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| Product | Description | |
|---|---|---|
| 39S ribosomal protein L34, mitochondrial (58-66) | 39S ribosomal protein L34, mitochondrial (58-66) is a peptide derived from 39S ribosomal protein L34, mitochondrial. MRPL34 (Mitochondrial Ribosomal Protein L34) is a Protein Coding gene. Diseases associated with MRPL34 include Bardet-Biedl Syndrome 5 and Somatization Disorder. Synonyms: L34mt (58-66); Mitochondrial large ribosomal subunit protein bL34m (58-66). |  |
| 40S ribosomal protein S30 | 40S ribosomal protein S30 is an antimicrobial peptide produced by Oncorhynchus mykiss (Rainbow trout, Salmo gairdneri). It has antibacterial activity against Gram-positive bacteria and low activity against Gram-negative bacteria. Synonyms: Lys-Val-His-Gly-Ser-Leu-Ala-Arg-Ala-Gly-Lys. Grade: >95%. Molecular formula: C48H86N18O13. Mole weight: 1123.32. | |
| 50S ribosomal protein L1 | 50S ribosomal protein L1 is an antimicrobial peptide produced by Helicobacter pylori. It has antibacterial and antifungal activity. Synonyms: Ala-Lys-Lys-Val-Phe-Lys-Arg-Leu-Glu-Lys-Leu-Phe-Ser-Lys-Ile-Gln-Asn-Asp-Lys. Grade: >98%. | |
| 50S ribosomal protein L16 3-hydroxylase | The enzyme, characterized from the bacterium Escherichia coli, hydroxylates an arginine residue on the 50S ribosomal protein L16, and is involved in regulation of bacterial ribosome assembly. Group: Enzymes. Synonyms: ycfD (gene name). Enzyme Commission Number: EC 1.14.11.47. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0666; 50S ribosomal protein L16 3-hydroxylase; EC 1.14.11.47; ycfD (gene name). Cat No: EXWM-0666. |  |
| 60S ribosomal protein L30 (95-115) | 60S ribosomal protein L30 (95-115) is a bioactive peptide of 60S ribosomal protein L30 which is encoded by the RPL30 gene. This gene encodes a ribosomal protein that is a component of the 60S subunit. And the protein belongs to the L30E family of ribosomal proteins. | |
| Anti-Ribosomal Protein L26 (N-terminal) antibody produced in rabbit | ~1 mg/mL, affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. |  |
| Recombinant Ribosomal-protein-alanine acetyltransferase from E. coli | Ribosomal-protein-alanine acetyltransferase is an enzyme that catalyzes the chemical reaction: acetyl-CoA + ribosomal-protein L-alanine <-> CoA + ribosomal-protein N-acetyl-L-alanine. Group: Enzymes. Synonyms: ribosomal-protein-alanine N-acetyltransferase; RimJ; EC 2.3.1.128; 113383-52-1. Enzyme Commission Number: EC 2.3.1.128. CAS No. 113383-52-1. Purity: > 80 %. RimJ. Mole weight: 23 kDa. Appearance: Colourless clear liquid. Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Source: E. coli. Species: E. coli. ribosomal-protein-alanine N-acetyltransferase; RimJ; EC 2.3.1.128; 113383-52-1. Cat No: NATE-1019. | |
| Recombinant Ribosomal-protein-serine acetyltransferase from E. coli | This enzyme acetylates the N-terminal serine of ribosomal protein L7/L12. Group: Enzymes. Synonyms: RimL. Purity: > 80 %. RimL. Mole weight: 21 kDa. Appearance: Colourless clear liquid. Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Source: E. coli. Species: E. coli. RimL; Ribosomal-protein-serine acetyltransferase. Cat No: NATE-1020. | |
| ribosomal-protein-alanine N-acetyltransferase | A group of enzymes in Escherichia coli that acetylate the N-terminal alanine residues of specific ribosomal proteins. cf. EC 2.3.1.88, peptide α-N-acetyltransferase. Group: Enzymes. Synonyms: ribosomal protein S18 acetyltransferase. Enzyme Commission Number: EC 2.3.1.128. CAS No. 113383-52-1. RimJ. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2065; ribosomal-protein-alanine N-acetyltransferase; EC 2.3.1.128; 113383-52-1; ribosomal protein S18 acetyltransferase. Cat No: EXWM-2065. | |
| ribosomal protein L3 N5-glutamine methyltransferase | Modifies the glutamine residue in the glycylglycylglutamine (GGQ) motif of ribosomal protein L3 (Gln150 in the protein from the bacterium Escherichia coli). The enzyme does not act on peptide chain release factor 1 or 2. Group: Enzymes. Synonyms: YfcB; PrmB. Enzyme Commission Number: EC 2.1.1.298. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1905; ribosomal protein L3 N5-glutamine methyltransferase; EC 2.1.1.298; YfcB; PrmB. Cat No: EXWM-1905. | |
| [ribosomal protein S12] (aspartate89-C3)-methylthiotransferase | This bacterial enzyme binds two [4Fe-4S] clusters. A bridge of five sulfur atoms is formed between the free Fe atoms of the two [4Fe-4S] clusters. In the first reaction the enzyme transfers a methyl group from AdoMet to the external sulfur ion of the sulfur bridge. In the second reaction the enzyme catalyses the reductive fragmentation of a second molecule of AdoMet, yielding a 5'-deoxyadenosine radical, which then attacks the methylated sulfur atom of the polysulfide bridge, resulting in the transfer of a methylthiol group to aspartate89. The enzyme is a member of the superfamily of S-adenosyl-L-methionine-dependent radical (radical AdoMet) enzymes. Group: Enzymes. Synonyms: RimO; [ribosomal protein S12]-Asp89:sulfur-(sulfur carrier),S-adenosyl-L-methionine C3-methylthiotransferase. Enzyme Commission Number: EC 2.8.4.4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3430; [ribosomal protein S12] (aspartate89-C3)-methylthiotransferase; EC 2.8.4.4; RimO; [ribosomal protein S12]-Asp89:sulfur-(sulfur carrier),S-adenosyl-L-methionine C3-methylthiotransferase. Cat No: EXWM-3430. | |
| Ribosomal protein S26 (47-61) | Ribosomal protein S26 (47-61) is a bioactive peptide of Ribosomal protein S26 which is encoded by the RPS26 gene. This gene encodes a ribosomal protein that is a component of the 40S subunit. And the protein belongs to the S26E family of ribosomal proteins. Synonyms: Small ribosomal subunit protein eS26 (47-61). | |
| S6K1 Inhibitor, PF-4708671 ((2-((4-(5-Ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole, p70 Ribosomal S6 Kinase 1 Inhibitor) | A cell-permeable piperazinyl-pyrimidine compound that acts as an inhibitor against S6K1 (Ki=20nM; IC50=160nM) and MSK1 (IC50=950nM) kinase activity, exhibiting little or much reduced potency against 85 other protein and lipid kinases ( IC50=4.7, 9.2, 65uM, respectively, against RSK1, RSK2, and S6K2; <27% inhibition of the rest at 1uM). Shown to selectively inhibit IGF1- and PMA-stimulated S6K1 substrates phosphorylation in HEK-293 cells in a dose-dependent manner (up to 10uM) in vitro and alleviate heart remodeling and functional damage in a MI (myocardial infarction) model in mice in vivo (75/mg/kg/daily i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?, Molecular Weight: 390.4. US Biological Life Sciences. |  Worldwide |
| 10-DEBC | 10-DEBC is a selective and reversible Akt/PKB inhibitor that inhibits IGF-1-stimulated Akt phosphorylation and activation, and downstream activation of mTOR, p70 S6 kinase, and S6 ribosomal protein. Synonyms: 10H-Phenoxazine-10-butanamine, 2-chloro-N,N-diethyl-; 2-Chloro-N,N-diethyl-10H-phenoxazine-10-butanamine; 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine; 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine; 10-DEBC free base; Akt Inhibitor X; CCG-206734; NCP. Grade: ≥95%. CAS No. 201788-90-1. Molecular formula: C20H25ClN2O. Mole weight: 344.88. | |
| 10-DEBC hydrochloride | 10-DEBC hydrochloride is a selective and reversible Akt/PKB inhibitor suppressing the IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), and inhibiting downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. 10-DEBC hydrochloride inhibits cell growth (IC50 ~ 2-6 μM) and leads to apoptosis in rhabdomyosarcoma cells. Synonyms: 10H-Phenoxazine-10-butanamine, 2-chloro-N,N-diethyl-, hydrochloride (1:1); Akt Inhibitor X; 2-Chloro-N,N-diethyl-10H-phenoxazine-10-butanamine hydrochloride; 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride; 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine hydrochloride. Grade: ≥99% by HPLC. CAS No. 925681-41-0. Molecular formula: C20H25N2OCl.HCl. Mole weight: 381.34. | |
| 10-DEBC hydrochloride | Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5uM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ~ 2-6uM) and induces apoptosis in rhabdomyosarcoma cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 925681-41-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C20H25N2OCl.HCl, Method for Determining. US Biological Life Sciences. | Worldwide |
| 14-Hydroxyclarithromycin | 14-Hydroxyclarithromycin is an impurity of Erythromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: Erythromycin, 14-hydroxy-6-O-methyl-; 14-Hydroxy-6-O-methylerythromycin; 14-OH-Clarithromycin; Clarithromycin Impurity 23; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-12,13-dihydroxy-14-[(1S)-1-hydroxyethyl]-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione; A 62671; Antibiotic A 62671. Grade: 95%. CAS No. 110671-78-8. Molecular formula: C38H69NO14. Mole weight: 763.95. | |
| 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase | KsgA introduces the most highly conserved ribosomal RNA modification, the dimethylation of adenine1518 and adenine1519 in 16S rRNA. Strains lacking the methylase are resistant to kasugamycin. Group: Enzymes. Synonyms: S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase; KsgA; ksgA methyltransferase. Enzyme Commission Number: EC 2.1.1.182. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1781; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; EC 2.1.1.182; S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase; KsgA; ksgA methyltransferase. Cat No: EXWM-1781. | |
| 16S rRNA (guanine527-N7)-methyltransferase | The enzyme specifically methylates guanine527 at N7 in 16S rRNA. Group: Enzymes. Synonyms: ribosomal RNA small subunit methyltransferase G; 16S rRNA methyltransferase RsmG; GidB; rsmG (gene name). Enzyme Commission Number: EC 2.1.1.170. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1768; 16S rRNA (guanine527-N7)-methyltransferase; EC 2.1.1.170; ribosomal RNA small subunit methyltransferase G; 16S rRNA methyltransferase RsmG; GidB; rsmG (gene name). Cat No: EXWM-1768. | |
| 16S rRNA pseudouridine516 synthase | The enzyme is specific for uridine516 in 16S rRNA. In vitro, the enzyme does not modify free 16S rRNA. The preferred substrate is a 5'-terminal fragment of 16S rRNA complexed with 30S ribosomal proteins. Group: Enzymes. Synonyms: 16S RNA pseudouridine516 synthase; 16S PsiI516 synthase; 16S RNA ψ516 synthase; RNA pseudouridine synthase RsuA; RsuA; 16S RNA pseudouridine 516 synthase. Enzyme Commission Number: EC 5.4.99.19. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5558; 16S rRNA pseudouridine516 synthase; EC 5.4.99.19; 16S RNA pseudouridine516 synthase; 16S PsiI516 synthase; 16S RNA ψ516 synthase; RNA pseudouridine synthase RsuA; RsuA; 16S RNA pseudouridine 516 synthase. Cat No: EXWM-5558. | |
| 23S rRNA (adenine1618-N6)-methyltransferase | The recombinant YbiN protein is able to methylate partially deproteinized 50 S ribosomal subunit, but neither the completely assembled 50 S subunits nor completely deproteinized 23 S rRNA. Group: Enzymes. Synonyms: rRNA large subunit methyltransferase F; YbiN protein; rlmF (gene name); m6A1618 methyltransferase. Enzyme Commission Number: EC 2.1.1.181. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1780; 23S rRNA (adenine1618-N6)-methyltransferase; EC 2.1.1.181; rRNA large subunit methyltransferase F; YbiN protein; rlmF (gene name); m6A1618 methyltransferase. Cat No: EXWM-1780. | |
| 23S rRNA (adenine2030-N6)-methyltransferase | The recombinant RlmJ protein is most active in methylating deproteinized 23S ribosomal subunit, and does not methylate the completely assembled 50S subunits. Group: Enzymes. Synonyms: YhiR protein; rlmJ (gene name); m6A2030 methyltransferase. Enzyme Commission Number: EC 2.1.1.266. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1871; 23S rRNA (adenine2030-N6)-methyltransferase; EC 2.1.1.266; YhiR protein; rlmJ (gene name); m6A2030 methyltransferase. Cat No: EXWM-1871. | |
| 23S rRNA (guanine1835-N2)-methyltransferase | The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate. The enzyme specifically methylates guanine1835 at N2 in 23S rRNA. Group: Enzymes. Synonyms: ygjO (gene name); rlmG (gene name); ribosomal RNA large subunit methyltransferase G. Enzyme Commission Number: EC 2.1.1.174. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1772; 23S rRNA (guanine1835-N2)-methyltransferase; EC 2.1.1.174; ygjO (gene name); rlmG (gene name); ribosomal RNA large subunit methyltransferase G. Cat No: EXWM-1772. | |
| 23S rRNA (guanine2535-N1)-methyltransferase | Streptomyces viridochromogenes produces the antibiotic avilamycin A which binds to the 50S ribosomal subunit to inhibit protein synthesis. To protect itself from the antibiotic, Streptomyces viridochromogenes utilizes two methyltransferases, 23S rRNA (guanine2535-N1)-methyltransferase and EC 2.1.1.208 [23S rRNA (uridine2479-2-O)-methyltransferase], whose actions confer avilamycin resistance to the RNA. Group: Enzymes. Synonyms: AviRa. Enzyme Commission Number: EC 2.1.1.209. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1810; 23S rRNA (guanine2535-N1)-methyltransferase; EC 2.1.1.209; AviRa. Cat No: EXWM-1810. | |
| 23S rRNA (guanine745-N1)-methyltransferase | The enzyme specifically methylates guanine745 at N1 in 23S rRNA. Group: Enzymes. Synonyms: Rlma(I); Rlma1; 23S rRNA m1G745 methyltransferase; YebH; RlmAI methyltransferase; ribosomal RNA(m1G)-methylase (ambiguous); rRNA(m1G)methylase (ambiguous); RrmA (ambiguous); 23S rRNA:m1G745 methyltransferase. Enzyme Commission Number: EC 2.1.1.187. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1786; 23S rRNA (guanine745-N1)-methyltransferase; EC 2.1.1.187; Rlma(I); Rlma1; 23S rRNA m1G745 methyltransferase; YebH; RlmAI methyltransferase; ribosomal RNA(m1G)-methylase (ambiguous); rRNA(m1G)methylase (ambiguous); RrmA (ambiguous); 23S rRNA:m1G745 methyltransferase. Cat No: EXWM-1786. | |
| 23S rRNA (uridine2479-2'-O)-methyltransferase | Streptomyces viridochromogenes produces the antibiotic avilamycin A which binds to the 50S ribosomal subunit to inhibit protein synthesis. To protect itself from the antibiotic, Streptomyces viridochromogenes utilizes two methyltransferases, 23S rRNA (uridine2479-2'-O)-methyltransferase and EC 2.1.1.209 [23S rRNA (guanine2535-N1)-methyltransferase], whose actions confer avilamycin resistance to the RNA. Group: Enzymes. Synonyms: AviRb. Enzyme Commission Number: EC 2.1.1.208. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1809; 23S rRNA (uridine2479-2'-O)-methyltransferase; EC 2.1.1.208; AviRb. Cat No: EXWM-1809. | |
| 23S rRNA (uridine2552-2'-O)-methyltransferase | The enzyme catalyses the 2'-O-methylation of the universally conserved U2552 in the A loop of 23S rRNA. Group: Enzymes. Synonyms: Um(2552) 23S ribosomal RNA methyltransferase; heat shock protein RrmJ; RrmJ; FTSJ; Um2552 methyltransferase. Enzyme Commission Number: EC 2.1.1.166. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1763; 23S rRNA (uridine2552-2'-O)-methyltransferase; EC 2.1.1.166; Um(2552) 23S ribosomal RNA methyltransferase; heat shock protein RrmJ; RrmJ; FTSJ; Um2552 methyltransferase. Cat No: EXWM-1763. | |
| 2',5-Difluoro-2'-deoxycytidine | 2',5-Difluoro-2'-deoxycytidine has potent activity against HCV and toxicity to ribosomal RNA (rRNA). Synonyms: 2'-deoxy-2',5-difluorocytidine; Cytidine, 2'-deoxy-2',5-difluoro-; 4-amino-5-fluoro-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one. Grade: ≥95%. CAS No. 581772-30-7. Molecular formula: C9H11F2N3O4. Mole weight: 263.20. | |
| 25S rRNA (cytosine2870-C5)-methyltransferase | The enzyme, found in eukaryotes, is specific for cytosine2870 of the 25S ribosomal RNA. The numbering corresponds to the enzyme from the yeast Saccharomyces cerevisiae. Group: Enzymes. Synonyms: NOP2 (gene name). Enzyme Commission Number: EC 2.1.1.310. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1918; 25S rRNA (cytosine2870-C5)-methyltransferase; EC 2.1.1.310; NOP2 (gene name). Cat No: EXWM-1918. | |
| 2-Methylthio-N6-iso-pentenyladenosine | 2-Methylthio-N6-isopentenyladenosine is located at position 37 in tRNAs that read codons starting with uridine. 2-Methylthio-N6-isopentenyladenosine in trpT(Su9) suppressor tRNA increase the efficiency of the tRNA by protecting it from ribosomal proofreading which is induced by codon context. Synonyms: Adenosine, N-(3-methyl-2-butenyl)-2-(methylthio)-; 2-Methyl-thio-N6-isopentyladenosine; N6-Isopentenyl-2-thiomethyladenosine; N-(3-Methyl-2-buten-1-yl)-2-(methylsulfanyl)adenosine; (2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(6-((3-methylbut-2-en-1-yl)amino)-2-(methylthio)-9H-purin-9-yl)tetrahydrofuran-3,4-diol. Grade: ≥95%. CAS No. 20859-00-1. Molecular formula: C16H23N5O4S. Mole weight: 381.45. | |
| 2-Methylthio-N6-isopentenyladenosine-d6 | Isotope labelled 2-Methylthio-N6-isopentenyladenosine is located at position 37 in tRNAs that read codons starting with uridine. 2-Methylthio-N6-isopentenyladenosine in trpT(Su9) suppressor tRNA increase the efficiency of the tRNA by protecting it from ribosomal proofreading which is induced by codon context. Group: Biochemicals. Grades: Highly Purified. CAS No. 1258839-12-1. Pack Sizes: 1mg, 10mg. Molecular Formula: C16H17D6N5O4S, Molecular Weight: 387.49. US Biological Life Sciences. | Worldwide |
| 2'-O-MethylpseudoUridine-5'-Triphosphate Lithium | 2'-O-MethylpseudoUridine-5'-Triphosphate Lithium is a nucleotide analog commonly used in molecular biology research to investigate RNA modification and translation. It has been shown to enhance ribosomal reading efficiency and suppress frameshifting during translation. It may also play a role in regulating immune function and has potential therapeutic applications in autoimmunity and inflammatory diseases. Synonyms: 2'-O-Methylpseudo-UTP tetralithium salt. Grade: ≥90% by AX-HPLC. Molecular formula: C10H13Li4N2O15P3. Mole weight: 521.89. | |
| 3-De[(2,6-dideoxy-3-C-methyl-3-o-methyl-a-L-ribo-hexopyranosyl)oxy]-10,11-didehydro-11-deoxy-6-o-methyl-3-oxo-erythromycin 2'-acetate | 3-De[(2,6-dideoxy-3-C-methyl-3-o-methyl-a-L-ribo-hexopyranosyl)oxy]-10,11-didehydro-11-deoxy-6-o-methyl-3-oxo-erythromycin 2'-acetate is a derivative of Erythromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: 2'-O-Benzoyl-3-O-de[(2,6-dideoxy-3-c-methyl-3-O-methyl-a-L-ribohexopyranosyl)oxy]-11-deoxy-10,11-didehydro-6-O-methyl-3-oxoerythromycin; Erythromycin, 3-de[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-10,11-didehydro-11-deoxy-6-O-methyl-3-oxo-, 2'-acetate; (2S,3R,4S,6R)-4-(Dimethylamino)-2-{[(3R,5R,6R,7R,9R,11E,13S,14R)-14-ethyl-13-hydroxy-7-methoxy-3,5,7,9,11,13-hexamethyl-2,4,10-trioxooxacyclotetradec-11-en-6-yl]oxy}-6-methyltetrahydro-2H-pyran-3-yl benzoate. Grade: 95%. CAS No. 160145-82-4. Molecular formula: C32H53NO10. Mole weight: 611.76. | |
| 4'',6-Di-O-methylerythromycin-[d3] | 4'',6-Di-O-methylerythromycin-[d3] is the labelled analogue of 4'',6-Di-O-methylerythromycin, which is a derivative of Erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: 4'',6-Di-O-methylerythromycin-d3; 4'-O-Methylclarithromycin-d3. Molecular formula: C39H68D3NO13. Mole weight: 765.00. | |
| 5-Fluorocytidine | 5-Fluorocytidine is a member of cytidines, inhibits maturation of the 45S ribosomal RNA precursor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2341-22-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-W039722. |  |
| 6-O-Methyl-2',4''-bis-O-(trimethylsilyl)-9-[O-(1-ethoxy-1-methylethyl)oxime] Erythromycin | 6-O-Methyl-2',4''-bis-O-(trimethylsilyl)-9-[O-(1-ethoxy-1-methylethyl)oxime] Erythromycin is a derivative of Erythromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: Erythromycin, 6-O-methyl-2',4''-bis-O-(trimethylsilyl)-, 9-[O-(1-ethoxy-1-methylethyl)oxime; Intermediate of Clarithromycin; Erythromycin Impurity 11; (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-({(2S,3R,4S,6R)-4-(Dimethylamino)-6-methyl-3-[(trimethylsilyl)oxy]tetrahydro-2H-pyran-2-yl}oxy)-10-{[(2-ethoxy-2-propanyl)oxy]imino}-14-ethyl-12,13-dihydroxy-7-methoxy-4-({(2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-[(trimethylsilyl)oxy]tetrahydro-2H-pyran-2-yl}oxy)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one. Grade: ≥95%. CAS No. 119665-62-2. Molecular formula: C49H96N2O14Si2. Mole weight: 993.46. | |
| 6-O-Methyl-2',4'-bis-O-(trimethylsilyl)erythromycin 9-[O-(1-methoxy-1-methylethyl)oxime] | 6-O-Methyl-2',4'-bis-O-(trimethylsilyl)erythromycin 9-[O-(1-methoxy-1-methylethyl)oxime] is a derivative of Erythromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: Erythromycin, 6-O-methyl-2',4''-bis-O-(trimethylsilyl)-, 9-[O-(1-methoxy-1-methylethyl)oxime]; Erythromycin Impurity 7; 2',4''-O-Bis(trimethylsilyl)-6-O-methylerythromycin A 9-[O-(1-methoxy-1-methylethyl)oxime]; (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-({(2S,3R,4S,6R)-4-(Dimethylamino)-6-methyl-3-[(trimethylsilyl)oxy]tetrahydro-2H-pyran-2-yl}oxy)-14-ethyl-12,13-dihydroxy-7-methoxy-4-({(2R,4R,5S,6S)-4-methoxy-4,6-dimethyl-5-[(trimethylsilyl)oxy]tetrahydro-2H-pyran-2-yl}oxy)-10-{[(2-methoxy-2-propanyl)oxy]imino}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one. Grade: ≥95%. CAS No. 119699-81-9. Molecular formula: C48H94N2O14Si2. Mole weight: 979.44. | |
| 7-Propargylamino-7-deaza-ddATP - ATTO-425 | 7-Propargylamino-7-deaza-ddATP - ATTO-425 is a fluorescent nucleotide analog extensively used in biomedical research for labeling and detecting DNA fibers dynamics. It has been employed to study the molecular basis of DNA replications, identifying remotely induced mutations, and studying ribosomal RNA transcription, amongst other applications. Synonyms: 7-Deaza-7-propargylamino-2',3'-dideoxyadenosine-5'-triphosphate, labeled with ATTO 425, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C36H45N6O16P3 (free acid). Mole weight: 910.70 (free acid). | |
| 8-Epi-11,12-epoxy Erythromycin A | An impurity of Erythromycin. Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: 8-Epi-11,12-epoxy Erythromycin A. Grade: > 95%. Molecular formula: C37H65NO12. Mole weight: 715.93. | |
| (9E)-Erythromycin 9-[O-[[(2-Methoxyethoxy)methoxy]methyl]oxime] | (9E)-Erythromycin 9-[O-[[(2-Methoxyethoxy)methoxy]methyl]oxime] is a derivative of Erythromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Uses: Roxithromycin impurity g, a roxithromycin. Synonyms: Erythromycin 9-(E)-[O-[[(2-Methoxyethoxy)methoxy]methyl]oxime]; Erythromycin, 9-[O-[[(2-methoxyethoxy)methoxy]methyl]oxime], (9E)-; Roxithromycin EP Impurity G. Grade: 95%. CAS No. 425365-64-6. Molecular formula: C42H78N2O16. Mole weight: 867.07. | |
| (9E)-Erythromycin A oxime | (9E)-Erythromycin A oxime is a derivative of erythromycin A, where the ketone group at the C9 position of the lactone ring is converted to an oxime group (-C=NOH) in the (E)-configuration. This structural modification can enhance the compound's chemical stability and resistance to acid degradation, which is beneficial for oral bioavailability. Like erythromycin, this oxime derivative retains the ability to inhibit bacterial protein synthesis by binding to the 50S ribosomal subunit, exhibiting bacteriostatic activity. It may be investigated for improved pharmacokinetic properties or as an intermediate in the synthesis of macrolide derivatives for combating bacterial resistance. Synonyms: Erythromycin A oxime; (E)-Erythromycin A oxime; (E)-Erythromycin oxime; Erythromycin, 9-oxime, (9E)-; (9E)-Erythromycin, 9-oxime; (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(hydroxyimino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one. Grade: ≥95%. CAS No. 111321-02-9. Molecular formula: C37H68N2O13. Mole weight: 748.95. | |
| (9S)-9-Deoxo-12-deoxy-9,12-epoxyerythromycin | (9S)-9-Deoxo-12-deoxy-9,12-epoxyerythromycin is a derivative of Erythromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: Erythromycin, 9-deoxo-12-deoxy-9,12-epoxy-, (9S)-; (1S,2R,5R,6S,7S,8R,9R,11R,12S,13R,14R)-8-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-9,14-dihydroxy-6-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-1,5,7,9,11,13-hexamethyl-3,15-dioxabicyclo[10.2.1]pentadecan-4-one; A 69328. Grade: >95%. CAS No. 134108-11-5. Molecular formula: C37H67NO12. Mole weight: 717.93. | |
| (9S)-9-Deoxo-9-(propylamino)erythromycin | (9S)-9-Deoxo-9-(propylamino)erythromycin is a derivative of Erythromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains. Synonyms: Erythromycin, 9-deoxo-9-(propylamino)-, (9S)-; 9-N-(1-propyl)erythromyclamine; LY 281389; (3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,7,9,11,13-hexamethyl-10-(propylamino)oxacyclotetradecan-2-one. Grade: 95%. CAS No. 119904-03-9. Molecular formula: C40H76N2O12. Mole weight: 777.04. | |
| Amikacin disulfate | Amikacin disulfate (BAY 41-6551 dissulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin disulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin disulfate is very active against most Gram-negative bacteria including gentamicin - and tobramycin-resistant strains. Amikacin disulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 41-6551 disulfate. CAS No. 39831-55-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0509B. | |
| Amikacin hydrate | Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin hydrate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin hydrate is very active against most Gram-negative bacteria including gentamicin - and tobramycin-resistant strains. Amikacin hydrate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 41-6551 hydrate. CAS No. 1257517-67-1. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-B0509. | |
| Amikacin sulfate | Amikacin sulfate (BAY 41-6551 sulfate) is an aminoglycoside antibiotic and a semisynthetic analog of kanamycin. Amikacin sulfate is bactericidal, acting directly on the 30S and 50S bacerial ribosomal subunits to inhibit protein synthesis. Amikacin sulfate is very active against most Gram-negative bacteria including gentamicin - and tobramycin-resistant strains. Amikacin sulfate also inhibits the infections caused by susceptible Nocardia and nontuberculous mycobacteria [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 41-6551 sulfate. CAS No. 149022-22-0. Pack Sizes: 50 mg; 100 mg. Product ID: HY-107813. | |
| Amikacin Sulfate Multivesicular Liposome | Amikacin sulfate is an aminoglycoside that inhibits protein synthesis by binding tightly to the A site of 30S ribosomal 16SrRNA. This product is a pre-formulated liposome with amikacin sulfate. It is only for research purposes and for the injection to laboratory animals. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. |  |
| Anhydrotetracycline hydrochloride | Anhydrotetracycline acts as an inducer of tetracycline resistance genes by binding to and inactivating the tetracycline repressor TetR to allow expression of downstream genes of the tetr promoter. However, anhydrotetracycline binds to the TetR repressor with higher affinity without toxic effects. Anhydrotetracycline poorly binds the 30S ribosomal subunit, the concentration of anhydrotetracycline that inhibits eukaryotic cell growth is more than 1,000-fold above the dose that alters transcription through TetR. Synonyms: (4S,4aS,12aS)-4-(Dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydro-2-tetracenecarboxamide hydrochloride (1:1). Grade: ≥98%. CAS No. 13803-65-1. Molecular formula: C22H22N2O7.HCl. Mole weight: 462.88. | |
| Anisomycin (Flagecidin, Antibiotic SA 3097C1, Antibiotic PA 106, Anhydroscopin A, NSC) | Anisomycin is a phenyl methyl enepyrrolidine first isolated from Streptomyces griseolus in 1954 as an antiprotozoan with antifungal activity. Anisomycin acts as an inhibitor of protein synthesis by binding to the 60S ribosomal subunit. Interestingly, anisomycin has found use for the induction of amnesia in animal models. More recently, anisomycin has been demonstrated to induce apoptosis, to be a selective signalling agonist, to activate mitogen-activated protein (MAP) kinases and to be immunomodulatory via its action on T cells. Group: Biochemicals. Alternative Names: ((2R,3S,4S)-2-(4-Methoxybenzyl)-3,4-pyrrolidinediol-3-acetate, 2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate. Grades: Highly Purified. CAS No. 22862-76-6. Pack Sizes: 25mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| Arg-AMS | Arg-AMS (compound 24) is a potent nanomolar inhibitor of arginyl tRNA synthetase, which displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 301351-95-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-112862. | |
| Aureusimine B | It is an inhibitor of the protease Calpain produced by the strain of Streptomyces sp. SC433. It is a small molecular weight monoketopiperazine formed non-ribosomally by the fusion of phenylalanine and valin. Synonyms: Phevalin; 3-(1-Methylethyl)-6-(phenylmethyl)-2(1H)-pyrazinone; 6-Benzyl-3-isopropylpyrazin-2-one. Grade: >95% by HPLC. CAS No. 170713-71-0. Molecular formula: C14H16N2O. Mole weight: 228.29. | |
| Azithromycin EP Impurity B | An impurity of Azithromycin. Azithromycin B is a macrolide antibiotic that is structurally related to erythromycin and contains a 15-membered ring. It is known for its broad-spectrum activity against a variety of bacterial infections. Azithromycin works by binding to the 50S ribosomal subunit of bacteria, which inhibits their protein synthesis. This medication is used to treat several types of infections, including respiratory, enteric, and genitourinary infections, as well as some sexually transmitted diseases. Synonyms: Azithromycin B; 1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-4,10-dihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3R,4R,5R,8R,10R,11R,12R,13S,14R)-; 3-Deoxyazithromycin; Azithromycin Impurity B. Grade: >95%. CAS No. 307974-61-4. Molecular formula: C38H72N2O11. Mole weight: 733.00. | |
| Bacteriocin microcin B17 | Bacteriocin microcin B17 is an antimicrobial peptide produced by Escherichia coli. It has antimicrobial activity. MccB17 was the first compound discovered from the Thiazole/Oxazole-Modified Microcins (TOMMs) family and the Linear Azole-containing peptides (LAPs). These ribosomal peptides are post-translationally modified to convert serine and cysteine residues into oxazole and thiazole rings. Synonyms: mcbA; MccB17. Grade: >98%. | |
| BIX 02565 | BIX 02565 is a potent ribosomal S6 kinase 2 (RSK2) inhibitor with IC50 of 1.1 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1311367-27-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16104. | |
| Blasticidin S Hydrochloride | Blasticidin S is a peptide nucleoside antibiotic that is used as a selection agent for transformed cells that contain the resistance genes bls, bsr, or BSD. It specifically inhibits protein synthesis in both prokaryotes and eukaryotes by interfering with the peptide bound formation in the ribosomal machinery. Group: Biochemicals. Alternative Names: Blasticidine S; Blasticidin S HCl. Grades: Highly Purified. CAS No. 3513-3-9. Pack Sizes: 25mg, 100mg, 250mg. Molecular Formula: C10H11N3·HCl, Molecular Weight: 458.9. US Biological Life Sciences. | Worldwide |
| BMH-21 | BMH-21 is a potent small molecule DNA intercalator. BMH-21 binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription. Uses: Enzyme inhibitors. Synonyms: BMH-21; BMH 21; BMH21. Grade: >98%. CAS No. 896705-16-1. Molecular formula: C21H22N4O2. Mole weight: 362.43. | |
| BRD 7389 | BRD 7389 is a ribosomal S6 kinase (RSK) inhibitor (IC50 = 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2, respectively). It upregulates insulin expression in mouse αTC1 pancreatic α cells. Synonyms: BRD7389; BRD-7389; BRD 7389; BAS 05532738; BAS05532738; BAS-05532738; 1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione. Grade: ≥97% by HPLC. CAS No. 376382-11-5. Molecular formula: C24H18N2O2. Mole weight: 366.41. | |
| Capreomycin sulfate | Capreomycin sulfate is a macrocyclic peptide antibiotic that inhibits phenylalanine synthesis in mycobacterial ribosomal translation. Capreomycin sulfate has anti-amyloidogenic and pro-fibrinolytic activities, reducing amyloid-induced cytotoxicity by inhibiting the occurrence of amyloid fibrillation. Capreomycin sulfate can be used in the study of multidrug-resistant tuberculosis, type 2 diabetes, Alzheimer's disease and Parkinson's disease [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 1405-37-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-17566. | |
| Carnosol | Carnosol is a potent Ribosomal S6 Kinase (RSK2) inhibitor that could be useful for treating gastric cancer, with an IC 50 of ~5.5 μM [1]. Carnosol, a Nrf2 activator, increases the nuclear levels of Nrf2 and can promote the expression of heme oxygenase 1 (HMOX1) [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 5957-80-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N0643. | |
| Chloramphenicol | Chloramphenicol is a chlorine-containing antibiotic produced by Streptomyces venezuelae. It has a wide spectrum of activity against gram-positive and gram-negative cocci and bacilli (including anaerobes), Rickettsia, Mycoplasma, and Chlamydia. It inhibits prokaryotic protein synthesis by attaching to the 50S ribosomal subunit. This inhibits peptidyltransferase, thereby preventing the formation of peptide bonds. It also inhibits protein synthesis in mitochondria which accounts for its toxic effects that cause aplastic anemia. Chloramphenicol has other adverse effects such as bone marrow depression, and gray baby syndrome. Its use is limited to serious infections such as those where resistance to other antibiotics occurs. It is still widely used in the treatment of typhoid fever, meningitis and eye infections. Group: Biochemicals. Alternative Names: 2, 2-Dichloro-N-[ (1R, 2R) -2-hydroxy-1- (hydroxymethyl) -2- (4-nitrophenyl) ethyl]Acetamide; D-threo-N-Dichloroacetyl-1-p-nitrophenyl-2-amino-1,3-propanediol; Anacetin; Aquamycetin; Chlorocid; Chloroptic; Fenicol; Pantovernil; Paraxin; Chloromycetin. Grades: Molecular Biology Grade. CAS No. 56-75-7. Pack Sizes: 25g, 100g, 250g, 500g, 1Kg. Molecular Formula: C11H12Cl2N2O5, Molecular Weight: 323.13. US Biological Life Sciences. | Worldwide |
| Chloramphenicol (HRP) | Chloramphenicol is a broad spectrum antibiotic isolated from the soil bacterium Streptomyces venezuela. It is bacteriostatic in action and inhibits bacterial protein synthesis by binding to the ribosomal 50S subunit. Chloramphenicol has been used to treat a wide range of human and animal conditions. Chloramphenicol is well absorbed orally and is distributed widely in body fluids. It is metabolized in the liver to the inactive glucuronide. Both chloramphenicol and the glucuronide metabolite are excreted in urine. Metabolism studies in food producing animals demonstrated numerous differences in metabolic profiles between bovine, porcine and poultry species, although the parent drug was the major metabolite identified in muscle for all species. Group: Biochemicals. Grades: Purified. Pack Sizes: 500ul. US Biological Life Sciences. | Worldwide |
| Chloramphenicol succinate sodium salt | Chloramphenicol is a chlorine-containing antibiotic produced by Streptomyces venezuelae. It has a wide spectrum of activity against gram-positive and gram-negative cocci and bacilli (including anaerobes), Rickettsia, Mycoplasma, and Chlamydia. It inhibits prokaryotic protein synthesis by attaching to the 50S ribosomal subunit. This inhibits peptidyltransferase, thereby preventing the formation of peptide bonds. It also inhibits protein synthesis in mitochondria which accounts for its toxic effects that cause aplastic anemia. Chloramphenicol has other adverse effects such as bone marrow depression, and gray baby syndrome. Its use is limited to serious infections such as those where resistance to other antibiotics occurs. It is still widely used in the treatment of typhoid fever, meningitis and eye infections. Group: Biochemicals. Alternative Names: Chloramphenicol alpha-succinate. Grades: Molecular Biology Grade. CAS No. 982-57-0. Pack Sizes: 5g, 25g. US Biological Life Sciences. | Worldwide |
| CKI-7 free base | CKI-7 free base is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC50 of 6 μM and a Ki of 8.5 μM. CKI-7 free base also inhibits SGK, ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). Uses: Found to have a potent inhibitory action against casein kinase 1 completely with respect to atp and a much weaker effect on casein kinase 2 and other protein kinases. Synonyms: CKI-7; CKI 7; 8-Isoquinolinesulfonamide, N-(2-aminoethyl)-5-chloro-. Grade: 95%. CAS No. 120615-25-0. Molecular formula: C11H12ClN3O2S. Mole weight: 285.75. | |
| CKI-7 free base | CKI-7 free base is a potent and ATP-competitive casein kinase 1 (CK1) inhibitor with an IC 50 of 6 μM and a K i of 8.5 μM. CKI-7 free base is a selective Cdc7 kinase inhibitor. CKI-7 free base also inhibits SGK , ribosomal S6 kinase-1 (S6K1) and mitogen- and stress-activated protein kinase-1 (MSK1). CKI-7 free base has a much weaker effect on casein kinase II and other protein kinases [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 120615-25-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133028. | |
| Clindamycin | Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis , possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 18323-44-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-B1455. | |
| Clindamycin | Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla). Clindamycin also can be used for researching malaria. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-threo-alpha-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-(((1-methyl-4-propyl-2-pyrrolidinyl)carbonyl)amino)-1-thio-, (2S-trans)-. Product Category: Inhibitors. CAS No. 18323-44-9. Molecular formula: C18H33ClN2O5S. Mole weight: 424.98. Product ID: ACM18323449. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Clindamycin hydrochloride | Clindamycin (hydrochloride) is a semisynthetic lincosamide antibiotic, which inhibits protein synthesis by acting on the 50S ribosomal. Uses: Scientific research. Group: Signaling pathways. CAS No. 21462-39-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 1 g; 5 g. Product ID: HY-B0408A. | |
| Clindamycin hydrochloride monohydrate | Clindamycin is an antibiotic in the lincosamide class which binds the bacterial 50S ribosomal subunit and interferes with protein synthesis. CAS No. 58207-19-5. Molecular formula: C18H36Cl2N2O6S. Mole weight: 479.46. | |
| cyclopeptine synthase | Cyclopeptine synthase is the key enzyme of benzodiazepine alkaloid biosynthesis in the fungus Penicillium cyclopium. The enzyme is a non-ribosomal peptide synthase. Group: Enzymes. Enzyme Commission Number: EC 6.3.2.40. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5758; cyclopeptine synthase; EC 6.3.2.40. Cat No: EXWM-5758. | |
| cypemycin cysteine dehydrogenase (decarboxylating) | Cypemycin, isolated from the bacterium Streptomyces sp. OH-4156, is a peptide antibiotic, member of the linaridins, a class of posttranslationally modified ribosomally synthesized peptides. The enzyme decarboxylates and reduces the C-terminal L-cysteine residue, producing a reactive ethenethiol group that reacts with a dethiolated cysteine upstream to form an aminovinyl-methyl-cysteine loop that is important for the antibiotic activity of the mature peptide. Group: Enzymes. Synonyms: cypemycin decarboxylase; CypD. Enzyme Commission Number: EC 1.3.99.36. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1436; cypemycin cysteine dehydrogenase (decarboxylating); EC 1.3.99.36; cypemycin decarboxylase; CypD. Cat No: EXWM-1436. | |
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