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Product
VU 0155041 sodium salt VU 0155041 sodium salt. Group: Biochemicals. Grades: Purified. CAS No. 1259372-69-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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VU0155041, Sodium Salt (cis-2- (3, 5-Dichlorophenyl carbamoyl ) cyclohexane carboxyl ic Acid Sodium Salt) A highly potent, selective positive allosteric modulator for mGlu receptor subtype 4 (EC50 = 0.8 and 0.7uM at human and rat mGlu4 receptors respectively). Does not interact with other mGluR subtypes. Significant antiparkinsonian effects in two preclinical rodent models of Parkinson's disease when administered intracerebroventri cularlly (icv). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
VU0155069 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
VU 0155069 VU 0155069. Group: Biochemicals. Grades: Purified. CAS No. 1130067-06-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU0238429 solubility: ?20 mg/mL in DMSO. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
VU 0238429 VU 0238429. Group: Biochemicals. Grades: Purified. CAS No. 1160247-92-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU0240551 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
VU 0240551 VU 0240551. Group: Biochemicals. Grades: Purified. CAS No. 893990-34-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU 0240551 VU 0240551 is a potent neuronal K-Cl cotransporter KCC2 inhibitor (IC50=560 nM) and is selective versus NKCC1. VU 0240551 also inhibits hERG and L-type Ca2+ channels. VU 0240551 attenuates GABA-induced hyperpolarization of P cells, produces a positive shift in the P cell GABA reversal potential and enhances P cell synaptic transmission[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 893990-34-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16689. MedChemExpress MCE
VU 0255035 VU 0255035. Group: Biochemicals. Grades: Purified. CAS No. 1135243-19-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU 0255035 VU0255035 is a highly selective and competitive M1 mAChR antagonist. VU0255035 blocks M1 mAChR signals to reduce epileptic seizures and regulate neuronal membrane potential. VU0255035 can be used in research related to central nervous system diseases, such as epilepsy, Parkinson's disease, and dystonia[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VU 255035. CAS No. 1135243-19-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108234. MedChemExpress MCE
VU0255035 hydrate ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
VU 0285683 VU 0285683. Group: Biochemicals. Alternative Names: 3-(2-Pyridyl)-5-(3-fluoro-5-cyanophenyl)-1,2,4-oxadiazole. Grades: Highly Purified. CAS No. 327056-22-4. Pack Sizes: 10mg. Molecular Formula: C14H7FN4O, Molecular Weight: 266.23. US Biological Life Sciences. USBiological 4
Worldwide
VU 0357017 hydrochloride VU 0357017 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1135242-13-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU0357017 monohydrochloride ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
VU0357121 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
VU 0357121 VU 0357121. Group: Biochemicals. Alternative Names: 4-Butoxy-N-(2,4-difluorophenyl)-benzamide. Grades: Highly Purified. CAS No. 433967-28-3. Pack Sizes: 25mg. Molecular Formula: C17H17F2NO2, Molecular Weight: 305.32. US Biological Life Sciences. USBiological 4
Worldwide
VU0359595 VU0359595 (CID-53361951; ML-270) is a potent and selective pharmacological phospholipase D1 (PLD1) inhibitor with an IC50 of 3.7 nM. VU0359595 is >1700-fold selective for PLD1 over PLD2 (IC50 of 6.4 ?M). VU0359595 can be used for the research of cancer, diabetes, neurodegenerative and inflammatory diseases[1][2][3][4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CID-53361951; ML-270. CAS No. 1246303-14-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101293. MedChemExpress MCE
VU0359595 ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
VU0360172 VU0360172 is a potent and selective mGlu5 receptor positive allosteric modulator with an EC 50 value of 16 nM and a K i of 195 nM, respectively. VU0360172 stimulates polyphosphoinositide (PI) hydrolysis in vivo , which is abrogated in mGlu5 receptors gene deleted mice [1]. VU0360172 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 1310012-12-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-120589. MedChemExpress MCE
VU 0360172 VU 0360172. Group: Biochemicals. Alternative Names: N-Cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]-3-pyridinecarboxamide Hydrochloride. Grades: Highly Purified. CAS No. 1309976-62-2. Pack Sizes: 10mg. Molecular Formula: C18H16ClFN2O, Molecular Weight: 330.78. US Biological Life Sciences. USBiological 4
Worldwide
VU 0360172 hydrochloride VU 0360172 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1309976-62-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU 0360223 VU 0360223. Group: Biochemicals. Grades: Purified. CAS No. 1274859-33-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU0361737 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
VU 0361737 VU 0361737. Group: Biochemicals. Grades: Purified. CAS No. 1161205-04-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU0364289 VU0364289 is a highly selective mGlu5 positive allosteric modulator (PAM) (binds to the MPEP (HY-14609A) site), with an EC 50 of 1.6 μM. VU0364289 can reverse amphetamine-induced hyperlocomotion in a dose-dependent manner, which can be used for schizophrenia and other psychiatric research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1242443-29-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120727. MedChemExpress MCE
VU0364439 VU0364439 is a positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4). Uses: Designed for use in research and industrial production. Additional or Alternative Names: VU0364439, VU-0364439, VU 0364439. Product Category: Others. Appearance: Solid powder. CAS No. 1246086-78-1. Molecular formula: C18H13Cl2N3O3S. Mole weight: 422.28. Purity: >98%. IUPACName: N-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide. Canonical SMILES: O=C(C1=NC=CC=C1)NC2=CC=C(S(=O)(NC3=CC=CC=C3Cl)=O)C(Cl)=C2. Product ID: ACM1246086781. Alfa Chemistry — ISO 9001:2015 Certified. Categories: CS-1000. Alfa Chemistry.
VU 0364439 VU 0364439. Group: Biochemicals. Grades: Purified. CAS No. 1246086-78-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU0364739 VU0364739 is a selective PLD2 inhibitor (IC50: 22 nM). VU0364739 decreases cancer cell proliferation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1244639-78-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-150412. MedChemExpress MCE
VU 0364739 hydrochloride VU 0364739 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1244640-48-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU0364770 VU0364770 is a selective and potent positive allosteric modulator ( PAM ) of mGlu4. VU0346770 exhibits EC 50 s of 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor , respectively. VU0364770 exhibits antagonist activity at mGlu5 with a potency of 17.9 μM and PAM activity at mGlu6 with a potency of 6.8 μM. VU0364770 also possesses activity at MAO with K i values of 8.5 and 0.72 μM for human MAO-A and human MAO-B, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 61350-00-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100588. MedChemExpress MCE
VU 0364770 VU 0364770. Group: Biochemicals. Grades: Purified. CAS No. 61350-00-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU0364770 hydrochloride VU0364770 hydrochloride is a selective and potent positive allosteric modulator ( PAM ) of mGlu4. VU0346770 hydrochloride exhibits EC 50 s of 290 nM and 1.1 μM at rat mGlu4 and human mGlu4 receptor , respectively. VU0364770 hydrochloride exhibits antagonist activity at mGlu5 with a potency of 17.9 μM and PAM activity at mGlu6 with a potency of 6.8 μM. VU0364770 hydrochloride also possesses activity at MAO with K i values of 8.5 and 0.72 μM for human MAO-A and human MAO-B, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1414842-70-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100588A. MedChemExpress MCE
VU 0365114 VU 0365114. Group: Biochemicals. Grades: Purified. CAS No. 1208222-39-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU0405601 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
VU0420373 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
VU0463271 VU0463271 is a selective KCC2 antagonist, with an IC50 of 61 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 1391737-01-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110110. MedChemExpress MCE
VU0463271 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
VU 0463271 VU 0463271. Group: Biochemicals. Grades: Purified. CAS No. 1391737-01-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU0463597 VU0463597, also known as ML-289, is a negative allosteric modulator of mGlu3 (IC50 = 0.66 μM) that displays 15-fold selectivity over mGlu2 and inactivity against mGlu5.1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: VU0463597, VU 0463597, VU-0463597, ML-289, ML 289; ML289. Product Category: Others. Appearance: Solid powder. CAS No. 1382481-79-9. Molecular formula: C22H23NO3. Mole weight: 349.43. Purity: >98%. IUPACName: [(3R)-1-({4-[2-(4-methoxyphenyl)ethynyl]phenyl}carbonyl)piperidin-3-yl]methanol. Canonical SMILES: OC[C@H]1CN(C(C2=CC=C(C#CC3=CC=C(OC)C=C3)C=C2)=O)CCC1. Product ID: ACM1382481799. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
VU0486321 VU0486321 is a compound in a class of mGlu1 positive allosteric modulators (PAMs). VU0486321 maintains acceptable mGlu1 PAM potency, DMPK profile, CNS permeability, and mGluR selectivity. Uses: Scientific research. Group: Signaling pathways. CAS No. 1816301-67-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-118179. MedChemExpress MCE
VU0486846 VU0486846 is an orally active and selective muscarinic acetylcholine receptor M1 positive allosteric modulator (PAM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1788055-11-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-121806. MedChemExpress MCE
VU0529331 VU0529331 is a modestly selective non-GIRK1-containing G protein-gated, inwardly-rectifying, potassium channel (non-GIRK1/X) activator, with EC50s of 5.1 μM and 5.2 μM for GIRK2 and GIRK1/2 in HEK293 cells, respectively, also effective on GIRK4 homomeric channel[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1286725-49-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112705. MedChemExpress MCE
VU0650786 VU0650786 is a potent and selective CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM), with an IC50 of 392 nM. VU0650786 has antidepressant and anxiolytic activity in rodents[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1809085-30-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108710. MedChemExpress MCE
VU 10010 VU 10010. Group: Biochemicals. Grades: Purified. CAS No. 633283-39-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU 152100 VU 152100. Group: Biochemicals. Grades: Purified. CAS No. 409351-28-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU 1545 VU 1545. Group: Biochemicals. Grades: Purified. CAS No. 890764-63-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU 29 VU 29. Group: Biochemicals. Grades: Purified. CAS No. 890764-36-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU-29 VU-29 is a positive allosteric modulator of metabotropic glutamate 5 (mGlu5) receptor ( EC 50 =9 nM and K i =244 nM for rmGluR5). VU-29 is selective for mGluR5 relative to other mGluR subtypes (EC 50 : rmGluR1/rmGluR2=557 nM/1.5 μM; hmGluR4=154 nM) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 890764-36-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107508. MedChemExpress MCE
VU590 VU590 is a potent and moderately selective ROMK (Kir1.1) inhibitor, with an IC 50 of 290 nM. VU590 also inhibits Kir7.1 , with an IC 50 of 8 μM. VU590 is not a good probe of ROMK function in the kidney [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 313505-85-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108595. MedChemExpress MCE
VU 590 dihydrochloride VU 590 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 313505-85-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU591 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
VU 591 hydrochloride VU 591 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1315380-70-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VU6005649 VU6005649 is a CNS penetrant mGlu7/8 receptor agonist with EC50s of 0.65 ?M and 2.6 ?M for mGlu7 receptor and mGlu8 receptor, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 2137047-43-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107982. MedChemExpress MCE
VU6036720 VU6036720 is a potent and specific in vitro inhibitor of Kir4.1/5.1. VU6036720 can inhibit Kir4.1/5.1 channels with an IC 50 value of 0.24 μM. VU6036720 can be used for the research of brain and kidney [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3026597-12-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-148304. MedChemExpress MCE
VUAA1 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
Vudalimab Vudalimab is a potent dual PD-1 and CTLA-4 inhibitor as a fully humanized bispecific monoclonal antibody. Vudalimab targets immune checkpoint receptors PD-1 and CTLA-4 and promotes tumor-selective T-cell activation [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2329669-72-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99166. MedChemExpress MCE
VUF10166 VUF10166 is a potent and high-affinity 5-HT 3 receptor antagonist, with K i values of 0.04 nM (5-HT 3 A) and 22 nM (5-HT 3 AB). VUF10166 inhibits 5-HT-induced responses at 5-HT 3 A and 5-HT 3 AB receptors at nanomolar concentrations. At 5-HT 3 receptor , VUF10166 at higher concentrations also acts as a partial agonist, with an EC 50 of 5.2 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 155584-74-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100552. MedChemExpress MCE
VUF 10166 VUF 10166. Group: Biochemicals. Grades: Purified. CAS No. 155584-74-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VUF 10460 VUF 10460. Group: Biochemicals. Grades: Purified. CAS No. 1028327-66-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VUF10661 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
VUF 11207 fumarate VUF 11207 fumarate. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VUF11207 fumarate VUF11207 fumarate is a CXCR7 agonist that binds specifically to CXCR7. VUF11207 fumarate reduces CXCL12-mediated osteoclastogenesis and bone resorption by inhibiting ERK phosphorylation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1785665-61-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110318. MedChemExpress MCE
VUF11207 trifluoroacetate salt ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
VUF 5574 VUF 5574. Group: Biochemicals. Grades: Purified. CAS No. 280570-45-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VUF 5681 dihydrobromide VUF 5681 dihydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 639089-06-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VUF 8430 dihydrobromide ?97% (NMR). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
VUF 8430 dihydrobromide VUF 8430 dihydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 100130-32-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
VUF 8430 dihydrobromide VUF 8430 (dihydrobromide) is a potent and selective histamine H4 receptor agonist with a K i of 31.6 nM and an EC 50 of 50 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 100130-32-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-107555. MedChemExpress MCE
vulcanization agents vulcanization agents. Group: Polymers. Alfa Chemistry Materials 3

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