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| Product | Description | |
|---|---|---|
| 1-Aminohydantoin hydrochloride | 1-Aminohydantoin hydrochloride is a major metabolite of nitrofurantoin in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat, milk et.al. 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of AHD before detection [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2827-56-7. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-Y0469. |  |
| 1-Chloroacenaphthene | 1-Chloroacenaphthene is a chlorinated derivative of acenaphthene, a polycyclic hydrocarbon that has potential to act as polyploidizing agents in plants. 1-Chloroacenaphthene is a polyaromatic hydrocarbon that is released into the atmosphere by means of incomplete combustion processes (e.g. diesel exhaust). Group: Biochemicals. Grades: Highly Purified. CAS No. 40745-49-1. Pack Sizes: 25mg, 250mg. Molecular Formula: C12H9Cl. US Biological Life Sciences. |  Worldwide |
| 1-Dodecylimidazole | 1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity [1] [2] [3]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: N-Dodecylimidazole. CAS No. 4303-67-7. Pack Sizes: 500 mg; 1 g. Product ID: HY-138540. | |
| 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate - ATTO-700 | ATTO-700, a fluorescent dye widely utilized in biomedical research for protein and cell labeling, boasts exceptional spectral properties. This feature alone renders it invaluable for imaging inquiries, though it offers much more. Employing ATTO-700, researchers have probed into cancer cell glucose uptake, stem cell geographical activity, and the release plus distribution of therapeutic agents. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate, labeled with ATTO 700, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H29N7O10P2- ATTO 700 (free acid). Mole weight: 1088.39 (free acid). |  |
| Alginic Acid | Alginic acid is a tasteless, practically odorless, white to yellowish white, fibrous powder. Synonyms: Acidum alginicum; E400; Kelacid; L-gulo-D-mannoglycuronan; polymannuronic acid; Protacid; Satialgine H8. CAS No. 9005-32-7. Product ID: PE-0139. Molecular formula: (C6H8O)n. Mole weight: 20000 ~ 240000. Category: Stabilizing Agents; Suspending Agents; Sustained Release Agents; Tablet Binder; Tablet Dsintegrant; Viscosity-increasing Agents. Product Keywords: Binder Excipients; Stabilizers; Suspending Agents; ; PE-0139; Alginic Acid; Stabilizing Agents; Suspending Agents; Sustained Release Agents; Tablet Binder; Tablet Dsintegrant; Viscosity-increasing Agents; (C6H8O)n; 9005-32-7. UNII: 8C3Z4148WZ. Chemical Name: Alginic acid. Grade: Pharmceutical Excipients. Administration route: Ophthalmic, oral. Dosage Form: Ophthalmic preparations, oral capsules, and tablets. Stability and Storage Conditions: Alginic acid hydrolyzes slowly at warm temperatures producing a material with a lower molecular weight and lower dispersion viscosity.Alginic acid dispersions are susceptible to microbial spoilage on storage, which may result in some depolymerization and hence a decrease in viscosity. Dispersions should therefore be preserved with an antimicrobial preservative such as benzoic acid; potassium sorbate; sodium benzoate; sorbic acid; or paraben. Concentrations of 0.1-0.2% are usually used. Alginic acid dispersions may be sterilize |  |
| Behenamide | Behenamide is a fatty acid derived from plants such as rapeseed oil and can be synthesized by a variety of processes. Behenamide has unique properties that make it useful as a slip agent, A lubricant and release agent, it is also used in personal care products, including cosmetics and hair care, as a thickener and emollient because of its ability to improve the consistency and texture of formulations. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Docosanamide. CAS No. 3061-75-4. Pack Sizes: 1 g; 5 g. Product ID: HY-W127445. | |
| Bentonite | Bentonite is a crystalline, claylike mineral, and is available as an odorless, pale buff, or cream to grayish-colored fine powder, which is free from grit. It consists of particles about 50-150 mm in size along with numerous particles about 1-2 mm. Microscopic examination of samples stained with alcoholic methylene blue solution reveals strongly stained blue particles. Bentonite may have a slight earthy taste. Synonyms: Albagel; bentonitum; E558; mineral soap; Polargel; soap clay; taylorite; Veegum HS; wilkinite. CAS No. 1302-78-9. Product ID: PE0361. Molecular formula: Al2O3`4SiO2`H2O. Mole weight: 359.16. Category: Adsorbent; Suspending Agents; Thickener; Dairy Stabilizer; Stabilizer. Product Keywords: Suspending Agents; Adsorbents; Stabilizers; ; PE0361; Bentonite; Adsorbent; Suspending Agents; Thickener; Dairy Stabilizer; Stabilizer; Al2O3`4SiO2`H2O; 1302-78-9. UNII: A3N5ZCN45C. Chemical Name: Bentonite. Grade: Pharmceutical Excipients. Administration route: Dental; Oral; Topical; Transdermal. Dosage Form: Oral capsules, tablets, and suspensions, topical suspensions, controlled-release transdermal films, and pessaries. Stability and Storage Conditions: Bentonite is hygroscopic and should avoid absorbing moisture from the environment. The bentonite aqueous suspension can be sterilized by autoclaving. After the solid bentonite was dried at 100°C, it was kept at 170°C for 1 hour for dry heat sterilization. This product | |
| Bombesin | Bombesin is a neuropeptide with many biological effects such as hormone release, activation of pancreatic enzyme secretion, inhibition of gastric emptying and modulation of gastric acid secretion. It binds to the gastrin-releasing peptide receptor (GRPR) in rat pancreatic acinar cells (Ki = 1.88 nM), and also to frog bombesin receptor subtype 4 (BB4) in CHO cells overexpressing the receptor (Ki = 1.7 nM). Uses: Neurotransmitter agents. Synonyms: H-Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2; L-pyroglutamyl-L-glutaminyl-L-arginyl-L-leucyl-glycyl-L-asparagyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valyl-glycyl-L-histidyl-L-leucyl-L-methioninamide; Glp-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH2. Grades: ≥95%. CAS No. 31362-50-2. Molecular formula: C71H110N24O18S. Mole weight: 1619.85. | |
| Carbomer | Carbomers are used as rheology modifiers in liquid or semi-solid pharmaceutical formulations. In tablet formulations, carbomers are used as controlled release agents and/or binders. Synonyms: Carboxypolymethylene resin;Poly(acrylic acid). Grades: 95%. CAS No. 9007-20-9. Molecular formula: C3H4O2. | |
| Carbomer | Carbomers are white-colored, fluffy, acidic, hygroscopic powders with a characteristic slight odor. A granular carbomer is also available (Carbopol 71G). Synonyms: Acrypol; Acritamer; acrylic acid polymer; carbomera; Carbopol; carboxy polymethylene; polyacrylic acid; carboxyvinyl polymer; Pemulen; Tego Carbomer. CAS No. 9003-1-4. Product ID: PE-0469. Category: Bioadhesive Material; Controlled-release Agents; Emulsifying Agents; Emulsion Stabilizer; rheology modifier; Stabilizing Agents; Suspending Agents; Tablet Binder. Product Keywords: Suspending Agents; Emulsifier Excipients; Binder Excipients; ; PE-0469; Carbomer; Bioadhesive Material; Controlled-release Agents; Emulsifying Agents; Emulsion Stabilizer; rheology modifier; Stabilizing Agents; Suspending Agents; Tablet Binder; ; 9003-01-4. UNII: 9G2MAD7J6W. Chemical Name: Carbomer. Grade: Pharmceutical Excipients. Administration route: Oral; ophthalmic, rectal, topical, transdermal ; vaginal. Dosage Form: Oral suspensions, tablets; ophthalmic, rectal, topical, transdermal preparations; vaginal suppositories. Stability and Storage Conditions: Carbomers are stable, hygroscopic materials that may be heated at temperatures for up to 2 hours without affecting their thickening efficiency. However, exposure to excessive temperatures can result in discoloration and reduced stability. Complete decomposition occurs with heating for 30 minutes at 260°C. Dry powder forms of carbomer | |
| Carbomer 941 | Carbomer 941 (CBM 941) is an acrylic acid polymer, which can be used as a thickening agent. Carbomer 941 which forms a high viscosity gel, provides a stable gel matrix, and exhibits good heat, light and microbial contamination resistance. Carbomer 941 facilitates the drug release and local application, which can be used in the pharmaceutical industry [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: CBM 941. CAS No. 9007-20-9. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W250721C. | |
| Carbomer 980 | Carbomer 980 (CBM 980) is an acrylic acid polymer, which can be used as a thickening agent. Carbomer 980 provides a stable gel matrix, exhibits good heat, light and microbial contamination resistance. Carbomer 980 facilitates the drug release and local application, which can be used in the pharmaceutical industry [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: CBM 980. CAS No. 9007-20-9. Pack Sizes: 25 g. Product ID: HY-W250721. | |
| Carrageenan | Carrageenan, when extracted from the appropriate seaweed source, is a yellow-brown to white colored, coarse to fine powder that is odorless and tasteless. Synonyms: Chondrus extract; E407; Gelcarin; Genu; Grindsted; Hygum TP-1; Irish moss extract; Marine Colloids; SeaSpen PF; Viscarin. Product ID: PE-0639. Category: Emulsifying Agents; Stabilizing Agents; Suspending Agents; Sustained-release Agents; Viscosity-increasing Agents. Product Keywords: Excipients for Liquid Dosage Form; Suspending Agents; PE-0639; Carrageenan; Emulsifying Agents; Stabilizing Agents; Suspending Agents; Sustained-release Agents; Viscosity-increasing Agents;. UNII: 5C69YCD2YJ. Grade: Pharmceutical Excipients. Stability and Storage Conditions: Carrageenan is a stable, though hygroscopic, polysaccharide and should be stored in a cool, dry place. Carrageenan in solution has maximum stability at pH 9 and should not be heat processed at pH values below 3.5. Acid and oxidizing agents may hydrolyze carrageenan in solution leading to loss of physical properties through cleavage of glycosidic bonds. Acid hydrolysis depends on pH, temperature and time. The acid hydrolysis takes place only when the carrageenan is dissolved, and the hydrolysis is accelerated as the processing temperature and/or the processing time is increased. However, when the carrageenan is in its gelled state the acid hydrolysis no longer takes place. Source and Preparation: The main sp | |
| Ceratonia | Ceratonia occurs as a yellow-green or white colored powder. Although odorless and tasteless in the dry powder form, ceratonia acquires a leguminous taste when boiled in water. Synonyms: Algaroba; carob bean gum; carob flour; ceratonia gum; ceratonia siliqua; ceratonia siliqua gum; Cheshire gum; E410; gomme de caroube; locust bean gum; Meyprofleur; St Johns bread. CAS No. 9000-40-2. Product ID: PE-0468. Category: Controlled-release Agents; Stabilizing Agents; Suspending Agents; Tablet Binder; Viscosity-increasing Agents. Product Keywords: Binder Excipients; Stabilizers; Suspending Agents; ; PE-0468; Ceratonia; Controlled-release Agents; Stabilizing Agents; Suspending Agents; Tablet Binder; Viscosity-increasing Agents; ; 9000-40-2. UNII: V4716MY704. Chemical Name: Carob gum. Grade: Pharmceutical Excipients. Administration route: Oral. Dosage Form: oral tablet. Stability and Storage Conditions: The bulk material should be stored in a well-closed container in a cool, dry place. Ceratonia loses not more than 15% of its weight on drying. Source and Preparation: Ceratonia is a naturally occurring material obtained from the ground endosperms separated from the seeds of the locust bean tree, Ceratonia siliqua (Leguminosae). The tree is indigenous to southern Europe and the Mediterranean region. Applications: Ceratonia is a naturally occurring material generally used as a substitute for tragacanth or other similar gums. A ceratoni | |
| Ceritinib | An anaplastic lymphoma kinase (ALK)-positive inhibitor used for the treatment of non-small cell lung cancer (NSCLC). It less potently inhibits IGF-1R, InsR, and STK22D and IC50 value is 8, 7, and 23 nM. LDK378 is also minimally effective against a panel of other kinases. In Sep 2016, Interim adverse events and efficacy data from phase III ASCEND-4 trial in non small cell lung cancer released by Novartis. In Oct 2016, efficacy data from the phase III ASCEND-3 and ASCEND-5 trial in non small cell lung cancer was presented. Uses: Antineoplastic agents. Synonyms: 5-Chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine, LDK-378, LDK378; LDK 378; Zykadia; NVP-LDK378-NX. Grades: ≥98%. CAS No. 1032900-25-6. Molecular formula: C28H36ClN5O3S. Mole weight: 558.14. | |
| Clove Oil | Clove Oil. Synonyms: Clove Bud Oil. CAS No. 8000-34-8. Product ID: PE-0414. Category: Flavoring agent. Product Keywords: Pharmaceutical Excipients; Excipients for Liquid Dosage Form; Clove Oil; Corrective Agents; Flavoring agent; /; 8000-34-8; 8000-34-8. UNII: 578389D6D0. Grade: Pharmceutical Excipients. Administration route: Oral; Dentistry (as toothpaste ingredient). Dosage Form: Toothpaste, elixir and suspension. Stability and Storage Conditions: Flammable, fire site release spicy stimulating smoke, easy to be oxidized, so should be sealed, shading, stored in a cool, dry place, away from the source of fire, heat and oxidant. Commonly used amount and the maximum amount: General dosage 3-1800mg/kg. Source and Preparation: An essential oil obtained by steam distillation from the dried flower buds of Eugenia caryophyllate or E. aromatica, a plant in the myrtle family. Its main components are eugenol (70%-90%), eugenol ethyl acetate (10%-15%), caryophyllene (5%-12%), methylamyl protanol, methylheptyl protanol, methylamyl ketone and ylenene, etc. Safety: This product is generally considered safe. | |
| Diazoxide | Diazoxide is a potassium channel activator that causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. The cellular release of potassium switches off voltage-gated calcium ion channels which inhibits the generation of an action potential. Uses: Antihypertensive agents. Synonyms: 7-Chloro-3-methyl-4H-1,2,4-benzothiadiazine 1,1-dioxide. Grades: 98% (TLC). CAS No. 364-98-7. Molecular formula: C8H7ClN2O2S. Mole weight: 230.7. | |
| Dimethyl sulfoxide | Dimethyl sulfoxide (DMSO) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity [1]. Low endotoxin, can be used in various biochemical experiments such as drug dissolution. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DMSO. CAS No. 67-68-5. Pack Sizes: 100 mL; 200 mL; 500 mL. Product ID: HY-Y0320C. | |
| Dimethyl sulfoxide, meets analytical specification of Ch.P. | Dimethyl sulfoxide (DMSO), meets analytical specification of Ch.P. is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties [1] [2] [3]. MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition). Amicrobic, low endotoxin, can be used in various biochemical experiments such as drug dissolution. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: DMSO, meets analytical specification of Ch.P. CAS No. 67-68-5. Pack Sizes: 10 mL; 100 mL; 200 mL; 500 mL. Product ID: HY-Y0320. | |
| D-Val-Leu-Lys 4-nitroanilide dihydrochloride | D-Val-Leu-Lys 4-nitroanilide dihydrochloride stands as a crucial substrate to gauge the efficiency of trypsin-like serine proteases. Proteolysis event leads to the release of a yellow colored product, whose quantification can be done at 405 nm. Its utility can be seen in trypsin activity detection and the evaluation of agents restricting trypsin-like proteases. Consistent usage of this product aids in experimental design and the analysis of diverse protease substrates. Synonyms: (S)-6-Amino-2-((S)-2-((R)-2-amino-3-methylbutanamido)-4-methylpentanamido)-N-(4-nitrophenyl)hexanamide dihydrochloride; H-D-Val-Leu-Lys-pNA 2HCl. CAS No. 62354-43-2. Molecular formula: C23H40Cl2N6O5. Mole weight: 551.5. | |
| Etofibrate | Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations. Uses: Anticholesteremic agents. Synonyms: ethofibrate; Etofibrato; 3-Pyridinecarboxylic acid, 2-[2-(4-chlorophenoxy)-2-methyl-1-oxopropoxy]ethyl ester; Lipo-Merz; Tricerol. Grades: >98%. CAS No. 31637-97-5. Molecular formula: C18H18ClNO5. Mole weight: 363.79. | |
| Glyceryl Monooleate | Glyceryl Monooleate. Synonyms: Glycerol Mono-oleate(BP); Aldo MO; Atlas G-695; Capmul GMO; glycerol-1-oleate; glyceroli mono-oleas; glyceryl mono-oleate; HallStar GMO; Imwitor 948; Kessco GMO; Ligalub; monolein; Monomuls 90-O18; mono-olein; a-mono-olein glycerol; Peceol; Priolube 1408; Stepan GMO; Tegin. CAS No. 25496-72-4. Product ID: PE-0572. Molecular formula: C21H40O4. Mole weight: 356.55. Category: Bioadhesive Material; Emollient; Emulsifier; Emulsion Stabilizer; Gelling Agents; Nonionic Surfactant; Continuous Release Agents. Product Keywords: Stabilizers; Emulsifier Excipients; Surfactant Excipients; ; PE-0572; Glyceryl Monooleate; Bioadhesive Material; Emollient; Emulsifier; Emulsion Stabilizer; Gelling Agents; Nonionic Surfactant; Continuous Release Agents; C21H40O4; 25496-72-4. UNII: C4YAD5F5G6. Chemical Name: 9-Octadecenoic acid (Z), monoester with 1, 2, 3-propanetriol. Grade: Pharmceutical Excipients. Administration route: Oral; Topical. Dosage Form: Soluble film. Stability and Storage Conditions: Monoolein should be stored in an airtight container in a cool, dry place away from light. Commonly used amount and the maximum amount: When used as emulsifier or cosolvent in topical preparations, the maximum dosage is generally 5mg/g. Source and Preparation: Monooleic glycerides are produced by the ester of fatty acids, mainly oleic acids, with glycerides. Since fatty acids are not pure substances but mixt | |
| Glyceryl Monostearate | While the names glyceryl monostearate and mono- and diglycerides are used for a variety of esters of long-chain fatty acids, the esters fall into two distinct grades: 40-55 percent monoglycerides The PhEur describes glyceryl monostearate 40-55 as a mixture of monoacylglycerols, mostly monostearoylglycerol, together with quantities of di- and triacylglycerols. It contains 40-55% of monoacylglycerols, 30-45% of diacylglycerols, and 5-15% of triacylglycerols. Synonyms: Capmul GMS-50; Cutina GMS; 2, 3-dihydroxypropyl octadecanoate; Geleol; glycerine monostearate; glycerin monostearate; glycerol monostearate; glyceroli monostearas; glycerol stearate; glyceryl stearate; GMS; HallStar GMS; Imwitor 191; Imwitor 900; Kessco GMS; Lipo GMS; monoester with 1, 2, 3-propanetriol; monostearin; Myvaplex 600P; Myvatex; 1, 2, 3-propanetriol octadecanoate; Protachem GMS-450; Ri. CAS No. 31566-31-1. Product ID: PE-0518. Molecular formula: C21H42O4. Mole weight: 358.6. Category: Emollient; Emulsifying Agents; Solubilizing Agents; Stabilizing Agents; Sustained-release Agents; Tablet and Capsule Lubricant. Product Keywords: Emulsifier Excipients; Solubilizer Excipients; PE-0518; Glyceryl Monostearate; Emollient; Emulsifying Agents; Solubilizing Agents; Stabilizing Agents; Sustained-release Agents; Tablet and Capsule Lubricant; C21H42O4; 31566-31-1. UNII: NA. Chemical Name: Octadecanoic acid, monoester with 1, 2, 3-propanetriol. Gra | |
| Hymetellose328 | Hymetellose328. Synonyms: Methylhydroxyethylcellulose; Cellulose; 2-hydroxyethyl methyl ether; HEMC; Tyopur MH. CAS No. 9032-42-2. Product ID: PE-0540. Molecular formula: C2H6O2·xCH4O·x. Category: Pore-forming Agents; Coating Agents; Thickener; Suspending Agents; Dispersing Agents; Binding Agents; Emulsifier; Film-forming Agents; Water-retaining Agents. Product Keywords: Excipients for Liquid Dosage Form; Emulsifier Excipients; PE-0540; Hymetellose328; Pore-forming Agents; Coating Agents; Thickener; Suspending Agents; Dispersing Agents; Binding Agents; Emulsifier; Film-forming Agents; Water-retaining Agents; C2H6O2·xCH4O·x; 9032-42-2. UNII: 0MGW7Q3QG4. Chemical Name: Hydroymethylmethylecellulose. Grade: Pharmceutical Excipients. Administration route: Oral, optical. Dosage Form: Oral suspensions, tablets and topical formulations. Stability and Storage Conditions: Hydroxymethylcellulose is hygroscopic and should be stored in a cool, dry place. Applications: 1.Pharmacy As a hydrophilic gel matrix material, porogen, and coating agent for the preparation of sustained-release preparations. It can also be used as a thickening, suspending, dispersing, binding, emulsifying, film-forming, and water-retaining agent for preparations. 2. Food processing can also be used as, adhesive, emulsifying, film-forming, thickening, suspending, dispersing, water-retaining agent, etc. 3. In the daily chemical industry, it is used as an addi | |
| Hypromellose | Hypromellose. Synonyms: Benecel MHPC; E464; hydroxypropyl methylcellulose; HPMC; hypromellosum; Methocel; methylcellulose propylene glycol ether; methyl hydroxypropylcellulose; Metolose; MHPC; Pharmacoat; Tylopur; Tylose MO. CAS No. 9004-65-3. Product ID: PE-0206. Category: Bioadhesive Material; Coating Agents; Controlled-release Agents; dispersing Agents; Emulsifying Agents; Emulsion Stabilizer; extended-release Agents; Film-forming Agents; foaming Agents; Granulation Aid; modified-release Agents; mucoadhesive. Product Keywords: Coating Systems Excipients; Emulsifier Excipients; Suspending Agents; ; PE-0206; Hypromellose; Bioadhesive Material; Coating Agents; Controlled-release Agents; dispersing Agents; Emulsifying Agents; Emulsion Stabilizer; extended-release Agents; Film-forming Agents; foaming Agents; Granulation Aid; modified-release Agents; mucoadhesive; 9004-65-3. UNII: B1QE5P712K. Chemical Name: Cellulose hydroxypropyl methyl ether. Grade: Pharmceutical Excipients. Administration route: Ophthalmic and nasal; oral. Dosage Form: Ophthalmic and nasal preparations; oral capsules, suspensions, syrups, and tablets. Stability and Storage Conditions: Hypromellose powder is a stable material, although it is hygroscopic after drying. Solutions are stable at pH 3-11. Hypromellose undergoes a reversible sol-gel transformation upon heating and cooling, respectively. The gelation temperature is 50-90°C, depending upon the g | |
| Hypromellose Acetate Succinate | Hypromellose acetate succinate is a white to off-white powder or granules. It has a faint acetic acid-like odor and a barely detectable taste. Hypromellose acetate succinate is available in several grades, according to the pH at which the polymer dissolves (low, L; medium, M; and high, H) and its predominant particle size (cohesive fine powder, F; or free-flowing granules, G). Synonyms: Aqoat; Aqoat AS-HF/HG; Aqoat AS-LF/LG; Aqoat AS-MF/MG; cellulose, 2-hydroxypropyl methyl ether, acetate succinate; HPMCAS. CAS No. 71138-97-1. Product ID: PE-0594. Category: Controlled-release Agents; Coating Agents; Film-forming Agents; Sustained-release Agents. Product Keywords: Excipients for Liquid Dosage Form; Solubilizer Excipients; PE-0594; Hypromellose Acetate Succinate; Controlled-release Agents; Coating Agents; Film-forming Agents; Sustained-release Agents; ; 71138-97-1. UNII: NA. Chemical Name: Cellulose, 2-hydroxypropylmethyl ether, acetate hydrogen butanedioate. Grade: Pharmceutical Excipients. Administration route: Oral. Dosage Form: Capsules, and delayed-action preparations. Stability and Storage Conditions: Hypromellose acetate succinate should be stored in a well-closed container, in a cool, dry place. In such storage conditions, hypromellose acetate succinate is a stable material. Hypromellose acetate succinate is hygroscopic. It is hydrolyzed to acetic acid and succinic acid, and the hypromellose po | |
| Ipsapirone | Ipsapirone is a selective partial agonist of the serotonin (5-HT) receptor 5-HT1A. Its Ki value is 10 nM in hippocampal membranes. It reduces 5-HT release in rat ventral hippocampus in vivo. It also inhibits passive avoidance behavior and foot shock-induced aggression in rats. It has anxiolytic effects in vivo. It has been used to treat borderline personality disorder and depression. Uses: Anti-anxiety agents. Synonyms: TVX Q 7821; 1,1-Dioxo-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-1,2-benzothiazol-3-one; 2-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3(2H)-one-1,1-dioxide. Grades: ≥99% by HPLC. CAS No. 95847-70-4. Molecular formula: C19H23N5O3S. Mole weight: 401.48. | |
| Lck Inhibitor | Lck Inhibitor is a small-molecule inhibitor. It takes participate in the T-cell receptor (TCR) signal transduction and affects the expression of genes associated with cell proliferation, cytokine release and T-cell survival. It has been designed and developed as therapeutic agents for the treatment for T-cell-mediated autoimmune and organ transplant rejection. It showed high selectivity against Lck over another Src family kinase Src and the kinases. It also showed more than 1000-fold greater selectivity over CDK, MAPK and the RSK family. Synonyms: TC-S 7003; TC S 7003; TCS 7003; TC-S-7003; TCS7003; TCS-7003. Grades: >98%. CAS No. 847950-09-8. Molecular formula: C31H30N8O. Mole weight: 530.62. | |
| Miriplatin hydrate | Miriplatin (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC). Miriplatin is a lipophilic platinum complex that can be easily suspended in Lipiodol and gradually releases active platinum compounds in tumor tissue. Miriplatin is less severe toxicity profile compared to other platinum anticancer agents. Synonyms: Miripla; Miriplatin; SM 11355; SM11355; SM-11355; MTP. Grades: >98%. CAS No. 250159-48-9. Molecular formula: C34H70N2O5Pt. Mole weight: 782.01. | |
| Nidulin (Methylustin) | Nidulin is a depsidone produced by several fungal species with potent and selective antibacterial activity. While literature relating to nidulin is limited, it is closely related to folipasatin and unguinol identified as inhibitors of phospholipase A2, arachidonic acid release from rat polymorphonuclear leukocytes and nitrendipine binding to porcine heart membrane. While showing some calcium blocking attributes these metabolites have potential as antiinflammatory agents. Group: Biochemicals. Alternative Names: Methylustin. Grades: Highly Purified. CAS No. 10089-10-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Nornidulin (Ustin) | Nornidulin is a depsidone produced by several fungal species with potent and selective antibacterial activity. While literature on nornidulin is limited, it is closely related to folipasatin and unguinol identified as inhibitors of phospholipase A2, arachidonic acid release from rat polymorphonuclear leukocytes and nitrendipine binding to porcine heart membrane. While showing some calcium blocking attributes both metabolites have potential as antiinflammatory agents. Group: Biochemicals. Alternative Names: Ustin. Grades: Highly Purified. CAS No. 33403-37-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| NPS-2143 hydrochloride | NPS-2143 (SB-262,470A) is a calcilytic drug which acts as an antagonist at the Calcium-sensing receptor (CaSR), and consequently stimulates release of parathyroid hormone. Calcilytic drugs have been researched as potential treatments for osteoporosis, and as the first such compound developed, NPS-2143 is still widely used in research into the CaSR receptor as well as design of newer calcilytic agents. Synonyms: NPS2143 hydrochloride; NPS 2143 hydrochloride. Grades: >98%. CAS No. 324523-20-8. Molecular formula: C24H26Cl2N2O2. Mole weight: 445.38. | |
| Oleyl Alcohol | Oleyl alcohol occurs as a pale yellow oily liquid that gives off acrid fumes when heated. Synonyms: Alcohol oleicus; HD-Eutanol V PH; Novol; Ocenol; cis-9- octadecen-1-ol; oleic alcohol; oleo alcohol; oleol. CAS No. 143-28-2. Product ID: PE-0555. Molecular formula: C18H36O. Mole weight: 268.48. Category: Antifoaming Agents; emollient; EmulsifyingAgents; Skin Penetrant; Sustained-release Agents. Product Keywords: Excipients for Liquid Dosage Form; Emulsifier Excipients; PE-0555; Oleyl Alcohol; Antifoaming Agents; emollient; EmulsifyingAgents; Skin Penetrant; Sustained-release Agents; C18H36O; 143-28-2. UNII: 172F2WN8DV. Chemical Name: (Z)-9-Octadecen-1-ol. Grade: Pharmceutical Excipients. Administration route: Topical. Dosage Form: Topical emulsions and ointments. Stability and Storage Conditions: The bulk material should be stored in a well-closed container in a cool, dry, place. Source and Preparation: Oleyl alcohol occurs naturally in fish oils. Synthetically, it can be prepared from butyl oleate by a Bouveault-Blanc reduction with sodium and butyl alcohol. An alternative method of manufacture is by the hydrogenation of triolein in the presence of zinc chromite. Applications: Oleyl alcohol is mainly used in topical pharmaceutical formulations and has been used in transdermal delivery formulations.It has been utilized in the development of biodegradable injectable thermoplastic oligomers, and in aerosol formulations | |
| Pectin | Pectin occurs as a coarse or fine, yellowish-white, odorless powder that has a mucilaginous taste. CAS No. 9000-65-5. Product ID: PE0363. Mole weight: 30000~100000. Category: Adsorbent; Excipient; Emulsifier; Gelling Agents; Thickener; Stabilizer (Emulsion); Sustained release drug delivery material; Used to prepare controlled release mixed polymer microsphere system. Product Keywords: Stabilizers; Emulsifier Excipients; Adsorbents; ; PE0363; Pectin; Adsorbent; Excipient; Emulsifier; Gelling Agents; Thickener; Stabilizer (Emulsion); Sustained release drug delivery material; Used to prepare controlled release mixed polymer microsphere system; ; 9000-65-5. UNII: 89NA02M4RX. Chemical Name: Pectin. Grade: Pharmceutical Excipients. Administration route: Oral, Dental, Topical, Nasal. Dosage Form: Paste, Spray, Capsule, extended release, Powder, Tablet. Stability and Storage Conditions: Pectin is a stable excipient, and this product should be placed in an airtight container. Store in a cool, dry place. Commonly used amount and the maximum amount: The maximum dosage for oral administration: 60.06mg; the maximum dosage for general topical application: 260mg/g; the maximum dosage for dental topical and oral use: 170mg/g. Source and Preparation: Pectin is obtained by diluting the acidic extracts of citrus peels or apple pomace. Applications: It can be used as adsorbent, emulsifier, gelling agent, thickener and stabilizer. Pectin can be | |
| Poly(acrylic acid) partial sodium salt solution | Sodium salt of poly(acrylic acid) is a superabsorbent polymer. Superabsorbents are composed of crosslinked networks of hydrophilic polymers. It can absorb and retain a large capacity of water based fluids, the release of the absorbed fluids is tough even under an applied pressure. Absorption capacity is inversely proportional to salt concentration and applied load.They are formed via solution or inverse-suspension polymerization techniques. . Uses: Sodium salt of poly (acrylic acid) may be used as a major component of non glare coatings for headlights.it acts as an antiscaling agents.it's effect of the salt on the crystal (cu and ms metals) formation was studied. general s of these superabsorbents are in many fields such as agriculture and horticulture, sanitary goods, sealing composites, component of moisture barrier tapes and coatings, humidity control, gel actuators. and medicine for drug-delivery systems. Group: Hydrogels and crosslinked polymershydrophilic polymers. Alternative Names: Acrylic acid-sodium acrylate copolymer, Sodium acrylate-acrylic acid copolymer. CAS No. 9033-79-8. Pack Sizes: Packaging 250 g in poly bottle. Molecular formula: average Mw ~2,000 by GPC. |  |
| Polycarbophil | Polycarbophil occurs as fluffy, white to off-white, mildly acidic polymer powder with slightly acetic odor. Synonyms: Noveon AA-1. CAS No. 9003-97-8. Product ID: PE0366. Category: Adsorbents; Controlled-release agents; Suspending agents; Binders; Thickeners. Product Keywords: Pharmaceutical Excipients; Excipients for Solid Dosage Form; Filler Excipients; Absorbent; Polycarbophil; PE0366; W25LM17A4W; 9003-97-8; 9003-97-8. UNII: W25LM17A4W. Chemical Name: Polycarbophil. Grade: Pharmceutical Excipients. Administration route: Buccal; Ophhalmic; Topical. Dosage Form: Film; Tablet; Gel; Solution; Suspension/Drops. Stability and Storage Conditions: Polycarbophil polymers are stable, hygroscopic materials. They do not undergo hydrolysis or oxidation under normal conditions. ners necessitates a pH greater than 7.7 to prolong polycarbophil stability. Applications: Conventionally, polycarbophil is used as a thickening agent at very low concentrations (less than 1%) to produce a wide range of viscosities and flow properties in topical lotions, creams, and gels, in oral suspensions, and in transdermal gel reservoirs. It is also used as an emulsifying agent in topical oil-in-water systems. Polycarbophil is an excellent bioadhesive in buccal, ophthalmic, intestinal, nasal, vaginal, and rectal applications. Buccal tablets prepared using polycarbophil have shown high bioadhesive force and prolonged residence time, and proved to be no | |
| Polycarbophil | Polycarbophil occurs as fluffy, white to off-white, mildly acidic polymer powder with slightly acetic odor. Synonyms: Noveon AA-1. CAS No. 9003-97-8. Product ID: PE-0565. Category: Adsorbent; Bioadhesive Material; Controlled-release Agents; Emulsifying Agents; Suspending Agents; Tablet Binder; Thickening Agents. Product Keywords: Excipients for Liquid Dosage Form; Emulsifier Excipients; PE-0565; Polycarbophil; Adsorbent; Bioadhesive Material; Controlled-release Agents; Emulsifying Agents; Suspending Agents; Tablet Binder; Thickening Agents; ; 9003-97-8. UNII: W25LM17A4W. Chemical Name: Polycarbophil. Grade: Pharmceutical Excipients. Administration route: Buccal; Ophhalmic; Topical. Dosage Form: Film; Tablet; Gel; Solution; Suspension/Drops. Stability and Storage Conditions: Polycarbophil polymers are stable, hygroscopic materials. They do not undergo hydrolysis or oxidation under normal conditions. Heat aging at temperatures for up to 2 hours does not affect the efficiency of the dry polymer. However, prolonged exposure to excessive temperatures can result in discoloration, reduced stability, and in some cases plasticization of the polymer. Applications: Conventionally, polycarbophil is used as a thickening agent at very low concentrations (less than 1%) to produce a wide range of viscosities and flow properties in topical lotions, creams, and gels, in oral suspensions, and in transdermal gel reservoirs. It is also u | |
| Poly(D,L-lactide-co-glycolide) (65:35) | Controlled release of bioactive agents, sutures and bioabsorbable implantable devices. Synonyms: PLGA. Product ID: MSMN-027. Category: Raw Materials. | |
| Poly(ethylene glycol) methyl ether-block-poly(lactide-co-glycolide) | Contains ≤500 ppm impurities by GC, including trace monomer and residual organics. Uses: Biocompatible block copolymer. can be used in the formation of nanoparticles for drug delivery. potential use in the targeted and/or controlled release of cancer drugs, anti-inflammatory drugs, antibiotics, or anesthetic agents. Group: Biodegradable polymerspoly(ethylene glycol) and poly(ethylene oxide). Alternative Names: PEG-PLGA, mPEG-b-PLGA. Molecular formula: PEG average Mn 5,000 PLGA Mn 5,000. Mole weight: H[(C3H4O2)x(C2H2O2)y]mO[C2H4O]nCH3. | |
| Polyoxylglycerides | Polyoxylglycerides are inert liquid or semi-solid waxy materials and are amphiphilic in character. Caprylocaproyl polyoxylglycerides are pale-yellow oily liquids. Lauroyl polyoxylglycerides and stearoyl polyoxylglycerides occur as pale-yellow waxy solids. Oleoyl polyoxylglycerides and linoleoyl polyoxylglycerides occur as amber oily liquids, which may give rise to a deposit after prolonged periods at 20°C. Synonyms: Polyoxylglycerides are referred to as macrogolglycerides in Europe. Product ID: PE-0562. Category: Emulsifying Agents; Nonionic Surfactant; Penetration Agents; Solubilizing Agents; Sustained-release Agents. Product Keywords: Stabilizers; Emulsifier Excipients; Surfactant Excipients; ; PE-0562; Polyoxylglycerides; Emulsifying Agents; Nonionic Surfactant; Penetration Agents; Solubilizing Agents; Sustained-release Agents. UNII: NA. Grade: Pharmceutical Excipients. Administration route: Oral; topical; vaginal. Dosage Form: Oral route: capsules, tablets, solutions; topical route: emulsions, creams, lotions; vaginal route: emulsions, creams. Stability and Storage Conditions: Polyoxylglycerides are very stable and inert. However, preventive measures against the risk of oxidation or hydrolysis may be taken to ensure stability during handling. Polyoxylglycerides should be preserved in their original containers, and exposure to air, light, heat, and moisture should be prevented. Source and Preparation: Polyoxyl | |
| Powdered Cellulose | Powdered cellulose occurs as a white or almost white, odorless and tasteless powder of various particle sizes, ranging from a freeflowing fine or granular dense powder, to a coarse, fluffy, nonflowing material. Synonyms: Cellulose, Powdered; Alpha-cellulose; Arbocel; cellulosi pulvis; E460; Elcema; KC Flock; Microcel 3E-150; Sanacel; Sanacel Pharma; Sancel-W; Solka-Floc. CAS No. 9004-34-6. Product ID: PE0367. Molecular formula: (C6H10O5)n, n?500. Mole weight: ?243 000 Since cellulose is extracted from natural polymers, the chain lengths can vary, as can the molecular weight. Category: Adsorbents; Glidants; Suspending Agentss; Diluents; Disintegrating Agentss. Product Keywords: Suspending Agents; Adsorbents; PE0367; Powdered Cellulose; Adsorbents; Glidants; Suspending Agentss; Diluents; Disintegrating Agentss; (C6H10O5)n, n?500; 9004-34-6. UNII: SMD1X3XO9M. Chemical Name: Cellulose. Grade: Pharmceutical Excipients. Administration route: Oral; Dental; Sublingual; Oral; Topical. Dosage Form: Toothpaste, tablets (including sustained and controlled release preparations, etc.), capsules, drops, dry suspensions, etc. Stability and Storage Conditions: Powdered cellulose is a stable, slightly hygroscopic substance; it should be kept in an airtight container in a cool, dry place. Commonly used amount and the maximum amount: Capsule filler: 0~100%; tablet binder: 5%~25%; tablet disintegrant: 5%~15%; tablet glidant: 1%~2%. | |
| S18986 ((S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide, (S)-2,3,3a,4-tetrahydro-1H-benzo[e]pyrrolo[2,1-c][1,2,4]thiadiazine 5,5-dioxide, AMPA Receptor Positive Allosteric Modulator, S18986) | A positive allosteric modulator selective for the AMPA receptors. A nootropic and neuroprotective agents frequently used in researches studying cognition, memory, and aging related cognitive declines. Induces production of BNDF and AMPA-mediated release of noradrenaline and acetylcholine. Biologically viable admitted systematically. Group: Biochemicals. Grades: Highly Purified. CAS No. 175340-20-2. Pack Sizes: 5mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences. | Worldwide |
| SGI-110 | SGI-110 is a dinucleotide antimetabolite of a decitabine linked via phosphodiester bond to a guanosine, with potential antineoplastic activity. Following metabolic activation by phosphorylation and incorporation into DNA, SGI-110 inhibits DNA methyltransferase, thereby causing genome-wide and non-specific hypomethylation and inducing cell cycle arrest at S-phase. This agent is resistant to cytidine deaminase, hence may result in gradual release of decitabine both extra- and intracellularly, leading to more prolonged exposures to decitabine. Uses: Antineoplastic agents. Synonyms: Guadecitabine; SGI 110; SGI110; 2'-deoxy-5-azacytidylyl-(3'->5')-2'-deoxyguanosine; (2R,3S,5R)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl (((2R,3S,5R)-5-(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl) hydrogen phosphate. Grades: ≥95%. CAS No. 929901-49-5. Molecular formula: C18H24N9O10P. Mole weight: 557.41. | |
| Shellac | Shellac. Synonyms: Shellac Flake;(5ξ,10β)-10,14-Dihydroxycedr-8-ene-12,15-dioic acid - 9,10,15-trihydroxypentadecanoic acid (1:1);SHELLAC GUM, ORANGE;SHELLAC ORANGE;Shellac;SHELLAC WAX-FREE, PH EUR;SHELLAC ORANGE BEST QUALITY;Schellack. CAS No. 9000-59-3. Pack Sizes: 1 kg. Product ID: CDF4-0015. Category: Coating Agents. Product Keywords: Food Ingredients; Coating Agents; Shellac; CDF4-0015; 9000-59-3; 232-549-9; 9000-59-3. Purity: 0.99. EC Number: 232-549-9. Solubility: Practically insoluble in water, gives a more or less opalescent solution (wax containing shellac and bleached shellac) or a clear solution (dewaxed shellac and bleached, dewaxed shellac) in anhydrous ethanol. When warmed it is sparingly soluble or soluble in alkaline solutions. Storage: 2-8°C. Application: Shellac is used in the preparation of cosmetic products such as mascara and acrylic nail products. It is also used in the formulation of aqueous-core capsules for riboflavin release. Melting Point: 115-120°. Density: 1.035-1.140. | |
| Sipatrigine | Sipatrigine is a blocker of voltage-dependent sodium channels (NaV) and a glutamate release inhibitor. Sipatrigine exhibits neuroprotective activity in rat models of cerebral ischemia. It was also reported to block Ca2+ channels. Uses: Neuroprotective agents. Synonyms: 619C; 619C-89; BW-619C-89; BW-619C89; 619 C; 619C 89; BW 619C-89; BW 619C89; 619C; 619C89; BW619C89; 2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine. Grades: ≥99% by HPLC. CAS No. 130800-90-7. Molecular formula: C15H16Cl3N5. Mole weight: 372.68. | |
| Sodium Alginate | Sodium alginate occurs as an odorless and tasteless, white to pale yellowish-brown colored powder. Synonyms: Alginato sodico; algin; alginic acid, sodium salt; E401; Kelcosol; Keltone; natrii alginas; Protanal; sodium polymannuronate. CAS No. 9005-38-3. Product ID: PE-0111. Category: Stabilizing Agents; Suspending Agents; Tablet and Capsule Disintegrant; Tablet Binder; Viscosity Increasing Agents. Product Keywords: Emulsifier Excipients; Emulsifier & Suspending Agents; Binder Excipients; Suspending Agents; PE-0111; Sodium Alginate; Stabilizing Agents; Suspending Agents; Tablet and Capsule Disintegrant; Tablet Binder; Viscosity Increasing Agents; ; 9005-38-3. UNII: C269C4G2ZQ. Chemical Name: Sodium alginate. Grade: Pharmceutical Excipients. Administration route: Oral. Dosage Form: Oral suspensions and tablets, oral capsules, modified release tablets, enteric-coated tablets and lozenges. Stability and Storage Conditions: Sodium alginate is a hygroscopic material, although it is stable if stored at low relative humidities and a cool temperature. Aqueous solutions of sodium alginate are most stable at pH 4-10. Below pH 3, alginic acid is precipitated. A 1% w/v aqueous solution of sodium alginate exposed to differing temperatures had a viscosity 60-80% of its original value after storage for 2 years.Solutions should not be stored in metal containers. Sodium alginate solutions are susceptible on storage to microbial spoi | |
| Taltirelin Hydrate | Taltirelin hydrate is a thyrotropin-releasing hormone receptor (TRH-R) superagonist with an IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release). Uses: Nootropic agents. Synonyms: N-{[(4S)-1-methyl-2,6-dioxohexahydropyrimidin-4-yl]carbonyl}-L-histidyl-L-prolinamide tetrahydrate; (S)-N-[(Hexahydro-1-methyl-2,6-dioxo-4-pyrimidinyl)carbonyl]-L-histidyl-L-prolinamide tetrahydrate; Ceredist tetrahydrate; TA 0910 tetrahydrate; (S)-N-((S)-1-((S)-2-Carbamoylpyrrolidin-1-yl)-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxamide tetrahydrate; 1-methyl-(S)-4,5-dihydroorotyl-L-histidyl-L-prolinamide tetrahydrate. Grades: ≥95%. CAS No. 201677-75-0. Molecular formula: C17H31N7O9. Mole weight: 477.46. | |
| Tiaramide hydrochloride | Tiaramide is an anti-inflammatory drug that inhibits the action of mediators released from mast cells and has direct smooth muscle relaxant properties. It is commonly used in the treatment of asthma. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: 2(3H)-Benzothiazolone, 5-chloro-3-[2-[4-(2-hydroxyethyl)-1-piperazinyl]-2-oxoethyl]-, hydrochloride (1:1); 1-Piperazineethanol, 4-[(5-chloro-2-oxo-3(2H)-benzothiazolyl)acetyl]-, monohydrochloride; FK 1160; NSC 289337; NTA 194; RHC 2592; Solantal. Grades: ≥95%. CAS No. 35941-71-0. Molecular formula: C15H19Cl2N3O3S. Mole weight: 392.30. | |
| TPCS2a | TPCS2a, also know as, tetraphenyl chlorin disulfonate, is a meso-tetraphenylchlorin substituted by two adjacent sulfonated groups with potential photosensitizing activity. Upon administration, tetraphenyl chlorin disulfonate incorporates into the cell endosome and lysosome membranes. Subsequently, cytotoxic agents are administered and accumulate in endosomal and lysosomal compartments; upon local activation by light, tetraphenyl chlorin disulfonate produces reactive oxygen species (ROS), such as singlet oxygen, damaging endo/lysosomal membranes and accumulated cytotoxic agents are released into the tumor cell cytosol. This photochemical internalization (PCI) method can enhance the efficacy and selectivity of cytotoxic agents. Synonyms: Benzenesulfonic acid, 4,4'-(7,8-dihydro-15,20-diphenyl-21H,23H-porphine-5,10-diyl)bis-; 4,4'-(7,8-Dihydro-15,20-diphenyl-21H,23H-porphine-5,10-diyl)bis[benzenesulfonic acid]; Amphinex; Di(monoethanolammonium) meso-tetraphenyl chlorin disulfonate; Fimaporfin A; Tetraphenyl chlorin disulfonate. Grades: ≥95%. CAS No. 501083-97-2. Molecular formula: C44H32N4O6S2. Mole weight: 776.88. | |
| Triolein | Triolein occurs as a clear, colorless to yellowish oily liquid, and is tasteless and odorless. Synonyms: Captex GTO; glycerol trielaidate; glyceryl trioleate; 9-octadecenoic acid-1, 2, 3-propanetriyl ester; olein; 1, 2, 3-propanetriyl tris((E)-9-octadecenoate); trielaidin; trielaidoylglycerol; 1, 2, 3-tri(cis-9-ctadecenoyl) glycero. CAS No. 122-32-7. Product ID: PE-0592. Molecular formula: C57H104O6. Mole weight: 885.43. Category: Emollient; Penetration enhancer; Solubilizing Agents; Solvent. Product Keywords: Excipients for Liquid Dosage Form; Solubilizer Excipients; PE-0592; Triolein; Emollient; Penetration enhancer; Solubilizing Agents; Solvent; C57H104O6; 122-32-7. UNII: O05EC62663. Grade: Pharmceutical Excipients. Administration route: Injection. Dosage Form: liposomal suspension for epidural injections. Stability and Storage Conditions: Triolein is classified as a stable compound but is sensitive to air and light. It should be stored in tightly sealed containers in a dry area at 2-8°C. Thermal decomposition of triolein may lead to release of irritating gases and vapors such as carbon oxides. Exposure to air and moisture over prolonged periods should be avoided. Source and Preparation: Triolein is manufactured by the esterification of fractionated fatty acids, mainly oleic acid and glycerin. Applications: Triolein is used as a solubilizer and solvent in injectable preparations. It has been used in marketed preparation | |
| Vasoactive Intestinal Peptide (Human, Porcine, Rat) (H-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2) | Acts as a mitogenic factor for embryonic neurons in the sympathetic nervous system. Has powerful hypotensive and vasodilatory effects. Behaves either as a circulating hormone or as a neurotransmitter. Stimulates cAMP production in rat peritoneal macrophages. Inhibits the growth of human small-cell lung carcinoma (SCLC) both in vitro and in vivo, suggesting that it may be useful as a less toxic alternative to conventional chemotherapeutic agents in the treatment of SCLC. Nitric oxide stimulates the release of this peptide. Group: Biochemicals. Grades: Highly Purified. CAS No. 40077-57-4. Pack Sizes: 500ug, 1mg. US Biological Life Sciences. | Worldwide |
| Wax, White | White wax consists of tasteless, white or slightly yellow-colored sheets or fine granules with some translucence. Its odor is similar to that of yellow wax but is less intense. Synonyms: Bleached wax; cera alba; E901. CAS No. 8012-89-3. Product ID: PE-0603. Category: Controlled-release Agents; Stabilizing Agents; Stiffening Agents. Product Keywords: Other Materials; Stabilizers; PE-0603; Wax, White; Controlled-release Agents; Stabilizing Agents; Stiffening Agents; ; 8012-89-3. UNII: 7G1J5DA97F. Chemical Name: White beeswax. Grade: Pharmceutical Excipients. Administration route: Oral; rectal, topical, and vaginal. Dosage Form: Oral capsules and tablets; rectal, topical, and vaginal preparations. Stability and Storage Conditions: When the wax is heated above 150°C, esterification occurs with a consequent lowering of acid value and elevation of melting point. White wax is stable when stored in a well-closed container, protected from light. Source and Preparation: Yellow wax (beeswax) is obtained from the honeycomb of the bee; see Wax, Yellow. Subsequent treatment with oxidizing agents bleaches the wax to yield white wax. Applications: White wax is a chemically bleached form of yellow wax and is used in similar applications: for example, to increase the consistency of creams and ointments, and to stabilize water-in-oil emulsions. White wax is used to polish sugar-coated tablets and to adjust the melting point of suppositorie | |
| Wax, Yellow | Yellow or light brown pieces or plates with a fine-grained matt, noncrystalline fracture and a faint characteristic odor. The wax becomes soft and pliable when warmed. Synonyms: Apifil; cera flava; E901; refined wax. CAS No. 8012-89-3. Product ID: PE-0601. Category: Controlled-release Agents; Polishing Agents; Stabilizing Agents; Stiffening Agents. Product Keywords: Other Materials; Stabilizers; PE-0601; Wax, Yellow; Controlled-release Agents; Polishing Agents; Stabilizing Agents; Stiffening Agents; ; 8012-89-3. UNII: 2ZA36H0S2V. Chemical Name: Yellow beeswax. Grade: Pharmceutical Excipients. Administration route: Oral and topical. Dosage Form: Oral capsules and tablets, and topical preparations. Stability and Storage Conditions: When the wax is heated above 150°C esterification occurs with a consequent lowering of acid value and elevation of melting point. Yellow wax is stable when stored in a well-closed container, protected from light. Source and Preparation: Yellow wax is a natural secretion of bees and is obtained commercially from honeycombs. Honey is abstracted from combs either by draining or centrifugation, and water is added to the remaining wax to remove soluble impurities. Hot water is then added to form a floating melt, which is strained to remove foreign matter. The wax is then poured into flat dishes or molds to cool and harden. Applications: Yellow wax is used in food, cosmetics, and confectionery produc | |
| Xanthan Gum | Xanthan gum occurs as a cream- or white-colored, odorless, freeflowing, fine powder. Synonyms: Corn sugar gum; E415; Grindsted; Keldent; Keltrol; polysaccharide B-1459; Rhodicare S; Rhodigel; Vanzan NF; xanthani gummi; Xantural. CAS No. 11138-66-2. Product ID: PE-0521. Molecular formula: (C35H49O29)n. Mole weight: 100000. Category: Gelling Agents; Stabilizing Agents; Suspending Agents; Sustained-release Agents; Viscosity-increasing Agents. Product Keywords: Emulsifier Excipients; Stabilizers; Suspending Agents; ; PE-0521; Xanthan Gum; Gelling Agents; Stabilizing Agents; Suspending Agents; Sustained-release Agents; Viscosity-increasing Agents; (C35H49O29)n; 11138-66-2. UNII: TTV12P4NEE. Chemical Name: Xanthan gum. Grade: Pharmceutical Excipients. Administration route: Oral; rectal and topical. Dosage Form: Oral solutions, suspensions, and tablets; rectal and topical preparations. Stability and Storage Conditions: Xanthan gum is a stable material. Aqueous solutions are stable over a wide pH range (pH 3-12), although they demonstrate maximum stability at pH 4-10 and temperatures of 10-60°C. Xanthan gum solutions of less than 1% w/v concentration may be adversely affected by higher than ambient temperatures: for example, viscosity is reduced. Xanthan gum provides the same thickening, stabilizing, and suspending properties during long-term storage at elevated temperatures as it does at ambient conditions. In addition, it ens | |
| XMT-1001 | Polymeric camptothecin prodrug XMT-1001 is a polymeric prodrug of camptothecin (CPT) with potential antineoplastic activity. Polymeric camptothecin prodrug XMT-1001 consists of CPT conjugated to the 60-70 kDa, inert, bio-degradable, hydrophilic copolymer poly[1-hydroxymethylene hydroxymethyl formal] (PHF). Through a dual-phase, non-enzymatic release mechanism, CPT is first released in plasma from XMT-1001 as the lipophilic prodrugs CPT-SI (a succinimidoglycinate derivative) and CPT-SA (a succinamidoyl glycinate derivative), which are then hydrolyzed within tissues to release the lactone form of CPT. CPT inhibits the catalytic activity of DNA topoisomerase I, thereby inhibiting DNA replication and inducing apoptosis. This agent may exhibit a more favorable pharmacokinetic profile than other agents in the same class. Synonyms: XMT-1001; XMT1001; XMT 1001; A poly(1-hydroxymethylethylene hydroxymethylformal) (Fleximer)-camptothecin conjugate. CAS No. 1252797-26-4. | |
| Zinc Acetate | Zinc acetate occurs as white crystalline, lustrous plates with a faint acetic odor and an astringent taste. Synonyms: Acetic acid, zinc salt; dicarbomethoxy zinc; zinc acetas dihydricus; zinc (II) acetate; zinc diacetate; zinc ethanoate. Product ID: PE-0607. Category: Emollient; Emulsion Stabilizer; Gelling Agents; Opacifier; Stabilizing Agents. Product Keywords: Other Materials; Stabilizers; PE-0607; Zinc Acetate; Emollient; Emulsion Stabilizer; Gelling Agents; Opacifier; Stabilizing Agents;. UNII: FM5526K07A. Chemical Name: Zinc acetate dihydrate ; Zinc acetate anhydrous. Grade: Pharmceutical Excipients. Administration route: SC ; topical. Dosage Form: SC injections; topical lotions and solutions. Stability and Storage Conditions: Zinc acetate loses water of hydration above 100°C. Zinc acetate should be stored in an airtight container in a cool, dry, place. Source and Preparation: Zinc acetate is synthesized by reacting zinc oxide with glacial acetic acid, with subsequent crystallization, separation by centrifugation, and drying and milling of the crystals. No organic solvents are used during the synthesis. Applications: Zinc acetate has been used as an excipient in a variety of pharmaceutical formulations including topical gels, lotions, and solutions, and subcutaneous injections. It has also been investigated for use in an oral controlled-release formulation for water-soluble drugs in combination with sodium algina | |
| 1,5-Isoquinolinediol | 1,5-Isoquinolinediol is a PARP1 inhibitor (IC50 value 0.39 - 1.00 μM) and neuroprotective agent leading to an increase up to 8-fold in the absolute frequency of gene targeting in the correction of the mutation at the stable integrated HSV tk gene in mouse Ltk cells. 1,5-Isoquinolinediol is also an inducible nitric oxide synthase (NOS2) inhibitor. 1,5-Isoquinolinediol significantly inhibited mitochondrial membrane potential loss, AIF (apoptosis inducing factor) and cytochrome c release from the mitochondria. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: 1,5-Dihydroxyisoquinoline; Isoquinoline-1,5-diol; 5-Hydroxy-1(2H)-isoquinolinone; 5-Hydroxyisocarbostyril. Grades: 99%. CAS No. 5154-2-9. Molecular formula: C9H7NO2. Mole weight: 161.16. | |
| 1-Cyclopentylpropan-2-one | 1-Cyclopentylpropan-2-one is a reagent that is used in the synthesis of Cyclopentamine which is a vasoconstrictor that acts as a releasing agent of the neurotransmitters norepinephrine, epinephrine and dopamine. Group: Biochemicals. Grades: Highly Purified. CAS No. 1122-98-1. Pack Sizes: 10mg, 50mg. Molecular Formula: C8H14O, Molecular Weight: 126.2. US Biological Life Sciences. | Worldwide |
| 1-Dodecylimidazole | 1-Dodecylimidazole (N-Dodecylimidazole) is a lysosomotropic detergent and a cytotoxic agent. 1-Dodecylimidazole causes cell death by its acid-dependent accumulation in lysosomes, disruption of the lysosomal membrane, and releaseof cysteine proteases into the cytoplasm. 1-Dodecylimidazole has hypocholesterolaemic activity and broad-spectrum antifungal activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-DODECYLIMIDAZOLE;1-DODECYL-1H-IMIDAZOLE;1-dodecyl-1h-imidazol;1-dodecyl-imidazol;1-laurylimidazole;n-laurylimidazole;N-DODECYLIMIDAZOLE;1-Dodecylimidazole,95%. Product Category: Inhibitors. Appearance: Clourless Liquid. CAS No. 4303-67-7. Molecular formula: C15H28N2. Mole weight: 236.4. Purity: 0.98. IUPACName: 1-dodecylimidazole. Canonical SMILES: CCCCCCCCCCCCN1C=CN=C1. ECNumber: 224-314-4. Product ID: ACM4303677. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 2,3-Dihydro-5-methoxy-6-methyl-1H-inden-2-amine Hydrochloride | 2,3-Dihydro-5-methoxy-6-methyl-1H-inden-2-amine is an highly selective serotonin releasing agent and produces entactogen effects. Group: Biochemicals. Grades: Highly Purified. CAS No. 132980-17-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C11H16ClNO, Molecular Weight: 213.7. US Biological Life Sciences. | Worldwide |
| 2,3-Dimethyl-6-tert-butyldimethylsilyl-b-cyclodextrin | 2,3-Dimethyl-6-tert-butyldimethylsilyl-b-cyclodextrin, a compound widely employed in the biomedical field, plays a pivotal role in enhancing drug efficacy through its distinct structural properties. This versatile agent facilitates the solubilization and regulated release of drugs afflicted with poor solubility or instability. Its profound implications extend to formulating treatments for ailments including but not limited to cancer, cardiovascular disorders, and neurodegenerative maladies. Synonyms: 2, 3-Di-O-methyl-6-O-tert-butyldimethylsilyl) cyclomaltoheptaose Heptakis(2,3-di-O-methyl-6-O-tert-butyldimethylsilyl)-b-cyclodextrin. CAS No. 123155-04-4. Molecular formula: C98H196O35Si7. Mole weight: 2131.18. | |
| 2-Hydroxy-3-phenoxypropyl acrylate | 2-Hydroxy-3-phenoxypropyl acrylate. Uses: Polymeric membranes for controlled drug release systems may be prepared by the photosynthesis of 2-hydroxy-3-phenoxypropyl acrylate by uv radiation. tthe product can be used as a curing agent during the fabrication of poly (phenylene ether)-based substrate materials. Group: Monomers. Alternative Names: (2-Hydroxy-3-phenoxypropyl) prop-2-enoate, 3-Phenoxy-2-hydroxypropyl acrylate. CAS No. 16969-10-1. Pack Sizes: Packaging 100 mL in poly bottle. Product ID: (2-hydroxy-3-phenoxypropyl) prop-2-enoate. Molecular formula: 222.24. Mole weight: H2C=CHCO2CH2CH(OH)CH2OC6H5. OC(COC(=O)C=C)COc1ccccc1. 1S/C12H14O4/c1-2-12 (14)16-9-10 (13)8-15-11-6-4-3-5-7-11/h2-7, 10, 13H, 1, 8-9H2. HHQAGBQXOWLTLL-UHFFFAOYSA-N. | |
| 2-Methyl-3-[(2S)-2-pyrrolidinylmethoxy]-pyridine Dihydrochloride | 2-Methyl-3-[(2S)-2-pyrrolidinylmethoxy]-pyridine Dihydrochloride is a selective neuronal nicotinic receptor (NNR) modulator and a neuroprotective agent that has therapeutic potential for treating cognitive disorders. 2-Methyl-3-[(2S)-2-pyrrolidinylmethoxy]-pyridine Dihydrochloride is selective for the neuronal nicotinic acetylcholine receptors (nAChRs) subtype, which modulate the release of neurotransmitters (acetylcholine and dopamine). Group: Biochemicals. Grades: Highly Purified. CAS No. 161416-61-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C11H16N2O 2HCl, Molecular Weight: 192.267292. US Biological Life Sciences. | Worldwide |
| 3-Hydroxy 4-Methoxyphenethylamine HCl | An impurity of Tyramine. Tyramine is a catecholamine releasing agent that binds to both TAAR1 and TAAR2 as an agonist. Tyramine is derived from Tyrosine. Molecular formula: C9H13NO2.HCl. Mole weight: 203.67. | |
| 3-Methoxytyramine Glucuronide | An impurity of Tyramine. Tyramine is a catecholamine releasing agent that binds to both TAAR1 and TAAR2 as an agonist. Tyramine is derived from Tyrosine. Molecular formula: C15H21NO8. Mole weight: 343.34. | |
| 3-Methoxytyramine Sulfate | An impurity of Tyramine. Tyramine is a catecholamine releasing agent that binds to both TAAR1 and TAAR2 as an agonist. Tyramine is derived from Tyrosine. Synonyms: [4-(2-aminoethyl)-2-methoxyphenyl] hydrogen sulfate; 3-Methyldopamine O-sulfate; CHEBI:133708; 4-(2-aminoethyl)-2-methoxyphenyl hydrogen sulfate. Molecular formula: C9H13NO5S. Mole weight: 247.27. | |
| 4-HO-DET | 4-HO-DET is a derivative of Tryptamine, which is a non-selective serotonin receptor agonist and serotonin-norepinephrine-dopamine releasing agent (SNDRA). Synonyms: 4-Hydroxy-N,N-diethyltryptamine; 3-(2-Diethylaminoethyl)indol-4-ol; 1H-Indol-4-ol, 3-[2-(diethylamino)ethyl]-; 4-hydroxy DET. Grades: 95%. CAS No. 22204-89-3. Molecular formula: C14H20N2O. Mole weight: 232.32. | |
| 4-methoxyphenyl 3-O-(2-Naphthylmethyl)-4,6-O-Benzylidene-1-α-D-Mannopyranoside | 4-Methoxyphenyl 3-O-(2-Naphthylmethyl)-4,6-O-Benzylidene-1-α-D-Mannopyranoside, an innovative drug candidate, exhibits promise for countering viral ailments, influenza included. Its mechanism entails controlling the viral neuraminidase enzyme - an agent vital to releasing progeny viruses from infected cells. | |
| (+)-[6]-Gingerol | (+)-[6]-Gingerol is a bioactive compound found in ginger (Zingiber officinale) with antioxidant activity, which functions as an anti-inflammatory and antitumor agent. (+)-[6]-Gingerol down regulates proinflammatory cytokine release by macrophages. (+)-[6]-Gingerol has been shown to inhibit COX-2 expression by blocking the activation of p38 MAP kinase and NF-κB in phorbol ester-stimulated mouse skin. Group: Biochemicals. Alternative Names: (5S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone; (S)-(+)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone; (+)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone; (5S)-[6]-Gingerol; (S)-(+)-[6]Gingerol; (S)-[6]Gingerol; [6]-Gingerol. Grades: Highly Purified. CAS No. 23513-14-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Abarelix | Abarelix is a synthetic decapeptide and antagonist of naturally occurring gonadotropin-releasing hormone (GnRH). Abarelix directly and competitively binds to and blocks the gonadotropin releasing hormone receptor in the anterior pituitary gland, thereby inhibiting the secretion and release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). In males, the inhibition of LH secretion prevents the release of testosterone. As a result, this may relieve symptoms associated with prostate hypertrophy or prostate cancer, since testosterone is required to sustain prostate growth. Check for active clinical trials or closed clinical trials using this agent. Synonyms: Plenaxis, PPI-149; PPI 149; PPI149; R-3827; R 3827; R3827. Grades: 98%. CAS No. 183552-38-7. Molecular formula: C72H95ClN14O14. Mole weight: 1416.09. | |
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