A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Volinanserin is a potent and selective antagonist of 5-HT 2 receptor , with a K i of 0.36 nM, and shows 300-fold selectivity for 5-HT 2 receptor over 5-HT 1c , alpha-1 and DA D 2 receptors. Volinanserin has antipsychotic activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDL100907; M 100907. CAS No. 139290-65-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14940.
Volinanserin-d4 Hydrochloride Salt
A labeled serotonin 5-HT2A receptor antagonist. Used as potential controls in various biological studies. Group: Biochemicals. Alternative Names: (αR)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl-d4]-4-piperidinemethanol Hydrochloride; (+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl-d4]-4-piperidinemethanol Hydrochloride; (+)-MDL 100907-d4; M 100907-d4; MDL 100907-d4; R-MDL 100907-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Volinanserin Hydrochloride Salt
A serotonin 5-HT2A receptor antagonist. Used as potential controls in various biological studies. Group: Biochemicals. Alternative Names: (αR)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride; (+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride; (+)-MDL 100907; M 100907; MDL 100907; R-MDL 100907. Grades: Highly Purified. CAS No. 139290-65-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Volixibat
Volixibat (SHP626) is a highly selective, minimally absorbed, and competitive apical sodium-dependent bile acid transporter (ASBT) inhibitor. Volixibat has potential for treatment for non-alcoholic steatohepatitis (NASH) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHP626; LUM002. CAS No. 1025216-57-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101190.
Volociximab
Volociximab (M200) is a chimeric human/murine IgG4 antibody IIA1 targeting integrin α5β1 ( EC 50 =0.2 nM). Integrin α5β1 is a major fibronectin receptor involved in angiogenesis. Volociximab has antiangiogenic and antitumor activities and inhibits the proliferation of human umbilical vein vascular endothelial cells (HUVECs) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: M200; Eos 200-4. CAS No. 558480-40-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99333.
Vomicine
Vomicine. Group: Biochemicals. Alternative Names: Strychnicine; Struxine. Grades: Plant Grade. CAS No. 125-15-5. Pack Sizes: 10mg. Molecular Formula: C22H24N2O4, Molecular Weight: 380.437. US Biological Life Sciences.
Worldwide
Vomifoliol
Vomifoliol isolated from the herbs of Vitis vinifera. Synonyms: (1S)-1-Hydroxy-1-[(1E,3R)-3-hydroxy-1-butenyl]-2,6,6-trimethyl-2-cyclohexene-4-one; (6S,9R)-vomifoliol. Grade: 0.97. CAS No. 23526-45-6. Molecular formula: C13H20O3. Mole weight: 224.3.
vomifoliol dehydrogenase
Oxidizes vomifoliol to dehydrovomifoliol; involved in the metabolism of abscisic acid in Corynebacterium sp. Group: Enzymes. Synonyms: vomifoliol 4'-dehydrogenase; vomifoliol:NAD+ 4'-oxidoreductase. Enzyme Commission Number: EC 1.1.1.221. CAS No. 94949-18-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0127; vomifoliol dehydrogenase; EC 1.1.1.221; 94949-18-5; vomifoliol 4'-dehydrogenase; vomifoliol:NAD+ 4'-oxidoreductase. Cat No: EXWM-0127.
vomilenine glucosyltransferase
The indole alkaloid raucaffricine accumulates during the culture of Rauvolfia cell suspensions. Group: Enzymes. Synonyms: UDPG:vomilenine 21-β-D-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.219. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2447; vomilenine glucosyltransferase; EC 2.4.1.219; UDPG:vomilenine 21-β-D-glucosyltransferase. Cat No: EXWM-2447.
vomilenine reductase
Forms part of the ajmaline biosynthesis pathway. Group: Enzymes. Enzyme Commission Number: EC 1.5.1.32. CAS No. 462127-03-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1514; vomilenine reductase; EC 1.5.1.32; 462127-03-3. Cat No: EXWM-1514.
Vonafexor
Vonafexor (EYP001) is an orally active, non-steroidal and selective FXR agonist. Vonafexor shows significant HBsAg reduction when combined with Peg-IFN&alpha. Vonafexor can be used for anti- HBV research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EYP001. CAS No. 1192171-69-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109197.
Vonoprazan
Vonoprazan (TAK-438 free base), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB) , with antisecretory activity. Vonoprazan inhibits H + ,K + -ATPase activity in porcine gastric microsomes with an IC 50 of 19 nM at pH 6.5. Vonoprazan is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan can be used for eradication of Helicobacter pylori [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-438 free base. CAS No. 881681-00-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-100007.
Vonoprazan-[d3]
Vonoprazan-[d3] is a labelled Vonoprazan, a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+ ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. Synonyms: Vonoprazan-d3. Molecular formula: C17H13D3FN3O2S. Mole weight: 348.4.
Vonoprazan Fumarate
TAK-438 is an orally active potassium-competitive acid blocker which inhibits H+, K+-ATPase activity with an IC50 of 19 nM. CAS No. 1260141-27-2. Product ID: API1260141272. Mole weight: 461.46. Category: Active Pharmaceutical Ingredients.
Vonoprazan Fumarate
Vonoprazan Fumarate (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB) , with antisecretory activity. Vonoprazan Fumarate inhibits H + ,K + -ATPase activity in porcine gastric microsomes with an IC 50 of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-438. CAS No. 881681-01-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-15295.
Vonoprazan Impurity 27
Vonoprazan Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 122453-85-4. Molecular formula: C11H8N2. Mole weight: 168.2. Catalog: APB122453854.
Vonoprazan Impurity 34
Vonoprazan Impurity 34. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1240948-72-4. Molecular formula: C11H6ClFN2. Mole weight: 220.63. Catalog: APB1240948724.
Vonoprazan Impurity 36
Vonoprazan Impurity 36. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1060802-18-7. Molecular formula: C5H3Cl2NO2S. Mole weight: 212.04. Catalog: APB1060802187.
Vonoprazan Impurity 51
Vonoprazan Impurity 51. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1240949-51-2. Molecular formula: C11H7FN2. Mole weight: 186.19. Catalog: APB1240949512.
Vonoprazan Impurity 64
Vonoprazan Impurity 64. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1240948-77-9. Molecular formula: C11H7FN2. Mole weight: 186.19. Catalog: APB1240948779.
VO-OHpic
VO-OHpic. Group: Biochemicals. Grades: Purified. CAS No. 675848-25-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
VO-Ohpic trihydrate
VO-Ohpic trihydrate is a highly potent inhibitor of PTEN with an IC 50 of 46±10 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 476310-60-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13074.
A vanadium complex that acts as a highly potent and specific inhibitor of Phosphatase and Tensin Homologue Deleted on Chromosome 10 (PTEN). Group: Biochemicals. Alternative Names: VO(Hhpic-O,O) (Hhpic-O,N)(H2O)]. 3H2O. Grades: Highly Purified. CAS No. 476310-60-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
VOPc
VOPc. Uses: Designed for use in research and industrial production. Additional or Alternative Names: VANADYL(IV)-PHTHALOCYANINE;VANADYL PHTHALOCYANINE;VANADIUM(IV) OXIDE PHTHALOCYANINE;VOPC;31h-phthalocyaninato(2-)-n29,n39,n31,n32]-oxo[29(sp-5-12)-vanadiu;PHTHALOCYANINE, VANADYL;OXO(PHTHALOCYANINATO)VANADIUM(IV);Oxyvanadium phthalocyanine. Product Category: Photonic and Optical Device. CAS No. 13930-88-6. Molecular formula: C32H16N8OV. Mole weight: 579.47. Product ID: ACM13930886. Alfa Chemistry ISO 9001:2015 Certified. Categories: Volcano.
Vopimetostat
TNG-462 is an orally active and selective PRMT5 inhibitor with anti-tumor activity against methylthioadenosine phosphorylase (MTAP) deficiency and/or methylthioadenosine (MTA) accumulation cancers[1][2].. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TNG-462. CAS No. 2760483-96-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156680.
Vopratelimab
Vopratelimab (JTX-2011) is a humanized immunoglobulin G1-kappa agonist monoclonal antibody that pecifically binds to the Inducible CO-Stimulator of T cells (ICOS). Vopratelimab retains species cross-reactivity with affinities of 0.93 nM to hICOS, 0.46 nM to cynomolgus ICOS, 3.7 nM to rat ICOS, and 0.64 nM to mICOS. Vopratelimab has antitumor immune response [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: JTX 2011. CAS No. 2039148-04-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99382.
Vorapaxar
Vorapaxar (SCH 530348), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist ( K i =8.1 nM). Vorapaxar (SCH 530348) inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 530348. CAS No. 618385-01-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10119.
Vorapaxar-[d5]
One of the isotopic labelled form of Vorapaxar, which has been found to be an antiplatelet agent and could be potentially effective against atherothrombosis. Synonyms: (1,1,2,2,2-D5)ethyl N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1-methyl-3-oxo-dodecahydronaphtho[2,3-c]furan-6-yl]carbamate. Grade: >98%. Molecular formula: C29H28D5FN2O4. Mole weight: 497.61.
Vorapaxar sulfate
Vorapaxar sulfate (SCH 530348 sulfate), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist ( K i =8.1 nM). Vorapaxar sulfate inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 530348 sulfate. CAS No. 705260-08-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10119A.
Vorasidenib (AG-881) is an orally available, brain penetrant second-generation dual mutant isocitrate dehydrogenases 1 and 2 (mIDH1/2) inhibitor. Vorasidenib (AG-881) exhibits nanomolar inhibition of (D)-2-hydroxyglutarate (D-2-HG), and the IC 50 ranges of 0.04~22 nM against IDH1 R132C, IDH1 R132G, IDH1 R132H and IDH1 R132S and 7~14 nM against IDH2 R140Q and 130 nM against IDH2 R172K. Vorasidenib can be used for the study of grade 2 astrocytoma or oligodendroglioma with a susceptible IDH1/2 mutation [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AG-881. CAS No. 1644545-52-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-104042.
Vorbipiprant
Vorbipiprant (CR6086) is an orally active EP4 receptor antagonist with high selectivity for the human EP4 receptor (Ki: 16.6 nM). Vorbipiprant has immunomodulatory, anti-inflammatory, antitumor, and anti-angiogenic activities. Vorbipiprant can inhibit the expression of multiple pro-inflammatory cytokines and the activation of immune cells, and convert "cold" tumors unresponsive to immune checkpoint inhibitors into "hot" tumors. Vorbipiprant is used in the research of diseases such as rheumatoid arthritis and colon cancer[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CR6086. CAS No. 1417742-86-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156649.
Voreloxin
Voreloxin (SNS-595; Vosaroxin; AG 7352) is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNS-595; Vosaroxin; AG 7352. CAS No. 175414-77-4. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-10534.
Voreloxin Hydrochloride
Voreloxin Hydrochloride is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNS-595 Hydrochloride; Vosaroxin Hydrochloride; AG 7352 Hydrochloride. CAS No. 175519-16-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16518.
Voriconazole
Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: UK-109496. CAS No. 137234-62-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-76200.
Voriconazole is an antifungal medication used to treat a number of fungal infections, including aspergillosis, candidemia, and esophageal candidiasis. Synonyms: UK-109496; UK 109496; UK109496; UK109,496; UK-109,496; UK 109,496; Voriconazole; Vfend. Grade: >98%. CAS No. 137234-62-9. Molecular formula: C16H14F3N5O. Mole weight: 349.31.
Voriconazole
1g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C16H14F3N5O. CAS No. 137234-62-9. Prepack ID 78448300-1g. Molecular Weight 349.31. See USA prepack pricing.
Voriconazole
25mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C16H14F3N5O. CAS No. 137234-62-9. Prepack ID 78448300-25mg. Molecular Weight 349.31. See USA prepack pricing.
Voriconazole
An ergosterol biosynthesis inhibitor. Anti-fungal; sterol 14α-demethylase inhibitor. Group: Biochemicals. Alternative Names: (aR,bS)-a-(2,4-Difluorophenyl)-5-fluoro-b-methyl-a-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol; UK-109496. Grades: Highly Purified. CAS No. 137234-62-9. Pack Sizes: 1g, 5g. Molecular Formula: C16H14F3N5O, Molecular Weight: 349.31. US Biological Life Sciences.
Worldwide
Voriconazole 99+.9% (HPLC)
Voriconazole 99+.9% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
Voriconazole-d3
Voriconazole-d 3 is the deuterium labeled Voriconazole. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: UK-109496-d3. CAS No. 1217661-14-7. Pack Sizes: 500 μg; 1 mg. Product ID: HY-76200S.
Voriconazole-[d3]
Voriconazole-[d3] is the labelled analogue of Voriconazole, which has been found to be an ergosterol biosynthesis inhibitor and could be used as an antifungal agent. Synonyms: (±)-Voriconazole-d3; (αR,βS)-α-(2,4-Difluorophenyl)-5-fluoro-β-(methyl-d3)-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol; UK-109496-d3; VRC-d3; Vfend-d3; Voriconazol-d3. Grade: 95% by HPLC; 98% atom D. CAS No. 1217661-14-7. Molecular formula: C16H11D3F3N5O. Mole weight: 352.34.
Labeled Vorizonazole, used as an antifungal. An Ergosterol Biosynthesis inhibitor. Group: Biochemicals. Alternative Names: (aR,bS)-a-(2,4-Difluorophenyl)-5-fluoro-b-methyl-d3-a-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol; UK-109496-d3. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Voriconazole-[d3] N-Oxide
Voriconazole-[d3] N-Oxide is the labelled analogue of Voriconazole, which has been found to be an ergosterol biosynthesis inhibitor and could be used as an antifungal agent. Synonyms: Voriconazole-d3 N-Oxide; (αR,βS)-α-(2,4-Difluorophenyl)-5-fluoro-β-methyl-d3-α-(1H-1,2,4-triazol-1-ylmethyl)-1-oxide-4-pyrimidineethanol. Grade: 95% by HPLC; 98% atom D. CAS No. 1217851-84-7. Molecular formula: C16H11D3F3N5O2. Mole weight: 368.33.
Voriconazole-d3 N-Oxide
A labeled metabolite of Voriconazole. Group: Biochemicals. Alternative Names: (αR, βS)-α-(2,4-Difluorophenyl)-5-fluoro- β-methyl-d3-α-(1H-1,2,4-triazol-1-ylmethyl)-1-oxide-4-pyrimidineethanol; UK 121265-d3. Grades: Highly Purified. Pack Sizes: 0.25mg. US Biological Life Sciences.
Worldwide
Voriconazole N-oxide
Voriconazole N-oxide (Voriconazole oxynitride) is a potent antifungal agent. Voriconazole N-oxide has phototoxicity and photocarcinogenicity. Voriconazole N-oxide does not sensitize keratinocytes to ultraviolet B (UVB) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Voriconazole oxynitride. CAS No. 618109-05-0. Pack Sizes: 1 mg. Product ID: HY-137989.
Voriconazole N-oxide
Voriconazole N-oxide. Group: Biochemicals. Alternative Names: (a-R,b-S)-a-(2,4-Difluorophenyl)-5-fluoro-b-methyl-a-(1H-1,2,4-triazol-1-ylmethyl)-1-oxide-4-pyrimidineethanol; UK 121265. Grades: Highly Purified. CAS No. 618109-05-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C16H14F3N5O2. US Biological Life Sciences.
Worldwide
Voriconazole N-oxide
Voriconazole N-oxide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (αR,βS)-α-(2,4-Difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-1-oxide-4-pyrimidineethanol; UK 121265. Product Category: Heterocyclic Organic Compound. Appearance: Off-White Solid. CAS No. 618109-05-0. Molecular formula: C16H14F3N5O2. Mole weight: 365.31. Product ID: ACM618109050. Alfa Chemistry ISO 9001:2015 Certified.
Voriconazole Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Voriconazole Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Voriconazole Related Compound C
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Voriconazole Related Compound D
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Voriconazole Related Compound F
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Voriconazole solution
2.0 mg/mL in methanol, ampule of 1 mL, certified reference material. Group: Antifungals standards.
Vorinostat
Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1 , HDAC2 and HDAC3 (Class I) , HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV) , with ID 50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis [1] [4]. Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification [7]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAHA; Suberoylanilide hydroxamic acid. CAS No. 149647-78-9. Pack Sizes: 10 mM * 1 mL; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-10221.
Vorinostat
Vorinostat (rINN) also known as suberanilohydroxamic acid (suberoyl+anilide+hydroxamic acid abbreviated as SAHA) is a member of a larger class of compounds that inhibit histone deacetylases (HDAC). Histone deacetylase inhibitors (HDI) have a broad spectrum of epigenetic activities.Vorinostat is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL) when the disease persists, gets worse, or comes back during or after treatment with other medicines. The compound was developed by Columbia University chemist Ronald Breslow and Memorial Sloan-Kettering researcher Paul Marks. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Suberoylanilidehydroxamic Acid;N-Hydroxy-N-phenyloctanediamide;Vorinostat/SAHA;Suberoylanilide Hydroxamic Acid. Product Category: Inhibitors. Appearance: White crystalline solid. CAS No. 149647-78-9. Molecular formula: C14H20N2O3. Mole weight: 264.32. Purity: 0.9962. Density: 1.174 g/cm³. Product ID: ACM149647789. Alfa Chemistry ISO 9001:2015 Certified.
Vorinostat-[d5]
SAHA-d5 is a labelled suberoylanilide hydroxamic acid (SAHA), an HDAC inhibitor. Synonyms: Vorinostat D5. Grade: 98% by HPLC; 98% atom D. CAS No. 1132749-48-4. Molecular formula: C14H15D5N2O3. Mole weight: 269.35.
Vornorexant
Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively. Vornorexant exhibits potent sleep-promoting effects in vivo and can be used for insomnia research research. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ORN-0829; TS-142. CAS No. 1517965-94-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139559.
Vorolanib
Vorolanib (CM082) is an orally active, potent multikinase VEGFR/PDGFR inhibitor. Vorolanib is a potent ATP-binding cassette (ABC) transporter inhibitor. Vorolanib is an angiogenesis inhibitor and has antitumor activity combined with ZD1839 (HY-50895) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CM082; X-82. CAS No. 1013920-15-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109019.
Vortioxetine
Vortioxetine (Lu AA 21004) is an antagonist of 5-HT 3A and 5-HT 7 receptors ( K i : 3.7 nM, 19 nM) and an inhibitor of serotonin transporter ( SERT ) ( K i : 1.6 nM), as well as a 5-HT 1A agonist and a partial agonist of 5-HT 1B ( K i : 15 nM, 33 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu AA 21004. CAS No. 508233-74-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15414.
Vortioxetine-[d8]
One of the isotopic labelled form of Vortioxetine,which is a 5-HT receptor inhibitor as well as a serotonin transporter, and has been found to be an atypical antidepressant. Synonyms: 1-[2-[(2,4-Dimethylphenyl)thio]phenyl]piperazine-d8; 1-[2-(2,4-Dimethylphenylsulfanyl)phenyl]piperazine-d8. Grade: ≥90%. CAS No. 2140316-62-5. Molecular formula: C18H14D8N2S. Mole weight: 306.50.
Vortioxetine-[d8] HCl
An isotope labelled derivative of Vortioxetine. Vortioxetine is an antidepressant medication that is prescribed to treat depression. Synonyms: 1-[2-[[2,4-Di(methyl)phenyl]thio]phenyl]piperazine-2,2,3,3,5,5,6,6-d8. Grade: 95% by HPLC; 98% atom D. Molecular formula: C18H15D8ClN2S. Mole weight: 342.91.
Vortioxetine Glucose Adduct
Vortioxetine Glucose Adduct. Uses: For analytical and research use. Group: Impurity standards. Pack Sizes: 10MG. Catalog: APS013742. Format: Neat. Shipping: Room Temperature.
Vortioxetine hydrobromide
Vortioxetine (Lu AA 21004) hydrobromide is an antagonist of 5-HT 3A and 5-HT 7 receptors (K i : 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (K i : 1.6 nM), as well as a 5-HT 1A agonist and a partial 5-HT 1B agonist (K i : 15 nM, 33 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Lu AA21004 hydrobromide. CAS No. 960203-27-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15414A.
Vortioxetine Hydrobromide
Antidepressant. Alternative Names: Vortioxetine HBr. Brintellix. Trintellix. CAS No. 960203-27-4. Product ID: API960203274. Molecular formula: C18H23BrN2S. Mole weight: 379.4. EINECS: 696-022-9. SMILES: CC1=CC(=C(C=C1)SC2=CC=CC=C2N3CCNCC3)C.Br. Appearance: White to Light Yellow Powder. Category: Antidepressant APIs.