Trans Retinoic Suppliers USA
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Product | Description | |
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4-Hydroxy-all-trans-Retinoic Acid Quick inquiry Where to buy Suppliers range | 4-Hydroxy-all-trans-Retinoic Acid is a metabolite of all-trans Retinoic acid. All-trans Retinoic acid is a metabolite of Vitamin A and ajusts its functions of cellular growth and differentiation. Synonyms: rac all-trans 4-Hydroxy Retinoic Acid; 4-Hydroxyretinoic Acid. CAS No. 66592-72-1. Molecular formula: C20H28O3. Mole weight: 316.44. | |
4-Keto all-trans-Retinoic Acid (4-Keto-Tretinoin) Quick inquiry Where to buy Suppliers range | A metabolite of all-trans-Retinoic Acid, a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). Group: Biochemicals. Alternative Names: 4-Keto-Tretinoin. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
4-Keto all-trans-Retinoic acid Methyl Ester Quick inquiry Where to buy Suppliers range | 4-Keto all-trans-Retinoic acid Methyl Ester. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
4-Keto all-trans-Retinoic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 4-Keto all-trans-Retinoic Acid Methyl Ester is a derivative of Retinoic acid. Retinoic Acid is a metabolite of Vitamin A and ajusts its functions of cellular growth and differentiation. Synonyms: 4-Oxoretinoic Acid Methyl Ester; Methyl 4-Ketoretinoate; Methyl 4-Oxoretinoate. Grades: ≥95%. CAS No. 38030-58-9. Molecular formula: C21H28O3. Mole weight: 328.44. | |
5,6-Epoxy-all-trans-Retinoic Acid Quick inquiry Where to buy Suppliers range | 5,6-Epoxy-all-trans-Retinoic Acid is a metabolite of all-trans Retinoic acid. All-trans Retinoic acid is a metabolite of Vitamin A and ajusts its functions of cellular growth and differentiation. Synonyms: all-trans 5,6-Epoxy Retinoic Acid; 5,6-Epoxyretinoic Acid; 2,4,6,8-Nonatetraenoic acid, 3,7-dimethyl-9-(2,2,6-trimethyl-7-oxabicyclo[4.1.0]hept-1-yl)-, (2E,4E,6E,8E)-; 5,6-Epoxy-5,6-dihydroretinoic acid. Grades: ≥95%. CAS No. 13100-69-1. Molecular formula: C20H28O3. Mole weight: 316.43. | |
All-trans retinoic acid Quick inquiry Where to buy Suppliers range | All-trans retinoic acid. CAS No: 302-79-4 | Sarchem Laboratories New Jersey NJ |
ALL-TRANS RETINOIC ACID Quick inquiry Where to buy Suppliers range | ALL TRANS RETINOIC ACID. CAS No. 302-79-4. | |
all-trans Retinoic Acid-d5 Ethyl Ester (3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic Acid-d5 Ethyl Ester, (E)-Ethyl Retinoate-d5) Quick inquiry Where to buy Suppliers range | Retinoic acid derivative. Group: Biochemicals. Alternative Names: 3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic Acid-d5 Ethyl Ester; (E)-Ethyl Retinoate-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
all-trans-Retinoic acid methyl ester Quick inquiry Where to buy Suppliers range | all-trans-Retinoic acid methyl ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 339-16-2. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C21H30O2. US Biological Life Sciences. | Worldwide |
all-trans Retinoic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | all-trans Retinoic Acid Methyl Ester. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
all-trans-18-Hydroxy Retinoic Acid Quick inquiry Where to buy Suppliers range | all-trans-18-Hydroxy Retinoic Acid is a hydroxylated metabolite of all-trans-Retinoic Acid. Synonyms: 18-Hydroxy-all-trans-retinoic acid; 18-Hydroxyretinoic acid; Ro 12-4825; 2,4,6,8-Nonatetraenoic acid, 3,7-dimethyl-9-(6,6-dimethyl-2-(hydroxymethyl)-1-cyclohexen-1-yl)-, (E)-; all-trans-9-(2-(Hydroxymethyl)-6,6-dimethyl-1-cyclohexen-1-yl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid. Grades: ≥95%. CAS No. 63531-93-1. Molecular formula: C20H28O3. Mole weight: 316.43. | |
all-trans 4-Keto retinoic acid Quick inquiry Where to buy Suppliers range | all-trans 4-Keto retinoic acid. Group: Biochemicals. Alternative Names: 4-Oxoretinoic acid; 4-Ketoretinoic acid; 4-Oxo-all-trans-retinoic acid. Grades: Highly Purified. CAS No. 38030-57-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C20H26O3. US Biological Life Sciences. | Worldwide |
all-trans 4-Keto Retinoic Acid-(9-methyl)-d3 Quick inquiry Where to buy Suppliers range | A deuterated metabolite of all-trans-Retinoic Acid, a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). Group: Biochemicals. Alternative Names: 4-Oxoretinoic Acid-7-d3; 4-Ketoretinoic Acid-7-d3; 4-Oxo-all-trans-retinoic Acid-7-d3; 4-Oxo-atRA-7-d3; 4-Oxotretinoin-d3; 4-keto-Retinoic Acid-7-d3; Ro 11-4824-7-d3; Ro 12-4824-7-d3; all-trans-4-Oxoretinoic Acid-7-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
rac all-trans 3-Hydroxy Retinoic Acid Ethyl Ester Quick inquiry Where to buy Suppliers range | rac all-trans 3-Hydroxy Retinoic Acid Ethyl Ester is a derivative of all-trans Retinoic acid. Retinoic Acid is a metabolite of Vitamin A and ajusts its functions of cellular growth and differentiation. Synonyms: (±)-3-Hydroxy-retinoic Acid Ethyl Ester; Retinoic acid, 3-hydroxy-, ethyl ester, (±)-. Grades: ≥95%. CAS No. 120674-74-0. Molecular formula: C22H32O3. Mole weight: 344.49. | |
rac all-trans 3-Hydroxy Retinoic Acid Ethyl Ester Quick inquiry Where to buy Suppliers range | all-trans Retinoic acid derivative. Group: Biochemicals. Alternative Names: (±)-3-Hydroxy-retinoic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 120674-74-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
all-trans-3,4-Didehydro retinoic acid Quick inquiry Where to buy Suppliers range | all-trans-3,4-Didehydro retinoic acid. Group: Biochemicals. Alternative Names: (all-E)-3,7-dimethyl-9-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-2,4,6,8-nonatetraenoic acid; 3-Dehydroretinoic acid. Grades: Highly Purified. CAS No. 4159-20-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C20H26O2. US Biological Life Sciences. | Worldwide |
all-trans-3,4-Didehydro Retinoic Acid Quick inquiry Where to buy Suppliers range | all-trans-3,4-Didehydro Retinoic Acid is a Retinoic Acid derivative for the treatment of neuroinflammatory conditions. Synonyms: (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-2,4,6,8-nonatetraenoic Acid; 3-Dehydroretinoic Acid; 3,4-Didehydro-all-trans-retinoic Acid; 3,4-Didehydroretinoic Acid; Ro 8-7057; Vitamin A2 Acid; all-trans-Vitamin A2 Acid; all-trans-Vitamin A2 Acid. Grades: 96%. CAS No. 4159-20-0. Molecular formula: C20H26O2. Mole weight: 298.42. | |
all-trans 5,6-Epoxy Retinoic Acid Quick inquiry Where to buy Suppliers range | A metabolite of all-trans Retinoic acid. Group: Biochemicals. Alternative Names: 5,6-Epoxy-5,6-dihydroretinoic Acid; 5,6-Epoxyretinoic Acid. Grades: Highly Purified. CAS No. 13100-69-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
all-trans 5,8-Epoxy Retinoic Acid (Mixture of Diastereomers) Quick inquiry Where to buy Suppliers range | A metabolite of all-trans Retinoic acid. Group: Biochemicals. Alternative Names: (2E,4E,6E)-7-(2,4,5,6,7,7a-Hexahydro-4,4,7a-trimethyl-2-benzofuranyl)-3-methyl-2,4,6-octatrienoic Acid. Grades: Highly Purified. CAS No. 3012-76-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
rac all-trans-13,14-Dihydro Retinoic Acid Ethyl Ester Quick inquiry Where to buy Suppliers range | rac all-trans-13,14-Dihydro Retinoic Acid Ethyl Ester is a dihydro ester derivative of all-trans Retinoic Acid. Synonyms: ethyl (4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-4,6,8-trienoate; Ethyl all-trans-13,14-Dihydro Retinoate. Molecular formula: C22H34O2. Mole weight: 330.50. | |
(11-cis,13-cis)-4-Oxoretinoic Acid Quick inquiry Where to buy Suppliers range | (11-cis,13-cis)-4-Oxoretinoic Acid is an intermediate in the synthesis of all-trans 4-Keto Retinoic Acid (K204980), a metabolite of all-trans-Retinoic Acid, a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). Group: Biochemicals. Grades: Highly Purified. CAS No. 112924-95-5. Pack Sizes: 1mg, 10mg. Molecular Formula: C20H26O3, Molecular Weight: 314.42. US Biological Life Sciences. | Worldwide |
13-cis-Retinonitrile-13C2 Quick inquiry Where to buy Suppliers range | An isomer of a labeled all-trans-Retinal intermediate. Group: Biochemicals. Alternative Names: (2E,4E,6E,8Z)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenenitrile-13C2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
(1S,2S)-N-[4-[2-(Dimethylamino)-1-(1H-imidazol-1-yl)]propylphenyl]-2-benzothiazolamine Quick inquiry Where to buy Suppliers range | (1S,2S)-N-[4-[2-(Dimethylamino)-1-(1H-imidazol-1-yl)]propylphenyl]-2-benzothiazolamine is an inhibitor of the P450 system, which consists of enzymes involved in the electron transport chain. (1S,2S)-N-[4-[2-(Dimethylamino)-1-(1H-imidazol-1-yl)]propylphenyl]-2-benzothiazolamine is also a potent and selective inhibitor of the all-trans-retinoic acid metabolism. Group: Biochemicals. Grades: Highly Purified. CAS No. 355860-40-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C21H23N5S, Molecular Weight: 377.51. US Biological Life Sciences. | Worldwide |
2,2-Dimethylcyclohexanone Quick inquiry Where to buy Suppliers range | 2,2-Dimethylcyclohexanone is a useful synthetic intermediate. It is used as a reagent to prepare 9-cis-retinoic acid ring-demethylated analogs. It is also used to prepare selective Janus kinase inhibitors for the treatment of autoimmune diseases and organ transplant rejection. Group: Biochemicals. Grades: Highly Purified. CAS No. 1193-47-1. Pack Sizes: 250mg, 1g. Molecular Formula: C8H14O. US Biological Life Sciences. | Worldwide |
(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-3-oxo-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid Quick inquiry Where to buy Suppliers range | (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-3-oxo-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid. Group: Main Products. Alternative Names: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxo-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid;4-oxo-Retinoic acid;all-trans 4-Keto Retinoic Acid;(E)-3,7-Dimethyl-9-(2,6,6-trimethyl-3-oxo-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid;4-Ketoretinoic acid;4-Oxo-all-trans-retinoic acid;Retinoic acid, 4-oxo-;Ro 12-4824. Grades: 98%. CAS No. 38030-57-8. Molecular formula: C20H26O3. Mole weight: 0. IUPAC Name: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxocyclohexen-1-yl)nona-2,4,6,8-tetraenoicacid. Exact Mass: 314.18800. Boiling Point: 509.9ºC at 760 mmHg. Melting Point: 175-178°C (dec.). Flash Point: 276.3ºC. Density: 1.07g/cm3. SMILES: CC1=C (C (CCC1=O) (C)C)C=CC (=CC=CC (=CC (=O)O)C)C. InChIKey: GGCUJPCCTQNTJF-FRCNGJHJSA-N. | |
3-Dehydro Retinol Quick inquiry Where to buy Suppliers range | Naturally occurring retinoid originally discovered in livers of freshwater fish. Constitutes 20-25% of total retinoid content in human epidermis; levels are markedly elevated in patients with hyperproliferative dermatoses such as psoriasis. Group: Biochemicals. Alternative Names: (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1,3-cyclohexadien-1-yl)-2,4,6,8-nonatetraen-1-ol; 3,4-Dehydroretinol;all-trans- 3-Dehydroretinol; Dehydroretinol; Vitamin A2; all-trans-3,4-Didehydroretinol. Grades: Highly Purified. CAS No. 79-80-1. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
4-Keto Retinal Quick inquiry Where to buy Suppliers range | . Uses: An inactive catabolite of retinoic acid. Synonyms: (2E,4E,6E,8E)-9-(2,6,6-Trimethyl-3-keto-1-cyclohexen-1-yl)-3,7-dimethyl-2,4,6,8-nonatetraen-1-al; 4-Oxo-all-trans-retinal; 4-Oxoretinal; all-trans-4-Oxoretinal. Grades: 96%. CAS No. 33532-44-4. Molecular formula: C20H26O2. Mole weight: 298.42. | |
4-KETORETINOL Quick inquiry Where to buy Suppliers range | 4-Oxoretinol, 4-Ketoretinol, 62702-55-0, 4-Keto Retinol, all-trans-4-oxoretinol, 6FFM6M3NPT, 3-[(1E,3E,5E,7E)-9-hydroxy-3,7-dimethylnona-1,3,5,7-tetraenyl]-2,4,4-trimethylcyclohex-2-en-1-one, OXR, 4-oxoROL, 4-Keto Retinol (~90%), 4-oxo-Retinol, 4-oxovitamin A1, Retinol, 4-oxo-, 4-oxo-ROL, 4-ketovitamin A(1), 4-oxovitamin-A-alcohol, 4-ketovitamin-A-alcohol, UNII-6FFM6M3NPT, 4-oxovitamin-alpha-alcohol, 4-ketovitamin-alpha-alcohol, 4OVA1, SCHEMBL1598556, CHEBI:44597, DTXSID80866949, RETIN-4-ONE, 15-HYDROXY-, DB02699, Q27093646, 3,7-dimethyl-9-(3-oxo-2,6,6-trimethyl-1-cyclohexenyl)-2,4,6,8-nonatetraen-1-ol, 3-((1E,3E,5E,7E)-9-Hydroxy-3,7-dimethylnona-1,3,5,7-tetraen-1-yl)-2,4,4-trimethylcyclohex-2-enone, 3-((1E,3E,5E,7E)-9-hydroxy-3,7-dimethylnona-1,3,5,7-tetraenyl)-2,4,4-trimethylcyclohex-2-enone, 3-[(1E,3E,5E,7E)-9-hydroxy-3,7-dimethylnona-1,3,5,7-tetraen-1-yl]-2,4,4-trimethylcyclohex-2-en-1-one. | |
4-Methoxy Retinoic Acid Quick inquiry Where to buy Suppliers range | 4-Methoxy Retinoic Acid is an impurity of Retinoic acid. Retinoic Acid is a metabolite of Vitamin A and ajusts its functions of cellular growth and differentiation. Uses: An impurity contained in samples of all trans-retinoic acid. Synonyms: (+/-)-4-Methoxyretinoic Acid. Grades: 95%. CAS No. 81121-20-2. Molecular formula: C21H30O3. Mole weight: 330.46. | |
4-Methoxy Retinoic Acid Quick inquiry Where to buy Suppliers range | An impurity contained in samples of all trans-retinoic acid. Group: Biochemicals. Alternative Names: (+/-)-4-Methoxyretinoic Acid. Grades: Highly Purified. CAS No. 81121-20-2. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
4-Methoxy Retinoic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | all-trans Retinoic Acid impurity. Group: Biochemicals. Alternative Names: (+/-)-4-Methoxyretinoic Acid. Grades: Highly Purified. CAS No. 163808-81-9. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
5,8-Monoepoxyretinoic Acid Quick inquiry Where to buy Suppliers range | 5,8-Epoxy-all-trans-Retinoic Acid (Mixture of Diastereomers) is a metabolite of all-trans Retinoic acid. All-trans Retinoic acid is a metabolite of Vitamin A and ajusts its functions of cellular growth and differentiation. Synonyms: 5,8-Epoxyretinoic Acid; 5,8-Epoxy-5,8-dihydroretinoic Acid; (2E,4E,6E)-7-(2,4,5,6,7,7a-hexahydro-4,4,7a-trimethyl-2-benzofuranyl)-3-methyl-2,4,6-octatrienoic Acid. Grades: ≥95%. CAS No. 3012-76-8. Molecular formula: C20H28O3. Mole weight: 316.43. | |
9,13-Di-cis-retinoic Acid Quick inquiry Where to buy Suppliers range | 9,13-Di-cis-retinoic Acid is a metabolite of 9-cis Retinoic Acid that induces liver fibrosis through activating transforming growth factor-&beta. Synonyms: (9-cis,13-cis)-Retinoic Acid; (2Z,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenoic acid; Isotretinoin EP Impurity B. CAS No. 5352-74-9. Molecular formula: C20H28O2. Mole weight: 300.44. | |
9-cis-Retinoic Acid Quick inquiry Where to buy Suppliers range | ≥98% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy; Pharmaceutical Toxicology. Alternative Names: LG 100057, LGD 1057, Toctino, LGD 100057, Panretin, 9-cis-Tretinoin,9-cis-Retinoic Acid, Retinoic acid, cis-9,trans-13- (8CI), Alitretinoin, Panretyn, AGN 192013, ALRT 1057, Panrexin, NSC 659772, 9(Z)-Retinoic acid, 9-cis-Retinoic acid. CAS No. 5300-3-8. Pack Sizes: 1MG. IUPAC Name: (2E,4E,6Z,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid. Molecular formula: C20H28O2. Mole weight: 300.44. Catalog: APS5300038. Assay: ≥98% (HPLC). SMILES: C\C (=C\C=C\C (=C\C (=O)O)\C)\C=C\C1=C (C)CCCC1 (C)C. Format: Neat. | |
A 1120 Quick inquiry Where to buy Suppliers range | A 1120 is a retinol-binding protein 4 (RBP4) antagonist (Ki = 8.3 nM) that can reduce serum RBP4 and retinol, and displaces transthyretin (TTR) from RBP4-TTR complexes. Synonyms: A-1120; A1120; 2-(4-(2-(Trifluoromethyl)phenyl)piperidine-1-carboxamido)benzoic acid. Grades: ≥99% by HPLC. CAS No. 1152782-19-8. Molecular formula: C20H19F3N2O3. Mole weight: 392.37. | |
AGN 194310 Quick inquiry Where to buy Suppliers range | A high affinity pan-RAR antagonist (AGN194310, K(d) for binding to RARs = 2-5 nM) inhibited colony formation (by 50%) by all three lines at 16-34 nM, and led to a transient accumulation of flask-cultured cells in G1 followed by apoptosis. AGN194310 is 12-22 fold more potent than all-trans retinoic acid (ATRA) against cell lines and also more potent in inhibiting the growth of primary prostate carcinoma cells. The administration of all-trans retinoic acid to VAD mice resulted in a transient reduction in NF-kappaB activity and, conversely, a single dose of the RAR-pan-antagonist, AGN 194310, administered to control mice, led to a marked, transient induction of whole-body luminescence. Mice were treated with AGN194310, a synthetic retinoid that antagonises the physiological function of the three RAR isotypes (alpha, beta, gamma) but does not interact with RXRs. Analyses of the granulocytic lineage using Gr-1, c-Kit and CD11b antibodies, demonstrated that granulocyte numbers were strikingly increased across haemopoietic compartments in all AGN194310-treated mice. A significant increase in the frequency of progenitor cells containing granulocytes was observed in the bone marrow of mice following treatment with AGN194310. Synonyms: AGN194310; AGN-194310; VTP194310; VTP 194310; VTP-194310. Grades: >98%. CAS No. 229961-45-9. Molecular formula: C28H24O2S. Mole weight: 424.55. | |
AGN 196996 Quick inquiry Where to buy Suppliers range | AGN 196996 is a potent and selective antagonist of RAR&alpha. It has been reported to selectively bind to RARs (retinoic acid receptors) for RARα, RARβ and RAR&gamma. It can inhibit the gene transcription activity which induced by ATRA and other RAR agonists. It shows no activity in transactivation assays, but instead block the gene transcriptional activity induced by ATRA and other RAR agonists. Grades: >98%. CAS No. 958295-17-5. Molecular formula: C24H20BrNO5. Mole weight: 482.32. | |
all-trans Acitretin-d3 ((all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic Acid-d3, Neotigason-d3, Soriatane-d3) Quick inquiry Where to buy Suppliers range | A synthetic retinoid which is the major metabolite of etretinate. Group: Biochemicals. Alternative Names: (all-E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic Acid-d3; Neotigason-d3; Soriatane-d3. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
all-trans-Anhydro retinol Quick inquiry Where to buy Suppliers range | all-trans-Anhydro retinol. Group: Biochemicals. Alternative Names: (6E)-6-[(2E,4E,6E)-3,7-Dimethyl-2,4,6,8-nonatetraen-1-ylidene]-1,5,5-trimethylcyclohexene. Grades: Highly Purified. CAS No. 1224-78-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C20H28. US Biological Life Sciences. | Worldwide |
all trans-Retinal Quick inquiry Where to buy Suppliers range | All-trans retinal is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Synonyms: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenal. Grades: > 95 %. CAS No. 116-31-4. Molecular formula: C20H28O. Mole weight: 284.44. | |
all-trans Retinal (Vitamin A Aldehyde, Retinene, Retinylaldehyde) Quick inquiry Where to buy Suppliers range | Corotenoid component of the visual pigments. All-trans retinal is converted to retinoic acid in vivo by the action of retinal dehydrogenase. Group: Biochemicals. Alternative Names: (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenal; all -trans-Vitamin A Aldehyde; Retinene; Retinylaldehyde. Grades: Highly Purified. CAS No. 116-31-4. Pack Sizes: 500mg, 1g. US Biological Life Sciences. | Worldwide |
all-trans-Retinol Quick inquiry Where to buy Suppliers range | Phytochemicals. Uses: For analytical and research use. Group: reagents. CAS No. 68-26-8. IUPAC Name: (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol. | |
all-trans-Retinol Quick inquiry Where to buy Suppliers range | all-trans-Retinol. Group: Biochemicals. Alternative Names: (all-E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol; A-Mulsal; A-Sol. Grades: Highly Purified. CAS No. 68-26-8. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C20H30O. US Biological Life Sciences. | Worldwide |
All-trans Retinol Quick inquiry Where to buy Suppliers range | Vitamin A is a group of unsaturated nutritional organic compounds, which includes retinol, retinal, retinoic acid, several provitamin A carotenoids, and beta-carotene. Vitamin A is important for growth and development, for the maintenance of the immune system and good vision. Vitamin A is needed by the retina of the eye in the form of retinal, which combines with protein opsin to form rhodopsin, the light-absorbing molecule necessary for both low-light (scotopic vision) and color vision. Vitamin A also functions in a very different role as retinoic acid (an irreversibly oxidized form of retinol), which is an important hormone-like growth factor for epithelial and other cells. Uses: Vitamin a is indicated only for prevention or treatment of vitamin a deficiency states. Synonyms: Vitamin A; Vitamin A1; (all-e)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol; 2,4,6,8-Nonatetraen-1-ol, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-; 21 CFR 182,5930; 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclchexen-1-yl)-2,4,6,8-nonate. Grades: >98%. CAS No. 68-26-8. Molecular formula: C20H30O. Mole weight: 286.46. | |
ALL-TRANS RETINOL Quick inquiry Where to buy Suppliers range | ALL TRANS RETINOL. CAS No. 68-26-8. | |
all-trans Retinol (Vitamin A) Quick inquiry Where to buy Suppliers range | Atmosphere: Group: Biochemicals. Alternative Names: Vitamin A. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
All-trans-Retinol (Vitamin A Alcohol) Quick inquiry Where to buy Suppliers range | 1g Pack Size. Group: Aroma Chemicals, Biochemicals, Building Blocks. Formula: C20H30O. CAS No. 68-26-8. Prepack ID 25998401-1g. Molecular Weight 286.45. See USA prepack pricing. | |
All-trans-Retinol (Vitamin A Alcohol) Quick inquiry Where to buy Suppliers range | 100mg Pack Size. Group: Aroma Chemicals, Biochemicals, Building Blocks. Formula: C20H30O. CAS No. 68-26-8. Prepack ID 25998401-100mg. Molecular Weight 286.45. See USA prepack pricing. | |
all-trans-Retinonitrile Quick inquiry Where to buy Suppliers range | all-trans-Retinonitrile. Group: Biochemicals. Alternative Names: (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenenitrile; all-trans-vitamin A nitrile. Grades: Highly Purified. CAS No. 20638-88-4. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C20H27N. US Biological Life Sciences. | Worldwide |
all-trans-Retinonitrile-14,15-13C2 Quick inquiry Where to buy Suppliers range | Labeled Retinal intermediate. Group: Biochemicals. Alternative Names: (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenenitrile-14,15-13C2; all-trans-Vitamin A Nitrile-14,15-13C2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
all-trans-Retinoyl Fluoride Quick inquiry Where to buy Suppliers range | all-trans-Retinoyl Fluoride is an intermediate used in the synthesis of all-trans Retinoyl β-D-Glucuronide, which is a biliary metabolite of Vitamin A. Synonyms: Retinoyl Fluoride; 15-Fluororetinal; Retinoyl fluoride (all-trans); (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoyl fluoride. CAS No. 83802-77-1. Molecular formula: C20H27FO. Mole weight: 302.43. | |
Bexarotene (4-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoic Acid) Quick inquiry Where to buy Suppliers range | A retinoid X receptor (RXR) agonist that can permeate the blood-brain barrier and rapidly reduce AB40 and AB42 levels in APP/PS1 mice in an ApoE-dependent manner (25% reduction in 6h and 50% reduction in 72h). Causes a rapid reversal of cognitive, social, and olfactory deficts. Shown to progressively enhance the expression of ApoE and ATP-binding cassette transporters ABCA1 and ABCG1. Also stimulates the secretion of highly lapidated HDL particles in primary microglia and astrocytes. Does not affect the levels of AB proteases, insulin degrading enzyme, and neprilysin. Group: Biochemicals. Grades: Highly Purified. CAS No. 153559-49-0. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
BMS 453 Quick inquiry Where to buy Suppliers range | BMS 453 is a synthetic retinoid that acts as an RARβ agonist in vivo, and also an RARα and RARγ antagonist in vitro. It inhibits the proliferation of breast cells by inducing active transforming growth factor β (TGFβ) and causes G1 arrest. Synonyms: BMS453; BMS 453; BMS-453; BMS 189453; BMS-189453; BMS189453. 4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid. Grades: ≥98% by HPLC. CAS No. 166977-43-1. Molecular formula: C27H24O2. Mole weight: 380.48. | |
CD1530 Quick inquiry Where to buy Suppliers range | CD1530 is a potent and selective retinoic acid receptor(RAR) agonist with Ki values of 150, 1500 and 2750 nM for RARγ, RARβ and RARα receptors respectively. It was also a potent CYP26A1 inhibitor as ketoconazole with an IC50 value of 530 nM. It inhibited excessive ROS production in tongue epithelial cells in vitro. It demonstrates transcriptional activity at RARγ with an AC50 value of 1.8 nM. It has been shown to preserve human tendon stem cell characteristics, promote repair of injured skeletal muscle, and in combination with bexarotene to inhibit oral carcinogenesis. Synonyms: 4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid; CD 1530; CD-1530; Benzoic acid, 4-(6-hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)-; 4-[7-(Adamantan-1-yl)-6-hydroxy-2-naphthyl]benzoic acid. Grades: ≥95%. CAS No. 107430-66-0. Molecular formula: C27H26O3. Mole weight: 398.49. | |
dl-α-Tocopheryl Retinoate Quick inquiry Where to buy Suppliers range | dl-α-Tocopheryl Retinoate is an α-tocopherol ester of all-trans retinoic acid. Synonyms: Retinoic acid, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl ester, (±)-; (2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl (±)-retinoate; Retinoic acid, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R*(4R*,8R*)]-(±)-; L 300; N 021; Olcenon; Tocoretinate; Tretinoin tocoferil. Grades: 95%. CAS No. 40516-48-1. Molecular formula: C49H76O3. Mole weight: 713.12. | |
E-Retinyl b-glucuronide Quick inquiry Where to buy Suppliers range | E-Retinyl b-glucuronide is a biomedical compound, used for studying retinal diseases. Derived from retinol, this compound is indispensable in preserving visual acuity and upholding retinal well-being. Synonyms: all-trans-Retinyl b-glucuronide. CAS No. 16639-19-3. Molecular formula: C26H38O7. Mole weight: 462.58. | |
HMTase Inhibitor IX, MM-102 (Histone Methyltransferase Inhibitor IX, MM102, (S) -N- (bis (4-Fluoro phenyl ) methy l )-1- (2- (2-ethyl -2-isobutyramidobutanamid o)-5-guanidinopentanamido) cyclopentane carboxami de , TFA) Quick inquiry Where to buy Suppliers range | A cell-permeable peptidomimetic that prevents MLL1 (Mixed Lineage Leukemia 1) from complex assembling with WDR5 (Trp-Asp Repeat Domain 5), RbBP5 (Retinoblastoma Binding Protein 5), and ASH2L (Absent Small or Homeotic-2-Like) for enhanced H3K4 methyltransferase activity (IC50 = 0.4nM). Shown to reduce HoxA9 and Meis-1 mRNA expression in myeloblasts derived from MLL1-AF9-transduced murine bone marrow cells (50uM for 96 h) and preferentially inhibit the growth of MLL1-AF4-harboring MV4;11 and MLL1-ENL-harboring KOPN8 leukemia cultures (GI50 in 7 days = 25uM) via apoptosis induction, while exhibiting much reduced potency against BCR-ABL-dependent K562 cells (GI50 in 7 days = 84uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??F?N?O? · CF?CO?H. US Biological Life Sciences. | Worldwide |
HX 531 Quick inquiry Where to buy Suppliers range | HX 531 is a potent RXR antagonist (IC50 = 18 nM) that inhibits 9-cis retinoic acid-induced transactivation of RXR. HX 531 promotes the differentiation of white and brown pre-adipocyte to white adipocytes, and reduces triglyceride content in white adipose tissue, skeletal muscle, and the liver of mice given a high fat diet. Synonyms: HX 531; HX-531; HX531. 4-(7,8,9,10-Tetrahydro-5,7,7,10.10-pentamethyl-2-nitro-5H-benzo[b]naphtho[2,3-e][1,4]-diazepin-12-yl)-benzoic acid. Grades: ≥98% by HPLC. CAS No. 188844-34-0. Molecular formula: C29H29N3O4. Mole weight: 483.56. | |
Hydroxypinacolone retinoate Quick inquiry Where to buy Suppliers range | Hydroxypinacolone retinoate. Uses: Use as antioxidant. Alternative Names: Retinoic acid, 1-hydroxy-3,3-diemthyl-2-butanone ester, all-trans. CAS No. 893412-73-2. Product ID: ACM893412732-1. Molecular formula: C26H38O3. Mole weight: 398.58. | |
LEE011 hydrochloride Quick inquiry Where to buy Suppliers range | CDK4/6 inhibitor LEE011 specifically inhibits CDK4 and 6, thereby inhibiting retinoblastoma (Rb) protein phosphorylation. Inhibition of Rb phosphorylation prevents CDK-mediated G1-S phase transition, thereby arresting the cell cycle in the G1 phase, suppressing DNA synthesis and inhibiting cancer cell growth. Overexpression of CDK4/6, as seen in certain types of cancer, causes cell cycle deregulation.Treatment with LEE011 significantly reduced proliferation in 12 of 17 human neuroblastoma-derived cell lines by inducing cytostasis at nanomolar concentrations (mean IC50 = 307 ± 68 nmol/L in sensitive lines). LEE011 caused cell-cycle arrest and cellular senescence that was attributed to dose-dependent decreases in phosphorylated RB and FOXM1, respectively. Responsiveness of neuroblastoma xenografts to LEE011 translated to the in vivo setting in that there was a direct correlation of in vitro IC50 values with degree of subcutaneous xenograft growth delay. Synonyms: 7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide hydrochloride; Ribociclib hydrochloride; LEE011; LEE-011 LEE 011. Grades: >98%. CAS No. 1211443-80-9. Molecular formula: C23H31ClN8O. Mole weight: 471.0. | |
Liarozole hydrochloride Quick inquiry Where to buy Suppliers range | Liarozole is a benzimidazole derivative with potential antineoplastic activity. As a retinoic acid metabolism blocking agent (RAMBA), liarozole inhibits cytochrome P450-dependent all-trans-retinoic acid (ATRA)-4-hydroxylase, resulting in an increase in endogenous ATRA production, inhibition of cell proliferation, and induction of cell differentiation. This agent also inhibits aromatase, the enzyme that catalyzes the final, rate-limiting step in estrogen biosynthesis. Synonyms: Liarozole HCl; R75251 (hydrochloride); 5-((3-chlorophenyl)(1H-imidazol-1-yl)methyl)-1H-benzo[d]imidazole hydrochloride. CAS No. 145858-50-0. Molecular formula: C17H14Cl2N4. Mole weight: 345.23. | |
Melanoma antigen preferentially expressed in tumors (100-108) Quick inquiry Where to buy Suppliers range | Melanoma antigen preferentially expressed in tumors (100-108) is a bioactive peptide of Melanoma antigen preferentially expressed in tumors. Melanoma antigen preferentially expressed in tumors inhibits the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG as a transcriptional repressor. Synonyms: Opa-interacting protein 4 (100-108); Preferentially expressed antigen of melanoma (100-108). | |
Muristerone A Quick inquiry Where to buy Suppliers range | Muristerone A, a phytoecdysteroid analog of ecdysone, acts as an inducer of ecdysone-inducible gene expression systems in mammalian cells and transgenic animals. It is an agonist of the ecdysteroid receptor (Kd = 1 nM), a nuclear receptor that heterodimerizes with a retinoid X receptor ortholog and regulates arthropod development. Muristerone A stimulates Bcl-XL mRNA transcription and inhibits TRAIL- and hFasL-induced apoptosis in RKO cells. Synonyms: (2β, 3β, 5β, 11α, 22R)-2, 3, 5, 11, 14, 20, 22-Heptahydroxycholest-7-en-6-one; Mur A. Grades: ≥97% by HPLC. CAS No. 38778-30-2. Molecular formula: C27H44O8. Mole weight: 496.63. | |
Neuronal Differentiation Inducer (Isobavachin, 7-hydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)chroman-4-one) Quick inquiry Where to buy Suppliers range | A cell-permeable, 8-prenyl flavone that is shown to induce differentiation of mouse embryonic stem (ES) cells into neuronal cells and astrocytes, at 100nM. It is shown to elicit the down-regulation of p38 and JNK phosphorylation, and the up-regulation of ERK phosphorylation. Co-treatment with GGTI-298 (1000nM), a Geranyl geranyl transferase I Inhibitor selectively abolishes the IBA- but not Retinoic Acid-induced neuronal differentiation, which suggests that the differentiation inducing effect may involve protein prenylation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
PD-153035 Quick inquiry Where to buy Suppliers range | PD153035 is a ATP-competitive EGFR inhibitor with an IC50 and Ki of 25 and 6 pM. PD153035 effectively blocks the enhancement of mitogenesis, induction of early gene expression, and oncogenic transformation that occur in response to EGF receptor stimulation. With human fibroblasts and epidermoid carcinoma cells, PD153035 at nanomolar concentrations rapidly inhibits EGFR autophosphorylation. With breast and ovarian cancer cells, PD153035 not only blocks cell growth via inhibition of EGFR, but also upregulates the expression of the tumor suppressor retinoic acid receptor-beta 2 (RAR-beta2). Uses: Antineoplastic agents. Synonyms: AG 1517; AG1517; AG-1517; NSC 669364; NSC669364; NSC-669364; PD 153035; PD153035; SU 5271; SU5271; SU-5271; WHI-P 79. Grades: >98%. CAS No. 153436-54-5. Molecular formula: C16H14BrN3O2. Mole weight: 360.211. | |
Peretinoin Quick inquiry Where to buy Suppliers range | Peretinoin, also known as NIK-333, orally available, acyclic retinoid with potential antineoplastic and chemopreventive activities. Peretinoin binds to and activates nuclear retinoic acid receptors (RAR), which in turn recruit coactivator proteins and promote, with other transcriptional complexes, the transcription of target genes. As a result, this agent may modulate the expression of genes involved in the regulation of cell proliferation, cell differentiation, and apoptosis of both normal and tumor cells. Synonyms: Peretinoin; NIK-333; NIK 333; NIK333. Grades: 99.79%. CAS No. 81485-25-8. Molecular formula: C20H30O2. Mole weight: 302.458. | |
R547 Quick inquiry Where to buy Suppliers range | R547 is orally bioavailable diaminopyrimidine cyclin-dependent kinase inhibitor (CDKI) with potential antineoplastic activity. CDKI R547 selectively binds to and inhibits CDKs, especially CDK1/cyclin B, CDK2/cyclin E, and CDK4/cyclin D1. The inhibition of CDKs results in cell cycle arrest, inhibition of tumor cell proliferation, and induction of apoptosis. Through CDK inhibition, this agent also reduces phosphorylation of the retinoblastoma (Rb) protein, thus preventing activation of transcription factor E2F and so further suppressing tumor cell proliferation. CDKs are ATP-dependent serine/threonine kinases that are important regulators of cell cycle progression and are frequently overexpressed in tumor cells. Synonyms: RO-4584820; RO4584820; RO 4584820. R 547; R547; R-547. Grades: >98%. CAS No. 741713-40-6. Molecular formula: C18H21F2N5O4S. Mole weight: 441.45. | |
rac all-trans 3-(Acetyloxy) Retinol Acetate Quick inquiry Where to buy Suppliers range | rac all-trans 3-(Acetyloxy) Retinol Acetate is a metabolite of all-trans Retinoic acid. Retinoic Acid is a metabolite of Vitamin A and ajusts its functions of cellular growth and differentiation. Uses: A metabolite of all-trans retinoic acid. Synonyms: 3-(Acetyloxy)-retinol Acetate. Grades: ≥95%. CAS No. 76686-33-4. Molecular formula: C24H34O4. Mole weight: 386.52. | |
rac all-trans 3-(Acetyloxy) Retinol Acetate Quick inquiry Where to buy Suppliers range | A metabolite of all-trans Retinoic acid. Group: Biochemicals. Alternative Names: 3-(Acetyloxy)-retinol Acetate. Grades: Highly Purified. CAS No. 76686-33-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Retinamide,N-ethyl- Quick inquiry Where to buy Suppliers range | Retinamide,N-ethyl-. Group: Heterocyclic Organic Compound. Alternative Names: all-trans-N-Ethylretinamide; Ro 8-4968; Vitamin-A-saeureethylamid; Retinoic acid ethyl amide; Retinamide,N-ethyl-,all-trans; Retinamide,N-ethyl; Ethyl retinamide; Vitamin A acid ethylamide. Grades: 96%. CAS No. 33631-41-3. Molecular formula: C22H33NO. Mole weight: 327.56. IUPAC Name: (2E,4E,6E,8E)-N-ethyl-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenamide. Exact Mass: 327.25600. Boiling Point: 503ºC at 760mmHg. Flash Point: 310.3ºC. Density: 0.959g/cm3. SMILES: CCNC (=O)C=C (C)C=CC=C (C)C=CC1=C (CCCC1 (C)C)C. InChIKey: WKYDOCGICAMTKE-NBIQJRODSA-N. H-Bond Donor: 1. H-Bond Acceptor: 1. |