American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

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Product
Tixagevimab Tixagevimab (AZD8895) is a human monoclonal antibody that targets the SARS-CoV-2 receptor binding domain (RBD). It exhibits neutralizing activity against SARS-CoV-2 by binding to the RBD and the S-glycoprotein ectodomain and blocking S-glycoprotein-mediated binding to the receptor [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AZD8895. CAS No. 2420564-02-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99556. MedChemExpress MCE
Tixosil Tixosil. Group: Polymers. Alfa Chemistry Materials 3
Tizanidine Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. Uses: Scientific research. Group: Signaling pathways. CAS No. 51322-75-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0194. MedChemExpress MCE
Tizanidine-d4 Tizanidine-d 4 is the deuterium labeled Tizanidine. Tizanidine is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1188331-19-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0194S. MedChemExpress MCE
Tizanidine-d4 Labeled Tizanidine, a muscle relaxant. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
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Tizanidine-[d4] Tizanidine-[d4] is the labelled analogue of Tizanidine. Tizanidine is an α2 adrenergic agonist used as a muscle relaxant. Synonyms: Tizanidine D4; 5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl-d4)-2,1,3-benzothiadiazol-4-amine. Grade: 100% HPLC; 99% atom D. CAS No. 1188331-19-2. Molecular formula: C9H4DClN5S. Mole weight: 257.74. BOC Sciences 2
Tizanidine-[d4] Hydrochloride Tizanidine-[d4] Hydrochloride is the labelled analogue of Tizanidine, which has been found to be an α2-adrenergic agonist and could be used as a muscle as well as skeletal relaxant. Synonyms: Tizanidine-d4 Hydrochloride; 5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl-d4)-2,1,3-benzothiadiazol-4-amine Hydrochloride. Grade: 95% by HPLC; 95% atom D. CAS No. 1188263-51-5. Molecular formula: C9H5D4Cl2N5S. Mole weight: 294.20. BOC Sciences 2
Tizanidine hydrochloride Tizanidine hydrochloride is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. Uses: Scientific research. Group: Signaling pathways. CAS No. 64461-82-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0194A. MedChemExpress MCE
Tizanidine hydrochloride Tizanidine hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 64461-82-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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Tizanidine hydrochloride 5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C9H8N5ClS €¢HCl. CAS No. 64461-82-1. Prepack ID 71395830-5g. Molecular Weight 290.17. See USA prepack pricing. Molekula Americas
Tizanidine, Hydrochloride An α2-adrenergic agonist; centrally active myotonolytic. A muscle relaxant (skeletal). Group: Biochemicals. Grades: Highly Purified. CAS No. 64461-82-1. Pack Sizes: 10mg, 50mg, 100mg, 250mg. Molecular Formula: C?H?Cl?N?S. US Biological Life Sciences. USBiological 1
Worldwide
Tizanidine Related Compound A United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products 2
Tizanidine Related Compound B United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products 2
Tizanidine Related Compound C United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. Alfa Chemistry Analytical Products 2
Tizoxanide A metabolite of Nitazoxonide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 1
Worldwide
Tizoxanide Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC50 of 0.46μM and 0.15 μM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-κB and the MAPK signaling pathways in LPS-treated macrophage cells. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 173903-47-4. Molecular formula: C10H7N3O4S. Mole weight: 265.243. Purity: 0.97. Canonical SMILES: O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=CC=C2O. Product ID: ACM173903474. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Tizoxanide Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC 50 of 0.46μM and 0.15 μM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-κB and the MAPK signaling pathways in LPS-treated macrophage cells [1] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TIZ. CAS No. 173903-47-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12687. MedChemExpress MCE
Tizoxanide-[d4] Tizoxanide-[d4] is the labelled analogue of Tizoxanide. Tizoxanide is the active metabolite of nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia or Crytosporidium parvum. Tizoxanide is active against anaerobic bacteria, protozoan parasites, and viruses. Synonyms: Tizoxanide D4; 2-Hydroxy-N-(5-nitro-2-thiazolyl)benzamide-d4. Grade: 95% by HPLC; 98% atom D. CAS No. 1246817-56-0. Molecular formula: C10H3D4N3O4S. Mole weight: 269.27. BOC Sciences 2
TiZrVTa High-Entropy Alloy Unlike most current alloy materials, high-entropy alloys are alloy materials that contain equimolar or approximately equimolar elements. TiZrVTa High-Entropy Alloy is composed of Ti, Zr, V, and Ta. Uses: Military use, replace part of superalloy. Group: High entropy alloys. Pack Sizes: Our TiZrVTa High-Entropy Alloy is carefully handled during storage and transportation to preserve the quality of our product in its original condition. Alfa Chemistry Materials 3
TJ-M2010-5 TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain of MyD88 to interfere with its homodimerization, and the TLR/MyD88 signal pathway[1][2]. TJ-M2010-5 can be used for the research of myocardial ischemia/reperfusion injury (MIRI)[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1357471-57-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139397. MedChemExpress MCE
TK05 TK05 is a potent and selective inhibitor of leukotriene C 4 synthase (LTC4S) with an IC 50 of 95 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1245734-61-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117143. MedChemExpress MCE
TK-129 TK-129 is an orally active, low-toxicity, potent KDM5B inhibitor (with high affinity; IC50=44 nM). TK-129 exerts cardioprotective effects by inhibiting KDM5B and blocking the KDM5B-associated Wnt pathway. TK-129 reduces ang II-induced activation of cardiac fibroblasts in vitro and reduces isoprenaline-induced myocardial remodelling and fibrosis in vivo. TK-129 can be used in studies of cardiovascular disease[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3031476-73-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151483. MedChemExpress MCE
TK216 TK216 is an orally active and potent E26 transformation specific (ETS) inhibitor[1]. TK216 directly binds EWS-FLI1 and inhibits EWS-FLI1 protein interactions. TK216 blocks the binding between EWS-FLI1 and RNA helicase A. TK216 has anticancer activity[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1903783-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122903. MedChemExpress MCE
TKIM TKIM is a TREK-1 channel inhibitor with an IC 50 of 2.96 μM. TKIM binds to the pocket of the intermediate (IM) state of TREK-1 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 326921-25-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-134559. MedChemExpress MCE
TL02-59 TL02-59 is an orally active, selective Src-family kinase Fgr inhibitor with an IC 50 of 0.03 nM. TL02-59 inhibits Lyn and Hck with IC 50 s of 0.1 nM and 160 nM, respectively. TL02-59 potently suppresses acute myelogenous leukemia (AML) cell growth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1315330-17-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112852. MedChemExpress MCE
TL-119 TL-119 is an antibiotic isolated from Bacillus subtilis. It is effective against gram-positive bacteria and fungi. Synonyms: Antibiotic TL-119; TL 119. CAS No. 55599-68-3. Molecular formula: C42H57N7O9. Mole weight: 803.9. BOC Sciences 12
TL-1A human recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
TL8-506 TL8-506 is a specific TLR8 agonist with an EC50 of 30?nM. TL8-506 has immunomodulatory effects and can be used in the study of tuberculosis and cancer immunotherapy[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1268163-15-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-20457. MedChemExpress MCE
TL-895 TL-895 is a potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor with an IC 50 and a K i of 1.5 nM and 11.9 nM, respectively [1]. TL-895 is used be for JAKi-relapsed/refractory myelofibrosis, acute myeloid leukemia, COVID-19 and cancer research [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1415823-49-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139481. MedChemExpress MCE
TLC disialoganglioside mixture TLC disialoganglioside mixture. Group: Others. Appearance: Liquid. Storage: -20°C. Source: Bovine. TLC disialoganglioside mixture; TLC; Disialoganglioside Mixture; lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-124. Creative Enzymes
TLC gangliotetraosylceramide & sialosyl derivatives mixture TLC gangliotetraosylceramide & sialosyl derivatives mixture. Group: Others. Appearance: Liquid. Storage: -20°C. Source: Bovine. TLC gangliotetraosylceramide & sialosyl derivatives mixture; TLC; Gangliotetraosylceramide & Sialosyl Derivatives Mixture; lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-126. Creative Enzymes
TLCK-treated Chymotrypsin TLCK-treated Chymotrypsin is a serine protease. Chymotrypsin cleaves protein chains at the carboxyl side of aromatic amino acids. TLCK treated to inactivate residual tryspin activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9004-7-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108910B. MedChemExpress MCE
TLC lactosylceramides and sialosyl derivatives mixture TLC lactosylceramides and sialosyl derivatives mixture. Group: Others. Appearance: Liquid. Storage: -20°C. Source: Bovine. TLC lactosylceramides and sialosyl derivatives mixture; TLC; Lactosylceramides & Sialosyl Derivatives Mixture; lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-125. Creative Enzymes
TLC monosialoganglioside mixture TLC monosialoganglioside mixture. Group: Others. Appearance: Liquid. Storage: -20°C. Source: Bovine and human. TLC monosialoganglioside mixture; TLC; Monosialoganglioside Mixture; lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-123. Creative Enzymes
TLC neutral glycosphingolipid mixture TLC neutral glycosphingolipid mixture. Group: Others. Appearance: Liquid. Storage: -20°C. Source: Bovine and porcine. TLC neutral glycosphingolipid mixture; TLC; Neutral Glycosphingolipid Mixture (TLC)(qualmixture); lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-122. Creative Enzymes
TLC non-polar lipid mixture-1 TLC non-polar lipid mixture-1. Group: Others. Appearance: Liquid. Storage: -20°C. Source: Plant, ovine. TLC non-polar lipid mixture-1; TLC; Non-Polar Lipid Mixture A (quantitative); lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-103. Creative Enzymes
TLC non-polar lipid mixture-2 TLC non-polar lipid mixture-2. Group: Others. Appearance: Liquid. Storage: -20°C. Source: Plant, ovine. TLC non-polar lipid mixture-2; TLC; Non-Polar Lipid Mixture B (quantitative); lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-104. Creative Enzymes
TLC polar lipid mixture TLC polar lipid mixture. Group: Others. Appearance: Liquid. Storage: -20°C. Source: Natural, egg, ovine. TLC polar lipid mixture; TLC; Polar Lipid Mixture (quantitative); lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-101. Creative Enzymes
TLC sphingolipid mixture TLC sphingolipid mixture. Group: Others. Appearance: Liquid. Storage: -20°C. Source: Bovine. TLC sphingolipid mixture; TLC; Sphingolipid Mixture (quantitative); lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-102. Creative Enzymes
TLK1, active, GST tagged human recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
TLK2 (388-end), active, GST tagged human recombinant, expressed in baculovirus infected Sf9 cells, ?80% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
TLQP 21 TLQP 21 is a VGF-derived peptide. TLQP 21 has been shown to protect cerebellar granule cells (CGCs) from serum and potassium deprivation-induced apoptosis. TLQP 21 has the potential for the prevention of early phase diet-induced diabetes. Synonyms: TLQP 21; TLQP21; TLQP-21. Grade: ≥95%. CAS No. 869988-94-3. Molecular formula: C107H170N40O26. Mole weight: 2432.7. BOC Sciences
TLQP 21 TLQP 21. Group: Biochemicals. Grades: Purified. CAS No. 869988-94-3. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 5
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TLQP-21 (human) TLQP-21 (human). Synonyms: H-Thr-Leu-Gln-Pro-Pro-Ser-Ala-Leu-Arg-Arg-Arg-His-Tyr-His-His-Ala-Leu-Pro-Pro-Ser-Arg-OH; L-Threonyl-L-leucyl-L-glutaminyl-L-prolyl-L-prolyl-L-seryl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-arginyl-L-histidyl-L-tyrosyl-L-histidyl-L-histidyl-L-alanyl-L-leucyl-L-prolyl-L-prolyl-L-seryl-L-arginine. Grade: ≥95%. CAS No. 1259837-37-0. Molecular formula: C110H176N40O27. Mole weight: 2490.83. BOC Sciences 11
TLQP-30 TLQP-30 is a VGF peptide. Synonyms: Thr-Leu-Gln-Pro-Pro-Ala-Ser-Ser-Arg-Arg-Arg-His-Phe-His-His-Ala-Leu-Pro-Pro-Ala-Arg-His-His-Pro-Asp-Leu-Glu-Ala-Gln-Ala; L-Alanine, L-threonyl-L-leucyl-L-glutaminyl-L-prolyl-L-prolyl-L-alanyl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-arginyl-L-histidyl-L-phenylalanyl-L-histidyl-L-histidyl-L-alanyl-L-leucyl-L-prolyl-L-prolyl-L-alanyl-L-arginyl-L-histidyl-L-histidyl-L-prolyl-L-α-aspartyl-L-leucyl-L-α-glutamyl-L-alanyl-L-glutaminyl-. Grade: ≥95%. CAS No. 922704-13-0. Molecular formula: C150H232N54O40. Mole weight: 3431.78. BOC Sciences 11
TLR1 TLR1 (compound 4a) is a low molecular weight, cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic. TLR1 inhibits IL-1 receptor-mediated responses [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 566914-00-9. Pack Sizes: 500 μg (33 mM * 50 μL in Ethanol); 1 mg (33 mM * 100 μL in Ethanol). Product ID: HY-W011400. MedChemExpress MCE
TLR1/TLR2 Antagonist, CU-CPT22 (Hexyl-3,4,6-trihydroxy-2-methoxy-5-oxo-5H-benzo[7]annulene-8-carboxylate) A cell-permeable benzotropolone compound that competes against Pam3CSK4- for TLR1/TLR2 heterodimer binding (Ki = 410nM) and selectively antagonizes against Pam3CSK4-induced RAW264.7 cellular NO production (IC50 = 580nM) without apparent cytotoxicity (up to 100uM and 24h). Exhibits no antagonist activity toward TLR2/TLR6, TLR3, TLR4, TLR7 at 0.5uM and little inhibitory potency against a panel of 10 kinases at 5uM (by <11% inhibition). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??O?. US Biological Life Sciences. USBiological 4
Worldwide
TLR2-IN-C29 TLR2-IN-C29 is an inhibitor of TLR2/1 and TLR2/6 signaling. It is induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TLR2-IN-C29; TLR2 IN C29; TLR2INC29; TLR2-inhibitor-C29; TLR2 inhibitor-C29; TLR2 inhibitor C29. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 363600-92-4. Molecular formula: C16H15NO4. Mole weight: 285.29. Purity: >98%. IUPACName: 3-[[(2-Hydroxy-3-methoxyphenyl)methylene]amino]-2-methyl-benzoic acid. Canonical SMILES: O=C(O)C1=CC=CC(/N=C/C2=CC=CC(OC)=C2O)=C1C. Product ID: ACM363600924. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
TLR3, Control Peptide (Toll Like Receptor 3) TLR3, Control Peptide (Toll Like Receptor 3). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences. USBiological 1
Worldwide
TLR3/dsRNA Complex Inhibitor (CU CPT 4a; Toll-Like Receptor 3/Double Strand RNA Complex Inhibitor; (R) -2- (3-Chloro-6-fluorobenzo [b]thiophene-2-carboxamido) -3-phenylpropanoic Acid) A thiophene carboxamidopropionate compound that acts as a direct, competitive and high affinity inhibitor of dsRNA binding to TLR3 (Ki=2.96uM; =19nM for dsRNA binding to TLR3) and selectively antagonizes stimulated TLR3 signaling without affecting TLR1/2, TLR2/6, TLR4 and TLR7 pathways. Shown to efficiently repress TNF-a and IL-1b (IC90=27uM) and NO production (IC50=3.44uM) in Poly(I:C)-induced RAW 264.7 macrophages. Exhibits minimal cytotoxicity (IC50>100uM in RAW 264.7 cells) and is weakly active against a panel of 12-representative kinases and 4-cytochrome enzymes (in vitro assays). Group: Biochemicals. Alternative Names: (R) -2- (3-Chloro-6-fluorobenzo [b]thiophene-2-carboxamido) -3-phenylpropanoic Acid; CU CPT 4a. Grades: Highly Purified. CAS No. 1279713-77-7. Pack Sizes: 10mg. Molecular Formula: C18H13ClFNO3S, Molecular Weight: 377.8. US Biological Life Sciences. USBiological 4
Worldwide
TLR-3 human recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
TLR4-IN-C34 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
TLR4-IN-C34 TLR4-IN-C34 is an orally active TLR4 inhibitor and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 40592-88-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107575. MedChemExpress MCE
TLR4 Inhibitor, TAK-242 (Ethyl- (6R) -6- (N- (2-chloro-4-fluorophenyl) sulfamoyl) cyclohex-1-ene-1-carboxylate) A cell-permeable cyclohexenecarboxylate that disrupts TLR4, but not TLR1-3 or TLR5-10, interaction with adaptor molecules TIRAP and TRAM via direct binding to TLR4 intracellular Cys747 residue.Shown to effectively inhibit TLR4-mediated cellular events (IC50 = 1.8, 1.3, and 1.9nM, respectively, against LPS-induced NO, IL-6, and TNF-alpha production in murine RAW264.7 macrophages) in vitro and completely prevent LPS- (7mg/kg, i.p.) induced death in mice (3mg/kg; i.v.) in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 243984-11-4. Pack Sizes: 5mg. Molecular Formula: C??H??ClFNO?S, Primary Target: TLR4. US Biological Life Sciences. USBiological 4
Worldwide
TLR7/8/9-IN-1 TLR7/8/9-IN-1 is a potent and orally bioavailable small molecule antagonist (IC50 = 43 nM) of Toll-like receptors 7/8/9 (TLR7/8/9). Uses: Scientific research. Group: Signaling pathways. CAS No. 2180127-82-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131952. MedChemExpress MCE
TLR7/8 agonist 1 TLR7/8 agonist 1 is a toll-like receptor ( TLR7 )/ TLR8 dual-agonistic imidazoquinoline. Uses: Scientific research. Group: Signaling pathways. CAS No. 1258457-59-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103698. MedChemExpress MCE
TLR7/8 agonist 1 dihydrochloride TLR7/8 agonist 1 dihydrochloride is a toll-like receptor TLR7/TLR8 dual-agonistic imidazoquinoline [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1620278-72-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103698A. MedChemExpress MCE
TLR7/8 agonist 4 TLR7/8 agonist 4 (compound 41) is a potent TLR7/8 agonist. TLR7/8 agonist 4 has anti-cancer activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2388520-33-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139017. MedChemExpress MCE
TLR7/8 agonist 8 TLR7/8 agonist 8 (compound 24m) is a potent toll-like receptor 7/8 (TLR7/8) dual agonist, with EC 50 s of 27 and 12 nM for hTLR7 and hTLR8 , respectively. TLR7/8 agonist 8 can improve the antitumor activity of PD-1/PD-L1 blockade [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2649170-16-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-153543. MedChemExpress MCE
TLR7 agonist 1 TLR7 agonist 1 is a potent, selective and oral TLR7 agonist with an IC 50 of 90 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 2178156-33-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111358. MedChemExpress MCE
TLR9-IN-1 TLR9-IN-1 is a potent and selective TLR9 inhibitor with an IC50 value of 7 nM for human TLR9. TLR9-IN-1 can be used for researching diseases associated with undesirable immune response[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2226366-86-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148045. MedChemExpress MCE
TM-1 TM-1 is a potent inhibitor of pyruvate dehydrogenase kinase ( PDHK1 ). TM-1 inhibits PDHK1 and PDHK2 with IC 50 s of 2.97 μM and 5.2 μM, respectively. TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation, and inhibits cell proliferation [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 921099-13-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-136882. MedChemExpress MCE
Tm3PyP26PyB Tm3PyP26PyB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3,5-Tris(6-(3-(pyridin-3-yl)phenyl)pyridin-2-yl)benzene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1492917-78-8. Molecular formula: C54H36N6. Mole weight: 768.9 g/mol. Product ID: ACM1492917788. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
TM5275 sodium TM5275 sodium is a plasminogen activator inhibitor (PAI-1) with an IC50 of 6.95 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 1103926-82-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100447. MedChemExpress MCE
TM5275 sodium salt ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
TM5441 TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1), has IC50 values between 13.9 and 51.1 ?M and induces intrinsic apoptosis in several human cancer cell lines. TM5441 attenuates N?-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1190221-43-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101761. MedChemExpress MCE
TMAD TMAD. Group: Biochemicals. Alternative Names: 1,1'-Azobis(N,N'-dimethylformamide); N, N, N', N'-Tetra methyl azodicarboxamide. Grades: Highly Purified. CAS No. 10465-78-8. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C6H12N4O2. US Biological Life Sciences. USBiological 8
Worldwide
TMA-DPH TMA-DPH is a hydrophobic fluorescent membrane probe (Ex=355 nm; Em=430 nm). TMA-DPH is able to anchor on the cell surface and localize to different regions of the phospholipid bilayer. By analyzing the fluorescence polarization values of TMA-DPH in the plasma membrane and membrane substructures, the fluidity of the cell membrane can be determined [1] [2] [3]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 115534-33-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D0986. MedChemExpress MCE
TMAH Tetramethylammonium hydroxide is a solid in the hydrated form or a colorless liquid with a strong ammonia-like odor. It is soluble in water. It is corrosive to metals and tissue.;Liquid. Group: Polymers. CAS No. 75-59-2. Product ID: tetramethylazanium; hydroxide. Molecular formula: 91.15g/mol. Mole weight: C4H13NO. C[N+](C)(C)C.[OH-]. InChI=1S/C4H12N.H2O/c1-5(2, 3)4;/h1-4H3;1H2/q+1;/p-1. WGTYBPLFGIVFAS-UHFFFAOYSA-M. Alfa Chemistry Materials 3
TMAH-22 (Tetramethylammonium hydroxide aq. solution) TMAH-22 (Tetramethylammonium hydroxide aq. solution). Group: Acids and alkalis. CAS No. 75-59-2. Alfa Chemistry Materials 3

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