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| Product | Description | |
|---|---|---|
| TP 003 | TP 003. Group: Biochemicals. Grades: Purified. CAS No. 628690-75-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| TP-020 | TP-020 (MGAT2-IN-1) is an orally active inhibitor of monoacylglycerol acyltransferase (MGAT2) with IC 50 of 7.8 and 2.4 nM for human and mouse MGAT2, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MGAT2-IN-1. CAS No. 1800025-30-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101857. |  |
| TP-021 | TP-021 (BCL6-IN-8c) is a potent and orally active B-cell lymphoma 6 (BCL6)-corepressor interaction inhibitor with an IC 50 of 0.10 μM in cell-free enzyme-linked immunosorbent assay [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BCL6-IN-8c. CAS No. 2130878-25-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119402. | |
| TP-024 | TP-024 (FTBMT) is a selective GPR52 agonist with an EC 50 of 75 nM [1]. TP-024 has antipsychotic and procognitive properties [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FTBMT. CAS No. 1358575-02-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101787. | |
| TP-040 | TP-040 (O-GlcNAcase-IN-1) is a potent and novel OGA inhibitor with an IC 50 value of 46 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: O-GlcNAcase-IN-1. CAS No. 2757254-99-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131979. | |
| TP0427736 | TP0427736 is a potent and selective inhibitor of ALK5 kinase activity with IC50 value of 2.72 nM. It was shown to inhibit Smad2/3 phosphorylation in A549 cells induced by TGF-β1 with IC50 value of 8.68 nM. Synonyms: TP 0427736; TP-0427736; 6-[5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-4-yl]-1,3-benzothiazole. CAS No. 864374-00-5. Molecular formula: C14H10N4S2. Mole weight: 298.4. |  |
| TP0427736 hydrochloride | TP0427736 hydrochloride is a potent inhibitor of ALK5 kinase activity with an IC 50 of 2.72 nM and this effect is 300-fold higher than the inhibitory effect on ALK3 (IC 50 =836 nM). TP0427736 hydrochloride also inhibits Smad2/3 phosphorylation in A549 cells induced by TGF-β1 with an IC 50 value of 8.68 nM. TP0427736 hydrochloride can be used for the research of androgenic alopecia (AGA) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2459963-17-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118528A. | |
| TP0463518 | TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases ( PHD s) inhibitor with a K i value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1 / PHD3 with IC 50 s of 18 and 63 nM as well as monkey PHD2 with an IC 50 value of 22 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1558021-37-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112144. | |
| TP-060 | Glucosylceramide synthase-IN-1 (T-036) a potent, brain-penetrant and orally active glucosylceramide synthase (GCS) inhibitor with IC 50 s of 31 nM and 51 nM for human GCS and mouse GCS, respectively. Glucosylceramide synthase-IN-1 can be used for Gaucher's disease research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glucosylceramide synthase-IN-1. CAS No. 2601393-20-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144266. | |
| TP 064 | TP 064 is a potent and selective PRMT4 inhibitor with >100-fold selectivity over other histone methyltransferases and non-epigenetic targets. TP 064 inhibits methylation of H3 (1-25) and MED12 in cellular assays (IC50 values are <10 and 43 nM, respectively). Synonyms: TP-064; TP064; N-Methyl-N-((2-(1-(2-(methylamino)ethyl)piperidin-4-yl)pyridin-4-yl)methyl)-3-phenoxybenzamide. Grades: ≥98% by HPLC. CAS No. 2080306-20-1. Molecular formula: C28H34N4O2. Mole weight: 458.6. | |
| TP-064 | TP-064 is a potent and selective proteinarginine methyltransferase 4 (PRMT4; CARM1) inhibitor ( IC 50 <10 nM). TP-064 inhibits dimethylation of BAF155 ( IC 50 of 340 nM) and MED12 ( IC 50 of 43 nM). TP-064 is inactive against the other family members except for PRMT6 (IC 50 of 1.3 μM). TP-064 has anticancer activities [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2080306-20-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-114965. | |
| TP-064 TFA salt | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| TP-0903 | TP-0903 is a potent anti-cancer agent targeting the AXL receptor tyrosine kinase that has demonstrated profound activity in several cell-based and animal models of cancer. Uses: For research use only. Synonyms: TP-0903; TP 0903; TP0903. Grades: >98%. CAS No. 1341200-45-0. Molecular formula: C24H30ClN7O2S. Mole weight: 516.06. | |
| TP-10 | TP-10 is a PDE10A inhibitor with IC50 of 0.8 nM. It has extremely potent PDE10A inhibitory activity and high selectivity against other PDEs. It is active in the mouse behavioral model for positive symptoms. It demonstrats good in vitro and in vivo activity. Synonyms: TP-10; TP 10; TP10; 2-{4-[4-Pyridin-4-yl-1-(2,2,2-trifluoro-ethyl)-1H-pyrazol-3-yl]-phenoxymethyl}-quinoline;Substituted pyrazole, 13;2-[[4-[4-pyridin-4-yl-1-(2,2,2-trifluoroethyl)pyrazol-3-yl]phenoxy]methyl]quinoline. Grades: >98%. CAS No. 898563-00-3. Molecular formula: C26H19F3N4O. Mole weight: 460.45. | |
| TP-110 | TP-110 is a new proteasome inhibitor, which shows potent growth inhibition in various tumor cell lines. Treatment with TP-110 for 24 h in vitro induced apoptosis in multiple myeloma cell line RPMI8226. TP-110 reduced the intrinsic inhibitor of apoptosis proteins (IAPs), cIAP-1 and XIAP, that suppress executioner caspases. Synonyms: TP110; TP 110; Tyropeptin A 7. Grades: 98%. CAS No. 688737-95-3. Molecular formula: C37H41N3O6. Mole weight: 623.75. | |
| TP-1287 | TP-1287, a prodrug of Alvocidib (HY-10005), is an orally active CDK9 inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2044686-42-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153260. | |
| TP-238 hydrochloride | TP-238 hydrochloride is a potent and selective dual CECR2/BPTF probe with IC 50 values of 30 nM and 350 nM, respectively. TP-238 hydrochloride also inhibits BRD9 with a pIC 50 of 5.9 and is less active against other 338 kinases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2415263-05-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114205A. | |
| TP2(Nic) | TP2(Nic): TP2(Nic) is a potent small-molecule antagonist that targets nicotinic acetylcholine receptors. with specific binding affinity, TP2(Nic) effectively inhibits the interaction between nicotine and these receptors, thereby used for studying nicotine addiction and related disorders. Synonyms: Nicotinamide thymine dinucleotide, Sodium salt. Grades: ≥ 95 % by HPLC. Molecular formula: C21H28N4O15P2(free acid). Mole weight: 638.41 (free acid). | |
| TP3 | TP3 is an antimicrobial peptide isolated from Oreochromis niloticus. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Phe-Ile-His-His-Ile-Ile-Gly-Gly-Leu-Phe-Ser-Val-Gly-Lys-His-Ile-His-Ser-Leu-Ile-His-Gly-His. Grades: >97%. | |
| Tp3654 | Tp3654 is an inhibitor of Pim-1 and Pim-3 that has the potential to treat prostate cancer, acute myeloid leukemia, multiple sclerosis and psoriasis. Uses: Tp3654 is an inhibitor of pim-1 and pim-3. Synonyms: TP-3654; TP3654; TP 3654; SCHEMBL102560; CS-6293; HY-101126; CS 6293; HY 101126; CS6293; HY101126; 2-[4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexyl]propan-2-ol. Grades: ≥98%. CAS No. 1361951-15-6. Molecular formula: C22H25F3N4O. Mole weight: 418.464. | |
| TP-3654 | TP-3654 is a second-generation Pim kinase inhibitor with K i values of 5 and 42 nM for Pim-1 and Pim-3, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1361951-15-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101126. | |
| TP3PO | TP3PO. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3,5-Tri(diphenylphosphoryl-phen-3-yl)benzene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1311378-95-6. Molecular formula: C60H45O3P3. Mole weight: 906.92 g/mol. Product ID: ACM1311378956-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: TPPOTU. |  |
| TP4 | TP4 is an antimicrobial peptide isolated from Oreochromis niloticus. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Phe-Ile-His-His-Ile-Ile-Gly-Gly-Leu-Phe-Ser-Ala-Gly-Lys-Ala-Ile-His-Arg-Leu-Ile-Arg-Arg-Arg-Arg-Arg. Grades: >97%. | |
| TP-472 | TP-472 is an inhibitor of bromodomain BRD9 and BRD7 bromodomain with Kd values of 33 and 340 nM, respectively. Synonyms: 3-(6-Acetylpyrrolo[1,2-a]pyrimidin-8-yl)-N-cyclopropyl-4-methylbenzamide. Grades: ≥98%. CAS No. 2079895-62-6. Molecular formula: C20H19N3O2. Mole weight: 333.4. | |
| TP-472 | TP-472 is a selective BRD9/7 inhibitor, with Kds of 33 nM and 340 nM for BRD9 and BRD7, respectively. TP-472 exhibits >30-fold selectivity for BRD9 over other bromodomain family members except BRD7[1][2]. TP-472 induces apoptosis of melanoma cells[3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2079895-62-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-100517. | |
| TP-472 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| TP 472N | TP 472N is a negative control for TP 472. TP 472N is inactive against other bromodomains (>20 μM against BRD9). Synonyms: TP 472N; TP472N; TP-472N; 1- (8- (2- (Cyclopropylmethoxy) phenyl) pyrrolo[1, 2-a]pyrimidin-6-yl) ethanone. Grades: ≥98% by HPLC. CAS No. 2080306-24-5. Molecular formula: C19H18N2O2. Mole weight: 306.36. | |
| TP-472N | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| TP508 | TP508, also known as Chrysalin (OrthoLogic, Tempe, Arizona), is a 23 amino acid synthetic peptide representing residues 508-530 of human prothrombin. TP508 is a regenerative peptide drug representing a natural part of human thrombin that is released upon tissue injury to initiate a healing cascade. TP508 has demonstrated safety and potential efficacy in non-clinical and in human clinical tissue repair trials. Synonyms: TP508; TP 508; TP-508. Molecular formula: C97H146N28O36S. Mole weight: 2312.44. | |
| TP-5801 | TP-5801 is an orally active TNK1 ( non-receptor tyrosine kinase ) inhibitor ( IC 50 =1.40 nM), and shows anti-tumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2574474-81-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-147316. | |
| TP-808 | TP-808 is an intermediate used in tetracycline antibiotic synthesis with antimicrobial activity. TP-808 binds to the 30S ribosome subunit of the bacteria, preventing aminoacyl-trNA from entering the A site, thereby inhibiting the extension of the protein chain. TP-808 can be used in antibiotic drug development research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 852821-06-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13952. | |
| TPA | TPA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9,10-Bis[phenyl(m-tolyl)-amino]anthracene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 189263-81-8. Molecular formula: C40H32N2. Mole weight: 540.70 g/mol. Purity: 95%+. IUPACName: 9-N,10-N-bis(3-methylphenyl)-9-N,10-N-diphenylanthracene-9,10-diamine. Canonical SMILES: CC1=CC(=CC=C1)N(C2=CC=CC=C2)C3=C4C=CC=CC4=C(C5=CC=CC=C53)N(C6=CC=CC=C6)C7=CC=CC(=C7)C. Density: 1.194 ± 0.06 g/ml. Product ID: ACM189263818. Alfa Chemistry ISO 9001:2015 Certified. | |
| TPA023 | TPA023, also called as MK-0777, is a subtype-selective, mixed agonist-antagonist at GABAA receptor with anxiolytic and anticonvulsant effects. Synonyms: 7-tert-butyl-6-[(2-ethyl-1,2,4-triazol-3-yl)methoxy]-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazine; TPA023; TPA-023; TPA 023; MK0777; MK 0777; MK-0777; L830982; L-830982; L 830982. Grades: >98%. CAS No. 252977-51-8. Molecular formula: C20H22FN7O. Mole weight: 395.44. | |
| TPA-696 | TPA-696. Group: Polymersacrylic resins. |  |
| TPA-DCPP | TPA-DCPP. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7,10-Bis(4-(diphenylamino)phenyl)-2,3-dicyanopyrazino-phenanthrene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1803287-94-6. Molecular formula: C54H34N6. Mole weight: 766.89 g/mol. Product ID: ACM1803287946. Alfa Chemistry ISO 9001:2015 Certified. | |
| TPA_exp: DEFB103-like protein | TPA_exp: DEFB103-like protein is an antimicrobial peptide isolated from Papio anubis. It has anti-gram-positive bacteria, gram-negative bacteria, anti-fungal and anti-viral activities. Synonyms: Gln-Lys-Tyr-Tyr-Cys-Arg-Val-Arg-Gly-Gly-Arg-Cys-Ala-Val-Leu-Ser-Cys-Leu-Pro-Lys-Glu-Glu-Gln-Ile-Gly-Lys-Cys-Ser-Thr-Arg-Gly-Arg-Lys-Cys-Cys-Arg. | |
| TPA_exp: DEFB4-like protein | TPA_exp: DEFB4-like protein is an antimicrobial peptide isolated from Papio anubis. It has anti-gram-positive bacteria, gram-negative bacteria, anti-fungal and anti-viral activities. Synonyms: Ile-Arg-Asn-Pro-Val-Thr-Cys-Ile-Arg-Ser-Gly-Ala-Ile-Cys-Tyr-Pro-Arg-Ser-Cys-Pro-Gly-Ser-Tyr-Lys-Gln-Ile-Gly-Val-Cys-Gly-Val-Ser-Val-Ile-Lys-Cys-Cys-Lys-Lys-Pro. | |
| TPA_exp: EP2E protein | TPA_exp: EP2E protein is an antimicrobial peptide isolated from Sus scrofa. Synonyms: Arg-Asp-Val-Ile-Cys-Leu-Met-Gln-His-Gly-Thr-Cys-Arg-Leu-Phe-Phe-Cys-His-Ser-Gly-Glu-Lys-Lys-Ser-Glu-Ile-Cys-Ser-Asp-Pro-Trp-Asn-Arg-Cys-Cys. | |
| TPA: ovochymase precursor (314-332) | | |
| TPA-SBFF | TPA-SBFF. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N5,N5,N9,N9-Tetraphenylspiro[benzo[c]fluorene-7,9'-fluorene]-5,9-diamine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1262333-45-8. Molecular formula: C53H36N2. Mole weight: 700.87 g/mol. Product ID: ACM1262333458. Alfa Chemistry ISO 9001:2015 Certified. | |
| TPB3 | TPB3. Group: Organic light-emitting diode (oled) materials. CAS No. 349666-25-7. Product ID: 1-[3,5-di(pyren-1-yl)phenyl]pyrene. Molecular formula: 678.8g/mol. Mole weight: C54H30. C1=CC2=C3C (=C1)C=CC4=C (C=CC (=C43)C=C2)C5=CC (=CC (=C5)C6=C7C=CC8=CC=CC9=C8C7=C (C=C9)C=C6)C1=C2C=CC3=CC=CC4=C3C2=C (C=C4)C=C1. InChI= 1S / C54H30 / c1-4-31-10-13-37-16-22-43 (46-25-19-34 (7-1) 49 (31) 52 (37) 46) 40-28-41 (44-23-17-38-14-11-32-5-2-8-35-20-26- 47 (44) 53 (38) 50 (32) 35) 30-42 (29-40) 45-24-18-39-15-12-33-6-3-9-36-21-27-4 8 (45) 54 (39) 51 (33) 36 / h1-30H. HDMYKJVSQIHZLM-UHFFFAOYSA-N. | |
| TPBA | TPBA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 9,9',10,10'-Tetraphenyl-2,2'-bianthracene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 172285-72-2. Molecular formula: C52H34. Mole weight: 658.83 g/mol. Purity: 95%+. IUPACName: 2-(9,10-diphenylanthracen-2-yl)-9,10-diphenylanthracene. Canonical SMILES: C1=CC=C(C=C1)C2=C3C=CC(=CC3=C(C4=CC=CC=C42)C5=CC=CC=C5)C6=CC7=C(C8=CC=CC=C8C(=C7C=C6)C9=CC=CC=C9)C1=CC=CC=C1. Product ID: ACM172285722. Alfa Chemistry ISO 9001:2015 Certified. Categories: TPB AFK. | |
| TPBi | TPBi. Uses: Used in oled's devices as electron transport and exciton blocking materials. Group: Organic light-emitting diode (oled) materials. Alternative Names: 2,2',2"-(1,3,5-Benzinetriyl)-tris(1-phenyl-1-H-benzimidazole). CAS No. 192198-85-9. Pack Sizes: 500 mg in poly bottle. Product ID: 2-[3,5-bis(1-phenylbenzimidazol-2-yl)phenyl]-1-phenylbenzimidazole. Molecular formula: 654.76. Mole weight: C45H30N6. C1 (C2=NC (C=CC=C3)=C3N2C4=CC=CC=C4)=CC (C5=NC (C=CC=C6)=C6N5C7=CC=CC=C7)=CC (C8=NC (C=CC=C9)=C9N8C%10=CC=CC=C%10)=C1. InChI=1S/C45H30N6/c1-4-16-34 (17-5-1)49-40-25-13-10-22-37 (40)46-43 (49)31-28-32 (44-47-38-23-11-14-26-41 (38)50 (44)35-18-6-2-7-19-35)30-33 (29-31)45-48-39-24-12-15-27-42 (39)51 (45)36-20-8-3-9-21-36/h1-30H, GEQBRULPNIVQPP-UHFFFAOYSA-N. GEQBRULPNIVQPP-UHFFFAOYSA-N. 95%+. | |
| TPBi; 1,3,5-Tris(1-phenyl-1H-benzimidazol-2-yl)benzene, >99%(HPLC), Sublimed | TPBi; 1,3,5-Tris(1-phenyl-1H-benzimidazol-2-yl)benzene, >99%(HPLC), Sublimed. Group: Substrates and electrode materials. CAS No. 192198-85-9. Product ID: 2-[3,5-bis(1-phenylbenzimidazol-2-yl)phenyl]-1-phenylbenzimidazole. Molecular formula: 654.8g/mol. Mole weight: C45H30N6. C1=CC=C (C=C1) N2C3=CC=CC=C3N=C2C4=CC (=CC (=C4) C5=NC6=CC=CC=C6N5C7=CC=CC=C7) C8=NC9=CC=CC=C9N8C1=CC=CC=C1. InChI=1S/C45H30N6/c1-4-16-34 (17-5-1)49-40-25-13-10-22-37 (40)46-43 (49)31-28-32 (44-47-38-23-11-14-26-41 (38)50 (44)35-18-6-2-7-19-35)30-33 (29-31)45-48-39-24-12-15-27-42 (39)51 (45)36-20-8-3-9-21-36/h1-30H. GEQBRULPNIVQPP-UHFFFAOYSA-N. | |
| TPBM | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| TPBM | TPBM is a potent estrogen receptor α (ERα) inhibitor with an IC 50 value of 9 μM for 17β-estradiol (E2)-ER&alpha. TPBM reduces E2·ERα recruitment to an endogenous estrogen-responsive gene. TPBM inhibits E2-dependent growth of ERα-positive cancer cells (IC 50 =5 μM). TPBM is not toxic to cells and does not affect estrogen-independent cell growth [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 6466-43-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131404. | |
| TPC-144 | TPC-144 is a novel and selective LSD1 inhibitor potentially used for the treatment of acute myeloid leukemia (AML) and small cell lung cancer (SCLC). TPC-144 reversibly inhibited LSD1 in a histone peptide-competitive manner not forming a covalent adduct with FAD. Uses: The potential treatment of aml and sclc. Synonyms: TPC-144; TPC144; TPC 144; 5'-((1R,3r,5S)-3-amino-8-azabicyclo[3.2.1]octane-8-carbonyl)-2'',3-difluoro-4''-(2-hydroxy-2-methylpropyl)-[1,1':2',1''-terphenyl]-4-carbonitrile. CAS No. 2098621-17-9. Molecular formula: C31H31F2N3O2. Mole weight: 515.6048. | |
| TPC2-A1-N | TPC2-A1-N is a powerful and Ca2+-permeable agonist of two pore channel 2 (TPC2), which plays its role by mimicking the physiological actions of NAADP. TPC2-A1-P reproducibly evokes significant Ca2+ responses from TPC2 (EC50=7.8 ?M), and the effect can be blocked by several TPC blockers. TPC2-A1-N can be used to probe different functions of TPC2 channels in intact cells[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 136186-07-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131614. | |
| TPC2-A1-P | TPC2-A1-P is a powerful and membrane permeable agonist of two pore channel 2 (TPC2) with an EC50 of 10.5 ?M. TPC2-A1-P plays its role by mimicking the physiological actions of PI(3,5)P2. TPC2-A1-P also shows higher potency to induce Na2+ mobilisation from TPC2 than TPC-A1-N (HY-131614). TPC2-A1-P can be used to probe different functions of TPC2 channels in intact cells[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2804595-86-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131615. | |
| TPCA-1 | TPCA-1 is a potent and selective inhibitor of IKK-2 with IC50 of 17.9 nM. TPCA-1 is an effective inhibitor of STAT3 phosphorylation, DNA binding, and transactivation. Uses: Scientific research. Group: Signaling pathways. CAS No. 507475-17-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10074. | |
| TPCA-1 | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| TPCA-1 | TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM and 0.40 μM for IKK-1 and IKK-2 respectively. It blocks NF-κB pathway and STAT3 activity. Synonyms: TPCA1; TPCA 1; 5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide; IKK-2 Inhibitor IV. Grades: >98%. CAS No. 507475-17-4. Molecular formula: C12H10FN3O2S. Mole weight: 279.29. | |
| TPCA-1 | TPCA-1. Group: Biochemicals. Grades: Purified. CAS No. 507475-17-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| TPCK-treated Trypsin | TPCK-treated Trypsin is a trypsin whose activity is inhibited by tosyl phenylalanyl chloromethyl ketone. TPCK-treated Trypsin reduces autolysis and nonspecific proteolysis during experiments, exhibits stability in storage and handling. TPCK-treated trypsin can be used in proteomics research[1]. TPCK-treated Trypsin renders the virus hemagglutinin active, which allows multicycle replication of the virus. TPCK-treated Trypsin can be used for the study of influenza virus[2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 9002-7-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129047C. | |
| TPCS2a | TPCS2a, also know as, tetraphenyl chlorin disulfonate, is a meso-tetraphenylchlorin substituted by two adjacent sulfonated groups with potential photosensitizing activity. Upon administration, tetraphenyl chlorin disulfonate incorporates into the cell endosome and lysosome membranes. Subsequently, cytotoxic agents are administered and accumulate in endosomal and lysosomal compartments; upon local activation by light, tetraphenyl chlorin disulfonate produces reactive oxygen species (ROS), such as singlet oxygen, damaging endo/lysosomal membranes and accumulated cytotoxic agents are released into the tumor cell cytosol. This photochemical internalization (PCI) method can enhance the efficacy and selectivity of cytotoxic agents. Synonyms: Benzenesulfonic acid, 4,4'-(7,8-dihydro-15,20-diphenyl-21H,23H-porphine-5,10-diyl)bis-; 4,4'-(7,8-Dihydro-15,20-diphenyl-21H,23H-porphine-5,10-diyl)bis[benzenesulfonic acid]; Amphinex; Di(monoethanolammonium) meso-tetraphenyl chlorin disulfonate; Fimaporfin A; Tetraphenyl chlorin disulfonate. Grades: ≥95%. CAS No. 501083-97-2. Molecular formula: C44H32N4O6S2. Mole weight: 776.88. | |
| TPDI-Hex | Band gap: 2.1 eV. Group: Organic field effect transistor (ofet) materials organic solar cell (opv) materials. Alternative Names: 2, 2', 8, 8'-Tetrakis(1-ethylpropyl)-5, 5'-dihexyl-[11, 11'-Bi-1H-pyrrolo[2', 3', 4', 5':4, 5]phenanthro[2, 1, 10-def:7, 8, 9-d'e'f']diisoquinoline]-1, 1', 3, 3', 7, 7', 9, 9'(2H, 2'H, 5H, 5'H, 8H, 8'H)-octone. CAS No. 2011757-24-5. | |
| TPD-OSU [O-Succinimidyl-1, 3-dimethylpropyl eneuronium tetrafluoroborate] | TPD-OSU [O-Succinimidyl-1, 3-dimethylpropyl eneuronium tetrafluoroborate]. Group: Biochemicals. Grades: Highly Purified. CAS No. 443305-34-8. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
| TPE-MI | TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum [1][2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Tetraphenylethene maleimide. CAS No. 1245606-71-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143218. | |
| TPEN | TPEN is a heavy metal chelator that acts as an intracellular chelator of proteomic Zn2+. TPEN decreases intracellular zinc levels, and induces apoptosis in HeLa and cultured human retinal pigment epithelium (RPE) cells. Synonyms: TPEN; TPEDA. N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine; N1,N1,N2,N2-Tetrakis(pyridin-2-ylmethyl)ethane-1,2-diamine. Grades: ≥98% by HPLC. CAS No. 16858-02-9. Molecular formula: C26H28N6. Mole weight: 424.54. | |
| TPEN | TPEN. CAS No. 16858-02-9. Product ID: PE-0346. Molecular formula: C26H28N6. Category: Hydrotropy Agent Excipients. Product Keywords: Pharmaceutical Excipients; Hydrotropy Agent Excipients; TPEN; PE-0346; 16858-02-9; C26H28N6; 16858-02-9. Purity: 0.9902. Solubility: DMSO. |  |
| TPEN | TPEN. Group: Biochemicals. Grades: Purified. CAS No. 16858-02-9. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| TPEN | TPEN (TPEDA) is a specific cell-permeable heavy metal chelator. TPEN has a higher affinity for Zn2+, but a lower affinity for Mg2+ and Ca2+. TPEN induces DNA damage and increases intracellular ROS production. TPEN also inhibits cell proliferation and induces apoptosis[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TPEDA. CAS No. 16858-02-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-100202. | |
| T-Peptide | T-peptide, a highly neurotoxic cell-permeable analog of PHF6, can be used in the study of human immunodeficiency virus (HIV) infection. T-peptide can induce Tau peptide aggregation, prevent cellular immunosuppression, improve the survival rate of sepsis mice, and inhibit the growth of residual tumor cells after surgical resection. Synonyms: PHF6-R9; L-Argininamide, N-acetyl-D-valyl-D-glutaminyl-D-isoleucyl-D-valyl-D-tyrosyl-D-lysyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-; Ac-D-Val-D-Gln-D-Ile-D-Val-D-Tyr-D-Lys-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-NH2; N-acetyl-D-valyl-D-glutaminyl-D-isoleucyl-D-valyl-D-tyrosyl-D-lysyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-argininamide. Grades: ≥95%. CAS No. 2022956-62-1. Molecular formula: C92H171N45O18. Mole weight: 2195.66. | |
| TPh A | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| TPh A (Triphenyl Compound A, 4-Methyl-N-(methyl(4-(phenylmethoxy) phenyl)-lambda4-sulfanylidene-benzene-sulfonamide, S-S-methyl-N-(p-tolylsulfonyl)-sulfilimine) | Nuclear protein pirin inhibitor. Inhibits the interaction between Bcl3 oncoprotein and the nuclear protein pirin. Melanoma cell migration inhibitor. Group: Biochemicals. Alternative Names: Triphenyl Compound A, 4-Methyl-N-(methyl(4-(phenylmethoxy) phenyl)-lambda4-sulfanylidene-benzene-sulfonamide, S--S-methyl-N-(p-tolylsulfonyl)-sulfilimine. Grades: Highly Purified. CAS No. 21306-65-0. Pack Sizes: 1mg, 5mg. Molecular Formula: C21H21NO3S2. US Biological Life Sciences. | Worldwide |
| TPH Banded - Clay Soil | certified reference material, pkg of 100 g. Group: Certified reference materials (crms). | |
| TPH - Clay Loam 1 | certified reference material, pkg of 100 g. Group: Certified reference materials (crms). | |
| TPH in Soil | certified reference material. Group: Certified reference materials (crms). | |
| TPH in Soil - Low | certified reference material. Group: Certified reference materials (crms). | |
| TPH in Water | certified reference material. Group: Certified reference materials (crms). | |
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