A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
certified reference material, pkg of 100 g. Group: Certified reference materials (crms).
TPH - Loamy Sand 2
certified reference material, pkg of 100 g. Group: Certified reference materials (crms).
TPH - Loamy Soil
pkg of 100 g. Group: Certified reference materials (crms).
TPH - Sand 1
certified reference material, pkg of 100 g. Group: Certified reference materials (crms).
TPH - Sandy Clay Loam 1
certified reference material, pkg of 100 g. Group: Certified reference materials (crms).
TPH - Sandy Loam 1
certified reference material, pkg of 100 g. Group: Certified reference materials (crms).
TPH - Sandy Loam 2
certified reference material, pkg of 100 g. Group: Certified reference materials (crms).
TPH - Sandy Loam 4
pkg of 100 g. Group: Certified reference materials (crms).
TPH - Sea Sediment 1
pkg of 100 g. Group: Certified reference materials (crms).
TPI-1
TPI-1 selectively increased SHP-1 phospho-substrates (pLck-pY394, pZap70, and pSlp76) in Jurkat T cells but had little effects on pERK1/2 or pLck-pY505 regulated by phosphatases SHP-2 or CD45, respectively. Synonyms: 2-(2,5-dichlorophenyl)cyclohexa-2,5-diene-1,4-dione; 2-(2,5-dichlorophenyl)cyclohexa-2,5-diene-1,4-dione; 2-(2',5'-dichlorophenyl)-1,4-benzoquinone; CBMicro_042121; TPI-1; TPI 1; TPI1; Tyrosine Phosphatase Inhibitor 1. CAS No. 79756-69-7. Molecular formula: C12H6Cl2O2. Mole weight: 253.08.
TPI-287
TPI-287, a blood-brain barrier-permeable microtubule stabilizer, can significantly reduce metastatic colonization of breast cancer in the brain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 849213-15-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-126899.
TPI-287
TPI 287 is a synthetic, third generation taxane with potential antineoplastic activity. TPI 287 binds to tubulin and stabilizes microtubules, resulting in inhibition of microtubule assembly/disassembly dynamics, cell cycle arrest at the G2/M phase, and apoptosis. Synonyms: TPI-287; TPI287; ARC-100; ARC 100; ARC100; TPI 287. CAS No. 849213-15-6. Molecular formula: C46H63NO15. Mole weight: 870.00.
TPI HLA-DR1
A peptide used in the research on the treatment of melanoma.
Tpl2 Kinase Inhibitor - CAS 871307-18-5
The Tpl2 Kinase Inhibitor, also referenced under CAS 871307-18-5, controls the biological activity of Tpl2 Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy.
t-plasminogen activator
A peptidase of family S1 (trypsin family) from a wide variety of mammalian tissues, especially endothelial cells. Secreted as a single chain precursor which is cleaved to a two-chain form by plasmin. Activity is considerably enhanced by fibrin. Formerly included in EC 3.4.21.31 and EC 3.4.99.26. Group: Enzymes. Synonyms: tissue plasminogen activator; plasminogen activator, tissue-type; tissue-type plasminogen activator; tPA; t-PA. Enzyme Commission Number: EC 3.4.21.68. CAS No. 139639-23-9. tPA. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4159; t-plasminogen activator; EC 3.4.21.68; 139639-23-9; tissue plasminogen activator; plasminogen activator, tissue-type; tissue-type plasminogen activator; tPA; t-PA. Cat No: EXWM-4159.
TPMPA
TPMPA. Group: Biochemicals. Grades: Purified. CAS No. 182485-36-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TPMPA
TPMPA, a hybrid of isoguvacine and 3-APMPA, is the first selective antagonist for a GABA C receptor ( K B = 2.1 μM), but not to interact with GABA A ( K B = 320 μM) or GABA B receptors ( EC 50 = 500 μM). TPMPA has the potential for the research of suppressing orientation selectivity in ganglion cells [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 182485-36-5. Pack Sizes: 10 mg. Product ID: HY-101359.
TPMPA
TPMPA is a selective and competitive GABAA-ρ antagonist with 8-fold selectivity for human recombinant ρ1 receptors over ρ2 receptors. TPMPA exhibits minimal effects on GABAA and GABAB receptors (Kb = 2.1 μM (antagonist), 320 μM (antagonist) and EC50 ~ 500 μM (weak agonist) for GABAA-ρ, GABAA and GABAB receptors, respectively). Synonyms: (1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid; methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid. Grades: ≥98% by HPLC. CAS No. 182485-36-5. Molecular formula: C6H12NO2P. Mole weight: 161.14.
TPM-TAZ
TPM-TAZ. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,4,6-Tris(3-(pyrimidin-5-yl)phenyl)-1,3,5-triazine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1874199-82-2. Molecular formula: C33H21N9. Mole weight: 543.58 g/mol. Product ID: ACM1874199822. Alfa Chemistry ISO 9001:2015 Certified. Categories: TP Mazembe.
TPO from mouse
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
TPO human
Animal-component free, recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
TPO mouse
Animal-component free, recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy.
TPOP146
TPOP146 is a potent and selective CBP/P300 benzoxazepine bromodomain inhibitor with Kd values of 134 nM and 5.02 μM for CBP and BRD4. TPOP146 targets the CBP bromodomain in the nucleus and is capable of competing with acetyl-lysine mediated interactions of the CBP bromodomain in cellular environments. Synonyms: TPOP146; TPOP-146; TPOP 146. 7-(3,5-dimethoxyphenyl)-N-[(3S)-1-methylpiperidin-3-yl]-4-propanoyl-3,5-dihydro-2H-1,4-benzoxazepine-9-carboxamide. CAS No. 2018300-62-2. Molecular formula: C27H35N3O5. Mole weight: 481.58.
Ultra-high sensitive spectrophotometric reagent for Cu. Group: Uv/visible (uv/vis) spectroscopy. Alternative Names: Tetraphenylporphyrin.
TPP-1
TPP-1 is a potent inhibitor of the PD-1/PD-L1 interaction. TPP-1 binds specifically to PD-L1 with a high affinity ( K D =95 nM). TPP-1 inhibits human tumor growth in vivo via reactivating T-cell function [1]. Uses: Scientific research. Group: Peptides. CAS No. 2426685-25-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P3139.
TPP3
TPP3 is an antimicrobial peptide isolated from Lycopersicon esculentum. It has activity against fungi. Synonyms: Gln-Ile-Cys-Lys-Ala-Pro-Ser-Gln-Thr-Phe-Pro-Gly-Leu-Cys-Phe-Met-Asp-Ser-Ser-Cys-Arg-Lys-Tyr-Cys-Ile-Lys-Glu-Lys-Phe-Thr-Gly-Gly-His-Cys-Ser-Lys-Leu-Gln-Arg-Lys-Cys-Leu-Cys-Thr-Lys-Pro-Cys.
TPPS
Ultra-high sensitive spectrophotometric reagent for transition metals. Group: Uv/visible (uv/vis) spectroscopy. Alternative Names: 5,10,15,20-Tetrakis(4-sulfophenyl)porphyrin; Tetraphenylporphyrin Tetrasulfonic Acid.
TPPS can be used as a non-cytotoxic probe for detecting tumor location [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 35218-75-8. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-W075353.
TTPU is a soluble epoxide hydrolase inhibitor (sEHI) (IC50 = 37, 2.8 nM and 3.7 nM for monkey, mouse and human sEH, respectively) with anti-inflammatory, anti-hypertensive, neuroprotective, and cardioprotective effects. Synonyms: 1-(1-propanoylpiperidin-4-yl)-3-[4-(trifluoromethoxy)phenyl]urea. CAS No. 1222780-33-7. Molecular formula: C16H20F3N3O3. Mole weight: 359.34.
TpPyPB
TpPyPB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3,5-Tri(p-pyrid-3-yl-phenyl)benzene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 921205-02-9. Molecular formula: C39H27N3. Mole weight: 537.65 g/mol. Product ID: ACM921205029. Alfa Chemistry ISO 9001:2015 Certified.
TPT1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N4,N4'-(Biphenyl-4,4'-diyl)bis(N4,N4',N4'-triphenylbiphenyl-4,4'-diamine). Product Category: Organic Light Emitting Diode (OLED). CAS No. 167218-46-4. Molecular formula: C72H54N4. Mole weight: 975.23 g/mol. Product ID: ACM167218464. Alfa Chemistry ISO 9001:2015 Certified.
TPT-172
TPT-172, also known as R33 (described in Mecozzi et al' s paper), is a thiophene thiourea derivative with molecule weight 172 in free base form. There is no formal name yet, we temporally call this molecule as TPT-172. Uses: For research used only. Synonyms: TPT-172; TPT 172; TPT172; thiophene thiourea derivative. R33; R 33; R-33. Grades: 98%. CAS No. 32415-42-2. Molecular formula: C6H9ClN2S2. Mole weight: 208.72.
TPT-260
TPT-260 is a thiophene thiourea derivative with molecule weight 260.00 in free base form. Synonyms: TPU-260; TPU 260; TPU260. Grades: >98%. CAS No. 769856-81-7. Molecular formula: C8H12N4S3. Mole weight: 260.4.
TPT-260 2HCl
TPT-260 2HCl is a thiophene thiourea derivative that acts as a chaperone to stabilize the retromer complex against thermal denaturation. Synonyms: TPT-260 Dihydrochloride; TPT-260 (Dihydrochloride); Thiophene-2,5-diylbis(methylene) dicarbamimidothioate dihydrochloride; [5- (Carbamimidoylsulfanylmethyl) thiophen-2-yl]methyl carbamimidothioate dihydrochloride. Grades: 98%. CAS No. 2076-91-7. Molecular formula: C8H14Cl2N4S3. Mole weight: 333.32.
TPT-260 Dihydrochloride
TPT-260 Dihydrochloride (NSC55712) is a thiourea derivative. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NSC55712; TPU-260 Dihydrochloride. CAS No. 2076-91-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13769A.
TPTDP
TPTDP. Group: Biochemicals. Alternative Names: (6-Chlorobenzotri azol-1-yloxy) tri pyrrolidinophosphonium hexafluorophosphate; PyClock. Grades: Highly Purified. CAS No. 893413-42-8. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C18H27ClF6N6OP2. US Biological Life Sciences.
Tpt-ttf. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TPT-TTF, AGN-PC-00NAB4, Tetrakis(amylthio)tetrathiafulvalene, Tetrakis(pentylthio)tetrathiafulvalene, T1205, 2-[4,5-bis(pentylsulfanyl)-1,3-dithiol-2-ylidene]-4,5-bis(pentylsulfanyl)-1,3-dithiole, 106920-29-0. Product Category: Heterocyclic Organic Compound. CAS No. 106920-29-0. Molecular formula: C26H44S8. Mole weight: 613.15. Purity: 0.96. IUPACName: 2-[4,5-bis(pentylsulfanyl)-1,3-dithiol-2-ylidene]-4,5-bis(pentylsulfanyl)-1,3-dithiole. Density: 1.211g/cm³. Product ID: ACM106920290. Alfa Chemistry ISO 9001:2015 Certified.
TPTU
TPTU. Group: Biochemicals. Alternative Names: O-(2-Oxo-1(2H)pyridyl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; O-(1,2-Dihydro-2-oxo-1-pyridyl)-N,N,N'-N'-tetramethyluronium tetrafluoroborate. Grades: Highly Purified. CAS No. 125700-71-2. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C10H16BF4N3O2. US Biological Life Sciences.
Worldwide
TPTU
Applied in large scale applications for the synthesis of Pharmaceuticals, in particular in situations where sensitive functionality is present on the coupling partners, and as a consequence, mild reaction conditions are required. Uses: Peptide Synthesis. Group: Coupling Reagents. Alternative Names: O-(2-Oxo-1(2H)pyridyl)-N,N,N?,N?-tetramethyluronium tetrafluoroborate. CAS No. 125700-71-2.
Luxembourg Bio Technologies
TPU-0031-A
TPU-0031-A is an antibiotic of the novobiocin group produced by Streptomyces sp. TP-A0556. It shows antibiotic activity against Gram-positive and -negative bacteria. Molecular formula: C30H34N2O11. Mole weight: 598.6.
TPU-0031-B
TPU-0031-B is an antibiotic of the novobiocin group produced by Streptomyces sp. TP-A0556. It shows antibiotic activity against Gram-positive and -negative bacteria. Molecular formula: C30H34N2O11. Mole weight: 598.6.
TPU-0037A
TPU-0037A is a neurogenesis agent isolated from Streptomyces. Synonyms: 30-Demethyllydicamycin. Grades: >95% by HPLC. CAS No. 485815-59-6. Molecular formula: C46H72N4O10. Mole weight: 841.08.
TPU-0037B
TPU-0037B is a lydicamycin congener with anti-MRSA activity isolated from a culture broth of an actinomycete strain. It is closely related to BN 4515N which was isolated from a strain of microtetraspora as a neuritogenic agent. Synonyms: TPU-0037 B. Molecular formula: C47H72N4O9. Mole weight: 837.09.
TPU-0037C
A close structural analogue of lydicamycin produced by the marine actinomycete Streptomyces platensis. It has antibacterial activity against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). It is closely related to BU-4514N which is isolated from a strain of microtetraspora as a neuritogenic agent. Synonyms: Antibiotic TPU-0037C; 8-Dehydroxy-30-demethyllydicamycin; (+)?-2-[21-[1-[(2,?5-Dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl)?carbonyl]?-1,?2,?4a,?5,?6,?7,?8,?8a-octahydro-5-hydroxy-1,?3-dimethyl-2-naphthalenyl]?-2,?6,?10,?14,?18-pentahydroxy-11,?17,?19-trimethyl-4,?8,?12,?16-heneicosatetraen-1-yl]?-1-pyrrolidinecarboximi?damide. Grades: >95% by HPLC. CAS No. 485815-61-0. Molecular formula: C46H72N4O9. Mole weight: 825.09.
TPU-0037D
TPU-0037D is a lydicamycin congener with anti-MRSA activity isolated from a culture broth of an actinomycete strain. It is closely related to BN 4515N which was isolated from a strain of microtetraspora as a neuritogenic agent. Synonyms: TPU-0037 D. Molecular formula: C47H74N4O9. Mole weight: 839.11.
TPX-0131
TPX-0131 is a Potent CNS-penetrant, Next-generation Inhibitor of Wild-type ALK and ALK-resistant Mutations. In cellular assays, TPX-0131 was more potent than all five approved ALK inhibitors against WT ALK and many types of ALK resistance mutations, e.g., G1202R, L1196M, and compound mutations. In biochemical assays, TPX-0131 potently inhibited (IC50 <10 nmol/L) WT ALK and 26 ALK mutants (single and compound mutations). TPX-0131, but not lorlatinib, caused complete tumor regression in ALK (G1202R) and ALK compound mutation-dependent xenograft models. Following repeat oral administration of TPX-0131 to rats, brain levels of TPX-0131 were approximately 66% of those observed in plasma. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TPX-0131; TPX 0131; TPX0131. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2648641-36-3. Molecular formula: C21H20F3N5O3. Mole weight: 447.42. Purity:>98%. IUPACName: (S,14aE,15aE)-13-(difluoromethyl)-35-fluoro-6,6-dimethyl-13,14-dihydro-12H-4-oxa-7-aza-1(4,6)-pyrazolo[1',5':1,2]pyrimido[5,4-b][1,4]oxazina-3(1,2)-benzenacyclooctaphan-8-one. Canonical SMILES: FC([C@H]1N2C3=NC4=C(C(NC(C)(COC5=CC=C(F)C=C5C2)C)=O)C=NN4C=C3OC1)F. Product ID: ACM2648641363. Alfa Chemistry ISO 9001:2015 Certified.
TPXZPO. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 10,10',10''-(4,4',4''-Phosphoryltris(benzene-4,1-diyl))tris(10H-phenoxazine). Product Category: Organic Light Emitting Diode (OLED). CAS No. 2001115-35-9. Molecular formula: C54H36N3O4P. Mole weight: 821.86 g/mol. Product ID: ACM2001115359. Alfa Chemistry ISO 9001:2015 Certified.
TPY-5628
TPY-5628, a pyrrole derivative, has been found to be commonly used in sorts of chemical areas like anticancer drugs as an significant intermediate. Synonyms: TPY-5628; TPY 5628; TPY5628. 5,5'-[(3,4-DIETHYL-1H-PYRROLE-2,5-DIYL)BIS(METHYLENE)]BIS[4-(3-HYDROXYPROPYL)-3-METHYL-1H-PYRROLE-2-CARBOXALDEHYDE]; AGN-PC-004ZVA; SCHEMBL4107546; CTK4C6172; DTXSID00459675. Grades: 98%. CAS No. 149365-62-8. Molecular formula: C28H39N3O4. Mole weight: 481.64.
TPyPA
TPyPA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tris[4-(pyrenyl)-phenyl]amine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 349669-77-8. Molecular formula: C66H39N. Mole weight: 846.02 g/mol. Product ID: ACM349669778-1. Alfa Chemistry ISO 9001:2015 Certified. Categories: Trypanosoma brucei.
TPyQB
TPyQB. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3,5-Tris(4-(pyridin-4-yl)quinolin-2-yl)benzene. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1350742-68-5. Molecular formula: C48H30N6. Mole weight: 690.79 g/mol. Product ID: ACM1350742685. Alfa Chemistry ISO 9001:2015 Certified.
TQ1
TQ1. Group: Organic field effect transistor (ofet) materials organic solar cell (opv) materials. CAS No. 565228-37-7.
TQS
TQS is a α7 nicotinic acetylcholine receptor ( nAChR ) positive allosteric modulator. TQS can be used for the research of neuroinflammatory pain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 353483-92-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107682.
TQS
TQS. Group: Biochemicals. Grades: Purified. CAS No. 353483-92-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
TQS
TQS is a type II positive allosteric modulator of α7 nACh receptors (pEC50 = 5.5) with no activity at α7 receptors at concentrations up to 0.1 mM. TQS potentiates agonist-evoked responses and reduces rate of desensitization of α7 nAChRs. Synonyms: 3a,4,5,9b-Tetrahydro-4-(1-naphthalenyl)-3H-cyclopentan[c]quinoline-8-sulfonamide. Grades: ≥98% by HPLC. CAS No. 353483-92-8. Molecular formula: C22H20N2O2S. Mole weight: 376.47.
TQTPA
TQTPA. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tris(4-(quinolin-8-yl)phenyl)amine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1142945-07-0. Molecular formula: C45H30N4. Mole weight: 626.75 g/mol. Product ID: ACM1142945070. Alfa Chemistry ISO 9001:2015 Certified. Categories: TTPAL.
TR-100 is a small molecule inhibitor of tumor-associated troponin ( Tpm ). TR-100 affects the interaction of Tpm3.1 with actin filaments by binding to the C-terminal of Tpm3.1 , thereby affecting the stability and function of the actin filaments. This mechanism of action allows TR-100 to specifically affect actin filaments in cancer cells without compromising heart muscle function. TR-100 can be used to study the role of Tpm3.1 in cancer cell proliferation and survival and the effects of Tpm3.1 on insulin-stimulated glucose uptake and insulin secretion [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1128165-86-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-124689.
TR-14035
TR14035 blocked the binding of human alpha(4)beta(7) to an (125)I-MAdCAM-Ig fusion protein with IC(50) values of 0.75 nM. TR14035 blocked binding of human alpha(4)beta(7)-expressing RPMI-8866 cells or murine mesenteric lymph node lymphocytes to MAdCAM-Ig with IC(50) values of 0.1 microM. TR14035 blocked adhesion to HEVs [ED(50) of 0.01-0.1 mpk i.v.]. TR-14035 was taken up by rat and human hepatocytes by an apparently single saturable mechanism with K(m) of 6.7 and 2.1 microM, respectively, and taurocholate and digoxin reduced this uptake. Synonyms: TR 14035; TR14035; MDK-1191; MDK1191; MDK 1191; SB683698; SB 683698; SB-683698; QJ-2620; TR-14035. Grades: >98%. CAS No. 232271-19-1. Molecular formula: C24H21Cl2NO5. Mole weight: 474.33.