A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody. Veltuzumab has low EC 50 value of 0.08-0.09 μg/mL in the Daudi cell line. Veltuzumab can be used for the research of cancer including non-Hodgkin lymphoma (NHL) [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: IMMU-106; hA20. CAS No. 728917-18-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99224.
Veltuzumab
Veltuzumab is a humanized anti-CD20 monoclonal antibody. Veltuzumab has been investigated for the treatment of non-Hodgkin's lymphoma. Synonyms: IMMU-106; hA20. CAS No. 728917-18-8.
Velufenacin
Velufenacin is a muscarinic receptor antagonist [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DA-8010. CAS No. 1648737-78-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109196.
Velusetrag
Velusetrag (TD-5108) is an orally active, potent and selective agonist of serotonin 5-HT 4 receptor (5-HT4R) , with a pK i of 7.7. Velusetrag exhibits no affinity (K i >10 μM) for 5-HT 2A and 5-HT 2B receptors. Velusetrag can be used for the research of gastrointestinal diseases and Parkinson's disease [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TD-5108. CAS No. 866933-46-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10457.
Velusetrag
Velusetrag is a selective, 5-HT4receptor agonist. Phase II clinical trials for the treatment of gastroparesis are on-going. Clnical trials for Alzheimer's disease and Constipation were discontinued. Uses: Gastroparesis. Synonyms: UNII-J4VNV64ARB; TD-5108; TD5108; TD 5108; J4VNV64ARB; GTPL8425;N-[(1R,5S)-8-[(2R)-2-hydroxy-3-[methyl(methylsulfonyl)amino]propyl]-8-azabicyclo[3.2.1]octan-3-yl]-2-oxo-1-propan-2-ylquinoline-3-carboxamide. Grades: 98%. CAS No. 866933-46-2. Molecular formula: C25H36N4O5S. Mole weight: 504.65.
Velusetrag hydrochloride
Velusetrag (TD-5108) hydrochloride is an orally active, potent and selective agonist of serotonin 5-HT 4 receptor (5-HT 4 R) , with a pK i of 7.7. Velusetrag hydrochloride exhibits no affinity (K i >10 μM) for 5-HT 2A and 5-HT 2B receptors. Velusetrag hydrochloride can be used for the research of gastrointestinal diseases and Parkinson's disease [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TD-5108 hydrochloride. CAS No. 866933-51-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-10457A.
Velutin.
Velutin. Group: Biochemicals. Grades: Plant Grade. CAS No. 25739-41-7. Pack Sizes: 20mg. Molecular Formula: C17H14O6, Molecular Weight: 314.29. US Biological Life Sciences.
Vemircopan (ALXN2050) is an orally active complement factor D inhibitor. Vemircopan is promising for research of paroxysmal nocturnal hemoglobinuria [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALXN2050; ACH 0145228; ACH-5228. CAS No. 2086178-00-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139588.
Vemurafenib
Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC 50 s of 31 and 48 nM for RAF V600E and c-RAF-1, respectively [1] [4]. Vemurafenib induces cell autophagy [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PLX4032; RG7204; RO5185426. CAS No. 918504-65-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-12057.
Vemurafenib
Vemurafenib is a potent and selective inhibitor of B-RafV600E with IC50 of 13 nM, equally potent to c-Raf-1(Y340D and Y341D mutations), 10-fold selectivity than wild-type B-Raf. Synonyms: PLX4032; PLX 4032; PLX-4032; RG7204 ; RG7204 ; RG 7204 ; RO5185426; RO 5185426 RO5185426 Vemurafenib; Brand name: Zelboraf. Grades: >98%. CAS No. 918504-65-1. Molecular formula: C23H18ClF2N3O3S. Mole weight: 489.92.
Vemurafenib-Analog
BRAF inhibitor is a potent BRAF inhibitor. Synonyms: 2-Propanesulfonamide, N-[2,4-difluoro-3-[[5-(3-pyridinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]phenyl]-. Grades: >98%. CAS No. 918505-61-0. Molecular formula: C22H18F2N4O3S. Mole weight: 456.47.
Vemurafenib, Free Base (PLX4032)
Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600. Group: Biochemicals. Alternative Names: N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide; PLX4032; RG7204; RO51-85426; Zelboraf. Grades: Highly Purified. CAS No. 918504-65-1. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences.
Worldwide
Venadaparib Impurity 33
Venadaparib Impurity 33. Uses: For analytical and research use. Group: Impurity standards. CAS No. 18584-75-3. Molecular formula: C10H10N4O2. Mole weight: 218.22. Catalog: APB18584753.
Venadaparib Impurity 40
Venadaparib Impurity 40. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1681017-95-7. Molecular formula: C24H25FN4O2. Mole weight: 420.49. Catalog: APB1681017957.
Venadaparib Impurity 6
Venadaparib Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 107558-48-5. Molecular formula: C14H11N3O. Mole weight: 237.26. Catalog: APB107558485.
venetoclax
Venetoclax is a small-molecule inhibitor that has high selectivity for Bcl-2 (Ki < 0.01 nM in cell-free assays) over Mcl-1. It suppresses anti-apoptotic Bcl-2, a protein commonly overexpressed in cancer cells, to induce programmed death of CLL cells. Venetoclax is used as a second-line treatment of chronic lymphocytic leukemia (CLL). Uses: The treatment of chronic lymphocytic leukemia (cll). Synonyms: ABT199; ABT-199; ABT 199; GDC0199; GDC0199; GDC 0199; RG7601; RG7601; RG 7601. Venetoclax. CAS No. 1257044-40-8. Molecular formula: C45H50ClN7O7S. Mole weight: 868.44.
Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a K i of less than 0.01 nM. Venetoclax induces autophagy [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-199; GDC-0199; RG7601. CAS No. 1257044-40-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-15531.
Venetoclax
Venetoclax. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide. CAS No. 1257044-40-8. Molecular formula: C45H50ClN7O7S. Mole weight: 868.44. Catalog: APB1257044408.
Venetoclax Impurity 10
Venetoclax Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine-1-carboxylate. CAS No. 1228780-71-9. Molecular formula: C24H35ClN2O2. Mole weight: 419.00. Catalog: APB1228780719.
Venetoclax Impurity 17
Venetoclax Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate. CAS No. 1235865-75-4. Molecular formula: C15H11FN2O3. Mole weight: 286.26. Catalog: APB1235865754.
Venetoclax Impurity 6
Venetoclax Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoate. CAS No. 1235865-76-5. Molecular formula: C34H37ClN4O3. Mole weight: 585.14. Catalog: APB1235865765.
Venetoclax Impurity 7
Venetoclax Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid. CAS No. 1235865-77-6. Molecular formula: C33H35ClN4O3. Mole weight: 571.11. Catalog: APB1235865776.
Venetoclax Impurity 8
Venetoclax Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-carbaldehyde. CAS No. 1228837-05-5. Molecular formula: C15H17ClO. Mole weight: 248.75. Catalog: APB1228837055.
Venetoclax Impurity 9
Venetoclax Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methanol. CAS No. 1228780-51-5. Molecular formula: C15H19ClO. Mole weight: 250.76. Catalog: APB1228780515.
Venlafaxine
Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Wy 45030. CAS No. 93413-69-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0196.
Venlafaxine cyclic impurity
Venlafaxine cyclic impurity. Group: Biochemicals. Alternative Names: 5-(4-Methoxyphenyl)-3-methyl-1-oxa-3-azaspiro[5.5]undecane. Grades: Highly Purified. CAS No. 93413-70-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C17H25NO2. US Biological Life Sciences.
Worldwide
Venlafaxine-d6
Venlafaxine-d 6 is the deuterium labeled Venlafaxine. Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1020720-02-8. Pack Sizes: 5 mg. Product ID: HY-B0196S.
Venlafaxine-d6 hydrochloride
Venlafaxine-d 6 (hydrochloride) is the deuterium labeled Venlafaxine hydrochloride. Venlafaxine hydrochloride (Wy 45030 hydrochloride) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: Wy 45030-d6 hydrochloride. CAS No. 1062606-12-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-B0196AS1.
Venlafaxine EP Impurity G
Venlafaxine EP Impurity G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1076199-92-2. Molecular formula: C17H27NO. Mole weight: 261.41. Catalog: APB1076199922.
Venlafaxine EP Impurity H
Venlafaxine EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1329795-88-1. Molecular formula: C24H33NO3. Mole weight: 383.53. Catalog: APB1329795881.
Venlafaxine hydrochloride
Venlafaxine hydrochloride (Wy 45030 hydrochloride) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Wy 45030 hydrochloride. CAS No. 99300-78-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0196A.
Venlafaxine hydrochloride
Venlafaxine hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 99300-78-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Venlafaxine hydrochloride (Standard)
Venlafaxine (hydrochloride) (Standard) is the analytical standard of Venlafaxine (hydrochloride). This product is intended for research and analytical applications. Venlafaxine hydrochloride (Wy 45030 hydrochloride) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Wy 45030 hydrochloride (Standard). CAS No. 99300-78-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0196AR.
Venlafaxine Hydroxyl Methyl Impurity
An impurity of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Molecular formula: C18H29NO3 HCl. Mole weight: 343.9.
Venlafaxine Hydroxy Nitrile Impurity
Venlafaxine Hydroxy Nitrile Impurity is an intermediate in the synthesis of N,O-Didesmethylvenlafaxine, which is a metabolite of Venlafaxine. Synonyms: 1-(Cyano-(4-methoxyphenyl)methyl)cyclohexanol; α-(1-Hydroxycyclohexyl)-4-methoxy-benzeneacetonitrile; α-(p-Methoxyphenyl)-α-(1-hydroxycyclohexyl)acetonitrile; (4-Methoxyphenyl)-(1-hydroxycyclohex-1-yl)acetonitrile; 1-[Cyano(4-methoxyphenyl)methyl]cyclohexanol; 1-[Cyano(p-methoxyphenyl)methyl]cyclohexanol. CAS No. 93413-76-4. Molecular formula: C15H19NO2. Mole weight: 245.32.
Venlafaxine Impurity 1
An impurity of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Molecular formula: C15H23NO. Mole weight: 233.36.
Venlafaxine Impurity 40
Venlafaxine Impurity 40. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1062606-12-5. Molecular formula: C17H22D6ClNO2. Mole weight: 319.9. Catalog: APB1062606125.
Venlafaxine Impurity B HCl
Cas No. 2174001-92-2.
Venlafaxine Impurity C HCl
Cas No. 130198-05-9.
Venlafaxine Impurity D
Cas No. 93413-90-2.
Venlafaxine Impurity E HCl
Cas No. 93413-56-0.
Venlafaxine Impurity F HCl
Cas No. 93413-79-7.
Venlafaxine Impurity G HCl
Cas No. 2108968-20-1.
Venlafaxine Impurity H
Cas No. 1329795-88-1.
Venlafaxine N-Dimer
Venlafaxine N-Dimer is a metabolite of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Synonyms: O-Desmethyl Venlafaxine N-Dimer; 4-[2- (Dimethylamino) -1- (1-hydroxycyclohexyl) ethyl]-2-[[[2- (1-hydroxycyclohexyl) -2- (4-hydroxyphenyl) ethyl]methylamino]methyl]phenol. CAS No. 1187545-61-4. Molecular formula: C32H48N2O4. Mole weight: 524.75.
Venlafaxine N-Oxide
Venlafaxine N-Oxide is a prodrug. Group: Biochemicals. Alternative Names: 1-[2- (Dimethyloxidoamino) -1- (4-methoxyphenyl) ethyl]cyclohexanol. Grades: Highly Purified. CAS No. 1094598-37-4. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Venlafaxine N-Oxide Impurity
An impurity of Venlafaxine. Venlafaxine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that is used as an antidepressant. According to different doses, it effects on serotonergic transmission, noradrenergic systems and dopaminergic neurotransmission. Venlafaxine is commonly used to treat depression, general anxiety disorder, social phobia, panic disorder, and vasomotor symptoms. Synonyms: Venlafaxine N-Oxide Impurity; 2-(1-Hydroxycyclohexyl)-2-(4-hydroxyphenyl)-N,N-dimethylethanamine oxide; SCHEMBL1699440; D,L-O-Desmethyl Venlafaxine N-Oxide. CAS No. 1021933-95-8. Molecular formula: C16H25NO3. Mole weight: 279.38.
Venlafaxine Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
venombin A
A somewhat thrombin-like enzyme from venoms of snakes of the viper/rattlesnake group. Species variants of the enzyme include ancrod from Agkistrodon rhodostoma (Malayan pit viper) (formerly EC 3.4.21.28), batroxobin from Bothrops atrox (South American pit viper) (formerly EC 3.4.21.29) and crotalase from Crotalus adamanteus (Eastern diamondback rattlesnake) (formerly EC 3.4.21.30). In peptidase family S1 (trypsin family). Does not require activation by Ca2+. Group: Enzymes. Synonyms: α-fibrinogenase; habutobin; zinc metalloproteinase Cbfib1.1; zinc metalloproteinase Cbfib1.2; zinc metalloproteinase Cbfib2; ancrod; (see also Comments). Enzyme Commission Number: EC 3.4.21.74. CAS No. 146240-35-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4166; venombin A; EC 3.4.21.74; 146240-35-9; α-fibrinogenase; habutobin; zinc metalloproteinase Cbfib1.1; zinc metalloproteinase Cbfib1.2; zinc metalloproteinase Cbfib2; ancrod; (see also Comments). Cat No: EXWM-4166.
venombin AB
From the venom of the Gaboon viper Bitis gabonica. Activates Factor XIII. Not inhibited by antithrombin III/heparin or hirudin, unlike EC 3.4.21.5, thrombin. Group: Enzymes. Synonyms: gabonase; okinaxobin II; Bitis gabonica venom serine proteinase; afa?cytin. Enzyme Commission Number: EC 3.4.21.55. CAS No. 104003-74-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4147; venombin AB; EC 3.4.21.55; 104003-74-9; gabonase; okinaxobin II; Bitis gabonica venom serine proteinase; afa?cytin. Cat No: EXWM-4147.
venom exonuclease
Preference for single-stranded substrate. Group: Enzymes. Synonyms: venom phosphodiesterase. Enzyme Commission Number: EC 3.1.15.1. CAS No. 9025-82-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3542; venom exonuclease; EC 3.1.15.1; 9025-82-5; venom phosphodiesterase. Cat No: EXWM-3542.
Venturicidin A
The macrolide antibiotic isolated from a streptomyces sp. It is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. It is originally isolated as an antifungal agent. Synonyms: Aabomycin A1. Grades: >95% by HPLC. CAS No. 33538-71-5. Molecular formula: C41H67NO11. Mole weight: 749.97.
Venturicidin A (Aabomycin A1)
The macrolide antibiotic Venturicidin A, isolated from a Streptomyces sp., is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. Originally isolated as an antifungal agent. Group: Biochemicals. Alternative Names: Aabomycin A1. Grades: Highly Purified. CAS No. 33538-71-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Venturicidin B
The macrolide antibiotic isolated from a streptomyces sp. It is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. It is originally isolated as an antifungal agent. Synonyms: Aabomycin A2; (1R,2E,7R,8E,10R,12R,13S,17R)-7-[(2R,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-17-hydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4,6-dimethyl-7-oxononan-2-yl]-2,10,12,20-tetramethyl-14,21-dioxabicyclo[15.3.1]henicosa-2,8,19-trien-15-one. Grades: >95% by HPLC. CAS No. 33538-72-6. Molecular formula: C40H66O10. Mole weight: 706.94.
Venturicidin B (Aabomycin A2)
The macrolide antibiotic Venturicidin B, isolated from a Streptomyces sp., is a potent inhibitor of mitochondrial ATP synthase complex acting on the F0 membrane sector. Originally isolated as an antifungal agent. Group: Biochemicals. Alternative Names: Aabomycin A2. Grades: Highly Purified. CAS No. 33538-72-6. Pack Sizes: 250ug. US Biological Life Sciences.
Worldwide
Vepafestinib
Vepafestinib is a tyrosine kinase inhibitor and antineoplastic. Synonyms: vepafestinibum; 7H-Pyrrolo[2,3-d]pyrimidine-5-carboxamide, 4-amino-N-[4-(methoxymethyl)phenyl]-7-(1-methylcyclopropyl)-6-[3-(4-morpholinyl)-1-propyn-1-yl]-. Grades: >98%. CAS No. 2129515-96-2. Molecular formula: C26H30N6O3. Mole weight: 474.6.
Vepdegestrant
Vepdegestrant (ARV-471) is an orally active PROTAC estrogen receptor degrader against breast cancer. Vepdegestrant is a hetero-bifunctional molecule that facilitates the interactions between estrogen receptor alpha and an intracellular E3 ligase complex. Vepdegestrant leads to the ubiquitylation and subsequent degradation of estrogen receptors via the proteasome. Vepdegestrant robustly degrades ER in ER-positive breast cancer cell lines with a half-maximal degradation concentration ( DC 50 ) of about 2 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ARV-471. CAS No. 2229711-68-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138642.
VER 155008
VER 155008. Group: Biochemicals. Grades: Purified. CAS No. 1134156-31-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
VER-155008
VER-155008 is an adenosine-derived inhibitor of heat shock protein 70 (Hsp70; IC50 = 0.5 μM) that is selective over Hsp90. It targets the nucleotide-binding domain (NBD) of Hsp70 and similarly binds the NBDs of Hsp70 cognates Hsc70 (Ki = 10 μM) and glucose-regulated protein 78 (Grp78; KD = 80 nM). VER-155008 inhibits the proliferation of human breast and colon cancer cell lines, inducing apoptosis or caspase-independent cell death. It induces the proteasome-dependent degradation of Hsp90 client proteins and potentiates the apoptotic activity of Hsp90 inhibitors. VER-15508 also triggers paraptosis in anaplastic thyroid carcinoma cells. Synonyms: 8-(3,4-Dichlorobenzyl)amino-5'-O-(4-cyanobenzyl)adenosine; C07; VER 155008; VER155008; 5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-Adenosine; 4-((((2R,3S,4R,5R)-5-(6-amino-8-(3,4-dichlorobenzylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)benzonitrile. Grades: ≥95%. CAS No. 1134156-31-2. Molecular formula: C25H23Cl2N7O4. Mole weight: 556.40.
VER-250840 is a novel oral Chk1 inhibitor (IC50 < 1 nM; Kd = 69 pM) with an antiproliferative activity against tumor cells. Uses: Potential antitumor drug. Synonyms: VER250840; VER 250840.
VER-49009
VER-49009 a protein 90 (HSP90) inhibitor(IC50= 47 nM). Uses: A heat shock protein 90 (hsp90) inhibitor. Synonyms: VER49009; VER 49009; VER-49009; (5Z)-5-(3-chloro-4-hydroxy-6-oxocyclohexa-2,4-dien-1-ylidene)-N-ethyl-4-(4-methoxyphenyl)-1,2-dihydropyrazole-3-carboxamide;CCT 129397; CCT129397; CCT-1293975-(5-Chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-1H-pyrazole-3-carboxamide. Grades: ≥98%. CAS No. 558640-51-0. Molecular formula: C19H18ClN3O4. Mole weight: 387.82.
VER-50589
VER-50589 is a potent Hsp90 inhibitor with IC50 of 21 nM for Hsp90&beta. Synonyms: NSC 606170; NSC606170; NSC-606170; Ro 24-2027/000; VER-50589; VER 50589; VER50589. Grades: >98%. CAS No. 747413-08-7. Molecular formula: C19H17ClN2O5. Mole weight: 388.80.
Veraguensin
Veraguensin. Group: Biochemicals. Grades: Plant Grade. CAS No. 19950-55-1. Pack Sizes: 10mg. Molecular Formula: C22H28O5, Molecular Weight: 372.46. US Biological Life Sciences.
Worldwide
Veralipride
Veralipride is a D2 receptor antagonist. It is an alternative antidopaminergic treatment for menopausal symptoms. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Veralipride; LIR166. CAS No. 66644-81-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101797.
Veralipride
Veralipride is a D2 receptor antagonist in the hypothalamic system and has a half-life of approximately 12 hours. Veralipride is highly active on the neurotransmitters, producing both a weak blockade of the central postsynaptic dopaminergic receptors and particularly a strong blockade of the dopamine receptors in the hypothalamic nuclei. Synonyms: Benzamide, 5-(aminosulfonyl)-2,3-dimethoxy-N-[[1-(2-propen-1-yl)-2-pyrrolidinyl]methyl]-; 5-(Aminosulfonyl)-2,3-dimethoxy-N-[[1-(2-propen-1-yl)-2-pyrrolidinyl]methyl]benzamide; Benzamide, 5-(aminosulfonyl)-2,3-dimethoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-; (±)-Veralipride; Agreal; LIR 1660; LIR-1660; LIR1660. Grades: ≥95%. CAS No. 66644-81-3. Molecular formula: C17H25N3O5S. Mole weight: 383.46.
Verapamil
Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. Verapamil also inhibits CYP3A4. Verapamil has the potential for high blood pressure, heart arrhythmias and angina research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (±)-Verapamil; CP-16533-1. CAS No. 52-53-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-14275.