Names: 3-Pyridinylmethyl)amine; 1-(Pyridin-3-yl)methanamine; 3-(Aminomethyl)pyridine; 3-Picolylamine; NSC 59706; Picolamine. Grades: Highly Purified. CAS No. 3731-52-0. Pack Sizes: 1g. US Biological Life Sciences.
3- (Dimethylaminomethyl) -6-methyl-2- (4-methylphenyl) imidazo[1, 2-a]pyridine-d6. Group: Biochemicals. Alternative Names: N, N, 6-Trimethyl-2- (4-methylphenyl) imidazo[1, 2-a]pyridine-3-methanamine-d6. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C18H15D6N3, Molecular Weight: 285.42. US Biological Life Sciences.
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4-(Aminomethyl)-3-fluoropyridine dihydrochloride
Pyridines. Alternative Names: (3-Fluoropyridin-4-yl)methanamine dihydrochloride. CAS No. 1257535-26-4. Molecular formula: C6H9Cl2FN2. Mole weight: 199.06. Catalog: ACM1257535264.
4-(Aminomethyl)pyridine
4-(Aminomethyl)pyridine is a compound that has derivatives that act as reversible inhibitors of various copper amine oxidases (CAOs). Group: Biochemicals. Alternative Names: 4-Pyridinemethanamine; 1-(Pyridin-4-yl)methanamine; 4-Picolinamine; 4-Picolinylamine; 4-Picolylamine; 4-Pyridinemethylamine; 4-Pyridinylmethanamine; 4-Pyridylmethylamine; C-(Pyridin-4-yl)methylamine; N-[ (4-Pyridinyl) methyl]amine; NSC 59707; Pyridin-4-ylmethylamine; γ-(Aminomethyl)pyridine; γ-Picolylamine; γ-Pyridylmethylamine. Grades: Highly Purified. CAS No. 3731-53-1. Pack Sizes: 5g. US Biological Life Sciences.
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(4-Chloropyridin-2-yl)methanamine dihydrochloride
Heterocyclic Organic Compound. Alternative Names: (4-CHLOROPYRIDIN-2-YL)METHANAMINE DIHYDROCHLORIDE;4-CHLORO-2-PYRIDINEMETHANAMINE DIHYDROCHLORIDE. CAS No. 114780-09-5. Molecular formula: C6H9Cl3N2. Mole weight: 215.50806. Catalog: ACM114780095.
SB 747651A dihydrochloride is a potent, ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor (IC50 = 11 nM in an in vitro kinase assay). SB 747651A has been shown to inhibit MSK1, MSK2, PKA, PKB, RSK and p70S6K activity in cells, and suppress IL-10 production in macrophages. Synonyms: SB747651A dihydrochloride; SB 747651A dihydrochloride; SB-747651A dihydrochloride; 2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-4-piperidinyl-1H-imidazo[4,5-c]pyridine-7-methanamine dihydrochloride. Grades: ≥98% by HPLC. CAS No. 1781882-72-1. Molecular formula: C16H22N8O.2HCl. Mole weight: 415.32.
[2-?(Oxan-?4-?yloxy)?pyridin-?3-?yl]?methanamine is an organic building block. Group: Biochemicals. Grades: Highly Purified. CAS No. 1250850-49-7. Pack Sizes: 100mg, 500mg. Molecular Formula: C11H16N2O2, Molecular Weight: 208.26. US Biological Life Sciences.
AMD 3465,a N-pyridinylmethylene monocyclam, is a selective antagonist of CXCL12/CXCR4-mediated interactions including ligand binding and receptor activation. With its enhanced potency against the CXCR4 receptor compared with plerixafor, AMD 3465 has been. Synonyms: N-(pyridin-2-ylmethyl)-1-[4-(1, 4, 8, 11-tetrazacyclotetradec-1-ylmethyl)phenyl]methanamine; hexahydrobromideAMD 3465 hexahydrobromide185991-07-5185991-24-6AMD3465 6 HBrC24H38N6.6BrHAMD3465; AMD 3465; AMD-3465GENZ-644494 N-(1,4,8,11- tetraazacyclotetradecanyl-1,4-phenylen. Grades: ≥98%. CAS No. 185991-24-6. Molecular formula: C24H38N6. Mole weight: 410.60.
Benzyl-(6-methyl-pyridin-2-ylmethyl)-amine
Heterocyclic Organic Compound. Alternative Names: CHEMBRDG-BB 4010340;BENZYL-(6-METHYL-PYRIDIN-2-YLMETHYL)-AMINE;ASINEX-REAG BAS 10149684;N-BENZYL-1-(6-METHYLPYRIDIN-2-YL)METHANAMINE. CAS No. 101938-10-7. Molecular formula: C14H16N2. Mole weight: 212.29. Catalog: ACM101938107.
CCT036477 is an inhibitor of Wnt signaling. Studies show that CCT036477 does not alter β-catenin levels but blocks transcription at the β-catenin level. CCT036477 inhibited growth in several cancer cell lines and showed clear activity in vivo, blocking development of Zebrafish and Xenopus embryos and expression of Wnt target genes. Group: Biochemicals. Alternative Names: α-(4-Chlorophenyl)-2-methyl-N-2-pyridinyl-1H-indole-3-methanamine. Grades: Highly Purified. CAS No. 305372-78-5. Pack Sizes: 25mg. US Biological Life Sciences.
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CMP5
CMP5 is a potent and selective PRMT5 inhibitor suppressing EBV-driven B-lymphocyte transformation while leaving normal B cells unaffected. Inhibition of PRMT5 effetively blocked recall T cell responses, reduced inflammation in delayed-type hypersensitivity and clinical disease in experimental autoimmune encephalomyelitis mouse models. Synonyms: CMP5; CMP 5; CMP-5; 1-(9-ethylcarbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine Hydrochloride; AKOS032401780. Grades: 99%. CAS No. 1030021-40-9. Molecular formula: C20H22N3.HCl. Mole weight: 351.87.
EW-7197 is a potent and selective ALK5 inhibitor, displaying antimetastatic and anticancer effects. It inhibits TGF-β/Smad signaling, and abrogates TGF-β1-induced tumor cell migration and invasion. EW-7197 inhibits breast cancer metastasis to the lung. EW-7197 prolongs the life span of BALB/c 4T1 mice via inhibition of EMT. EW-7197 inhibits metastasis and enhances the activity of cytotoxic T lymphocytes (CTLs) in 4T1 orthotopic grafted mice. Synonyms: Vactosertib; N-(2-fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-1H-imidazole-2-methanamine. Grades: >98%. CAS No. 1352608-82-2. Molecular formula: C22H18FN7. Mole weight: 399.433.
Netupitant Impurity 2
An impurity of Netupitant, which is a selective neurokinin 1 receptor antagonist with potential antiemetic activity. Synonyms: (6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)methanamine. Grades: > 95%. Molecular formula: C18H24N4. Mole weight: 296.42.
Netupitant Impurity 5
An impurity of Netupitant, which is a selective neurokinin 1 receptor antagonist with potential antiemetic activity. Synonyms: (6-(piperazin-1-yl)-4-(o-tolyl)pyridin-3-yl)methanamine. Grades: > 95%. Molecular formula: C17H22N4. Mole weight: 282.39.
N-Methyl(3-(pyridin-4-yl)phenyl)methanamine
N-Methyl(3-(pyridin-4-yl)phenyl)methanamine. Group: Biochemicals. Grades: Highly Purified. CAS No. 852180-67-7. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences.
It is a coupling agent for peptide synthesis and is particularly suitable for fragment condensation without racemization. Synonyms: TPTU; 2-(2-Pyridon-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate; O-(2-Oxo-1(2H)pyridyl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; o-(1,2-dihydro-2-oxo-1-pyridyl)-n,n,n',n'-tetramethyluronium tetrafluoroborate; MFCD00075475; AK170016; Methanaminium, N-[(dimethylamino)[(2-oxo-1(2H)-pyridinyl)oxy]methylene]-N-methyl-, tetrafluoroborate(1-) (1:1). Grades: 99 % (HPLC). CAS No. 125700-71-2. Molecular formula: C10H16N3O2.BF4. Mole weight: 297.06.
Sarizotan, also known as EMD-128130, is a full 5-HT1a agonist and a dopamine D2-like agonist/partial agonist used in clinical trials for the treatment of l-dopa-induced dyskinesia. Synonyms: 1-[(2R)-3,4-dihydro-2H-chromen-2-yl]-N-[[5-(4-fluorophenyl)pyridin-3-yl]methyl]methanamine;hydrochloride; EMD128130; sarizotan; 177976-12-4 (Sarizotan 2 HCl salt); 351862-32-3 (Sarizotan free base); sarizotan hydrochloride. Grades: >98%. CAS No. 195068-07-6. Molecular formula: C22H22ClFN2O. Mole weight: 384.88.
(-)-trans 3'-Aminomethyl Nicotine
(-)-trans 3'-Aminomethyl Nicotine is one of Nicotine derivatives, which is a potent parasympathomimetic stimulant. Synonyms: 3-Pyrrolidinemethanamine, 1-methyl-2-(3-pyridinyl)-, (2S,3R)-; (2S,3R)-1-Methyl-2-(3-pyridinyl)-3-pyrrolidinemethanamine; (2S,3R)-1-Methyl-2-(3-pyridyl)pyrrolidine-3-methanamine; 1-[(2S,3R)-1-Methyl-2-(3-pyridinyl)-3-pyrrolidinyl]methanamine. CAS No. 272124-60-4. Molecular formula: C11H17N3. Mole weight: 191.27.
Tris(2-pyridylmethyl)amine
ATRP for Everyone: Ligands and Initiators for the Clean Synthesis of Functional Polymers Atom Transfer Radical Polymerization (ATRP) ligand for the creation of telechelic polymers. Group: Amines. Alternative Names: ris(pyridin-2-ylmethyl)amine. CAS No. 16858-01-8. Molecular formula: C18H18N4. Mole weight: 290.36. Appearance: Solid. Purity: 0.97. IUPACName: 1-pyridin-2-yl-N,N-bis(pyridin-2-ylmethyl)methanamine. Canonical SMILES: C1=CC=NC (=C1)CN (CC2=CC=CC=N2)CC3=CC=CC=N3. Catalog: ACM16858018-2.
Tris(2-pyridylmethyl)amine
Tris(2-pyridylmethyl)amine. Uses: Atrp for everyone: ligands and initiators for the clean synthesis of functional polymers atom transfer radical polymerization (atrp) ligand for the creation of telechelic polymers. Group: Polymerization reagents. Alternative Names: ris(pyridin-2-ylmethyl)amine. CAS No. 16858-01-8. Pack Sizes: Packaging 250 mg in glass insert 1 g in glass bottle. Product ID: 1-pyridin-2-yl-N,N-bis(pyridin-2-ylmethyl)methanamine. Molecular formula: 290.36. Mole weight: C18H18N4. C1=CC=NC (=C1)CN (CC2=CC=CC=N2)CC3=CC=CC=N3. VGUWFGWZSVLROP-UHFFFAOYSA-N. InChI=1S/C18H18N4/c1-4-10-19-16 (7-1) 13-22 (14-17-8-2-5-11-20-17) 15-18-9-3-6-12-21-18/h1-12H, 13-15H2. 97%.
Vonoprazan
Vonoprazan is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+ ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. It is used to treat acid-related diseases. It can be used for the treatment of gastroduodenal ulcer (including some drug-induced peptic ulcers) and reflux esophagitis, and can be combined with antibiotics for the eradication of Helicobacter pylori. It is a pyrrole derivative with a chemical structure that is completely different from the P-CABs developed to date in vitro. It inhibits basal gastric acid secretion in a dose-dependent manner, and the ID50 value is 1.26 mg/kg in vivo. It shows a potent and longer-lasting inhibitory effect on the histamine-stimulated gastric acid secretion in rats and dogs. It shows significant antisecretory activity through high accumulation and slow clearance from the gastric tissue. It is unaffected by the gastric secretory state. It was developed by Takeda and Otsuda together. It has been listed. Uses: Vonoprazan is used to treat acid-related diseases. it can be used for the treatment of gastroduodenal ulcer (including some drug-induced peptic ulcers) and reflux esophagitis, and can be combined with antibiotics for the eradication of helicobacter pylori. Synonyms: TAK-438 free base;TAK438 free base; TAK 438 free base; Takecab;1-[5-(2-Fluorophenyl)-1-[(pyridin-3-yl)sulfonyl]-1H-pyrrol-3-yl]-N-methylmethanamine;1H-Pyrrole-3-methanamine,5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl). Grades: >98 %. CAS No. 881681-00-1. Molecular formula: C17H16FN3O2S. Mole weight: 345.39.
Vonoprazan Impurity 1
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: N-methyl(5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine fumarate salt. CAS No. 881732-90-7. Molecular formula: C17H17N3O2S. Mole weight: 327.41.
Vonoprazan Impurity 2
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1-(5-(4-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine; 1H-Pyrrole-3-methanamine, 5-(4-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-; SCHEMBL1580664; CHEMBL2079304; 1-[5-(4-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine. CAS No. 881733-36-4. Molecular formula: C17H16FN3O2S. Mole weight: 345.4.
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