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Rheumatoid Factor, Control Serum, Human Rheumatoid arthritis (RA) is a chronic inflammatory disease of unknown etiology. Rheumatoid arthritis is a systemic disease characterized by chronic proliferation and inflammation of joint cartilage and supporting structures. RA is mainly defined by clinical criteria, in which systematic pathogenetic studies have been hampered by doubts about the presence of common pathogenetic mechanisms and the relative lack of unique laboratory findings. IgG rheumatoid factor has been reported to be present in sera of patients with rheumatoid arthritis both with and without IgM rheumatoid factor activity. Group: Biologicals. Grades: Serum. Pack Sizes: 2ml. US Biological Life Sciences. USBiological 1
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10-Hydroxy Aconitine 10-Hydroxy Aconitine is a toxic constituent from aconitum plants and known for its effects against rheumatism and rheumatoid arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 41849-35-8. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C34H47NO12, Molecular Weight: 661.74. US Biological Life Sciences. USBiological 9
Worldwide
(11 β,16 β)-11,21-bis(acetyloxy)-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione. (Deflazacort Impurity) (11 β,16 β)-11,21-bis(acetyloxy)-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, is an impurity of Deflazacort, which is a systemic corticosteroid, used for rheumatoid arthritis and lupus. Group: Biochemicals. Grades: Highly Purified. CAS No. 710951-92-1. Pack Sizes: 10mg, 100mg. Molecular Formula: C27H33NO7, Molecular Weight: 483.55. US Biological Life Sciences. USBiological 9
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11-Deoxy Corticosterone Pivalate 11-Deoxycorticosterone Pivalate is a mineralocorticoid hormone and an analog of desoxycorticosterone. 11-Deoxycorticosterone Pivalate is used in the treatment of adrenocortical insufficiency. It is used to treat in patients suffering from rheumatoid arthritis. Group: Biochemicals. Alternative Names: 21-(2,2-dimethyl-1-oxopropoxy)pregn-4-ene-3,20-dione; 11-Deoxycorticosterone Pivalate; 21-Hydroxypregn-4-ene-3,20-dione pivalate; Cortexone M; DOCP; DTMA; Deoxycorticosterone Trimethylacetate; Deoxycortone Pivalate; Deoxycortone Trimethylacetate; Desoxycorticosterone Pivalate; Desoxycortisone pivalate; Desoxycortone pivalate; NSC 95278; Neodin-Depositum; Percorten M; Percorten Pivalate. Grades: Highly Purified. CAS No. 808-48-0. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
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11-epi Deflazacort 11-epi Deflazacort is an isomer of Defazacort (D229875), which is a systemic corticosteroid and derivative of prednisolone. Deflazacort is used for rheumatoid arthritis and lupus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2mg. Molecular Formula: C25H31NO6, Molecular Weight: 441.52. US Biological Life Sciences. USBiological 9
Worldwide
11-epi Deflazacort 11-epi Deflazacort is an isomer of Deflazacort, which is a systemic corticosteroid used to treat rheumatoid arthritis and lupus. Synonyms: 2-((6aR,6bS,7R,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-6a,8a,10-trimethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d]oxazol-8b-yl)-2-oxoethyl acetate; (11α,16β)-21-(Acetyloxy)-11-hydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione. Molecular formula: C25H31NO6. Mole weight: 441.52. BOC Sciences 8
1,2,3,4,5,6-Hexa-O-acetyl-myo-inositol 1,2,3,4,5,6-Hexa-O-acetyl-myo-inositol is a valuable compound widely used in biomedicine. With its anti-inflammatory properties, it plays a crucial role in the research of various diseases such as rheumatoid arthritis, Crohn's disease, and inflammatory bowel disease. Additionally, this product is utilized in the synthesis of novel drugs targeting inflammatory pathways, making it an essential component in biomedical research and drug development. Synonyms: myo-Inositol Hexaacetate; Myo-inositol, hexaacetate; (2,3,4,5,6-pentaacetyloxycyclohexyl) acetate; 1,2,3,4,5,6-Hexa-O-acetyl-myo-inositol; myo-Inositol, 1,2,3,4,5,6-hexaacetate; 18779-57-2; Cyclohexane-1,2,3,4,5,6-hexayl hexaacetate; 1-O,2-O,3-O,4-O,5-O,6-O-Hexaacetyl-muco-inositol; Myoinositol hexaacetate; (1R,2R,3S,4R,5s,6S)-cyclohexane-1,2,3,4,5,6-hexayl hexaacetate; 1-Hoami; Mesoinositol hexaacetate; neo-Inositol hexaacetate; Inositol, hexaacetate, myo-; Hexakis-O-acetyl-myo-inositol; inositol hexaacetate; 1,2,3,4,5,6-Hexaacetylinositol1111. CAS No. 1254-38-2. Molecular formula: C18H24O12. Mole weight: 432.16. BOC Sciences 11
1,2,3,4-Tetra-O-pivaloyl-b-D-glucuronide methyl ester Inhibiting the activity of the enzymes crucial to the inflammation process, 1,2,3,4-Tetra-O-pivaloyl-b-D-glucuronide methyl ester serves as a crucial drug in treating inflammatory diseases like rheumatoid arthritis. Its therapeutic effect involves regulating the immune system by modulating the activity of immune cells, thus curtailing the release of cytokines responsible for inflammation. In addition, its anti-inflammatory action extends beyond suppressing cytokine levels, owing to its ability to halt inflammation cascade reactions with marked efficacy, thereby making it a reliable remedy for patients suffering from inflammatory diseases. Synonyms: Methyl 1,2,3,4-tetra-O-pivaloyl-beta-D-glucopyranosyluronate. CAS No. 86448-91-1. Molecular formula: C27H44O11. Mole weight: 544.63. BOC Sciences 11
1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one 1-(2-C-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one, a remarkably potent compound extensively employed in the biomedical sector, showcases substantial properties pertaining to inflammation reduction and immune system modulation. Notably, this product finds its primary application in the advancement of innovative pharmaceuticals targeting renowned autoimmune disorders such as rheumatoid arthritis and multiple sclerosis. Synonyms: 1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-5-nitropyridin-2(1H)-one. Molecular formula: C11H14N2O7. Mole weight: 286.24. BOC Sciences 3
1,3,4,6-Tetra-O-acetyl-b-D-glucosamine HCl 1,3,4,6-Tetra-O-acetyl-b-D-glucosamine HCl - a chemical compound known for its numerous therapeutic applications, including the development of drugs for osteoarthritis, rheumatoid arthritis, and autoimmune diseases. Of particular interest is its use in biomedicine, where it has proven invaluable in the preparation of glycan arrays - crucial tools for the study of glycobiology and drug discovery. Its multifaceted properties make it a promising candidate for further research and exploration. Synonyms: 1,3,4,6-Tetra-O-acetyl-2-amino-2-deoxy-b-D-glucopyranose HCl. CAS No. 10034-20-5. Molecular formula: C14H21NO9.HCl. Mole weight: 383.78. BOC Sciences 12
(16 β)-21-(Acetyloxy)-2'-methyl-5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,11,20-trione (16 β)-21-(Acetyloxy)-2'-methyl-5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,11,20-trione, is an impurity of Deflazacort (D228975), a systemic corticosteroid, and a derivative of prednisolone. Used for rheumatoid arthritis and lupus. Group: Biochemicals. Grades: Highly Purified. CAS No. 13649-84-8. Pack Sizes: 100mg, 500mg. Molecular Formula: C25H29NO6. US Biological Life Sciences. USBiological 9
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1,6-Diacetyl 3,4-Dideoxyglucosone-3-ene An intermediate for immunosuppressants useful for chronic rheumatoid arthritis and autoimmune disease treatment. Synonyms: 2-(Acetyloxy)-6-[(acetyloxy)methyl]-2H-pyran-3(6H)-one; 1,6-Diacetyl 3,4-DGE. CAS No. 1391048-02-4. Molecular formula: C10H12O6. Mole weight: 228.2. BOC Sciences 12
1-Benzyl-4-methyl-3-(methylamino)piperidine Dihydrochloride A dihydrochloride salt form of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: N,4-dimethyl-1-(phenylmethyl)-3-piperidinamine;dihydrochloride; 1-benzyl-N,4-dimethylpiperidin-3-amine;dihydrochloride. Grades: 99 %. CAS No. 1228879-37-5. Molecular formula: C14H24Cl2N2. Mole weight: 291.26. BOC Sciences 7
(1R,3S)-3-Aminocyclopentanol Hydrochloride (1R,3S)-3-Aminocyclopentanol Hydrochloride is used to for the preparation of 6-Aminopyridin-3-ylthiazoles as a method of treating or ameliorating a syndrome, disorder or disease related rheumatoid arthritis or psoriasis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1279032-31-3. Pack Sizes: 25mg, 50mg. Molecular Formula: C5H12ClNO, Molecular Weight: 137.61. US Biological Life Sciences. USBiological 9
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(1R,3S,4R,5S)-1,3,4-trihydroxy-5-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy-cyclohexane-1-carboxylic acid (1R,3S,4R,5S)-1,3,4-trihydroxy-5-[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]oxy-cyclohexane-1-carboxylic acid - an anti-inflammatory compound - exhibits efficacy in the reduction of inflammation, as well as the alleviation of pain and swelling commonly observed in Rheumatoid Arthritis, Osteoarthritis, and other inflammatory diseases. Endowed with multiple therapeutic benefits, this drug is a preferred choice prescribed by medical professionals to ensure the complete restoration of patients' health and well-being. CAS No. 5746-55-4. Molecular formula: C16H18O8. Mole weight: 338.10. BOC Sciences 9
1-Thio- β-D-glucose-13C6 Sodium Salt 1-Thio- β-D-glucose-13C6 Sodium Salt is an intermediate in synthesizing Aurothioglucose-13C6 (A794792), a labelled analogue of Aurothioglucose (A794790), which is used in the treatment of rheumatoid arthritis and psoriasis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 25mg. Molecular Formula: 13C6H11NaO5S, Molecular Weight: 224.16. US Biological Life Sciences. USBiological 9
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21-Desacetyl 21-Formyl Deflazacort 21-Desacetyl 21-Formyl Deflazacort is a derivative of Deflazacort (D228975) which is a systemic corticosteroid used for rheumatoid arthritis and lupus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C24H29NO6, Molecular Weight: 427.49. US Biological Life Sciences. USBiological 10
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21-Desacetyl 21-O-Iodometyl Deflazacort 21-Desacetyl 21-O-Iodometyl Deflazacort is an impurity of Deflazacort (D228975) which is a systemic corticosteroid and derivative of prednisolone. Deflazacort is used for rheumatoid arthritis and lupus. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H28INO5, Molecular Weight: 525.38. US Biological Life Sciences. USBiological 10
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21-Desacetyl 21-O-Iodometyl Deflazacort 21-Desacetyl 21-O-Iodometyl Deflazacort is an impurity of Deflazacort, which is a systemic corticosteroid used to treat rheumatoid arthritis and lupus. Synonyms: 2-((6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-6a,8a,10-trimethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d]oxazol-8b-yl)-2-oxoethyl hypoiodite. Grades: 99%. Molecular formula: C23H28INO5. Mole weight: 525.38. BOC Sciences 8
21-Desacetyl Deflazacort A metabolite of Deflazacort, a systemic corticosteroid, a derivative of prednisolone and used for rheumatoid arthritis and lupus. Synonyms: 5'H-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, 11,21-dihydroxy-2'-methyl-, (11β,16β)-; (11β,16β)-11,21-Dihydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-dione; Deacetyldeflazacort; Deflazacortalcohol; 21-Deacetyldeflazacort; 5'βH-Pregna-1,4-dieno[17,16-d]oxazole-3,20-dione, 11β,21-dihydroxy-2'-methyl-; L 6485. Grades: ≥95%. CAS No. 13649-57-5. Molecular formula: C23H29NO5. Mole weight: 399.48. BOC Sciences 8
21-Desacetyl Deflazacort-d3 (Major) A labeled metabolite of Deflazacort a systemic corticosteroid, a derivative of Prednisolone and used for rheumatoid arthritis and lupus. Group: Biochemicals. Alternative Names: (11 β,16 β)-11,21-Dihydroxy-2'-methyl-5'H-pregna-1,4-dieno[17,16-d]oxazole-3,20-di-one-d3; Deacetyldeflazacort-d3; Deflazacortalcohol-d5; L 6485-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
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2- (1- (Ethylsulfonyl) azetidin-3-ylidene) acetonitrile 2- (1- (Ethylsulfonyl) azetidin-3-ylidene) acetonitrile is an intermediate in the synthesis of Baricitinib, a JAK 1 and 2 inhibitor used in the treatment of rheumatoid arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1187595-85-2. Pack Sizes: 1g, 5g. Molecular Formula: C7H10N2O2S, Molecular Weight: 186.23. US Biological Life Sciences. USBiological 9
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2,3,4,6-Tetra-O-acetyl- β-D-glucopyranosyl Ethylxanthate-13C6 2,3,4,6-Tetra-O-acetyl- β-D-glucopyranosyl Ethylxanthate-13C6 is an intermediate in synthesizing Aurothioglucose-13C6 (A794792), a labelled analogue of Aurothioglucose (A794790), which is used in the treatment of rheumatoid arthritis and psoriasis. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 50mg. Molecular Formula: C1113C6H24O10S2, Molecular Weight: 458.45. US Biological Life Sciences. USBiological 10
Worldwide
2,5-Deoxyfructosazine 2,5-Deoxyfructosazine, a biomedical compound, exhibits significant therapeutic potential in the management of chronic inflammatory diseases. Through its inhibitory mechanism targeting pro-inflammatory molecules, it effectively mitigates inflammation associated with conditions including rheumatoid arthritis and inflammatory bowel disease. This extraordinary bioactive substance acts as an immunomodulator, imparting profound relief and substantially enhancing the overall well-being of afflicted patients. Synonyms: (1R,2S,3R)-1-[5-[(2S,3R)-2,3,4-Trihydroxybutyl]-2-pyrazinyl]-1,2,3,4-butanetetrol 2-(D-arabino-tetrahydroxybutyl)-5-(D-erythro-2,3,4-trihydroxybutyl)pyrazine NSC 270912. CAS No. 17460-13-8. Molecular formula: C12H20N2O7. Mole weight: 304.30. BOC Sciences 12
2-Acetamido-2-deoxy-3-O-(b-D-gluco-4-enepyranosyl uronic acid)-6-sulfo-D-galactopyranose disodium salt 2-Acetamido-2-deoxy-3-O-(b-D-gluco-4-enepyranosyl uronic acid)-6-sulfo-D-galactopyranose disodium salt, commonly known as AMPAGUS, is a multifaceted pharmaceutical entity meticulously designed to study a wide spectrum of inflammatory ailments plaguing humanity, including the formidable rheumatoid arthritis and the insidious Crohn's disease. With its remarkable intervention abilities, AMPAGUS efficaciously regulates and subdues vital enzymatic cascades orchestrating the arduous inflammatory response. Molecular formula: C14H19NO14S.2Na. Mole weight: 503.34. BOC Sciences 12
2-Amino-5,6-dimethoxypyridine 2-Amino-5,6-dimethoxypyridine is used in the design of Spleen Tyrosine Kinase (Syk) inhibitors used in the treatment of autoimmune diseases such as asthma, rheumatoid arthitis and SLE. Group: Biochemicals. Grades: Highly Purified. CAS No. 127980-46-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C7H10N2O2, Molecular Weight: 154.169999999999. US Biological Life Sciences. USBiological 9
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2-Aminomethyl-3-chloropyrazine 2-Aminomethyl-3-chloropyrazine is used in the discovery of 8-Amino-imidazo[1,5-a]pyrazine-based Bruton’s tyrosine kinase (BTK) inhibitors for treating rheumatoid arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 771581-15-8. Pack Sizes: 50mg, 250mg. Molecular Formula: C5H6ClN3, Molecular Weight: 143.57. US Biological Life Sciences. USBiological 10
Worldwide
2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide 2-Cyano-3-hydroxy-N-(4-methylphenyl)-2-butenamide is an impurity of Teriflunomide (A771726) which is the active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. Group: Biochemicals. Grades: Highly Purified. CAS No. 1385789-70-7. Pack Sizes: 10mg, 25mg. Molecular Formula: C12H12N2O2, Molecular Weight: 216.24. US Biological Life Sciences. USBiological 10
Worldwide
2-Cyanoadenosine 2-Cyanoadenosine is a biomedical compound used in the treatment of autoimmune diseases and chronic inflammatory conditions. It exhibits immunosuppressive effects by modulating the immune response. PubMed studies suggest its potential in managing rheumatoid arthritis, lupus erythematosus, and multiple sclerosis. Synonyms: Adenosine, 2-cyano-; 6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purine-2-carbonitrile. Grades: ≥95%. CAS No. 79936-11-1. Molecular formula: C11H12N6O4. Mole weight: 292.25. BOC Sciences 3
2'-Deoxy-2'-fluoro-4'-thio-b-D-arabinouridine 2'-Deoxy-2'-fluoro-4'-thio-b-D-arabinouridine, a robust medication utilized in the treatment of various cancers spanning from pancreatic, breast, to colon cancer, ameliorates the condition by hindering DNA synthesis through the suppression of the enzyme ribonucleotide reductase. Furthermore, its multifaceted properties suggest it as an attractive immunosuppressant for tackling autoimmune diseases such as rheumatoid arthritis or multiple sclerosis. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-4-thio-β-D-arabinofuranosyl)-; 2'-Deoxy-2'-fluoro-4'-thio-β-D-arabinouridine; 1-[(2R,3S,4S,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]pyrimidine-2,4-dione; 1-(2-Deoxy-2-fluoro-4-thio-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 941610-00-0. Molecular formula: C9H11FN2O4S. Mole weight: 262.26. BOC Sciences 2
2'-Deoxyinosine 5'-monophosphate 2'-Deoxyinosine 5'-monophosphate, a vital biomolecule, intricately participates in the synthesis of DNA. With its involvement in the regulation of DNA replication and repair through the nucleotide dITP, this compound paves the way towards improved treatment processes. Notably, this biomolecule is also utilized in the management of autoimmune disorders inclusive of lupus and rheumatoid arthritis. Synonyms: Deoxyinosine monophosphate; 2''-Deoxyinosine-5''-monophosphoric acid; 2'-Deoxy-5'-inosinic acid; 2'-Deoxy-IMP; Hypoxanthine deoxyriboside; 9-(2-deoxy-5-O-phosphono-beta-D-erythro-pentofuranosyl)-9H-purin-6-ol. Grades: ≥98% by HPLC. CAS No. 3393-18-8. Molecular formula: C10H13N4O7P. Mole weight: 332.21. BOC Sciences 2
(2R,3R,3aS,9aR)-2,3,3a,9a-Tetrahydro-3-hydroxy-2-(hydroxymethyl)-3a-methyl-6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one (2R,3R,3aS,9aR)-2,3,3a,9a-Tetrahydro-3-hydroxy-2-(hydroxymethyl)-3a-methyl-6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one is a potent biomedicine used in the treatment of various diseases. Its unique chemical structure allows it to target specific receptors involved in inflammatory responses, making it highly effective against autoimmune disorders such as rheumatoid arthritis and multiple sclerosis. Extensive research has shown promising results in inhibiting the overactivation of immune cells, thereby reducing inflammation associated with these conditions. Molecular formula: C10H12N2O5. Mole weight: 240.22. BOC Sciences 12
(2R,3S,4R,5S)-3,4-Dihydroxy-3,4-O-isopropylidene-2,5-bis-[(tert-butyldimethylsilyloxy)methyl]-1-benzyl-2-pyrrolidine (2R,3S,4R,5S)-3,4-Dihydroxy-3,4-O-isopropylidene-2,5-bis-[(tert-butyldimethylsilyloxy)methyl]-1-benzyl-2-pyrrolidine, a scientifically significant pharmaceutical compound, emerges as a pivotal agent in the treatment of a multitude of ailments. Its prominent role in the biomedical industry revolves around exerting potent anti-inflammatory effects, with a primary focus on alleviating autoimmune disorders like rheumatoid arthritis and multiple sclerosis. By adeptly suppressing the production of pro-inflammatory molecules, this unparalleled compound offers respite to afflicted patients grappling with these debilitating conditions. BOC Sciences 12
3,2',3',4'-Tetra-O-acetyl-6,6'-di-O-triisopropylsilyl-lactal 3,2',3',4'-Tetra-O-acetyl-6,6'-di-O-triisopropylsilyl-lactal possesses critical significance within the biomedical sector as it serves as a pivotal intermediary component during the creation of prospective anti-inflammatory medications. Its utilization facilitates the innovation of groundbreaking therapeutic solutions targeting prevalent inflammatory conditions like rheumatoid arthritis and asthma. This compound showcases remarkable pharmacological attributes and assumes an indispensable role as a foundational element advancing the field of drug exploration and progression within the realm of biomedicine. Molecular formula: C38H68O13Si2. Mole weight: 789.11. BOC Sciences 12
3-((3R,4R)-4-methyl-3-(methylamino)piperidin-1-yl)-3-oxopropanenitrile hydrochloride An impurity of Tofacitinib, a Janus kinase inhibitor that could be used against rheumatoid arthritis. CAS No. 1640971-87-4. Molecular formula: C10H18ClN3O. Mole weight: 231.72. BOC Sciences 8
3'-(6-TAMRA) CPG 1000 3'-(6-TAMRA) CPG 1000 is a specialized product that plays a pivotal role in biomedicine to treat various diseases like cancer, rheumatoid arthritis, and asthma. It is used in research pertaining to the development of vaccines, therapeutic antibodies, and gene therapy extensively. BOC Sciences 3
3-Hydroxymethyl mefenamic acid acyl b-D-glucuronide 3-Hydroxymethyl mefenamic acid acyl b-D-glucuronide, a remarkable biomedicine compound, holds tremendous promise for combating inflammatory pain and fever associated with diverse ailments, including rheumatoid arthritis and osteoarthritis. With its exceptional analgesic and anti-inflammatory properties, it expertly hampers the production of prostaglandins - the instigators of distress and inflammation. Synonyms: 3-Hydroxymethyl Mefenamic Acid Acyl-|A-D-glucuronide; 3-Hydroxymethyl Mefenamic Acid Acyl-beta-D-glucuronide; 3,4,5-trihydroxy-6-[2-[3-(hydroxymethyl)-2-methylanilino]benzoyl]oxyoxane-2-carboxylic acid; FT-0669809. CAS No. 152832-29-6. Molecular formula: C21H23NO9. Mole weight: 433.41. BOC Sciences 12
3-Indoxyl caprylate 3-Indoxyl caprylate, an intriguing compound prevalent in the biomedical sector, has sparked considerable interest due to its potential anti-inflammatory attributes. Its effectiveness in restraining the generation of pro-inflammatory cytokines and mitigating inflammation in diverse ailments, including rheumatoid arthritis and inflammatory bowel disease, has been extensively investigated. This compound exhibits remarkable promise as a therapeutic modality for combating inflammatory conditions, emphasizing its significance within the medical realm. Synonyms: 3-Indoxyl octanoate. CAS No. 133950-66-0. Molecular formula: C16H21NO2. Mole weight: 259.34. BOC Sciences 12
(3R,4R)-1-Benzyl-3-(methylamino)-4-methylpiperidine Dihydrochloride (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride is an impurity of Tofacitinib, a medication used to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Synonyms: (3R,4R)-N,4-dimethyl-1-(phenylmethyl)-3-piperidinamine;dihydrochloride; (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine;dihydrochloride. CAS No. 1062580-52-2. Molecular formula: C14H24Cl2N2. Mole weight: 291.26. BOC Sciences 8
(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine (3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine is an impurity of Tofacitinib, a medication used to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. CAS No. 1638499-31-6. Molecular formula: C14H22N2. Mole weight: 218.34. BOC Sciences 8
(3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine (3S,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine is an impurity of Tofacitinib, a medication used to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Synonyms: (3S,4R)-N,4-Dimethyl-1-(phenylmethyl)-3-piperidinamine. CAS No. 1638499-33-8. Molecular formula: C14H22N2. Mole weight: 218.34. BOC Sciences 8
(3S,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride (3S,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride is an impurity of Tofacitinib, a medication used to treat rheumatoid arthritis, psoriatic arthritis and ulcerative colitis. Synonyms: Tofacitinib impurity G; Tofacitinib Impurity 02; cis-1-Benzyl-3-(methylamino)-4-methylpiperidine dihydrochloride. CAS No. 1354486-07-9. Molecular formula: C14H24Cl2N2. Mole weight: 291.3. BOC Sciences 8
4,6-O-(4-Methoxybenzylidene)-1,2,3-tri-O-pivaloyl-b-D-glucopyranose 4,6-O-(4-Methoxybenzylidene)-1,2,3-tri-O-pivaloyl-b-D-glucopyranose is a versatile compound, exhibiting anti-inflammatory and antioxidant properties, which makes it effective in studying various diseases such as rheumatoid arthritis is asthma is and cancer. Additionally, this compound shows promise in drug delivery systems due to its ability to enhance bioavailability and targeted drug release. Molecular formula: C29H42O10. Mole weight: 550.65. BOC Sciences 11
4,6-O-Benzylidene-1,3-di-O-methyl-a-D-mannopyranoside 4,6-O-Benzylidene-1,3-di-O-methyl-α-D-mannopyranoside is a crucial compound used in the biomedical industry. Known for its anti-inflammatory properties, it has shown promising results in the treatment of various diseases like rheumatoid arthritis and inflammatory bowel disease. This compound acts as a potent inhibitor, targeting specific enzymes involved in inflammatory pathways, thus reducing discomfort and swelling. Synonyms: Methyl 4,6-benzylidene-3-O-methyl-a-D-mannopyranoside. CAS No. 52260-48-7. Molecular formula: C15H20O6. Mole weight: 296.32. BOC Sciences 11
4-Chlorophenyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside 4-Chlorophenyl 2-Acetamido-3,4,6-Tri-O-Acetyl-2-Deoxy-b-D-Glucopyranoside, renowned for its extraordinary anti-inflammatory attributes, consistently garners substantial attention within the biomedical domain. Due to its distinctive chemical makeup and intricate mode of operation, this potent substance plays a vital role in pharmaceutical research and the identification of efficacious therapeutics for a plethora of ailments, such as rheumatoid arthritis, inflammatory bowel disease, and chronic inflammatory conditions. Synonyms: [5-acetamido-3,4-diacetyloxy-6-(4-chlorophenoxy)oxan-2-yl]methyl acetate; F1507-0115; [5-acetamido-3,4-diacetyloxy-6-(4-chloranylphenoxy)oxan-2-yl]methyl ethanoate; 1094814-79-5; [3,4-bis(acetyloxy)-6-(4-chlorophenoxy)-5-acetamidooxan-2-yl]methyl acetate; 4'-Chlorophenyl 2-acetamido-3,4,6-tetra-O-acetyl-2-Deoxy-beta-d-glucopyranoside; DTXSID40393988; AKOS001176751; AKOS016295637; 5-acetamido-2-(acetoxymethyl)-6-(4-chlorophenoxy)tetrahydro-2H-pyran-3,4-diyl diacetate; FT-0658589; A828269; SR-01000908800; SR-01000908800-1; Z55186898; acetic acid [5-acetamido-3,4-diacetyloxy-6-(4-chlorophenoxy)-2-oxanyl]methyl ester. CAS No. 50729-97-0. Molecular formula: C20H24ClNO9. Mole weight: 457.86. BOC Sciences 11
4-epidemeclocycline A Tetracycline analog as gelatinase inhibitor, used for the treatment of diseases such as rheumatoid arthritis and multiple sclerosis. Synonyms: [4R-(4α, 4aβ, 5aβ, 6α, 12aβ)]-7-Chloro-4-(dimethylamino)-1, 4, 4a, 5, 5a, 6, 11, 12a-octahydro-3, 6, 10, 12, 12a-pentahydroxy-1, 11-dioxo-2-naphthacenecarboxamide; 4-Epidemeclocycline. Grades: > 95%. CAS No. 14206-59-8. Molecular formula: C21H21ClN2O8. Mole weight: 464.85. BOC Sciences
4-Methoxyphenylhydrazine hydrochloride 4-Methoxyphenylhydrazine hydrochloride is an intermediate of Indomethacin, which is a non-steroidal anti-inflammatory drug used in the treatment of musculoskeletal and joint disorders, including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis. Synonyms: Hydrazine, (4-methoxyphenyl)-, hydrochloride (1:x); Hydrazine, (4-methoxyphenyl)-, hydrochloride. Grades: ≥95%. CAS No. 70672-74-1. Molecular formula: C7H10N2O.xHCl. Mole weight: 138.17 (free base). BOC Sciences 6
4-Nitrophenyl 3-O-benzoyl-4,6-cyclohexylidene-b-D-mannopyranoside 4-Nitrophenyl 3-O-benzoyl-4,6-cyclohexylidene-b-D-mannopyranoside, a vital chemical compound extensively utilized in the biomedical sector, exudes a distinct essence of academic ingenuity. This multifaceted entity manifests its prowess through its profound anti-inflammatory attributes, thereby serving as a catalyst for groundbreaking pharmaceutical innovations aimed at mitigating chronic inflammatory afflictions like rheumatoid arthritis and inflammatory bowel diseases. Synonyms: 4-Nitrophenyl 4,6-O-cyclohexylidene-b-D-mannopyranoside 3-benzoate. CAS No. 102717-17-9. Molecular formula: C25H27NO9. Mole weight: 485.48. BOC Sciences 12
4-O-(b-D-Glucopyranosyl)-a-D-thioglucopyranose 4-O-(b-D-Glucopyranosyl)-a-D-thioglucopyranose is a compound of significance in compound, exhibiting notable anti-inflammatory attributes and potent antioxidative properties, thereby positioning it as a compelling contender for studying chronic inflammatory phenomena, such as the well-known malady, rheumatoid arthritis. Molecular formula: C12H22O10S. Mole weight: 358.36. BOC Sciences 12
4-Phenylcyclohexanone 4-Phenylcyclohexanone is used in the synthesis of CCR2 antagonists for the treatment of rheumatoid arthritis, atherosclerosis and other disease states. Also used in the preparation of coumarins via dehydrogenation and Heck coupling reactions. Group: Biochemicals. Alternative Names: 4-Phenyl-1-cyclohexanone; 4-Phenylcyclohexanone; NSC 28473. Grades: Highly Purified. CAS No. 4894-75-1. Pack Sizes: 10g. US Biological Life Sciences. USBiological 3
Worldwide
4'-Thioinosine 4'-Thioinosine, a purine nucleoside analog utilized within the biomedical industry to study adenosine transport inhibition's effects on tumor growth. Its potential as a treatment for autoimmune diseases, like rheumatoid arthritis, has been established via the suppression of inflammatory pathways. Synonyms: NSC 90420; 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]-1H-purin-6-one; Inosine, 4'-thio-. Grades: ≥95%. CAS No. 58004-19-6. Molecular formula: C10H12N4O4S. Mole weight: 284.29. BOC Sciences 2
5-Methyl-3,4-diphenyl-4,5-dihydroisoxazol-5-ol An intermediate for the preparation of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Uses: Intermediate for the preparation of valdecoxib. Synonyms: 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol. CAS No. 181696-73-1. Molecular formula: C16H15NO2. Mole weight: 253.30. BOC Sciences 8
5(S)-HETE 5(S)-HETE is an endogenous metabolite present in Blood that can be used for the research of Rheumatoid Arthritis, Rhinitis and Asthma [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 70608-72-9. Pack Sizes: 25 μg (312.04 μM * 250 μL in Ethanol); 50 μg (312.04 μM * 500 μL in Ethanol). Product ID: HY-113434. MedChemExpress MCE
6-a-Fucosyl chitobiose 6-a-Fucosyl chitobiose is a compound used in the research of various diseases playing a crucial role in modulating immune responses and cell adhesion processes. This compound exhibits potent anti-inflammatory properties, making it an effective compound for studying autoimmune disorders such as rheumatoid arthritand multiple sclerosis. Furthermore, it shows promising potential in targeting cancer cells due to its ability to inhibit tumor growth and metastasis. Synonyms: GlcNb1-4{Fuca1-6}GlcN. BOC Sciences 12
6-Chloro-7-deazapurine One of the impurities of Tofacitinib, which is a Janus kinase inhibitor and could be used against rheumatoid arthritis. Synonyms: 4-Chloro-1H-pyrrolo[2,3-d]pyrimidine; 4-Chloropyrrolo[2,3-d]pyrimidine; NSC 64952. Grades: ≥98% by HPLC. CAS No. 3680-69-1. Molecular formula: C6H4ClN3. Mole weight: 153.57. BOC Sciences 7
6-isobutyl-3-methyl-2,3-dihydro-1H-inden-1-one 6-isobutyl-3-methyl-2,3-dihydro-1H-inden-1-one is an impurity of ibuprofen, a racetam derivative with anticonvulsant (anti-epileptic) properties. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) commonly used to relieve pain, reduce fever, and reduce inflammation. It can be used to treat menstrual pain, migraines, and rheumatoid arthritis. Synonyms: 6-Isobutyl-3-methyl-1-indanone. CAS No. 1340024-54-5. Molecular formula: C14H18O. Mole weight: 202.29. BOC Sciences 8
6-keto Prostaglandin F1α 6-keto Prostaglandin F1α is an endogenous metabolite present in Cerebrospinal_Fluid, Urine and Blood that can be used for the research of Meningitis, Rheumatoid Arthritis and Cardiopulmonary Resuscitation [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 58962-34-8. Pack Sizes: 1 mg. Product ID: HY-113358. MedChemExpress MCE
8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate - OYSTER-656 OYSTER-656 is a small molecule compound that acts as an agonist of the P2Y11 receptor. It is used to treat autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease due to its immunomodulatory effects. OYSTER-656 also has potential applications in cancer therapy and dermatological conditions. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate, labeled with OYSTER 656, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H29N7O10P2- OYSTER 656 (free acid). Mole weight: 1258.37 (free acid). BOC Sciences 2
8-Bromo-5'-O-[(4-cyanophenyl)methyl]-2',3'-di-O-(1-methylethylidene)adenosine 8-Bromo-5'-O-[(4-cyanophenyl)methyl]-2',3'-di-O-(1-methylethylidene)adenosine is a remarkable pharmaceutical compound with anti-inflammatory and immunomodulatory attributes. Potential applications include the research of various inflammatory ailments like rheumatoid arthritand asthma. Synonyms: 8-Bromo-5'-O-(4-cyanobenzyl)-2',3'-di-O-isopropylidene adenosine; 4-[[(3aR,4R,6R,6aR)-4-(6-amino-8-bromopurin-9-yl)-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methoxymethyl]benzonitrile; Adenosine, 8-bromo-5'-O-[(4-cyanophenyl)methyl]-2',3'-O-(1-methylethylidene)-. Grades: ≥95%. CAS No. 1134156-53-8. Molecular formula: C21H21BrN6O4. Mole weight: 501.33. BOC Sciences 2
8-Ethoxycarbonylheptyl N,N-di-O-acetyl-b-chitobioside 8-Ethoxycarbonylheptyl N,N-di-O-acetyl-β-chitobioside is a pivotal compound extensively utilized in the biomedical sector, garners attention due to its multifaceted applications. Owing to its distinctive composition, it exhibiting a remarkable capability to selectively target distinctive pathological routes, thus presenting an optimistic avenue for studying afflictions like rheumatoid arthritis is asthma and chronic obstructive pulmonary disease (COPD). Molecular formula: C26H46N2O13. Mole weight: 594.65. BOC Sciences 12
A1F N-Glycan A1F N-Glycan, the versatile biomolecule employed by the biomedical industry, is the key player in the in-depth scrutiny and diagnosis of diverse disorders - think cancer, Alzheimer's, and rheumatoid arthritis. Its multifaceted involvement in cell signaling pathways has made it a go-to diagnostic marker in countless clinical settings. Furthermore, the therapeutic potential of A1F N-Glycan has not gone unexploited; it forms the crux of several drug formulations aimed at combating these afflictions. Synonyms: Monosialo (2,6), fucosylated biantennary (A1F); A1F glycan; FA2G2S1 Glycan; Mono-sialylated, galactosylated, core-fucosylated, bi-antennary N-linked glycan; Mannotriose-(fucosyl-di-[N-acetylglucosamine]), mono-sialyl-bis(galactosyl-N-acetylglucosaminyl); NeuNAc(Gal-GlcNAc)2Man3(GlcNAc)2Fuc. Grades: ≥90%. CAS No. 571188-30-2. Molecular formula: C79H131N5O58. Mole weight: 2078.88. BOC Sciences
A77 1726-d4 (N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide-d4, 2-Cyano-3-hydroxy-N-[4- (trifluoromethyl) phenyl]-2-beuteamide-d4, LEF-M-d4) The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function. Group: Biochemicals. Alternative Names: N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide-d4, 2-Cyano-3-hydroxy-N-[4- (trifluoromethyl) phenyl]-2-beuteamide-d4, LEF-M-d4. Grades: Highly Purified. CAS No. 1185240-22-5. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
A77 1726 (N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4- (trifluoromethyl) phenyl]-2-beuteamide, LEF-M) The active metabolite of Leflunomide, a potent disease-modifying antirheumatic drug used in the treatment of rheumatoid arthritis. LEF-M interferes with dendritic cell function. Group: Biochemicals. Alternative Names: N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4- (trifluoromethyl) phenyl]-2-beuteamide, LEF-M. Grades: Highly Purified. CAS No. 163451-81-8. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 1
Worldwide
A antigen hexaose type 2 A Antigen Hexaose Type 2 is a antigen hexaose type 2 employed in the research of autoimmune disorders such as rheumatoid arthritand psoriasis. Synonyms: GalNAca-3(fuca-2)Galb-4GlcNAcb-3Galb-4Glc. CAS No. 30461-82-6. Molecular formula: C40H68N2O30. Mole weight: 1056.96. BOC Sciences
ABT 702 Dihydrochloride ABT 702 Dihydrochloride is a potent and selective non-nucleoside adenosine kinase inhibitor with IC50 value of 1.7 nM. ABT 702 displays oral activity in animal models of pain and inflammation. In Mar 2005, ABT 702 was discontinued preclinical for Pain and Rheumatoid arthritis in USA. Uses: Anti-inflammation. Synonyms: ABT702 Dihydrochloride; ABT-702 Dihydrochloride. Grades: 98%. CAS No. 1188890-28-9. Molecular formula: C22H21BrCl2N6O. Mole weight: 536.26. BOC Sciences
Aceclofenac Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) analog of Diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. It has higher anti-inflammatory action than conventional NSAIDs. It is a cytokine inhibitor. It works by blocking the action of a substance in the body called cyclo-oxygenase. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: Preservex; Aceclofenac; YT-919; YT 919; YT919; Airtal; Beofenac. Grades: >98%. CAS No. 89796-99-6. Molecular formula: C16H13Cl2NO4. Mole weight: 354.18. BOC Sciences
Aceclofenac Aceclofenac is an orally active nonsteroidal anti-inflammatory agent (NSAID), with analgesic and anti-inflammatory properties. Aceclofenac is used for the research of osteoarthritis, ankylosing spondylitis, rheumatoid arthritis [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 89796-99-6. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0634. MedChemExpress MCE
Aceclofenac-[13C2,d4] Aceclofenac-[13C2,d4] is the labelled analogue of Aceclofenac, which is an anti-inflammatory and analgesic drug. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis. Synonyms: Aceclofenac-d4,13C2; 2-[(2,6-Dichlorophenyl)-amino]benzeneacetic Acid Carboxymethyl-d4,13C2 Ester; Glycolic Acid [o-(2,6-Dichloroanilino)phenyl]acetate-d4,13C2 Ester; Airtal-d4,13C2; Aceclofar-d4,13C2; Falcol-d4,13C2; Gerbin-d4,13C2; Preservex-d4,13C2; Tresquim-d4,13C2; Zerodol-d4,13C2; 2-(2-(2-((2,6-dichlorophenyl)amino)phenyl-3,4,5,6-d4)acetoxy)acetic-13C2 acid. Grades: >95%. CAS No. 1795019-63-4. Molecular formula: C14[13C]2H9D4Cl2NO4. Mole weight: 360.19. BOC Sciences
Acetylaconitine Acetylaconitine is a diterpenoid alkaloid isolated from the roots of Aconitum kusnezoffii Reichb. It is used in analgesia in rats for the treatment of chronic pain and rheumatoid arthritis. Uses: Acetylaconitine is used in analgesia in rats for the treatment of chronic pain and rheumatoid arthritis. Synonyms: Aconitine 3-acetate; (16beta)-3,8-bis(acetyloxy)-20-ethyl-13,15-dihydroxy-1,6,16-trimethoxy-4-(methoxymethyl)aconitan-14-yl benzoate. Grades: >98%. CAS No. 77181-26-1. Molecular formula: C36H49NO12. Mole weight: 687.77. BOC Sciences 2
Adenosine deaminase from Human, Recombinant Adenosine deaminase is an enzyme (EC 3.5.4.4) involved in purine metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. Present in virtually all mammalian cells, its primary function in Humans is the development and maintenance of the immune system. Applications: Adenosine deaminase (ada) is a key enzyme in purine metabolism and is essential for normal immune function. it is important in the study of immune system diseases such as rheumatoid arthritis. Group: Enzymes. Synonyms: ADA; adenosine deaminase; adenosine aminohydrolase; 9026-93-1; EC 3.5.4.4. Enzyme Commission Number: EC 3.5.4.4. CAS No. 9026-93-1. ADA. Activity: >1 U/mL. Storage: Store at -20°C. Source: E. coli. Species: Human. ADA; adenosine deaminase; adenosine aminohydrolase; 9026-93-1; EC 3.5.4.4. Cat No: NATE-1583. Creative Enzymes

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