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| Product | Description | |
|---|---|---|
| Vardenafil hydrochloride EP impurity C | Vardenafil hydrochloride EP impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1255919-03-9. Molecular formula: C38H46N10O8S2. Mole weight: 834.96. Catalog: APB1255919039. |  |
| Vardenafil hydrochloride trihydrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Vardenafil hydrochloride trihydrate | Vardenafil hydrochloride trihydrate is a selective and orally active inhibitor of phosphodiesterase-5 ( PDE5 ), with an IC 50 of 0.7 nM. Vardenafil hydrochloride trihydrate shows inhibitory towards PDE1, PDE6 with IC 50 s of 180 nM, and 11 nM, while IC 50 s are >1000 nM for PDE3 and PDE4 [1]. Vardenafil hydrochloride trihydrate competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels [2]. Vardenafil hydrochloride trihydrate can be used for the research of erectile dysfunction, hepatitis, diabetes [1]-[6]. Uses: Scientific research. Group: Natural products. CAS No. 330808-88-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0442B. |  |
| Vardenafil Impurity 1 | An impurity of Vardenafil. Vardenafil is a phosphodiesterase type 5 (PDE5) inhibitor used for the treatment of erectile dysfunction. Synonyms: (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2yl]pyrazine-2-carboxamide; 1417529-67-9; Imidazo[5,1-f][1,2,4]triazine-7-carboxylic Acid, 2-(2-Ethoxyphenyl)-1,4-dihydro-5-methyl-4-oxo-, Ethyl Ester. CAS No. 1417529-67-9. Molecular formula: C17H18N4O4. Mole weight: 342.36. |  |
| Vardenafil Impurity 11 | Vardenafil Impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18637-00-8. Molecular formula: C9H13ClN2O. Mole weight: 200.67. Catalog: APB18637008. | |
| Vardenafil Impurity 2 | An impurity of Vardenafil. Vardenafil is a PDE5 inhibitor used for the treatment of erectile dysfunction. Synonyms: Imidazo[5,?1-f]?[1,?2,?4]?triazine-7-carboxylic acid, 2-[2-ethoxy-5-[(4-ethyl-1-piperazinyl)?sulfonyl]?phenyl]?-1,?4-dihydro-5-methyl-4-oxo-, ethyl ester. CAS No. 1417529-69-1. Molecular formula: C23H30N6O6S. Mole weight: 518.6. | |
| Vardenafil Impurity 5 | An impurity of Vardenafil. Vardenafil is a PDE5 inhibitor used for the treatment of erectile dysfunction. Synonyms: N-(1-(3-(2-ethoxyphenyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)ethyl)butyramide. Molecular formula: C17H22N4O3. Mole weight: 330.39. | |
| Vardenafil N-Oxide | An impurity of Vardenafil. Vardenafil is a PDE5 inhibitor used for the treatment of erectile dysfunction. Synonyms: 4-((4-ethoxy-3-(5-methyl-4-oxo-7-propyl-1,4-dihydroimidazo[5,1-f][1,2,4]triazin-2-yl)phenyl)sulfonyl)-1-ethylpiperazine 1-oxide. Molecular formula: C23H32N6O5S. Mole weight: 504.61. | |
| Vardenafil Oxopiperazine | Vardenafil Oxopiperazine is a derivative of Vardenafil Dihydrochloride Salt, which is a PDE5 inhibitor used for the treatment of erectile dysfunction. Synonyms: 2-[2-Ethoxy-5-[(3-oxo-1-piperazinyl)sulfonyl]phenyl]-5-methyl-7-propyl-imidazo[5,1-f][1,2,4]triazin-4(1H)-one; 4-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4-ethoxyphenyl]sulfonyl]-piperazinone. CAS No. 448184-58-5. Molecular formula: C21H26N6O5S. Mole weight: 474.54. | |
| Vardenafil Related Compound (2-(2-Ethoxyphenyl)-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one) | An intermediate of Vardenafil. Vardenafil is a phosphodiesterase type 5 (PDE5) inhibitor used for the treatment of erectile dysfunction. Synonyms: 2-(2-Ethoxyphenyl)-5-methyl-7-propyl-imidazo[5,1-f][1,2,4]triazin-4(1H)-one. CAS No. 224789-21-3. Molecular formula: C17H20N4O2. Mole weight: 312.37. | |
| Vardenafil System Suitability | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Varenicline | Varenicline is a prescription medication used to treat smoking addiction. As a partial agonist it both reduces cravings for and decreases the pleasurable effects of cigarettes and other tobacco products. Through these mechanisms Varenicline can assist some patients to quit smoking. Synonyms: 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine; 6,7,8,9-tetrahydro-6,10-methano-6H-pyrazino(2,3-h)benzazepine; Champix; Chantix; (1R, 12S)-5, 8, 14-triazatetracyclo[10.3.1.02, 11.04, 9]hexadeca-2(11), 3, 5, 7, 9-pentaene; CP 526555; CP526555; CP-526555. Grades: > 98%. CAS No. 249296-44-4. Molecular formula: C13H13N3. Mole weight: 211.26. | |
| Varenicline | Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC 50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 526555. CAS No. 249296-44-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10019. | |
| Varenicline Carbamoyl 2,3,4-Tri-O-acetyl- β-D-glucuronide Methyl Ester | A protected metabolite of Varenicline. Group: Biochemicals. Alternative Names: 1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-carboxylate). Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Varenicline Carbamoyl 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester | Varenicline Carbamoyl 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester is one of Varenicline metabolites. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Synonyms: [(2S,3R,4S,5S,6S)-3,4,5-triacetyloxy-6-methoxycarbonyloxan-2-yl] 5, 8, 14-triazatetracyclo[10.3.1.02, 11.04, 9]hexadeca-2, 4, 6, 8, 10-pentaene-14-carboxylate; 1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-carboxylate)2,3,4-Tri-O-acetyl-β-D-glucopyranuronic Acid Methyl Ester; Methyl 2, 3, 4-tri-O-acetyl-1-O-[5, 8, 14-triazatetracyclo[10.3.1.02, 11.04, 9]hexadeca-2(11), 3, 5, 7, 9-pentaen-14-ylcarbonyl]-β-D-glucopyranuronate; β-D-Glucopyranuronic acid, 1-O-[(6,7,9,10-tetrahydro-6,10-methano-8H-azepino[4,5-g]quinoxalin-8-yl)carbonyl]-, methyl ester, 2,3,4-triacetate. Molecular formula: C27H29N3O11. Mole weight: 571.53. | |
| Varenicline Carbamoyl β-D-Glucuronide | A metabolite of Varenicline. Group: Biochemicals. Alternative Names: 1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-carboxylate). Grades: Highly Purified. CAS No. 535920-98-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Varenicline Carbamoyl β-D-Glucuronide-d4 | Varenicline Carbamoyl β-D-Glucuronide-d4. Group: Biochemicals. Alternative Names: 1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-carboxylate). Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C20H16D4N3O8. US Biological Life Sciences. | Worldwide |
| Varenicline Carbamoyl β-D-Glucuronide Methyl Ester | A protected metabolite of Varenicline. Group: Biochemicals. Alternative Names: 1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-carboxylate). Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Varenicline Carbamoyl β-D-Glucuronide Methyl Ester | Varenicline Carbamoyl β-D-Glucuronide Methyl Ester is one of Varenicline metabolites. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Synonyms: 1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-carboxylate) β-D-Glucopyranuronic Acid Methyl Ester; [(2S,3R,4S,5S,6S)-3,4,5-trihydroxy-6-methoxycarbonyloxan-2-yl] 5, 8, 14-triazatetracyclo[10.3.1.02, 11.04, 9]hexadeca-2, 4, 6, 8, 10-pentaene-14-carboxylate; Methyl 1-O-[5, 8, 14-triazatetracyclo[10.3.1.02, 11.04, 9]hexadeca-2(11), 3, 5, 7, 9-pentaen-14-ylcarbonyl]-β-D-glucopyranuronate; β-D-Glucopyranuronic acid, 1-O-[(6,7,9,10-tetrahydro-6,10-methano-8H-azepino[4,5-g]quinoxalin-8-yl)carbonyl]-, methyl ester. Molecular formula: C21H23N3O8. Mole weight: 445.42. | |
| Varenicline carbamoyl glucuronide | Varenicline carbamoyl glucuronide is a metabolite of Varenicline. Varenicline is a partial agonist of nicotinic receptor used for smoking cessation. It reduces both the desire for and the pleasure of cigarettes. Synonyms: Varenicline carbamoyl beta-D-glucuronide; Varenicline Carbamoyl-ß-D-glucuronide; Tolcapone 3-ß-D-Glucuronide; 1-(6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepin-8-carboxylate)β-D-Glucopyranuronic Acid; Metabolite M4. Grades: 98%. CAS No. 535920-98-0. Molecular formula: C20H21N3O8. Mole weight: 431.40. | |
| Varenicline dihydrochloride | Varenicline dihydrochloride is an α4β2 nicotinic acetylcholine receptor partial agonist. Varenicline is a prescription medication used for smoking cessation. Uses: Smoking cessation drug. Synonyms: 7,8,9,10-tetrahydro-6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine dihydrochloride; Varenicline 2HCl; DB-076707; FT-0701597. Grades: > 98%. CAS No. 866823-63-4. Molecular formula: C13H15Cl2N3. Mole weight: 284.18. | |
| Varenicline dihydrochloride | Varenicline (CP 526555-18) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC 50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 526555 dihydrochloride. CAS No. 866823-63-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10019A. | |
| Varenicline Hydrochloride | Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC 50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 526555 hydrochloride. CAS No. 230615-23-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10020. | |
| Varenicline Hydrochloride | Varenicline(CP 526555; Champix; Chantix) is a prescription medication used to treat smoking addiction. As a partial agonist it both reduces cravings for and decreases the pleasurable effects of cigarettes and other tobacco products. Through these mechanisms Varenicline(CP 526555; Champix; Chantix) can assist some patients to quit smoking. Synonyms: CP 526555 hydrochloride; CP526555 hydrochloride; CP-526555 hydrochloride; Champix hydrochloride; Chantix hydrochloride. Grades: >98%. CAS No. 230615-23-3. Molecular formula: C13H14ClN3. Mole weight: 247.72. | |
| Varenicline Impurity 1 | Varenicline Impurity 1 is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Synonyms: Ethanone, 2,2,2-trifluoro-1-(1,2,4,5-tetrahydro-7-nitro-1,5-methano-3H-3-benzazepin-3-yl)-; 1,5-Methano-1H-3-benzazepine, 2,3,4,5-tetrahydro-7-nitro-3-(trifluoroacetyl)-; 2,2,2-Trifluoro-1-(1,2,4,5-tetrahydro-7-nitro-1,5-methano-3H-3-benzazepin-3-yl)ethanone; (+/-)-2,2,2-trifluoro-1-(4-nitro-10-aza-tricyclo[6.3.1.02,7]dodeca-2(7),3,5-trien-10-yl)-ethanone; 7-nitro-3-(trifluoroacetyl)-2,3,4,5-tetrahydro-1H-1,5-methano-3-benzazepine; 2,2,2-trifluoro-1-(7-nitro-1,2,4,5-tetrahydro-3H-1,5-methanobenzo[d]azepin-3-yl)ethan-1-one. Grades: ≥90%. CAS No. 230615-53-9. Molecular formula: C13H11F3N2O3. Mole weight: 300.23. | |
| Varenicline Impurity 10 | Varenicline Impurity 10 is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Molecular formula: C14H15N3O. Mole weight: 241.29. | |
| Varenicline Impurity 11 DiHCl | Varenicline Impurity 11 DiHCl is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Synonyms: 1,5,6,7,8,9-Hexahydro-5,9-methanoimidazo[4,5-h][3]benzazepine, hydrochloride (1:2). Molecular formula: C12H13N3.2HCl. Mole weight: 272.17. | |
| Varenicline Impurity 12 | Cas No. 997-10-4. | |
| Varenicline Impurity 18 | Varenicline Impurity 18 is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Synonyms: 3-Hydroxy-7,8,9,10-tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline 1-oxide; 2-Oxo-2,6,7,8,9,10-hexahydro-1H-6,10-methanoazepino[4,5-g]quinoxaline 4-oxide; Hydroxyvarenicline N-Oxide. Grades: 98%. CAS No. 2306217-11-6. Molecular formula: C13H13N3O2. Mole weight: 243.26. | |
| Varenicline Impurity 5 | Varenicline Impurity 5 is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Synonyms: 1,5-Methano-1H-3-benzazepin-7-amine, 2,3,4,5-tetrahydro-8-nitro-; 2,3,4,5-Tetrahydro-8-nitro-1,5-methano-1H-3-benzazepin-7-amine; 8-Nitro-2,3,4,5-tetrahydro-1H-1,5-methanobenzo[d]azepin-7-amine. Grades: ≥95%. CAS No. 950781-87-0. Molecular formula: C11H13N3O2. Mole weight: 219.24. | |
| Varenicline Impurity 6 | Varenicline Impurity 6 is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Synonyms: 6,10-Methano-8H-pyrazino[2,3-h][3]benzazepine-8-carboxylic acid, 6,7,9,10-tetrahydro-; 6,7,9,10-Tetrahydro-6,10-methano-8H-pyrazino[2,3-h][3]benzazepine-8-carboxylic acid; 9,10-Dihydro-6H-6,10-methanoazepino[4,5-g]quinoxaline-8(7H)-carboxylic acid. Grades: ≥95%. CAS No. 1026685-55-1. Molecular formula: C14H13N3O2. Mole weight: 255.27. | |
| Varenicline Impurity 7 | Varenicline Impurity 7 is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Molecular formula: C13H13N3O. Mole weight: 227.26. | |
| Varenicline Impurity 8 | Varenicline Impurity 8 is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Synonyms: 2,3,4,5-tetrahydro-1H-1,5-methano-3-benzazepin-6,8-diamine. Grades: > 98%. CAS No. 950781-91-6. Molecular formula: C11H15N3. Mole weight: 189.26. | |
| Varenicline Impurity 9 | Varenicline Impurity 9 is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Molecular formula: C13H13F3N2O. Mole weight: 270.25. | |
| Varenicline impurity, N-Oxide | An impurity of Varenicline. Varenicline is a partial agonist of nicotinic receptor used for smoking cessation. It reduces both the desire for and the pleasure of cigarettes. Molecular formula: C13H12N3O. Mole weight: 226.26. | |
| Varenicline lactam | Varenicline lactam. Group: Biochemicals. Alternative Names: 6,8,9,10-Tetrahydro-6,10-methano-7H-pyrazino[2,3-h][3]benzazepin-7-one. Grades: Highly Purified. CAS No. 873302-30-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C13H11N3O. US Biological Life Sciences. | Worldwide |
| Varenicline lactam | Varenicline lactam. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6,8,9,10-Tetrahydro-. Product Category: Heterocyclic Organic Compound. CAS No. 873302-30-8. Molecular formula: C13H11N3O. Mole weight: 225.25. Purity: 0.96. IUPACName: 873302-30-8. Canonical SMILES: C1C2CNC(=O)C1C3=CC4=NC=CN=C4C=C23. Product ID: ACM873302308. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Varenicline Lactam | Varenicline Lactam is one of Varenicline metabolites. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. Uses: A metabolite of varenicline. Synonyms: 6,8,9,10-Tetrahydro-6,10-methano-7H-pyrazino[2,3-h][3]benzazepin-7-one; Varenicline Lactam Impurity; 6,10-Methano-7H-pyrazino[2,3-h][3]benzazepin-7-one, 6,8,9,10-tetrahydro-. Grades: ≥95%. CAS No. 873302-30-8. Molecular formula: C13H11N3O. Mole weight: 225.25. | |
| Varenicline Metadinitro Impurity | An impurity of Varenicline. Varenicline is a partial agonist of nicotinic receptor used for smoking cessation. It reduces both the desire for and the pleasure of cigarettes. Molecular formula: C14H11F3N2O5. Mole weight: 344.25. | |
| Varenicline N-glucoside | Varenicline N-glucoside is a metabolite of Varenicline. Varenicline is a partial agonist of nicotinic receptor used for smoking cessation. It reduces both the desire for and the pleasure of cigarettes. Synonyms: 8-b-D-Glucopyranosyl-7,8,9,10-tetrahydro-tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine. Grades: > 98%. CAS No. 873302-31-9. Molecular formula: C19H23N3O5. Mole weight: 373.40. | |
| Varenicline-N-oxide | Varenicline-N-oxide is one of Varenicline impurities. Varenicline is a nicotinic receptor partial agonist. It's a prescription drug used to treat cigarette addiction. CAS No. 2306217-12-7. Molecular formula: C13H13N3O. Mole weight: 227.26. | |
| Varenicline tartrate | 7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino[2,3-h][3]benzazepine tartrate. CAS No. 375815-87-5. Product ID: 8-05086. Molecular formula: C13H13N3 · C4H6O6. Mole weight: 361.35. |  |
| Varenicline Tartrate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyapi standardspharmaceutical toxicology. Alternative Names: CP 526555-18, Varenicline Tartrate,6,10-Methano-6H-pyrazino[2,3-h][3]benzazepine, 7,8,9,10-tetrahydro-, (2R,3R)-2,3-dihydroxybutanedioate (1:1). | |
| Varenicline Tartrate | Nicotinic α4 β2 acetylcholine receptor partial agonist. Aid in smoking cessation. Group: Biochemicals. Grades: Highly Purified. CAS No. 375815-87-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Varenicline Tartrate | Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC 50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 526555-18. CAS No. 375815-87-5. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10021. | |
| Varespladib | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Varespladib | Varespladib (LY315920) is a potent and selective group IIA, secretory phospholipase A 2 (sPLA 2 ) inhibitor with an IC 50 of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC 50 s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY315920. CAS No. 172732-68-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13402. | |
| Varespladib | Varespladib is a potent and selective inhibitor of secretory phospholipase A2 (sPLA2). The compound Varespladib inhibits both human and mouse sPLA2 group IIA, V, and X enzymes at low nM concentrations. Synonyms: LY315920; LY-315920; LY 315920; A-002; A002; A 002; Varespladib. Grades: >98%. CAS No. 172732-68-2. Molecular formula: C21H20N2O5. Mole weight: 380.39. | |
| Varespladib sodium | Varespladib sodium (LY315920 sodium) is a potent and selective group IIA, secretory phospholipase A 2 (sPLA 2 ) inhibitor with an IC 50 of 9 nM. Varespladib sodium exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC 50 s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY315920 sodium. CAS No. 172733-42-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13402A. | |
| Vargulin | Vargulin. Group: Biochemicals. Alternative Names: Cypridina luciferin; Vargula luciferin. Grades: Highly Purified. CAS No. 7273-34-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 20mg. Molecular Formula: C22H27N7O. US Biological Life Sciences. | Worldwide |
| Variacin | Variacin is a lanthionine-containing bacteriocin isolated from Kocuria varians. Synonyms: Gly-Ser-Gly-Val-Ile-Pro-Thr-Ile-Ser-His-Glu-Cys-His-Met-Asn-Ser-Phe-Gln-Phe-Val-Phe-Thr-Cys-Cys-Ser. | |
| Variamine blue b | Variamine blue b. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Variamine Blue B Base, A0647_SIGMA, CID77108, EINECS 222-652-7, SBB003144, N-(p-Methoxyphenyl)-p-phenylenediamine, 4-AMINO-4-METHOXYDIPHENYLAMINE HCl, 4-Amino-4-methoxydiphenylamine hydrochloride, N-(4-Methoxyphenyl)benzene-1,4-diamine monohydrochloride, N-(4-Methoxyphenyl)-1,4-benzenediamine hydrochloride, 1,4-Benzenediamine, N-(4-methoxyphenyl)-, monohydrochloride, 3566-44-7. Appearance: Grey-blue crystalline powder. CAS No. 3566-44-7. Molecular formula: C13H14N2O·HCl. Mole weight: 250.73. Purity: 98+%. IUPACName: 1-N-(4-methoxyphenyl)benzene-1,4-diamine hydrochloride. Canonical SMILES: COC1=CC=C(C=C1)NC2=CC=C(C=C2)N.Cl. Density: 1.178g/cm³. ECNumber: 222-652-7. Product ID: ACM3566447. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4-Amino-4'-methoxydiphenylamine hydrochloride. | |
| Variamycin | Variamycin is a glycoside antibiotic originally isolated from Streptomyces olivovariabilis 6604-9. It has the effect of resisting gram-positive bacteria, fungi and tumors. Synonyms: Variamitsin; Varamycin; NSC 269146; Antibiotic 6604-9A; 3(C)-Demethyl-4(C)-O-methylmithramycin. CAS No. 12677-11-1. Molecular formula: C52H76O24. Mole weight: 1085.14. | |
| Varioxepine A | Varioxepine A is a fungal metabolite produced by the strain of P. variotii. It is active against the plant pathogenic fungus F. graminearum (MIC = 4 μg/ml). Synonyms: Varioxepine A; 1623451-72-8; (16aR)3R,4-dihydro-4,4-dimethyl-10-(1-methylethyl)-7S-(phenylmethyl)-3,5aS-epoxy-2H,5aH,7H-[1,4]dioxepino[2,3-e]oxepino[2,3-d]pyrazino[1,2-a]pyrimidin-8(9H)-one; (1S, 3S, 15R, 18R)-3-benzyl-19, 19-dimethyl-6-propan-2-yl-10, 16, 20, 21-tetraoxa-2, 5, 8-triazapentacyclo[16.2.1.01, 15.02, 7.09, 15]henicosa-6, 8, 11, 13-tetraen-4-one; HY-N10256; CS-0371780. Grades: >95% by HPLC. CAS No. 1623451-72-8. Molecular formula: C26H29N3O5. Mole weight: 463.52. | |
| varlilumab | A human agonistic monoclonal antibody (MoAb) specific for CD27, with potential immunostimulating and antineoplastic activity. Synonyms: CDX 1127; CDX-1127; CDX1127; UNII-0125DUV5XC. CAS No. 1393344-72-3. Molecular formula: C6486H9992N1740O2022S42. | |
| Varlilumab | Varlilumab (CDX-1127) is a first-in-class human IgG1 anti- CD27 monoclonal antibody. Varlilumab has an anti-tumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CDX-1127. CAS No. 1393344-72-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99057. | |
| Varlilumab (anti-CD27) | Varlilumab (anti-CD27) is a first-in-class human IgG1 anti- CD27 monoclonal antibody. Varlilumab has an anti-tumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1393344-72-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99057A. | |
| Varlitinib | Varlitinib (ASLAN001) is a potent, reversible, small molecule pan- EGFR inhibitor with IC 50 s of 7, 2, 4 nM for HER1, HER2 and HER4, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASLAN001; ARRY-334543. CAS No. 845272-21-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10530. | |
| Varlitinib | Varlitinib, also known as ARRY-543, is an orally bioavailable inhibitor of the epidermal growth factor receptor family with potential antineoplastic activity. Varlitinib selectively and reversibly binds to both EGFR (ErbB-1) and Her-2/neu (ErbB-2) and prevents their phosphorylation and activation, which may result in inhibition of the associated signal transduction pathways, inhibition of cellular proliferation and cell death. EGFR and Her-2 play important roles in cell proliferation and differentiation and are upregulated in various human tumor cell types. Due to the dual inhibition of both EGFR and Her-2, this agent may be therapeutically more effective than agents that inhibit EGFR or Her-2 alone. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). (last updated ). Synonyms: code name: AR 00334543; ARRY-334543; ARRY334543; ARRY-543; ARRY543; ARRY 543. Grades: 0.99. CAS No. 845272-21-1. Molecular formula: C22H19ClN6O2S. Mole weight: 466.944. | |
| Varv peptide A | Varv peptide A is a macrocyclic polypeptide isolated from Viola arvensis. Synonyms: Gly-Leu-Pro-Val-Cys-Gly-Glu-Thr-Cys-Val-Gly-Gly-Thr-Cys-Asn-Thr-Pro-Gly-Cys-Ser-Cys-Ser-Trp-Pro-Val-Cys-Thr-Arg-Asn. | |
| Varv peptide B | Varv peptide B is a macrocyclic polypeptide isolated from Viola arvensis. Synonyms: Gly-Leu-Pro-Val-Cys-Gly-Glu-Thr-Cys-Phe-Gly-Gly-Thr-Cys-Asn-Thr-Pro-Gly-Cys-Ser-Cys-Asp-Pro-Trp-Pro-Met-Cys-Ser-Arg-Asn. | |
| Varv peptide C | Varv peptide C is a macrocyclic polypeptide isolated from Viola arvensis. Synonyms: Gly-Val-Pro-Ile-Cys-Gly-Glu-Thr-Cys-Val-Gly-Gly-Thr-Cys-Asn-Thr-Pro-Gly-Cys-Ser-Cys-Ser-Trp-Pro-Val-Cys-Thr-Arg-Asn. | |
| Varv peptide D | Varv peptide D is a macrocyclic polypeptide isolated from Viola arvensis. Synonyms: Gly-Leu-Pro-Ile-Cys-Gly-Glu-Thr-Cys-Val-Gly-Gly-Ser-Cys-Asn-Thr-Pro-Gly-Cys-Ser-Cys-Ser-Trp-Pro-Val-Cys-Thr-Arg-Asn. | |
| Varv peptide E | Varv peptide E is a macrocyclic polypeptide isolated from Viola arvensis. Synonyms: Gly-Leu-Pro-Ile-Cys-Gly-Glu-Thr-Cys-Val-Gly-Gly-Thr-Cys-Asn-Thr-Pro-Gly-Cys-Ser-Cys-Ser-Trp-Pro-Val-Cys-Thr-Arg-Asn. | |
| Varv peptide F | Varv peptide F is a macrocyclic polypeptide isolated from Viola arvensis. Synonyms: Gly-Val-Pro-Ile-Cys-Gly-Glu-Thr-Cys-Thr-Leu-Gly-Thr-Cys-Tyr-Thr-Ala-Gly-Cys-Ser-Cys-Ser-Trp-Pro-Val-Cys-Thr-Arg-Asn. | |
| Varv peptide G | Varv peptide G is a macrocyclic polypeptide isolated from Viola arvensis. Synonyms: Gly-Val-Pro-Val-Cys-Gly-Glu-Thr-Cys-Phe-Gly-Gly-Thr-Cys-Asn-Thr-Pro-Gly-Cys-Ser-Cys-Asp-Pro-Trp-Pro-Val-Cys-Ser-Arg-Asn. | |
| Varv peptide H | Varv peptide H is a macrocyclic polypeptide isolated from Viola arvensis. Synonyms: Gly-Leu-Pro-Val-Cys-Gly-Glu-Thr-Cys-Phe-Gly-Gly-Thr-Cys-Asn-Thr-Pro-Gly-Cys-Ser-Cys-Glu-Thr-Trp-Pro-Val-Cys-Ser-Arg-Asn. | |
| VAS2870 | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| VAS2870 | VAS2870 is a cell-permeable and selective inhibitor of the NADPH oxidases. It was shown to enhance apoptosis induced by a physiological stimulus, such as TGF-β, and inhibit either autocrine or serum-dependent cell growth in several human HCC cell lines. Synonyms: VAS-2870; VAS 2870; 2-(3-Benzyltriazolo[4,5-d]pyrimidin-7-yl)sulfanyl-1,3-benzoxazole. Grades: ≥98%. CAS No. 722456-31-7. Molecular formula: C18H12N6OS. Mole weight: 360.4. | |
| VAS3947 | VAS3947 is a selective inhibitor of NADPH oxidase activity in low micromolar concentrations, interfering neither with ROS detection nor with XOD or eNOS activities. VAS3947 induces apoptosis in AML cells independently of its anti-NOX activity. VAS3947 thiol alkylates cysteine residues of glutathione (GSH), while also interacting with proteins. Remarkably, VAS3947 decreased detectable GSH in the MV-4-11 cell line, thereby suggesting possible oxidative stress induction. Overall, VAS3947 induces apoptosis independently of anti-NOX activity, via UPR activation, mainly due to aggregation and misfolding of proteins. Uses: Designed for use in research and industrial production. Additional or Alternative Names: VA-S3947; VA S3947; VAS3947. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 869853-70-3. Molecular formula: C14H10N6OS. Mole weight: 310.34. Purity: >98%. IUPACName: 3-Benzyl-7-(2-oxazolyl)thio-1,2,3-triazolo[4,5-d]pyrimidine. Canonical SMILES: C12=NC=NC(SC3=NC=CO3)=C1N=NN2CC4=CC=CC=C4. Product ID: ACM869853703. Alfa Chemistry ISO 9001:2015 Certified. | |
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