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1-O-tert-Butyldimethylsilyl-2-azido-2-deoxy-b-D-glucopyranoside, an indispensable compound in the biomedical sector, showcases its significance in the synthesis of glycosidic compounds and the investigation of carbohydrate-mediated interactions. In the pursuit of antiviral drugs, focusing on restraining glycosidase enzymes to combat viral infections, this product emerges as an invaluable asset. Its multifaceted application and pivotal role render it indispensable within the realm of drug development. Synonyms: 3,4,6-Tri-O-acetyl-2-azido-1-O-[tert-butyl(dimethyl)silyl]-2-deoxy-beta-D-glucopyranose; 1-O-tert-Butyldimethylsilyl 2-azido-2-deoxy-beta-D-glucopyranoside 3,4,6-triacetate; [(2R,3S,4R,5R,6S)-3,4-diacetyloxy-5-azido-6-[tert-butyl(dimethyl)silyl]oxyoxan-2-yl]methyl acetate; DTXSID40584091; IFAXCGVPFHELQE-HHARLNAUSA-N; 1-O-tert-Butyldimethylsilyl 2-azido-2-deoxy- beta -D-glucopyranoside 3,4,6-triacetate; tert-Butyldimethylsilyl 3,4,6-tri-O-acetyl-2-azido-2-deoxy-beta-D-glucopyranoside; tert-Butyldimethylsilyl-3,4,6-tri-O-acetyl-2-azido-2-deoxy-ss-D-glucopyranoside. CAS No. 99049-65-7. Molecular formula: C12H25N3O5Si. Mole weight: 319.43.
Cetirizine Impurity 28
Cetirizine Impurity 28. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sec-butyl 2- (2- (4- ( (R)- (4-chlorophenyl) (phenyl)methyl)piperazin-1-yl)ethoxy)acetate. Molecular Formula: C25H33ClN2O3. Mole Weight: 444.99. Catalog: APB04248.
Cetirizine Impurity 42
Cetirizine Impurity 42. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sec-butyl 2- (2- (4- ( (4-chlorophenyl) (phenyl)methyl)piperazin-1-yl)ethoxy)acetate. Molecular Formula: C25H33ClN2O3. Mole Weight: 444.99. Catalog: APB04238.
DAPT
Cell permeable gamma-secretase inhibitor (IC50 = 115nM for total beta-amyloid, IC50 = 200nM for beta-amyloid 1-42). Reduces Abeta levels in vivo. Blocks the proteolytic processing of neurotrophin receptor alike death domain protein (NRADD). Does not inhibit persenilinase. Notch processing inhibitor. Enhances neuronal differentiation independent of sonic hedgehog (Shh) signaling. CDK5 activity inhibitor. Apoptosis enhancer. Group: Biochemicals. Alternative Names: (S)-Tert-butyl 2- ( (S) -2- (2- (3, 5-difluorophenyl) acetamido) propanamido) -2-phenylacetate; N-S-phenylglycine tert.butyl ester; GSI-IX; Secretase, gamma Inhibitor IX. Grades: Highly Purified. CAS No. 208255-80-5. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??F?N?O?. US Biological Life Sciences.
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DAPT
DAPT, also called γ-Secretase Inhibitor IX, is a potent and selective inhibitor of γ-secretase which leads to a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (total Aβ: IC50 = 115 nM (human); Aβ42: IC50 = 200 nM (human)). Uses: Differentiation. Synonyms: tert-butyl (2S) -2-[[ (2S) -2-[[2- (3, 5-difluorophenyl) acetyl]amino]propanoyl]amino]-2-phenylacetate; dapt; 208255-80-5; DAPT (GSI-IX); gamma-Secretase Inhibitor IX; CHEBI:86193; MFCD04974585; DAPT, GSI-IX; InSolution™ gamma-Secretase Inhibitor IX; N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester; N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester(DAPT); C23H26F2N2O4; GSIIX; S2215_Selleck; AC1NSKCB; PubChem22436; GSI-IX; DAPT,GSI-IX; DAPT; DAPT - GSI-IX; MLS006010075; CHEMBL255682; QCR-29; SCHEMBL1360313; DTXSID00415519; AOB33372; DAPT-Supplied by Selleck Chemicals; EBD16444; ZINC1549363; ABP000317; ZINC01549363; AKOS024457209; CS-0264; NCGC00167803-03; (3,5-Difluorophenylacetyl)-Ala-Phg-OtBu; AC-23163; AK477268; BC649954; CJ-24363; HY-13027; KB-57235; SMR004701228; AB0033805; LS-191073; D4257; GSI-IX, 208255-80-5; X7572; W-5319; AB01566837_01; GSI-IX , GSI IX; 208255-80-5; N-[N-(3,5-difluorophenylacetyl)-L-alanyl]-(S)-phenylglycine t-butyl ester; DAPT|N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester; N-[(3,5-Difluorophenyl)acetyl]-[l-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester; N-[N-(3,5-difluorophenylacetyl)-L-alanyl]-(S)-phenylglycine t-butyl ester. Grades: 0.98. CAS No. 208255-80-5. Molecular formula: C23H26F2N2O4. Mole weight: 432.46.
Heptakis (2, 3-di-O-acetyl-6-O-tert-butyldimethylsilyl) cyclomaltoheptaose, a highly significant compound extensively utilized in the biomedical sector, assumes a pivotal role in diverse therapeutic applications. With its remarkable capacity to effectively combat numerous afflictions, this product stands out as an indispensable entity within the realm of modern biomedical research and development. Beneath its intricately designed structure lies a potent agent capable of precisely targeting specific medications or facilitating the development of innovative drug delivery systems. Synonyms: Silyl(6-O-tert-butyldimethyl)-2,3-di-acetyl)-b-cyclodextrin; Heptakis(6-O-tert-butyldimethylsilyl)-b-cyclodextrin tetradecaacetate. CAS No. 123172-94-1. Molecular formula: C112H196O49Si7. Mole weight: 2523.32.
Oxytocin acetate
Oxytocin acetate is a mammalian neurohypophysial hormone. Its actions are mediated by specific, high-affinity oxytocin receptors. Oxytocin is normally produced in the hypothalamus and stored in the posterior pituitary gland, which plays a role in intimacy, sexual reproduction of both sexes, and during and after childbirth. Synonyms: (S)-N-((S)-1-((2-amino-2-oxoethyl)amino)-4-methyl-1-oxopentan-2-yl)-1-((4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-((S)-sec-butyl)-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl)pyrrolidine-2-carboxamide acetate; Orasthin; Ossitocina; Ossitocina; Oxetakain; Oxitocina; Oxoject; Oxystin; Partocon; Pitocin; Piton S; Oxt,; Oxytocin. Grades: >98%. CAS No. 6233-83-6. Molecular formula: C45H70N12O14S2. Mole weight: 1067.24.
Ac-VEID-CHO is an inhibitor of caspase-6 (IC50 = 16.2 nM). It is selective for caspase-6 over caspase-7 (IC50 = 162.1 nM) but can also inhibit caspase-3 (IC50 = 13.6 nM). Synonyms: N-acetyl-L-valyl-L-alpha-glutamyl-L-isoleucyl-L-aspart-1-al; N-acetyl-Val-Glu-Ile-Asp-aldehyde; N-Acetyl-L-valyl-L-alpha-glutamyl-N-[(2S)-1-carboxy-3-oxo-2-propanyl]-L-isoleucinamide; L-Isoleucinamide, N-acetyl-L-valyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-; N-Acetyl-Val-Glu-Ile-Asp-al; (4S,7S,10S,13S)-10-((S)-sec-butyl)-7-(2-carboxyethyl)-13-formyl-4-isopropyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid; Caspase-6 Inhibitor; Ac-VEID-CHO. Grades: ≥95%. CAS No. 319494-39-8. Molecular formula: C22H36N4O9. Mole weight: 500.54.
Atosiban Impurity 1
Atosiban Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((4R,7S,10S,13S,16R)-4-((S)-2-(((S)-5-amino-1-((2-amino-2-oxoethyl)amino)-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carbonyl)-13-((S)-sec-butyl)-16-(4-ethoxybenzyl)-10-((R)-1-hydroxyethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-7-yl)acetic acid. Molecular Formula: C43H66N10O13S2. Mole Weight: 995.17. Catalog: APB03023.
Carfilzomib
Carfilzomib is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. Group: Biochemicals. Alternative Names: (α S) -α - [ [2- (4-Morpholinyl) acetyl] amino] benzenebutanoyl-L-leucyl-N- [ (1S) -3-methyl-1- [ [ (2R) -2-methyl-2-oxiranyl] carbonyl] butyl] -L-phenylalaninamide; (α S) -α - [ (4-Morpholinylacetyl) amino] benzenebutanoyl-L-leucyl-N- [ (1S) -3-methyl-1- [ [ (2R) -2-methyloxiranyl] carbonyl] butyl] -L-phenylalaninamide; PR 171. Grades: Highly Purified. CAS No. 868540-17-4. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C40H57N5O7, Molecular Weight: 719.91. US Biological Life Sciences.
Worldwide
Dihydrocephalomannine
Dihydrocephalomannine is one of Paclitaxel impurities. Paclitaxel is a tetracyclic diterpenoid isolated originally from the Pacific yew tree Taxus brevifolia. It is a mitotic inhibitor used in cancer chemotherapy. It has a role as a microtubule-stabilising agent, a metabolite, a human metabolite and an antineoplastic agent. Synonyms: 2'',3''-Dihydrocephalomannine; Benzenepropanoic acid, α-hydroxy-β-[(2-methyl-1-oxobutyl)amino]-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-; Benzenepropanoic acid, α-hydroxy-β-[(2-methyl-1-oxobutyl)amino]-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, [2aR-[2aα, 4β, 4aβ, 6β, 9α(αR*, βS*), 11α, 12α, 12aα, 12bα]]-; N-Debenzoyl-N-α-methylbutyrylpaclitaxel; Baccatin III 13-ester with (2R,3S)-2-hydroxy-3-(2-methylbutanoylamino)-3-phenylpropanoic acid; Paclitaxel sec-butyl analog. Grades: 95%. CAS No. 159001-25-9. Molecular formula: C45H55NO14. Mole weight: 833.91.
Methyl 2,3,4-tri-O-acetyl-6-O-tert-butyldimethylsilyl-a-D-galactopyranoside, a pivotal compound within the biomedicine sector, holds substantial significance. Leveraged extensively for creating pharmaceutical concoctions to combat myriad disorders, particularly those intricately entwined with carbohydrate metabolism, this exceptional product propels the advancement of therapeutic modalities against ailments such as diabetes, glycogen storage diseases, and select malignancies. CAS No. 594841-23-3. Molecular formula: C19H34O9Si. Mole weight: 434.56.
Methyl 2,3,4-tri-O-acetyl-6-O-tert-butyldiphenylsilyl-α-D-mannopyranoside is an extremely valuable compound within the biomedical sector, holds immense promise for diverse drug and molecular syntheses. It seamlessly assumes the role of an intermediary, instrumental in the creation of targeted compounds. Molecular formula: C29H38O9Si. Mole weight: 558.71.
N4-Acetyl-3'-O-tert-butyldimethylsilyl-cytidine 2'-CE phosphoramidite, an indispensable compound within the biomedical sector, assumes a pivotal function in the intricate fabrication of oligonucleotides for the purpose of conducting genetic inquiries and advancing therapeutic compounds. Of noteworthy significance, this remarkable product operates explicitly to induce alterations upon the cytidine base while engendering nucleic acid sequences, thereby facilitating precise countermeasures against an array of afflictions such as neoplastic proliferation, viral assault, and hereditary anomalies. Molecular formula: C47H64N5O9PSi. Mole weight: 902.10.
Tenuazonic Acid
An alternaria mycotoxin, found in common edible crops. It inhibits protein synthesis in fibroblasts. Group: Biochemicals. Alternative Names: L-3-Acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one; (5S)-3-Acetyl-1,5-dihydro-4-hydroxy-5-[(1S)-1-methylpropyl]-2H-pyrrol-2-one; AAC-toxin; L-Tenuazonic Acid. Grades: Highly Purified. CAS No. 610-88-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Tenuazonic acid Copper Salt
Tenuazonic Acid Copper Salt is an alternaria mycotoxin, found in common edible crops. It inhibits protein synthesis in fibroblasts. Synonyms: 3-Pyrrolin-2-one, 3-acetyl-5-sec-butyl-4-hydroxy-, L-, Copper Salt; L-3-Acetyl-5-sec-butyl-4-hydroxy-3-pyrrolin-2-one Copper Salt; (5S)-3-Acetyl-1,5-dihydro-4-hydroxy-5-[(1S)-1-methylpropyl]-2H-pyrrol-2-one Copper Salt; AAC-toxin Copper Salt; L-Tenuazonic Acid Copper Salt. Grades: ≥98%. CAS No. 12427-40-6. Molecular formula: C20H28CuN2O6. Mole weight: 455.99.
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