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An impurity of Alprazolam. Group: Biochemicals. Alternative Names: [5-Chloro-2- [3- (hydroxymethyl) -5-methyl-4H-1, 2, 4-triazol-4-yl] phenyl] phenylmethanone. Grades: Highly Purified. CAS No. 38150-27-5. Pack Sizes: 5mg. US Biological Life Sciences.
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2, 4-Difluoro-a-(1H-1,2,4-triazolyl)acetophenone
2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone (Voriconazole EP Impurity A; Voriconazole USP Related Compound C) is an antifungal activity, particularly toward Candida albicans and Candida parapsilosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 86404-63-9. Pack Sizes: 5g, 25g, 100g, 250g. Molecular Formula: C??H?F?N?O, Molecular Weight: 223.18. US Biological Life Sciences.
An intermediate in the preparation of deuterated cytidine derivatives. Group: Biochemicals. Alternative Names: 4-(1,2,4-Triazolyl)-1-(3,5-di-O-p-toluoyl-2-deoxyribosyl)-5-methyl-1H-pyrimidin-2-one-d3; 1-[2-Deoxy-3,5-bis-O-(4-methylbenzoyl)- β-D-erythro-pentofuranosyl]-4-(1H-1,2,4-triazol-1-yl)-5-methyl-2(1H)-pyrimidinone-d3. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Intermediate in the preparation of labeled 2-deoxycytidine. Group: Biochemicals. Alternative Names: 4-(1,2,4-Triazolyl)-1-(3,5-di-O-p-toluoyl-2-deoxyribosyl)-1H-pyrimidin-2-one-13C,15N2; 1-[2-Deoxy-3,5-bis-O-(4-methylbenzoyl)- β-D-erythro-pentofuranosyl]-4-(1H-1,2,4-triazol-1-yl)-2(1H)-pyrimidinone-13C,15N2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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4-(1H-1,2,4-Triazolylmethyl)benzonitrile
Heterocyclic Organic Compound. Alternative Names: 4-(1H-1, 2, 4-TRIAZOL-1-YLMETHYL)BENZONITRILE;4-(1H-1, 2, 4-TRIAZOLYLMETHYL)BENZONITRILE;4-[1-(1, 2, 4-triazolyl)-methyl-benzonitrile;4-1-(1, 2, 4-Triazolyl)-methyl-benzonitril;4-((1H-1, 2, 4-triazol-1-yl)methyl)benzonitrile (intermediate of letrozole);4-(1H-1,2,4. CAS No. 112809-25-3. Molecular formula: C10H8N4. Mole weight: 184.2. Appearance: White Solid. Purity: 0.98. Density: 1.19 g/cm³. Catalog: ACM112809253.
4-(1-Triazolylmethyl)-benzonitrile
4-(1-Triazolylmethyl)-benzonitrile. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
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4-Triazolyl-5-methyl-dU CEP
4-Triazolyl-5-methyl-dU CEP is a crucial compound utilized in the field of biomedicine. With its unique structure and properties, this chemical plays a vital role in the synthesis of pharmaceutical drugs targeting various diseases such as cancer, viral infections, and neurological disorders. Molecular formula: C42H50N7O7P. Mole weight: 795.88.
4-Triazolyl-du cep
Heterocyclic Organic Compound. Alternative Names: 4-TRIAZOLYL-DU CEP. CAS No. 109389-31-3. Molecular formula: C41H48N7O7P. Mole weight: 781.84. Catalog: ACM109389313.
4-Triazolyl-dU-CEP
4-Triazolyl-dU-CEP is a notable and significant compound, exhibiting paramount importance in the research and development of nucleoside analogs. Specifically, this compound serves as a pivotal intermediate in the progression of antiviral medications, specifically nucleotide polymerase inhibitors. Synonyms: 5'-Dimethoxytrityl-2'-deoxy-4-Triazolyl-Uridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; O4-Triazolyl-dU-CE Phosphoramidite. Grades: 95%. CAS No. 109389-31-3. Molecular formula: C41H48N7O7P. Mole weight: 781.84.
Labeled 2-Bromo-5-picoline. Used for preparation of [ [ (triazolylmethyl) pyridyl] phenyl] tetrazoles and related compounds as cardiovascular agents. Group: Biochemicals. Alternative Names: 2-Bromo-5-(methyl-d3)pyridine; 6-Bromo-3-picoline-d3; 5-(Methyl-d3)-2-bromopyridine. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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2-Chloro-4-(1-methylethoxy)-pyrimidine
2-Chloro-4-(1-methylethoxy)-pyrimidine is a reagent in the preparation of triazolyl derivatives as Syk inhibitors for therapy. Group: Biochemicals. Grades: Highly Purified. CAS No. 1250967-81-7. Pack Sizes: 1g, 10g. Molecular Formula: C7H9ClN2O, Molecular Weight: 172.61. US Biological Life Sciences.
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2-Chloro-4-(1-methylethoxy)-pyrimidine-d7
2-Chloro-4-(1-methylethoxy)-pyrimidine-d7 is the isotope labelled analog of 2-Chloro-4-(1-methylethoxy)-pyrimidine. 2-Chloro-4-(1-methylethoxy)-pyrimidine is a reagent in the preparation of triazolyl derivatives as Syk inhibitors for therapy. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C7H2D7ClN2O, Molecular Weight: 179.66. US Biological Life Sciences.
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2-Fluoro-4-hydroxybenzenemethanol
2-Fluoro-4-hydroxybenzenemethanol is a reactant used in the synthesis of cyanophenyl (triazolyl) aminomethylphenyl sulfamates as dual aromatase-sulfatase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 96740-92-0. Pack Sizes: 1g, 10g. Molecular Formula: C7H7FO2, Molecular Weight: 142.13. US Biological Life Sciences.
4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid (CAS# 641569-94-0) is used in the preparation of (pyridinyl)-N-[(triazolyl)phenyl]pyrimidinamine derivatives and (pyridinyl)-N-[oxadiazolyl)phenyl]pyrimidinamine derivatives, and can be used in the detection of their activity as antileukemia agents (neoplastic stem cell leukemia). 4-Methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid is also a Nilotinib (N465300) intermediate, which might be useful in treatment of chronic myelogenous leukemia. Synonyms: 4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzoic acid; 4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzoic acid. Grades: 98 %. CAS No. 641569-94-0. Molecular formula: C17H14N4O2. Mole weight: 306.32.
Azamulin
Highly selective human CYP3A4 inhibitor. A mutilin derivative. Group: Biochemicals. Alternative Names: 14-O- (5- (2-Amino1, 3, 4-triazolyl) thioacetyl) dihydromutilin; Antibiotic TDM 85-530; SA 85530b; (5-Amino-1H-1,2,4-triazol-3-yl)thio]acetic acid (3aS, 4R, 5S, 6R, 8R, 9R, 9aR, 10R)-6-ethyldecahydro-5-hydroxy-4, 6, 9, 10-tetramethyl-1-oxo-3a, 9-propano-3aH-cyclopentacycloocten-8-yl ester. Grades: Highly Purified. CAS No. 76530-44-4. Pack Sizes: 5mg. US Biological Life Sciences.
Copper-catalyzed coupling of imidazoles and pyrazoles with 1,1-dibromo-1-alkenes: a distinct approach for direct Nalkynylation of heteroarenes. Synthesis of benzoindoloquinolizines via a Cu(I)-mediated C-N bond formation. Efficient synthesis of 1,4-disubstituted triazolyl N-carboxamides via a simple and convenient MCR using basic alumina as a solid support. Cu(I) complexes with diethoxyphosphoryl-1,10-phenanthrolines in catalysis of C-C and C-heteroatom bond formation. Alternative Names: Bromocopper;1,10-phenanthroline;triphenylphosphane. CAS No. 25753-84-8. Molecular formula: C30H23BrCuN2P. Mole weight: 585.9. Appearance: Powder. Purity: 0.98. Canonical SMILES: C1=CC=C (C=C1)P (C2=CC=CC=C2)C3=CC=CC=C3. C1=CC2=C (C3=C (C=CC=N3)C=C2)N=C1. [Cu]Br. Catalog: ACM25753848-1.
Cefoperazone Impurity D
7-Amino-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic Acid is the 2-(triazolylthio)methyl analogue of 7-Aminocephalosporanic Acid (A603415). 7-Amino-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic Acid is used in the preparation of triazole-based semi-synthetic cephalosporins. Synonyms: (6R,7R)-7-Amino-8-oxo-3-[(1H-1,2,3-triazol-4-ylthio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; (6R-trans)-7-Amino-8-oxo-3-[(1H-1,2,3-triazol-4-ylthio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid. Grades: > 95%. CAS No. 37539-03-0. Molecular formula: C10H11N5O3S2. Mole weight: 313.36.
L760735
L760735 is a high-affinity NK1 receptor antagonist with IC50 value of 0.19 nM. It is selective over NK2 and NK3 receptors. It is used in the synthetic preparation of a (triazolylmethyl)morpholine derivative as substance P antagonist. It has anxiolytic and antidepressant-like effects and is orally active. Synonyms: L760735; L 760735; L-760735; 5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl-N,N-dimethyl-1H-1,2,3-triazole-4-methanamine Hydrochloride; [2R-[2α(R*),3α]]-5-[[2-[1-[3,5-bis(Trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-N,N-dimethyl-1H-1,2,3-triazole-4-methanamine Monohydrochloride. Grades: ≥99% by HPLC. CAS No. 188923-01-5. Molecular formula: C26H29F7N5O2Cl. Mole weight: 611.98.
Tankyrase1/2 Inhibitor III (TNKS1/2 Inhibitor III, Wnt Pathway Inhibitor XIV, 3-(4-Methoxyphenyl)-5-((4-(4-methoxyphenyl)-5-methyl-4H-1,2,4-triazol-3-ylthio)methyl)-1,2,4-oxadiazole)
A cell-permeable triazolylthiomethyl-oxadiazole compound that binds TNKS1/PARP5a and TNKS2/PARP5b with high affinity (=79 and 28nM, respectively), and acts as a potent and reversible TNKS1/2 dual inhibitor (IC50=33nM TNKS2 in an auto-PARsylation assay). Shown to interact with the adenosine diphosphate linker portion of the NAD+ donor site, and display excellent selectivity over PARP1 and PARP2 activities (IC50>19uM); stabilize Axin2 levels (EC50=709nM in SW480 cells), and antagonize Wnt signaling (IC50=215nM in HEK293-SuperTopFlash assay). Exhibits minimal activity towards cytochrome P450 enzymes (IC50=21 and 5.7uM for CYP2C9 and CYP3A4) and hERG ion channel (IC50>30uM), and adequate microsomal stability. Group: Biochemicals. Grades: Highly Purified. CAS No. 865565-29-4. Pack Sizes: 10mg. US Biological Life Sciences.
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Terconazole Impurity B
One impurity of Terbuthylazine, which could be used as a triazine herbicide. Synonyms: N4-Triazolyl Terconazole. Grades: > 95%. Molecular formula: C26H31Cl2N5O3. Mole weight: 532.47.