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| Product | Description | |
|---|---|---|
| Tonabersat. | Tonabersat. Group: Biochemicals. Alternative Names: N-[(3S,4S)-6-Acetyl-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-3-chloro-4-fluoro-benzamide; (3S-cis)-N-(6-acetyl-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl)-3-chloro-4-fluorobenzamide; SB 220453. Grades: Highly Purified. CAS No. 175013-84-0. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Tonabersat-d6 | Tonabersat-d6. Group: Biochemicals. Alternative Names: N-[(3S,4S)-6-Acetyl-3,4-dihydro-3-hydroxy-2,2-(dimethyl-d6)-2H-1-benzopyran-4-yl]-3-chloro-4-fluorobenzamide; (3S-cis)-N-(6-acetyl-3,4-dihydro-3-hydroxy-2,2-(dimethyl-d6)-2H-1-benzopyran-4-yl)-3-chloro-4-fluorobenzamide; SB 220453-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Tonalide | Used for non-alcoholic perfumes. Group: Biochemicals. Alternative Names: 1-(5,6,7,8-Tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthalenyl)-ethanone;5',6',7',8'-Tetrahydro-3',5',5',6',8',8'-hexamethyl-2'-acetonaphthone; AHMT (perfume); Extralide; Fixolide; NSC 19550. Grades: Highly Purified. CAS No. 21145-77-7. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Tongkat Ali Extract | Tongkat Ali Extract. Applications: Tongkat ali extract can be used in functional food, drinks, health care products and pharmaceuticals. Group: Others. Purity: 10:1, 100:1, 200:1 as required. Appearance: Brown powder. Tongkat Ali Extract. Cat No: EXTC-204. |  |
| Tonsil Microvascular Endothelial Cells, Human (Frozen) | Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| Tonsil Microvascular Endothelial Cells, Human (T-25 flask) | Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. | Worldwide |
| TOOS (3-(N-Ethyl-3-methylanilino)-2-hydroxypropanesulfonic acid sodiumsalt) | 1g Pack Size. Group: Analytical Reagents, Biochemicals, Stains & Indicators. Formula: C12H18NNaO4S. CAS No. 82692-93-1. Prepack ID 60478758-1g. Molecular Weight 295.33. See USA prepack pricing. |  |
| Toosendanin | Toosendanin is a natural diterpenoid compound found in the barks of Melia toosendan Sieb. et Zucc. Toosendanin shows hepatotoxicity and is also an effective insecticide for Ae. Synonyms: 24-Norchola-20,22-diene-4-carboxaldehyde,3,12-bis(acetyloxy)-14,15:21,23-diepoxy-1,7,19-trihydroxy-4,8-dimethyl-11-oxo-,cyclic4,19-hemiacetal, [C(R),1α,3α,4β, 5α,7α,12α,13α,14β,15β,17α]-; Chuanliansu; 28-Deacetylsendanin; 12-AcetoxyaMoorastatin. Grade: >98%. CAS No. 58812-37-6. Molecular formula: C30H38O11. Mole weight: 574.62. |  |
| Toosendanin | Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb. et Zucc., possesses analgesic, insecticidal and anti-inflammatory activities [1]. Uses: Scientific research. Group: Natural products. CAS No. 58812-37-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0263. |  |
| Toosendanin | Toosendanin is a triterpenoid derivative, acts as a novel agonist of L-type Ca2+ channels in neonatal rat ventricular cells. Group: Biochemicals. Alternative Names: [C(R), 1α, 3α, 4 β, 5α, 7α, 12α, 13α, 14 β,15 β,17α]-3,12-Bis(acetyloxy)-14,15:21,23-diepoxy-1,7,19-trihydroxy-4,8-dimethyl-11-oxo-24-Norchola-20,22-diene-4-carboxaldehyde Cyclic 4,19-Hemiacetal; 14, 15-Epoxy-4, 10- (methanoxymethano) -1H-cyclopenta [a]phenanthrene, 24-Norchola-20,22-diene-4-carboxaldehyde Deriv.; 28-Deacetylsendanin; Chuanliansu. Grades: Highly Purified. CAS No. 58812-37-6. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Toosendanin (Chuanliansu, 12-Acetoxyamoorastatin) | Toosendanin (Chuanliansu, 12-Acetoxyamoorastatin). Group: Biochemicals. Alternative Names: Chuanliansu; 12-Acetoxyamoorastatin. Grades: Plant Grade. CAS No. 58812-37-6. Pack Sizes: 20mg. Molecular Formula: C30H38O11, Molecular Weight: 574.615999999999. US Biological Life Sciences. | Worldwide |
| TopFluor(R)-PGPE | TopFluor(R)-PGPE. Group: Others. Purity: >99%. Mole weight: 900.834. Stability: 1 Years. Storage: -20°C. 1-Palmitoyl-2-glutaroyl-sn-glycero-3-phosphoethanolamine-N-[4-(dipyrrometheneboron difluoride)butanoyl] (ammonium salt); PGPE. Cat No: PHOZ-018. | |
| TopFluor(R)-POVPE (DMA) | TopFluor(R)-POVPE (DMA). Group: Others. Purity: >99%. Mole weight: 930.903. Stability: 1 Years. Storage: -20°C. 1-Palmitoyl-2-(5,5-dimethoxyvaleroyl)-sn-glycero-3-phosphoethanolamine-N-[4-(dipyrrometheneboron difluoride)butanoyl] (ammonium salt); POVPE (DMA). Cat No: PHOZ-019. | |
| Topiramate | Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels , increases in potassium conductance, and inhibition of carbonic anhydrase [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: McN 4853; RWJ 17021. CAS No. 97240-79-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0122. | |
| Topiramate | Topiramate is a kainate GluR5 receptor antagonist, originally used as an anticonvulsant. Synonyms: 2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate. Grade: >98%. CAS No. 97240-79-4. Molecular formula: C12H21NO8S. Mole weight: 339.37. | |
| Topiramate-[13C6] | An isotope labelled of Topiramate. Topiramate is an anticonvulsant drug. Synonyms: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl-3a,5,5a,8a,8b-13C5)methyl-13C sulfamate. Grade: 98% by CP. CAS No. 1217455-55-4. Molecular formula: C6[13C]6H21NO8S. Mole weight: 345.32. | |
| Topiramate-[d12] | An isotope labelled form of Topiramate. Topiramate is an anticonvulsant drug. It can be used for the treatment of epilepsy. Synonyms: 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fuctopyranose-d12 1-Sulfamate; Epitoma-d12; Epitomax-d12; McN 4853-d12; RWJ 17021-d12; TPM-d12; Topamac-d12; Topamax-d12; Topimax-d12; Topina-d12; Topomax-d12. Grade: 98% by HPLC; 99% atom D. CAS No. 1279037-95-4. Molecular formula: C12H9D12NO8S. Mole weight: 351.44. | |
| Topiramate-D12 solution | 100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms). |  |
| Topiramate EP Impurity C | Topiramate EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106881-41-8. Molecular formula: C9H17NO8S. Mole weight: 299.29. Catalog: APB106881418. | |
| Topiramate Impurity 12 | Topiramate Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106881-42-9. Molecular formula: C6H13NO8S. Mole weight: 259.23. Catalog: APB106881429. | |
| Topiramate Impurity 16 | Topiramate Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10489-81-3. Molecular formula: C6H12O6. Mole weight: 180.16. Catalog: APB10489813. | |
| Topiramate Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Topiroxostat | Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC 50 value of 5.3 nM and a K i value of 5.7 nM. Topiroxostat exhibits weak CYP3A4 -inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FYX-051. CAS No. 577778-58-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14874. | |
| TOPK, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Topo I (197-651) (core domain) human | recombinant, expressed in insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Topo I (C651-765) (C terminal domain) human | recombinant, expressed in insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Topo I (N1-197) (NTD) human | recombinant, expressed in insect cells, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Topoisomerase I from E. coli, Recombinant | Topoisomerase I relaxes supercoiled DNA molecules. The enzyme initiates transient breakages and rejoins of phosphodiester bonds in superhelical turns of closed-circular DNA. Enzyme activity is independent of right-and left-handed superhelices. Topoisomerase i (e. coli) catalyzes the relaxation of negatively supercoiled dna. topoisomerase i has also been implicated in knotting and unknotting dna and in linking complementary rings of single-stranded dna into double-stranded rings. the intact holoenzyme is a 97 kda protein. Group: Enzymes. Synonyms: Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. TOPO I. Storage: at -20°C. Form: 50 mM KCl, 10 mM Tris-HCl (pH 7.5), 35 mM (NH4)2SO4, 0.1 mM EDTA, 1 mM DTT and 50% glycerol. Source: E. coli. Species: E. coli. Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. Cat No: NATE-1339. | |
| Topoisomerase I from Human, Recombinant | Topoisomerase I relaxes supercoiled DNA molecules. The enzyme initiates transient breakages and rejoins of phosphodiester bonds in superhelical turns of closed-circular DNA. Enzyme activity is independent of right-and left-handed superhelices. Group: Enzymes. Synonyms: Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. TOPO I. Stability: Stable for 3 months undiluted. Storage: Store at -80°C. It is recommended that the enzyme is aliquoted to avoid repeated freeze-thaw cycles. Source: Baculovirus-infected insect cells (Spodoptera frugiperda). Species: Human. Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. Cat No: NATE-1340. | |
| Topoisomerase II-alpha-b (828-836) | Topoisomerase II-alpha-b (828-836) is a peptide derived from Topoisomerase II-alpha-b. Topoisomerase II-alpha is an enzyme that controls and alters the topologic states of DNA during transcription. Human topoisomerase II enzymes are targets for a number of widely used anticancer agents. | |
| Topoisomerase II inhibitor 14 | Topoisomerase II inhibitor 14 (compound 2f) is a potent inhibtor of Topoisomerase II, with anticancer activity. Topoisomerase II inhibitor 14 induces apoptosis, and arrests cell cycle at S phase. Topoisomerase II inhibitor 14 exhibits antioxidant effect and decreases the level of GSH, MDA, and NO [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 305343-00-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W278582. | |
| Topoisomerase II Inhibitor (BNS-22) | A potent, 2H-chromen-2-one small molecule inhibitor that is selective for TOP2 (IC50=2.8uM and 0.42uM for TOP2a and TOP2b, respectively). Unlike TOP2 poisons such as etoposide, it does not lead to DNA damage associated with DNA Double-Strand Breaks, as evidenced by the lack of y-H2AX accumulation but instead inhibits kinetoplast DNA decatenation in vitro. This compound affects cell cycle at the M phase and disturbs mitotic spindle formation in HeLa cells at 3-10uM. It also exhibits significant anti-proliferative activities against several human cancer cell lines. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Topoisomerase II Inhibitor, BNS-22 | The Topoisomerase II Inhibitor, BNS-22 controls the biological activity of Topoisomerase. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy. | |
| Topoisomerase II? Inhibitor, TSC24 | The Topoisomerase II? Inhibitor, TSC24 controls the biological activity of Topoisomerase. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy. | |
| Topo I (Y723F) (mt Y723F) human | recombinant, expressed in insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Topopyrone A | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone A selectively inhibits topoisomerase I with the IC50 of 1.22 ng/mL. It also has anti-Gram-positive bacteria activity. Molecular formula: C18H9ClO7. Mole weight: 372.71. | |
| Topopyrone B | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone B selectively inhibits topoisomerase I with the IC50 of 0.15 ng/mL. It also has anti-Gram-positive bacteria activity and it has a strong inhibitory effect on herpes virus, especially varicella zoster virus (VZV). Molecular formula: C18H9ClO7. Mole weight: 372.71. | |
| Topopyrone C | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone C selectively inhibits topoisomerase I with the IC50 of 4.88 ng/mL. It also has anti-Gram-positive bacteria activity. Molecular formula: C18H10O7. Mole weight: 338.27. | |
| Topopyrone D | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone A selectively inhibits topoisomerase I with the IC50 of 19.63 ng/mL. Molecular formula: C18H10O7. Mole weight: 338.27. | |
| Topostatin | Topostatin is originally isolated from Thermomonos pora alba No. 1520. It has inhibitory effects on human tumor cells, and the IC50 of SNB-75 and SNB-78 were 0.4 μmol/L and 7 μmol/L, respectively. Molecular formula: C36H58N4O11S. Mole weight: 754.93. | |
| Topotecan | Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. It has also been used for in vitro apoptosis assays in PA317 cells. Synonyms: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, (4S)-; (4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, (S)-; (S)-Topotecan; 10-Hydroxy-9-[(dimethylamino)methyl]-(20S)-camptothecin; 9-(N,N-Dimethylaminomethyl)-10-hydroxycamptothecin; Evotopin; Hycamptamine; Hycamptin; Nogitecan; NSC 609699; Potactasol; SKF 104864; SKF-S 104864; TopoCED; Topophore C; Topotecan lactone; ZINC 1611274. Grade: ≥95%. CAS No. 123948-87-8. Molecular formula: C23H23N3O5. Mole weight: 421.45. | |
| Topotecan | Topotecan (SKF 104864A; NSC 609669) is an orally active and potent Topoisomerase I inhibitor. Topotecan induces cell cycle arrest in G0/G1 and S phases and promotes apoptosis. Topotecan shows anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF 104864A; NSC 609669. CAS No. 123948-87-8. Pack Sizes: 1 mg. Product ID: HY-13768. | |
| Topotecan carboxylic acid sodium salt | Topotecan carboxylic acid sodium salt. Group: Biochemicals. Alternative Names: 1-[ (Dimethylamino)methyl]-a-ethyl-9, 11-dihydro-a, 2-dihydroxy-8- (hydroxymethyl)-9-oxo-indolizino[1, 2-b]quinoline-7-acetic acid. Grades: Highly Purified. CAS No. 123949-08-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C23H24N3NaO6. US Biological Life Sciences. | Worldwide |
| Topotecan-d5 | Labeled Topotecan. A DNA topoisomerase I inhibitor; semisynthetic analog of Camptothecin. Antineoplastic. Group: Biochemicals. Alternative Names: (4S)-10-[ (Dimethylamino)methyl]-4- (ethyl-d5)-4, 9-dihydroxy-1H-pyrano[3, 4, 6-7]indolizino[1, 2-b]quinoline-3, 14 (4H, 12H)-dione; NSC-609669-d5; SKF-104864A-d5; Hycamtin-d5. Grades: Highly Purified. CAS No. 1133355-98-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Topotecan-[d5] | Topotecan-[d5] is the labelled analogue of Topotecan. Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. Uses: Labelled topotecan (t542500). a dna topoisomerase i inhibitor; semisynthetic analog of camptothecin. antineoplastic. Synonyms: Topotecan D5. Grade: 95% atom D. CAS No. 1133355-98-2. Molecular formula: C23H18D5N3O5. Mole weight: 426.48. | |
| Topotecan-d6 | Topotecan-d6 is the deuterium labeled Topotecan. Topotecan (SKF 104864A; NSC 609669) is a Topoisomerase I inhibitor. The IC50 values of Topotecan at 24 h are 2.73±0.25 μM of U251 cells, 2.95±0.23 μM of U87 cells, 5.46±0.41 μM of GSCs-U251 and 5.95 μM of GSCs-U87. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (4S)-10-[(Dimethylamino-d6)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4',6-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; NSC-609669-d6; SKF-104864A-d6; Hycamtin-d6. Product Category: Inhibitors. Appearance: Yellow Solid. CAS No. 1044904-10-0. Molecular formula: C23H17D6N3O5. Mole weight: 427.48. Purity: 0.96. IUPACName: Topotecan-d6. Canonical SMILES: CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O. Product ID: ACM1044904100. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Topotecan-d6 | Labelled Topotecan, a DNA topoisomerase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1044904-10-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Topotecan-[d6] | One isotopic labelled form of Topotecan, which is a topoisomerase I inhibitor and has been found to be an effective antineoplastic agent. Synonyms: (4S)-10-[(Dimethylamino-d6)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4',6-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; NSC-609669-d6; SKF-104864A-d6; Hycamtin-d6. Grade: 95% by HPLC; 98% atom D. CAS No. 1044904-10-0. Molecular formula: C23H17D6N3O5. Mole weight: 427.48. | |
| Topotecan HCl | Topotecan HCl. Group: Biochemicals. Alternative Names: (4S)-10-[ (Dimethylamino)methyl]-4-ethyl-4, 9-dihydroxy-1H-pyrano[3', 4', 6-7]indolizino[1, 2-b]quinoline-3, 14 (4H, 12H)-dione hydrochloride; NSC-609669; SKF-104864A. Grades: Highly Purified. CAS No. 119413-54-6. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C23H24ClN3O5. US Biological Life Sciences. | Worldwide |
| Topotecan hydrochloride | Topotecan Hydrochloride (SKF 104864A Hydrochloride) is a Topoisomerase I inhibitor with potent antineoplastic activities. Uses: Scientific research. Group: Natural products. Alternative Names: SKF 104864A hydrochloride; NSC 609669 hydrochloride. CAS No. 119413-54-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13768A. | |
| Topotecan hydrochloride | Topotecan hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 119413-54-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Topotecan hydrochloride | Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. Uses: Topoisomerase i inhibitors. Synonyms: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, hydrochloride (1:1), (4S)-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (4S)-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (S)-; (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[l,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride; Hycamtin; Nogitecan hydrochloride; NSC 609669; SKF 104864A; SKFS 104864A; Topotecan chlorohydrate; Xinze. Grade: >98%. CAS No. 119413-54-6. Molecular formula: C23H24ClN3O5. Mole weight: 457.91. | |
| Topotecan hydrochloride | Topotecan Hydrochloride (SKF 104864A Hydrochloride) is a Topoisomerase I inhibitor with potent antineoplastic activities. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,4-Di[4-(3-phenoxypropoxy)-2-butynyl]piperazine. Product Category: Inhibitors. Appearance: Light-yellow powder. CAS No. 119413-54-6. Molecular formula: C23H24ClN3O5. Mole weight: 457.91. Purity: 0.98. IUPACName: (19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride. Canonical SMILES: CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O.Cl. Product ID: ACM119413546. Alfa Chemistry ISO 9001:2015 Certified. | |
| Topotecan Hydrochloride | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardschiral moleculesenzyme activators, inhibitors & substrates. Alternative Names: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (S)-, Hycamtin, SKF-S-104864-A, (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[l,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride, 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (4S)- (9CI), Nogitecan hydrochloride, Topotecan hydrochloride, SKFS 104864A, Xinze, SKF-S-104864,(4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione Hydrochloride (1:1), SKF 104864A, Topotecan chlorohydrate, SKF-S-106567, NSC 609669. | |
| Topotecan, Hydrochloride ( (4S)-10-[ (Dimethylamino)methyl]-4-ethyl-4, 9-dihydroxy-1H-pyrano[3, 4, 6-7]indolizino[1, 2-b]quinoline-3, 14 (4H, 12H)-dione, Hydrochloride, SKF-104864A,) | A DNA topoisomerase inhibitor. Group: Biochemicals. Alternative Names: (4S)-10-[ (Dimethylamino)methyl]-4-ethyl-4, 9-dihydroxy-1H-pyrano[3, 4, 6-7]indolizino[1, 2-b]quinoline-3, 14 (4H, 12H)-dione, Hydrochloride, SKF-104864A. Grades: Highly Purified. CAS No. 119413-54-6. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Topotecan hydrochloride hydrate | ?98% (HPLC and enzymatic). Group: Fluorescence/luminescence spectroscopy. | |
| Topotecan Hydrochloride Liposome (PEGylated) | Topotecan Hydrochloride (TPT) is a semi-synthetic derivative of the plant alkaloid camptothecin (CPT) with cytotoxic properties. Like other drugs in the CPT family, TPT is a specific inhibitor of topoisomerase I, causing lethal DNA damage in the S phase of mitosis. Liposome preparation and anti-tumor activity research. This product is a pre-formulated liposome encapsulating Topotecan Hydrochloride. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. |  |
| Topotecan Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Topotecan Related Compound C | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Topramezone | analytical standard. Group: Pesticides & metabolites standardspesticides & metabolitespesticides & metabolites. | |
| TO-PRO-3 iodide | TO-PRO-3 iodide is a highly efficient blue fluorescent dye that can stain cytoplasm as a cell tracer. Uses: Scientific research. Group: Fluorescent dye. CAS No. 157199-63-8. Pack Sizes: 671 μg (5 mM * 200 μL in DMSO). Product ID: HY-117070. | |
| TOPS | TOPS is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 40567-80-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15933. | |
| Torachrysone | Torachrysone is a natural phenol isolated from the seeds of Cassia obtusifolia. Synonyms: 2-Acetyl-3-methyl-6-methoxynaphthalene-1,8-diol. Grade: >97%. CAS No. 22649-04-3. Molecular formula: C14H14O4. Mole weight: 246.3. | |
| Torachrysone | Torachrysone. Group: Biochemicals. Grades: Highly Purified. CAS No. 22649-04-3. Pack Sizes: 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| Torachrysone 8-O-glucoside | Torachrysone 8-O-glucoside is a natural compound found in the rhizoma of Rheum officinale L. For its inhibitory activities of alpha-glucosidase, it may be used for the treatment of type 2 diabetes. Uses: Anti-diabetes. Synonyms: 7-Acetyl-8-hydroxy-3-methoxy-6-methyl-1-naphthyl β-D-glucopyranos ide. Grade: >98%. CAS No. 64032-49-1. Molecular formula: C20H24O9. Mole weight: 408.40. | |
| Torasemide | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C16H20N4O3S. CAS No. 56211-40-6. Prepack ID 86431125-1g. Molecular Weight 348.42. See USA prepack pricing. | |
| Torasemi impurity 11 | Torasemi impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106944-62-1. Molecular formula: C16H20N4O3S. Mole weight: 348.42. Catalog: APB106944621. | |
| Torasemi impurity 12 | Torasemi impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106944-63-2. Molecular formula: C16H20N4O3S. Mole weight: 348.42. Catalog: APB106944632. | |
| Torcetrapib | Torcetrapib (CP-529414) is a selective, potent cholesteryl ester transfer protein ( CETP ) inhibitor. A typical inhibition curve for whole human plasma, having a CETP concentration of 37 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-529414. CAS No. 262352-17-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-12089. | |
| Torcetrapib | Cholesteryl ester transfer protein (CETP) inhibitor. Antilipemic; antiatherosclerotic. Group: Biochemicals. Alternative Names: (2R, 4S) -4-[[[3, 5-Bis (trifluoromethyl) phenyl]methyl] (methoxycarbonyl) amino]-2-ethyl-3, 4-dihydro-6- (trifluoromethyl) -. Grades: Highly Purified. CAS No. 262352-17-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
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