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| Product | Description | |
|---|---|---|
| RGD | RGD is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins. Uses: Scientific research. Group: Peptides. CAS No. 99896-85-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0278. |  |
| RGD-4C | RGD-4C preferentially binds to integrins αvβ3 and αvβ5, both of which are overexpressed in many cancers, such as non-small cell lung cancer, melanoma, and growing vessels. Synonyms: H-Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly-OH (Disulfide bridge: Cys2-Cys10, Cys4-Cys8); L-alanyl-L-cysteinyl-L-alpha-aspartyl-L-cysteinyl-L-arginyl-glycyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-cysteinyl-glycine (2->10),(4->8)-bis(disulfide); N-{[(1R,4S,7R,12R,15S,18R,21S,27S)-7-(L-Alanylamino)-15-benzyl-27-(3-carbamimidamidopropyl)-4,21-bis(carboxymethyl)-3,6,14,17,20,23,26,29-octaoxo-9,10,31,32-tetrathia-2,5,13,16,19,22,25,28-octaazabicyclo[16.11.4]tritriacont-12-yl]carbonyl}glycine. Grades: ≥95%. CAS No. 332179-76-7. Molecular formula: C42H60N14O16S4. Mole weight: 1145.29. |  |
| RGD Negative Control | It is the negative control of c(RGDfE). Synonyms: c(RADfE); cyclo[Ala-Asp-D-Phe-Glu-Arg]; cyclo[L-alanyl-L-alpha-aspartyl-D-phenylalanyl-L-alpha-glutamyl-L-arginyl]. Grades: ≥95%. CAS No. 756500-24-0. Molecular formula: C27H38N8O9. Mole weight: 618.65. | |
| RGD peptide | RGD peptide is an inhibitor of integrin-ligand interactions. Synonyms: H-Gly-Arg-Gly-Asp-Asn-Pro-OH; RGD peptide (GRGDNP); glycyl-L-arginyl-glycyl-L-alpha-aspartyl-L-asparagyl-L-proline; (S)-1-((6S,12S,15S)-1-amino-15-(2-amino-2-oxoethyl)-6-(2-aminoacetamido)-12-(carboxymethyl)-1-imino-7,10,13-trioxo-2,8,11,14-tetraazahexadecane)pyrrolidine-2-carboxylic acid. Grades: 98%. CAS No. 114681-65-1. Molecular formula: C23H38N10O10. Mole weight: 614.61. | |
| RGD peptide (GRGDNP) | RGD peptide (GRGDNP) is an inhibitor of integrin-ligand interactions. RGD peptide (GRGDNP) competitively inhibits α5β1 binding with extracellular matrice (ECM). RGD peptide (GRGDNP) promotes apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing. RGD peptide (GRGDNP) plays an important role in cell adhesion, migration, growth, and differentiation [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 114681-65-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1740. | |
| RGD-targeted Proapoptotic Peptide | RGD-targeted Proapoptotic Peptide is RGD-4C conjugated to a full D proapoptotic peptide. Synonyms: RGD-4C-GG-(klaklak)2-NH2; H-Ala-Cys-Asp-Cys-Arg-Gly-Asp-Cys-Phe-Cys-Gly-Gly-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-D-Lys-D-Leu-D-Ala-D-Lys-D-Leu-D-Ala-D-Lys-OH (Disulfide bridge: Cys2-Cys10, Cys4-Cys8); D-Lysine, L-alanyl-L-cysteinyl-L-α-aspartyl-L-cysteinyl-L-arginylglycyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-cysteinylglycylglycyl-D-lysyl-D-leucyl-L-alanyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-lysyl-D-leucyl-D-alanyl-D-lysyl-D-leucyl-D-alanyl-, cyclic(2?10),(4?8)-bis(disulfide). Grades: ≥95%. CAS No. 2243207-09-0. Molecular formula: C116H199N35O31S4. Mole weight: 2708.34. | |
| RGD Trifluoroacetate | RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; RGD Trifluoroacetate binds to integrins. Uses: Scientific research. Group: Peptides. CAS No. 2378808-45-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0278A. | |
| Alginate-RGD bioink | Alginate-RGD bioink. Group: 3d printing materials. |  |
| Cellulose-Alginate-RGD bioink | Cellulose-Alginate-RGD bioink. Group: 3d printing materials. | |
| CGGRGD acetate | CGGRGD acetate is a RGD derivative with cysteine as the n-terminal. CGGRGD was synthesized by solid phase peptide synthesis technology, and amino2-cyanobenzothiazole (2-cyanobenzothiazole) (2-cyanobenzothiazole (CBT) was added on the surface of PCL fiber for ammoniation. Molecular formula: C21H37N9O11S. Mole weight: 623.65. | |
| c(RGDfK) | Cyclo (-RGDfK) is a potent and selective αvβ3 integrin inhibitor. Grades: 98%. CAS No. 161552-03-0. Molecular formula: C27H41N9O7. Mole weight: 603.67. | |
| cyclo[RGD(DMNPB)fK] | cyclo[RGD(DMNPB)fK], a photosensitive caged RGD peptide, is used for efficient phototriggering of cell attachment. Synonyms: Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-lysyl), 2-(4,5-dimethoxy-2-nitrophenyl)-1-methylpropyl ester. CAS No. 1035105-00-0. Molecular formula: C39H56N10O11. Mole weight: 840.94. | |
| Cyclo(RGDfC) acetate | Cyclo(RGDfC) acetate is a potent and selective inhibitor of the αvβ3 integrin receptor. Synonyms: Cyclo(-RGDfC) acetate; cyclo[Arg-Gly-Asp-D-Phe-Cys] acetate; cyclo[L-arginyl-glycyl-L-alpha-aspartyl-D-phenylalanyl-L-cysteinyl] acetic acid; Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-cysteinyl) acetate. Grades: ≥95%. CAS No. 2171504-31-5. Molecular formula: C26H38N8O9S. Mole weight: 638.69. | |
| Cyclo(-RGDfK) | Cyclo(-RGDfK) Inhibitor. Uses: Scientific use. Product Category: T6812. CAS No. 161552-03-0. |  |
| Cyclo(RGDyC) | Cyclo(RGDyC) is a cyclic pentapeptide with anti-angiogenic abilities. Cyclo(RGDyC) can be combined with liposome delivery systems for research on ocular neovascular diseases and cancer [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 1206475-79-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5840. | |
| cyclo(RGDyC) acetate | Cyclo(RGDyC) acetate, a cyclic RGDyc sequence, is an integrin avb3-affine polypeptide. Synonyms: Cyclo(-RGDyC) acetate; cyclo[L-arginyl-glycyl-L-alpha-aspartyl-D-tyrosyl-L-cysteinyl] acetate; Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-cysteinyl) acetate. Grades: ≥95%. Molecular formula: C26H38N8O10S. Mole weight: 654.70. | |
| Cyclo(RGDyK)-Cy5.5 | Synonyms: Cyclo(Arg-Gly-Asp-D-Tyr-Lys)-Cy5.5; c(RGDyK)-Cy5.5; Cyclo[L-arginylglycyl-L-α-aspartyl-D-tyrosyl-N6-[6-[2-[5-(3-ethyl-1,3-dihydro-1,1-dimethyl-6,8-disulfo-2H-benz[e]indol-2-ylidene)-1,3-pentadien-1-yl]-1,1-dimethyl-6,8-disulfo-1H-benz[e]indolio]-1-oxohexyl]-L-lysyl], inner salt; RGD-Cy 5.5. CAS No. 820967-21-3. Molecular formula: C68H83N11O21S4. Mole weight: 1518.71. | |
| Cyclo(RGDyK) Trifluoroacetate | Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM. Synonyms: Cyclo (RGDyK); Cyclo RGDyK; Cyclo(RGDyK) trifluoroacetate. Grades: >98%. CAS No. 250612-42-1. Molecular formula: C31H43F6N9O12. Mole weight: 847.71. | |
| GRGDSP | GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor which can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization. Synonyms: H-Gly-Arg-Gly-Asp-D-Ser-Pro-OH; glycyl-L-arginyl-glycyl-L-alpha-aspartyl-D-seryl-L-proline. Grades: ≥95%. CAS No. 91037-75-1. Molecular formula: C22H37N9O10. Mole weight: 587.58. | |
| GRGDSP acetate | GRGDSP acetate, a synthetic linear RGD peptide, is an integrin inhibitor that can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization. Synonyms: H-Gly-Arg-Gly-Asp-Ser-Pro-OH.CH3CO2H; Glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-proline acetic acid; L-Proline, 1-[N-[N-[N-(N2-glycyl-L-arginyl)glycyl]-L-α-aspartyl]-L-seryl]-, acetate. Grades: ≥95%. Molecular formula: C24H41N9O12. Mole weight: 647.64. | |
| GRGDSPK | GRGDSPK is a competitive and reversible inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules. Synonyms: EMD 56574; H-Gly-Arg-Gly-Asp-Ser-Pro-Lys-OH; glycyl-L-arginyl-glycyl-L-alpha-aspartyl-L-seryl-L-prolyl-L-lysine; N2-(1-(N-(N-(N-(N2-Glycyl-L-arginyl)glycyl)-L-alpha-aspartyl)-L-seryl)-L-prolyl)-L-lysine. Grades: 95%. CAS No. 111119-28-9. Molecular formula: C28H49N11O11. Mole weight: 715.76. | |
| NODAGA-RGD | NODAGA-RGD is a peptide that can be radiolabeled and used as a radiotracer for positron emission tomography (PET) diagnosis [1]. Uses: Scientific research. Group: Peptides. CAS No. 1321510-77-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10734. | |
| (1R, 3S) -3-Aminocyclopentane carboxylic Acid | (1R, 3S) -3-Aminocyclopentane carboxylic Acid is used in the synthesis of aminocyclopentane carboxylic acid-containing cyclic RGD peptides. It is also used to prepare BMS-457, a potent and selective CCR1 antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 71830-08-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C6H11NO2, Molecular Weight: 129.16. US Biological Life Sciences. |  Worldwide |
| 2-(2-Boc-aminoethoxy)ethanol | 2-(2-Boc-aminoethoxy)ethanol is a reactant that has been used in the synthesis of RGD-conjugated MEK1/2 kinase inhibitors for integrin-targeted cancer therapy. Group: Biochemicals. Grades: Highly Purified. CAS No. 139115-91-6. Pack Sizes: 1g, 5g. Molecular Formula: C9H19NO4. US Biological Life Sciences. | Worldwide |
| 2,3,4,6-Tetra-O-acetyl-a-D-glucopyranose | 2,3,4,6-Tetra-O-acetyl-a-D-glucopyranose is a lynchpin in the some synthesis process of various glycosylation pharmaceuticals. Specifically, in fabricating antiviral regimes such as Tenofovir, it proves to be indispensable. Synonyms: 2,3,4,6-Tetra-O-acetyl-a-D-glucopyranose; 6207-76-7; 2,3,4,6-Tetra-o-acetyl-alpha-D-glucopyranose; [(2R,3R,4S,5R,6S)-3,4,5-triacetyloxy-6-hydroxyoxan-2-yl]methyl acetate; SCHEMBL1140728; IEOLRPPTIGNUNP-RGDJUOJXSA-N; 2,3,4,6-tetra-O-acetyl-alpha-D-glucose; alpha-d-glucopyranose-2,3,4,6-tetraacetate; W-203318. CAS No. 6207-76-7. Molecular formula: C14H20O10. Mole weight: 348.3. | |
| Arg-Gly-Asp | RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins. Synonyms: Arginyl-Glycyl-Aspartic acid; RGD peptide. Grades: Min 98%. CAS No. 99896-85-2. Molecular formula: C12H22N6O6. Mole weight: 346.34. | |
| Arg-Gly-Asp-Cys acetate | Arg-Gly-Asp-Cys, a fibronectin binding motif to cell adhesion molecules, inhibits platelet aggregation and fibrinogen binding. Synonyms: L-arginyl-glycyl-L-alpha-aspartyl-L-cysteine; RGDC peptide. Molecular formula: C17H31N7O9S. Mole weight: 509.54. | |
| Arg-Gly-Asp-Ser | Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. It is a tetrapeptide found on fibronectin, fibrinogen α, and von Willebrand factor, but not vitronectin or collagen. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9. It inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor. It promotes cell attachment and abrogates apoptosis via the mitochondrial pathway in osteoblasts in vitro. It also blocks the attachment of certain pathogens to cells. Uses: Platelet aggregation inhibitors. Synonyms: Arg Gly Asp Ser; RGDS peptide; Fibronectin Inhibitor. Grades: >98%. CAS No. 91037-65-9. Molecular formula: C15H27N7O8. Mole weight: 433.42. | |
| Arg-Gly-Asp TFA salt | Arg-Gly-Asp can be used as a brain tumor targeting ligand. Synonyms: RGD (Trifluoroacetate); RGD Trifluoroacetate; HY-P0278A. Grades: ≥98%. CAS No. 2378808-45-6. Molecular formula: C14H23F3N6O8. Mole weight: 460.36. | |
| Arg-Gly-Glu-Ser | Arg-Gly-Glu-Ser, a RGD-related peptide, is a control for the RGDS ihibitory activity on fibrinogen binding to activated platelets. Synonyms: H-Arg-Gly-Glu-Ser-OH; L-arginyl-glycyl-L-alpha-glutamyl-L-serine; (4S) -4-[[2-[[ (2S) -2-amino-5- (diaminomethylideneamino) pentanoyl]amino]acetyl]amino]-5-[[ (1S) -1-carboxy-2-hydroxyethyl]amino]-5-oxopentanoic acid; RGES. Molecular formula: C16H29N7O8. Mole weight: 447.45. | |
| (-)-cis-3-Aminocyclopentanecarboxylic acid | (-)-(1R,3S)-3-Aminocyclopentanecarboxylic acid is used in the synthesis of aminocyclopentanecarboxylic acid-containing cyclic RGD peptides. It is also used to prepare BMS-457, a potent and selective CCR1 antagonist. Synonyms: (-)-(1R,3S)-3-Aminocyclopentanecarboxylic acid; Cyclopentanecarboxylic acid, 3-amino-, (1R,3S)-; (1R,3S)-3-Aminocyclopentanecarboxylic acid; Cyclopentanecarboxylic acid, 3-amino-, (1R-cis)-; (1R,3S)-3-Aminocyclopentanecarboxylic acid. Grades: ≥95%. CAS No. 71830-08-5. Molecular formula: C6H11NO2. Mole weight: 129.16. | |
| Cyclo(-Arg-Ala-Asp-D-Phe-Cys) | Cyclo(-Arg-Ala-Asp-D-Phe-Cys) is a control peptide for the αvβ3 integrin binding cyclic RGD peptide c(RGDfC). Synonyms: c(RADfC); Cyclo(L-alanyl-L-α-aspartyl-D-phenylalanyl-L-cysteinyl-L-arginyl). Grades: ≥95%. CAS No. 1055991-02-0. Molecular formula: C25H36N8O7S. Mole weight: 592.68. | |
| Cyclo(-Arg-Ala-Asp-D-Tyr-Lys) | Cyclo(-Arg-Ala-Asp-D-Tyr-Lys) is a control peptide for c(RGDyK). Synonyms: c(RADyK); cyclo[L-alanyl-L-alpha-aspartyl-D-tyrosyl-L-lysyl-L-arginyl]; Cyclo(L-alanyl-L-α-aspartyl-D-tyrosyl-L-lysyl-L-arginyl). Grades: ≥95%. CAS No. 1193347-53-3. Molecular formula: C28H43N9O8. Mole weight: 633.71. | |
| Cyclo(-Arg-Gly-Asp-D-Phe-Glu) | Cyclo(-Arg-Gly-Asp-D-Phe-Glu), a cyclic RGD peptide, has been used as an integrin ligand for radiologic labeling, on gold nanoparticles and for the delivery of nanomedicine. Its negative control c(RADfE) is also available. Synonyms: cyclo[L-arginyl-glycyl-L-alpha-aspartyl-D-phenylalanyl-L-alpha-glutamyl]; c(RGDfE); Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-α-glutamyl). Grades: ≥95%. CAS No. 756500-22-8. Molecular formula: C26H36N8O9. Mole weight: 604.62. | |
| Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA | Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) (Cyclo(RGDfV) (TFA))is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) can be used for the research of acute myeloid leukemia [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Cyclo(RGDfV) TFA; C(RGDfV) TFA. CAS No. 199807-33-5. Pack Sizes: 5 mg. Product ID: HY-P1613A. | |
| Cyclo(-Arg-Gly-Asp-D-Tyr-ε-azido-Nle) | Cyclo(-Arg-Gly-Asp-D-Tyr-ε-azido-Nle), an azido derivative of cRGDyK, can be modified or linked to carriers by click chemistry. Synonyms: Azido-c(RGDyK); Cyclo(L-arginylglycyl-L-α-aspartyl-D-tyrosyl-6-azido-L-norleucyl); cyclo[Arg-Gly-Asp-D-Tyr-Nle(N3)]. Grades: ≥95%. CAS No. 1392269-21-4. Molecular formula: C27H39N11O8. Mole weight: 645.68. | |
| Cyclo(-Arg-Gly-Asp-D-Tyr-Lys(Tide FluorTM 7WS)) | Cyclo(-Arg-Gly-Asp-D-Tyr-Lys(Tide FluorTM 7WS)) is a cyclic RGD peptide labeled with a fluorophore absorbing at 749 nm and emitting at 775 nm. Synonyms: c[RGDyK(Tide FluorTM 7WS)]. Grades: ≥90%. Molecular formula: C27H41N9O8 + dye. Mole weight: 1378. | |
| Cyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH) sulfoxide | Cyclo(-D-Tyr-Arg-Gly-Asp-Cys(carboxymethyl)-OH) sulfoxide is a biochemical that has been shown to have a dose-dependent complete inhibition of arterial and venous thrombosis. Synonyms: G 4120; G-4120; Cyclo-S-Ac-tyr-rgd-cys-OH (sulfoxide); L-Cysteine, N-(mercaptoacetyl)-D-tyrosyl-L-arginylglycyl-L-alpha-aspartyl-, cyclic (1-5)-disulfide, S-oxide. Grades: 95%. CAS No. 143120-27-8. Molecular formula: C26H36N8O11S. Mole weight: 668.68. | |
| Cyclo(-Gly-Arg-Gly-Asp-Ser-Pro) | Cyclo(-Gly-Arg-Gly-Asp-Ser-Pro), a cyclic RGD peptide, stimulates the contraction of rat afferent arterioles and is used for targeted delivery of cisplatin. It inhibits the adhesion of mouse B16 melanoma cells to fibronectin coated wells. Synonyms: cyclo[L-arginyl-glycyl-L-alpha-aspartyl-L-seryl-L-prolyl-glycyl]; c(GRGDSP). Grades: ≥90%. CAS No. 135432-37-0. Molecular formula: C22H35N9O9. Mole weight: 569.58. | |
| Cyclo(RADfK) | Cyclo(RADfK) is a selective α(V)β(3) integrin ligand. It has been used for research, therapy, and diagnosis of neoangiogenesis. It is also used as a negative control for the cyclo (-RGDfK-), the RGD peptide, which are modulators of cell adhesion and are recognized by several members of the integrin family. It has low affinity binding to integrin peptides. Uses: Cyclo(radfk) has been used for research, therapy, and diagnosis of neoangiogenesis. it is also used as a negative control for the cyclo (-rgdfk-), the rgd peptide. Synonyms: c(RADfK); cyclo[L-alanyl-L-alpha-aspartyl-D-phenylalanyl-L-lysyl-L-arginyl]. Grades: ≥95%. CAS No. 756500-23-9. Molecular formula: C28H43N9O7. Mole weight: 617.70. | |
| Fluciclatide F-18 | Fluciclatide-F18 is a radiopharmaceutical compound of a small synthetic cyclic peptide containing an RGD-sequence (Arg-Gly-Asp) labeled with the positron-emitting isotope fluorine F 18 that may be used to selectively image tumor cells and tumor vasculature by PET imaging. The RGD motif of fluciclatide F 18 selectively binds to the alphaVbeta3 integrin receptor, commonly upregulated on the surfaces of tumor cells and endothelial cells of tumor vasculature. This agent may be of use in visualizing and quantifying the development of tumor vascularity in response to antiangiogenic agents. Synonyms: [18F]AH111585; 18F-Fluciclatide; Fluciclatide (f-18). CAS No. 879894-01-6. Molecular formula: C75H115FN18O27S3. Mole weight: 1815.02. | |
| GLPG-0187 | GLPG-0187 is a small molecule integrin receptor antagonist (IRA) with nanomolar affinity for the RGD-integrin receptors αvβ1, αvβ3, αvβ5, αvβ6 and α5β1 (IC50s = 1.2-3.7 nM). Integrin receptors are expressed on the surface of tumor vessel endothelial cells and some types of cancer cells, and play a crucial role in endothelial cell adhesion and migration. This compound shows an inhibitory activity of angiogenesis, bone-resorption and tumor, which is hopefully used as an anticancer drug. Uses: An integrin receptor antagonist (ira) can be used as an anticancer drug. Synonyms: GLPG0187; GLPG 0187; GLPG-0187; UNII-43A5P87Z4T; 43A5P87Z4T; SCHEMBL2372722; CHEMBL3319236; (2S) -3-[[2, 5-dimethyl-6-[4- (5, 6, 7, 8-tetrahydro-1, 8-naphthyridin-2-yl) piperidin-1-yl]pyrimidin-4-yl]amino]-2-[ (4-methoxyphenyl) sulfonylamino]propanoic acid. Grades: ≥98 %. CAS No. 1320346-97-1. Molecular formula: C29H37N7O5S. Mole weight: 595.719. | |
| H-Arg-Gly-Asp-Cys-OH | H-Arg-Gly-Asp-Cys-OH, a fibronectin binding motif to cell adhesion molecules, inhibits platelet aggregation and fibrinogen binding. Synonyms: RGDC; H-RGDC-OH; L-arginyl-glycyl-L-alpha-aspartyl-L-cysteine; (6S,12S,15R)-1,6-diamino-12-(carboxymethyl)-1-imino-15-(mercaptomethyl)-7,10,13-trioxo-2,8,11,14-tetraazahexadecan-16-oic acid. Grades: 95%. CAS No. 109292-46-8. Molecular formula: C15H27N7O7S. Mole weight: 449.48. | |
| H-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro-OH | H-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-Pro-OH, an RGD peptide, inhibits the adhesion of fibronectin to fibroblasts. Synonyms: R-G-D-S-P-A-S-S-K-P; L-arginyl-glycyl-L-alpha-aspartyl-L-seryl-L-prolyl-L-alanyl-L-seryl-L-seryl-L-lysyl-L-proline; N5-(Diaminomethylene)-L-ornithylglycyl-L-α-aspartyl-L-seryl-L-prolyl-L-alanyl-L-seryl-L-seryl-L-lysyl-L-proline. Grades: 95%. CAS No. 91575-25-6. Molecular formula: C40H68N14O16. Mole weight: 1001.05. | |
| H-Arg-Gly-Asp-Ser-Pro-OH | H-Arg-Gly-Asp-Ser-Pro-OH is an RGD peptide used to improve the biocompatibility of titanium dental implant model surfaces. It modified to enhance the cell viability in PEG-based hydrogels. Synonyms: H-RGDSP-OH; L-arginyl-glycyl-L-alpha-aspartyl-L-seryl-L-proline. Grades: ≥95%. CAS No. 110697-44-4. Molecular formula: C20H34N8O9. Mole weight: 530.53. | |
| H-Arg-Gly-Glu-Ser-OH | H-Arg-Gly-Glu-Ser-OH is a RGD-related peptide, which is a control of RGDS to inhibit the binding activity of fibrinogen and activated platelet. Synonyms: RGES; H-RGES-OH; L-arginyl-glycyl-L-alpha-glutamyl-L-serine; L-Serine, N-(N-(N-L-arginylglycyl)-L-alpha-glutamyl)-; rgespeptide. Grades: 95%. CAS No. 93674-97-6. Molecular formula: C16H29N7O8. Mole weight: 447.44. | |
| H-Arg-Gly-Glu-Ser-OH.TFA | H-Arg-Gly-Glu-Ser-OH.TFA is a RGD-related peptide, which is a control of RGDS to inhibit the binding activity of fibrinogen and activated platelet. Synonyms: RGES.TFA; H-RGES-OH.TFA; L-arginyl-glycyl-L-alpha-glutamyl-L-serine trifluoroacetic acid. Grades: >98%. Molecular formula: C16H29N7O8.C2HF3O2. Mole weight: 561.47. | |
| H-Glu[cyclo(-Arg-Gly-Asp-D-Phe-Lys)]-cyclo(-Arg-Gly-Asp-D-Phe-Lys) | H-Glu[cyclo(-Arg-Gly-Asp-D-Phe-Lys)]-cyclo(-Arg-Gly-Asp-D-Phe-Lys) is the dimeric form of c(RGDfK), which has better tumor-targeting properties than the monomer. It binds readily to dyes, drug molecules, or chelators. The 68Ga complex of DOTA-E(c(RGDfK))2 has been evaluated as a therapeutic radiopharmaceutical. Synonyms: Cyclo[D-Phe-N6-[N5-[3-[[cyclo(L-Ala-L-Arg-Gly-L-Asp-D-Phe-)]-3-yl]propyl]-L-Gln-]-L-Lys-L-Arg-Gly-L-Asp-]; E(c(RGDfK))2; SU 016. Grades: ≥95%. CAS No. 250612-47-6. Molecular formula: C59H87N19O16. Mole weight: 1318.44. | |
| Integrin alpha-v-beta3 Antagonist, P11 (HSDVHK, HSDVHK-NH2) | A cell-permeable, hexapeptide containing a novel integrin-binding motif, SDV (a Type I PDZ-binding motif) that is shown to compete with vitronectin for the RGD-binding site of integrin avb3 (IC50=1.74pg/ml), in a chip-based assay. It is rapidly internalized into HUVECs, but not in NIH 3T3 cells, at a culture temperature of 37°C, a process which is mediated by caveolin and clathrin. At 10u/ml, this compound is shown to significantly inhibit the phosphorylation of ERK1/2 and MEK in HUVECs. Furthermore, it suppresses bFGF-induced proliferation of HUVECs, dose-dependently, and displays up-regulation of p53 and induction of apoptosis via activation of caspases-3, -8 and -9 at 50ug/ml. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Integrin Antagonist 1 hydrochloride | Integrin Antagonist 1 hydrochloride, a naphthyridine derivative, is a small molecule antagonist of integrin αvβ6. Synonyms: RGD-mimetic-1; 1-Pyrrolidinebutanoic acid, β-[3-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl]-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]-, (βS,3R)- (hydrochloride). CAS No. 1629249-40-6. Molecular formula: C29H38ClN5O2. Mole weight: 524.10. | |
| Integrin Binding Peptide | Integrin Binding Peptide is a peptide containing the cell adhesion sequence RGDSP, which is easily conjugated to carriers via Npys or maleimide chemistry. Synonyms: Ac-Gly-Cys-Gly-Tyr-Gly-Arg-Gly-Asp-Ser-Pro-Gly-NH2; N-acetyl-glycyl-L-cysteinyl-glycyl-L-tyrosyl-glycyl-L-arginyl-glycyl-L-alpha-aspartyl-L-seryl-L-prolyl-glycinamide; Glycinamide, N-acetylglycyl-L-cysteinylglycyl-L-tyrosylglycyl-L-arginylglycyl-L-α-aspartyl-L-seryl-L-prolyl-. Grades: ≥95%. CAS No. 278792-07-7. Molecular formula: C42H63N15O16S. Mole weight: 1066.12. | |
| L-Valine,l-arginylglycyl-L-a-aspartyl- | L-Valine,l-arginylglycyl-L-a-aspartyl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RGDV;ARG-GLY-ASP-VAL;H-ARG-GLY-ASP-VAL-OH;arginyl-glycyl-aspartyl-valine. Product Category: Heterocyclic Organic Compound. CAS No. 93674-99-8. Molecular formula: C17H31N7O7. Mole weight: 445.47. Product ID: ACM93674998. Alfa Chemistry ISO 9001:2015 Certified. |  |
| SF1126 | SF1126 is a water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibitor LY294002/SF1101 conjugated to the RGD-containing tetra-peptide SF1174 with potential antineoplastic and antiangiogenic activities. The targeting peptide SF1174 moiety of pan-PI3K/mTOR inhibitor SF1126 selectively binds to cell surface integrins and, upon cell entry, the agent is hydrolyzed to the active drug SF1101; SF1101 selectively inhibits all isoforms of phosphoinositide-3-kinase (PI3K) and other members of the PI3K superfamily, such as the mammalian target of rapamycin (mTOR) and DNA-PK. By inhibiting the PI3K signaling pathway, this agent may inhibit tumor cell and tumor endothelial cell proliferation and survival. Integrins are transmembrane cell adhesion proteins expressed on the surfaces of endothelial and tumor cells. Synonyms: SF 1126, SF-1126. CAS No. 936487-67-1. Molecular formula: C39H48N8O14. Mole weight: 852.84. | |
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