Thymidylic Suppliers USA
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Product | Description | |
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3`-Deoxy-5`-thymidylic Acid Quick inquiry Where to buy Suppliers range | 3`-Deoxy-5`-thymidylic Acid has been shown to complex with human thymidylate kinase via hydrogen bonding between Arg97 residues and phosphate groups. This interaction leads to the closed P-loop conformation in human thymidylate kinase, which promotes phosphorylation of nucleotides and has the potential as a model for novel compounds as a result of structure-based design studies. Group: Biochemicals. Grades: Highly Purified. CAS No. 3715-64-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C10H15N2O7P, Molecular Weight: 306.211. US Biological Life Sciences. | Worldwide |
5'-?O-?[Bis(4-?methoxyphenyl)?phenylmethyl]?-?3'-?Thymidylic Acid Bis(2-?cyanoethyl) Ester Quick inquiry Where to buy Suppliers range | 5'-O-[Bis(4-methoxyphenyl)?phenylmethyl]?-3'-Thymidylic Acid Bis(2-cyanoethyl) Ester is an intermediate in synthesizing Thymidine 5'-Triphosphate, 3'-Phosphate Triethylamine Salt, a derivative of Thymidine 5'-Triphosphate which is used for the biosynthesis of deoxyribonucleic acids by DNA polymerases and reverse transcriptases. Synonyms: Bis(2-cyanoethyl) ((2R,3S,5R)-2-(Hydroxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl) Phosphate. CAS No. 76759-76-7. Molecular formula: C16H21N4O8P. Mole weight: 428.33. | |
5'-Thymidylic acid, disodium salt Quick inquiry Where to buy Suppliers range | 5'-Thymidylic acid, disodium salt is a paramount biomedical compound, playing the role of a nucleotide analog. It exerts its inhibitory prowess on viral DNA replication, thereby impeding the rampant multiplication of the virus. Synonyms: Thymidine-5'-monophosphate disodium salt; sodium ((2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl phosphate. Grades: ≥97% by HPLC. CAS No. 33430-62-5. Molecular formula: C10H13N2Na2O8P. Mole weight: 366.17. | |
POLYDEOXYADENYLIC-THYMIDYLIC ACID SODIUM SALT Quick inquiry Where to buy Suppliers range | POLYDEOXYADENYLIC-THYMIDYLIC ACID SODIUM SALT. Group: Oligonucleotide Polymers and Copolymers. CAS No. 86828-69-5. | |
1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-b-L-arabinofuranosyl)-uracil Quick inquiry Where to buy Suppliers range | 1-(2'-deoxy-2'-fluoro-3',5'-di-O-benzoyl-b-L-arabinofuranosyl)-uracil is a nucleoside analogue useful in cancer treatment research. This nucleoside analogue selectively interacts with a thymidylate synthase, inhibiting DNA synthesis thereby disrupting tumor cell growth. Synonyms: 1-(3,5-Di-O-benzoyl-2-deoxy-2-fluoro-beta-L-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione; 2,4(1H,3H)-Pyrimidinedione, 1-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-L-arabinofuranosyl)-; 3,5-di-O-benzoyl-1,2-dideoxy-2-fluoro-1-uracil-1-yl-beta-L-arabino-pentofuranose. CAS No. 1312300-53-0. Molecular formula: C23H19FN2O7. Mole weight: 454.40. | |
1-(2-Deoxy-b-D-threo-pentofuranosyl)-5-fluorouracil Quick inquiry Where to buy Suppliers range | 1-(2-Deoxy-b-D-threo-pentofuranosyl)-5-fluorouracil, an effective antineoplastic agent employed in the management of diverse malignancies such as colorectal, breast, and pancreatic cancer, showcases its mechanistic action by suppressing the vital enzyme, thymidylate synthase, thereby impeding DNA synthesis. Undoubtedly, this compound's profound pharmacological features render it an indispensable asset within the biomedicine realm, proficiently combating a myriad of malignant conditions. Synonyms: 5-Fluoro-1-[(2R,4R,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione. CAS No. 955-24-8. Molecular formula: C9H11FN2O5. Mole weight: 246.19. | |
2'-Deoxy-5-trifluoromethyluridine-5'-monophosphate Quick inquiry Where to buy Suppliers range | 2'-Deoxy-5-trifluoromethyluridine-5'-monophosphate is a vital compound in the biomedical industry. It is used in the development of antiviral drugs, particularly those aimed at treating RNA-based viruses such as HIV and hepatitis C. Synonyms: α,?α,?α-Trifluoro-5'-thymidylic acid; Trifluridine-5-phosphate; 5-Trifluoromethyl-2'-deoxyuridylic acid. CAS No. 345-02-8. Molecular formula: C10H12F3N2O8P. Mole weight: 376.18. | |
3-Deoxy-3-fluorothymidine-5-monophosphate-d3 Disodium Salt Quick inquiry Where to buy Suppliers range | A thymidine-5'-O-monophosphate analogue as inhibitors of Mycobacterium tuberculosis thymidylate kinase. Group: Biochemicals. Alternative Names: 3'-Deoxy-3'-fluoro-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
3'-Deoxy-3'-fluorothymidine-5'-monophosphate-d3 Disodium Salt Quick inquiry Where to buy Suppliers range | A thymidine-5'-O-monophosphate analogue, for Mycobacterium tuberculosis thymidylate kinase inhibition. Synonyms: 3'-Deoxy-3'-fluoro-5'-thymidylic Acid-d3 Disodium; 2',3'-Dideoxy-3'-fluoro-5-methyluridine-d3 5'-(Dihydrogen Phosphate) Disodium; 3'-Deoxy-3'-fluoro-thymidine-d3 Monophosphate Disodium; 3'-Fluoro-3'-deoxythymidine-d3 Monophosphate Disodium. Molecular formula: C10H9D33FN2Na2O7P. Mole weight: 371.18. | |
3-Deoxy-3-fluorothymidine-5-monophosphate Disodium Salt Quick inquiry Where to buy Suppliers range | A thymidine-5'-O-monophosphate analogue as inhibitors of Mycobacterium tuberculosis thymidylate kinase. Group: Biochemicals. Alternative Names: 3'-Deoxy-3'-fluoro-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
3'-Deoxy-3'-fluorothymidine-5'-monophosphate Disodium Salt Quick inquiry Where to buy Suppliers range | A thymidine-5'-O-monophosphate analogue as inhibitors of Mycobacterium tuberculosis thymidylate kinase. Synonyms: 3'-Deoxy-3'-fluoro-5'-thymidylic Acid Disodium; 2',3'-Dideoxy-3'-fluoro-5-methyluridine 5'-(Dihydrogen Phosphate) Disodium; 3'-Deoxy-3'-fluorothymidine Monophosphate Disodium; 3'-Fluoro-3'-deoxythymidine Monophosphate Disodium. Grades: 95%. CAS No. 1316845-74-5. Molecular formula: C10H12FN2Na2O7P. Mole weight: 368.16. | |
3-Fluoro-3-deoxythymidine monophosphate Quick inquiry Where to buy Suppliers range | 3-Fluoro-3-deoxythymidine monophosphate. Group: Heterocyclic Organic Compound. Alternative Names: 2,3-dideoxy-3-fluoro-5-methyluridine 5-(Dihydrogen Phosphate);3'-Deoxy-3'-fluorothymidine-5'-monophosphate;3-Deoxy-3-fluoro-5-thymidylic Acid;3-Deoxy-3-fluorothymidine Monophosphate;3-Fluoro-3-deoxythymidine Monophosphate. CAS No. 25520-83-6. Molecular formula: C10H14FN2O7P. Mole weight: 0. | |
4-[2-(2-Amino-4,5,6,7-tetrahydro-4,6-dioxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 4-[2-(2-Amino-4,5,6,7-tetrahydro-4,6-dioxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid methyl ester is one of pemetrexed metabolites. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Benzoic acid, 4-[2-(2-amino-4,5,6,7-tetrahydro-4,6-dioxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]-, methyl ester; Pemetrexed Impurity 63; Methyl 4-[2-(2-amino-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate; Methyl 4-(2-(2-imino-4,6-dioxo-2,3,4,5,6,7-hexahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoate. Grades: ≥95%. CAS No. 1320346-43-7. Molecular formula: C16H16N4O4. Mole weight: 328.32. | |
5-(3-Amino-1-propen-1-yl)-2'-deoxyuridine Quick inquiry Where to buy Suppliers range | 5-(3-Amino-1-propen-1-yl)-2'-deoxyuridine, a potent chemotherapeutic agent against multiple types of cancer, works by inducing apoptosis and inhibiting DNA synthesis in malignant cells. Its active ingredient thwarts thymidylate synthase, blocking thymidine production and ultimately halting replication, stopping cancer in its tracks. This widely-used nucleoside treatment targets advanced cases of colon, ovarian, and breast cancer with remarkable success. Synonyms: 5-(3-Amino-1-propenyl)-2'-deoxyuridine; 5-[(E)-3-Amino-1-propenyl]-2'-deoxyuridine; Uridine, 5-(3-amino-1-propenyl)-2'-deoxy-; 5-[(1E)-3-Amino-1-propen-1-yl]-2'-deoxyuridine. Grades: ≥97% by HPLC. CAS No. 143908-73-0. Molecular formula: C12H17N3O5. Mole weight: 283.28. | |
5-Bromo-dUMP Quick inquiry Where to buy Suppliers range | 5-Bromo-dUMP is a highly active inhibitor of thymidylate synthase, serving as a pivotal component in hindering the catalytic ability of this vital enzyme involved in the research and development of DNA. Its efficacious employment as an antitumor compound against diverse malignancies proficiently impedes the generation of DNA, thus efficaciously curbing the proliferation of malignant cells inherent to cancerous growths. Synonyms: (5Br-dUMP); 5-Bromo-2'-deoxyuridine-5'-monophosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 6666-38-2. Molecular formula: C9H12N2O8PBr (free acid). Mole weight: 387.08 (free acid). | |
5'-Deoxy-5'-fluorothymidine Quick inquiry Where to buy Suppliers range | 5'-Deoxy-5'-fluorothymidine, a compound of utmost significance in the biomedical field, manifests its indispensability in countering a diverse range of malignant neoplasms. Its profound therapeutic efficacy arises from its ability to impede the crucial enzymatic function of thymidylate synthase, pivotal for the replication and mending of DNA. Commencing with colorectal malignancies, this extraordinary product finds extensive utilization in chemotherapy protocols tailored for breast and pancreatic cancers as well. Synonyms: 2',5'-Dideoxy-5'-fluorothymidine. CAS No. 17199-43-8. Molecular formula: C10H13FN2O4. Mole weight: 244.22. | |
5-Fluorouracil Quick inquiry Where to buy Suppliers range | Fluorouracil (5-Fluoracil, 5-FU) is a DNA/RNA synthesis inhibitor, which interrupts nucleotide synthetic by inhibiting thymidylate synthase (TS). Synonyms: 5-FU; Fluorouracil; Adrucil. Grades: >98%. CAS No. 51-21-8. Molecular formula: C4H3FN2O2. Mole weight: 130.08. | |
5-Fluoro-UTP Quick inquiry Where to buy Suppliers range | 5-Fluoro-UTP is an DNA/RNA synthesis inhibitor that terminate synthesis of nucleotide through inhibiting thymidylate synthase. It is used as an anticancer drug. Uses: 5-fluoro-utp is an dna/rna synthesis inhibitor. Synonyms: (5F-UTP); 5-Fluoro-uridine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. CAS No. 3828-96-4. Molecular formula: C9H14N2O15P3F (free acid). Mole weight: 502.13 (free acid). | |
5'-Tosyl Thymidine Quick inquiry Where to buy Suppliers range | A nucleoside analogue as inhibitors of thymidylate kinases. Synonyms: 5'-(4-Methylbenzenesulfonate)thymidine; 5'-O-(p-Toluenesulfonyl)thymidine; 5'-O-Tosylthymidine; NSC 69443. Grades: 98%. CAS No. 7253-19-2. Molecular formula: C17H20N2O7S. Mole weight: 396.41. | |
5-Trifluorothymidine Quick inquiry Where to buy Suppliers range | Trifluorothymidine is an inhibitor of TS (thymidylate synthase). It is also a substrate used to study the specificity and kinetics of thymidine kinases. Acts as an anti-herpesvirus drug by blocking viral DNA replication. Decreases CRISPR-mediated HDR (homology-directed repair) efficiency. Group: Biochemicals. Alternative Names: Trifluridine; Trifluorothymine Deoxyriboside; α, α, α-Trifluorothymidine; 2-Deoxy-5- (trifluoromethyl) uridine; 5-(Trifluoromethyl)-2-deoxyuridine; Viroptic. Grades: Highly Purified. CAS No. 70-00-8. Pack Sizes: 100mg, 250mg, 1g. Molecular Formula: C??H??F?N?O?, Molecular Weight: 296.2. US Biological Life Sciences. | Worldwide |
6-Aza-2-thiothymine Quick inquiry Where to buy Suppliers range | 6-Aza-2-thiothymine, a nucleoside analog widely utilized in cancer research, is profoundly effective in inhibiting thymidylate synthase; hence, it's active against several cancer cell lines. Furthermore, the compound's promising potential as a radiosensitizer renders it an excellent option for the management of solid tumors. This ground-breaking analog with unparalleled efficacy and versatility is a definitive focal point of modern-day cancer research. Synonyms: 2-Thio-6-azathymine; 6-Azathiothymine; 6-Methyl-3-thioxo-3,4-dihydro-1,2,4-triazin-5(2H)-one; 3-mercapto-6-methyl-1,2,4-triazin-5(4H)-one; 6-Methyl-3-thioxo-3,4-dihydro-2H-[1,2,4]triazin-5-one; 1,2,4-Triazin-5(2H)-one, 3,4-dihydro-6-methyl-3-thioxo-; NSC 1609; NSC 38618; 3-Mercapto-6-methyl-as-triazin-5-ol; NSC 102906; 3,4-Dihydro-6-methyl-3-thioxo-1,2,4-triazin-5(2H)-one; 6-Methyl-3-thio-as-triazine-3,5(2H,4H)-dione. CAS No. 615-76-9. Molecular formula: C4H5N3OS. Mole weight: 143.17. | |
ANX-510 Quick inquiry Where to buy Suppliers range | ANX-510 is a folate-based biomodulator with potential antineoplastic activity. 5,10-methylenetetrahydrofolate (MTHF) stabilizes the covalent binding of the fluorouracil metabolite 5-5-fluoro-2'-deoxyuridine-5'-O-monophosphate (FdUMP) to its target enzyme, thymidylate synthase, which results in inhibition of thymidylate synthase, depletion of thymidine triphosphate (TTP), a necessary constituent of DNA, and tumor cell death. Synonyms: 5,10-Methylenetetrahydrofolic acid; 5,10-Methylene-tetrahydrofolate; Tetrahydromethylenefolate; N-{4-[3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl}-L-glutamic acid. CAS No. 3432-99-3. Molecular formula: C20H23N7O6. Mole weight: 457.44. | |
AP4dT Quick inquiry Where to buy Suppliers range | AP4dT is a novel and auspicious antiviral drug exhibiting compelling efficacy against HCV by suppressing viral RNA polymerase enzyme, thereby restraining viral genome replication. Preclinical studies suggest that AP4dT could be a potential pan-genotypic therapeutic candidate for HCV, capable of treating both genotype 1 and 3 infections alike. Synonyms: P1-(5'-Adenosyl) P4-[5'-(2'-deoxy-thymidyl)] tetraphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 13457-68-6. Molecular formula: C20H29N7O20P4 (free acid). Mole weight: 811.38 (free acid). | |
AP5dT Quick inquiry Where to buy Suppliers range | AP5dT is an exceptional synthetic nucleoside analog, facilitating the exploration of intricate DNA replication and repair mechanisms. aP5dT can amplify the comprehension of virally-inflicted ailments (e.g., HIV, herpes) as well as diverse DNA-centric maladies. Synonyms: P1-(5'-Adenosyl) P5-[5'-(2'-deoxy-thymidyl)] pentaphosphate, Triethylammonium salt. Grades: ≥ 95% by HPLC. CAS No. 103137-88-8. Molecular formula: C20H30N7O23P5 (free acid). Mole weight: 891.36 (free acid). | |
BGC-638 Quick inquiry Where to buy Suppliers range | BGC-638, an analogue of BGC-945, is a thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)-overexpressing tumors. Synonyms: BGC 638; BGC638; CB300638; CB-300638; D-Glutamic acid, N-(4-(2-propyn-1-yl((6S)-4,6,7,8-tetrahydro-2-methyl-4-oxo-3H-cyclopenta(g)quinazolin-6-yl)amino)benzoyl)-L-gamma-glutamyl-. CAS No. 416852-27-2. Molecular formula: C32H33N5O9. Mole weight: 631.64. | |
BGC-945 Quick inquiry Where to buy Suppliers range | BGC 945 is a cyclopenta[g]quinazoline-based, thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)-overexpressing tumors. BGC 945 has low affinity for the widely expressed reduced-folate carrier (RFC). BGC 945 selectively inhibits thymidylate synthase in α-FR-overexpressing tumors and should cause minimal toxicity to humans at therapeutic doses. Synonyms: Idetrexed; ONX-0801; N-[4-[2-Propynyl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-1H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-L-γ-glutamyl-D-glutamic acid; N-[4-[2-Propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-L-γ-glutamyl-D-glutamic acid; (R) -2- ( (S) -4-carboxy-4- (4- ( ( (S) -2- (hydroxymethyl) -4-oxo-4, 6, 7, 8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl) (prop-2-yn-1-yl) amino) benzamido) butanamido) pentanedioic acid. Grades: ≥95%. CAS No. 501332-69-0. Molecular formula: C32H33N5O10. Mole weight: 647.63. | |
CB30865 Quick inquiry Where to buy Suppliers range | CB30865 is a highly potent cytotoxic agent. The compound inhibits isolated mammalian thymidylate synthase (TS), but this inhibition is insufficient to account for its cellular toxicity. Thymidylate synthase (TS) is a critical enzyme in the de novo synthesis of thymidylate (dTTP) and has long been recognized as a target for chemotherapeutic intervention. Synonyms: CB-30865; CB 30865; CB30865; ZM 242421; ZM242421; ZM-242421. Grades: >98%. CAS No. 206275-15-2. Molecular formula: C26H22BrN5O2. Mole weight: 516.39. | |
CB30900 Quick inquiry Where to buy Suppliers range | CB30900 has been found to be a thymidylate synthase inhibitor that could have some extent of activity in models with low or defective folylpolyglutamate synthetase. Synonyms: CB 30900; CB30900; CB-30900; N-(N-(4-(N-((3,4-Dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl)-N-prop-2-ynylamino)-2-fluorobenzoyl)-L-gamma-glutamyl)-D-glutamic acid. Grades: 98%. CAS No. 145788-82-5. Molecular formula: C31H32FN5O9. Mole weight: 637.61. | |
CB 3731 Quick inquiry Where to buy Suppliers range | CB 3731 can be used in fluorine-19 nuclear magnetic resonance studies of binary and ternary complexes of thymidylate synthase. Synonyms: CB 3731; CB-3731; CB3731. N-(4-((N-(2-Amino-4-hydroxy-6-quinazolinyl)methyl)-N-(fluoroethyl)amino)benzoyl)glutamic acid. Grades: 98%. CAS No. 80015-07-2. Molecular formula: C23H24FN5O6. Mole weight: 458.47. | |
dithymidine 3',5'-phosphate Quick inquiry Where to buy Suppliers range | Dithymidine 3',5'-phosphate, a biochemical of great scientific significance, features prominently in research circles as it allows the study of protein-DNA interactions and enzyme reactions. In addition, its synthesis of oligonucleotides proves instrumental in analyzing nucleic acid metabolism and DNA repair pathways. Its versatile properties make it an essential instrument of contemporary scientific pursuit. Synonyms: d(Tpt); thymidylyl(3'-5')thymidine; dTpdT DNA Dinucleotide (5'-3'). Grades: ≥95% by AX-HPLC. Molecular formula: C20H27N4O12P. Mole weight: 546.40. | |
D-Pemetrexed Dimethyl Diester Quick inquiry Where to buy Suppliers range | D-Pemetrexed dimethyl diester is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid 1,5-Dimethyl Diester. Grades: 98%. CAS No. 1391068-12-4. Molecular formula: C22H25N5O6. Mole weight: 455.46. | |
D-Pemetrexed Hydrate Quick inquiry Where to buy Suppliers range | D-Pemetrexed Hydrate is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-D-glutamic Acid Hydrate. Molecular formula: C20H23N5O7. Mole weight: 445.42. | |
Edatrexate Quick inquiry Where to buy Suppliers range | Edatrexate is a polyglutamatable folate antagonist analogue of methotrexate with antineoplastic activity. Edatrexate inhibits dihydrofolate reductase, thereby increasing cellular levels of polyglutamates, inhibiting thymidylate synthase and glycinamide ribonucleotide formyl transferase, impairing synthesis of purine nucleotides and amino acids, and resulting in tumor cell death. Edatrexate may overcome tumor resistance to methotrexate, which loses its activity after it is polyglutamated. Uses: Antineoplastic agents. Synonyms: 10-ethyl-deaza-aminopterin; 10-EDAM; 10 EDAM; 10EDAM; CGP-30694; CGP30694; CGP30694; D 03942; D-03942; D03942. CAS No. 80576-83-6. Molecular formula: C22H25N7O5. Mole weight: 467.49. | |
FdUTP Quick inquiry Where to buy Suppliers range | FdUTP, a remarkable nucleoside triphosphate, puts the brakes on thymidylate synthase, striking a fatal blow to DNA precursor synthesis and culminating in cellular collapse. This versatile substance has proven tadpole in tackling a gamut of solid tumors, from the grisly colorectal specter to the dauntingly defiant breast cancer. Synonyms: 5-Fluoro-2'-deoxyuridine-5'-triphosphate. Grades: ≥ 95 % (HPLC). Molecular formula: C9H14N2O14P3F (free acid). Mole weight: 486.1 (free acid). | |
Lufepirsen Quick inquiry Where to buy Suppliers range | Lufepirsen is a gap junction alpha-1 protein synthesis reducer. Synonyms: 2'-deoxyguanylyl-(3'?5')-thymidylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-thymidylyl-(3'?5')-thymidylyl-(3'?5')-2'-deoxyguanylyl-(3'?5')-2'-deoxycytidylyl-(3'?5')-2'-deoxyguanylyl-(3'?5')-2'-deoxyguanylyl-(3'?5')-2'-deoxycytidylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-2'-deoxyguanylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-2'-deoxyguanylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-2'-deoxyadenylyl-(3'?5')-thymidylyl-(3'?5')-thymidylyl-(3'?5')-2'-deoxyguanylyl-(3'?5')-thymidylyl-(3'?5')-thymidylyl-(3'?5')-thymidylyl-(3'?5')-2'-deoxycytidylyl-(3'?5')-thymidylyl-(3'?5')-2'-deoxyguanylyl-(3'?5')-thymidylyl-(3'?5')-2'-deoxycytidine. CAS No. 287122-58-1. Molecular formula: C296H371N112O180P29. Mole weight: 9276.09. | |
(+)-LY-338979 Quick inquiry Where to buy Suppliers range | (+)-LY-338979 is one of pemetrexed metabolites. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (S)-2-(4-(2-((S)-2-amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid; (4-(2-((S)-2-amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic acid; N-(4-{2-[(5S)-2-Amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl]ethyl}benzoyl)-L-glutamic acid; L-Glutamic acid, N-[4-[2-[(5S)-2-amino-4,5,6,7-tetrahydro-4,6-dioxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl]ethyl]benzoyl]-. Molecular formula: C20H21N5O7. Mole weight: 443.41. | |
(-)-LY-338979 Quick inquiry Where to buy Suppliers range | (-)-LY-338979 is one of pemetrexed metabolites. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (S)-2-(4-(2-((R)-2-amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid; (4-(2-((R)-2-amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic acid; N-(4-{2-[(5R)-2-Amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl]ethyl}benzoyl)-L-glutamic acid; L-Glutamic acid, N-[4-[2-[(5R)-2-amino-4,5,6,7-tetrahydro-4,6-dioxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl]ethyl]benzoyl]-. Molecular formula: C20H21N5O7. Mole weight: 443.41. | |
LY-338979 Dimethyl Ester Quick inquiry Where to buy Suppliers range | LY-338979 dimethyl ester is one of pemetrexed metabolites. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Dimethyl N-{4-[2-(2-amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamate; N-[4-[2-(2-Amino-4,5,6,7-tetrahydro-4,6-dioxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid 1,5-Dimethyl Ester; L-Glutamic acid, N-[4-[2-(2-amino-4,5,6,7-tetrahydro-4,6-dioxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, dimethyl ester. Grades: ≥95%. CAS No. 1320346-45-9. Molecular formula: C22H25N5O7. Mole weight: 471.46. | |
LY 368962 Dimethyl Ester Quick inquiry Where to buy Suppliers range | LY 368962 dimethyl ester is one of pemetrexed metabolites. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Dimethyl N-{4-[3-(2,6-diamino-4-oxo-1,4-dihydro-5-pyrimidinyl)-3-oxopropyl]benzoyl}-L-glutamate; L-Glutamic acid, N-[4-[3-(2,6-diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-3-oxopropyl]benzoyl]-, dimethyl ester; N-[4-[3-(2,6-Diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-3-oxopropyl]benzoyl]-L-glutamic Acid Dimethyl Ester; Dimethyl (4-(3-(2,6-diamino-4-oxo-1,4-dihydropyrimidin-5-yl)-3-oxopropyl)benzoyl)-L-glutamate. Grades: 98%. CAS No. 1798887-66-7. Molecular formula: C21H25N5O7. Mole weight: 459.45. | |
N-2-[(Dimethylamino)methylene]amino Pemetrexed Quick inquiry Where to buy Suppliers range | N-2-[(Dimethylamino)methylene]amino pemetrexed is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed N,N-Dimethyl Form Amide Impurity; (4-(2-(2-(((dimethylamino)methylene)amino)-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic acid. Grades: 98%. CAS No. 1265908-58-4. Molecular formula: C23H26N6O6. Mole weight: 482.49. | |
N-[4-[3-[2-Amino-4-(formylamino)-1,6-dihydro-6-oxo-5-pyrimidinyl]-3-oxopropyl]benzoyl]-L-glutamic Acid Quick inquiry Where to buy Suppliers range | N-[4-[3-[2-Amino-4-(formylamino)-1,6-dihydro-6-oxo-5-pyrimidinyl]-3-oxopropyl]benzoyl]-L-glutamic acid is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed Seco-indolone; (S)-2-(4-(3-(2-Amino-4-formamido-6-oxo-1,6-dihydropyrimidin-5-yl)-3-oxopropyl)benzamido)pentanedioic acid; Pemetrexed Impurity 20. Grades: 98%. CAS No. 1644286-35-0. Molecular formula: C20H21N5O8. Mole weight: 459.41. | |
N-Methyl Pemetrexed Quick inquiry Where to buy Suppliers range | N-Methyl Pemetrexed (Pemetrexed EP Impurity A) is an impurity of Pemetrexed, an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes. Group: Biochemicals. Alternative Names: N-[4-[2-(2-Amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid; Pemetrexed EP Impurity A. Grades: Highly Purified. CAS No. 869791-42-4. Pack Sizes: 2.5mg. Molecular Formula: C??H??N?O?, Molecular Weight: 441.44. US Biological Life Sciences. | Worldwide |
N-Methyl Pemetrexed Dimethyl Ester Quick inquiry Where to buy Suppliers range | N-Methyl pemetrexed dimethyl ester is one of pemetrexed intermediates. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed N-Methyl Dimethyl Ester; N-[4-[2-(2-Amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl] L-Glutamic Acid 1,5-Dimethyl Ester. Molecular formula: C23H27N5O6. Mole weight: 469.49. | |
N-Methyl Pemetrexed L-Glutamic Acid Quick inquiry Where to buy Suppliers range | N-Methyl Pemetrexed L-glutamic acid is one of pemetrexed intermediates. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: N-{4-[2-(2-Amino-1-methyl-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-γ-glutamyl-L-glutamic acid; L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-1-methyl-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-γ-glutamyl-. Molecular formula: C26H30N6O9. Mole weight: 570.55. | |
Nolatrexed Quick inquiry Where to buy Suppliers range | Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis. This agent also exhibits radiosensitizing activity. Uses: Antimetabolites, antineoplastic. Synonyms: 2-amino-6-methyl-5-(pyridin-4-ylthio)quinazolin-4(3H)-one; NSC648316. CAS No. 147149-76-6. Molecular formula: C14H12N4OS. Mole weight: 284.34. | |
Nolatrexed dihydrochloride Quick inquiry Where to buy Suppliers range | Nolatrexed, also known as AG337, is a thymidylate synthase inhibitor with potential anticancer activity. A phase II study of nolatrexed in 2007 in advanced HCC patients demonstrated minimal activity and significant stomatitis. Synonyms: AG 337; Thymitaq; 2-Amino-6-methyl-5-(4-pyridinylthio)-4(1H)-quinazolinone Hydrochloride; 2-amino-6-methyl-5-(pyridin-4-ylsulfanyl)-1,4-dihydroquinazolin-4-one dihydrochloride; 3,4-Dihydro-2-amino-6-methyl-4-oxo-5-(4-pyridylthio)quinazoline dihydrochloride. Grades: 98%. CAS No. 152946-68-4. Molecular formula: C14H14Cl2N4OS. Mole weight: 357.25. | |
Nolatrexed Dihydrochloride Quick inquiry Where to buy Suppliers range | Antifolate thymidylate synthase inhibitor. Antineoplastic. Group: Biochemicals. Alternative Names: 2-Amino-6-methyl-5-(4-pyridinylthio)-4(1H)-quinazolinone Hydrochloride; AG 337; Thymitaq. Grades: Highly Purified. CAS No. 152946-68-4. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
OSI-7904L Quick inquiry Where to buy Suppliers range | OSI-7904L, also known as GW1843, OVI-237, GS7904L, is a potent, 3-methyl-substituted benzoquinazoline folate analog very specific for thymidylate synthase. Uses: Antineoplastic agents. Synonyms: GS7904L; GW1843; GW 1843; GW-1843; 1843U89; OVI-237; OVI 237; OVI237. CAS No. 139987-54-5. Molecular formula: C27H24N4O6. Mole weight: 500.51. | |
PD 130883 Quick inquiry Where to buy Suppliers range | This active molecular is a potent lipophilic quinazoline antifolate and data show that marked PD130883 suppression of thymidylate synthase slows the rate but not the extent of tetrahydrofolate cofactor interconversion to dihydrofolate upon complete suppression of dihydrofolate reductase with trimetrexate. Synonyms: CHEMBL62769;123685-36-9;2-Amino-6-(((4-nitrophenyl)-2-propynylamino)methyl)-4(3H)quinazolinone;4(3H)-Quinazolinone,2-amino-6-[[(4-nitrophenyl)-2-propyn-1-ylamino]methyl]-;ACMC-20mqpf;PD-130883; PD130883; PD 130883. Grades: 95%. CAS No. 123685-36-9. Molecular formula: C18H15N5O3. Mole weight: 349.34. | |
Pemetrexed-1-methyl Ester Quick inquiry Where to buy Suppliers range | Pemetrexed-1-methyl ester is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed-1-methyl Ester; Pemetrexed Monomethyl Ester 1; SCHEMBL14331358; 1265908-61-9; (4R)-4-{[4-(2-{2-amino-4-oxo-1H,4H,7H- pyrrolo[2,3-d]pyrimidin-5-yl}ethyl)phenyl]formamido}-5-methoxy-5- oxopentanoate; Pemetrexed Impurity 1; 1265908-63-1. Grades: 98%. CAS No. 1265908-63-1. Molecular formula: C21H23N5O6. Mole weight: 441.44. | |
Pemetrexed-5-methyl Ester Quick inquiry Where to buy Suppliers range | Pemetrexed-5-methyl ester is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed Monomethyl Ester 2; 1265908-60-8; (2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]-5-methoxy-5-oxopentanoic acid; SCHEMBL15078817; (S)-2-(4-(2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanoic acid ; Pemetrexed Impurity 2; 1265908-64-2. Grades: 98%. CAS No. 1265908-64-2. Molecular formula: C21H23N5O6. Mole weight: 441.44. | |
Pemetrexed Alpha-Hydroxy Lactum Isomer II Quick inquiry Where to buy Suppliers range | Pemetrexed alpha-hydroxy lactum isomer II is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (2R)-2-(4-(2-(2-Amino-5-hydroxy-4,6-dioxo-4,5,6,7-tetrahydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic Acid. Molecular formula: C20H21N5O8. Mole weight: 459.41. | |
Pemetrexed-d5 Diethyl Ester Quick inquiry Where to buy Suppliers range | Isotope labelled Pemetrexed-d5 Diethyl Ester is an protected intermediate in the synthesis of Pemetrexed (P219500), an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes. Group: Biochemicals. Alternative Names: Diethyl 2- (4- (2- (2-Amino-4-oxo-4, 7-dihydro-3H-pyrrolo[2, 3-d]pyrimidin-5-yl) ethyl) benzamido) pentanedioate-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Pemetrexed-d5, Disodium Salt (N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid-d5 Disodium Salt) Quick inquiry Where to buy Suppliers range | Multitargeted antifolate; inhibits thymidylate synthase as well as other folate dependent enzymes. Antineoplastic. Group: Biochemicals. Alternative Names: N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid-d5 Disodium Salt. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
Pemetrexed Diethyl Ester Quick inquiry Where to buy Suppliers range | Pemetrexed diethyl ester is one of pemetrexed intermediates. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Diethyl 2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate; (S)-Diethyl 2-(4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate; N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-diethyl ester. Grades: ≥95%. CAS No. 146943-43-3. Molecular formula: C24H29N5O6. Mole weight: 483.52. | |
Pemetrexed Diethyl Ester Quick inquiry Where to buy Suppliers range | Pemetrexed Diethyl Ester is an protected intermediate in the synthesis of Pemetrexed (P219500), an multitargeted antifolate that inhibits thymidylate synthase as well as other folate dependent enzymes. Group: Biochemicals. Alternative Names: Diethyl 2- (4- (2- (2-Amino-4-oxo-4, 7-dihydro-3H-pyrrolo[2, 3-d]pyrimidin-5-yl) ethyl) benzamido) pentanedioate. Grades: Highly Purified. CAS No. 146943-43-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Pemetrexed Dimer Impurity 1 Quick inquiry Where to buy Suppliers range | Pemetrexed Dimer Impurity 1 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C43H46N10O15. Mole weight: 942.88. | |
Pemetrexed Disodium Heptahydrate Quick inquiry Where to buy Suppliers range | Pemetrexed disodium is an chemotherapy drug identified as a highly efficient substrate for folylpolyglutamate synthase, potently inhibits multiple folate-dependent enzymes involved in both purine and pyrimidine synthesis including thymidylate synthase (Ki = 109 nM). Uses: A novel antifolate and antimetabolite for ts, dhfr and garft with ki of 1.3 nm, 7.2 nm and 65 nm, respectively. Synonyms: N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium Salt Heptahydrate; Pemetrexed (sodium salt hydrate); L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-8 oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, disodium salt, heptahydrate. Grades: > 98%. CAS No. 357166-29-1. Molecular formula: C20H33N5Na2O13. Mole weight: 597.48. | |
Pemetrexed, Disodium Salt, Heptahydrate (N-[4-[(2-Amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic Acid Disodium, LY-231514, Alimta) Quick inquiry Where to buy Suppliers range | Pemetrexed inhibits dihydrofolate reductase, thymidylate synthase and glycinamide ribonucleotide formyltransferase with Ki values of 7nM, 109nM and 9.3uM, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 357166-29-1. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
Pemetrexed EP Impurity B Quick inquiry Where to buy Suppliers range | Pemetrexed EP Impurity B is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: (R)-Pemetrexed EP Isomer; (2S, 2'S)-2, 2'- ( (4, 4'- ( ( (R)-2, 2'-Diamino-4, 4', 6-trioxo-4, 4', 5, 6, 7, 7'-hexahydro-1H, 1'H-[5, 6'-bipyrrolo[2, 3-d]pyrimidine]-5, 5'-diyl)bis (ethane-2, 1-diyl))bis (benzoyl))bis (azanediyl))dipentanedioic Acid. Grades: > 98%. CAS No. 1802552-04-0. Molecular formula: C40H40N10O13. Mole weight: 868.80. | |
Pemetrexed Impurity 19 Quick inquiry Where to buy Suppliers range | Pemetrexed Impurity 19 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C25H28N6O9. Mole weight: 556.52. | |
Pemetrexed Impurity 25 Quick inquiry Where to buy Suppliers range | Pemetrexed Impurity 25 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C8H10N4O4. Mole weight: 226.19. | |
Pemetrexed Impurity 26 Quick inquiry Where to buy Suppliers range | Pemetrexed Impurity 26 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C14H15N5O3. Mole weight: 301.30. | |
Pemetrexed Impurity 27 Quick inquiry Where to buy Suppliers range | Pemetrexed Impurity 27 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C15H15N5O4. Mole weight: 329.31. | |
Pemetrexed Impurity 28 Quick inquiry Where to buy Suppliers range | Pemetrexed Impurity 28 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Synonyms: Pemetrexed Impurity 24. Molecular formula: C20H21N5O8. Mole weight: 459.41. | |
Pemetrexed Impurity 29 Quick inquiry Where to buy Suppliers range | Pemetrexed Impurity 29 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H21N5O8. Mole weight: 459.41. | |
Pemetrexed Impurity 3 Quick inquiry Where to buy Suppliers range | An impurity of Pemetrexed which binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Grades: > 95%. CAS No. 229470-22-8. Molecular formula: C17H21N5O5. Mole weight: 375.39. | |
Pemetrexed Impurity 30 Quick inquiry Where to buy Suppliers range | Pemetrexed Impurity 30 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C31H40N6O9. Mole weight: 640.68. | |
Pemetrexed Impurity 31 Quick inquiry Where to buy Suppliers range | Pemetrexed Impurity 31 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C27H34N6O6. Mole weight: 538.59. | |
Pemetrexed Impurity 32 Quick inquiry Where to buy Suppliers range | Pemetrexed Impurity 32 is one of pemetrexed impurities. Pemetrexed binds to and inhibits the enzyme thymidylate synthase (TS) which catalyses the methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP), an essential precursor in DNA synthesis. Molecular formula: C20H21N5O8. Mole weight: 459.41. |