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Urotensin II (114-124), human TFA, an 11-amino acid residue peptide, is an agonist for the orphan receptor GPR14 and a potent vasoconstrictor. Synonyms: L-Valine, L-α-glutamyl-L-threonyl-L-prolyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (5→10)-disulfide trifluoroacetate salt; Human UII trifluoroacetate salt; Human urotensin II trifluoroacetate salt; Urotensin II (human) trifluoroacetate salt; H-Glu-Thr-Pro-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH.TFA (Disulfide bridge: Cys5-Cys10); L-alpha-glutamyl-L-threonyl-L-prolyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-valine (5->10)-disulfide trifluoroacetic acid. Grade: ≥95%. Molecular formula: C66H86F3N13O20S2. Mole weight: 1502.59.
Urotensin II (Gillichthys mirabilis)
Urotensin II (Gillichthys mirabilis) is a peptide ligand that is the strongest known vasoconstrictor. Synonyms: Urotensin II, mouse; L-Valine, L-alanylglycyl-L-threonyl-L-alanyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (6→11)-disulfide; Gillichthys mirabilis urotensin II; Urotensin II (Gillichthys mirabilis reduced), cyclic (6→11)-disulfide; Urotensin II (goby); H-Ala-Gly-Thr-Ala-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH (Disulfide bridge: Cys6-Cys11); L-alanyl-glycyl-L-threonyl-L-alanyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-valine (6->11)-disulfide. Grade: ≥95%. CAS No. 9047-55-6. Molecular formula: C62H84N14O17S2. Mole weight: 1361.54.
Urotensin II (Gillichthys mirabilis) acetate
Urotensin II (Gillichthys mirabilis) acetate is a peptide ligand that is the strongest known vasoconstrictor. Synonyms: Urotensin II, mouse acetate; Gillichthys mirabilis urotensin II acetate; Urotensin II (Gillichthys mirabilis reduced), cyclic (6→11)-disulfide acetate; Urotensin II (goby) acetate; L-Valine, L-alanylglycyl-L-threonyl-L-alanyl-L-α-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (6→11)-disulfide acetate; H-Ala-Gly-Thr-Ala-Asp-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH.CH3CO2H (Disulfide bridge: Cys6-Cys11); L-alanyl-glycyl-L-threonyl-L-alanyl-L-alpha-aspartyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-valine (6->11)-disulfide acetate. Grade: ≥95%. Molecular formula: C64H88N14O19S2. Mole weight: 1421.61.
Urotensin ii(human)
Urotensin ii(human). Uses: Designed for use in research and industrial production. Additional or Alternative Names: UROTENSIN-II;UROTENSIN II (HUMAN) HYDROCHLORIDE;UROTENSIN II (HUMAN);ETPDCFWKYCV, HCL (DISULFIDE BRIDGE: 5-10);GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL;GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL HYDROCHLORIDE;H-GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS. Product Category: Heterocyclic Organic Compound. CAS No. 251293-28-4. Molecular formula: C64H87N13O18S2. Mole weight: 1390.58. Product ID: ACM251293284. Alfa Chemistry ISO 9001:2015 Certified.
Urotensin II, mouse
Urotensin II, mouse, a potent vasoconstrictor, is an endogenous ligand for the orphan GPR14 or SENR. Synonyms: L-Isoleucine, 5-oxo-L-prolyl-L-histidylglycyl-L-alanyl-L-alanyl-L-prolyl-L-α-glutamyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (8→13)-disulfide; H-Pyr-His-Gly-Ala-Ala-Pro-Glu-Cys-Phe-Trp-Lys-Tyr-Cys-Ile-OH (Disulfide bridge: Cys8-Cys13); L-pyroglutamyl-L-histidyl-glycyl-L-alanyl-L-alanyl-L-prolyl-L-alpha-glutamyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-isoleucine (8->13)-disulfide; Urotensin II (mouse). Grade: ≥95%. CAS No. 405137-01-1. Molecular formula: C76H100N18O19S2. Mole weight: 1633.85.
Urotensin II, mouse acetate
Urotensin II, mouse acetate, a potent vasoconstrictor, is an endogenous ligand for the orphan GPR14 or SENR. Synonyms: L-Isoleucine, 5-oxo-L-prolyl-L-histidylglycyl-L-alanyl-L-alanyl-L-prolyl-L-α-glutamyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (8→13)-disulfide, acetate; H-Pyr-His-Gly-Ala-Ala-Pro-Glu-Cys-Phe-Trp-Lys-Tyr-Cys-Ile-OH.CH3CO2H (Disulfide bridge: Cys8-Cys13); L-pyroglutamyl-L-histidyl-glycyl-L-alanyl-L-alanyl-L-prolyl-L-alpha-glutamyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-isoleucine (8->13)-disulfide acetate; Urotensin II (mouse) acetate. Grade: ≥95%. Molecular formula: C78H104N18O21S2. Mole weight: 1693.92.
Urotensin II-related peptide
Urotensin II-related peptide is a human urotensin II anague. Urotensin II-related peptide has high affinity for the UT receptor [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 342878-90-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1165.
Urotensin II-Related Peptide (human, mouse, rat)
Urotensin II-Related Peptide (human, mouse, rat) has a high affinity for urotensin II receptors in human and rat with Kds of 170 and 91 pM, respectively. In addition, it produced a long lasting hypotensive effect in anesthetized rats at 10 nmol/kg. Synonyms: Urotensin IIB (human, mouse, rat); H-Ala-Cys-Phe-Trp-Lys-Tyr-Cys-Val-OH (Disulfide bridge: Cys2-Cys7); L-alanyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-L-valine (2->7)-disulfide; UIIB (human, mouse, rat); URP (human, mouse, rat); N-{[(4R,7S,10S,13S,16S,19R)-19-(L-Alanylamino)-10-(4-aminobutyl)-16-benzyl-7-(4-hydroxybenzyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-valine. Grade: ≥95%. CAS No. 342878-90-4. Molecular formula: C49H64N10O10S2. Mole weight: 1017.22.
Ursocholic acid
Ursocholic acid, a bile acid present in mammalian bile, is converted to deoxycholic acid (UDC) by the mouse intestinal flora. Ursocholic acid acts as a gallstone dissolving agent in the liver through anti- apoptosis , anti-inflammatory, immunomodulatory, bile regulation, and coordinated changes in mitochondrial integrity and cell signaling, Ursocholic acid also has favorable effects on bones in patients with chronic cholestasis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 2955-27-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113212.
Ursocholic acid
Ursocholic acid. Group: Biochemicals. Alternative Names: (3a,5b,7b,12a)-3,7,12-Trihydroxycholan-24-oic acid; 3a,7b,12a-Trihydroxy-5b-cholanic acid; 3a,7b,12a-Trihydroxy-5b-cholan-24-oic acid. Grades: Highly Purified. CAS No. 2955-27-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C24H40O5. US Biological Life Sciences.
Worldwide
Ursocholic Acid
Ursocholic Acid. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Ursocholic acid, 3alpha,7beta,12alpha-Trihydroxy-5beta-cholanoic acid, 3alpha,7beta,12alpha-Trihydroxy-5beta-cholan-24-oic acid, 7beta-Hydroxyisocholic acid, 3alpha,7beta,12alpha-Trihydroxycholanic acid, 7-Epicholic acid, 3alpha,7beta,12alpha-Trihydroxy-5beta-cholanic acid,(3alpha,5beta,7beta,12alpha)-3,7,12-Trihydroxycholan-24-oic acid. CAS No. 2955-27-3. IUPAC Name: (4R)-4-[(3R,5S,7S,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid. Molecular formula: C24H40O5. Mole weight: 408.57. Catalog: APS2955273. SMILES: C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@@H]3[C@@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C. Format: Neat.
Ursodeoxycholic-1-methyl Ester (Ursodiol, 7b-Hydroxylithocholic Acid, Methyl Ester). Group: Biochemicals. Alternative Names: Ursodiol, 7b-Hydroxylithocholic Acid, Methyl Ester. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Ursodeoxycholic-2,2,4,4-d4 acid 3-sulfate disodium salt
?98 atom % D, ?98%. Group: Fluorescence/luminescence spectroscopy.
Ursodeoxycholic-2,2,4,4-d4 acid solution
100 ?g/mL in methanol, ?98 atom % D, ?98% (CP). Group: Fluorescence/luminescence spectroscopy.
Ursodeoxycholic acid
500 ?g/mL in methanol, certified reference material. Group: Bile acid standards.
Ursodeoxycholic acid
Ursodeoxycholic acid (Ursodeoxycholate) is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 ( TGR5 , GPCR19 ) and the farnesoid X receptor ( FXR ). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection. Orally active [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Ursodeoxycholate; Ursodiol; UDCA. CAS No. 128-13-2. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-13771.
Ursodeoxycholic acid
Ursodeoxycholic acid (INN, BAN and AAN), also known as ursodiol (USAN) and the abbreviation UDCA, from the root-word for bear urso, as bear bile contains the substance, is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Tauroursodiol. Product Category: Steroidal Compounds. Appearance: Solid. CAS No. 128-13-2. Molecular formula: C24H40O4. Mole weight: 392.57. Purity: 0.98. IUPACName: (4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-Dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid. Canonical SMILES: CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C. Density: 0.9985 g/cm³. ECNumber: 204-879-3. Product ID: ACM128132. Alfa Chemistry ISO 9001:2015 Certified.
Ursodeoxycholic Acid. Group: Biochemicals. Alternative Names: UDCA; 3a,7a-Dihydroxy-5b-cholan-24-oic acid. Grades: Highly Purified. CAS No. 128-13-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C24H40O4. US Biological Life Sciences.
Worldwide
Ursodeoxycholic Acid
Ursodeoxycholic acid (UDCS) is a cell protectant used extensively to mitigate hepatic and biliary diseases. Ursodeoxycholic acid may be used to study its specific activities that range from reduction of cholesterol absorpition, cholesterol gallstone dissolution to suppression of immune response.IC50: M1-family aminopeptidase: IC50=2.6 μM (Plasmodium falciparum 3D7); NTCP: IC50=3.6 μM (human); HCT-116: IC50=>50 μM (human); GBM: IC50=>50 μM (human) Asbt: Ki=75 μM (human). Uses: Gallstone-dissolving drugs; anti-neoplastic; for the prevention and treatment of cholesterol gallstones; reduces hydrophobic bile acids and decreases both lymphocyte reactivity and serum alkaline phosphatase levels,ic50: m1-family aminopeptidase: ic50=2.6 μm (plasmodium falciparum 3d7); ntcp: ic50=3.6 μm (human); hct-116: ic50=>50 μm (human); gbm: ic50=>50 μm (human) asbt: ki= 75 μm (human). Synonyms: 5beta-cholanic acid-3alpha,7beta-diol; Actigall; ursodeoxycholate; ursodiol; Ursodeoxycholic acid. Grade: ≥ 99.0%. CAS No. 128-13-2. Molecular formula: C24H40O4. Mole weight: 392.57.
Ursodeoxycholic acid-2,2,4,4-d4
Ursodeoxycholic acid-2,2,4,4-d 4 is the deuterium labeled Ursodeoxycholic acid (HY-13771). Ursodeoxycholic acid is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 (TGR5, GPCR19) and the farnesoid X receptor (FXR). Ursodeoxycholic acid can be used for the research of a variety of hepatic and gastrointestinal diseases. Ursodeoxycholic acid also reduces ACE2 expression and is beneficial for reducing SARS-CoV-2 infection[1][2][3][4][5]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 347841-46-7. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-113478S.
Ursodeoxycholic Acid Acyl- β-D-glucuronide, >85%
A metabolite of Ursodeoxycholic acid. Contains products of acyl migration which were not individually quantified. Group: Biochemicals. Alternative Names: 1-[(3α,5 β,7 β)-3,7-Dhydroxycholan-24-oate- β-D-glucopyranuronic Acid. Grades: Highly Purified. CAS No. 208038-28-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ursodeoxycholic acid-[d4]
Ursodeoxycholic acid-d4 (UDCA-d4) is a labelled UDCA. UDCA-d4 is intended for use as an internal standard for the quantification of UDCA by GC- or LC-MS. Synonyms: (3α,5β,7β)-3,7-Dihydroxy-cholan-24-oic-2,2,4,4,-d4; Ursodeoxycholic-2,2,4,4-d4 acid; Ursodeoxycholic acid-2,2,4,4-d4. Grade: ≥98% (CP); ≥98% atom D. CAS No. 347841-46-7. Molecular formula: C24H36D4O4. Mole weight: 396.60.
Ursodeoxycholic acid-D4
100 ?g/mL in methanol, certified reference material. Group: Bile acid standards.
Ursodeoxycholic acid-[d5]
Ursodeoxycholic Acid-d5 is a labelled analogue of Ursodeoxycholic Acid. Ursodeoxycholic Acid is one of metabolites of intestinal bacteria. Ursodeoxycholic Acid shows an effect of apoptosis suppression and reduction in gallstone formation. Synonyms: (3α,5β,7β)-3,7-Dihydroxycholan-24-oic Acid-d5; Ursodiol-d5; 7β-Hydroxylithocholic Acid-d5; 17β-(1-Methyl-3-carboxypropyl)etiocholane-3α,7β-diol-d5; Actigall-d5; Adursal-d5; Cholit-Ursan-d5; Delursan-d5; Desocol-d5; Destolit-d5; Deursil-d5; Ursodamor-d5. Grade: 95% by HPLC; 98% atom D. CAS No. 93701-18-9. Molecular formula: C24H35O4D5. Mole weight: 397.61.
Ursodeoxycholic Acid-d5 (Ursodiol-d5, 7b-Hydroxylithocholic Acid-d5). Group: Biochemicals. Alternative Names: Ursodiol-d5, 7b-Hydroxylithocholic Acid-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ursodeoxycholic acid methyl ester
Ursodeoxycholic acid methyl ester. Group: Biochemicals. Alternative Names: (3a,5b,7b)-3,7-Dihydroxycholan-24-oic acid. Grades: Highly Purified. CAS No. 10538-55-3. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C25H42O4. US Biological Life Sciences.
Worldwide
Ursodeoxycholic Acid Methyl Ester-[d5]
Ursodeoxycholic Acid Methyl Ester-[d5]. Uses: A precursor to manufacture udca (ursodeoxycholic acid). Synonyms: Ursodeoxycholic Acid D5 Methyl Ester. Grade: 95% atom D. CAS No. 93701-19-0. Molecular formula: C25H37D5O4. Mole weight: 411.63.
Ursodeoxycholic acid sodium
Ursodeoxycholic acid (Ursodeoxycholate) sodium is a secondary bile acid issued from the transformation of (cheno)deoxycholic acid by intestinal bacteria, acting as a key regulator of the intestinal barrier integrity and essential for lipid metabolism. Ursodeoxycholic acid sodium acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors, including G-protein coupled bile acid receptor 5 ( TGR5 , GPCR19 ) and the farnesoid X receptor ( FXR ). Ursodeoxycholic acid sodium can be used for the research of a variety of hepatic and gastrointestinal diseases. Orally active [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Ursodeoxycholate sodium; Ursodiol sodium; UCDA sodium. CAS No. 2898-95-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-13771A.
Ursodeoxycholic Acid, Sodium Salt
Ursodeoxycholic Acid, Sodium Salt. CAS No: 128-13-2
Sarchem Laboratories New Jersey NJ
Ursodiol
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy. Uses: Scientific research. Group: Natural products. Alternative Names: Prunol; Urson; Malol. CAS No. 77-52-1. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg. Product ID: HY-N0140.
Ursolic acid
Ursolic acid is a natural pentacyclic triterpenoid carboxylic acid displaying antitumor activity. It was shown to downregulate the MMP-2 and uPA expression, and also inhibit Na+/K+-ATPase activity (IC50 = 24.7 μM) as well as NF-κB activation in various cancer cell lines. Ursolic acid can induce apoptosis in cancer cells. Ursolic acid also has obvious antioxidant function, so it is widely used as a raw material for medicine and cosmetics. Uses: Antidepressant. Synonyms: NSC-167406; NSC-4060; NSC167406; NSC4060; NSC 167406; NSC 4060; Malol; Prunol; Urson; 3beta-Hydroxyurs-12-en-28-oic acid. Grade: ≥ 98%. CAS No. 77-52-1. Molecular formula: C30H48O3. Mole weight: 456.711.
Ursolic acid
Ursolic Acid is a Triterpene acid used in cosmetics, that also has STAT3 pathway inhibiting properties.Ursolic acid protects against muscle atrophy and boosts muscle growth (see also tomatidine. Group: Biochemicals. Alternative Names: (3 β)-3-Hydroxy-urs-12-en-28-oic Acid; (+)-Ursolic Acid; Bungeolic Acid; Malol; Merotaine; Neoage UR; Prunol; NSC 167406; NSC 4060; β-Ursolic Acid. Grades: Highly Purified. CAS No. 77-52-1. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C??H??O?, Molecular Weight: 456.7. US Biological Life Sciences.
Worldwide
Ursolic acid
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardseuropean pharmacopoeia (ph. eur.)pharmacopoeial standards.
Ursolic Acid
1, antioxidant, anti-microbial, anti-aging, anti-inflammatory effects 2, skin whitening. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3β-Hydroxy-12-ursen-28-ic acid. Product Category: Material of cosmetics. Appearance: White powder. CAS No. 77-52-1. Molecular formula: C30H48O3. Mole weight: 456.7. IUPACName: (1S,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid. Canonical SMILES: C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]2[C@H]1C)C)C(=O)O. Density: 1.026 g/ml. Product ID: ACM77521. Alfa Chemistry ISO 9001:2015 Certified.
Ursolic Acid
Ursolic Acid - Product ID: NST-10-19. Category: Triterpens. Alternative Names: Bungeolic acid, Malol, Merotaine, Prunol, Ursolisome, Urson, ?-Ursolic acid. Purity: 98%. Test method: HPLC. CAS No. 77-52-1. Pack Sizes: 5g, 10g, 25g, 50g. Appearance: White to beige coloured Powder. Molecular formula: C30H48O3. Mole weight: 456.7. Storage: +2 +8 °C.
Ursolic Acid
Ursolic Acid. CAS No: 77-52-1
Sarchem Laboratories New Jersey NJ
Ursolic acid acetate
Ursolic acid acetate (Acetylursolic acid), isolated from the aerial roots of Ficus microcarpa , exhibits cytotoxicity against KB cells with IC 50 of 8.4 μM [1]. Uses: Scientific research. Group: Natural products. Alternative Names: Acetylursolic acid; 3-Acetylursolic acid. CAS No. 7372-30-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-N2815.
Ursolic Acid-d3
Ursolic Acid-d3 is labelled Ursolic Acid(U850100) which is a Triterpene acid used in cosmetics. It also has STAT3 pathway inhibiting properties. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C30H45D3O3, Molecular Weight: 459.72. US Biological Life Sciences.
Worldwide
Ursolic acid (Standard)
Ursolic acid (Standard) is the analytical standard of Ursolic acid. This product is intended for research and analytical applications. Ursolic acid (Prunol) is a natural pentacyclic triterpenoid carboxylic acid, exerts anti-tumor effects and is an effective compound for cancer prevention and therapy. Uses: Scientific research. Group: Natural products. CAS No. 77-52-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0140R.
Ursonic Acid
Ursonic Acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ursomic acid; ursonic acid; ursonic acd; 3-oxo-ursolic acid; 3-Ketone. Product Category: Steroidal Compounds. Appearance: Powder. CAS No. 6246-46-4. Molecular formula: C30H46O3. Mole weight: 454.7. Purity: 0.98. IUPACName: (1S,2R,4aS,6aR,6aS,6bR,12aR,14bR)-1,2,6a,6b,9,9,12a-heptamethyl-10-oxo-1,2,3,4,5,6,6a,7,8,8a,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid. Canonical SMILES: CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(=O)C5(C)C)C)C)C2C1C)C)C(=O)O. Product ID: ACM6246464. Alfa Chemistry ISO 9001:2015 Certified.
USF1 human
recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
Usherin isoform B (3700-3711)
Usherin isoform B (3700-3711).
Usinic acid
Usinic acid. Group: Biochemicals. CAS No. 125-46-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
USL311
USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing tumor cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: USL-311; USL 311; USL311. Product Category: Antagonists. Appearance: Solid powder. CAS No. 1373268-67-7. Molecular formula: C24H34N6O. Mole weight: 422.58. Purity: >98%. IUPACName: 6-[4-(1-Propan-2-ylpiperidin-4-yl)-1,4-diazepan-1-yl]-N-pyridin-4-ylpyridine-2-carboxamide. Canonical SMILES: O=C(C1=NC(N2CCN(C3CCN(C(C)C)CC3)CCC2)=CC=C1)NC4=CC=NC=C4. Product ID: ACM1373268677. Alfa Chemistry ISO 9001:2015 Certified. Categories: US 311.
Usnic acid
Usnic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 125-46-2. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C18H16O7. US Biological Life Sciences.
Worldwide
Usnic acid
Usnic acid, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid has excellent anticancer and antimicrobial properties. Usnic acid significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1 [1]. Uses: Scientific research. Group: Natural products. CAS No. 125-46-2. Pack Sizes: 100 mg; 500 mg. Product ID: HY-N0656.
Usnic Acid
Usnic Acid - Product ID: NST-10-49. Category: Polyketides. Purity: 98%. Test method: HPLC. CAS No. 7562-61-0. Pack Sizes: 25g, 50g, 125g, 250g. Appearance: Brown fine powder. Molecular formula: C18H16O7. Mole weight: 344.32. Storage: +2 +8 °C.
Usnic Acid
Usnic acid, a lichen-derived secondary metabolite, has a unique dibenzofuran skeleton. Usnic acid has excellent anticancer and antimicrobial properties. Usnic acid significantly inhibits RANKL-mediated osteoclast formation and function by reducing the transcriptional and translational expression of NFATc1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,3(2H,9bH)-Dibenzofurandione, 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-. Product Category: Inhibitors. Appearance: Solid. CAS No. 125-46-2. Molecular formula: C18H16O7. Mole weight: 344.32. Purity: 0.98. Canonical SMILES: O=C(C1(C)C(OC2=C(C(C)=O)C(O)=C(C)C(O)=C12)=C3)C(C(C)=O)C3=O. Density: 1.54 g/cm³. Product ID: ACM125462. Alfa Chemistry ISO 9001:2015 Certified.
USP14 Inhibitor, IU1
The USP14 Inhibitor, IU1 controls the biological activity of USP14. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy.
A cell-permeable pyrrolylpyrrolidinyl-ethanone compound that directly targets proteasome-associated DUB (deubiquitinating enzyme) USP14 and acts as a potent, active-site-directed and reversible inhibitor of hUSP14 deubiquitinating catalytic activity (IC50=4.7uM for Ub-AMC hydrolysis) with excellent selectivity over proteasome-free USP14 and 8-other hDUBs including IsoT (IC50=100uM), UCH37, BAP1, UCH-L1, UCH-L3, USP15, USP2 and USP7 (IC50>700uM). Shown to enhance proteolysis in cells and induce degradation of misfolded toxic proteins like tau, TDP-43 and GFAP (glial fibrillary acidic protein) in coexpressed-wtMEFs at 50uM and offer protection against oxidative stress-induced cytotoxicity. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
USP15-IN-1
USP15-IN-1 is a potent USP15 inhibitor with an IC50 value of 3.76 ?M. USP15-IN-1 can be used for researching anticancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2260826-16-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148046.
USP1-IN-7
USP1-IN-7 (Compound 3) is an inhibitor for ubiquitin specific peptidase 1 ( USP1 ) and its cofactor UAF1 , with IC 50 ≤50 nM. USP1-IN-7 inhibits proliferation of MDA-MB-436 with IC 50 ≤50 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3033480-42-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161446.
USP25/28 inhibitor AZ1
USP25/28 inhibitor AZ1 (AZ1) is an orally active, selective, noncompetitive, dual ubiquitin specific protease (USP) 25/28 inhibitor with IC50s of 0.7 ?M and 0.6 ?M, respectively. USP25/28 inhibitor AZ1 attenuates colitis and tumorigenesis in the mice model[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZ1. CAS No. 2165322-94-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117370.
USP28-IN-4
USP28-IN-4 is a USP28 inhibitor (IC50=0.04 ?M) with high selectivity over USP2, USP7, USP8, USP9x, UCHL3 and UCHL5. USP28-IN-4 shows cytotoxicity against cancer cells, down-regulates the cellular level of c-Myc through ubiquitin-proteasome system. USP28-IN-4 also decreases the ankyrase-1/2 level in vitro. USP28-IN-4 enhance the sensitivity of colorectal cancer cells to Regorafenib (HY-10331)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2931509-15-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149230.
USP5-IN-1
USP5-IN-1 (compound 64) is a selective competitive inhibitor of USP5 zinc finger ubiquitin binding domain (ZnF-UBD) (KD=2.8 ?M). USP5-IN-1 competitively blocks the binding of ubiquitin to ZnF-UBD, inhibits the catalytic activity of USP5, and thus hinders the hydrolysis of ubiquitin chains. USP5-IN-1 can inhibit USP5 cleavage of Lys48-linked diubiquitin substrates in vitro and is a potential USP5 chemical probe and potential inhibitor of USP5-related cancers. Uses: Scientific research. Group: Signaling pathways. CAS No. 2851040-81-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139979.
USP7-797
USP7-797 (USP7-IN-7) is an orally available, selective USP7 inhibitor (IC50=0.5 nmol/L) with antitumor activity. USP7-797 reduces the level of MDM2, thereby increasing the stability and activity of p53, leading to cell cycle arrest and apoptosis. USP7-797 has low nanomolar cytotoxicity against p53 mutant cancer cell lines, p53 wild-type hematological tumors, and neuroblastoma cell lines[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: USP7-IN-7. CAS No. 2413944-70-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136910.
USP7-IN-13
USP7-IN-13 (Compound 101) is a USP7 inhibitor with an IC 50 value of 0.2-1 μM, which can be used for the study of multiple myeloma [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2305046-93-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160515.
USP7/USP47 inhibitor
USP7/USP47 inhibitor is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 ?M and 1.0 ?M, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1247825-37-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13487.
Ustekinumab
Ustekinumab is an anti- IL-12 / IL-23 IgG1κ human monoclonal antibody. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: Anti-Human IL-12/IL-23, Human Antibody. CAS No. 815610-63-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9909.
Ustilipid A
Ustilipid A is originally isolated from Ustilago maydie DSM 11494. It has the activity of antagonizing dopamine D1 and D2 receptors with the IC50 (μg/mL) of 30 and 5, respectively. Synonyms: [(2R,3S)-2,3,4-Trihydroxybutyl]2-O-hexanoyl-3-O-hexadecanoyl-4-O,6-O-diacetyl-beta-D-mannopyranoside. Molecular formula: C36H64O13. Mole weight: 704.88.
Ustilipid B
Ustilipid B is originally isolated from Ustilago maydie DSM 11494. It has the activity of antagonizing dopamine D1 and D2 receptors with the IC50 (μg/mL) of 16 and 7, respectively. Molecular formula: C34H60O13. Mole weight: 676.83.
Ustiloxin A
It is originally isolated from Ustilaginoidea virens. Ustiloxin A can inhibit the polymerization of tubulin with an IC50 of 0.7 μmol/L, and it also inhibits mitosis in various human tumor cell lines. Grade: ≥95%. CAS No. 143557-93-1. Molecular formula: C28H43N5O12S. Mole weight: 673.73.
Ustiloxin B
It is originally isolated from Ustilaginoidea virens. Ustiloxin B can inhibit the polymerization of tubulin with an IC50 of 2.8 μmol/L, and it also inhibits mitosis in various human tumor cell lines. Grade: ≥98%. CAS No. 151841-41-7. Molecular formula: C26H39N5O12S. Mole weight: 645.68.
Ustusol A
Ustusol A is produced by the strain of Aspergillus ustus. Synonyms: (3S,5S,9R,10S)-3,9,11-trihydroxydrim-7-en-6-one; 3β,9α,11-trihydroxy-6-oxodrim-7-ene; 1(4H)-Naphthalenone, 4a,5,6,7,8,8a-hexahydro-4,7-dihydroxy-4-(hydroxymethyl)-3,4a,8,8-tetramethyl-, (4R,4aS,7S,8aS)-. Grade: 98.0%. CAS No. 1175543-02-8. Molecular formula: C15H24O4. Mole weight: 268.35.
Ustusolate A
Ustusolate A is produced by Aspergillus ustus and exerts weak cytotoxicity against HL-60 and A549 cells with IC50 values of 20.6 and 30.0 microM, respectively. Synonyms: 6-O-(octa-2E,4E,6E-trienoyl)-12-hydroxy-6-epi-albrassitriol; 2,4,6-Octatrienoic acid, (1R,4S,4aS,8aS)-1,4,4a,5,6,7,8,8a-octahydro-4-hydroxy-3,4-bis(hydroxymethyl)-4a,8,8-trimethyl-1-naphthalenyl ester, (2E,4E,6E)-. Grade: ≥98%. CAS No. 1136611-58-9. Molecular formula: C23H34O5. Mole weight: 390.51.