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| Product | Description | |
|---|---|---|
| 2-haloacid dehalogenase (configuration-retaining) | Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the corresponding (S)- and (R)-hydroxyalkanoic acids, respectively, with retention of configuration at C-2. [See also EC 3.8.1.2 (S)-2-haloacid dehalogenase, EC 3.8.1.9 (R)-2-haloacid dehalogenase and EC 3.8.1.10 2-haloacid dehalogenase (configuration-inverting)]. Group: Enzymes. Synonyms: 2-haloalkanoic acid dehalogenase; 2-haloalkanoid acid halidohydrolase; DL-2-haloacid dehalogenase; DL-DEXr. Enzyme Commission Number: EC 3.8.1.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4741; 2-haloacid dehalogenase (configuration-retaining); EC 3.8.1.11; 2-haloalkanoic acid dehalogenase; 2-haloalkanoid acid halidohydrolase; DL-2-haloacid dehalogenase; DL-DEXr. Cat No: EXWM-4741. |  |
| α,α-trehalose phosphorylase (configuration-retaining) | Unlike EC 2.4.1.64, α,α-trehalose phosphorylase, this enzyme retains its anomeric configuration. Vanadate is a strong competitive inhibitor of this reversible reaction. Group: Enzymes. Synonyms: trehalose phosphorylase[ambiguous]. Enzyme Commission Number: EC 2.4.1.231. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2461; α,α-trehalose phosphorylase (configuration-retaining); EC 2.4.1.231; trehalose phosphorylase[ambiguous]. Cat No: EXWM-2461. | |
| UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining) | Contains NAD+ as a cofactor. This is the first enzyme in the biosynthetic pathway of N,N'-diacetylbacillosamine, the first carbohydrate in the glycoprotein N-linked heptasaccharide in Campylobacter jejuni. This enzyme belongs to the short-chain dehydrogenase/reductase family of enzymes. Group: Enzymes. Synonyms: PglF. Enzyme Commission Number: EC 4.2.1.135. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4976; UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining); EC 4.2.1.135; PglF. Cat No: EXWM-4976. | |
| 1,2-diacylglycerol 3-α-glucosyltransferase | The enzyme from the bacterium Acholeplasma laidlawii, which lacks a cell wall, produces the major non-bilayer lipid in the organism. The enzyme from the bacterium Agrobacterium tumefaciens acts under phosphate deprivation, generating glycolipids as surrogates for phospholipids. The enzyme belongs to the GT4 family of configuration-retaining glycosyltransferases. Many diacylglycerols with long-chain acyl groups can act as acceptors. cf. EC 2.4.1.336, monoglucosyldiacylglycerol synthase. | |
| 1,2-diacylglycerol 3-α-glucosyltransferase | The enzyme from the bacterium Acholeplasma laidlawii, which lacks a cell wall, produces the major non-bilayer lipid in the organism. The enzyme from the bacterium Agrobacterium tumefaciens acts under phosphate deprivation, generating glycolipids as surrogates for phospholipids. The enzyme belongs to the GT4 family of configuration-retaining glycosyltransferases. Many diacylglycerols with long-chain acyl groups can act as acceptors. cf. EC 2.4.1.336, monoglucosyldiacylglycerol synthase. Group: Enzymes. Synonyms: mgs (gene name); UDP-glucose:diacylglycerol glucosyltransferase; UDP-glucose:1,2-diacylglycerol glucosyltransferase; uridine diphosphoglucose-diacylglycerol glucosyltransferas. Enzyme Commission Number: EC 2.4.1.337. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2575; 1,2-diacylglycerol 3-α-glucosyltransferase; EC 2.4.1.337; mgs (gene name); UDP-glucose:diacylglycerol glucosyltransferase; UDP-glucose:1,2-diacylglycerol glucosyltransferase; uridine diphosphoglucose-diacylglycerol glucosyltransferase; UDP-glucose-diacylglycerol glucosyltransferase; UDP-glucose:1,2-diacylglycerol 3-D-glucosyltransferase; UDP-glucose:1,2-diacyl-sn-glycerol 3-D-glucosyltransferase; 1,2-diacylglycerol 3-glucosyltransferase (ambiguous). Cat No: EXWM-2575. | |
| (±)-18-Methoxycoronaridine | 18-Methoxycoronaridine is a derivative of ibogaine. It is a α3β4 nicotinic antagonist and, in contrast to ibogaine, has no affinity at the α4β2 subtype nor at NMDA-channels nor at the serotonin transporter, and has significantly reduced affinity for sodium channels and for the σ receptor, but retains modest affinity for μ-opioid receptors where it acts as an antagonist of κ-opioid receptors. Synonyms: 18-Methoxycoronaridine; (+/-)-18-Methoxycoronaridine. CAS No. 188125-42-0. Molecular formula: C22H28N2O3. Mole weight: 368.5. |  |
| 18-Methoxycoronaridine | 18-Methoxycoronaridine is a derivative of ibogaine. It is a α3β4 nicotinic antagonist and, in contrast to ibogaine, has no affinity at the α4β2 subtype nor at NMDA-channels nor at the serotonin transporter, and has significantly reduced affinity for sodium channels and for the σ receptor, but retains modest affinity for μ-opioid receptors where it acts as an antagonist, and κ-opioid receptors. Synonyms: (-)-18-methoxycoronaridine. Grade: > 95%. CAS No. 308123-60-6. Molecular formula: C22H28N2O3. Mole weight: 368.47. | |
| 23S rRNA (adenine2503-C8)-methyltransferase | This enzyme is a member of the 'AdoMet radical' (radical SAM) family. S-Adenosyl-L-methionine acts as both a radical generator and as the source of the appended methyl group. It contains an [4Fe-S] cluster. Cfr is an plasmid-acquired methyltransferase that protects cells from the action of antibiotics. The enzyme methylates adenosine at position 2503 of 23S rRNA by a radical mechanism, transferring a CH2 group from S-adenosyl-L-methionine while retaining the hydrogen at the C-8 position of the adenine. Cfr first transfers an CH2 group to a conserved cysteine (Cys338 in Staphylococcus aureus), the generated radical from a second S-adenosyl-L-methionine then attacks the methyl group, exctracting a hydrogen. The formed radical forms a covalent intermediate with the adenine group of the tRNA. The enzyme will also methylate 2-methyladenine produced by the action of EC 2.1.1.192 [23S rRNA (adenine2503-C2)-methyltransferase]. Group: Enzymes. Synonyms: Cfr (gene name). Enzyme Commission Number: EC 2.1.1.224. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1827; 23S rRNA (adenine2503-C8)-methyltransferase; EC 2.1.1.224; Cfr (gene name). Cat No: EXWM-1827. | |
| 2-haloacid dehalogenase (configuration-inverting) | Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the corresponding (R)- and (S)-hydroxyalkanoic acids, respectively, with inversion of configuration at C-2. The enzyme from Pseudomonas sp. 113 acts on 2-haloalkanoic acids whose carbon chain lengths are five or less. [See also EC 3.8.1.2 (S)-2-haloacid dehalogenase, EC 3.8.1.9 (R)-2-haloacid dehalogenase and EC 3.8.1.11 2-haloacid dehalogenase (configuration-retaining)]. Group: Enzymes. Synonyms: 2-haloalkanoic acid dehalogenase; 2-haloalkanoid acid halidohydrolase; DL-2-haloacid dehalogenase; DL-2-haloacid dehalogenase (inversion of configuration); DL-2-haloacid halidohydrolase (inversion of configuration); DL-DEXi; (R,S)-2-haloacid dehalogenase (configuration-inverting). Enzyme Commission Number: EC 3.8.1.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4740; 2-haloacid dehalogenase (configuration-inverting); EC 3.8.1.10; 2-haloalkanoic acid dehalogenase; 2-haloalkanoid acid halidohydrolase; DL-2-haloacid dehalogenase; DL-2-haloacid dehalogenase (inversion of configuration); DL-2-haloacid halidohydrolase (inversion of configuration); DL-DEXi; (R,S)-2-haloacid dehalogenase (configuration-inverting). Cat No: EXWM-4740. | |
| 2-hydroxyethylphosphonate dioxygenase | Requires non-heme-Fe(II). Isolated from some bacteria including Streptomyces hygroscopicus and Streptomyces viridochromogenes. The pro-R hydrogen at C-2 of the ethyl group is retained by the formate ion. Any stereochemistry at C-1 of the ethyl group is lost. One atom from dioxygen is present in each product. Involved in phosphinothricin biosynthesis. Group: Enzymes. Synonyms: HEPD; phpD (gene name); 2-hydroxyethylphosphonate:O2 1,2-oxidoreductase (hydroxymethylphosphonate forming). Enzyme Commission Number: EC 1.13.11.72. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0592; 2-hydroxyethylphosphonate dioxygenase; EC 1.13.11.72; HEPD; phpD (gene name); 2-hydroxyethylphosphonate:O2 1,2-oxidoreductase (hydroxymethylphosphonate forming). Cat No: EXWM-0592. | |
| 3-dehydroquinate synthase | Requires Co2+ and bound NAD+. The hydrogen atoms on C-7 of the substrate are retained on C-2 of the product. Group: Enzymes. Synonyms: 5-dehydroquinate synthase; 5-dehydroquinic acid synthetase; dehydroquinate synthase; 3-dehydroquinate synthetase; 3-deoxy-arabino-heptulosonate-7-phosphate phosphate-lyase (cyclizing); 3-deoxy-arabino-heptulonate-7-phosphate phosphate-lyase (cyclizing); 3-deoxy-arabino-heptulonate-7-phosphate phosphate-lyase (cyclizing; 3-dehydroquinate-forming). Enzyme Commission Number: EC 4.2.3.4. CAS No. 37211-77-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5198; 3-dehydroquinate synthase; EC 4.2.3.4; 37211-77-1; 5-dehydroquinate synthase; 5-dehydroquinic acid synthetase; dehydroquinate synthase; 3-dehydroquinate synthetase; 3-deoxy-arabino-heptulosonate-7-phosphate phosphate-lyase (cyclizing); 3-deoxy-arabino-heptulonate-7-phosphate phosphate-lyase (cyclizing); 3-deoxy-arabino-heptulonate-7-phosphate phosphate-lyase (cyclizing; 3-dehydroquinate-forming). Cat No: EXWM-5198. | |
| 5(6)-CFDA | 5(6)-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 5-(6)-Carboxyfluorescein diacetate; CFDA. CAS No. 124387-19-5. Pack Sizes: 50 mg; 100 mg. Product ID: HY-D0722. |  |
| 5-CFDA | 5-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 5-Carboxyfluorescein diacetate. CAS No. 79955-27-4. Pack Sizes: 50 mg. Product ID: HY-D0047. | |
| 5-Iminodaunorubicin | 5-Iminodaunorubicin is a quinone-modified anthracycline that retains antitumor activity [1]. 5-Iminodaunorubicin produces protein-concealed DNA strand breaks in cancer cells [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 72983-78-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-138645. | |
| 5-Iminodaunorubicin hydrochloride | 5-Iminodaunorubicin hydrochloride is a quinone-modified anthracycline that retains antitumor activity [1]. 5-Iminodaunorubicin hydrochloride produces protein-concealed DNA strand breaks in cancer cells [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67324-99-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-138645A. | |
| 6-CFDA | 6-CFDA is a common aliphatic luciferin-line organism. CFDA conducts free diffusion into cells, and then it is hydrolyzed into carboxyl fluorescein (CF) by intracellular non-specific lipase. CF containing portion contains an additional negative charge so that it is better retained in cells, compared to fluorescein dyes [1] [2] [3] [4]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: 6-Carboxyfluorescein diacetate. CAS No. 3348-3-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-D0721. | |
| (9E)-Erythromycin A oxime | (9E)-Erythromycin A oxime is a derivative of erythromycin A, where the ketone group at the C9 position of the lactone ring is converted to an oxime group (-C=NOH) in the (E)-configuration. This structural modification can enhance the compound's chemical stability and resistance to acid degradation, which is beneficial for oral bioavailability. Like erythromycin, this oxime derivative retains the ability to inhibit bacterial protein synthesis by binding to the 50S ribosomal subunit, exhibiting bacteriostatic activity. It may be investigated for improved pharmacokinetic properties or as an intermediate in the synthesis of macrolide derivatives for combating bacterial resistance. Synonyms: Erythromycin A oxime; (E)-Erythromycin A oxime; (E)-Erythromycin oxime; Erythromycin, 9-oxime, (9E)-; (9E)-Erythromycin, 9-oxime; (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(hydroxyimino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one. Grade: ≥95%. CAS No. 111321-02-9. Molecular formula: C37H68N2O13. Mole weight: 748.95. | |
| α-D-xyloside xylohydrolase | The enzyme catalyses hydrolysis of a terminal, unsubstituted xyloside at the extreme reducing end of a xylogluco-oligosaccharide. Representative α-xylosidases from glycoside hydrolase family 31 utilize a two-step (double-displacement) mechanism involving a covalent glycosyl-enzyme intermediate, and retain the anomeric configuration of the product. Group: Enzymes. Synonyms: α-xylosidase. Enzyme Commission Number: EC 3.2.1.177. α-Xylosidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3860; α-D-xyloside xylohydrolase; EC 3.2.1.177; α-xylosidase. Cat No: EXWM-3860. | |
| Aluminum-doped zinc oxide ink for inkjet printing | H-DZ01015 semi conductive ink developed for the printed electronics is particularly well suited for OPV and PV. This ink shows great performance on Drop On Demand (DOD) inkjet printers. The use of H-DZ01015 semiconductive ink is greatly improving the devices performances by reducing the roughness of the TCE without a negative impact on the electrical conductivity and the transparency. Life time of the devices is also increased. The use of H-DZ01015 provides ETL layer with high performances. In addition, compared to standard ETL, the PCE not retained even with higher thickness. Group: 3d printing materials organic solar cell (opv) materials printed electronic materials. Alternative Names: AZO dispersion,AZO ink,Al-doped ZnO ink. Mole weight: ZnO. |  |
| Aluminum-doped zinc oxide ink for spin coating/slot-die coating | Helios'Ink H-DZ41006 semiconductive ink developed for the printed electronics is particularly well suited for OPV and PV.This ink shows great performance on spin coating and slot die coating and is compatible with various flexible substrates. Life time of the devices is also increased.The use of Helios'Ink H-DZ41006 provides ETL layer with high performances. In addition, compared to standard ETL, the PCE not retained even with higher thickness. Group: 3d printing materials organic solar cell (opv) materials printed electronic materials. Alternative Names: AZO dispersion, AZO ink, Al-doped ZnO ink. Mole weight: ZnO. | |
| Aminoethoxyvinyl glycine Hydrochloride (ABG 3168) | Ethylene, an important plant regulator, is synthesized from S-adenosyl-L-methionine by the sequential action of 1-amino-cyclopropane-carboxylate (ACC) synthases (ACSs) and ACC oxidases (ACOs). Aminoethoxyvinyl glycine is an inhibitor of ethylene biosynthesis that, at 1uM, blocks the activity of both ACSs and ACOs.1 Through this action, it reduces ethylene-mediated changes in plant growth and development.2,3,4 Aminoethoxyvinyl glycine also inhibits cystathionine γ-lyase (Ki = 10.5uM) with slow- and tight-binding characteristics.5. Group: Biochemicals. Alternative Names: (2S,3E)-2-Amino-4-(2-aminoethoxy)-3-butenoic Acid Monohydrochloride; [S-(E)]-2-Amino-4-(2-aminoethoxy)-3-butenoic Acid Monohydrochloride; (S)-trans-2-Amino-4-(2-aminoethoxy)-3-butenoic Acid Hydrochloride; ABG 3168 Hydrochloride; L-2-Amino-4-(2'-aminoethoxy)-trans-3-butenoic Acid Hydrochloride; ReTain Hydrochloride; ReTain (plant growth regulator) Hydrochloride. Grades: Highly Purified. CAS No. 55720-26-8. Pack Sizes: 1mg, 5mg, 10mg. Molecular Formula: C?H??ClN?O?, Molecular Weight: 196.63. US Biological Life Sciences. |  Worldwide |
| (Ara-f)3-Hyp β-L-arabinobiosidase | The enzyme, which was identified in the bacterium Bifidobacterium longum JCM1217, is specific for (Ara-f)3-Hyp, a sugar chain found in hydroxyproline-rich glyoproteins such as extensin and lectin. The enzyme was not able to accept (Ara-f)2-Hyp or (Ara-f)4-Hyp as substrates. In the presence of 1-alkanols, the enzyme demonstrates transglycosylation activity, retaining the anomeric configuration of the arabinofuranose residue. Group: Enzymes. Synonyms: hypBA2 (gene name); β-L-arabinobiosidase. Enzyme Commission Number: EC 3.2.1.187. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3871; (Ara-f)3-Hyp β-L-arabinobiosidase; EC 3.2.1.187; hypBA2 (gene name); β-L-arabinobiosidase. Cat No: EXWM-3871. | |
| ARCC-4 | ARCC-4 is a PROTAC, acting as an androgen receptor degrader. ARCC-4 is a low-nanomolar androgen receptor degrader able to degrade about 95% of cellular androgen receptors. It inhibits prostate tumor cell proliferation, degrades clinically relevant androgen receptor point mutants and unlike enzalutamide, retains antiproliferative effect in a high androgen environment. Synonyms: ARCC-4; 1973403-00-7; (2S,4R)-1-((S)-2-(2-(4-((4'-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-[1,1'-biphenyl]-4-yl)oxy)butoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide; CHEMBL4540528; SCHEMBL17946930; DUPAJELXESPTNF-PPZGWQTASA-N; AKOS040741162; MS-31874; HY-130492; CS-0108331; EN300-7526556; Z3482428589; O1-(ABM-14 ether), O4-(Methylcarboxamide with AHPC) Butanediol; (2S,4R)-1-[(2S)-2-(2-{4-[(4'-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-sulfanylideneimidazolidin-1-yl}-[1,1'-biphenyl]-4-yl)oxy]butoxy}acetamido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide. Grade: 99%. CAS No. 1973403-00-7. Molecular formula: C53H56F3N7O7S2. Mole weight: 1024.18. | |
| avermitilol synthase | Requires Mg2+. The recombinent enzyme gives avermitilol (85%) plus traces of germacrene A, germacrene B and viridiflorol. The (1S)-hydrogen of farnesyl diphosphate is retained. Group: Enzymes. Enzyme Commission Number: EC 4.2.3.96. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5260; avermitilol synthase; EC 4.2.3.96. Cat No: EXWM-5260. | |
| β-Amyloid 31-35 | β-Amyloid 31-35 is a fragment of Amyloid-β peptide found in plaques associated with Alzheimer's disease. It is also the shortest sequence of native Amyloid-β peptide that retains neurotoxic activity. Synonyms: beta-Amyloid (31-35); Amyloid b-Protein (31-35); H-ILE-ILE-GLY-LEU-MET-OH; Isoleucinyl-isoleucinyl-glycinyl-leucinyl-methionine. Grade: >95%. CAS No. 149385-65-9. Molecular formula: C25H47N5O6S. Mole weight: 545.74. | |
| β-Endorphin (6-31) (human) | β-Endorphin (6-31) (human) is a fragment of β-endorphin that retains the C-terminal. It acts as a non-opioid β-endorphin antagonist, and mediates effects on the immune system. Synonyms: H-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu-OH; L-threonyl-L-seryl-L-alpha-glutamyl-L-lysyl-L-seryl-L-glutaminyl-L-threonyl-L-prolyl-L-leucyl-L-valyl-L-threonyl-L-leucyl-L-phenylalanyl-L-lysyl-L-asparagyl-L-alanyl-L-isoleucyl-L-isoleucyl-L-lysyl-L-asparagyl-L-alanyl-L-tyrosyl-L-lysyl-L-lysyl-glycyl-L-glutamic acid; b-Endorphin (6-31). Grade: ≥90%. CAS No. 77761-27-4. Molecular formula: C131H218N34O40. Mole weight: 2909.38. | |
| Beta-lactamase substrates, CCF4-AM | CCF4-AM is a lipophilic esterified form of CCF4 substrate that can easily enter cells. CCF4-AM can be cleavaged by endogenous cytoplasmic esterase and rapidly converted into negatively charged CCF4 retained in the cytosol. CCF4, a fluorescence resonance energy transfer (FRET) substrate consisting of a cephalosporin core linking 7-hydroxy-coumarin to Frescein, can be used as a sensitive reporter of mammalian β-lactamase gene expression. | |
| Bird's nest peptide | Bird's nest peptide is a small molecule peptide made from bird's nest by enzymolysis. The product retains sialic acid, minerals and other nutrients contained in bird's nest. Product ID: CDF4-0246. Category: Protein peptide. Product Keywords: Protein Peptides; Bird's nest peptide; CDF4-0246; Protein peptide;. Applications: It is widely used in food, cosmetics and medicine. Product Description: The use of bird's nest peptide is convenient, which expands the new application direction of bird's nest. |  |
| Bodipy Cyclopamine | A fluorescent Cyclopamine derivative that retains potency in Shh signaling inhibition (IC??=150nm). Group: Biochemicals. Alternative Names: [5-[(3, 5-Dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-N-[6-[[2-[(3S, 3'R, 3'aS, 6'S, 6aS, 6bS, 7'aR, 2'R, 11aS, 11bR)-1, 2, 3, 3', 3'a, 4, 5', 6, 6', 6a, 6b, 7, 7', 7'a, 8, 11, 11a, 11b-octadecahydro-3-hydroxy-3', 6', 10, 11b-tetramethylspiro[9H-benzo[a]fluorene-9, 2'(4'H)-furo[3, 2-b]pyridin]-4'-yl]ethyl]amino]-6-oxohexyl]-1H-pyrrole-2-propanamidato-κN1]difluoro-boron. Grades: Highly Purified. CAS No. 334658-24-1. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| Bovine collagen peptide | Bovine collagen peptide was prepared from bovine bone or skin by enzymatic hydrolysis. Use advanced technology to remove inorganic salt, fat and non-collagen protein, retain collagen essence, and can customize products according to customer needs. Product ID: CDF4-0244. Category: Protein peptide. Product Keywords: Protein Peptides; Bovine collagen peptide; CDF4-0244; Protein peptide;. Applications: It is widely used in food, cosmetics and medicine. Product Description: Bovine collagen peptide has small molecular weight, high purity, protein content ≥ 90%, good solubility, high thermal and acid stability. | |
| Cactus extract | Cactus extract. Applications: Cactus extract can be used in functional food, drinks, health care products and pharmaceuticals. Group: Others. Purity: 0.41736111. Appearance: Brown powder. Source: A cactus is a member of the plant family Cactaceae within the order Caryophyllales.Most species of cacti have lost true leaves, retaining only spines, which are highly modified leaves. As well as defending against herbivores, spines help prevent water loss by reducing air flow close to the cactus and providing some shade. In the absence of leaves, enlarged stems carry out photosynthesis. Cactus extract. Cat No: EXTC-176. | |
| CCG-63802 | CCG-63802 is a reversible inhibitor of regulator of G-protein signaling (RGS) protein. It is selective amongst RGS proteins, with greatest potency at RGS4. It also inhibits GTPase accelerating protein activity of RGS4, blocks its interaction with Gαo, and retains activity under reducing conditions. Synonyms: CCG-4986; CCG 4986; CCG4986. Grade: >98%. CAS No. 620112-78-9. Molecular formula: C26H18N4O2S. Mole weight: 450.51. | |
| CHAPS | CHAPS, a derivative of Cholic acid, is a zwitterionic detergent for solubilizing membrane proteins. CHAPS is used for stabilization of various protein-DNA complexes and can retain biochemical activity of proteins in solution [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 75621-03-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15435. | |
| CHAPS hydrate | CHAPS hydrate, a derivative of Cholic acid, is a zwitterionic detergent for solubilizing membrane proteins. CHAPS hydrate is used for stabilization of various protein-DNA complexes and can retain biochemical activity of proteins in solution [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 331717-45-4. Pack Sizes: 500 mg; 1 g. Product ID: HY-15435A. | |
| Chemerin-9 149-157 | Chemerin-9 (149-157), the 149-157 amino acid fragment of Chemerin-9, corresponding to the C-terminal of processed Chemerin, retains most of the activity of the full-size protein, with regard to agonism toward the chemerin R. Synonyms: Tyr-Phe-Pro-Gly-Gln-Phe-Ala-Phe-Ser; chemerin 9; L-tyrosyl-L-phenylalanyl-L-prolyl-glycyl-L-glutaminyl-L-phenylalanyl-L-alanyl-L-phenylalanyl-L-serine. Grade: ≥95%. CAS No. 676367-27-4. Molecular formula: C54H66N10O13. Mole weight: 1063.16. | |
| Chemerin-9 (149-157) acetate | Chemerin-9 (149-157) acetate, the 149-157 amino acid fragment of Chemerin-9, corresponding to the C-terminal of processed Chemerin, retains most of the activity of the full-size protein, with regard to agonism toward the chemerin R. It is the natural ligand of ChemR23 (chemerinR23). Synonyms: Chemerin-9 (human) (acetate); L-Tyrosyl-L-phenylalanyl-L-prolylglycyl-L-glutaminyl-L-phenylalanyl-L-alanyl-L-phenylalanyl-L-serine acetate; Human chemerin-9 acetate; H-Tyr-Phe-Pro-Gly-Gln-Phe-Ala-Phe-Ser-OH.CH3CO2H. Grade: ≥95%. Molecular formula: C56H70N10O15. Mole weight: 1123.23. | |
| Cholesterol Esterase, PEG Modified | PEG (Polyethylene glycol) modified cholesterol esterase (PEG Cholesterol Esterase) isone of our premier cholesterol esterase conjugates. Cholesterol esterase is an enzyme that catalyzes the hydrolysis of cholesterol esters into their sterol components and fatty acids. Cholesterol esterase has clinical applications in the determination of serum cholesterol combined with other enzymes. PEG modified cholesterol esterase shows better stability with good reactivity. All our labeled cholesterol esterase products were performed under mild reaction conditions to retain their maximum bioactivity. These conjugates were further purified by chromatography to ensure adequate applications both in-vitro and in-vivo. Conjugate ration: 20~50 peg5000/monomer. solubility: soluble in aqueous buffer. Group: Enzymes. Synonyms: PEG Cholesterol Esterase; Cholesterol Esterase-polyethylene glycol; CE-polyethylene glycol; CE-PEG; PEG-CE; PEG-Cholesterol Esterase. Cholesterol Esterase. Mole weight: ~65 kD for monomer; 400 kD for hexamer. Activity: >300 units/g. Storage: Store at -20°C. Form: Lyophilized powder. Source: Porcine pancreas. Species: Porcine. PEG Cholesterol Esterase; Cholesterol Esterase-polyethylene glycol; CE-polyethylene glycol; CE-PEG; PEG-CE; PEG-Cholesterol Esterase; Cholesterol Esterase, PEG Modified. Cat No: NATE-1587. | |
| Cholesterol Oxidase, PEG Modified | PEG (Polyethylene glycol) modified cholesterol oxidase (Cholesterol oxidase PEG) is one of our premier cholesterol oxidase conjugates. Cholesterol oxidase is an enzyme that catalyzes the oxidation of cholesterol by oxygen into cholest-4-en-3-one and H2O2. This enzyme belongs to the family of oxidoreductases. Cholesterol oxidase has been used widely in the determination of serum cholesterol combined with other enzymes. PEG modified cholesterol oxidase provides better stability of this enzyme without major compromising its bioactivity. All our labeled cholesterol oxidase products were performed under mild reaction conditions to retain their maximum bioactivity. These conjugates were further purified by chromatography to ensure adequate applications both in-vitro and in-vivo. Conjugate ration: 20~50 peg5000r. solubility: soluble in aqueous buffer. Group: Enzymes. Synonyms: PEG Cholesterol Oxidase; Cholesterol Oxidase-polyethylene glycol; CHOD-polyethylene glycol; CHOD-PEG; PEG-CHOD; PEG-Cholesterol Oxidase. CHOD. Mole weight: ~61.8 kD. Activity: >10 units/mg solid. Storage: Store at -20°C. Form: Lyophilized powder. Source: Microorganism. PEG Cholesterol Oxidase; Cholesterol Oxidase-polyethylene glycol; CHOD-polyethylene glycol; CHOD-PEG; PEG-CHOD; PEG-Cholesterol Oxidase; Cholesterol Oxidase, PEG Modified. Cat No: NATE-1588. | |
| CNX-500 | CNX-500 is a probe consisting of a covalent Btk inhibitor (CC-292) chemically linked to biotin. CNX-500 retains inhibitory activity against Btk ( IC 50 of 0.5 nM) and the ability to form a covalent bond with Btk. CNX-500 has low inhibitory effects on kinase epidermal growth factor receptor, and upstream Src-family kinases including Syk and Lyn [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1202758-21-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-100338. | |
| Daunomycinone | Daunomycinone is the aglycone core structure of the anthracycline antibiotics daunorubicin and doxorubicin, lacking their sugar moiety. As a key pharmacophore, it contributes to the DNA-intercalating and topoisomerase II inhibition properties of these drugs, enabling anticancer activity. While less potent than the glycosylated forms, daunomycinone retains cytotoxic effects by generating reactive oxygen species (ROS) and disrupting DNA replication. Synonyms: Daunorubicin Impurity A; (8S,10S)-8-Acetyl-6,8,10,11-tetrahydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione; Daunorubicin EP Impurity A; (+)-Daunomycinone; NSC 109531; (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione; Daunomycin Aglicone; Daunomycinon; Daunorubicin Aglycone; Leukaemomycinone C; Daunorubicinone; 5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-, (8S,10S)-; Epirubicin EP Impurity B. Grade: ≥95%. CAS No. 21794-55-8. Molecular formula: C21H18O8. Mole weight: 398.37. | |
| Dextrin palmitate | Dextrin palmitate is an ester formed by the reaction of dextrin, a carbohydrate derived from the hydrolysis of starch, with palmitic acid, a fatty acid. This compound is commonly used in the cosmetics and personal care industry due to its multifunctional properties. As an emulsifier, dextrin palmitate helps to stabilize and blend oil and water-based ingredients, ensuring a smooth and consistent texture in products such as creams, lotions, and makeup. Additionally, it serves as a thickening agent, enhancing the viscosity and providing a desirable creamy or gel-like texture. Its moisturizing properties help retain skin moisture, improving hydration and overall skin feel. Dextrin palmitate is valued for its ability to enhance the stability, performance, and sensory attributes of various cosmetic formulations, making it a popular choice for formulators looking to create high-quality skincare and beauty products. Synonyms: Dextrin, hexadecanoate; Leo Pearl KL 2; Rheopearl FL; Rheopearl KE; Rheopearl KEKL; Rheopearl KL; Rheopearl KL 2; Rheopearl KL2-OR; Rheopearl KS 2; Rheopearl TL; Rheopearl TL 2. CAS No. 83271-10-7. | |
| Diguanylate Cyclase from Agrobacterium vitis, recombinant | The diguanylate cyclase from Agrobacterium vitis has been engineered to remove phosphodiesterase activity, allowing for production of cyclic-diGMP from guanosine triphosphate (GTP) without the production of 5'-phosphoguanylyl-(3',5')-guanosine (pGpG). Applications: Useful for producing cyclic-digmp from gtp without production of pgpgcompletely lacks unwanted phosphodiesterase activityno product inhibition even at high concentrations of gtpremains active while immobilized to solid resin and retain enzymatic activity after several months of storagecan be used to synthesize radiolabeled cyclic digmp from radiolabeled gtp. Group: Enzymes. Synonyms: DGC; PleD; EC 2.7.7.65; 146316-82-7; Engineered Diguanylate Cyclase. Enzyme Commission Number: EC 2.7.7.65. CAS No. 146316-82-7. Purity: >99% based on SDS-PAGE analysis with coomassie blue. Mole weight: 56 kDa. Activity: 7.5 nmol min-1. Storage: at -80 °C; Multiple freeze/thaw cycles are not recommended. Form: Liquid. Source: E. coli. Species: Agrobacterium vitis. Diguanylate cyclase; DGC; PleD; EC 2.7.7.65; 146316-82-7; Engineered Diguanylate Cyclase. Cat No: NATE-1692. | |
| Dimercaprol | It was developed as an experimental antidote against the arsenic-based poison gas Lewisite. It has been used clinically since 1949 in arsenic, cadmium and mercury poisoning. In addition, it has in the past been used for the treatment of Wilson's disease, a genetic disorder in which the body tends to retain copper. Dimercaprol has toxic potential, and its use may be followed by a variety of adverse effects. Alternative Names: DIMERCAPROL. 2,3-Dimercapto-1-propanol. 2,3-Dimercaptopropanol. Dithioglycerine. CAS No. 59-52-9. Product ID: API59529. Molecular formula: C3H8OS2. Mole weight: 124.23. EINECS: 200-433-7. SMILES: C(C(CS)S)O. Appearance: clear colorless viscous liquid. Category: APIs for Antidote. |  |
| Dolutegravir | Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC 50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC 50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC 50 =3.6-5.8 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S/GSK1349572. CAS No. 1051375-16-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-13238. | |
| Dolutegravir sodium | Dolutegravir sodium (S/GSK1349572 sodium) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC 50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir sodium (S/GSK1349572 sodium) inhibits HIV-1 viral replication with an IC 50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir sodium (S/GSK1349572 sodium) retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC 50 =3.6-5.8 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: S/GSK1349572 sodium. CAS No. 1051375-19-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13238A. | |
| Ds(+)-threo-Isocitric acid trisodium salt | Anticoagulant that retains platelets functionality. Buffers Ca2+ activity in physiological range (~1mM). Bypasses the metabolic blockade, may permit heme biosynthesis but does not suffice to reverse the iron-restriction response. Stabilizes the iron-sulfur cluster and is predicted to restore aconitase to its 'high iron' conformation and thereby dissociates the PKC-associated signaling complexes whose hyperactivation impairs Epo responsiveness. Binds IDH (isocitrate dehydrogenase), an excellent candidate for participating, along with aconitase and PKC, in an iron restriction signalosome. Contributes to heme biosynthesis which may account for its greater potency in restoring erythroid differentiation. Group: Biochemicals. Alternative Names: (1R,2S)-1-Hydroxy-1,2,3-propanetricarboxylic acid; (2R,3S)-Isocitric acid trisodium salt. Grades: Highly Purified. CAS No. 903507-52-8. Pack Sizes: 25mg, 100mg. Molecular Formula: C6H5O7 3Na, Molecular Weight: 258.1. US Biological Life Sciences. | Worldwide |
| Elomotecan | Elomotecan (BN-80927) belongs to a novel family of camptothecin analogs, the homocamptothecins, developed on the concept of topoisomerase I (Topo I) inhibition and characterized by a stable seven-membered beta-hydroxylactone ring. Preclinical data reported here show that BN80927 retains Topo I poisoning activity in cell-free assay (DNA relaxation) as well as in living cells, in which in vivo complexes of topoisomerase experiments and quantification of DNA-protein-complexes stabilization, have confirmed the higher potency of BN80927 as compared with the Topo I inhibitor SN38. In addition, BN80927 inhibits Topo II-mediated DNA relaxation in vitro but without cleavable-complex stabilization, thus indicating catalytic inhibition. Moreover, a Topo I-altered cell line (KBSTP2), resistant to SN38, remains sensitive to BN80927, suggesting that a part of the antiproliferative effects of BN80927 are mediated by a Topo I-independent pathway. This hypothesis is also supported by in vitro data showing an antiproliferative activity of BN80927 on a model of resistance related to the noncycling state of cells (G(0)-G(1) synchronized). In cell growth assays, BN80927 is a very potent antiproliferative agent as shown by IC(50) values consistently lower than those of SN38 in tumor cell lines as well as in their related drug-resistant lines. BN80927 shows high efficiency in vivo in tumor xenograft studies using human androgen-independent prostate | |
| ELR510444 | ELR510444 is a potent microtube disruptor with potential anticancer activity. ELR510444 has potent microtubule-disrupting activity, causing a loss of cellular microtubules and the formation of aberrant mitotic spindles and leading to mitotic arrest and apoptosis of cancer cells. ELR510444 potently inhibited cell proliferation with an IC(50) value of 30.9 nM in MDA-MB-231 cells, inhibited the rate and extent of purified tubulin assembly, and displaced colchicine from tubulin, indicating that the drug directly interacts with tubulin at the colchicine-binding site. ELR510444 is not a substrate for the P-glycoprotein drug transporter and retains activity in βIII-tubulin-overexpressing cell lines, suggesting that it circumvents both clinically relevant mechanisms of drug resistance to this class of agents. ELR510444 also shows potent antitumor activity in the MDA-MB-231 xenograft model with at least a 2-fold therapeutic window. Synonyms: ELR510444; ELR-510444; ELR 510444. Grade: >98%. CAS No. 1233948-35-0. Molecular formula: C19H16N2O2S2. Mole weight: 368.47. | |
| Enzyme blend for dough | Powder enzyme blend used in flour, pre-mixes and bread improvers to reduce viscosity of dough gluten/pentosan complexes.It enhances dough-rising capacity, increases loaf volume, and improves crumb structure. Applications: Retain freshness. Group: Enzymes. Synonyms: dough; Enzyme blend for dough; Retain Freshness; flour enzyme; enhances dough-rising; enhances dough-rising capacity enzyme; increases loaf volume enzyme; loaf volume; BAK-1717. Enzyme for dough. Appearance: powder or liquid. dough; Enzyme blend for dough; Retain Freshness; flour enzyme; enhances dough-rising; enhances dough-rising capacity enzyme; increases loaf volume enzyme; loaf volume; BAK-1717. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: BAK-1717. | |
| ER-Tracker Green | ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K+ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation[1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 730931-46-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1297. | |
| ER-Tracker Red | ER-Tracker dye is a derivative of BODIPY series dyes coupled with Glibenclamide (HY-15206), highly selective binding to the endoplasmic reticulum, non-toxic to cells at low concentrations, this type of dye is an environmentally sensitive probe, and formaldehyde treatment can still retain part of the fluorescence, with high fluorescence life, good extinction coefficient and other characteristics. Glibenclamide is an atp-dependent K+ channel blocker (Kir6, KATP) and CFTR Cl-channel blocker that binds in the endoplasmic reticulum. ER-Tracker is not suitable for staining cells after fixation. Ex/Em=587/615 nm[1]. Uses: Scientific research. Group: Fluorescent dye. Pack Sizes: 50 ?g; 100 ?g. Product ID: HY-D1431. | |
| EUK-134 (chloro[[2, 2'- [1, 2- ethanediylbis[(nitrilo- κ N)methylidyne]]bis[6- methoxyphenolato- κO]]]- manganese) | A synthetic superoxide dismutase (SOD)/catalase mimetic. EUK 134 is a salen-manganese complex that has been modified to increase its catalase activity while retaining SOD activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 81065-76-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Fructose | Fructose occurs as odorless, colorless crystals or a white crystalline powder with a very sweet taste. Synonyms: Advantose FS 95; D-arabino-2-hexulose; Fructamyl; Fructofin; D-(-)-fructopyranose; b-D-fructose; fructosum; fruit sugar; Krystar; laevulose; levulose; nevulose. CAS No. 57-48-7. Product ID: PE-0420. Molecular formula: C6H12O6. Mole weight: 180.16. Category: flavoring Agents; Sweetening Agents; Diluent. Product Keywords: Flavoring Agents; Stabilizers; PE-0420; Fructose; flavoring Agents; Sweetening Agents; Diluent; C6H12O6; 57-48-7. UNII: 6YSS42VSEV. Chemical Name: D-Fructose. Grade: Pharmceutical Excipients. Administration route: Intravenous, oral, rectal. Dosage Form: Oral solutions; syrup, and suspensions; rectal preparations; intravenous infusions. Stability and Storage Conditions: Fructose is hygroscopic and absorbs significant amounts of moisture at relative humidities greater than 60%. Goods stored in the original sealed packaging at temperatures below 25°C and a relative humidity of less than 60% can be expected to retain stability for at least 12 months. Aqueous solutions are most stable at pH 3-4 and temperatures of 4-70°C; they may be sterilized by autoclaving. Source and Preparation: Fructose, a monosaccharide sugar, occurs naturally in honey and a large number of fruits. It may be prepared from inulin, dextrose, or sucrose by a number of methods. Commercially, fructose is mainly manufactured by crysta | |
| FTY720 phenoxy-biotin | FTY720 is a potent agonist at four of the five sphingosine-1-phosphate (S1P) receptors. Biotin-FTY720 is a biotin-tagged analog of FTY720. The hydroxy methyl side chain of FTY720 that is targeted for phosphorylation by sphingosine kinases is retained in this analog, which means that it would likewise be phosphorylated in vivo. Synonyms: 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol-N-biotinoyl-1,5-diampentane. Grade: ≥95%. Molecular formula: C27H44N4O5S·HCl. Mole weight: 573.2. | |
| GNE-9605 | GNE-9605 retained excellent predicted human metabolic stability when assayed in human liver microsomes and hepatocytes. In addition, no reversible or time-dependent inhibition of any of the major CYP isoforms was observed. The demonstrated metabolic stability, brain penetration across multiple species, and selectivity of these inhibitors support their use in preclinical efficacy and safety studies. Synonyms: GNE9605; GNE-9605; GNE 9605. Grade: 0.98. CAS No. 1536200-31-3. Molecular formula: C17H20ClF4N7O. Mole weight: 449.839. | |
| GSK321 | GSK321 is a highly potent, selective inhibitor of mutant IDH1 enzymes, with IC50=4.6 nM against R132H, 3.8 nM against R132C and 2.9 nM against R132G. GSK321 stably decreased 2-hydroxyglutarate (2-HG) production in several different IDH1 mutant AML cells within a 2-3 week time frame ex vivo. Because of the allosteric nature of the interaction, GSK321 is able to inhibit multiple mutant forms of IDH1, which is consistent with our cell biological observations. Furthermore, GSK321 retains excellent potency in cells, since it does not compete with the tightly bound cofactor. Synonyms: (7R)-1-[(4-fluorophenyl)methyl]-N-[3-[(1S)-1-hydroxyethyl]phenyl]-7-methyl-5-(1H-pyrrole-2-carbonyl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-3-carboxamide; (7R)-1-[(4-fluorophenyl)methyl]-N-[3-[(1S)-1-hydroxyethyl]phenyl]-7-methyl-5-(1H-pyrrole-2-carbonyl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-3-carboxamide; GSK321; GSK 321; GSK-321; BDBM195601. Grade: >98%. CAS No. 1816331-63-1. Molecular formula: C28H28FN5O3. Mole weight: 501.56. | |
| Hyaluronic acid, acetate (ester) | Hyaluronic acid, acetate (ester), is a modified form of hyaluronic acid where some carboxyl groups are esterified with acetic acid. This derivative is used in cosmetics for its ability to retain moisture, promote skin repair, and reduce the appearance of aging. It enhances skin hydration, improves elasticity, and may facilitate better absorption through the skin. Additionally, it serves as a viscosity control agent and a film-former, providing a protective barrier and locking in moisture. Synonyms: AcHa; Acetylated hyaluronate; Hyaluronate acetate; Hyaluronic acid, acetate. Grade: ≥95%. CAS No. 158254-23-0. | |
| Hymetellose328 | Hymetellose328. Synonyms: Methylhydroxyethylcellulose; Cellulose; 2-hydroxyethyl methyl ether; HEMC; Tyopur MH. CAS No. 9032-42-2. Product ID: PE-0540. Molecular formula: C2H6O2·xCH4O·x. Category: Pore-forming Agents; Coating Agents; Thickener; Suspending Agents; Dispersing Agents; Binding Agents; Emulsifier; Film-forming Agents; Water-retaining Agents. Product Keywords: Excipients for Liquid Dosage Form; Emulsifier Excipients; PE-0540; Hymetellose328; Pore-forming Agents; Coating Agents; Thickener; Suspending Agents; Dispersing Agents; Binding Agents; Emulsifier; Film-forming Agents; Water-retaining Agents; C2H6O2·xCH4O·x; 9032-42-2. UNII: 0MGW7Q3QG4. Chemical Name: Hydroymethylmethylecellulose. Grade: Pharmceutical Excipients. Administration route: Oral, optical. Dosage Form: Oral suspensions, tablets and topical formulations. Stability and Storage Conditions: Hydroxymethylcellulose is hygroscopic and should be stored in a cool, dry place. Applications: 1.Pharmacy As a hydrophilic gel matrix material, porogen, and coating agent for the preparation of sustained-release preparations. It can also be used as a thickening, suspending, dispersing, binding, emulsifying, film-forming, and water-retaining agent for preparations. 2. Food processing can also be used as, adhesive, emulsifying, film-forming, thickening, suspending, dispersing, water-retaining agent, etc. 3. In the daily chemical industry, it is used as an addi | |
| Immobilized human plasmin | We have immobilized human Lys plasmin on agarose resin by coupling of primary amines. Plasmin retains catalytic activity when coupled and may be used to efficiently activate single-chain tPA and uPA to the two-chain form. It may also be used to convert plasminogen from its native Glu form to the Lys form by removing the first 77 amino acids. Group: Enzymes. Synonyms: fibrinase; fibrinolysin; actase; serum tryptase; thrombolysin; plasmin; EC 3. 4. 21. 7; 9001-90-5; PLG. Enzyme Commission Number: EC 3. 4. 21. 7. Purity: >95% by SDS-PAGE analysis. Mole weight: 85000. Stability: 12 months from delivery. Storage: 4°C. Form: Resin. Source: Human plasma. Species: Human. fibrinase; fibrinolysin; actase; serum tryptase; thrombolysin; plasmin; EC 3. 4. 21. 7; 9001-90-5; PLG; Immobilized plasmin. Cat No: NATE-1757. | |
| inulin fructotransferase (DFA-I-forming) | This enzyme, like EC 4.2.2.16 [levan fructotransferase (DFA-IV-forming)] and EC 4.2.2.18 [inulin fructotransferase (DFA-III-forming)] eliminates the fructan chain from the terminal disaccharide leaving a difructose dianhydride. These enzymes have long been known as fructotransferases, so this is retained in the accepted name. Since the transfer is intramolecular, the reaction is an elimination and, hence, the enzyme is a lyase, belonging in EC 4. Group: Enzymes. Synonyms: inulin fructotransferase (DFA-I-producing); inulin fructotransferase (depolymerizing, difructofuranose-1,2':2',1-dianhydride-forming); inulin D-fructosy. Enzyme Commission Number: EC 4.2.2.17. CAS No. 125008-19-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5092; inulin fructotransferase (DFA-I-forming); EC 4.2.2.17; 125008-19-7; inulin fructotransferase (DFA-I-producing); inulin fructotransferase (depolymerizing, difructofuranose-1,2':2',1-dianhydride-forming); inulin D-fructosyl-D-fructosyltransferase (1,2':1',2-dianhydride-forming); inulin D-fructosyl-D-fructosyltransferase (forming α-D-fructofuranose β-D-fructofuranose 1,2':1',2-dianhydride); 2,1-β-D-fructan lyase (α-D-fructofuranose-β-D-fructofuranose-1,2':2,1'-dianhydride-forming). Cat No: EXWM-5092. | |
| inulin fructotransferase (DFA-III-forming) | This enzyme, like EC 4.2.2.16 [levan fructotransferase (DFA-IV-forming)] and EC 4.2.2.17 [inulin fructotransferase (DFA-I-forming)] eliminates the fructan chain from the terminal disaccharide leaving a difructose dianhydride. These enzymes have long been known as fructotransferases, so this is retained in the accepted name. Since the transfer is intramolecular, the reaction is an elimination and, hence, the enzyme is a lyase, belonging in EC 4. Group: Enzymes. Synonyms: inulin fructotransferase (DFA-III-producing); inulin fructotransferase (depolymer. Enzyme Commission Number: EC 4.2.2.18. CAS No. 50936-42-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5093; inulin fructotransferase (DFA-III-forming); EC 4.2.2.18; 50936-42-0; inulin fructotransferase (DFA-III-producing); inulin fructotransferase (depolymerizing); inulase II; inulinase II; inulin fructotransferase (depolymerizing, difructofuranose-1,2':2,3'-dianhydride-forming); inulin D-fructosyl-D-fructosyltransferase (1,2':2,3'-dianhydride-forming); inulin D-fructosyl-D-fructosyltransferase (forming α-D-fructofuranose β-D-fructofuranose 1,2':2,3'-dianhydride); 2,1-β-D-fructan lyase (α-D-fructofuranose-β-D-fructofuranose-1,2':2,3'-dianhydride-forming). Cat No: EXWM-5093. | |
| Isomalt | Isomalt. Synonyms: Hydrogenated isomaltulose; hydrogenated palatinose. CAS No. 64519-82-0. Product ID: PE-0494. Category: Sweetening agent. Product Keywords: Pharmaceutical Excipients; Excipients for Solid Dosage Form; Isomalt; Sweeteners Excipients; Sweetening agent; 64519-82-0; 64519-82-0. UNII: S870P55O2W. Stability and Storage Conditions: Isomalt has very good thermal and chemical stability. When it is melted, no changes in the molecular structure are observed. It exhibits considerable resistance to acids and microbial influences.Isomalt is non-hygroscopic, and at 25°C does not significantly absorb additional water up to a relative humidity (RH) of 85%; paracetamol (acetaminophen) tablets based on isomalt were stored for 6 months at 85% RH at 208C and retained their physical aspect. If stored under normal ambient conditions, isomalt is chemically stable for many years. When it is stored in an unopened container at 20°C and 60% RH, a re-evaluation after 3 years is recommended. Isomalt does not undergo browning reactions; it has no reducing groups, and therefore it does not react with other ingredients in a formulation (e.g. with amines in Maillard reactions). Source and Preparation: Isomalt is produced from food-grade sucrose in a two-stage process.Beet sugar is converted by enzymatic transglucosidation into the reducing disaccharide isomaltulose. This undergoes catalytical hydrogenation to produce isomalt. Safety: Isomal | |
| κ-Carrageenase from Zobellia galactanivorans, Recombinant | Kappa-carrageenase (EC 3.2.1.83, kappa-carrageenan 4-beta-D-glycanohydrolase) is an enzyme with systematic name kappa-carrageenan 4-beta-D-glycanohydrolase (configuration-retaining). This enzyme catalyses the following chemical reaction: Endohydrolysis of (1->4)-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans. The main products of hydrolysis are neocarrabiose-sulfate and neocarratetraose-sulfate. Group: Enzymes. Synonyms: K-Carrageenase; Kappa-carrageenase; EC 3.2.1.83; kappa-carrageenan 4-beta-D-glycanohydrolase. Enzyme Commission Number: EC 3.2.1.83. CAS No. 37288-59-8. Purity: >90% by SDS-PAGE. κ-carrageenase. Mole weight: 34.2 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Zobellia galactanivorans. K-Carrageenase; Kappa-carrageenase; EC 3.2.1.83; kappa-carrageenan 4-beta-D-glycanohydrolase. Cat No: NATE-1292. | |
| Klemm's Reagent | For etching alpha-beta brass, bonze, tin, cast iron phosphides, ferrite, martensite, retained austenite, zinc and steel temper embrittlement. Group: Etchants. | |
| levan fructotransferase (DFA-IV-forming) | This enzyme, like EC 4.2.2.17 [inulin fructotransferase (DFA-I-forming)] and EC 4.2.2.18 [inulin fructotransferase (DFA-III-forming)] eliminates the fructan chain from the terminal disaccharide leaving a difructose dianhydride. These enzymes have long been known as fructotransferases, so this is retained in the accepted name. Since the transfer is intramolecular, the reaction is an elimination and, hence, the enzyme is a lyase, belonging in EC 4. Group: Enzymes. Synonyms: 2,6-β-D-fructan D-fructosyl-D-fructosyltransferase (forming di-β-D-fructofuranose 2,6':2',6-dianhydride); levan fructotransferase; 2,6-β-D-fructan lyase (di-β-D-fructofuranose-2,6':2',6-dianhydride-forming). Enzyme Commission Number: EC 4.2.2.16. CAS No. 88593-15-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5091; levan fructotransferase (DFA-IV-forming); EC 4.2.2.16; 88593-15-1; 2,6-β-D-fructan D-fructosyl-D-fructosyltransferase (forming di-β-D-fructofuranose 2,6':2',6-dianhydride); levan fructotransferase; 2,6-β-D-fructan lyase (di-β-D-fructofuranose-2,6':2',6-dianhydride-forming). Cat No: EXWM-5091. | |
| Lysipressin Acetate | Lysipressin Acetate is a lysine vasopressin, which retains water in the body and constricts blood vessels. Synonyms: Vasopressin, 8-L-lysine-, monoacetate (salt); Des-(1-3)-terlipressin acetate salt; Terlipressin EP Impurity C acetate salt; Des-Gly1-Gly2 Gly3 Terlipressin acetate salt; H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2.C2H4O2 (Disulfide bridge: Cys1-Cys6); L-Cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide (1->6)-disulfide acetate salt; Des-1,2,3-Triglycine-Terlipressin acetate salt; 8-L-Lysine vasopressin acetate salt; L-Lysine vasopressin acetate salt; Vasopressin-8-lysine acetate salt. Grade: ≥95%. CAS No. 83968-49-4. Molecular formula: C48H69N13O14S2. Mole weight: 1116.27. | |
| Methoxy-X04 | Methoxy-X04 is a fluorescent dye that crosses the blood-brain barrier and selectively binds to beta-pleated sheets found in dense core amyloid Aβ plaques. Methoxy-X04 retains in vitro binding affinity for amyloid b (Ab) fibrils ( K i = 26.8 nM). Methoxy-X04 is fluorescent and stains plaques, tangles, and cerebrovascular amyloid in postmortem sections of AD brain with good specificity [1] [2]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 863918-78-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103240. | |
| Methylation modified Trypsin from Porcine, Recombinant | Trypsin specifically hydrolyzes peptide bonds at the carboxyl side of lysine and arginine residues. Recombinant trypsin is free of any other proteases activities, and TPCK is unnecessary and not contained. Unmodified trypsin is subject to auto-proteolysis, generating fragments that can interfere with protein sequencing or HPLC/MS peptides analysis. Sequencing grade modified trypsin is recombinant porcine trypsin modified by reductive methylation, rendering it resistant to proteolytic digestion. Applications: Protein digests for peptide mapping applications or protein identification by peptide mass fingerprinting or ms/ms spectral matching. it is suitable for digest.under -70°C, It is stable within 24 months.2. Above 95% activity is remained after 5 times repeated freezing and thawing.3. Above 90% activity is remained after kept under 4°C or 25°C for 24h.4. A 0.05 mg/ml solution of sequencing grade modified recombinant trypsin in 50mM NH4HCO3 is retained above 95% after a 3 hours incubation at 37 °C. For long-term such as 20hours incubation, 1mM CaCl2 is recommended to be contained. Form: Lyophilized. Source: E. coli. Species: Porcine. α-trypsin; β-trypsin; cocoonase; parenzyme; parenzymol; tryptar; trypure; pseudotrypsin; tryptase; tripcellim; sperm receptor hydrolase; Alpha-trypsin; Beta-trypsin; EC 3.4.21.4; Tryp. | |
| MK-2048 | MK-2048 represents a prototype second generation integrase strand transfer inhibitor (INSTI), it was developed with the goal of retaining activity against viruses containing mutations assiciated with resistance of first-generation INSTIs, raltegravir. MK-2048 exhibits inhibitory activity towards HIV integrase and towards HIV replication. It is four times more effective in inhibiting HIV enzyme integrase than the first generation inhibitor, raltegravir. Group: Biochemicals. Alternative Names: (6S)-2-(3-Chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N, 6-dimethyl-1, 9-dioxo-1, 2, 6, 7, 8, 9-hexahydropyrazino[1', 2':1, 5]pyrrolo[2, 3-d]pyridazine-4-carboxamide. Grades: Highly Purified. CAS No. 869901-69-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| MT1-MMP Inhibitor, NSC405020 (3,4-Dichloro-N-(1-methylbutyl)benzamide, 3,4-Dichloro-N-(pentan-2-yl)benzamide) | A cell-permeable pentanylbenzamide compound that acts as an allosteric, reversible, and selective inhibitor of the collgenolytic activity of MT1-MMP. Does not affect the catalytic activity of cellular MT-1-MMP thus allows it to retain its ability to activate MMP-2. Selectively targets the hemopexin (PEX) domain of MT1-MMP, thereby repressing its pro-tumorigenic activity. Its binding to the PEX domain is dependent on Met-328, Arg-330, Asp-376, Met-422, and Ser-470 in the druggable pocket of the enzyme. Shown to block 184B5-MT cell migration on collagen-1 and repress MCF7-b3/MT tumor growth in xenografted mice (0.5mg/kg, intratumoral). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
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