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UridineDiphosphate-α-D-[UL-13C6]galactose Disodium Salt
UridineDiphosphate-α-D-[UL-13C6]galactose Disodium Salt. Group: Biochemicals. Alternative Names: UDP-α-D-[UL-13C6]galactose Disodium Salt. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C913C6H22N2Na2O17P2, Molecular Weight: 616.22. US Biological Life Sciences.
Worldwide
UridineDiphosphate Choline Ammonium Salt
UridineDiphosphate Choline Ammonium Salt, a vital biochemical constituent in choline metabolism, not only serves as a precursor for acetylcholine, a neurotransmitter related to cognitive function and memory, but also exerts neuroprotective effects through a host of therapeutic pathways. Notably, studies show that this compound can enhance memory and cognitive performance in people with Alzheimer's disease and dementia while holding potential for treating neurological disorders such as Parkinson's disease and stroke. Synonyms: Uridine 5'-(Trihydrogen Diphosphate) P'-[2-(Trimethylammonio)ethyl] Ester Ammonium Salt. Grades: > 95%. Molecular formula: C14H28N4O12P2. Mole weight: 506.34.
UridineDiphosphate Choline Ammonium Salt
UridineDiphosphate Choline Ammonium Salt. Uses: For analytical and research use. Group: Carbohydrates. Catalog: APS003437. Format: Neat.
UridineDiphosphate Choline (UDPC)
UridineDiphosphate Choline (UDPC) is a fundamental biochemical compound inherent to the human body assuming indispensability in an array of intricate cellular processes. It has biomedical application for studying neurodegenerative afflictions such as Alzheimer's disease, Parkinson's disease and cognitive impairments. Notably, UDPC functions as a precursor, stimulating the production of acetylcholine. Synonyms: Uridine 5'-(Trihydrogen Diphosphate) P'-[2-(TriMethylaMMonio)ethyl] Ester Inner Salt. Grades: > 95%. CAS No. 99492-83-8. Molecular formula: C14H25N3O12P2. Mole weight: 489.32.
UridineDiphosphate Choline (UDPC)
UridineDiphosphate Choline (UDPC). Uses: For analytical and research use. Group: Impurity standards. CAS No. 99492-83-8. Molecular Formula: C14H25N3O12P2. Mole Weight: 489.31. Catalog: APB99492838.
UridineDiphosphate-GlcNaz
UridineDiphosphate-GlcNaz was tested for recognition by the GlmU uridyltransferase enzyme and for activities as substrates for glycosyltransferase. Synonyms: Uridine 5'-(trihydrogen diphosphate) P'-(2-azido-2-deoxy-α-D-glucopyranosyl) Ester Sodium Salt. CAS No. 1355005-50-3. Molecular formula: C15H21N5Na2O16P2. Mole weight: 635.28.
Uridinediphosphate glucose,[glucose-6-3h]
Heterocyclic Organic Compound. Alternative Names: URIDINEDIPHOSPHATE GLUCOSE, [GLUCOSE-6-3H]. CAS No. 108866-91-7. Molecular formula: C15H22N2O17P2T2. Mole weight: 570.32. Catalog: ACM108866917.
UridineDiphosphate Glucose (UDP-Glucose)
UridineDiphosphate Glucose is a derivative of Uridine. Uridine is a nucleoside with a uracil attached to a ribose ring. Uridine is one of the four standard components of RNA. CAS No. 133-89-1. Molecular formula: C15H24N2O17P2. Mole weight: 566.31.
2'-Deoxyuridine-5'-diphosphate
2'-Deoxyuridine-5'-diphosphate (dUDP) reigns as a paramount bioactive compound, assuming a pivotal function within the panorama of DNA research and development, wherein its utilization transpires during the advancement of antiviral therapeutic compounds. Synonyms: Deoxyuridinediphosphate; Uridine 5'-(trihydrogen diphosphate), 2'-deoxy-; 2'-deoxyuridine 5'-(trihydrogen diphosphate); ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl trihydrogen diphosphate; 2,4(1H,3H)-pyrimidinedione, 1-[2-deoxy-5-O-[hydroxy(phosphonooxy)phosphinyl]-beta-D-erythro-pentofuranosyl]-; dUDP. Grades: ≥95%. CAS No. 4208-67-7. Molecular formula: C9H14N2O11P2. Mole weight: 388.16.
2'-Deoxyuridine-5'-diphosphate trisodium salt
2'-Deoxyuridine-5'-diphosphate trisodium salt, an essential component in the DNA synthesis process, boasts multifaceted medicinal applications. Notably, it serves as an effective treatment for hyperuricemia and gout, alongside combatting viral infections such as herpes and varicella-zoster. Additionally, it's a potent reagent for DNA sequencing and labeling studies, exemplifying its versatility and necessity in the field of biological research. Synonyms: Sodium ((2R,3S,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl diphosphate; Trisodium 2'-deoxy-5'-O-[ (phosphonatooxy)phosphinato]uridine; Uridine, 2'-deoxy-, 5'-(trihydrogen diphosphate), sodium salt (1:3). Grades: ≥97% by HPLC. Molecular formula: C9H11N2Na3O11P2. Mole weight: 454.11.
Uridine 5'-diphosphate
Uridine 5'-diphosphate, a pivotal biomolecule extensively utilized in the biomedical sector, assumes the role of a substrate in myriad enzymatic reactions, especially those involving nucleic acid metabolism. Its applicability extends to RNA and DNA synthesis and alteration. Moreover, owing to its inherent ability to heighten cognitive function and neurological advancement, uridine 5'-diphosphate harbors significant potential in addressing select neurological disorders. Synonyms: Uridinediphosphate; uridine 5'-(trihydrogen pyrophosphate); 5'-uridylate diphosphate; UDP; Uridine 5'-(Trihydrogen diphosphate); 1-{5-O-[Hydroxy(phosphonooxy)phosphoryl]-β-D-ribofuranosyl}pyrimidin-2,4(1H,3H)-dione. Grades: 95%. CAS No. 58-98-0. Molecular formula: C9H14N2O12P2. Mole weight: 404.16.
Uridine-5'-diphosphate-4-deoxy-4-fluoro-α-D-galactose is the substrate of UDP-galactose 4-epimerase of Trypanosoma brucei. Synonyms: Uridine 5'-(Trihydrogen Diphosphate) P'-(4-Deoxy-4-fluoro-α-D-galactopyranosyl) Ester. CAS No. 190852-32-5. Molecular formula: C15H23FN2O16P2. Mole weight: 568.29.
Uridine-5'-diphosphate choline ammonium salt
Uridine-5'-diphosphate choline ammonium salt. Group: Biochemicals. Alternative Names: Uridine 5'-(trihydrogen diphosphate) P'-[2- (trimethylammonio) ethyl] ester inner salt. Grades: Highly Purified. CAS No. 99492-83-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C14H28N4O12P2. US Biological Life Sciences.
Worldwide
Uridine 5'-diphosphate disodium salt
UDP disodium salt is an endogenous P2Y receptor agonist which preferentially activates P2Y6. It also acts as a competitive antagonist at P2Y14 receptors. Synonyms: UDP-Na2; UDP disodium salt; Uridine 5'-diphosphoric acid disodium salt; Uridine 5'-(Trihydrogen diphosphate) Disodium Salt. Grades: ≥97% by HPLC. CAS No. 27821-45-0. Molecular formula: C9H12N2Na2O12P2. Mole weight: 448.12.
Uridine 5'-diphosphate disodium salt
Uridine 5'-diphosphate disodium salt. Group: Biochemicals. Alternative Names: UDP.2Na. Grades: Highly Purified. CAS No. 21931-53-3,27821-45-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C9H12N2O12P2Na2. US Biological Life Sciences.
Worldwide
Uridine-5'-diphosphate disodium salt
Uridine-5'-diphosphate disodium salt is a potent, selective P2Y 6 receptor native agonist ( EC 50 =300 nM; pEC 50 =6.52 for human P2Y 6 receptor). Uridine-5'-diphosphate disodium salt, an endogenous metabolite , catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 27821-45-0. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W010832.
Uridine-5'-diphosphate disodium salt 99+%
Uridine-5'-diphosphate disodium salt 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
Uridine 5'-Diphosphate Sodium Salt
A phosphorylated derivative of the nucleoside Uridine. It is further phosphorylated by nucleoside diphosphokinase to form the triphosphate analogue. Synonyms: Uridine 5'-(Trihydrogen Diphosphate) Sodium Salt; Uridine 5'-(Trihydrogen Pyrophosphate) Sodium Salt; UDP-Sodium Salt. Grades: 95%. CAS No. 21931-53-3. Molecular formula: C9H11N2Na3O12P2. Mole weight: 470.11.
Uridine-5'-diphosphate trisodium salt
Uridine-5'-diphosphate trisodium salt is an indispensable biochemical compound utilized extensively in the nucleic acid synthesis and glycogen metabolism research. Within the tapestry of scientific exploration, Uridine-5'-diphosphate trisodium salt emerges as a pivotal player, intimately intertwined with the intricate fabric of RNA metabolism assessment, viral replication elucidation and the research of afflictions such as cancer and neurological disorders. Synonyms: Uridine 5'-(trihydrogendiphosphate), trisodium salt; ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl diphosphate trisodium salt; Uridine 5'-(trisodium pyrophosphate); trisodium uridine 5'-diphosphate; Uridine, 5'-(trihydrogen diphosphate), sodium salt (1:3). Grades: ≥95%. CAS No. 19817-91-5. Molecular formula: C9H11N2Na3O12P2. Mole weight: 470.11.
Uridine 5'-(trihydrogen diphosphate) sodium salt
Uridine 5'-(trihydrogen diphosphate) sodium salt, a key player in RNA synthesis and neural plasticity modulation, has demonstrated intriguing potential as an agent for ameliorating Alzheimer's disease and related cognitive afflictions. Promisingly, this biochemical has been shown to enhance memory formation in the hippocampus - a crucial cognitive hub in the brain. Ongoing studies indicate that Uridine 5'-(trihydrogen diphosphate) sodium salt may hold the key to unlocking the mysteries of cognitive function and neurological disorders. Synonyms: Uridine 5'-(Trihydrogen Diphosphate) Sodium Salt; 1457-11-0; sodium; [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphono phosphate; Uridine5'-(TrihydrogenDiphosphate)SodiumSalt; sodium [(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl phosphono phosphate. CAS No. 1457-11-0. Molecular formula: C9H13N2NaO12P2. Mole weight: 426.14.
(1R, 4R) -4-[[ (1, 1-Dimethylethoxy) carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester is an intermediate in synthesizing trans-Abacavir Dihydrochloride (A104995), which is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridinediphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 168958-19-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C12H19NO4. US Biological Life Sciences.
(1R,4S)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol is an intermediate used in the synthesis of ent-Abacavir, which is an enantiomer of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridinediphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. CAS No. 216481-88-8. Molecular formula: C11H12ClN5O. Mole weight: 265.7.
2'-(R)-Hydroxy-2',3'dihydroabacavir is the impurity of Abacavir (A104990). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridinediphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. Molecular Formula: C14H20N6O2 2HCl, Molecular Weight: 304.357291999999. US Biological Life Sciences.
Worldwide
4-Thio-UDP
4-Thio-UDP, in the realm of compound industry, standing as a prominent biochemical compound of significant usage. Exhibiting itself as a substrate for multifarious enzymes governing intricate cellular processes, it has garnered attention due to its potential therapeutic implications concerning nucleotide metabolism and signaling pathways. Its paramountcy in research pertaining to cancer, neurodegenerative disorders and immune system impairments remains undeniable. Synonyms: 4-Thio-uridine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C9H14N2O11P2S (free acid). Mole weight: 420.22 (free acid).
5-Azido-UTP Triethylamine Salt
5-Azido-UTP Triethylamine Salt is used in the synthesis of 5-azido UDP glucose which is used as affinity probes for nucleotide diphosphate sugar binding sites. Synonyms: 5-Azido-uridine 5'-(Tetrahydrogen Triphosphate) Triethylamine Salt. Molecular formula: C9H14N5O15P3 x(C6H15N). Mole weight: 525.15.
5-Iodo-UDP
5-Iodo-UDP is an extensively utilized chemical compound assuming as a precursor for synthesizing diverse pharmaceutical intermediates and therapeutic compounds. Its substantial involvement in anti-cancer developments, coupled with its potentiality to study manifold neurological maladies, underscores its significance. Synonyms: (5I-UDP); 5-Iodo-uridine-5'-diphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C9H13N2O12P2I (free acid). Mole weight: 530.06 (free acid).
Abacavir 5'-(2,3,4-Tri-O-isobytyryl)-β-D-glucuronic Acid Methyl Ester is an intermediate used in the synthesis of various Abacavir metabolites. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridinediphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Molecular formula: C33H46N6O10. Mole weight: 686.75.
Abacavir 5'-4-Chloro-6-methylpyrimidine-2,5-diamine (Abacavir EP Impurity B) is a degradation product of Abacavir Sulfate. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridinediphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Synonyms: N6-Cyclopropyl-9-((1R,4S)-4-(((2,5-diamino-6-chloropyrimidin-4-yl)oxy)methyl)cyclopent-2-en-1-yl)-9H-purine-2,6-diamine; Abacavir USP Related Compound D; Abacavir EP Impurity B; Abacavir Impurities; Abacavir EP Impurity B. CAS No. 1443421-69-9. Molecular formula: C18H21ClN10O. Mole weight: 428.88.
α,α-trehalose-phosphate synthase (UDP-forming)
See also EC 2.4.1.36 [α,α-trehalose-phosphate synthase (GDP-forming)]. Group: Enzymes. Synonyms: UDP-glucose-glucose-phosphate glucosyltransferase; trehalosephosphate-UDP glucosyltransferase; UDP-glucose-glucose-phosphate glucosyltransferase; α,α-trehalose phosphate synthase (UDP-forming); phosphotrehalose-uridinediphosphate transglucosylase; trehalose 6-phosphate synthase; trehalose 6-phosphate synthetase; trehalose phosphate synthase; trehalose phosphate synthet. Enzyme Commission Number: EC 2.4.1.15. CAS No. 9030-7-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2376; α,α-trehalose-phosphate synthase (UDP-forming); EC 2.4.1.15; 9030-07-3; UDP-glucose-glucose-phosphate glucosyltransferase; trehalosephosphate-UDP glucosyltransferase; UDP-glucose-glucose-phosphate glucosyltransferase; α,α-trehalose phosphate synthase (UDP-forming); phosphotrehalose-uridinediphosphate transglucosylase; trehalose 6-phosphate synthase; trehalose 6-phosphate synthetase; trehalose phosphate synthase; trehalose phosphate synthetase; trehalose phosphate-uridinediphosphate glucosyltransferase; trehalose-P synthetase; transglucosylase; uridine diphosphoglucose phosphate glucosyltransferase. Cat No: EXWM-2376.
Isolated from the plants Matthiola incana (stock) and Arabidopsis thaliana (mouse-eared cress). The enzyme has similar activity with the 3-glucosides of pelargonidin, cyanidin, delphinidin, quercetin and kaempferol as well as with cyanidin 3-O-rhamnosyl-(1?6)-glucoside and cyanidin 3-O-(6-acylglucoside). There is no activity with other UDP-sugars or with cyanidin 3,5-diglucoside. Group: Enzymes. Synonyms: uridine 5'-diphosphate-xylose:anthocyanidin 3-O-glucose-xylosyltransferase; UGT79B1. Enzyme Commission Number: EC 2.4.2.51. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2681; anthocyanidin 3-O-glucoside 2'''-O-xylosyltransferase; EC 2.4.2.51; uridine 5'-diphosphate-xylose:anthocyanidin 3-O-glucose-xylosyltransferase; UGT79B1. Cat No: EXWM-2681.
Cabotegravir
Cabotegravir (GSK-1265744) is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 ( OAT1 / OAT3 ) inhibitor with IC 50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIV ADA , OAT3 and OAT1, respectively. Cabotegravir is primarily metabolized by uridinediphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir can be used to research AIDS [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK-1265744; S/GSK1265744. CAS No. 1051375-10-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15592.
Cabotegravir sodium
Cabotegravir (GSK-1265744) sodium is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 ( OAT1 / OAT3 ) inhibitor with IC 50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIV ADA , OAT3 and OAT1, respectively. Cabotegravir sodium is primarily metabolized by uridinediphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir sodium can be used to research AIDS [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GSK-1265744 sodium; S/GSK1265744 sodium. CAS No. 1051375-13-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15592A.
chitin synthase
Converts UDP-N-acetyl-α-D-glucosamine into chitin and UDP. Group: Enzymes. Synonyms: chitin-UDP N-acetylglucosaminyltransferase; chitin-uridinediphosphate acetylglucosaminyltransferase; chitin synthetase; trans-N-acetylglucosaminosylase; UDP-N-acetyl-D-glucosamine:chitin 4-β-N-acetylglucosaminyl-transferase. Enzyme Commission Number: EC 2.4.1.16. CAS No. 9030-18-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2384; chitin synthase; EC 2.4.1.16; 9030-18-6; chitin-UDP N-acetylglucosaminyltransferase; chitin-uridinediphosphate acetylglucosaminyltransferase; chitin synthetase; trans-N-acetylglucosaminosylase; UDP-N-acetyl-D-glucosamine:chitin 4-β-N-acetylglucosaminyl-transferase. Cat No: EXWM-2384.
cis-rac-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride is an intermediate of Abacavir (A105000). Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridinediphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 267668-74-6. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C11H12ClN5O HCl, Molecular Weight: 265.7. US Biological Life Sciences.
cis-rac-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol Hydrochloride is an intermediate of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridinediphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Synonyms: (1R,4S)-rel-4-(2-Amino-6-chloro-9H-purin-9-yl)2-cyclopentene-1-methanol Hydrochloride. CAS No. 267668-74-6. Molecular formula: C11H12ClN5O HCl. Mole weight: 265.7.
Cytidine 5'-diphosphate trisodium salt
Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: CDP. CAS No. 34393-59-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W008915.
Dapagliflozin-3-O-β-D-glucuronide
Dapagliflozin-3-O-β-D-glucuronide (BMS-801576) is the metabolite of Dapagliflozin (HY-10450), and is formed in the liver and kidney by uridinediphosphate glucuronosyltransferase-1A9 (UGT1A9). Dapagliflozin is a selective inhibitor for SGLT2 , that can be used to improve glycemic control and attenuate type 2 diabetes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-801576. CAS No. 1351438-75-9. Pack Sizes: 500 μg; 1 mg. Product ID: HY-125156.
Diquafosol Impurity 17
Diquafosol Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Uridine 5'-diphosphate Disodium Salt; sodium ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogendiphosphate. CAS No. 27821-45-0. Molecular Formula: C9H15N2NaO12P2. Mole Weight: 428.16. Catalog: APB27821450.
ent-Abacavir
ent-Abacavir (Abacavir EP Impurity A) is an enantiomer of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridinediphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Uses: Anti-hiv agents. Synonyms: (1R,4S)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol;(1R-cis)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (1R,4S)-Abacavir; Abacavir EP Impurity A; Abacavir Impurities; Ent-Abacavir. Grades: 97%. CAS No. 136470-79-6. Molecular formula: C14H18N6O. Mole weight: 286.33.
Involved in the biosynthesis of the linkage region of glycosaminoglycan chains as part of proteoglycan biosynthesis (chondroitin, dermatan and heparan sulfates). Requires Mn2+. Group: Enzymes. Synonyms: glucuronosyltransferase I; uridinediphosphate glucuronic acid:acceptor glucuronosyltransferase; UDP-glucuronate:3-β-D-galactosyl-4-β-D-galactosyl-O-β-D-xylosyl-protein D-glucuronosyltransferase; UDP-glucuronate:3-β-D-galactosyl-4-β-D-galactosyl-O-β-D-xylosylprotein D-glucuronosyltransferase. Enzyme Commission Number: EC 2.4.1.135. CAS No. 227184-75-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2360; galactosylgalactosylxylosylprotein 3-β-glucuronosyltransferase; EC 2.4.1.135; 227184-75-0; glucuronosyltransferase I; uridinediphosphate glucuronic acid:acceptor glucuronosyltransferase; UDP-glucuronate:3-β-D-galactosyl-4-β-D-galactosyl-O-β-D-xylosyl-protein D-glucuronosyltransferase; UDP-glucuronate:3-β-D-galactosyl-4-β-D-galactosyl-O-β-D-xylosylprotein D-glucuronosyltransferase. Cat No: EXWM-2360.
ganglioside galactosyltransferase
The substrate is also known as gangloside GM2, the product as gangloside GM1a. Group: Enzymes. Synonyms: UDP-galactose-ceramide galactosyltransferase; uridine diphosphogalactose-ceramide galactosyltransferase; UDP galactose-LAC Tet-ceramide α-galactosyltransferase;. Enzyme Commission Number: EC 2.4.1.62. CAS No. 37217-28-0. Galactosyltransferase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2605; ganglioside galactosyltransferase; EC 2.4.1.62; 37217-28-0; UDP-galactose-ceramide galactosyltransferase; uridine diphosphogalactose-ceramide galactosyltransferase; UDP galactose-LAC Tet-ceramide α-galactosyltransferase; UDP-galactose-GM2 galactosyltransferase; uridine diphosphogalactose-GM2 galactosyltransferase; uridinediphosphate D-galactose:glycolipid galactosyltransferase; UDP-galactose:N-acetylgalactosaminyl-(N-acetylneuraminyl) galactosyl-glucosyl-ceramide galactosyltransferase; UDP-galactose-GM2 ganglioside galactosyltransferase; GM1-synthase; UDP-galactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine β-1,3-D-galactosyltransferase; UDP-galactose:N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-(1?4)-β-D-glucosyl-N-acylsphingosine 3-β-D-galactosyltransferase. Cat No: EXWM-2605.
glucosylceramide β-1,4-galactosyltransferase
Involved in the synthesis of several different major classes of glycosphingolipids. Group: Enzymes. Synonyms: lactosylceramide synthase; uridinediphosphate-galactose:glucosyl ceramide β 1-4 galactosyltransferase; UDP-Gal:glucosylceramide β1?4galactosyltransferase; GalT-2 (misleading); UDP-galactose:β-D-glucosyl-(1<->1)-ceramide β-1,4-galactosyltransferase. Enzyme Commission Number: EC 2.4.1.274. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2506; glucosylceramide β-1,4-galactosyltransferase; EC 2.4.1.274; lactosylceramide synthase; uridinediphosphate-galactose:glucosyl ceramide β 1-4 galactosyltransferase; UDP-Gal:glucosylceramide β1?4galactosyltransferase; GalT-2 (misleading); UDP-galactose:β-D-glucosyl-(1<->1)-ceramide β-1,4-galactosyltransferase. Cat No: EXWM-2506.
linamarin synthase
The enzyme glucosylates the cyanohydrins of butanone and pentan-3-one as well as that of acetone. Group: Enzymes. Synonyms: uridine diphosphoglucose-ketone glucosyltransferase; uridinediphosphate-glucose-ketone cyanohydrin β-glucosyltransferase; UDP glucose ketone cyanohydrin glucosyltransferase; UDP-glucose:ketone cyanohydrin β-glucosyltransferase; uridine diphosphoglucose-ketone cyanohydrin glucosyltransferase. Enzyme Commission Number: EC 2.4.1.63. CAS No. 37277-68-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2606; linamarin synthase; EC 2.4.1.63; 37277-68-2; uridine diphosphoglucose-ketone glucosyltransferase; uridinediphosphate-glucose-ketone cyanohydrin β-glucosyltransferase; UDP glucose ketone cyanohydrin glucosyltransferase; UDP-glucose:ketone cyanohydrin β-glucosyltransferase; uridine diphosphoglucose-ketone cyanohydrin glucosyltransferase. Cat No: EXWM-2606.
lipopolysaccharide 3-α-galactosyltransferase
Transfers α-D-galactosyl residues to D-glucose in the partially completed core of lipopolysaccharide [cf. EC 2.4.1.56 (lipopolysaccharide N-acetylglucosaminyltransferase), EC 2.4.1.58 (lipopolysaccharide glucosyltransferase I) and EC 2.4.1.73 (lipopolysaccharide glucosyltransferase II)]. Group: Enzymes. Synonyms: UDP-galactose:lipopolysaccharide α,3-galactosyltransferase; UDP-galactose:polysaccharide galactosyltransferase; uridinediphosphate galactose:lipopolysaccharide α-3-galactosyltransferase; uridine diphosphogalactose-lipopolysaccharide α,3-galactosyltransferase; UDP-galactose:lipopolysaccharide 3-α-D-galactosyltransferase. Enzyme Commission Number: EC 2.4.1.44. CAS No. 9073-98-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2590; lipopolysaccharide 3-α-galactosyltransferase; EC 2.4.1.44; 9073-98-7; UDP-galactose:lipopolysaccharide α,3-galactosyltransferase; UDP-galactose:polysaccharide galactosyltransferase; uridinediphosphate galactose:lipopolysaccharide α-3-galactosyltransferase; uridine diphosphogalactose-lipopolysaccharide α,3-galactosyltransferase; UDP-galactose:lipopolysaccharide 3-α-D-galactosyltransferase. Cat No: EXWM-2590.
lipopolysaccharide glucosyltransferase I
Transfers glucosyl residues to the backbone portion of lipopolysaccharide [cf. EC 2.4.1.44 (lipopolysaccharide 3-α-galactosyltransferase, EC 2.4.1.56 (lipopolysaccharide N-acetylglucosaminyltransferase) and EC 2.4.1.73 (lipopolysaccharide glucosyltransferase II)]. Group: Enzymes. Synonyms: UDP-glucose:lipopolysaccharide glucosyltransferase I; lipopolysaccharide glucosyltransferase; uridinediphosphate glucose:lipopolysaccharide glucosyltransferase I; uridine diphosphoglucose-lipopolysaccharide glucosyltransferase. Enzyme Commission Number: EC 2.4.1.58. CAS No. 9074-00-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2603; lipopolysaccharide glucosyltransferase I; EC 2.4.1.58; 9074-00-4; UDP-glucose:lipopolysaccharide glucosyltransferase I; lipopolysaccharide glucosyltransferase; uridinediphosphate glucose:lipopolysaccharide glucosyltransferase I; uridine diphosphoglucose-lipopolysaccharide glucosyltransferase. Cat No: EXWM-2603.
MRS 2693 trisodium salt
MRS 2693 trisodium salt is a selective P2Y6 agonist (EC50 = 0.015 μM at the hP2Y6 receptor), with no activity at other P2Y subtypes. Synonyms: Uridine 5'-(trihydrogen diphosphate), 5-iodo-, sodium salt (1:3); MRS 2693; 5-Iodo-UDP Trisodium Salt; 5-Iodouridine 5'-(trihydrogen diphosphate) sodium salt; 5-Iodouridine-5'-O-diphosphate trisodium salt; MRS2693; MRS-2693. Grades: ≥95% by HPLC. CAS No. 1448858-83-0. Molecular formula: C9H10IN2Na3O12P2. Mole weight: 596.00.
N3-Phenacyl-UDP
N3-Phenacyl-UDP, a groundbreaking biomedical innovation, revolutionizes targeted drug delivery in the realm of combating select cancers and infections. By adroitly harnessing the distinctive attributes encoded within N3-Phenacyl-UDP, this extraordinary concoction empowers meticulous transport of curative agents to designated cellular microenvironments or tissues, thereby amplifying therapeutic prowess while simultaneously mitigating collateral detriments. Synonyms: N; -Phenacyl-uridine-5'-diphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 917567-60-3. Molecular formula: C17H20N2O13P2(free acid). Mole weight: 522.29 (free acid).
Native Baker's yeast (S. cerevisiae) Nucleoside 5'-Diphosphate Kinase
Nucleoside 5'-diphosphate kinase is a cytosolic enzyme. Nucleoside 5'-diphosphate kinase from Saccharomyces cerevisiae is found highly expressed in the cytoplasm. It affects DNA synthesis, in part, by binding to Cdc8p. Nucleoside 5?-diphosphate kinase is a cytosolic enzyme. Applications: Nucleoside 5?-diphosphate kinase has been used in a study to examine a possible intracellular activity of the drug disodium cromoglycate in mast cells. it has also been used in a study to investigate protein synthesis in rabbit reticul ocytes. Group: Enzymes. Synonyms: nucleoside 5'-diphosphate kinase; nucleoside diphosphate (UDP) kinase; nucleoside diphosphokinase; nucleotide phosphate kinase; UDP kinase; uridinediphosphate kinase; nucleoside-diphosphate kinase; EC 2.7.4.6; 9026-51-1; NDPK. Enzyme Commission Number: EC 2.7.4.6. CAS No. 9026-51-1. NDPK. Storage: -20°C. Form: lyophilized powder; essentially sulfate-free powder. Contains sodium Citrate with a trace of magnesium and EDTA salts. Source: Baker's yeast (S. cerevisiae). nucleoside 5'-diphosphate kinase; nucleoside diphosphate (UDP) kinase; nucleoside diphosphokinase; nucleotide phosphate kinase; UDP kinase; uridinediphosphate kinase; nucleoside-diphosphate kinase; EC 2.7.4.6; 9026-51-1; NDPK. Cat No: NATE-0476.
UTP-glucose-1-phosphate uridylyltransferase is an enzyme associated with glycogenesis. It synthesizes UDP-glucose from glucose-1-phosphate and UTP; i.e., glucose-1-phosphate + UTP<-> UDP-glucose + pyrophosphate. Applications: Uridine-5?-diphosphoglucose pyrophosphorylase has been used in assays to determine the concentration of pyrophosphate in human urine samples. Group: Enzymes. Synonyms: UDP glucose pyrophosphorylase; glucose-1-phosphate uridylyltransferase; UDPG phosphorylase; UDPG pyrophosphorylase; uridine 5'-diphosphoglucose pyrophosphorylase; uridine diphosphoglucose pyrophosphorylase; uridinediphosphate-D-glucose pyrophosphorylase; uridine-diphosphate glucose pyrophosphorylase; EC 2.7.7.9; 9026-22-6. Enzyme Commission Number: EC 2.7.7.9. CAS No. 9026-22-6. UDPG pyrophosphorylase. Activity: > 50 units/mg protein. Storage: -20°C. Form: Lyophilized, sulfate-free powder containing Citrate buffer salt. Source: Baker's yeast. UDP glucose pyrophosphorylase; glucose-1-phosphate uridylyltransferase; UDPG phosphorylase; UDPG pyrophosphorylase; uridine 5'-diphosphoglucose pyrophosphorylase; uridine diphosphoglucose pyrophosphorylase; uridinediphosphate-D-glucose pyrophosphorylase; uridine-diphosphate glucose pyrophosphorylase; EC 2.7.7.9; 9026-22-6. Cat No: NATE-0728.
Native Bovine Nucleoside 5'-Diphosphate Kinase
Nucleoside-diphosphate kinases are enzymes that catalyze the exchange of phosphate groups between different nucleoside diphosphates. NDK activities maintain an equilibrium between the concentrations of different nucleoside triphosphates such as, for example, when GTP produced in the citric acid (Krebs) cycle is converted to ATP. Nucleoside Diphosphate Kinase exists in two isoforms in eukaryotic cells, NDK-A and NDK-B. These enzymes are found expressed both in the mitochondria and the cytoplasm. Nucleoside diphosphate kinase exists in two isoforms in eukaryotic cells, ndk-a and ndk-b. these enzymes are found expressed both in the mit ochondria and the cytoplasm. Applica...cleotide phosphate kinase; UDP kinase; uridinediphosphate kinase; ATP:nucleoside diphosphate phosphotransferase; NDPK; NDKs; NDP Kinase; EC 2.7.4.6; 9026-51-1. Enzyme Commission Number: EC 2.7.4.6. CAS No. 9026-51-1. NDPK. Activity: > 1,000 units/mg protein (biuret). Storage: 2-8°C. Form: buffered aqueous glycerol solution. Source: Bovine liver. Species: Bovine. nucleoside-diphosphate kinase; nucleoside 5'-diphosphate kinase; nucleoside diphosphate (UDP) kinase; nucleoside diphosphokinase; nucleotide phosphate kinase; UDP kinase; uridinediphosphate kinase; ATP:nucleoside diphosphate phosphotransferase; NDPK; NDKs; NDP Kinase; EC 2.7.4.6; 9026-51-1. Cat No: NATE-0477.
The enzyme UDP-glucose 4-epimerase (EC 5.1.3.2), also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells. This enzyme performs the final step in the Leloir pathway of galactose metabolism, catalyzing the reversible conversion of UDP-galactose to UDP-glucose. GALE tightly binds nicotinamide adenine dinucleotide (NAD+), a co-factor required for catalytic activity. Group: Enzymes. Synonyms: UDP-galactose 4-epimerase; uridine diphosphoglucose epimerase; galactowaldenase; UDPG-4-epimerase; uridinediphosphate galactose 4-epimerase; uridine diphospho-gal. Enzyme Commission Number: EC 5.1.3.2. CAS No. 9032-89-7. UDP-Glc 4-epimerase. Activity: 10-20 units/mg protein (modified Warburg-Christian). Storage: -20°C. Form: Lyophilized powder containing approx. 40% buffer salts. Source: Galactose-adapted yeast. UDP-galactose 4-epimerase; uridine diphosphoglucose epimerase; galactowaldenase; UDPG-4-epimerase; uridinediphosphate galactose 4-epimerase; uridine diphospho-galactose-4-epimerase; UDP-glucose epimerase; UDP-galactose 4-epimerase; 4-epimerase; UDPG-4-epimerase; uridine diphosphoglucose 4-epimerase; uridinediphosphate glucose 4-epimerase; UDP-D-galactose 4-epimerase; EC 5.1.3.2; UDP-glucose 4-epimerase; GALE. Pack: vial. Cat No: NATE-0275.
N-hydroxythioamide S-β-glucosyltransferase
Involved with EC 2.8.2.24, desulfoglucosinolate sulfotransferase, in the biosynthesis of thioglucosides in cruciferous plants. Group: Enzymes. Synonyms: desulfoglucosinolate-uridinediphosphate glucosyltransferase; uridine diphosphoglucose-thiohydroximate glucosyltransferase; thiohydroximate β -D-glucosyltransferase; UDPG:thiohydroximate glucosyltransferase; thiohydroximate S-glucosyltransferase; thiohydroximate glucosyltransferase; UDP-glucose:thiohydroximate S-β-D-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.195. CAS No. 9068-14-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2422; N-hydroxythioamide S-β-glucosyltransferase; EC 2.4.1.195; 9068-14-8; desulfoglucosinolate-uridinediphosphate glucosyltransferase; uridine diphosphoglucose-thiohydroximate glucosyltransferase; thiohydroximate β -D-glucosyltransferase; UDPG:thiohydroximate glucosyltransferase; thiohydroximate S-glucosyltransferase; thiohydroximate glucosyltransferase; UDP-glucose:thiohydroximate S-β-D-glucosyltransferase. Cat No: EXWM-2422.
nucleoside-diphosphate kinase
Many nucleoside diphosphates can act as acceptors, while many ribo- and deoxyribonucleoside triphosphates can act as donors. Group: Enzymes. Synonyms: nucleoside 5'-diphosphate kinase; nucleoside diphosphate (UDP) kinase; nucleoside diphosphokinase; nucleotide phosphate kinase; UDP kinase; uridinediphosphate kinase. Enzyme Commission Number: EC 2.7.4.6. CAS No. 9026-51-1. NDPK. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3216; nucleoside-diphosphate kinase; EC 2.7.4.6; 9026-51-1; nucleoside 5'-diphosphate kinase; nucleoside diphosphate (UDP) kinase; nucleoside diphosphokinase; nucleotide phosphate kinase; UDP kinase; uridinediphosphate kinase. Cat No: EXWM-3216.
Nucleoside-Diphosphate Kinase (Crude Enzyme)
Nucleoside-diphosphate kinases (NDPKs, also NDP Kinase, (poly)nucleotide kinases and nucleoside diphosphokinases) are enzymesthat catalyze the exchange of terminal phosphate between different nucleoside diphosphates (NDP) and triphosphates (NTP) in a reversible manner to produce nucleotide triphosphates. Many NDP serve as acceptor while NTP are donors of phosphate group. The general reaction via ping-pong mechanism is as follows: XDP + YTP ?? XTP + YDP (X and Y each represent different nitrogenous base). NDPK activities maintain an equilibrium between the concentrations of different nucleoside triphosphates such as, for example, when guanosine triphosphate (GTP) produce... activity was briefly purified from engineered E. coli. Applications: Medicine. Group: Enzymes. Synonyms: nucleoside 5'-diphosphate kinase; nucleoside diphosphate (UDP) kinase; nucleoside diphosphokinase; nucleotide phosphate kinase; UDP kinase; uridinediphosphate kinase. Enzyme Commission Number: EC 2.7.4.6. CAS No. 9026-51-1. NDPK. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. nucleoside 5'-diphosphate kinase; nucleoside diphosphate (UDP) kinase; nucleoside diphosphokinase; nucleotide phosphate kinase; UDP kinase; uridinediphosphate kinase. Pack: 100ml. Cat No: NATE-1829.
nucleoside diphosphate phosphatase
The enzyme, which appears to be limited to metazoa, acts on multiple nucleoside diphosphates as well as on D-ribose 5-diphosphate. Specificity depends on species and isoform. Group: Enzymes. Synonyms: nucleoside-diphosphatase; thiaminpyrophosphatase; UDPase; inosine diphosphatase; adenosine diphosphatase; IDPase; ADPase; adenosinepyrophosphatase; guanosine diphosphatase; guanosine 5'-diphosphatase; inosine 5'-diphosphatase; uridine diphosphatase; uridine 5'-diphosphatase; type B nucleoside diphosphatase; GDPase; CDPase; nucleoside 5'-diphosphatase; type L nucleoside diphosphatase; NDPase; nucleoside diphosphate phosphohydrolase. Enzyme Commission Number: EC 3.6.1.6. CAS No. 9027-69-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4632; nucleoside diphosphate phosphatase; EC 3.6.1.6; 9027-69-4; nucleoside-diphosphatase; thiaminpyrophosphatase; UDPase; inosine diphosphatase; adenosine diphosphatase; IDPase; ADPase; adenosinepyrophosphatase; guanosine diphosphatase; guanosine 5'-diphosphatase; inosine 5'-diphosphatase; uridine diphosphatase; uridine 5'-diphosphatase; type B nucleoside diphosphatase; GDPase; CDPase; nucleoside 5'-diphosphatase; type L nucleoside diphosphatase; NDPase; nucleoside diphosphate phosphohydrolase. Cat No: EXWM-4632.
rac-Abacavir Sulfate
rac-Abacavir Sulfate is a racemic mixture of ent-Abacavir and Abacavir Sulfate. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridinediphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Synonyms: Abacavir Sulfate Racemic; (4-[2-Amino-6-(cyclopropylamino)-9H-purin-9yl]-2-cyclopentene-1-methanol Sulfate (2:1). Molecular formula: C28H38N12O6S. Mole weight: 670.47.
Raltegravir Potassium Salt
Raltegravir is a potent, selective, and orally bioavailable inhibitor of HIV integrase (IC50 = 15 nM). It is metabolized primarily by uridinediphosphate glucuronosyltransferase 1A. Raltegravir has long-term efficacy and safety in managing HIV-1 infection in adults, children, and adolescents. Uses: Anti-hiv agents. Synonyms: MK-0518; MK 0518; MK0518; Raltegravir. Grades: 98%. CAS No. 871038-72-1. Molecular formula: C20H20FKN6O5. Mole weight: 482.514.
RX-3117
RX-3117, also known as TV-1360 and fluorocyclopentenylcytosine, is an orally available and potent DNA synthesis inhibitor with potential antineoplastic activity. Upon administration, the cytidine analogue RX-3117 is taken up by cells through a carrier-mediated transporter, phosphorylated by uridine cytidine kinase (UCK) and then further phosphorylated to its diphosphate (RX-DP) and triphosphate forms (RX-TP). The triphosphate form is incorporated into RNA and inhibits RNA synthesis. The diphosphate RX-DP is reduced by ribonucleotide reductase (RR) to dRX-DP; its triphosphate form (dRX-TP) is incorporated into DNA. In addition, RX-3117 also inhibits DNA methyltransferase 1 (DNMT1). This eventually leads to cell cycle arrest and the induction of apoptosis. UCK is the rate-limiting enzyme in the pyrimidine-nucleotide salvage pathway. Synonyms: RX3117; RX 3117; TV-1360; TV1360; TV 1360; fluorocyclopentenylcytosine. Grades: >98%. CAS No. 865838-26-2. Molecular formula: C10H12FN3O4. Mole weight: 257.221.
sphingosine β-galactosyltransferase
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. Group: Enzymes. Synonyms: psychosine-UDP galactosyltransferase; galactosyl-sphingosine transferase; psychosine-uridinediphosphate galactosyltransferase; UDP-galactose:sphingosine O-galactosyl transferase; uridine diphosphogalactose-sphingosine β-galactosyltransferase; UDP-galactose:sphingosine 1-β-galactotransferase; UDP-galactose:sphingosine 1-β-galactosyltransferase. Enzyme Commission Number: EC 2.4.1.23. CAS No. 9032-90-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2459; sphingosine β-galactosyltransferase; EC 2.4.1.23; 9032-90-0; psychosine-UDP galactosyltransferase; galactosyl-sphingosine transferase; psychosine-uridinediphosphate galactosyltransferase; UDP-galactose:sphingosine O-galactosyl transferase; uridine diphosphogalactose-sphingosine β-galactosyltransferase; UDP-galactose:sphingosine 1-β-galactotransferase; UDP-galactose:sphingosine 1-β-galactosyltransferase. Cat No: EXWM-2459.
sucrose-phosphate synthase
Requires Mg2+ or Mn2+ for maximal activity. The enzyme from Synechocystis sp. strain PCC 6803 is not specific for UDP-glucose as it can use ADP-glucose and, to a lesser extent, GDP-glucose as substrates. The enzyme from rice leaves is activated by glucose 6-phosphate but that from cyanobacterial species is not. While the reaction catalysed by this enzyme is reversible, the enzyme usually works in concert with EC 3.1.3.24, sucrose-phosphate phosphatase, to form sucrose, making the above reaction essentially irreversible. The F in sucrose 6F-phosphate is used to indicate that the fructose residue of sucrose carries the substituent. Group: Enzymes. Synonyms: UDP-glucose-fructose-phosphate glucosyltransferase; sucrosephosphate-UDP gluco. Enzyme Commission Number: EC 2.4.1.14. CAS No. 9030-6-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2365; sucrose-phosphate synthase; EC 2.4.1.14; 9030-06-2; UDP-glucose-fructose-phosphate glucosyltransferase; sucrosephosphate-UDP glucosyltransferase; UDP-glucose-fructose-phosphate glucosyltransferase; SPS; uridine diphosphoglucose-fructose phosphate glucosyltransferase; sucrose 6-phosphate synthase; sucrose phosphate synthetase; sucrose phosphate-uridinediphosphate glucosyltransferase; sucrose phosphate synthase. Cat No: EXWM-2365.
sucrose synthase
Although UDP is generally considered to be the preferred nucleoside diphosphate for sucrose synthase, numerous studies have shown that ADP serves as an effective acceptor molecule to produce ADP-glucose. Sucrose synthase has a dual role in producing both UDP-glucose (necessary for cell wall and glycoprotein biosynthesis) and ADP-glucose (necessary for starch biosynthesis). Group: Enzymes. Synonyms: UDPglucose-fructose glucosyltransferase; sucrose synthetase; sucrose-UDP glucosyltransferase; sucrose-uridinediphosphate glucosyltransferase; uridine diphosphoglucose-fructose glucosyltransferase. Enzyme Commission Number: EC 2.4.1.13. CAS No. 9030-5-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2355; sucrose synthase; EC 2.4.1.13; 9030-05-1; UDPglucose-fructose glucosyltransferase; sucrose synthetase; sucrose-UDP glucosyltransferase; sucrose-uridinediphosphate glucosyltransferase; uridine diphosphoglucose-fructose glucosyltransferase. Cat No: EXWM-2355.
trans-Abacavir Dihydrochloride
trans-Abacavir Dihydrochloride is an impurity of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridinediphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. Synonyms: (1R,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol Diydrochloride. Grades: 98%. Molecular formula: C14H20Cl2N6O. Mole weight: 359.25.
UDP-2-Acetamido-2,4-dideoxy-4-fluorogalactose
UDP-2-Acetamido-2,4-dideoxy-4-fluorogalactose is an indispensable compound assuming a pivotal status in the intricate domain of glycoconjugate synthesis. By serving as a formidable substrate for a plethora of enzymes actively participating in glycosylation processes, this remarkable compound effectively facilitates the intricate modification of proteins and lipids. Synonyms: Uridine 5'-(2-acetamido-2,4-dideoxy-4-fluoro-a-D-galactopyranosyl)diphosphate; dilithium,[(2R,3R,4R,5R,6R)-3-acetamido-5-fluoro-4-hydroxy-6-(hydroxymethyl)oxan-2-yl][[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] phosphate; Uridine 5'-(trihydrogen diphosphate),P'-(2-(acetylamino)-2,4-dideoxy-4-fluoro-alpha-D-galactopyranosyl) ester, dilithium salt; Udp-adfg. CAS No. 120596-20-5. Molecular formula: C17H24FLi2N3O16P2. Mole weight: 621.21.
UDP-2-deoxy-2-fluoro-D-galactose
UDP-2-deoxy-2-fluoro-D-galactose is a valuable tool in the biomedical industry known for its ability to mimic natural carbohydrates. It can be utilized to investigate the potential therapeutic applications and drug design targeting specific diseases related to carbohydrate metabolism. Synonyms: UDP-2FGal; Uridine 5-(trihydrogen diphosphate), P-(2-deoxy-2-fluoro-α-D-galactopyranosyl) ester. CAS No. 118694-15-8. Molecular formula: C15H23FN2O16P2. Mole weight: 568.29.
UDP-2-deoxy-2-fluoro-D-glucose
UDP-2-deoxy-2-fluoro-D-glucose is an indispensable compound, serving as a potent tool in positron emission tomography (PET) imaging. By virtue of its radiochemical attributes, this glucose analog enables the non-intrusive observation of in vivo glucose metabolism. Its application extends to the research of multifarious conditions encompassing cancer, neurodegenerative ailments and infectious pathologies. Synonyms: Uridine-2-deoxy-2-fluoro-D-glucose diphosphate ester. CAS No. 67341-43-9. Molecular formula: C15H23FN2O16P2. Mole weight: 568.29.
UDP-2-deoxy-2-fluoro-D-mannose
UDP-2-deoxy-2-fluoro-D-mannose is an antiviral compound in the dynamic biomedical sector used for studying diverse viral infections, notably influenza. Synonyms: Uridine 5-(trihydrogen diphosphate), P-(2-deoxy-2-fluoro-a-D-mannopyranosyl) ester. CAS No. 67341-44-0. Molecular formula: C15H23FN2O16P2. Mole weight: 568.29.
UDP-2-deoxy-2-iodo-D-glucose
UDP-2-deoxy-2-iodo-D-glucose stands as an indispensable compound mainly used for examining the intricate syntheses of glycoproteins and traversing the labyrinth of cellular pathways. By virtue of its distinctive iodine-based modification, UDP-2-deoxy-2-iodo-D-glucose assumes an irreplaceable role in unraveling the enigmatic facets of carbohydrate-driven ailments, prominently including cancer and metabolic disorders. Synonyms: Uridine 5'-(trihydrogen diphosphate),P'-(2-deoxy-2-iodo-a-D-glucopyranosyl)ester. Molecular formula: C15H23N2O16P2I. Mole weight: 676.20.
UDP-2-deoxy-a-D-galactose ammonium salt
UDP-2-deoxy-a-D-galactose ammonium salt, a biochemical product of paramount significance in the biomedical industry, serves predominantly as a substrate in enzymatic reactions, in particular, the biosynthesis of glycoconjugates. This product constitutes an indispensable component of studies pertaining to diseases related to defects in glycosylation, such as congenital disorders of glycosylation and cancer. Furthermore, the compound, with its intrinsic therapeutic value, facilitates the development of potential drugs for the treatment of said diseases. Synonyms: Uridine-5'-diphosphate-2-deoxy-a-D-galactose ammonium salt. Molecular formula: C15H30N4O16P2. Mole weight: 584.36.
UDP-(3-O-(R-3-hydroxydecanoyl)) N-acetylglucosamine is an indispensable compound, assuming a critical function in the synthetic pathway of lipid A, a fundamental constituent of bacterial lipopolysaccharides. Its application within the realm of microbial pathogenesis research is extensive, particularly in elucidating the intricate mechanisms underlying lipopolysaccharide biosynthesis and in identifying prospective drug targets to confront pernicious bacterial infections. Synonyms: Uridine-5'-Diphosphate-3-O-(R-3-Hydroxydecanoyl)-N-Acetyl-D-Glucosamine; (3R)- (2R, 3R, 4R, 5S, 6R)-3-Acetamido-2- ( ( ( ( ( ( (2R, 3S, 4R, 5R)-5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)-3, 4-dihydroxytetrahydrofuran-2-yl)methoxy) (hydroxy)phosphoryl)oxy) (hydroxy)phosphoryl)oxy)-5-hydroxy-6- (hydroxymethyl)tetrahydro-2H-pyran-4-yl 3-hydroxydecanoate; [(2R,3R,4R,5S,6R)-3-acetamido-2-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl] (3R)-3-hydroxydecanoate; 953426-26-1; U21; Q27466807; (2R, 3R, 4R, 5S, 6R)-3- (acetylamino)-2-{[ (R)-{[ (S)-{[ (2R, 3S, 4R, 5R)-5- (2, 4-dioxo-3, 4-dihydropyrimidin-1 (2H)-yl)-3, 4-dihydroxytetrahydrofuran-2-yl]methoxy} (hydroxy)phosphoryl]oxy} (hydroxy)phosphoryl]oxy}-5-hydroxy-6- (hydroxymethyl)tetrahydro-2H-pyran-4-yl (3R)-3-hydroxydecanoate (non-preferred name). CAS No. 953426-26-1. Molecular formula: C27H45N3O19P2. Mole weight: 777.60.
UDP-3-O[R-3-Hydroxymyristoyl]-N-acetylglucosamine
A lipid A precursor for Escherichia coli. Synonyms: UDP-3-O[R-3-Hydroxymyristoyl]-GlcNAc; P'-[2-(acetylamino)?-2-deoxy-3-O-[(3R)?-3-hydroxy-1-oxotetradecyl]?-α-D-glucopyranosyl] Ester Uridine 5'-(trihydrogen diphosphate)?. CAS No. 108636-29-9. Molecular formula: C31H53N3O19P2. Mole weight: 833.71.
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