A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Verticillin A
Verticillin A is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Synonyms: (6S,6'S)-19,19'-Dideoxy-6,6'-dihydroxychetocin. CAS No. 32164-16-2. Molecular formula: C30H28N6O6S4. Mole weight: 696.84.
Verticillin B
Verticillin B is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Synonyms: (6S,6'S)-19-Deoxy-6,6'-dihydroxychetocin. CAS No. 52212-86-9. Molecular formula: C30H28N6O7S4. Mole weight: 712.84.
Verticillin C
Verticillin C is originally isolated from Verticillium sp. Tm-759. It has the effect of anti-gram-positive bacteria, mycobacterium and protozoa, and has the inhibitory effect on the cancer of Ascites. Synonyms: Verticillin C. Grades: 95%. CAS No. 51798-48-2. Molecular formula: C30H28N6O7S5. Mole weight: 744.90.
Vertimycin
It is a cyclopentane derivative of antibiotic produced by the strain of Streptoverticillium sp. JA 4498. It has anti-gram-positive bacteria and fungal effects. It has weak effect on Ehrlich ascites cancer cells in vitro. Synonyms: Cyclopentanone, 2-(2-hydroxyethoxy)-5-(hydroxymethyl)-; 1-Ethylenodiolo-3-methylolo-cyclopentanone-2; 1-(Aethylendiol-1,2)-methylol-3-cyclopentanon-2. CAS No. 14477-60-2. Molecular formula: C8H14O4. Mole weight: 174.19.
Vertisporin
It is an antibiotic produced by the strain of Verticimonosporium diffractum TM-2098 and TM-2492. It has the effect against a few fungal. It is cytotoxic to HeLa cells with ED50 of 0.001 μg/mL. Synonyms: Spiro[4H-3a, 22-(epoxyethano)-10, 12-methano-17H, 18H-furo[2', 3':10, 11][1, 6]dioxacyclohexadecino[3, 4-d][1]benzopyran-11(12H), 2'-oxirane]-8, 20(5H, 22aH)-dione, 2, 3, 10, 10a, 13a, 16-hexahydro-2, 3-dihydroxy-10a, 15-dimethyl-, (2R, 2'S, 3R, 3aR, 6Z, 10R, 10aS, 12R, 13aR, 17aR, 21E, 21bR)-. CAS No. 57100-32-0. Molecular formula: C29H36O10. Mole weight: 544.59.
Verubecestat
Verubecestat, an iminothiadiazine dioxide compound, is an oral BACE1 inhibitor originated by Merck & Co. It can bind significantly to β-secretase. Verubecestat has the potent effect to treat Alzheimer's disease and is currently in Phase III clinical trials. Uses: Alzheimer's disease. Synonyms: N-[3-[(5R)-3-amino-2,5-dimethyl-1,1-dioxo-6H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoropyridine-2-carboxamide; J1I0P6WT7T; Verubecestat; UNII-J1I0P6WT7T; J1I0P6WT7T; 1286770-55-5; Verubecestat [USAN]; Verubecestat (USAN/INN); GTPL8699; CHEMBL3301601; SCHEMBL10328722; SCHEMBL17507398; BDBM143220; example 25 (US8940748); SCH-900931; D10739; US8940748, 25; 2-Pyridinecarboxamide, N-(3-((5R)-3-amino-5,6-dihydro-2,5-dimethyl-1,1-dioxido-2H-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoro-; N-(3-((5R)-3-amino-2,5-dimethyl-1,1-dioxo-1,2,5,6-tetrahydro-1lambda6,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropyridine-2-carboxamide; N-(3-((5R)-3-amino-2,5-dimethyl-1,1-dioxo-5,6-dihydro-2H-1lambda6,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropyridine-2-carboxamide; N-[3-[(5R)-3-amino-2,5-dimethyl-1,1-dioxo-6H-1,2,4-thiadiazin-5-yl]-4-fluorophenyl]-5-fluoropyridine-2-carboxamide. Grades: 98%. CAS No. 1286770-55-5. Molecular formula: C17H17F2N5O3S. Mole weight: 409.41.
Verubecestat
Verubecestat (MK-8931) is an orally active, high-affinity BACE1 and BACE2 inhibitor with K i values of 2.2 nM and 0.38 nM. Verubecestat effectively reduces Aβ40 and has the potential for Alzheimer's Disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-8931. CAS No. 1286770-55-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16759.
Verubecestat TFA
Verubecestat, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MK-8931; MK 8931; MK8931; MK-8931-009; SCH 900931; SCH-900931; SCH900931; Verubecestat TFA. Product Category: Inhibitors. Appearance: White to off-white solid powder. CAS No. 2095432-65-6. Molecular formula: C19H18F5N5O5S. Mole weight: 523.44. Purity: >98%. IUPACName: (R)-N-(3-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2H-1,2,4-thiadiazin-5-yl)-4-fluorophenyl)-5-fluoropicolinamide trifluoroacetic acid. Canonical SMILES: O=C(NC1=CC=C(F)C([C@@](C2)(C)N=C(N)N(C)S2(=O)=O)=C1)C3=NC=C(F)C=C3.O=C(O)C(F)(F)F. Product ID: ACM2095432656. Alfa Chemistry ISO 9001:2015 Certified.
Verubulin
Verubulin, also known as MPC-6827, is quinazoline derivative with potential dual antineoplastic activities. Verubulin hydrochloride binds to and inhibits tubulin polymerization and interrupts microtubule formation, resulting in disruption of mitotic spindle assembly, cell cycle arrest in the G2/M phase, and cell death. This agent is not a substrate for several subtypes of multidrug resistance ABC transporters, such as P-glycoprotein, multidrug resistance-associated protein 1 (MRP1), and breast cancer resistance protein 1 (BCRP1); therefore, it may be useful for treating multidrug resistant (MDR) tumors that express these transporters. In addition, as a vascular disrupting agent (VDA), MPC-6827 appears to disrupt tumor microvasculature specifically, which may result in acute ischemia and massive tumor cell death. Synonyms: MPC6827; MPC-6827; MPC 6827; MX128495; MX-128495; MX 128495; EP90745; EP-90745;EP 90745; Verubulin; trade name: Azixa. Grades: ≥98%. CAS No. 827031-83-4. Molecular formula: C21H25BrN3O9P. Mole weight: 279.34.
Verucerfont
Verucerfont is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50s of ~6.1, >1000 and >1000?nM for CRF1, CRF2, and CRF-BP, respectively. Verucerfont supresses the CRH-1 receptor to decrease ACTH release following chronic stress. Synonyms: GSK561679; GSK 561679; GSK-561679; GSK561679A; NBI-77860; NBI 77860; NBI77860; 3-(4-methoxy-2-methylphenyl)-2,5-dimethyl-N-[(1S)-1-(3-methyl-1,2,4-oxadiazol-5-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine. CAS No. 885220-61-1. Molecular formula: C22H26N6O2. Mole weight: 406.49.
Verucopeptin
It is an antibiotic produced by the strain of Actinomadura verrucosospora Q886-2. It has weak antimicrobial effect and can prolong the survival time of mice transplanted with melanoma. Verucopeptin strongly inhibits v-ATPase activity by directly targeting the v-ATPase ATP6V1G subunit but not ATP1V1B2 or ATP6V1D. Synonyms: 2-hydroxy-N-(17-hydroxy-8,14-dimethyl-2,6,9,12,15,18-hexaoxo-4-propan-2-yl-5-oxa-1,8,11,14,17,23-hexazabicyclo[17.4.0]tricosan-3-yl)-2-[2-hydroxy-5-methoxy-6-[(E)-4,6,8-trimethyldec-2-en-2-yl]oxan-2-yl]propanamide. Grades: 98%. CAS No. 138067-14-8. Molecular formula: C43H73N7O13. Mole weight: 896.08.
very-long-chain 3-oxoacyl-CoA reductase
The second component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. The enzyme is active with substrates with chain length of C16 to C34, depending on the species. cf. EC 2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase, and EC 1.3.1.93, very-long-chain enoyl-CoA reductase. Group: Enzymes. Synonyms: very-long-chain 3-ketoacyl-CoA reductase; very-long-chain β-ketoacyl-CoA reductase; KCR (gene name); IFA38 (gene name). Enzyme Commission Number: EC 1.1.1.330. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0244; very-long-chain 3-oxoacyl-CoA reductase; EC 1.1.1.330; very-long-chain 3-ketoacyl-CoA reductase; very-long-chain β-ketoacyl-CoA reductase; KCR (gene name); IFA38 (gene name). Cat No: EXWM-0244.
very-long-chain 3-oxoacyl-CoA synthase
This is the first component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. Multiple forms exist with differing preferences for the substrate, and thus the specific form expressed determines the local composition of very-long-chain fatty acids. For example, the FAE1 form from the plant Arabidopsis thaliana accepts only 16 and 18 carbon substrates, with oleoyl-CoA (18:1) being the preferred substrate, while CER6 from the same plant prefers substrates with chain length of C22 to C32. cf. EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase, and EC 1.3.1.93, very-long-chain enoyl-CoA reductase. Group: Enzymes. Synonyms: very-long-chain 3-ketoacyl-CoA synthase; very-long-chain β-ketoacyl-CoA . Enzyme Commission Number: EC 2.3.1.199. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2142; very-long-chain 3-oxoacyl-CoA synthase; EC 2.3.1.199; very-long-chain 3-ketoacyl-CoA synthase; very-long-chain β-ketoacyl-CoA synthase; condensing enzyme (ambiguous); CUT1 (gene name); CER6 (gene name); FAE1 (gene name); KCS (gene name); ELO (gene name). Cat No: EXWM-2142.
This is the third component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long chain acyl CoAs. cf. EC 2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, and EC 1.3.1.93, very-long-chain enoyl-CoA reductase. Group: Enzymes. Synonyms: PHS1 (gene name); PAS2 (gene name). Enzyme Commission Number: EC 4.2.1.134. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4975; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; EC 4.2.1.134; PHS1 (gene name); PAS2 (gene name). Cat No: EXWM-4975.
very-long-chain acyl-CoA dehydrogenase
Contains FAD as prosthetic group. One of several enzymes that catalyse the first step in fatty acids β-oxidation. The enzyme is most active toward long-chain acyl-CoAs such as C14, C16 and C18, but is also active with very-long-chain acyl-CoAs up to 24 carbons. It shows no activity for substrates of less than 12 carbons. Its specific activity towards palmitoyl-CoA is more than 10-fold that of the long-chain acyl-CoA dehydrogenase. cf. EC 1.3.8.1, short-chain acyl-CoA dehydrogenase, EC 1.3.8.7, medium-chain acyl-CoA dehydrogenase, and EC 1.3.8.8, long-chain acyl-CoA dehydrogenase. Group: Enzymes. Synonyms: ACADVL (gene name). Enzyme Commission Number: EC 1.3.8.9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1416; very-long-chain acyl-CoA dehydrogenase; EC 1.3.8.9; ACADVL (gene name). Cat No: EXWM-1416.
very-long-chain enoyl-CoA reductase
This is the fourth component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. cf. EC 2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC 1.1.1.330, very-long-chain 3-oxoacyl-CoA reductase, and EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase. Group: Enzymes. Synonyms: TSC13 (gene name); CER10 (gene name). Enzyme Commission Number: EC 1.3.1.93. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1363; very-long-chain enoyl-CoA reductase; EC 1.3.1.93; TSC13 (gene name); CER10 (gene name). Cat No: EXWM-1363.
Vesatolimod
Vesatolimod (GS-9620) is a potent, selective and orally active agonist of Toll-Like Receptor (TLR7) with an EC 50 of 291 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-9620. CAS No. 1228585-88-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15601.
Vesencumab
Vesencumab (MNRP-1685A) is IG1 antibody against neuropilin-1 (NRP-1). Vesencumab binds to NRP-1 and prevents the subsequent coupling of NRP-1 to VEGFR-2. Vesencumab has anti-angiogenic and anti-neoplastic activities. Vesencumab can be used in the research of metastatic solid tumors, including ovarian cancer[1][2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: MNRP-1685A. CAS No. 1205533-60-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99386.
vesicle-fusing ATPase
A large family of ATP-hydrolysing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. They include peroxin, which apparently is involved in Zellweger's syndrome. Group: Enzymes. Enzyme Commission Number: EC 3.6.4.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4708; vesicle-fusing ATPase; EC 3.6.4.6. Cat No: EXWM-4708.
Vesicular Stomatitis Virus Nucleoprotein (52-59)
Vesicular Stomatitis Virus Nucleoprotein (52-59) (VSV-8), corresponding to positions 52 to 59 of the vesicular stomatitis virus (VSV) nuclear protein, is expressed in the cytosol of VSV-infected cells. CTL response to VSV in H-2Kb mice is directed against this immunodominant peptide. VSV-8 forms a complex with the mouse MHC Class I molecule H-2Kb, similar to the human HLA Class I. Synonyms: VSV-8; H-Arg-Gly-Tyr-Val-Tyr-Gln-Gly-Leu-OH; L-Leucine, L-arginylglycyl-L-tyrosyl-L-valyl-L-tyrosyl-L-glutaminylglycyl-; N5-(Diaminomethylene)-L-ornithylglycyl-L-tyrosyl-L-valyl-L-tyrosyl-L-glutaminylglycyl-L-leucine. Grades: ≥95%. CAS No. 132326-74-0. Molecular formula: C44H66N12O12. Mole weight: 955.08.
Vesnarinone
Vesnarinone, a quinolinone derivative, is a cardiotonic agent. It has pharmacodynamic effects include inhibition of phosphodiesterase III (PDE3) activity, increases in calcium flux and decreases in potassium flux. Its IC50 value is 1 μM and 300 μM for inhibition of HERG channels and PDE. It is a novel cytokine inhibitor, for the treatment of lung fibrosis using a murine model of bleomycin (BLM)-induced pulmonary fibrosis. It is a new and novel inotropic drug that has unique and complex mechanisms of action. It inhibits phosphodiesterase, thereby leading to increased intracellular calcium, and also affects numerous myocardial ion channels, resulting in the prolongation of the open...eby leading to increased intracellular calcium, and also affects numerous myocardial ion channels, resulting in the prolongation of the opening time of sodium channels and the decrease in the delayed outward and inward rectifying potassium current. it improves ventricular performance most in patients with the worst degree of heart failure. Synonyms: RG-0210; RG 0210; RG0210; OPC-8212; OPC 8212; OPC8212; Piteranometozine; Vesnarinone; Arkin; Arkin-Z. OPC 8212;6-[4-(3,4-Dimethoxybenzoyl)-1-piperazinyl]-3,4-dihydro-2(1H)-quinolinone;3,4-Dihydro-6-(4-(3,4-dimethoxybenzoyl)-1-piperazinyl)-2(1h)-quinolinone. Grades: >98%. CAS No. 81840-15-5. Molecular formula: C22H25N3O4. Mole weight: 395.45.
Vesnarinone
Vesnarinone (OPC-8212) is an orally active phosphodiesterase 3 ( PDE3 ) inhibitor. Vesnarinone can increase in calcium flux and decrease in potassium flux. Vesnarinone shows dose-dependent positive inotropic activity. Vesnarinone can be used in heart failure research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC-8212. CAS No. 81840-15-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15297.
Vesnarinone
Vesnarinone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: VESNARINONE;0PC-8212;3,4-Dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-quinolinone;Arkin;Piteranometozine. Product Category: Heterocyclic Organic Compound. CAS No. 81840-15-5. Molecular formula: C22H25N3O4. Mole weight: 395.457. Product ID: ACM81840155. Alfa Chemistry ISO 9001:2015 Certified.
Vespid chemotactic peptide 5g
Vespid chemotactic peptide 5g is an antibacterial peptide isolated from Vespa magnifica. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: H-Phe-Leu-Ile-Ile-Arg-Arg-Pro-Ile-Val-Leu-Gly-Leu-Leu-OH. Grades: >95%. Molecular formula: C75H131N19O14. Mole weight: 1523.
VESP-VB1
VESP-VB1 is an antibacterial peptide isolated from Vespa bicolor. Synonyms: Phe-Met-Pro-Ile-Ile-Gly-Arg-Leu-Met-Ser-Gly-Ser-Leu. Molecular formula: C64H108N16O16S2. Mole weight: 1421.78.
Vestipitant
Cas No. 334476-64-1.
Vestitol
Vestitol. Group: Biochemicals. Grades: Highly Purified. CAS No. 35878-41-2. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C16H16O4. US Biological Life Sciences.
Worldwide
Vestitol
Vestitol is the compound isolated from leaves of Trifolium arvense [1]. Uses: Scientific research. Group: Natural products. Alternative Names: (±)-Vestitol. CAS No. 56701-24-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N8744.
vestitone reductase
This plant enzyme catalyses the penultimate step in the biosynthesis of the pterocarpin phytoalexins medicarpin and maackiain. This activity was previously classified as part of EC 1.1.1.246, pterocarpin synthase, which is now known to be catalysed by two enzymes, vestitone reductase and EC 4.2.1.139, medicarpin synthase. Group: Enzymes. Synonyms: pterocarpin synthase (incorrect); pterocarpan synthase (incorrect). Enzyme Commission Number: EC 1.1.1.348. CAS No. 118477-70-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0263; vestitone reductase; EC 1.1.1.348; 118477-70-6; pterocarpin synthase (incorrect); pterocarpan synthase (incorrect). Cat No: EXWM-0263.
The initial internal cyclization produces the monocyclic intermediate germacrene A. Group: Enzymes. Synonyms: vetispiradiene-forming farnesyl pyrophosphate cyclase; pemnaspirodiene synthase; HVS; vetispiradiene cyclase. Enzyme Commission Number: EC 4.2.3.21. CAS No. 192465-18-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5178; vetispiradiene synthase; EC 4.2.3.21; 192465-18-2; vetispiradiene-forming farnesyl pyrophosphate cyclase; pemnaspirodiene synthase; HVS; vetispiradiene cyclase. Cat No: EXWM-5178.
Vetiver is a parennial grass that shares a lot of its characteristics with other fragrant grasses like lemongrass, citronella and palmarosa. However unlike these plants, vetiver oil is extracted from the plant's roots rather than its leaves While Vetiver Oil is mainly used in fine fragrances, the Indonesian Vetiver is widely used for making derivatives such as Vetiverol and Vetiveryl Acetate. Uses: Aromatherapy. Group: Plant Extracts. INCI Names: Vetiveria Zizanioides (Vetiver) Root Oil. Grades: INDUSTRIAL GRADE. CAS No. 84238-29-9. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: VT-006. Olfactive Profile: Woody, earthy, rooty, smokey, nutty, powdery, sweet. EC No: 282-490-8. Origin: Indonesia.
New Jersey
Vetiver Oil Haiti
Vetiver Oil Haiti. CAS No. 8016-96-4. Kosher: Y. VIGON Item # 504190. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers, Cosmetics.
America & Internationally
Vetiver Oil Java Crude
Vetiver is a parennial grass that shares a lot of its characteristics with other fragrant grasses like lemongrass, citronella and palmarosa. However unlike these plants, vetiver oil is extracted from the plant's roots rather than its leaves While Vetiver Oil is mainly used in fine fragrances, the Indonesian Vetiver is widely used for making derivatives such as Vetiverol and Vetiveryl Acetate. Uses: Cosmetic and Care, Essential Oils. Group: Plant Extracts. INCI Names: Vetiveria Zizanioides (Vetiver) Root Oil. Grades: INDUSTRIAL GRADE. CAS No. 84238-29-9 ; 8016-96-4. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: VT-001. Olfactive Profile: Woody, smoky, earthy, herbaceous and spicy, sweet, caramel. EC No: 282-490-8. Origin: Indonesia.
New Jersey
Vetiver Oil Java M.D.
Vetiver is a parennial grass that shares a lot of its characteristics with other fragrant grasses like lemongrass, citronella and palmarosa. However unlike these plants, vetiver oil is extracted from the plant's roots rather than its leaves. Uses: Perfumery, Cosmetics. Group: Plant Extracts. INCI Names: Vetiveria Zizanioides (Vetiver) Root Oil. Grades: INDUSTRIAL GRADE. CAS No. 84238-29-9 ; 8016-96-4. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: VT-003. Olfactive Profile: Woody, smoky, earthy, herbaceous and spicy, sweet, caramel. EC No: 282-490-8. Origin: Indonesia.
New Jersey
Vetiver Oil Java Rectified
Vetiver is a parennial grass that shares a lot of its characteristics with other fragrant grasses like lemongrass, citronella and palmarosa. However unlike these plants, vetiver oil is extracted from the plant's roots rather than its leaves While Vetiver Oil is mainly used in fine fragrances, the Indonesian Vetiver is widely used for making derivatives such as Vetiverol and Vetiveryl Acetate. Uses: Cosmetic and Care, Essential Oils. Group: Plant Extracts. INCI Names: Vetiveria Zizanioides (Vetiver) Root Oil. Grades: INDUSTRIAL GRADE. CAS No. 84238-29-9 ; 8016-96-4. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: VT-002. Olfactive Profile: Woody, smoky, earthy, herbaceous and spicy, sweet, caramel. EC No: 282-490-8. Origin: Indonesia.
New Jersey
Vetivert acetate
Vetivert acetate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Vetiver acetate, Vetivert acetate, Vetiveryl acetate, Vetiverol, acetate, Vetiver acetate, Java, W524301_ALDRICH, EINECS 263-597-9, EINECS 204-225-7, AI3-24214, LS-3152, Vetiveryl acetate (Vetiveria zizanioides (L.) Nash), 1,2,3,3a,4,5,6,8a-Octahydro-2-isopropylidene-4,8-dimethylazulen-6-yl acetate, 6-AZULENOL, 1,2,3,3a,4,5,6,8a-OCTAHYDRO-2-ISOPROPYLIDENE-4,8-DIMETHYL-, ACETATE, 6-Azulenol, 1,2,3,3a,4,5,6,8a-octahydro-4,8-dimethyl-2-(1-methylethylidene)-, acetate, 117-98-6, 62563-80-8. Product Category: Heterocyclic Organic Compound. CAS No. 62563-80-8. Molecular formula: C17H26O2. Mole weight: 262.3871. Purity: N/A. IUPACName: (4,8-dimethyl-2-propan-2-ylidene-3,3a,4,5,6,8a-hexahydro-1H-azulen-6-yl) acetate. Canonical SMILES: CC1CC(C=C(C2C1CC(=C(C)C)C2)C)OC(=O)C. Density: 0.976 g/mL at 25ºC(lit.). ECNumber: 204-225-7. Product ID: ACM62563808. Alfa Chemistry ISO 9001:2015 Certified.
Vetiveryl Acetate
Vetiver is a parennial grass that shares a lot of its characteristics with other fragrant grasses like lemongrass, citronella and palmarosa. However unlike these plants, vetiver oil is extracted from the plant's roots rather than its leaves While Vetiver Oil is mainly used in fine fragrances, the Indonesian Vetiver is widely used for making derivatives such as Vetiverol and Vetiveryl Acetate. Uses: Cosmetic and Care, Fragrance Products. Group: Plant Extracts. INCI Names: Vetiveryl Acetate. Grades: FOOD GRADE. CAS No. 84082-84-8. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: VT-005. Olfactive Profile: Woody, smoky, earthy, herbaceous and spicy, sweet, caramel. EC No: 282-031-1. FEMA No: 4218. Origin: Indonesia.
VGX-1027 is an orally active isoxazole compound that exhibits various immunomodulatory properties. VGX-1027 targets macrophages, reducing the production of the proinflammatory mediators TNF-α, IL-1β, IL-10. VGX-1027 has antidiabetogenic effects by limiting cytokine-mediated immunoinflammatory events [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GIT 27. CAS No. 6501-72-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15507.
VH032
VH032 is a VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. VH032 is a VHL/HIF-1? interaction inhibitor with a Kd
VH 032-linker 6
VH 032-linker 6 is a von-Hippel-Lindau protein ligand (VHL) conjugated to a PEGylated crosslinker with terminal alkyne for PROTAC technology. It has been used as a degrader building block in PROTAC for targeted protein degradation. Synonyms: VH032-PEG3-acetylene; (2S,4R)-1-((S)-2-(tert-Butyl)-4-oxo-6,9,12-trioxa-3-azapentadec-14-yn-1-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide. Grades: ≥98%. CAS No. 2098799-80-3. Molecular formula: C31H42N4O7S. Mole weight: 614.75.
VH285-PEG4-C4-Cl
VH285-PEG4-C4-Cl (HaloPROTAC 3) is a conjugate of ligands for E3 and 16-atom-length linker. The connector of linker is Halogen group. VH285-PEG4-C4-Cl incorporates the VH285 based VHL ligand and an alkyl/ether-based linker. VH285-PEG4-C4-Cl is a highly potent and efficacious degrader of GFP-HaloTag7 with a DC50 of 19 nM. VH285-PEG4-C4-Cl is able to induce 90 % degradation of GFP-Halotag at 625 nM. VH285-PEG4-C4-Cl binds to VHL with an IC50 of 0.54 ?M[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: HaloPROTAC 3. CAS No. 1799506-07-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111997.
VH-298 is a highly potent inhibitor of the VHL:HIF-? interaction with a Kd value of 80 to 90 nM. VH-298 leads to HIF-? accumulation inside HeLa cells. VH-298 is an E3 ligase Ligand, and can be used for synthesis of PROTACs[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2097381-85-4. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100947.
VH-298
VH-298 is a high-affinity inhibitor of E3 ubiquitin ligase VHL (Kd value of 80-90 nM) that could block VHL and HIF-α interactions. VH-298 can be used in PROTAC technology. Uses: Enzyme inhibitors. Synonyms: (2S,4R)-1-((S)-2-(1-cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide; EX-A1505; VH 298; VH298; VH-298. Grades: ≥98% by HPLC. CAS No. 2097381-85-4. Molecular formula: C27H33N5O4S. Mole weight: 523.65.
Vhl-1
Vhl-1 is a cyclic peptide isolated from Viola hederacea (Australian violet), which has antibacterial and antiviral activities. Synonyms: Leaf cyclotide 1; Ser-Ile-Ser-Cys-Gly-Glu-Ser-Cys-Ala-Met-Ile-Ser-Phe-Cys-Phe-Thr-Glu-Val-Ile-Gly-Cys-Ser-Cys-Lys-Asn-Lys-Val-Cys-Tyr-Leu-Asn.
Vhl-2
Vhl-2 is a cyclic peptide isolated from Viola hederacea (Australian violet), which has antibacterial and antiviral activities. Synonyms: Leaf cyclotide 2; Gly-Leu-Pro-Val-Cys-Gly-Glu-Thr-Cys-Phe-Thr-Gly-Thr-Cys-Tyr-Thr-Asn-Gly-Cys-Thr-Cys-Asp-Pro-Trp-Pro-Val-Cys-Thr-Arg-Asn. Molecular formula: C33H41N5O5S. Mole weight: 619.8.
VHL human
recombinant, expressed in insect cells, ?70% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
Vhr1
Vhr1 is a cyclic peptide isolated from Viola hederacea (Australian violet), which has antibacterial and antiviral activities. Synonyms: Gly-Ile-Pro-Cys-Ala-Glu-Ser-Cys-Val-Trp-Ile-Pro-Cys-Thr-Val-Thr-Ala-Leu-Leu-Gly-Cys-Ser-Cys-Ser-Asn-Lys-Val-Cys-Tyr-Asn.
Vialinin A
Vialinin A (Terrestrin A) is a p-terphenyl compound with antioxidant properties [1]. Vialinin A is a potent inhibitor of TNF-α, USP4, USP5, and sentrin/SUMO-specific protease 1 (SENP1). Vialinin A (Terrestrin A) can be used for autoimmune diseases and cancer research [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Terrestrin A. CAS No. 858134-23-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-103435.
Vialinin A
Vialinin A. Group: Biochemicals. Grades: Purified. CAS No. 858134-23-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Vialinin A
Vialinin A is an inhibitor of ubiquitin-specific peptidase 4 (USP4), USP5/isopeptidase T (IsoT) and UCH-L1 deubiquitinating enzyme (DUB) activity (IC50 = 1.5, 5.9 and 22.3 μM, respectively), displaying no significant inhibitory effects on UCH-L3, USP2, and USP8 activity. Vialinin A has been shown to reduce the release of TNF-α (IC50 = 0.09 nM) from RBL-2H3 mast cells. Synonyms: 1,1'-(4,4'',5',6'-Tetrahydroxy[1,1':4',1''-terphenyl]-2',3'-diyl) benzeneacetic acid ester; Ganbajunin C. Grades: ≥98% by HPLC. CAS No. 858134-23-3. Molecular formula: C34H26O8. Mole weight: 562.57.
Viba 15
Viba 15 is a cyclic peptide isolated from Viola hederacea (Australian violet), which has antibacterial activities. Synonyms: Gly-Leu-Pro-Val-Cys-Gly-Glu-Thr-Cys-Val-Gly-Gly-Thr-Cys-Asn-Thr-Pro-Gly-Cys-Ala-Cys-Ser-Trp-Pro-Val-Cys-Thr-Arg-Asn. Mole weight: 2860.
Viba17
Viba17 is a cyclic peptide isolated from Viola hederacea (Australian violet), which has antibacterial activities. Synonyms: Gly-Leu-Pro-Val-Cys-Gly-Glu-Thr-Cys-Val-Gly-Gly-Thr-Cys-Asn-Thr-Pro-Gly-Cys-Gly-Cys-Ser-Trp-Pro-Val-Cys-Thr-Arg-Asn. Mole weight: 2846.02.
Vibecotamab
Vibecotamab (XmAb14045) is a potent bispecific antibody against CD123 and CD3 that stimulates T cell-mediated targeted killing of CD123-expressing cells. Vibecotamab has antitumor activity and can be used in acute myeloid leukaemia studies [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: XmAb14045. CAS No. 2138442-13-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99521.
Vibegron
Vibegron (MK-4618) is a potent, highly selective and orally active β 3 -adrenoceptor agonist ( EC 50 =1.1 nM). Vibegron can be used for severe urgency urinary incontinence related to overactive bladder [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MK-4618. CAS No. 1190389-15-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19933.
VIBEGRON
This active molecular is a selective Beta 3 Adrenergic Receptor Agonist and was developed by Kyorin Pharmaceutical for the treatment of OAB (Overactive Bladder). Now, Vibegron is in Phase 3 human clinical trials for the treatment of OAB. In Jan 2015, Vibegron was discontinued Phase-I for hypertension (Combination therapy) in USA. In Mar 2016, Vibegron licensed to Kissei Pharmaceutical in Japan. Uses: Overactive bladder. Synonyms: (6S)-N-[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]-4-oxo-7,8-dihydro-6H-pyrrolo[1,2-a]pyrimidine-6-carboxamide,MK-4618; MK 4618; MK4618; Vibegron. Grades: 98%. CAS No. 1190389-15-1. Molecular formula: C26H28N4O3. Mole weight: 444.54.
Vibegron Impurity 10
Vibegron Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1865729-64-1. Molecular formula: C31H36N4O5. Mole weight: 544.65. Catalog: APB1865729641.
Vibegron Impurity 4
Vibegron Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1009092-91-4. Molecular formula: C17H25NO4. Mole weight: 307.39. Catalog: APB1009092914.
Vibi A
Vibi A is a plant antimicrobial peptide isolated from Viola hederacea (Australian violet). It has activity against bacteria and cancer cells. Synonyms: Gly-Leu-Pro-Val-Cys-Gly-Glu-Thr-Cys-Phe-Gly-Gly-Thr-Cys-Asn-Thr-Pro-Gly-Cys-Ser-Cys-Ser-Tyr-Pro-Ile-Cys-Thr-Arg-Asn.
Vibi B
Vibi B is a plant antimicrobial peptide isolated from Viola hederacea (Australian violet). It has activity against bacteria and cancer cells. Synonyms: Gly-Leu-Pro-Val-Cys-Gly-Glu-Thr-Cys-Phe-Gly-Gly-Thr-Cys-Asn-Thr-Pro-Gly-Cys-Thr-Cys-Ser-Tyr-Pro-Ile-Cys-Thr-Arg-Asn.
Vibi C
Vibi C is a plant antimicrobial peptide isolated from Viola hederacea (Australian violet). It has activity against bacteria and cancer cells. Synonyms: Gly-Leu-Pro-Val-Cys-Gly-Glu-Thr-Cys-Ala-Phe-Gly-Ser-Cys-Tyr-Thr-Pro-Gly-Cys-Ser-Cys-Ser-Trp-Pro-Val-Cys-Thr-Arg-Asn.
Vibi D
Vibi D is a plant antimicrobial peptide isolated from Viola hederacea (Australian violet). It has activity against bacteria and cancer cells. Synonyms: Gly-Leu-Pro-Val-Cys-Gly-Glu-Thr-Cys-Phe-Gly-Gly-Arg-Cys-Asn-Thr-Pro-Gly-Cys-Thr-Cys-Ser-Tyr-Pro-Ile-Cys-Thr-Arg-Asn.
Vibi F
Vibi F is a plant antimicrobial peptide isolated from Viola hederacea (Australian violet). It has activity against bacteria and cancer cells. Synonyms: Gly-Thr-Ile-Pro-Cys-Gly-Glu-Ser-Cys-Val-Phe-Ile-Pro-Cys-Leu-Thr-Ser-Ala-Leu-Gly-Cys-Ser-Cys-Lys-Ser-Lys-Val-Cys-Tyr-Lys-Asn.
Vibi G
Vibi G is a plant antimicrobial peptide isolated from Viola hederacea (Australian violet). It has activity against bacteria and cancer cells. Synonyms: Gly-Thr-Phe-Pro-Cys-Gly-Glu-Ser-Cys-Val-Phe-Ile-Pro-Cys-Leu-Thr-Ser-Ala-Ile-Gly-Cys-Ser-Cys-Lys-Ser-Lys-Val-Cys-Tyr-Lys-Asn.
Vibi I
Vibi I is a plant antimicrobial peptide isolated from Viola hederacea (Australian violet). It has activity against bacteria and cancer cells. Synonyms: Gly-Ile-Pro-Cys-Gly-Glu-Ser-Cys-Val-Trp-Ile-Pro-Cys-Leu-Thr-Ser-Thr-Val-Gly-Cys-Ser-Cys-Lys-Ser-Lys-Val-Cys-Tyr-Arg-Asn.