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Semaglutide is an agonist of glucagon-like peptide-1 (GLP-1) receptor that is developed to treat type 2 diabetes. It reduces blood sugar via increasing the production of insulin. On Oct 18, 2017, Novo Nordisk received positive 16-0 vote from FDA Advisory Committee in favor of approval for Semaglutide. Uses: The treatment of type 2 diabetes. Synonyms: L-Histidyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; BGM 134; NN 9535; NN 9536; NNC 0113-0217; Ozempic; Rybelsus; Wegovy; (3S, 9S, 12S, 15S, 18S, 21S, 24S, 27S, 30S, 33S, 36S, 39S, 45S, 48S, 51S, 54S, 81S)-54-(((6S, 12S, 15S, 18S, 21S, 24S, 27S, 30S, 33S)-21-(.. Grades: >98%. CAS No. 910463-68-2. Molecular formula: C187H291N45O59. Mole weight: 4113.64.
Semaglutide acetate
Semaglutide acetate, a long-acting GLP-1 analogue, is a glucagon-like peptide-1 (GLP-1) receptor agonist. Semaglutide acetate has the potential for type 2 diabetes treatment. Uses: Scientific research. Group: Peptides. CAS No. 1997361-85-9. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-114118B.
Semaglutide-[d15] is the labelled analogue of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide-d15; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val(D8)-Ser-Ser-Tyr-Leu(D7)-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C187H276D15N45O59. Mole weight: 4128.73.
Semaglutide, FITC labeled
Semaglutide, FITC labeled is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide, FITC labeled promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide, FITC labeled also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide, FITC labeled has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing ?-synuclein aggregation) and improving hepatic steatosis. Semaglutide, FITC labeled can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer[1][2][3][4][5]. Uses: Scientific research. Group: Peptides. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114118F.
Semaglutide Impurity 10
Semaglutide Impurity 10 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C188H291N45O61. Mole weight: 4157.65.
Semaglutide Impurity 11
Semaglutide Impurity 11 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C187H291N43O59. Mole weight: 4085.63.
Semaglutide Impurity 12
Semaglutide Impurity 12 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: 3,6-Dioxa-9,14-diazadotriacontanedioic acid, 13-[(1,1-dimethylethoxy)carbonyl]-10,15-dioxo-, 32-(1,1-dimethylethyl) ester, (13R)-; 32-(1,1-Dimethylethyl) (13R)-13-[(1,1-dimethylethoxy)carbonyl]-10,15-dioxo-3,6-dioxa-9,14-diazadotriacontanedioate. Molecular formula: C37H68N2O10. Mole weight: 700.96.
Semaglutide Impurity 13
Semaglutide Impurity 13 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: 3,6,12,15-Tetraoxa-9-azaheptadecan-1-oic acid, 17-[[(4R)-5-(1,1-dimethylethoxy)-4-[[18-(1,1-dimethylethoxy)-1,18-dioxooctadecyl]amino]-1,5-dioxopentyl]amino]-10-oxo-; (22R)-43,43-Dimethyl-22-{[(2-methyl-2-propanyl)oxy]carbonyl}-10,19,24,41-tetraoxo-3,6,12,15,42-pentaoxa-9,18,23-triazatetratetracontan-1-oic acid; 3,6,12,15-Tetraoxa-9,18,23-triazahentetracontanedioic acid, 22-[(1,1-dimethylethoxy)carbonyl]-10,19,24-trioxo-, 41-(1,1-dimethylethyl) ester, (22R)-; 41-(1,1-Dimethylethyl) (22R)-22-[(1,1-dimethylethoxy)carbonyl]-10,19,24-trioxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontanedioate. Molecular formula: C43H79N3O13. Mole weight: 846.11.
Semaglutide Impurity 14
Semaglutide Impurity 14 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C43H80N4O12. Mole weight: 845.13.
Semaglutide Impurity 15
Semaglutide Impurity 15 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C49H90N4O16. Mole weight: 991.27.
Semaglutide Impurity 16
Semaglutide Impurity 16 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Glycine, N-L-α-glutamyl-, 5-(1,1-dimethylethyl) ester; Glutaramic acid, 4-amino-N-(carboxymethyl)-, 1-tert-butyl ester, L-; (S)-(2-amino-5-(tert-butoxy)-5-oxopentanoyl)glycine; H-Glu(OtBu)-Gly-OH; ({(2S)-2-Amino-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoyl}amino)acetic acid. CAS No. 23406-82-8. Molecular formula: C11H20N2O5. Mole weight: 260.29.
Semaglutide Impurity 17
Semaglutide Impurity 17 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C23H33N3O8. Mole weight: 479.53.
Semaglutide Impurity 18
Semaglutide Impurity 18 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C15H27N3O6. Mole weight: 345.40.
Semaglutide Impurity 19
Semaglutide Impurity 19 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C46H58N6O9. Mole weight: 839.00.
Semaglutide Impurity 1 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: L-Histidyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-(L-tryptophyl-hydroxybenzyl)-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-(Trp-hydroxybenzyl)-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C194H297N45O60. Mole weight: 4219.77.
Semaglutide Impurity 2
Semaglutide Impurity 2 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Na-(((9H-fluoren-9-yl)methoxy)carbonyl)-1-(4-((tert-butyldiphenylsilyl)oxy)benzyl)-L-tryptophan. Molecular formula: C49H46N2O5Si. Mole weight: 771.00.
Semaglutide Impurity 20
Semaglutide Impurity 20 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C41H48N6O9. Mole weight: 768.87.
Semaglutide Impurity 21
Semaglutide Impurity 21 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. CAS No. 2377584-78-4. Molecular formula: C26H42N6O9. Mole weight: 582.66.
Semaglutide Impurity 22
Semaglutide Impurity 22 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C45H56N6O9. Mole weight: 824.98.
Semaglutide Impurity 23
Semaglutide Impurity 23 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C49H63N7O10. Mole weight: 910.08.
Semaglutide Impurity 3 (P3 Semaglutide)
Semaglutide Impurity 3 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C126H206N30O36. Mole weight: 2717.21.
Semaglutide Impurity 4 (U7 Semaglutide)
Semaglutide Impurity 4 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C29H51N5O14. Mole weight: 693.75.
Semaglutide Impurity 5 (U6 Semaglutide)
Semaglutide Impurity 5 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Molecular formula: C27H47N5O14. Mole weight: 665.69.
Semaglutide Impurity 6
Semaglutide Impurity 6 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: 3,6-Dioxa-9,14-diazadotriacontanedioic acid, 13-[(1,1-dimethylethoxy)carbonyl]-10,15-dioxo-, 32-(1,1-dimethylethyl) ester, (13S)-; 32-(1,1-Dimethylethyl) (13S)-13-[(1,1-dimethylethoxy)carbonyl]-10,15-dioxo-3,6-dioxa-9,14-diazadotriacontanedioate. CAS No. 1671100-14-3. Molecular formula: C37H68N2O10. Mole weight: 700.96.
Semaglutide Impurity 7
Semaglutide Impurity 7 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. It is also an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. Synonyms: 1-tert-Butyl 18-(2,5-dioxopyrrolidin-1-yl) octadecanedioate; Boc-C16-NHS ester; t-butyl-octadecanedioate-NHS ester; Succinimidyl tert-butyl octadecandioate; Octadecanedioic acid tert-butyl ester 2,5-dioxopyrrolidin-1-yl ester; Octadecanedioic acid, 1-(1,1-dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) ester; 1-(1,1-Dimethylethyl) 18-(2,5-dioxo-1-pyrrolidinyl) octadecanedioate; Octadecanoic acid, 18-[(2,5-dioxo-1-pyrrolidinyl)oxy]-18-oxo-, 1,1-dimethylethyl ester; 18-tert-Butoxy-18-oxooctadecanoic acid succinimidyl ester. CAS No. 843666-34-2. Molecular formula: C26H45NO6. Mole weight: 467.65.
Semaglutide Impurity 8
Semaglutide Impurity 8 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: L-Glutamic acid, N-[18-(1,1-dimethylethoxy)-1,18-dioxooctadecyl]-, 1-(1,1-dimethylethyl) 5-(2,5-dioxo-1-pyrrolidinyl) ester; 1-(1,1-Dimethylethyl) 5-(2,5-dioxo-1-pyrrolidinyl) N-[18-(1,1-dimethylethoxy)-1,18-dioxooctadecyl]-L-glutamate; (S) -2- (17-tert-Butoxycarbonylheptadecanoylamino) pentanedioic acid 1-tert-butyl ester 5-(2,5-dioxopyrrolidin-1-yl) ester; 5-(2,5-Dioxo-1-pyrrolidinyl) 1-(2-methyl-2-propanyl) N-{18-[(2-methyl-2-propanyl)oxy]-18-oxooctadecanoyl}-L-glutamate; N-[18-(1,1-Dimethylethoxy)-1,18-dioxooctadecyl]-L-glutamic acid 1-(1,1-dimethylethyl) 5-(2,5-dioxo-1-pyrrolidinyl) ester. Grades: ≥95%. CAS No. 1188328-22-4. Molecular formula: C35H60N2O9. Mole weight: 652.87.
Semaglutide Impurity 9
Semaglutide Impurity 9 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: L-2-oxo-Histidyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; (2-oxo-His)-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C187H289N45O60. Mole weight: 4127.62.
Semaglutide intermediate
Semaglutide intermediate is an intermediate of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: (S)-21,39-di-tert-butyl 1-(2,5-dioxopyrrolidin-1-yl) 9,18,23-trioxo-2,5,11,14-tetraoxa-8,17,22-triazanonatriacontane-1,21,39-tricarboxylate; 17- ( (S) -1-tert-Butoxycarbonyl-3-{2-[2- ({2-[2- (2, 5-dioxopyrrolidin-1-yloxycarbonylmethoxy) ethoxy]ethylcarbamoyl}methoxy) ethoxy]-ethylcarbamoyl}propylcarbamoyl) heptadecanoic acid tert-butyl ester; Octadecanoic acid, 18-[[(1S)-1-[(1,1-dimethylethoxy)carbonyl]-22-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4,13,22-trioxo-8,11,17,20-tetraoxa-5,14-diazadocos-1-yl]amino]-18-oxo-, 1,1-dimethylethyl ester; Bis(2-methyl-2-propanyl) (22S)-1-[(2,5-dioxo-1-pyrrolidinyl)oxy]-1,10,19,24-tetraoxo-3,6,12,15-tetraoxa-9,18,23-triazatetracontane-22,40-dicarboxylate; tBuO-Ste-Glu(AEEA-AEEA-OSu)-OtBu. Grades: ≥95%. CAS No. 1118767-15-9. Molecular formula: C47H82N4O15. Mole weight: 943.19.
Semaglutide intermediate P29
An intermediate of Semaglutide, an agonist of glucagon-like peptide-1 (GLP-1) receptor that is developed to treat type 2 diabetes. Synonyms: Semaglutide [sequence (9-37)]; L-α-Glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Grades: ≥95%. CAS No. 1169630-82-3. Molecular formula: C142H216N38O45. Mole weight: 3175.47.
Semaglutide-[Phe-d5]
Semaglutide-[Phe-d5] is the labelled analogue of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: H-His-Aib-Glu-Gly-Thr-Phe(D5)-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; Semaglutide D5; Semaglutide-d5. Molecular formula: C187H286D5N45O59. Mole weight: 4118.67.
Semaglutide-[Phe-d8]
Semaglutide-[Phe-d8] is the labelled analogue of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: H-His-Aib-Glu-Gly-Thr-Phe(D8)-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; Semaglutide D8; Semaglutide-d8. Molecular formula: C187H283D8N45O59. Mole weight: 4121.69.
Semaglutide related compound 1
Semaglutide related compound 1 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 1; Semaglutide Iso Asp Impurity; H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Iso-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C187H291N45O59. Mole weight: 4113.64.
Semaglutide related compound 10
Semaglutide related compound 10 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 10. Molecular formula: C190H295N47O61. Mole weight: 4213.72.
Semaglutide related compound 11
Semaglutide related compound 11 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 11. Molecular formula: C187H290N46O61. Mole weight: 4158.64.
Semaglutide related compound 12
Semaglutide related compound 12 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 12. Molecular formula: C188H290N46O61. Mole weight: 4170.65.
Semaglutide related compound 13
Semaglutide related compound 13 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 13. Molecular formula: C187H290N46O62. Mole weight: 4174.64.
Semaglutide related compound 14
Semaglutide related compound 14 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 14. Molecular formula: C189H294N46O60. Mole weight: 4170.69.
Semaglutide related compound 15
Semaglutide related compound 15 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 15. Molecular formula: C189H294N46O60. Mole weight: 4170.69.
Semaglutide related compound 16
Semaglutide related compound 16 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 16. Molecular formula: C189H294N46O60. Mole weight: 4170.69.
Semaglutide related compound 17
Semaglutide related compound 17 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 17. Molecular formula: C189H292N46O59. Mole weight: 4152.68.
Semaglutide related compound 18
Semaglutide related compound 18 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 18. Molecular formula: C186H288N46O58. Mole weight: 4096.61.
Semaglutide related compound 19
Semaglutide related compound 19 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 19. Molecular formula: C185H286N46O58. Mole weight: 4082.59.
Semaglutide related compound 2
Semaglutide related compound 2 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 2; H-His-Aib-Glu-Gly-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; Des-Thr(5)-Semaglutide; Semaglutide Des Thr-11 Impurity. Molecular formula: C183H284N44O57. Mole weight: 4012.54.
Semaglutide related compound 3
Semaglutide related compound 3 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 3; Semaglutide Plus 106 Impurity; H-D-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-(Trp-2-hydroxybenzyl)-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C194H297N45O60. Mole weight: 4219.77.
Semaglutide related compound 4
Semaglutide related compound 4 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 4; Semaglutide Endo Gly-10 Impurity; Endo-Gly(4)-Semaglutide; Endo-Gly(10)-Semaglutide; L-Histidyl-2-methylalanyl-L-α-glutamylglycylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-His-Aib-Glu-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C189H294N46O60. Mole weight: 4170.69.
Semaglutide related compound 6
Semaglutide related compound 6 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 6; Semaglutide D-His-7 Impurity; D-His(7)-Semaglutide; D-His(1)-Semaglutide; D-Histidyl-2-methylalanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-D-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH. Molecular formula: C187H291N45O59. Mole weight: 4113.64.
Semaglutide related compound 8
Semaglutide related compound 8 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 8. Molecular formula: C188H292N46O60. Mole weight: 4156.67.
Semaglutide related compound 9
Semaglutide related compound 9 is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide SZ Impurity 9. Molecular formula: C190H295N47O61. Mole weight: 4213.72.
Semaglutide TFA
Semaglutide TFA is a long-acting, selective, competitive GLP-1R agonist that can penetrate the blood-brain barrier. After activating GLP-1R, Semaglutide TFA promotes insulin secretion, inhibits gastric emptying and appetite, and at the same time enhances autophagy, inhibits oxidative stress and apoptosis. Semaglutide TFA also regulates mitochondrial function and lipid metabolism (such as reducing de novo lipogenesis in the liver). Semaglutide TFA has activities such as lowering blood sugar, reducing weight, neuroprotection (such as improving motor function in Parkinson's disease models, reducing ?-synuclein aggregation) and improving hepatic steatosis. Semaglutide TFA can be used for the study of neurodegenerative diseases and liver diseases such as type 2 diabetes, obesity, Parkinson's disease, metabolic associated fatty liver disease (MASLD), and cancer[1][2][3][4][5]. Uses: Scientific research. Group: Peptides. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-114118A.
Semaglutide-[Val-d8] Tetratrifluoroacetate
Semaglutide-[Val-d8] Tetratrifluoroacetate is the labelled salt of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: Semaglutide-d8 Tetratrifluoroacetate; L-histidyl-2-methylalanyl-L-a-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-a-aspartyl-L-valyl-d8-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-a-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-a-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-a-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginyl-Glycine, trifluoroacetic acid (1:4); H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val(D8)-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH.4TFA. Molecular formula: C187H283D8N45O59.4C2HF3O2. Mole weight: 4577.78.
Des-Glu(3)-Semaglutide
Des-Glu(3)-Semaglutide is an impurity of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes. Synonyms: L-Histidyl-2-methylalanylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-[N-(17-carboxy-1-oxoheptadecyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginylglycine; H-His-Aib-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH; Des-Glu(9)-Semaglutide. Molecular formula: C182H284N44O56. Mole weight: 3984.53.
Des-Gly (10)-Semaglutide
Des-His(7)-Semaglutide
D-Ser(14)-Semaglutide
Fmoc-His-Aib-OH TFA
An intermediate in the synthesis of Semaglutide, an agonist of glucagon-like peptide-1 (GLP-1) receptor that is developed to treat type 2 diabetes. Grades: ≥98%. CAS No. 1446013-08-6. Molecular formula: C25H26N4O5.C2HF3O2. Mole weight: 576.53.
Fmoc-L-Lys(Boc-AEEA)-OH
Used as a linker in solid-phase peptide synthesis and in Semaglutide preparation. Synonyms: Nα -Fmoc-Nε - (2- (2- (2- (tert-butyloxycarbonyl) aminoethoxy) ethoxy) acetyl) -L-lysine; Nα-Fmoc-Nε-(AEEA-Boc)-L-Lysine. Grades: ≥ 99% (Assay by titration, HPLC). CAS No. 1662688-16-5. Molecular formula: C32H43N3O9. Mole weight: 613.70.
Octa(OtBu)-Glu-OtBu
An intermediate in the synthesis of Semaglutide, an agonist of glucagon-like peptide-1 (GLP-1) receptor that is developed to treat type 2 diabetes. Synonyms: L-Glutamic acid, N-[18-(1,1-dimethylethoxy)-1,18-dioxooctadecyl]-, 1-(1,1-dimethylethyl) ester. CAS No. 1188328-39-3. Molecular formula: C31H57NO7. Mole weight: 555.79.
SHR-2042 is a novel glucagon-like peptide-1 recceptor agonist (GLP-1RA) with higher oral bioavailability. The oral bioavailability of SHR-2042 matched with SNAC is 3.39% (1:30, w/w) in monkeys, which is over 10 times higher than that of semaglutide. Synonyms: SHR 2042; SHR2042.
tBuO-Ste-Glu(AEEA-AEEA-OH)-OtBu
A 18-carbon fatty acid side chain of semaglutide. The affinity of the semaglutide side chain for albumin was enhanced 5-6 times. Semaglutide is a glucagon-like peptide-1 (GLP-1) analog with significant hypoglycemic efficacy. Synonyms: Semaglutide Side Chain; Fmoc-L-Lys[OctotBu)-Glu-(otBu)-AEEA-AEEA]-OHu; (S)-22-(Tert-butoxycarbonyl)-10,19,24-trioxo-3,6,12,15-tetraoxa-9,18,23-triazahentetracontane-1,41-dioic acid; (S)-22-(tert-butoxycarbonyl)-43,43-dimethyl-10,19,24,41-tetraoxo-3,6,12,15,42-pentaoxa-9,18,23-triazatetratetracontanoic acid. Grades: ≥98%. CAS No. 1118767-16-0. Molecular formula: C43H79N3O13. Mole weight: 846.11.
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