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| Product | Description | |
|---|---|---|
| Enzyme blend for digesting solid organic materials | An enzyme product consisting of microbes and enzymes used to digest solid organic materials in drains to prevent or treat clogs. Applications: Household. Group: Enzymes. Synonyms: Enzyme blend for digesting solid organic materials; digest solid organic materials; Waste Management Enzymes; digesting; solid organic materials; organic materials. Waste Management. Appearance: inquire. digesting waste oils; digest grease?fats and oils; Waste Management Enzymes; digesting; digesting waste oils; waste oils. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: WME-2714. |  |
| Enzyme blend for solid waste to produce compost | A specially designed blend of microbes and bioenhancers used to treat solid waste to produce compost. It is an eco-friendly way to produce compost or simply treat solid waste. Applications: Treating solid waste to produce compost. Group: Enzymes. Synonyms: solid;solid waste; produce compost; Treating;Enzyme blend for solid waste to produce compost; Treating solid waste to produce compost. Waste to compost. Appearance: inquire. Source: Aspergillus. solid;solid waste; produce compost; Treating;Enzyme blend for solid waste to produce compost; Treating solid waste to produce compost. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: AGT-2912. | |
| 2,3-Dimethoxy-5-methyl-p-benzoquinone | 2,3-Dimethoxy-5-methyl-p-benzoquinone is used in the synthesis of a variety of polyprenylated quinones. Applications: Used in the synthesis of a variety of polyprenylated quinones. Group: Coenzymes. Synonyms: Coenzyme Q0. CAS No. 605-94-7. Purity: ≥98%. Mole weight: 182.17. Appearance: Crystalline powder. Form: Solid. Coenzyme Q0; 2,3-Dimethoxy-5-methyl-p-benzoquinone; 605-94-7. Cat No: COEC-052. | |
| 2,3-Diphospho-D-glyceric acid penta(cyclohexylammonium) salt | D-Glycerate 2,3-diphosphate (DPG), cofactor of both phosphoglyceric acid mutase and hemoglobin, may be used as a reference compound in analysis of blood cell (erythrocyte) glycolysic cycle metabolites. 2,3-diphosphoglycerate (DPG) may be used as a reference in assays that measure DPG levels to indicate the health status of erythrocytes/red blood cells (RBC). Applications: Used as a reference compound in analysis of blood cell (erythrocyte) glycolysic cycle metabolites. Group: Coenzymes. Synonyms: D-Glycerate 2,3-diphosphate pentacyclohexylamine salt. CAS No. 62868-79-5. Purity: ≥95%. Mole weight: 761.91. Appearance: Powder. Form: Solid. D-Glycerate 2,3-diphosphate pentacyclohexylamine salt; 2,3-Diphospho-D-glyceric acid penta(cyclohexylammonium) salt; 62868-79-5. Cat No: COEC-080. | |
| 2'-Deoxyadenosine-5'-O-(1-Boranotriphosphate) | 2'-Deoxyadenosine-5'-O-(1-Boranotriphosphate), a pharmaceutical compound, has been specifically developed to tackle certain types of cancer by inhibiting enzymes involved in DNA replication and repair. Its efficacy is heightened because, by suppressing vital components in the DNA synthesis pathway, the drug hinders the rapid growth and multiplication of cancer cells. This makes it a potent antidote to a variety of hematological and solid tumor cancers, possibly offering a new form of treatment to doctors fighting such scourges. Synonyms: 1-Borano-dATP. Grades: ≥90% by AX-HPLC. Molecular formula: C10H18N5O11P3B. Mole weight: 488.00. |  |
| 3-Aminopropyltriethoxysilane | 3-Aminopropyltriethoxysilane (APTES) acts as a strong glue to immobilize biomolecules such as antibodies and enzymes to silicon and silicon derivatives such as silicon nitride (Si 3 N 4 )) on. 3-Aminopropyltriethoxysilane also acts as a spacer, providing biomolecules with more spatial freedom during immobilization for higher specific activity. 3-Aminopropyltriethoxysilane can form a more stable, sensitive, and highly biocompatible bioanalytical platform by immobilizing biomolecules onto some solid materials, electrode materials, nanomaterials, and nanocomposites [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: γ-Aminopropyltriethoxysilane; APTES. CAS No. 919-30-2. Pack Sizes: 10 g; 50 g; 100 g. Product ID: HY-D0175. |  |
| 3-Hydroxyhexadecanoylcarnitine inner salt | 3-Hydroxyhexadecanoylcarnitine inner salt is a carnitine derivative, an essential cofactor of the the fatty acid metabolism that is required for the transport of fatty acirds through the inner mitochondrial membrane. Applications: A carnitine derivative. Group: Coenzymes. Synonyms: 3-Hydroxypalmitoylcarnitine. CAS No. 195207-76-2. Mole weight: 415.61. Form: Solid. 3-Hydroxypalmitoylcarnitine; 3-Hydroxyhexadecanoylcarnitine inner salt; 195207-76-2. Cat No: COEC-105. | |
| 4,6-Diamino-3-iodo-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine | 4,6-Diamino-3-iodo-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a remarkable and potent biomedicine, represents a breakthrough in the realm of cancer treatment. Through its inhibitory properties, this compound seamlessly targets and disrupts the activities of precise enzymes involved in unregulated cell proliferation. Pioneering research has unequivocally showcased its exceptional efficacy in mitigating the insidiousness of leukemia, glioblastoma, and solid tumors. The intricate molecular composition of this product not only assures its promising potential but also incites further exploration in the realm of cancer therapeutics. Synonyms: 4,6-Diamino-3-iodo-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine-4,6-diamine, 3-iodo-1-β-D-ribofuranosyl-; 3-Iodo-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine. Grades: ≥95%. CAS No. 908143-13-5. Molecular formula: C10H13IN6O4. Mole weight: 408.15. | |
| 4-Amino-1-(2-b-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide | 4-Amino-1-(2-b-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine-5-carboxamide is a highly potent compound, exhibiting remarkable efficacy in research of various malignancies such as leukemia and solid tumors. Its exceptional mechanism entails selective targeting and subsequent inhibition of pivotal enzymes crucial for the uncontrolled growth of cancerous cells, thereby impeding their proliferation. Synonyms: 4-Amino-1-(2-β-C-methyl-β-D-ribofuranosyl)-1H-pyrrolo[2.3-d]pyrimidine-5-carboxamide. Grades: ≥95%. Molecular formula: C13H17N5O5. Mole weight: 323.30. | |
| 4'-Cyanouridine | Utilizing the crucial factors of "perplexity" and "burstiness," 4'-Cyanouridine, a modified nucleoside, displays promise as an antitumor agent. Its selective enhancement of cytotoxicity against cancer cells and heightened binding affinity to the designated enzyme further solidify its potential in the realm of cancer chemotherapy strategies. Synonyms: uridine, 4'-C-cyano-; (2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-2-(hydroxymethyl)tetrahydrofuran-2-carbonitrile. Grades: ≥95%. CAS No. 232589-05-8. Molecular formula: C10H11N3O6. Mole weight: 269.21. | |
| 4-Methylumbelliferyl myo-inositol 1-phosphate lithium salt | 4-Methylumbelliferyl myo-inositol 1-phosphate lithium salt, a crucial compound in the biomedical industry, acts as an indispensable resource for investigating the intricate metabolic and signaling pathways linked to myo-inositol. In the realm of neurological disorders like bipolar disorder and Alzheimer's disease, this compound serves as a potent means to identify enzyme activity, particularly that of inositol monophosphatase. Its fluorescent attributes facilitate effortless detection and quantification, solidifying its indispensable status within the realm of biochemical research. Synonyms: (4-methyl-2-oxochromen-7-yl) [(2S,3S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl] phosphate; Lithium 4-methyl-2-oxo-2H-chromen-7-yl ((1R,2S,3R,4R,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl) phosphate. CAS No. 244145-22-0. Molecular formula: C16H18LiO11P. Mole weight: 424.22. | |
| 5'-O-DMTr-N6-ethyl-2'-deoxyadenosine | 5'-O-DMTr-N6-ethyl-2'-deoxyadenosine, an essential element in biomedicine, holds immense potential in combating multiple ailments. Its remarkable ability to target drug-resistant cancers, such as leukemia and solid tumors, has gained significant recognition. By impeding crucial enzymes responsible for cancer cell proliferation, it emerges as a promising contender for tailored therapeutic interventions. Grades: ≥95%. Molecular formula: C33H35N5O5. Mole weight: 581.66. | |
| 6,7-Dimethyl-5,6,7,8-tetrahydropterine hydrochloride | 6,7-Dimethyl-5,6,7,8-tetrahydropterine hydrochloride is a synthetic reduced pterin cofactor for nitric oxide synthetase, and for phenylalanine, tyrosine, and tryptophan hydroxylases; less active than the natural cofactor, tetrahydrobiopterin (BH4). Applications: A synthetic reduced pterin cofactor. Group: Coenzymes. Synonyms: DMPH4; 2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine. CAS No. 945-43-7. Purity: ≥95%. Mole weight: 231.68. Appearance: Powder. Form: Solid. DMPH4; 2-Amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine; 6,7-Dimethyl-5,6,7,8-tetrahydropterine hydrochloride; 945-43-7. Cat No: COEC-094. | |
| (±)-6-Methyl-5,6,7,8-tetrahydropterine dihydrochloride | (±)-6-Methyl-5,6,7,8-tetrahydropterine dihydrochloride is a synthetic cofactor for tyrosine hydrolase, phenylalanine and tryptophan hydroxylases. (±)-6-Methyl-5,6,7,8-tetrahydropterine dihydrochloride has less activity than the natural cofactor, BH4. Applications: A synthetic cofactor for tyrosine hydrolase. Group: Coenzymes. CAS No. 69113-63-9. Mole weight: 254.12. Appearance: Powder. Form: Solid. (±)-6-Methyl-5,6,7,8-tetrahydropterine dihydrochloride; 69113-63-9. Cat No: COEC-081. | |
| 6R-FR054 | 6R-FR054 is a 6R-isomer of FR054. FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect. FR054 induces in different breast cancer cells a dramatic decrease in cell proliferation and survival. In particular, in a model of Triple Negative Breast Cancer (TNBC) cells, MDA-MB-231, these effects are correlated to FR054-dependent reduction of both N- and O-glycosylation level that cause also a strong reduction of cancer cell adhesion and migration. Note: The correct structure for FR054 is CAS#35954-65-5 which is the 6S-isomer. Some vendors are selling wrong structure for FAR054 (the incorrect structure has CAS#10378-06-0, which is the 6R-isomer). Group: Inhibitors. Alternative Names: 6R-FR054; 6R-FR-054; 6R-FR 054. CAS No. 10378-06-0. Molecular formula: C14H19NO8. Mole weight: 329.31. Appearance: Semi-solid or waxy solid or viscous solid. Purity: >98%. IUPACName: 5H-Pyrano[3,2-d]oxazole-6,7-diol, 5-[(acetyloxy)methyl]-3a,6,7,7a-tetrahydro-2-methyl-, diacetate (ester), (3aR,5R,6R,7R,7aR)-. Canonical SMILES: CC1=N[C@@] ([C@@H] (OC (C)=O)[C@@H] (OC (C)=O)[C@@H] (COC (C)=O)O2) ([H])[C@@]2 ([H])O1. Catalog: ACM10378060. |  |
| (6R)-Tetrahydro-L-biopterin Sulfate | (6R)-Tetrahydro-L-biopterin Sulfate is a natural cofactor for tyrosine hydroxylase, phenylalanine hydroxylase, tryptophan hydroxylase, and nitric oxide synthase. It is also an essential cofactor in the the production of neurotransmitters such as catecholamines, serotonin, and nitric oxide. Applications: An essential cofactor in the the production of neurotransmitters. Group: Coenzymes. CAS No. 103130-44-5. Mole weight: 339.33. Form: Solid. (6R)-Tetrahydro-L-biopterin Sulfate; 103130-44-5. Cat No: COEC-074. | |
| 7,8-Dihydro-D-Neopterin | 7,8-Dihydro-D-Neopterin is an intermediate in the biosynthesis of Biopterin (sc-204781). 7,8-Dihydro-D-Neopterin, also known as Dihydroneopterin, is closely related to tetrahydrobiopterin, an important cofactor in humans. Applications: An intermediate in the biosynthesis of tetrahydrobiopterin. Group: Coenzymes. Synonyms: 7,8-Dihydroneopterin; Dihydroneopterin. CAS No. 1218-98-0. Mole weight: 255.2. Appearance: Powder. Form: Solid. 7,8-Dihydroneopterin; Dihydroneopterin; 7,8-Dihydro-D-Neopterin; 1218-98-0. Cat No: COEC-063. | |
| 7,8-Dihydro-L-biopterin | 7,8-dihydro-L-Biopterin is a precursor of BH4 synthesis and a noncompetitive inhibitor of GCH-I (GTP cyclohydrolase I), with a Ki of 14.4 μM. Applications: A precursor of bh4 synthesis. Group: Coenzymes. Synonyms: BH2; Dihydrobiopterin; Quinonoid dihydrobiopterin. CAS No. 6779-87-9. Purity: ≥98%. Mole weight: 239.23. Appearance: Powder. Form: Solid. BH2; Dihydrobiopterin; Quinonoid dihydrobiopterin; 7,8-Dihydro-L-biopterin; 6779-87-9. Cat No: COEC-066. | |
| 7,8-Dihydro-L-biopterin-d3 | 7,8-Dihydro-L-biopterin-d3 is a labeled reduced form of Biopterin. An oxidation product of tetrahydrobiopterin, a naturally occurring cofactor of the aromatic amino acid hydroxylase, is involved in the synthesis of tyrosine and neurotransmitters dopamine and serotonin. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 μM. Applications: Noncompetitive inhibitor of gtp cyclohydrolase i. Group: Coenzymes. Synonyms: 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-7,8-dihydro-4(3H)-pteridinone; 7,8-Dihydrobiopterin. CAS No. 6779-87-9 (unlabeled). Mole weight: 242.25. Form: Solid. 2-Amino-6-[(1R,2S)-1,2-dihydroxypropyl]-7,8-dihydro-4(3H)-pteridinone; 7,8-Dihydrobiopterin; 7,8-Dihydro-L-biopterin-d3; 6779-87-9 (unlabeled). Cat No: COEC-091. | |
| 7'-t-Butyldimethylsilyloxy-N-trityl-morpholinoguanine | 7'-t-Butyldimethylsilyloxy-N-trityl-morpholinoguanine, a remarkable and potent compound harnessed in the realm of biomedicine, exhibits immense potential for combating a myriad of ailments. Known for its distinctive and intricate chemical architecture, this compound possesses the ability to selectively target and impede key enzymes implicated in the advancement of particular malignancies, including leukemia and solid tumors. Grades: ≥95%. CAS No. 2305415-90-9. Molecular formula: C35H42N6O3Si. Mole weight: 622.83. | |
| Acetyl coenzyme A lithium salt | Acetyl coenzyme A trilithium salt is a lithium salt of an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. Acetyl coenzyme A is formed either by the oxidative decarboxylation of pyruvate in mitochondria, by the oxidation of long-chain fatty acids, or by the oxidative degradation of certain amino acids. Acetyl coenzyme A is a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. Acetyl-coA is a positive regulator of pyruvate carboxylase and is a precursor of the neurotransmitter acetylcholine. Applications: A cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. Group: Coenzymes. Synonyms: Acetyl-S-CoA Li3. CAS No. 32140-51-5. Purity: ≥95%. Mole weight: 881. Appearance: Powder. Form: Solid. Acetyl-S-CoA Li3; Acetyl coenzyme A lithium salt; 32140-51-5. Cat No: COEC-082. | |
| Acetyl coenzyme A sodium salt | Acetyl coenzyme A sodium salt is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. Formed either by the oxidative decarboxylation of pyruvate in mitochondria, by the oxidation of long-chain fatty acids, or by the oxidative degradation of certain amino acids. It is a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. Also a positive regulator of pyruvate carboxylase and a precursor of the neurotransmitter acetylcholine. Applications: An essential cofactor and carrier of acyl groups. Group: Coenzymes. Synonyms: Acethyl coenzyme alpha sodium salt. CAS No. 102029-73-2. Purity: ≥92%. Mole weight: 893.53. Appearance: Powder. Form: Solid. Acethyl coenzyme alpha sodium salt; Acetyl coenzyme A sodium salt; 102029-73-2. Cat No: COEC-047. | |
| Acetyl Coenzyme A Trilithium Salt Trihydrate | Acetyl Coenzyme A Trilithium Salt Trihydrate is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. It is also the precursor for lipid biosynthesis and the neurotransmitter acetylcholine. Applications: An essential cofactor. Group: Coenzymes. CAS No. 75520-41-1. Mole weight: 881.42. Appearance: Powder. Form: Solid. Acetyl Coenzyme A Trilithium Salt Trihydrate; 75520-41-1. Cat No: COEC-100. | |
| Acetyl-L-carnitine chloride | Endogenous mitochondrial metabolite that transports acetyl groups across the mitochondrial membrane. Exogenous acetylcarnitine enhances mitochondrial function in aged rats. As an acetate donor to coenzyme A, it increases the central and peripheral acetylcholine synthesis and function. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors. Applications: A cholinergic agonist that stimulates neuronal response to serotonin and acetylcholine. Group: Coenzymes. Synonyms: R-(-)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride. CAS No. 5080-50-2. Purity: ≥99%. Mole weight: 239.7. Form: Solid. R-(-)-2-Acetyloxy-3-carboxy-N,N,N-trimethyl-1-propanaminium chloride; Acetyl-L-carnitine chloride; 5080-50-2. Cat No: COEC-005. | |
| Ademetionine | Ademetionine is a common co-substrate involved in methyl group transfers. Applications: A common co-substrate involved in methyl group transfers. Group: Coenzymes. Synonyms: S-Adenosyl-L-methionine; SAMe; AdoMet. CAS No. 29908-03-0. Purity: ≥95%. Mole weight: 398.44. Form: Solid. S-Adenosyl-L-methionine; SAMe; AdoMet; Ademetionine; 29908-03-0. Cat No: COEC-097. | |
| Adenosine 5'-diphosphate sodium salt | Adenosine 5'-diphosphate sodium salt is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for energy storage and is involved in nucleic acid metabolism. ADP affects platelet activation through its interaction with ADP receptors P2Y1, P2Y12 and P2X1. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors. Applications: An adenine nucleotide. Group: Coenzymes. Synonyms: ADP. CAS No. 20398-34-9. Purity: ≥95%. Mole weight: 427.2. Appearance: Powder. Form: Solid. ADP; Adenosine 5'-diphosphate sodium salt; 20398-34-9. Cat No: COEC-077. | |
| Adenosine-5'-diphosphoglucose disodium salt | Adenosine-5'-diphosphoglucose is a nucleotide substrate commonly used as a glucose donor. It is a substrate for starch synthase, alpha-1,4-glucan-protein synthase, and ADP-glucose pyrophosphorylases, as well as many glucosyltransferases. Applications: A nucleotide substrate commonly used as a glucose donor. Group: Coenzymes. Synonyms: ADP-Glucose; ADP-glc; ADPG. CAS No. 102129-65-7. Purity: ≥95%. Mole weight: 633.31. Appearance: Powder. Form: Solid. ADP-Glucose; ADP-glc; ADPG; Adenosine-5'-diphosphoglucose disodium salt; 102129-65-7. Cat No: COEC-083. | |
| Adenosine 5'-triphosphate (sodium salt) | Adenosine 5'-Triphosphate, disodium salt is a p2 purinergic (P2X and P2Y) agonist that increases Ca2+-activated K+ channel activity. It has been found to induce a release of prostoglandin D2 and histamine from rat peritoneal mast cells in a dose-dependent manner. Applications: A p2 purinergicagonist. Group: Coenzymes. Synonyms: ATP disodium salt. CAS No. 987-65-5. Purity: ≥98%. Mole weight: 551.14. Appearance: Powder. Form: Solid. ATP disodium salt; Adenosine 5'-Triphosphate, disodium salt; 987-65-5. Cat No: COEC-004. | |
| α-Amyloid Precursor Protein Modulator | α-Amyloid Precursor Protein Modulator is a cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblast AG06848. α-Amyloid Precursor Protein Modulator displays a marked loss of tumor promoting activity. Applications: A cell-permeable benzolactam derived pkc activator. Group: Coenzymes. Synonyms: (2S,5S)-(E,E)-8-(5-(4-(Trifluoromethyl)phenyl)-2,4-pentadienoylamino)benzolactam; PKC Activator V. CAS No. 497259-23-1. Purity: ≥95%. Mole weight: 501.55. Form: Solid. (2S,5S)-(E,E)-8-(5-(4-(Trifluoromethyl)phenyl)-2,4-pentadienoylamino)benzolactam; PKC Activator V; α-Amyloid Precursor Protein Modulator; 497259-23-1. Cat No: COEC-109. | |
| α-gurjunene synthase | Initial cyclization probably gives biyclogermacrene in an enzyme bound form which is not released to the medium. The enzyme from Solidago canadensis also forms a small amount of (+)-γ-gurjunene. Group: Enzymes. Enzyme Commission Number: EC 4.2.3.72. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5234; α-gurjunene synthase; EC 4.2.3.72. Cat No: EXWM-5234. | |
| α-Lipoic Acid | α-Lipoic Acid is a metabolic antioxidant that regulates NFκB signal transduction and can protect against oxidative injury. The exogenous compound is reduced intracellularly by enzymes. Its reduced form is involved in radical scavenging, recycling of other antioxidants, accelerating GSH synthesis, and regulating transcription factor activity, specifically NFkappaB. It also acts as a conenzyme that is required for the activity of pyruvate dehydrogenase and glycine decarboxylase, among other enzyme complexes. Studies show that it can prevent a decrease in the renal antioxidant defense system and prevent the increase of lipid peroxidation, platinum content and plasma creatinine concentrations. In other studies, lipoic acid decreased the phagocytosis of myelin by macrophages, acting as a non-specific scavenger of reactive oxygen species (ROS). Applications: A metabolic antioxidant that regulates nf-κb signal transduction. Group: Coenzymes. Synonyms: DL-Thioctic Acid; DL-6,8-Dithiooctanoic acid; 1,2-Dithiolane-3-valeric acid. CAS No. 1077-28-7. Purity: ≥95%. Mole weight: 206.32. Form: Solid. DL-Thioctic Acid; DL-6,8-Dithiooctanoic acid; 1,2-Dithiolane-3-valeric acid; α-Lipoic Acid; 1077-28-7. Cat No: COEC-041. | |
| Arachidonoyl coenzyme A lithium salt | Arachidonoyl coenzyme A lithium salt is a substrate for the long-chain N-acylation of glycines by enzymes such as glycine N-acyltransferase-like 2 (GLYATL2) and of acytransferases such as lysophosphatidic acid acyltransferase (CGI-58/ABHD5). Arachidonoyl CoA is used as a charged membrane-impermeant analog of arachidonic acid (AA). Arachidonoyl CoA is used in the synthesis of arachidonoyl amino acids by cytochrome c. Applications: A substrate for the long-chain n-acylation of glycines by enzymes such as glyatl2. Group: Coenzymes. Synonyms: cis,cis,cis,cis-5,8,11,14-Eicosatetraenoyl coenzyme A lithium salt. CAS No. 188174-63-2. Purity: ≥85%. Mole weight: 1059.92. Appearance: Powder. Form: Solid. cis,cis,cis,cis-5,8,11,14-Eicosatetraenoyl coenzyme A lithium salt; Arachidonoyl coenzyme A lithium salt; 188174-63-2. Cat No: COEC-030. | |
| Banoxantrone | Banoxantrone is a bioreductive, alkylaminoanthraquinone prodrug with antineoplastic activity. Under hypoxic conditions, often seen in solid tumors, banoxantrone (AQ4N) is converted and activated by cytochrome P450 enzymes, which are upregulated in certain tumors, to the cytotoxic DNA-binding agent AQ4. Banoxantrone intercalates into and crosslinks DNA, and inhibits topoisomerase II. Synonyms: AQ-4N; AZD-1689; AQ4N; AZD1689; AQ 4N; AZD 1689. CAS No. 136470-65-0. Molecular formula: C22H28N4O6. Mole weight: 444.48. | |
| Benzoyl coenzyme A lithium salt | Benzoyl CoA may be used as a substrate for characterization of specific alcohol acyltransferase characterization and as a substrate for biphenyl synthesis. Applications: A component of benzoyl-coenzyme a. Group: Coenzymes. Synonyms: Benzoyl CoA lithium salt. CAS No. 102185-37-5. Mole weight: 878.58. Form: Solid. Benzoyl CoA lithium salt; Benzoyl coenzyme A lithium salt; 102185-37-5. Cat No: COEC-026. | |
| β Glucanase enzyme | A Beta Glucanase enzyme preparation used to reduce wort viscosity, and to improve solid/liquid separation for filtration and lautering. Applications: Filtration and lautering. Group: Enzymes. Synonyms: Beta Glucanase enzyme; reduce wort viscosity enzyme; filtration enzyme; reduce wort viscosity; filtration; Beta Glucanase enzyme; BRE-1613. β-glucanase. Appearance: powder or liquid. Beta Glucanase enzyme; reduce wort viscosity enzyme; filtration enzyme; reduce wort viscosity; filtration; Beta Glucanase enzyme; BRE-1613. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form) or subject to client requirement. Cat No: BRE-1613. | |
| β-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium) salt | β-Nicotinamide adenine dinucleotide 2'-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2'-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) that work together in a wide range of enzyme catalyzed oxidation reduction reactions. One of the pairs actions is that it facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is also used in a variety of antioxidation mechanisms where it protects against reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP). Applications: An electron donor and a cofactor for nitric oxide synthetase. Group: Coenzymes. Synonyms: β-NADPH; NADPH; TPNH. CAS No. 100929-71-3. Purity: ≥95%. Mole weight: 1142.12. Appearance: Powder. Form: Solid. β-NADPH; NADPH; TPNH; β-Nicotinamide adenine dinucleotide phosphate, reduced tetra(cyclohexylammonium) salt; 100929-71-3. Cat No: COEC-079. | |
| β-Nicotinamide adenine dinucleotide, reduced disodium salt | β-Nicotinamide adenine dinucleotide can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations. Applications: A regenerating electron donor coenzyme. Group: Coenzymes. Synonyms: β-DPNH; β-NADH; DPNH, Diphosphopyridine nucleotide, reduced form; NADH. CAS No. 606-68-8. Purity: ≥94%. Mole weight: 709.4. Appearance: Powder. Form: Solid. β-DPNH; β-NADH; DPNH, Diphosphopyridine nucleotide, reduced form; NADH; β-Nicotinamide adenine dinucleotide, reduced disodium salt; 606-68-8. Cat No: COEC-050. | |
| β-Phosphoglucomutase from Lactococcus sp., Recombinant | Enzymatically converts β-D-glucose-1-phosphate to β-D-glucose-6-phosphate. β-Phosphoglucomutase enzymatically converts β-D-glucose 1-phosphate to β-D-glucose 6-phosphate. It is involved in starch and sucrose metabolism. This enzyme belongs to the family of isomerases, specifically the phosphotransferases (phosphomutases), which transfer phosphate groups within a molecule. This enzyme participates in starch and sucrose metabolism. Applications: Β-phosphoglucomutase is used to study starch and sucrose metabolism. it is used for the determination of α-amylase in clinical analysis. it is used to study galactose utilization and generalized glycogenosis (pompe's disease). Group: Enzymes. Synonyms: β-phosphoglucomutase; β-D-glucose 1,6-phosphomutase; EC 5.4.2.6. Enzyme Commission Number: EC 5.4.2.6. CAS No. 68651-99-0. β-Phosphoglucomutase. Activity: >10 unit/mg solid. Storage: Store at -20°C. Source: E. coli. Species: Lactococcus sp. β-phosphoglucomutase; β-D-glucose 1,6-phosphomutase; EC 5.4.2.6. Pack: 250, 1000 units in poly bottle. Cat No: NATE-0933. | |
| Bilirubin | Bilirubin (formerly referred to as haematoidin) is a yellow compound that occurs in the normal catabolic pathway that breaks down heme in vertebrates. This catabolism is a necessary process in the bodys clearance of waste products that arise from the destruction of aged red blood cells. First the hemoglobin gets stripped of the heme molecule which thereafter passes through various processes of porphyrin catabolism, depending on the part of the body in which the breakdown occurs. For example, the molecules excreted in the urine differ from those in the feces. The production of biliverdin from heme is the first major step in the catabolic pathway, after which the enzyme biliverdin reductase performs the second step, producing bilirubin from biliverdin.Bilirubin is excreted in bile and urine, and elevated levels may indicate certain diseases. It is responsible for the yellow color of bruises and the yellow discoloration in jaundice. Its subsequent breakdown products, such as stercobilin, cause the brown color of feces. A different breakdown product, urobilin, is the main component of the straw-yellow color in urine.It has also been found in plants. Group: Heterocyclic organic compound. Alternative Names: Cholerythrin. CAS No. 635-65-4. Molecular formula: C33H36N4O6. Mole weight: 584.66. Appearance: Solid. Purity: 0.98. IUPACName: 3-[2-[[3-(2-Carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol- | |
| Biotin LC hydrazide | Biotin LC hydrazide is a long chain protein modification reagent. It is often used to target glycoproteins and glycans. It is carbohydrate reactive and is more sensitive than biotin hydrazide. Applications: Carbohydrate reactive with a spacer arm and is more sensitive than biotin hydrazide. Group: Coenzymes. Synonyms: Biotinamidocaproyl Hydrazide. CAS No. 109276-34-8. Mole weight: 371.5. Form: Solid. Biotinamidocaproyl Hydrazide; Biotin LC hydrazide; 109276-34-8. Cat No: COEC-017. | |
| Calcium D-(+)-pantothenate | Calcium D-(+)-pantothenate is a precursor for coenzyme A biosynthesis. Applications: A precursor for coenzyme a biosynthesis. Group: Coenzymes. Synonyms: D-Pantothenic acid calcium salt; Vitamin B5. CAS No. 137-08-6. Mole weight: 476.53. Appearance: Powder. Form: Solid. D-Pantothenic acid calcium salt; Vitamin B5; Calcium D-(+)-pantothenate; 137-08-6. Cat No: COEC-019. | |
| Calcium L-ascorbate dihydrate | Calcium L-ascorbate dihydrate, commonly called vitamin C calcium salt, is a biologically important antioxidant and a required coenzyme for various hydroxylation reactions and for collagen synthesis. Applications: A physiological antioxidant and coenzyme. Group: Coenzymes. Synonyms: L-Ascorbic acid calcium salt dihydrate; Vitamin C calcium salt. CAS No. 5743-28-2. Mole weight: 426.34. Appearance: Powder. Form: Solid. L-Ascorbic acid calcium salt dihydrate; Vitamin C calcium salt; Calcium L-ascorbate dihydrate; 5743-28-2. Cat No: COEC-049. | |
| Cardamonin | Cardamonin can be found from cardamom, and target various signaling molecules, transcriptional factors, cytokines and enzymes. Cardamonin can inhibit mTOR, NF-κB, Akt, STAT3, Wnt/β-catenin and COX-2. Cardamonin shows anticancer, anti-inflammatory, antimicrobial and antidiabetic activities. Group: Inhibitors. Alternative Names: cardamonin. CAS No. 18956-16-6. Molecular formula: C16H14O4. Mole weight: 270.28. Appearance: Solid. Purity: 0.96. IUPACName: (E)-1-(2,4-dihydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one. Canonical SMILES: COC1=CC (=CC (=C1C (=O)C=CC2=CC=CC=C2)O)O. Density: 1.282g/cm³. Catalog: ACM18956166. | |
| CDPI3 MGB CPG | CDPI3 MGB CPG is an exquisitely tailored and purposeful compound that garners marked proficiency within the realm of biomedicine, and has demonstrated efficacy in addressing diverse manifestations of cancer. Its unique mechanism of action bespeaks its ability to regulate crucial enzymes involved in tumor expansion, exclaiming its aptitude for both solid tumors and leukemia. Moreover, corresponding research has unveiled the possibility of applying this compound as an efficacious treatment modality for autoimmune disorders. Synonyms: 5-(6-(6-(6-(6-Dimethoxytrityloxyhexanoyl)-3,6,7,8-tetrahydropyrrolo[3,2-e]indole-2-carbonyl)-3,6,7,8-tetrahydropyrrolo[3,2-e]indole-2-carbonyl)-3,6,7,8-tetrahydropyrrolo[3,2-e]indole-2-carboxamido)pentyl-1-O-diglycoloyl long chain alkylamino CPG. Mole weight: 831.87. | |
| Cedrol | Cedrol is a bioactive sesquiterpene, a potent competitive inhibitor of cytochrome P-450 (CYP) enzymes. Cedrol inhibits CYP2B6-mediated bupropion hydroxylase and CYP3A4-mediated midazolam hydroxylation with Ki of 0.9 μM and 3.4 μM, respectively. Cedrol also has weak inhibitory effect on CYP2C8, CYP2C9, and CYP2C19 enzymes. Cedrol is found in cedar essential oil and poetesses anti-septic, anti-inflammatory, anti-spasmodic, tonic, astringent, diuretic, insecticidal, and anti-fungal activities. Group: Inhibitors. Alternative Names: Cypress camphor. CAS No. 77-53-2. Molecular formula: C15H26O. Mole weight: 222.37. Appearance: Pale yellow to yellow green solid. Purity: 0.99. IUPACName: (1S, 2R, 5S, 7R, 8R)-2, 6, 6, 8-Tetramethyltricyclo[5.3.1.01, 5]undecan-8-ol. Canonical SMILES: CC1CCC2C13CCC(C(C3)C2(C)C)(C)O. Density: 0.9479 g/cm³. Catalog: ACM77532. | |
| CGI1746 | CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation. Group: Inhibitors. Alternative Names: CGI1746; CGI-1746; CGI 1746. CAS No. 910232-84-7. Molecular formula: C34H37N5O4. Mole weight: 579.69. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: 4-(tert-butyl)-N-(2-methyl-3-(4-methyl-6-((4-(morpholine-4-carbonyl)phenyl)amino)-5-oxo-4,5-dihydropyrazin-2-yl)phenyl)benzamide. Canonical SMILES: O=C (NC1=CC=CC (C (N=C2NC3=CC=C (C (N4CCOCC4)=O)C=C3)=CN (C)C2=O)=C1C)C5=CC=C (C (C) (C)C)C=C5. Catalog: ACM910232847. | |
| Cheirolin | Cheirolin is a glucosinolate from plants of the Brassicaceae family which has shown to be a potent inducer of phase II detoxification enzymes. Applications: A phase ii detoxification enzyme activator. Group: Coenzymes. Synonyms: 1-Isothiocyanato-3-(methylsulfonyl)-propane. CAS No. 505-34-0. Mole weight: 179.26. Form: Solid. 1-Isothiocyanato-3-(methylsulfonyl)-propane; Cheirolin; 505-34-0. Cat No: COEC-110. | |
| Cholecalciferol | Cholecalciferol is a naturally occuring form of vitamin D. Reported that upon metabolic activation, Cholecalciferol induces cell differentiation and prevents proliferation of cancer cells. Cholecalciferol is an activator of VDR. Applications: An unhydroxylated form of vitamin d3. Group: Coenzymes. Synonyms: Vitamin D3; Activated 7-dehydrocholesterol; Calciol. CAS No. 67-97-0. Purity: ≥98%. Mole weight: 384.64. Appearance: Crystalline powder. Form: Solid. Vitamin D3; Activated 7-dehydrocholesterol; Calciol; Cholecalciferol; 67-97-0. Cat No: COEC-011. | |
| Cholesterol Oxidase, PEG Modified | PEG (Polyethylene glycol) modified cholesterol oxidase (Cholesterol oxidase PEG) is one of our premier cholesterol oxidase conjugates. Cholesterol oxidase is an enzyme that catalyzes the oxidation of cholesterol by oxygen into cholest-4-en-3-one and H2O2. This enzyme belongs to the family of oxidoreductases. Cholesterol oxidase has been used widely in the determination of serum cholesterol combined with other enzymes. PEG modified cholesterol oxidase provides better stability of this enzyme without major compromising its bioactivity. All our labeled cholesterol oxidase products were performed under mild reaction conditions to retain their maximum bioactivity. These conjugates were further purified by chromatography to ensure adequate applications both in-vitro and in-vivo. Conjugate ration: 20~50 peg5000r. solubility: soluble in aqueous buffer. Group: Enzymes. Synonyms: PEG Cholesterol Oxidase; Cholesterol Oxidase-polyethylene glycol; CHOD-polyethylene glycol; CHOD-PEG; PEG-CHOD; PEG-Cholesterol Oxidase. CHOD. Mole weight: ~61.8 kD. Activity: >10 units/mg solid. Storage: Store at -20°C. Form: Lyophilized powder. Source: Microorganism. PEG Cholesterol Oxidase; Cholesterol Oxidase-polyethylene glycol; CHOD-polyethylene glycol; CHOD-PEG; PEG-CHOD; PEG-Cholesterol Oxidase; Cholesterol Oxidase, PEG Modified. Cat No: NATE-1588. | |
| Coenzyme A sodium salt | This compound is an essential cofactor in enzymatic acetyl transfer reactions. Applications: An essential cofactor in enzymatic acetyl transfer reactions. Group: Coenzymes. Synonyms: CoA Na2. CAS No. 55672-92-9. Purity: ≥90%. Mole weight: 767.53. Appearance: Powder. Form: Solid. CoA Na2; Coenzyme A sodium salt; 55672-92-9. Cat No: COEC-003. | |
| Coenzyme Q10 | Coenzyme Q10 is an electron transport chain component of the mitochondria, which assists proton and electron transfer across the inner mitochondrial membrane. Studies indicate that Coenzyme Q10 can protect human endothelial cells from oxidative damage by modulating the nitric oxide pathway. In addition, Coenzyme Q10 inhibits LDL oxidation, a major process in the development of atherosclerosis. Coenzyme Q10 is known to suppress the down regulation of NOS3 (endothelial nitric oxide synthase, eNOS) and up-regulation of NOS2 (inducible nitric oxide synthase, iNOS). As a result of its ability to bind Ca2+, Coenzyme Q10 can transport this cation across artificial biomimetic membranes. Applications: A mitochondrial transporter chain component. Group: Coenzymes. Synonyms: CoQ10; Ubidecarenone; Ubiquinone-10; Q-10. CAS No. 303-98-0. Purity: ≥98%. Mole weight: 863.34. Appearance: Powder. Form: Solid. CoQ10; Ubidecarenone; Ubiquinone-10; Q-10; Coenzyme Q10; 303-98-0. Cat No: COEC-013. | |
| Coenzyme Q9 | Coenzyme Q9 is a co-enzyme that is lipid solumbe compononet of cell membranes. It is useful in electron and proton transport of liposome systems. It is also a useful tool in vitro to increase the life span of cells. Applications: A useful tool in vitro to increase the life span of cells. Group: Coenzymes. Synonyms: Ubiquinone-9. CAS No. 303-97-9. Purity: ≥98%. Mole weight: 795.23. Form: Solid. Ubiquinone-9; Coenzyme Q9; 303-97-9. Cat No: COEC-045. | |
| Creatine monohydrate | Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state. Applications: Involved with rapid atp production primarily in skeletal muscle tissue via the action of creatine kinase(s). Group: Coenzymes. Synonyms: N-Amidinosarcosine monohydrate. CAS No. 6020-87-7. Mole weight: 149.15. Form: Solid. N-Amidinosarcosine monohydrate; Creatine monohydrate; 6020-87-7. Cat No: COEC-096. | |
| Cyclodextrins | Cyclodextrins occur as white, practically odorless, fine crystalline powders, having a slightly sweet taste. Some cyclodextrin derivatives occur as amorphous powders. Synonyms: Cavitron; cyclic oligosaccharide; cycloamylose; cycloglucan; Encapsin; Schardinger dextrin. Product ID: PE-0591. Category: Solubilizing Agents; Stabilizing Agents. Product Keywords: Stabilizers; Solubilizer Excipients; PE-0591; Cyclodextrins; Solubilizing Agents; Stabilizing Agents;. UNII: Z1LH97KTRM. Grade: Pharmceutical Excipients. Administration route: α-cyclodextrin (injection); β-cyclodextrin (oral; topical); γ-cyclodextrin (IV injections). Dosage Form: α-cyclodextrin (injection preparations); β-cyclodextrin (oral tablets, topical gels); γ-cyclodextrin (IV injections). Stability and Storage Conditions: β-Cyclodextrin and other cyclodextrins are stable in the solid state if protected from high humidity. Cyclodextrins should be stored in a tightly sealed container, in a cool, dry place. Source and Preparation: Cyclodextrins are manufactured by the enzymatic degradation of starch using specialized bacteria. For example, b-cyclodextrin is produced by the action of the enzyme cyclodextrin glucosyltransferase upon starch or a starch hydrolysate. An organic solvent is used to direct the reaction that produces b-cyclodextrin, and to prevent the growth of microorganisms during the enzymatic reaction. The inso |  |
| D-(+)-Biotin | D-(+)-Biotin is a coenzyme that offers three possible binding sites. Applications: An important ubiquitous metabolism coenzyme. Group: Coenzymes. Synonyms: Vitamin H; 5-(2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid; Biotin. CAS No. 58-85-5. Purity: ≥99%. Mole weight: 244.3. Appearance: Powder. Form: Solid. Vitamin H; 5-(2-Oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid; Biotin; D-(+)-Biotin; 58-85-5. Cat No: COEC-007. | |
| D-Carnitine | D-Carnitine is used as a building block for antidiabetic, microbicidal compounds. Group: Coenzymes. CAS No. 541-14-0. Purity: >96%. Mole weight: 161.2. Form: Solid. D-Carnitine; 541-14-0. Cat No: COEC-102. | |
| DDD85646 | DDD85646 is a T. brucei N-myristoyltransferase (TbNMT) with an apparent Ki value of 1.44 nM. DDD85646 has potent activity against the enzyme (IC(50) = 2 nM) and T. brucei (EC(50) = 2 nM) in culture. DDD85646 has good oral pharmacokinetics and cures rodent models of peripheral HAT infection. DDD85646 provides an excellent tool for validation of T. brucei NMT as a drug target for HAT as well as a valuable lead for further optimization. Group: Others. Alternative Names: DDD85646; DDD-85646; DDD 85646. CAS No. 1215010-55-1. Molecular formula: C21H24Cl2N6O2S. Mole weight: 495.42. Appearance: Solid powder. Purity: >98%. IUPACName: 2,6-dichloro-4-[2-(1-piperazinyl)-4-pyridinyl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)-benzenesulfonamide. Canonical SMILES: O=S (C1=C (Cl)C=C (C2=CC (N3CCNCC3)=NC=C2)C=C1Cl) (NC4=C (C)N (C)N=C4C)=O. Catalog: ACM1215010551. | |
| Decanoyl coenzyme A monohydrate | Decanoyl coenzyme A is coupled with S-adenosylmethionine (SAM) by Vibrio cholera CqsA enzyme to produce a potent quorum-sensing molecule, 3-aminotridec-2-en-4-one (Ea-CAI-1). Applications: A fatty acyl coa. Group: Coenzymes. Synonyms: Decanoyl CoA Monohydrate. CAS No. 1264-57-9. Purity: ≥90%. Mole weight: 939.8. Appearance: Powder. Form: Solid. Decanoyl CoA Monohydrate; Decanoyl coenzyme A monohydrate; 1264-57-9. Cat No: COEC-051. | |
| D-Glucosamine 6-sulfate | D-Glucosamine 6-sulfate has been shown as an activator of ribozyme GlmS. Applications: A ribozyme glms activator. Group: Coenzymes. Synonyms: GlcN-6S; D-Glucosamine-6-O-sulphate. CAS No. 91674-26-9. Purity: ≥99%. Mole weight: 259.23. Appearance: Powder. Form: Solid. GlcN-6S; D-Glucosamine-6-O-sulphate; D-Glucosamine 6-sulfate; 91674-26-9. Cat No: COEC-112. | |
| Diaphorase-3, recombinant | Diaphorase-3, recombinant. Group: Enzymes. Synonyms: Diaphorase-3; Diaphorase 3; Diaphorase. Diaphorase. Activity: 1404 U/mg protein, 965 U/mg solid. Storage: At -20 to 5°C. Stable for one year after approval date. Form: Lyophilized (containing Potassium phosphate). Diaphorase-3; Diaphorase 3; Diaphorase. Cat No: NATE-1927. | |
| Diguanylate Cyclase from Agrobacterium vitis, recombinant | The diguanylate cyclase from Agrobacterium vitis has been engineered to remove phosphodiesterase activity, allowing for production of cyclic-diGMP from guanosine triphosphate (GTP) without the production of 5'-phosphoguanylyl-(3',5')-guanosine (pGpG). Applications: Useful for producing cyclic-digmp from gtp without production of pgpgcompletely lacks unwanted phosphodiesterase activityno product inhibition even at high concentrations of gtpremains active while immobilized to solid resin and retain enzymatic activity after several months of storagecan be used to synthesize radiolabeled cyclic digmp from radiolabeled gtp. Group: Enzymes. Synonyms: DGC; PleD; EC 2.7.7.65; 146316-82-7; Engineered Diguanylate Cyclase. Enzyme Commission Number: EC 2.7.7.65. CAS No. 146316-82-7. Purity: >99% based on SDS-PAGE analysis with coomassie blue. Mole weight: 56 kDa. Activity: 7.5 nmol min-1. Storage: at -80 °C; Multiple freeze/thaw cycles are not recommended. Form: Liquid. Source: E. coli. Species: Agrobacterium vitis. Diguanylate cyclase; DGC; PleD; EC 2.7.7.65; 146316-82-7; Engineered Diguanylate Cyclase. Cat No: NATE-1692. | |
| DL-3-Hydroxy-3-methylglutaryl coenzyme A trisodium salt | DL-3-Hydroxy-3-methylglutaryl coenzyme is a trisodium salt key intermediate in the biosynthesis of cholesterol, ketone bodies and terpenes. Applications: An intermediate in biosynthesis. Group: Coenzymes. Synonyms: DL-3-Hydroxy-3-methylglutaryl coenzyme A sodium salt. CAS No. 103476-21-7. Purity: ≥95%. Mole weight: 977.62. Appearance: Crystalline. Form: Solid. DL-3-Hydroxy-3-methylglutaryl coenzyme A sodium salt; DL-3-Hydroxy-3-methylglutaryl coenzyme A trisodium salt; 103476-21-7. Cat No: COEC-042. | |
| Emodin-d4 | Emodin-d4 is the deuterium labeled Emodin. Emodin (Frangula emodin), an anthraquinone derivative, is an anti-SARS-CoV compound. Emodin blocks the SARS coronavirus spike protein and angiotensin-converting enzyme 2 (ACE2) interaction. Emodin inhibits casein kinase-2 (CK2). Anti-inflammatory and anticancer effects. Emodin is a potent selective 11β-HSD1 inhibitor with the IC50 of 186 and 86 nM for human and mouse 11β-HSD1, respectively. Emodin ameliorates metabolic disorder in diet-induced obese mice. Group: Inhibitors. Alternative Names: Emodin-d4;1,3,8-Trihydroxy-6-Methyl-9,10-anthracenedione-d4;1,6,8-Trihydroxy-3-Methylanthraquinone-d4;4,5,7-Trihydroxy-2-Methyl- anthraquinone-d4;Archin-d4;EModol-d4;Frangula EModin-d4;Frangulic Acid-d4. CAS No. 132796-52-2. Molecular formula: C15H10O5. Mole weight: 270.2369. Appearance: Brownish Solid. Purity: 0.96. IUPACName: 1,3,6,8-tetradeuterio-2,4,5-trihydroxy-7-methylanthracene-9,10-dione. Canonical SMILES: O=C1C2=C (O)C ([2H])=C (C)C ([2H])=C2C (C3=C ([2H])C (O)=C ([2H])C (O)=C31)=O. Catalog: ACM132796522. | |
| Enasidenib | Enasidenib / AG-221 / CC-90007 is a potent and selective IDH2 inhibitor with potential anticancer activity (IDH2 = Isocitrate dehydrogenase 2). The mutations of IDH2 present in certain cancer cells result in a new ability of the enzyme to catalyze the NAPH-dependent reduction of α-ketoglutarate to R(-)-2-hydroxyglutarate (2HG). The production of 2HG is believed to contribute to the formation and progression of cancer. The inhibition of mutant IDH2 and its neoactivity is therefore a potential therapeutic treatment for cancer. Group: Fluorinated apis. Alternative Names: AG-221. CAS No. 1446502-11-9. Molecular formula: C19H17F6N7O. Mole weight: 473.38. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: 2-methyl-1-[[4-[6-(trifluoromethyl)pyridin-2-yl]-6-[[2-(trifluoromethyl)pyridin-4-yl]amino]-1,3,5-triazin-2-yl]amino]propan-2-ol. Catalog: OFC1446502119. | |
| Enzyme blend for treating organic waste | A proprietary enzyme blend that breaks down and solubilizes organic waste, including solids waste in manure pits and food processing plants. Applications: Food handling. Group: Enzymes. Synonyms: treating organic waste; Enzyme blend for treating organic waste; solubilizes organic waste; Waste Management Enzymes; solubilizes; organic waste; Waste Enzymes. Waste Management. Appearance: inquire. digesting waste oils; digest grease?fats and oils; Waste Management Enzymes; digesting; digesting waste oils; waste oils. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: WME-2712. | |
| Enzyme blend for treating septic tanks | A blend of naturally microbes, enzymes, plant extracts and buffers for the digestion of solid waste and elimination of odors in septic tanks and portable toilets. Applications: Organic waste. Group: Enzymes. Synonyms: treating septic tanks; enzyme for solid waste; odors in septic tanks and portable toilets; Waste Management Enzymes; solid; portable toiletswaste; tanks; odors in septic; odors; Enzyme blend for treating septic tanks. Waste Management. Appearance: inquire. digesting waste oils; digest grease?fats and oils; Waste Management Enzymes; digesting; digesting waste oils; waste oils. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form). Cat No: WME-2720. | |
| EPZ005687 | EPZ005687 is a selective EZH2 enzyme inhibitor with Ki of 24 nM. It is 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases. EPZ005687 can block trimethylation of the PRC2 target histone 3 lysine 27 with IC50 value of 80 nM, decreasing the proliferation of lymphoma cells carrying mutant, but not wild-type, EZH2. No development of preclinical research for the treatment of Cancer, Lymphoma and Solid tumours was reported. Uses: Cancer; lymphoma; solid tumours. Synonyms: EPZ005687; EPZ 005687; EPZ-005687; 1-Cyclopentyl-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-6-[4-(4-morpholinylmethyl)phenyl]-1H-indazole-4-carboxamide; 1-Cyclopentyl-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-6-(4-(morpholinomethyl)phenyl)-1H-indazole-4-carboxamide. Grades: 98%. CAS No. 1396772-26-1. Molecular formula: C32H37N5O3. Mole weight: 539.67. | |
| EPZ011989 | EPZ011989 is a potent, orally-available EZH2 inhibitor with robust in vivo activity. EPZ011989 demonstrates significant tumor growth inhibition in a mouse xenograft model of human B cell lymphoma. EPZ011989 represents a powerful tool for the expanded exploration of EZH2 activity in biology. Inhibitors of the protein methyltransferase Enhancer of Zeste Homolog 2 (EZH2) may have significant therapeutic potential for the treatment of B cell lymphomas and other cancer indications. The ability of the scientific community to explore fully the spectrum of EZH2-associated pathobiology has been hampered by the lack of in vivo-active tool compounds for this enzyme. Group: Inhibitors. Alternative Names: EPZ011989; EPZ-011989; EPZ 011989. CAS No. 1598383-40-4. Molecular formula: C35H51N5O4. Mole weight: 605.82. Appearance: Solid powder. Purity: >98%. IUPACName: N- ( (4, 6-dimethyl-2-oxo-1, 2-dihydropyridin-3-yl)methyl)-3- (ethyl ( (1r, 4r)-4- ( (2-methoxyethyl) (methyl)amino)cyclohexyl)amino)-2-methyl-5- (3-morpholinoprop-1-yn-1-yl)benzamide. Canonical SMILES: O=C (NCC1=C (C)C=C (C)NC1=O)C2=CC (C#CCN3CCOCC3)=CC (N (CC)[C@H]4CC[C@H] (N (CCOC)C)CC4)=C2C. Catalog: ACM1598383404. | |
| Feed enzyme complex for aquaculture | This complex is made in the way of Solid State Fermentation (SSF), not like pure enzymes which are made in the way of Liquid State Fermentation (LSF). Feed enzyme complex for livestock is designed according to fattening livestock's physiological characteristics and feed raw materials. Feed enzyme complex includes mainly the celluse (endocellulase, exocellulase, glucosidase), Xylanase (endoxylanase, exoxylanase,xylosidase),β-glucanase , mannose, acid protease, amylase, glucoamylase, pectinase with other endogenous enzymes which can well suit for character of the poultry digestive tract. The product through many optimization experiment, which can well digest non-starch polysaccharide, improve the use rate of feed. Applications: Feed enzyme complex for aquaculture. Group: Enzymes. Enzyme blend for aquaculture. Feed enzyme complex for aquaculture. Pack: 25 kgs/barrel or at customer's request. Cat No: Feed-2112. | |
| Feed enzyme complex for conventional diet | This complex is made in the way of Solid State Fermentation (SSF), not like pure enzymes which are made in the way of Liquid State Fermentation (LSF). Feed enzyme complex for livestock is designed according to fattening livestock's physiological characteristics and feed raw materials. Feed enzyme complex includes mainly the celluse (endocellulase, exocellulase, glucosidase), Xylanase (endoxylanase, exoxylanase,xylosidase),β-glucanase , mannose, acid protease, amylase, glucoamylase, pectinase with other endogenous enzymes which can well suit for character of the poultry digestive tract. The product through many optimization experiment, which can well digest non-starch polysaccharide, improve the use rate of feed. Applications: Feed enzyme complex for conventional diet. Group: Enzymes. Enzyme blend for conventional diet. Feed enzyme complex for conventional diet. Pack: 25 kgs/barrel or at customer's request. Cat No: Feed-2114. | |
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