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| Product | Description | |
|---|---|---|
| Statine | Statine is an unusual amino acid that occurs twice in the sequence of pepstatin, a protease inhibitor that is active against pepsin and other acid proteases. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (3S,4S)-Statine; (S,S)-Statine. CAS No. 49642-07-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-101877. |  |
| Statine Hydrochloride | Statine Hydrochloride. Synonyms: Sta(3S,4S)-OH HCl; (3S,4S)-4-Amino-3-hydroxy-6-methylheptanoic acid hydrochloride. Grade: ≥ 98% (Assay). Molecular formula: C8H17NO3·HCl. Mole weight: 211.69. |  |
| Statine Hydrochloride 98+% (TLC) | Statine Hydrochloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 50mg. US Biological Life Sciences. |  Worldwide |
| (3R,4S)-4-[(t-Butoxycarbonyl)amino]-3-hydroxy-6-methylheptanoic acid | (3R,4S)-4-[(t-Butoxycarbonyl)amino]-3-hydroxy-6-methylheptanoic acid. Synonyms: Boc-epi-Statine; Boc-(3R,4S)Sta-OH; (3R,4S)-3-hydroxy-6-methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]heptanoic acid; Boc-Sta(3R,4S)-OH; (3R,4S)-N-BOC-statine; (3R,4S)-4-tert-butoxycarbonylamino-3-hydroxy-6-methylheptanoic acid. Grade: 99%. CAS No. 66967-01-9. Molecular formula: C13H25NO5. Mole weight: 275.35. | |
| (3S,4S)-4-Amino-3-hydroxy-6-methylheptanoic acid | (3S,4S)-4-Amino-3-hydroxy-6-methylheptanoic acid. Synonyms: Statine; H-(3S,4S)Sta-OH. Grade: ≥ 98% (Assay). CAS No. 49642-07-1. Molecular formula: C8H17NO3. Mole weight: 175.23. | |
| Boc-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid | Boc-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid. Synonyms: Boc-Sta(3S,4S)-OH; (3S,4S)-4-(Boc-amino)-3-hydroxy-6-methylheptanoic acid; Boc-statine; BOC-STA-OH; (3S,4S)-4-((tert-Butoxycarbonyl)amino)-3-hydroxy-6-methylheptanoic acid; N-(t-butyloxycarbonyl)-statine; 4(S)-t-butoxycarbonylamino-3(S)-hydroxy-6-methylheptanoic acid; (3S,4S)-6-methyl-4-t-butoxycarbonylamino-3-hydroxyheptanoic acid; (3S,4S)-4-[(t-Butoxycarbonyl)amino]-3-hydroxy-6-methylheptanoic acid. Grade: ≥ 98% (HPLC). CAS No. 58521-49-6. Molecular formula: C13H25NO5. Mole weight: 275.34. | |
| Mevastatin | It is produced by the strain of Penicillum brevicompactum. It has weak anti-fungal activity and can inhibit the key enzyme (3-hydroxy-3-methyl glutaryl coenzyme A(HMGCoA) reductase) in the cholesterol biosynthesis pathway. It has been shown to lower cholesterol in animals and humans. It led the discovery of statins, lipid-lowering drugs. It is now used as a biochemical reagent. Uses: Hydroxymethylglutaryl-coa reductase inhibitors. Synonyms: Mevastatina; Mevastatine; Mevastatinum; ML-236B; Compactin; CS-500; CS 500; CS500; ML-236B; ML 236B; ML236B; Antibiotic ML 236B. Grade: >98%. CAS No. 73573-88-3. Molecular formula: C23H34O5. Mole weight: 390.51. | |
| Pepstatin A | Pepstatin A is a potent aspartic protease inhibitor, and also inhibits HIV replication.It is a hexa-peptide containing the unusual amino acid statine (Sta, (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid), having the sequence Isovaleryl-Val-Val-Sta-Ala-Sta (Iva-Val-Val-Sta-Ala-Sta). Uses: Protease inhibitors. Synonyms: Pepstatin; NSC 272671; NSC-272671; NSC272671; Pepstatin A; Pepstatina; Pepstatinum; Pepstatin A. Grade: >98%. CAS No. 26305-03-3. Molecular formula: C34H63N5O9. Mole weight: 685.89. | |
| 1,4-Anhydro-6-chloro-6-deoxy-D-glucitol | 1,4-Anhydro-6-chloro-6-deoxy-D-glucitol, an organic compound, holds significant importance as an intermediate in the synthesis of various drugs including renin inhibitors and statins. Despite its major industrial significance, 1,4-Anhydro-6-chloro-6-deoxy-D-glucitol has also caught the attention of research scientists due to its anti-diabetic potential via the inhibition of glucose uptake. Its versatile utility in the medicinal domain makes 1,4-Anhydro-6-chloro-6-deoxy-D-glucitol an intriguing and promising candidate for further exploration. Molecular formula: C6H11ClO4. Mole weight: 182.61. | |
| 3',5'-Dihydrodiol Simvastatin (Mixture of Diastereomers) | A metabolite of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: 3',5'-Dihydrodiol Simvastatin(Mixture of Diastereomers). CAS No. 198818-02-9. Molecular formula: C25H40O7. Mole weight: 452.58. | |
| 3α-Hydroxy pravastatin lactone | A metabolite of Pravastatin. Pravastatin is a member of the drug class of statins. It can be used for lowering cholesterol and preventing cardiovascular disease. Synonyms: 3α-iso-Pravastatin lactone; (2S)-2-Methylbutanoic acid (1S,6S,7R,8S,8aR)-1,2,6,7,8,8a-hexahydro-6-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester; SQ 31906 Lactone; Butanoic acid, 2-methyl-, (1S,6S,7R,8S,8aR)-1,2,6,7,8,8a-hexahydro-6-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, (2S)-; 6-Hydroxyisocompactin; 3-alpha-iso-Pravastatinp; Pravastatin 3-alpha-Hydroxy Lactone. Grade: ≥95%. CAS No. 85798-96-5. Molecular formula: C23H34O6. Mole weight: 406.51. | |
| 3''-Hydroxypravastatin | An impurity of Pravastatin. Pravastatin is a member of the drug class of statins. It can be used for lowering cholesterol and preventing cardiovascular disease. Synonyms: (βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-8-[(2S)-3-hydroxy-2-methyl-1-oxobutoxy]-2-methyl-1-naphthaleneheptanoic acid; (3R,5R)-3,5-Dihydroxy-7-((1S,2S,6S,8S,8aR)-6-hydroxy-8-(((2S)-3-hydroxy-2-methylbutanoyl)oxy)-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)heptanoic acid. Grade: >95%. CAS No. 250721-09-6. Molecular formula: C23H36O8. Mole weight: 440.53. | |
| 3-Hydroxy Simvastatin | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, 1,?2,?3,?7,?8,?8a-hexahydro-3-hydroxy-3,?7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)?ethyl]?-1-naphthalenyl ester. Grade: > 95%. CAS No. 134523-09-4. Molecular formula: C25H38O6. Mole weight: 434.57. | |
| 3-Hydroxy Simvastatin Acid, Sodium Salt | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: 3"-Hydroxy Simvastatin Acid Sodium Salt; 3-Hydroxy Simvastatin Acid, Sodium Salt. Grade: > 95%. Molecular formula: C25H39O7 Na. Mole weight: 451.59 22.99. | |
| 3-Methylene Simvastatin | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol in the liver. Synonyms: 3-Butenoic acid, 2,2,3-trimethyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester, [1S-[1α,3α,7β,8β(2S*,4S*),8aβ]]-; [1S-[1α,3α,7β,8β(2S*,4S*),8aβ]]-2,2,3-Trimethyl-3-butenoic Acid 1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl Ester; 3-Methylene Simvastatin Impurity; Simvastatin-3-en; (1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2,3-trimethylbut-3-enoate. Grade: ≥95%. CAS No. 79902-62-8. Molecular formula: C26H38O5. Mole weight: 430.58. | |
| 3-Oxo Atorvastatin Calcium | An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Synonyms: Calcium (R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-5-hydroxy-3-oxoheptanoate; (5R)-7-[2-(4-Fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(1-methylethyl)-1H-pyrrol-1-yl]-5-hydroxy-3-oxoheptanoic acid calcium salt; Calcium bis[(5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-(propan-2-yl)-1H-pyrrol-1-yl]-5-hydroxy-3-oxoheptanoate]; 3-Oxo Atorvastatin Calcium Salt. Grade: ≥95%. Molecular formula: C66H64CaF2N4O10. Mole weight: 1151.33. | |
| (3R,5R)-Fluvastatin Sodium Salt | 3R,5R)-Fluvastatin Sodium Salt is a prominent compound in the biomedical industry, aiding in the research of hypercholesterolemia. As a member of the esteemed statin class, it exerts its action by effectively inhibiting the pivotal enzyme HMG-CoA reductase. This paramount compound is frequently recommended to ameliorate LDL cholesterol levels. Grade: > 95%. Molecular formula: C24H25FNO4Na. Mole weight: 433.46. | |
| (3R,5R)-Rosuvastatin Calcium | (3R,5R)-Rosuvastatin Calcium is a derivative of Rosuvastatin, a statin medication used to treat cardiovascular disease. Synonyms: (3R,5R,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl (methyl sulfonyl) amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid calcium salt. CAS No. 1422515-55-6. Molecular formula: C44H54CaF2N6O12S2. Mole weight: 1001.14. | |
| (3R,5R)-Rosuvastatin Lactone | An impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Synonyms: Rosuvastatin (3R,5R)-Lactone; N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methyl-methanesulfonamide; Rosuvastatin-5R-lactone. CAS No. 1422954-11-7. Molecular formula: C22H26FN3O5S. Mole weight: 463.52. | |
| (3R)-Atorvastatin Cyclic Calcuim Salt (Isopropyl) Impurity | An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Synonyms: Atorvastatin Cyclic Calcium Salt (Isopropyl) Impurity; (3R)-4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H-pyrrolo[2,1-b][1,3]oxazin-2-yl}-3-hydroxybutanoic acid calcium salt; Atorvastatin Cyclic Isopropyl Impurity; Atorvastatin Cyclic 6-Hydroxy Impurity. Molecular formula: C66H68CaF2N4O14. Mole weight: 1219.36. | |
| (3R)-Atorvastatin Cyclic Sodium Salt (Isopropyl) Impurity | An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Synonyms: Atorvastatin Cyclic Sodium Salt (Isopropyl) Impurity; (3R)-4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H-pyrrolo[2,1-b][1,3]oxazin-2-yl}-3-hydroxybutanoic acid sodium salt; Atorvastatin Cyclic Isopropyl Impurity; Atorvastatin Cyclic 6-Hydroxy Impurity. Grade: 90%. Molecular formula: C33H34FN2NaO7. Mole weight: 612.62. | |
| (3R)-Hydroxperoxy Simvastatin | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, (1S,?3R,?7S,?8S,?8aR)?-1,?2,?3,?7,?8,?8a-hexahydro-3-hydroperoxy-3,?7-dimethyl-8-[2-[(2R,?4R)?-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]?ethyl]?-1-naphthalenyl ester. Grade: > 95%. CAS No. 1092716-42-1. Molecular formula: C25H38O7. Mole weight: 450.57. | |
| (3S,5R)-tert-Butyl Pitavastatin | A metabolite of Pitavastatin which is a chemically synthesized statin used for hypercholesterolaemia (elevated cholesterol) and for the prevention of cardiovascular disease. Grade: > 95%. Molecular formula: C29H32FNO4. Mole weight: 477.58. | |
| (3S, 5S)-Dihydroxy Simvastatin | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, 1,?2,?3,?4,?6,?7,?8,?8a-octahydro-4,?6-dihydroxy-3,?7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)?ethyl]?-1-naphthalenyl ester, [1S-[1α,?3α,?4β,?6α,?7β,?8β(2S*,?4S*)?,?8aβ]?]?- (9CI). Grade: > 95%. CAS No. 159143-77-8. Molecular formula: C25H40O7. Mole weight: 452.58. | |
| (3S)-Hydroxperoxy Simvastatin | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, (1S,?3S,?7S,?8S,?8aR)?-1,?2,?3,?7,?8,?8a-hexahydro-3-hydroperoxy-3,?7-dimethyl-8-[2-[(2R,?4R)?-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]?ethyl]?-1-naphthalenyl ester. Grade: > 95%. CAS No. 1092716-44-3. Molecular formula: C25H38O7. Mole weight: 450.57. | |
| (4S)-Hydroxy Simvastatin | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, 1,?2,?3,?4,?7,?8-hexahydro-4-hydroxy-3,?7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)?ethyl]?-1-naphthalenyl ester, [1S-[1α,?3α,?4β,?7β,?8β(2S*,?4S*)?]?]?- (9CI). Grade: > 95%. CAS No. 149949-05-3. Molecular formula: C25H38O6. Mole weight: 434.57. | |
| (5S)-Simvastatin EP Impurity N | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: (1S,3R,7S,8S,8aR)-8-(2-((2R,5R)-5-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate. CAS No. 477877-98-8. Molecular formula: C26H40O5. Mole weight: 432.60. | |
| 6S)-Hydroperoxy Simvastatin | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: Butanoic acid, 2,?2-dimethyl-, (1S,?6S,?7R,?8S,?8aR)?-1,?2,?6,?7,?8,?8a-hexahydro-6-hydroperoxy-3,?7-dimethyl-8-[2-[(2R,?4R)?-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]?ethyl]?-1-naphthalenyl ester; Butanoic acid, 2,2-dimethyl-, 1,2,6,7,8,8a-hexahydro-6-hydroperoxy-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester, [1S-[1α,6α,7β,8β(2S*,4S*),8aβ]]- (9CI). Grade: > 95%. CAS No. 149949-01-9. Molecular formula: C25H38O7. Mole weight: 450.57. | |
| (6S)-Hydroxy Simvastatin | A derivative of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: 2,2-Dimethylbutanoic Acid [1S-[1α,6α,7β,8β(2S*,4S*),8aβ]]-1,2,6,7,8,8a -Hexahydro-6-hydroxy-3,7-dimethyl)-8-[2-(tetrahydro -4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl Ester; 3'(S)-Hydroxy Simvastatin. Grade: > 95%. CAS No. 133645-46-2. Molecular formula: C25H38O6. Mole weight: 434.58. | |
| Actiketal | Actiketal is a glutarimide antibiotic isolated from Streptomyces pulveraceus subsp. epiderstagenes. Actiketal can inhibit the incorporation of [3H] thymidine into Balb/MB cells activated by epidermal growth factor, with IC50 of 14.5 μmol/L, which is stronger than its analog Actiphenol (109.6 μmol/L), but better than epidermal statin (Epiderstatin) 3000 times weaker. CAS No. 133658-47-6. Molecular formula: C15H15NO5. Mole weight: 289.28. | |
| Atorvastatin 3-Deoxyhept-2E-Enoic Acid (Calcium Salt) | An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Synonyms: (2E)-2,3-Dehydroxy Atorvastatin calcium; (2E,5S)-7-[2-(4-Fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-5-hydroxy-2-heptenoic Acid calcium salt. Grade: > 95%. Molecular formula: C66H64F2N4O8Ca. Mole weight: 1119.33. | |
| Atorvastatin calcium hydrate | Atorvastatin calcium salt trihydrate is a drug belonging to the statin class of drugs used to lower blood cholesterol levels. Atorvastatin calcium salt trihydrate has unique chemical properties that make it an effective tool in controlling high levels of low-density lipoprotein (LDL) cholesterol and triglycerides in the body, reducing the risk of heart attack and stroke. Atorvastatin calcium salt trihydrate works by inhibiting HMG-CoA reductase, the enzyme responsible for producing cholesterol in the liver. Uses: Scientific research. Group: Natural products. CAS No. 344423-98-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-112490. | |
| Atorvastatin Cyclic (Fluorophenyl) Sodium Salt Impurity | An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Synonyms: ATV-FX1 sodium salt. CAS No. 1315629-79-8. Molecular formula: C33H34FN2NaO7. Mole weight: 612.62. | |
| Atorvastatin Cyclic Sodium Salt (Isopropyl) Impurity | An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Synonyms: 4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H -pyrrolo[2,1-b][1,3]oxazin-2-yl}-3-hydroxybutanoic acid sodium salt; Atorvastatin Cyclic Isopropyl Impurity; Atorvastatin Epoxy Pyrrolooxazin 6-Hydroxy Analog (USP); Atorvastatin Cyclic 6-Hydroxy Impurity. Grade: 90%. CAS No. 1316291-19-6. Molecular formula: C33H34FN2NaO7. Mole weight: 612.62. | |
| Atorvastatin Diepoxide Calcium Salt | An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Synonyms: Atorvastatin diepoxide Calcium; 3,7-Dioxa-5-azatricyclo[4.1.0.02,4]heptane-5-heptanoic acid, 4-(4-fluorophenyl)-β,δ-dihydroxy-6-(1-methylethyl)-2-phenyl-1-[(phenylamino)carbonyl]-, calcium salt (2:1), (βR,δR)-; (βR,δR)-4-(4-Fluorophenyl)-β,δ-dihydroxy-6-(1-methylethyl)-2-phenyl-1-[(phenylamino)carbonyl]-3,7-dioxa-5-azatricyclo[4.1.0.02,4]heptane-5-heptanoic acid calcium salt. Grade: ≥95%. CAS No. 1807481-01-1. Molecular formula: C33H34FN2O7.1/2Ca. Mole weight: 1219.34. | |
| Atorvastatin EP Impurity A sodium salt | An impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Synonyms: Atorvastatin Impurity A sodium salt; 1H-Pyrrole-1-heptanoic acid, β,δ-dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-, sodium salt (1:1), (βR,δR)-; (3R,5R)-3,5-Dihydroxy-7-[5-(1-methylethyl)-2,3-diphenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]heptanoic acid sodium salt; Desfluoroatorvastatin sodium salt; Defluoro Atorvastatin sodium salt; (βR,δR)-β,δ-Dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic acid sodium salt; Atorvastatin calcium trihydrate impurity A [EP] sodium salt. Grade: ≥95%. CAS No. 1516864-05-3. Molecular formula: C33H35N2NaO5. Mole weight: 562.64. | |
| Atorvastatin lactone diepoxide | A derivative of Atorvastatin, a statin medication used to treat cardiovascular disease. Synonyms: Atorvastatin diepoxide (Lactone ring); 4-(4-Fluorophenyl)-6-(1-methylethyl)-N,2-diphenyl-5-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-3,7-dioxa-5-azatricyclo[4.1.0.02,4]heptane-1-carboxamide; 4-(4-Fluorophenyl)-5-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-6-isopropyl-N,2-diphenyl-3,7-dioxa-5-azatricyclo[4.1.0.02,4]heptane-1-carboxamide. Grade: ≥95%. CAS No. 2591410-14-7. Molecular formula: C33H33FN2O6. Mole weight: 572.62. | |
| Atorvastatin Lactone Diepoxide (Mixture of diastereomers) | A derivative of Atorvastatin, a statin medication used to treat cardiovascular disease. Synonyms: 4-(4-Fluorophenyl)-6-(1-methylethyl)-N,2-diphenyl-5-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-3,7-dioxa-5-azatricyclo[4.1.0.02,4]heptane-1-carboxamide; 4-(4-Fluorophenyl)-5-(2-(4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-6-isopropyl-N,2-diphenyl-3,7-dioxa-5-azatricyclo[4.1.0.02,4]heptane-1-carboxamide. Grade: ≥95%. CAS No. 1046118-40-4. Molecular formula: C33H33FN2O6. Mole weight: 572.64. | |
| Atorvastatin USP Related Compound A | Atorvastatin USP Related Compound A is an impurity in the synthesis of Atorvastatin, which is a competitive HMG-CoA reductase inhibitor. Atorvastatin is a lipid-lowering medication of the statin class. Atorvastatin suppresses the production of cholesterol and prevents some cardiovascular diseases. Synonyms: Calcium (3R,5R)-7-[2-isopropyl-4,5-diphenyl-3-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate (1:2); Atorvastatin Desfluoro impurity; (3R,5R)-7-[3-(phenylcarbamoyl)-2-isopropyl-4,5-diphenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoicacid, calcium salt; USP Atorvastatin Related Compound A; Defluoro Atorvastatin Calcium Salt; Atorvastatin Related Compound A; Calcium (3R,5R)-3,5-dihydroxy-7-(2-isopropyl-4,5-diphenyl-3-(phenylcarbamoyl)-1H-pyrrol-1-yl)heptanoate; 1H-Pyrrole-1-heptanoic acid, β,δ-dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-, calcium salt (2:1), (βR,δR)-; Calcium (βR,δR)-β,δ-dihydroxy-2-(1-methylethyl)-4,5-diphenyl-3-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoate (1:2). Grade: ≥95%. CAS No. 433289-83-9. Molecular formula: C66H70CaN4O10. Mole weight: 1119.38. | |
| Atorvastatin USP Related Compound B calcium salt | Atorvastatin USP Related Compound B is an impurity of Atorvastatin, a statin medication used to treat cardiovascular disease. Synonyms: USP Atorvastatin Related Compound B; Calcium (3S,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate (1:2); Atorvastatin 3S,5R Isomer; (3S,5R)-7-[3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid, calcium salt; (βS,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Calcium Salt; 1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, calcium salt (2:1), (βS,δR)-; Atorvastatin Related Compound B; (3S,5R)-Atorvastatin Calcium Salt. Grade: ≥95%. CAS No. 887196-25-0. Molecular formula: C66H68CaF2N4O10. Mole weight: 1155.34. | |
| Bemfivastatin hemicalcium | Bemfivastatin (PPD 10558) hemicalcium is an orally active lipid-lowering agent and HMG-CoA reductase inhibitor. Bemfivastatin hemicalcium enhances the activity of liver extracts. Bemfivastatin hemicalcium has no-observed adverse effect levels (NOAEL) with dosages of ≥320 mg/kg/d (rat developmental toxicity), ≥12.5 mg/kg/d (rabbit maternal toxicity), ≥25 mg/kg/d (rabbit developmental toxicity), respectively. Bemfivastatin hemicalcium can be used in the study of statin-related hypercholesterolemic myalgia in statin-intolerant patients. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PPD 10558 hemicalcium. CAS No. 805241-64-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106281A. | |
| Choline Fenofibrate | A new formulation of fenofibric acid, co-administered with statins. Group: Biochemicals. Alternative Names: 2-Hydroxy-N,N,N-trimethylethanaminium2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate; ABT 335; Trilipix. Grades: Highly Purified. CAS No. 856676-23-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Dalotuzumab | Dalotuzumab (MK-0646) is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R. Dalotuzumab acts by inhibiting IGF-1 - and IGF-2 -mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MK-0646; h7C10. CAS No. 1005389-60-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99284. | |
| Des(2-methylbutyryl) 6'-epipravastatin | An impurity of Pravastatin. Pravastatin is a member of the drug class of statins. It can be used for lowering cholesterol and preventing cardiovascular disease. Synonyms: (βR,δR,1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6,8-tetrahydroxy-2-methyl-1-naphthaleneheptanoic acid; (3R,5R)-7-((1S,2S,6R,8S,8aR)-6,8-Dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)-3,5-dihydroxyheptanoic acid; Pravastatin Impurity F (6'-epimer); Des(2-methylbutanoyl) 6'-epipravastatin. Grade: >95%. CAS No. 776294-80-5. Molecular formula: C18H28O6. Mole weight: 340.41. | |
| Dihydro-Simvastatin | An impurity of Simvastatin. Simvastatin is a lipid-lowering drug that inhibits HMG-CoA reductase. It is in the statin class of medications and works by decreasing the manufacture of cholesterol by the liver. Synonyms: (1S,3S,4aR,7S,8S,8aS)-8-(2-((2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl 2,2-dimethylbutanoate. CAS No. 92083-03-9. Molecular formula: C25H38O5. Mole weight: 418.6. | |
| DL-Mevalonolactone | DL-Mevalonolactone ((±)-Mevalonolactone;Mevalolactone) is the ?-lactone form of mevalonic acid, a precursor in the mevalonate pathway. DL-Mevalonolactone is orally active against HMGCR mutation and statin caused myopathy[3]. DL-Mevalonolactone induces inflammation and oxidative stress response with decreased mitochondrial membrane potential (MMP) and induces mitochondrial swelling[2][4]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Mevalonolactone; Mevalolactone. CAS No. 674-26-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg; 500 mg. Product ID: HY-107855. | |
| (E)-3-(1-Ethyl-3-(4-fluorophenyl)-1H-indol-2-yl)acrylaldehyde | An impurity of Fluvastatin. Fluvastatin is a statin medication primarily used to treat high cholesterol and reduce the risk of cardiovascular events. Synonyms: (E)-3-[1-Ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-2-propenal; 2-Propenal, 3-[1-ethyl-3-(4-fluorophenyl)-1H-indol-2-yl]-, (E)-; Fluvastatin Impurity 17. Grade: ≥95%. CAS No. 93937-37-2. Molecular formula: C19H16FNO. Mole weight: 293.33. | |
| Ezetimibe tetrahydropyran analog | An impurity of Ezetimibe. Ezetimibe is a cholesterol absorption inhibitor used to reduce low-density lipoprotein (LDL) cholesterol levels in the blood. It is commonly used alone or in combination with other cholesterol-lowering medications, such as statins, to manage hypercholesterolemia and related conditions. Synonyms: N,6-Bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide; Ezetimibe Tetrahydropyran Impurity; Ezetimibe THP analog; Ezetimibe Cyclized Impurity; Ezetimibe Cyclic ether; Ezetimibe Cyclic Ether Impurity; N,6-Bis(4-fluorophenyl)tetrahydro-2-(4-hydroxyphenyl)-2H-pyran-3-carboxamide. Grade: ≥95%. CAS No. 1050631-82-7. Molecular formula: C24H21F2NO3. Mole weight: 409.43. | |
| Fenofibrate | Fenofibrate (Tricor, Trilipix) is a compound of the fibrate class and fibric acid derivative.It is used alone or along with statins in the treatment of hypercholesterolemia and hypertriglyceridemia. Uses: Hypolipidemic agents. Synonyms: Propanoic acid, 2-[4-(4-chlorobenzoyl)phenoxy]-2-methyl-, 1-methylethyl ester; Ankebin; Antara; Clorofibrate; Elasterin; Fenobrat; Fenobrate; Fenogal; Fenoglide; Fenorate; Fenotard; Isopropyl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate; Isopropyl 2-[p-(p-chlorobenzoyl)phenoxy]-2-methylpropionate; LF 178; Lipanthyl; Lipanthyl supra; Lipanthylnano; Lipantil; Lipicard; Lipidil; Lipidil Supra; Lipirex; Lipivim; Lipoclar; Lipofen; Lipofene; Liposit; Lipsin; MeltDose; Nolipax; NSC 281319; Procetofen; Procetofene; Procetoken; Protolipan; Secalip; TriCor; Triglide. Grade: >98%. CAS No. 49562-28-9. Molecular formula: C20H21ClO4. Mole weight: 360.83. | |
| Fenofibrate-[d6] | Fenofibrate-[d6] is a labelled form of Fenofibrate. Fenofibrate (Tricor, Trilipix) is a compound of the fibrate class and fibric acid derivative. It is used alone or along with statins in the treatment of hypercholesterolemia and hypertriglyceridemia. Synonyms: Fenofibrate D6; 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methyl-propanoic Acid-d6 1-Methylethyl Ester; LF 178-d6; Lipanthyl-d6; Lipantil-d6; Lipidil Supra-d6; Lipirex-d6; Lipoclar-d6; Lipofene-d6; Liposit-d6; Lipsin-d6; MeltDose-d6; NSC 281319-d6; Nolipax-d6. Grade: 98% by HPLC; 99% atom D. CAS No. 1092484-56-4. Molecular formula: C20H15D6ClO4. Mole weight: 366.87. | |
| Fluvastatin | Fluvastatin is a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR) with IC50 of 8 nM. It belongs to a class of the statin drug and is structurally distinct from the fungal derivatives of this therapeutic class. It binds of the substrate HMG-CoA with Ki value of 0.3 nM but not with respect to binding of NADPH. It is marketed under the trade name Lescol® and is used to treat hypercholesterolemia and to prevent cardiovascular disease. It induces G2/M phase arrest and has antilipemic effect. Uses: Fluvastatin is used to treat hypercholesterolemia and to prevent cardiovascular disease. it has antilipemic effect. Synonyms: XU-62320; XU 62320; XU62320; Cranoc; Lescol; (+)-(3R,5S)-fluvastati; (E,3R,5S)-7-[3-(4-fluorophenyl)-1-propan-2-ylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid; 6-Heptenoic acid,7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-,[R*,S*-(E)]-. Grade: 99%. CAS No. 93957-54-1. Molecular formula: C24H26FNO4. Mole weight: 411.47. | |
| Fluvastatin Degradation Product (diastereomeric mixture) | Fluvastatin Degradation Product (diastereomeric mixture) is the various metabolites generated during the degradation process of Fluvastatin, which is a statin drug commonly prescribed for lowering cholesterol levels in patients with hyperlipidemia and cardiovascular diseases. Grade: > 95%. Molecular formula: C24H26FNO4. Mole weight: 411.48. | |
| Hexadecanedioic Acid | Hexadecanedioic Acid is a useful research intermediate for the studies of blood pressure regulations in humans. Hexadecandedioate works in collaboration with SLCO1B1 as a potential therapy for statin. Uses: This product is suitable for scientific research. Synonyms: Thapsic acid; 1,16-Hexadecanedioic acid; 1,14-Tetradecanedicarboxylic acid. Grade: 95%. CAS No. 505-54-4. Molecular formula: C16H30O4. Mole weight: 286.41. | |
| HMG499 | HMG499 is a potent and selective HMG-CoA reductase inhibitor. HMG499 can prevent statins-induced accumulation of HMGCR, reduce serum cholesterol levels and decrease atherosclerosis. CAS No. 2416941-68-7. Molecular formula: C33H54O3. Mole weight: 498.79. | |
| Homopravastatin sodium salt | An impurity of Pravastatin. Pravastatin is a member of the drug class of statins. It can be used for lowering cholesterol and preventing cardiovascular disease. Synonyms: Pravastatin EP Impurity C sodium salt; Pravastatin Impurity C sodium salt; (3R,5R)-3,5-Dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-[[(2S)-2-methylpentanoyl]oxy]-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid sodium salt; DES(2-methylbutanoyl)-2-methylpentanoyl pravastatin sodium salt; (βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[[(2S)-2-methyl-1-oxopentyl]oxy]-1-naphthaleneheptanoic acid sodium salt; 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8-[[(2S)-2-methyl-1-oxopentyl]oxy]-, sodium salt (1:1), (βR,δR,1S,2S,6S,8S,8aR)-; 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2-methyl-1-oxopentyl)oxy]-, monosodium salt, [1S-[1α(βS*,εS*),2α,6α,8β(R*)]]-; Pravastatin pentanoyl impurity sodium salt. Grade: >95%. CAS No. 159225-12-4. Molecular formula: C24H37NaO7. Mole weight: 460.55. | |
| Mevastatin | ?98% (HPLC), powder or crystals. Group: Fluorescence/luminescence spectroscopypharma & vet compounds & metabolitespharma & vet compounds & metabolitesapi standardsimpurity standardspharmaceutical toxicology. Alternative Names: Antibiotic ML 236B, L 637312, ML 236B lactone, Lovastatin Imp. A (EP), (2S)-2-Methylbutanoic acid (1S,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester, Compactin, Compactin (Penicillium), (1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-Methylbutanoate, (+)-Compactin, ML 236B, Statin I, 2-Methylbutanoic acid [1S-[1alpha(R*),7beta,8beta(2S*,4S*),8abeta]]-1,2,3,7,8,8a-hexahydro-7-methyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester,Mevastatin, CS 500 (antibiotic), NSC 281245, CS 500. |  |
| Mevastatin | Mevastatin (Compactin) is a first HMG-CoA reductase inhibitor that belongs to the statins class. Mevastatin is a lipid-lowering agent, and induces apoptosis , arrests cancer cells in G 0 /G 1 phase. Mevastatin also increases endothelial nitric oxide synthase (eNOS) mRNA and protein levels. Mevastatin has antitumor activity and has the potential for cardiovascular diseases treatment [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Compactin; ML236B. CAS No. 73573-88-3. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-17408. | |
| Mevastatin | Mevastatin (Compactin) is a first HMG-CoA reductase inhibitor that belongs to the statins class. Mevastatin is a lipid-lowering agent, and induces apoptosis, arrests cancer cells in G0/G1 phase. Mevastatin also increases endothelial nitric oxide synthase (eNOS) mRNA and protein levels. Mevastatin has antitumor activity and has the potential for cardiovascular diseases treatment. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Powder. CAS No. 73573-88-3. Molecular formula: C23H34O5. Mole weight: 390.51. Purity: 0.98. IUPACName: [(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate. Canonical SMILES: CCC(C)C(=O)OC1CCC=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O. Product ID: ACM73573883. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Nystatin | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspharma & vet compounds & metabolitespharma & vet compounds & metaboliteseuropean pharmacopoeia (ph. eur.)international reference standards for antibiotics (who)pharmacopoeial standards. Alternative Names: Mycostatin, Ceratocide, Stamycin, Biofanal, Fungicidin, Diastatin, Flagystatin, Mykostatyna, L-Nystatin, Nystex, Moronal (antibiotic), Nistatin, Nysfungin,Nystatin, Nystop, Candio-Hermal, Myconystatin, Nystavescent, Nyotran, Nystan, O-V Statin, Mycostatin Pastilles, Nystacid. | |
| Pepstatin | Pepstatin (Pepstatin A) is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin also inhibits HIV protease. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ahpatininc;pepsininhibitors735a;procidins735a;PEPSTATIN;PEPSTATIN A;X-VAL-VAL-STATYL-ALA-STATIN;(3S,4S)-4-AMINO-3-HYDROXY-6-METHYL-HEPTANOIC ACID;AHMHA ISOVALERYL-L-VAL-L-VAL-AHMHA-L-ALA-STA. Product Category: Inhibitors. Appearance: Solid. CAS No. 26305-03-3. Molecular formula: C34H63N5O9. Mole weight: 685.892. Purity: 0.984. Density: 1.1±0.1 g/cm3. Product ID: ACM26305033. Alfa Chemistry ISO 9001:2015 Certified. | |
| Piroxicam | Non-steroidal anti-inflammatory with long half-life. Cyclooxygenase inhibitor. Clinically useful NSAID. Piroxicam may be useful for chemoprevention of solid cancers via inhibition of cyclooxygenase. Statins, which are used clinically for anti-inflammation, immunomodulation, neuroprotection, and im-provement of bone metabolism, have remarkable efficiency as individual drugs or assistant medicines that affect cell viability by inducing apoptosis.. Group: Biochemicals. Alternative Names: 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide;Artroxicam; Baxo; Bruxicam; CHF 1251; CP 16171; Caliment; Roxicam; Roxiden; Sasulen; Solocalm. Grades: Highly Purified. CAS No. 36322-90-4. Pack Sizes: 5g, 10g. Molecular Formula: C??H??N?O?S, Molecular Weight: 331.35. US Biological Life Sciences. | Worldwide |
| Pitavastatin calcium | Pitavastatin calcium is a novel member of the medication class of statins. Synonyms: (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt; Flovas; Livalo; NK 104; NK 104 (acid); Pitava 1; Pitavastatin Hemicalcium; Pitavastatin Calcium Salt; calcium (E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate; Nisvastatin; NK-104; P 872441; P-872441; P872441. Grade: 96%. CAS No. 147526-32-7. Molecular formula: C50H46CaF2N2O8. Mole weight: 880.98. | |
| Pitavastatin-[d4] Calcium Salt | Pitavastatin-[d4] Calcium Salt, is the labelled analogue of Pitavastatin. Pitavastatin is a member of the blood cholesterol lowering medication class of statins. It is an inhibitor of HMG-CoA reductase. Synonyms: Pitavastatin D4 Calcium Salt. Grade: > 95%. Molecular formula: C50H38D8F2N2O8Ca. Mole weight: 889.03. | |
| Pitavastatin-d5 Lactone | A labeled metabolite of Pitavastatin. Recent studies have shown that conversion between acid and lactone forms occurs in the body, drug-drug interaction should be considered on both acid and lactone forms. The inhibitory effects of statins on CYP metabolic activities and MDR1 transporting activity were investigated using human liver microsomes and MDR1-overexpressing LLC-GA5-COL150 cells. Group: Biochemicals. Alternative Names: (4R, 6S) -6- [ (1E) -2- [2- (Cyclopropyl-d5) -4- (4-fluorophenyl) -3-quinolinyl] ethenyl] tetrahydro-4-hydroxy-2H-pyran-2-one; [4R-[4α,6 β (E) ] ] -6- [2- [2- (Cyclopropyl-d5) -4- (4-fluorophenyl) -3-quinolinyl] ethenyl] tetrahydro-4-hydroxy-2H-pyran-2-one; NK 104-d5; NK 104-d5 (lactone); Nisvastatin-d5; P 872441-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| PNGase F from Elizabethkingia meningoseptica, Recombinant | In enzymology, a peptide-N4-(N-acetyl-beta-glucosaminyl) asparagine amidase (EC 3.5.1.52) is an enzyme that catalyzes a chemical reaction that cleaves a N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and a peptide containing an aspartate residue. This enzyme belongs to the family of hydrolases, specifically those acting on carbon-nitrogen bonds other than peptide bonds in linear amides. Applications: Highly purified material can be used for preparative deglycosylation or for analytical applications in gel, in solution, or on blot membranes. ...n 50% (v/v) glycerol and 50% (v/v) 20 mM Potassium Phosphate, pH 7.5. Type III, buffered aqueous solution, Supplied as a solution in 20 mM Tris HCl, pH 7.5, 50 mM NaCl and 1 mM EDTA. Source: E. coli. Species: Elizabethkingia meningoseptica. glycopeptide N-glycosidase; glycopeptidase; N-oligosaccharide glycopeptidase; N-glycanase; glycopeptidase; Jack-bean glycopeptidase; PNGase A; PNGase F; glycopeptide N-glycosidase; peptide-N4-(N-acetyl-β-glucosaminyl)asparagine amidase; EC 3.5.1.52; PNGase F; 83534-39-8. Pack: PNGase F was used for deglycosylation of P-glycoprotein in a study to investigate the dual impact of statins on p-glycoprotein and its effect on dox |  |
| Pravastatin-[d3] Sodium Salt | Pravastatin-[d3] Sodium Salt is the labelled analogue of Pravastatin. Pravastatin is a member of the drug class of statins. It can be used for lowering cholesterol and preventing cardiovascular disease. Synonyms: Pravastatin-d3 Sodium Salt. Grade: 95% by HPLC; 95% atom D. CAS No. 1329836-90-9. Molecular formula: C23H32D3NaO7. Mole weight: 449.53. | |
| Pravastatin Lactone-[d3] | Pravastatin Lactone-[d3] is the labelled analogue of Pravastatin Lactone, which is a metabolite of Pravastatin. Pravastatin is a member of the drug class of statins. It can be used for lowering cholesterol and preventing cardiovascular disease. Synonyms: Pravastatin Lactone D3; (2S)-2-(Methyl-d3)butanoic Acid (1S,3S,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3-hydroxy-7-methyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl Ester. Grade: 97%; ≥99% atom D. CAS No. 1217769-04-4. Molecular formula: C23H31D3O6. Mole weight: 409.54. | |
| Pravastatin Sodium Salt | Pravastatin sodium is the sodium salt of pravastatin, a ring- opened member of the statin family. Pravastatin is produced biosynthetically from compactin (mevastatin) by a number of micro-organisms, notablyAbsidia, Cunninghamella, Syncephalastrum, Nocardia or Streptomyces. Typically, statins like compactin, lovastatin and simvastatin possess a b-hydroxy lactone ring which is a pro-drug for the readily ring-opened dihydroxyacid generally regarded as the active HMG-CoA inhibitor. Importantly, the free carboxylic acid enables pravastatin to be freely water soluble within biological pH ranges. Pravastatin is used therapeutically to reduce LDL cholesterol. Group: Biochemicals. Grades: Highly Purified. CAS No. 81131-70-6. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Rosuvastatin EP Impurity F | Rosuvastatin EP Impurity F is an impurity of Rosuvastatin, which is a statin medication used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. Synonyms: Rosuvastatin Calcium EP Impurity F; tert-Butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate; tert-Butyl [(4R,6S)-6-[(1E)-2-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]ethen-1-yl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate; 1,1-Dimethylethyl [(4R,6S)-6-[(E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-pyrimidin-5-yl]ethenyl]-2,2-dimethyl-1,3-dioxan-4-yl]acetate; 1,3-Dioxane-4-acetic acid, 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6S)-; (4R,6S)-6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl (4R,6S)-6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate; USP Rosuvastatin Related Compound C; Rosuvastatin Related Compound C; Rosuvastatin USP Related Compound C. Grade: ≥95%. CAS No. 289042-12-2. Molecular formula: C29H40FN3O6S. Mole weight: 577.72. | |
| (S)-3''-Hydroxypravastatin sodium salt | An impurity of Pravastatin. Pravastatin is a member of the drug class of statins. It can be used for lowering cholesterol and preventing cardiovascular disease. Synonyms: (S)-3''-Hydroxy Pravastatin Sodium Salt; 1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-8-[(2S,3S)-3-hydroxy-2-methyl-1-oxobutoxy]-2-methyl-, sodium salt (1:1), (βR,δR,1S,2S,6S,8S,8aR)-; Pravastatin Sodium EP Impurity E sodium salt; Pravastatin EP Impurity E sodium salt; Pravastatin Impurity E sodium salt; 3''-(S)-Hydroxypravastatin sodium salt; (βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-8-[(2S,3S)-3-hydroxy-2-methyl-1-oxobutoxy]-2-methyl-1-naphthaleneheptanoic acid sodium salt. Grade: >95%. CAS No. 722504-45-2. Molecular formula: C23H35NaO8. Mole weight: 462.52. | |
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