A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Vibralactone K is isolated from Boreostereum vibrans and has no cytotoxicity against five human cancer cell lines. Synonyms: 1H-Cyclopenta[c]furan-1-one, hexahydro-6-hydroxy-5-(3-methyl-2-buten-1-yl)-, (3aS,5S,6R,6aR)-. Grades: ≥98%. CAS No. 1623786-66-2. Molecular formula: C12H18O3. Mole weight: 210.27.
Vibralactone L
Vibralactone L is isolated from Boreostereum vibrans and has no cytotoxicity against five human cancer cell lines. Synonyms: 3-Furanpropanoic acid, 2,5-dihydro-α-(3-methyl-2-buten-1-yl)-5-oxo-, ethyl ester, (+)-. Grades: ≥98%. CAS No. 1623786-67-3. Molecular formula: C14H20O4. Mole weight: 252.31.
Vibration Pad
Vibration Pad. Group: Polymers.
vibriolysin
Thermostable enzyme from Vibrio proteolyticus (formerly Aeromonas proteolytica). Specificity related to, but distinct from, those of thermolysin and bacillolysin. A zinc metallopeptidase in family M4 (thermolysin family). Formerly included in EC 3.4.24.4. Group: Enzymes. Synonyms: Aeromonas proteolytica neutral proteinase; aeromonolysin. Enzyme Commission Number: EC 3.4.24.25. CAS No. 69598-88-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4306; vibriolysin; EC 3.4.24.25; 69598-88-5; Aeromonas proteolytica neutral proteinase; aeromonolysin. Cat No: EXWM-4306.
Vibunazole
Vibunazole is usually used as an antifungal agent. Uses: Antifungal agent. Synonyms: Bay N 7133; BayN 7133; Bay-N 7133; Vibunazole; α-[(4-Chlorophenoxy)?methyl]?-α-(1,?1-dimethylethyl)?-1H-1,?2,?4-triazole-1-ethanol. Grades: 98%. CAS No. 80456-55-9. Molecular formula: C15H20ClN3O2. Mole weight: 309.79.
Viburgenin
Viburgenin, an extract isolated from Rudgea viburnioides, is a triterpenes that shows an antifungal and anticancer activity. Synonyms: (+)-Viburgenin. CAS No. 211506-71-7. Molecular formula: C30H50O5. Mole weight: 490.73.
Vicagrel
Vicagrel is a potent, safe and orally active antiplatelet agent, which works by irreversibly inhibiting P2Y12 receptor. Vicagrel can be used for the research of blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1314081-53-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118284.
Vicagrel
Vicagrel is a prodrug of clopidogrel thiolactone, an oral P2Y12 antiplatelet agent used to prevent blood clots, developed to overcome clopidogrel resistance. Currently, Vicagrel is undergoing a phase I active study by Jiangsu Vcare Pharmatech. Synonyms: CHEMBL2042273; SCHEMBL12438770; ZINC84654546; AJ-126334; methyl (2S)-2-(2-acetyloxy-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)-2-(2-chlorophenyl)acetate. CAS No. 1314081-53-2. Molecular formula: C18H18ClNO4S. Mole weight: 379.87.
Vicagrel Carboxylic Acid
An impurity of Vicagrel. Vicagrel is a prodrug of clopidogrel thiolactone, an oral P2Y12 antiplatelet agent used to prevent blood clots, developed to overcome clopidogrel resistance. Currently, Vicagrel is undergoing a phase I active study by Jiangsu Vcare Pharmatech. Molecular formula: C17H16ClNO4S. Mole weight: 365.84.
Vicanicin
Vicanicin is a depsidone isolated from the lichen Teloschistesflavicans (Sw.) Norm. Vicanicin can induce apoptosis of DU-145 and LNCaP cells. Synonyms: 2,7-Dichloro-3-hydroxy-8-methoxy-1,4,6,9-tetramethyl-11H-dibenzo[b,e][1,4]dioxepin-11-one. CAS No. 33211-22-2. Molecular formula: C18H16Cl2O5. Mole weight: 383.22.
Vicenin 2
Vicenin 2, a flavonoid, is an orally active angiotensin-converting enzyme (ACE) inhibitor ( IC 50 of 43.83 μM) [1]. Vicenin 2 has radioprotective, anti-nociceptive effects, anti-glycation anti-inflammatory, antioxidant, anticancer, antiangiogenic properties [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 23666-13-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2165.
Vicenin-2
Vicenin-2. Group: Biochemicals. CAS No. 23666-13-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Vicenin-II (6,8-Di-C-glucosylapigenin)
Vicenin-II (6,8-Di-C-glucosylapigenin). Group: Biochemicals. Alternative Names: 6, 8-Di-C-glucopyranosyl apigenin; 6,8-Di-C-glucosylapigenin. Grades: Plant Grade. CAS No. 23666-13-9. Pack Sizes: 10mg. Molecular Formula: C27H30O15, Molecular Weight: 594.518. US Biological Life Sciences.
Worldwide
Vicenin III (6-C-Glucosyl-8-C-xylosylapigenin)
Vicenin III (6-C-Glucosyl-8-C-xylosylapigenin). Group: Biochemicals. Alternative Names: Vicenin 3; 6-C-Glucosyl-8-C-xylosylapigenin; 6-beta-D-Glucopyranosyl-8-beta-D-xylopyranosylapigenin. Grades: Plant Grade. CAS No. 59914-91-9. Pack Sizes: 10mg. Molecular Formula: C26H28O14, Molecular Weight: 564.491999999999. US Biological Life Sciences.
Worldwide
Vicenistatin
It is a macrocyclic lipid antibiotic produced by the strain of Str. sp. HC34. In vitro it is cytotoxic to human leukemia HL-60 cells and human colon cancer Co-LO205 cells with IC50 (μg/mL) of 0.12 and 0.19, respectively. Synonyms: Azacycloeicosa-3,5,10,13,15-pentaen-2-one, 7,11,13,19-tetramethyl-8-[[2,4,6-trideoxy-4-(methylamino)-β-D-ribo-hexopyranosyl]oxy]-, (3E,5E,7S,8S,10E,13E,15E,19S)-; Antibiotic HC34; NSC 641691; Vicenistatine. CAS No. 150999-05-6. Molecular formula: C30H48N2O4. Mole weight: 500.71.
Vicenistatin M
It is produced by the strain of Streptomyces sp. HC-34. It is a homologue of Mycarose replacing amino sugars in the Vicenstatin molecule, and it loses the cytotoxicity of Vicenstatin. Synonyms: (6S,7S,18S)-20-aza-6,10,12,18-tetramethyl-7-O-(2',6'-dideoxy-3'-C-methyl-β-D-ribo-hexopyranosyl)-cycloicosa-2,4,9,12,14-pentaen-1-one; (3E,5E,10E,13E,15E)-(7S,8S,19S)-8-((2R,4S,5R,6R)-4,5-Dihydroxy-4,6-dimethyl-tetrahydro-pyran-2-yloxy)-7,11,13,19-tetramethyl-azacycloicosa-3,5,10,13,15-pentaen-2-one; Vicenistatine M. CAS No. 312532-50-6. Molecular formula: C30H47NO5. Mole weight: 501.70.
vicianin β-glucosidase
Also hydrolyses, more slowly, (R)-amygdalin and (R)-prunasin, but not gentiobiose, linamarin or cellobiose. Group: Enzymes. Synonyms: vicianin hydrolase. Enzyme Commission Number: EC 3.2.1.119. CAS No. 91608-93-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3802; vicianin β-glucosidase; EC 3.2.1.119; 91608-93-4; vicianin hydrolase. Cat No: EXWM-3802.
Vicianose
Vicianose is an extensively utilized carbohydrate compound within the biomedical industry, used in studying diabetes and various metabolic disorders. Synonyms: 6-O-α-L-Arabinopyranosyl-D-glucose. CAS No. 14116-69-9. Molecular formula: C11H20O10. Mole weight: 312.27.
Vicia sativa, ext.
Vicia sativa, ext. Uses: Designed for use in research and industrial production. Additional or Alternative Names: WHEAT GERM AGGLUTININ;WHEAT GERM AGGLUTININ AGAROSE BOUND;WGA;WGA-AGAROSE;WGA AGAROSE BOUND;WHEAT GERM AGGLUTININ, IMMOBILIZED ON AGAROSE CL-4B;WHEAT GERM LECTIN-AGAROSE;TRITICUM VULGARIS-AGAROSE. Product Category: Heterocyclic Organic Compound. CAS No. 96508-08-6. Purity: 0.96. Product ID: ACM96508086. Alfa Chemistry ISO 9001:2015 Certified.
Vicine
Vicine is an alkaloid glycoside found mainly in fava beans. It is related to the loss of the enzyme glucose-6-phosphate dehydrogenase. Uses: Anti-arrhythmic. Synonyms: 2,6-diamino-5-(beta-D-glucopyranosyloxy)-(1H)-pyrimidin-4-one; 2,6-Diamino-5-(β-D-glucopyranosyloxy)-4(1H)-pyrimidinone; 2,6-Diamino-5-(β-D-glucopyranosyloxy)pyrimidin-4-ol; Divicine β-D-glucopyranoside; Vicine[phytotoxin]; Vicioside; 2,6-Diamino-5-(beta-D-glucopyranosyloxy)-4(1H)-pyrimidinone. Grades: >98%. CAS No. 152-93-2. Molecular formula: C10H16N4O7. Mole weight: 304.26.
Vicine
Vicine, an alkaloid glycoside found mainly in fava beans, is toxic in individuals who have a hereditary loss of the enzyme glucose-6-phosphate dehydrogenase and may cause haemolytic anaemia.Vicine is an inactive compound that is hydrolysed by the intestinal microflora to a highly reactive free radical generating compound, the aglycone divicine when Vicine enters the body through food [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 152-93-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N2093.
Vicin-like antimicrobial peptide 2a
Vicin-like antimicrobial peptide 2a is an antibacterial peptide isolated from Macadamia integrifolia. It has activity against bacteria and fungi. Synonyms: Gln-Cys-Met-Gln-Leu-Glu-Thr-Ser-Gly-Gln-Met-Arg-Arg-Cys-Val-Ser-Gln-Cys-Asp-Lys-Arg-Phe-Glu-Glu-Asp-Ile-Asp-Trp-Ser-Lys-Tyr-Asp-Asn-Gln-Glu.
Vicin-like antimicrobial peptide 2b
Vicin-like antimicrobial peptide 2b is an antibacterial peptide isolated from Macadamia integrifolia. It has activity against bacteria and fungi. Synonyms: Asp-Pro-Gln-Thr-Glu-Cys-Gln-Gln-Cys-Gln-Arg-Arg-Cys-Arg-Gln-Gln-Glu-Ser-Asp-Pro-Arg-Gln-Gln-Gln-Tyr-Cys-Gln-Arg-Arg-Cys-Lys-Glu-Ile-Cys-Glu-Glu-Glu-Glu-Glu-Tyr-Asn.
Vicin-like antimicrobial peptide 2c-1
Vicin-like antimicrobial peptide 2c-1 is an antibacterial peptide isolated from Macadamia integrifolia. It has activity against bacteria and fungi. Synonyms: Arg-Gln-Arg-Asp-Pro-Gln-Gln-Gln-Tyr-Glu-Gln-Cys-Gln-Glu-Arg-Cys-Gln-Arg-His-Glu-Thr-Glu-Pro-Arg-His-Met-Gln-Thr-Cys-Gln-Gln-Arg-Cys-Glu-Arg-Arg-Tyr-Glu-Lys-Glu-Lys-Arg-Lys-Gln-Gln.
Vicin-like antimicrobial peptide 2d
Vicin-like antimicrobial peptide 2d is an antibacterial peptide isolated from Macadamia integrifolia. It has activity against bacteria and fungi. Synonyms: Lys-Arg-Asp-Pro-Gln-Gln-Arg-Glu-Tyr-Glu-Asp-Cys-Arg-Arg-His-Cys-Glu-Gln-Gln-Glu-Pro-Arg-Leu-Gln-Tyr-Gln-Cys-Gln-Arg-Arg-Cys-Gln-Glu-Gln-Gln. Molecular formula: C183H293N69O62S4. Mole weight: 4580.
Vico A
Vico A is an antibacterial cyclic peptide isolated from Viola cotyledon, which may be involved in plant defense mechanisms. Synonyms: Cyclotide vico-A; Gly-Ser-Ile-Pro-Cys-Ala-Glu-Ser-Cys-Val-Tyr-Ile-Pro-Cys-Phe-Thr-Gly-Ile-Ala-Gly-Cys-Ser-Cys-Lys-Asn-Lys-Val-Cys-Tyr-Tyr-Asn.
Vico B
Vico B is an antibacterial cyclic peptide isolated from Viola cotyledon, which may be involved in plant defense mechanisms. Synonyms: Cyclotide vico-B; Gly-Ser-Ile-Pro-Cys-Ala-Glu-Ser-Cys-Val-Tyr-Ile-Pro-Cys-Ile-Thr-Gly-Ile-Ala-Gly-Cys-Ser-Cys-Lys-Asn-Lys-Val-Cys-Tyr-Tyr-Asn.
Vicriviroc
Vicriviroc is an antagonist of CCR5 receptor against human immunodeficiency virus. Vicriviroc inhibits the entry of HIV into CD4 cells via binding to CCR5. Synonyms: SCH-D; Sch-D compound; Sch 417690; UNII-TL515DW4QS; SCH-417690; (4,6-dimethylpyrimidin-5-yl)-[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl]methanone. CAS No. 306296-47-9. Molecular formula: C28H38F3N5O2. Mole weight: 533.64.
Vicriviroc Malate
Vicriviroc is a potent, orally active, selective inhibitor of CCR5 entry into HIV-1. It can effectively inhibit the initial stage of the virus life cycle. Synonyms: (4,6-dimethylpyrimidin-5-yl)-[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl]methanone; 2-hydroxybutanedioicacid; VicrivirocMalate; 541503-81-5; S2004_Selleck; MolPort-016-633-267. Grades: 98%. CAS No. 541503-81-5. Molecular formula: C28H38F3N5O2.C4H6O5. Mole weight: 667.72.
Vicriviroc maleate
Vicriviroc maleate (SCH-417690 maleate; SCH-D maleate) is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5 , with a K i of 2.5 nM, and also inhibits HIV-1 in PBMC cells, with IC 90 s of 3.3 nM (JrFL), 2.8 nM (ADA-M), 1.8 nM (301657), 4.9 nM (JV1083) and 10 nM (RU 570). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH-417690 maleate; SCH-D maleate. CAS No. 599179-03-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17377.
Vicriviroc maleate
Vicriviroc maleate is a CCR5 antagonist. Synonyms: 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-piperidine (2Z)-2-butenedioate (1:1). Grades: ≥98% (HPLC). CAS No. 599179-03-0. Molecular formula: C32H42F3N5O6. Mole weight: 649.7.
Victoria blue 4r
Victoria blue 4r. Uses: Designed for use in research and industrial production. Additional or Alternative Names: VICTORIA BLUE 4R;3,5-bis(1,1-dimethylethyl)-4-Benzenepropanoicacid;5-cyclohexadien-1-ylidene]-n-methyl-enyl]methylene]-chloride;methanaminium,n-[4-[[4-(dimethylamino)phenyl][4-(methylphenylamino)-1-naphthal;CI 42563;[4-[[4-(dimethylamino)phenyl][4-toluid. Appearance: Gold to dark brown crystalline powder. CAS No. 2185-87-7. Molecular formula: C34H34ClN3. Mole weight: 520.12. Purity: CI 42563. IUPACName: victoria blue 4R. Product ID: ACM2185877. Alfa Chemistry ISO 9001:2015 Certified. Categories: Victoria blue R.
Victoria Blue B
Victoria Blue B. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g. US Biological Life Sciences.
Worldwide
VICTORIA BLUE B
VICTORIA BLUE B. CAS No: 2580-56-5
Sarchem Laboratories New Jersey NJ
VICTORIA BLUE BO
VICTORIA BLUE BO. CAS No: 2390-60-5
Sarchem Laboratories New Jersey NJ
Victoria Blue R
Victoria Blue R. Group: Biochemicals. Grades: Reagent Grade. CAS No. 2185-86-6. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
VICTORIA BLUE R
VICTORIA BLUE R. CAS No: 2185-86-6
Sarchem Laboratories New Jersey NJ
Victoxinine
Victoxinine is a toxic metabolite of Helminthosporium victoriae. Synonyms: (4aalpha,8aalpha)-Decahydro-8-methyl-9-methylene-5beta-isopropyl-4beta,8beta-methanoisoquinoline-2-Ethanol; Victoxinin; 4,8-Methanoisoquinoline-2(1H)-Ethanol, octahydro-8-methyl-9-methylene-5-(1-methylethyl)-, (4R,4aR,5R,8R,8aS)-rel-(+)-. Grades: ≥98%. CAS No. 39965-06-5. Molecular formula: C17H29NO. Mole weight: 263.42.
Vidarabine
Vidarabine (Ara-A) an antiviral agent which is active against herpes simplex and varicella zoster viruses [1] [2]. Vidarabine has IC 50 s of 9.3 μg/ml for HSV-1 and 11.3 μg/ml for HSV-2 [2]. Vidarabine also has anti- orthopoxvirus activity [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Ara-A; Adenine Arabinoside; 9-β-D-Arabinofuranosyladenine. CAS No. 5536-17-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-B0277.
Vidarabine (Ara-A) an antiviral agent which is active against herpes simplex and varicella zoster viruses. Vidarabine has IC50s of 9.3 μg/ml for HSV-1 and 11.3 μg/ml for HSV-2. Vidarabine also has anti-orthopoxvirus activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ARABINOSYL-ADENINE;6-AMINO-9-BETA-D-ARABINOFURANOSYLPURINE;ADENINE-BETA-D-ARABINOFURANOSIDE;ADENINE-9-BETA-D-ARABINOFURANOSIDE;9-BETA-D-ARABINOSYLADENINE;9-BETA-D-ARABINOFURANOSYLADENINE;2-ARAADENOSINE;SPONGOADENOSINE. Product Category: Inhibitors. CAS No. 5536-17-4. Molecular formula: C10H13N5O4. Mole weight: 267.24. Purity: ≥98.0%. Product ID: ACM5536174. Alfa Chemistry ISO 9001:2015 Certified.
Vidarabine monohydrate
Vidarabine is a nucleoside antibiotic effective against herpes simplex virus types 1 (HSV-1), 2 (HSV-2) and varicella zoster viruses (VZV). Synonyms: Spongoadenosine monohydrate; Vira-A monohydrate; (2R,3S,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol hydrate. Grades: 99.96%. CAS No. 24356-66-9. Molecular formula: C10H13N5O4·H2O. Mole weight: 285.26.
Vidarabine monohydrate
Vidarabine monohydrate is an adenine arabinoside. Vidarabine monohydrate an antiviral agent which is active against herpes simplex viruses ( HSV ) and varicella zoster viruses [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 24356-66-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-N6666.
Vidarabine Monohydrate
Vidarabine Monohydrate. Group: Biochemicals. Alternative Names: 9- β-D-Arabinofuranosyl-9H-purin-6-amine Hydrate (1:1); 9- β -D-Arabinofuranosyl adenine Monohydrate; Adenine Arabinofuranoside Hydrate. Grades: Highly Purified. CAS No. 24356-66-9. Pack Sizes: 250mg. Molecular Formula: C10H15N5O5, Molecular Weight: 285.26. US Biological Life Sciences.
Worldwide
Vidarabine phosphate
Vidarabine phosphate (Ara-AMP), an antiviral agent, inhibits chronic HBV infection [1] [2]. Vidarabine phosphate also against herpes simplex and varicella zoster viruses [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ara-AMP; ara-A 5'-monophosphate. CAS No. 29984-33-6. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0277A.
Vidofludimus
Vidofludimus is an orally active and potent dihydroorotate dehydrogenase (DHODH) inhibitor with IC50 of 134 nM for human DHODH. Phase 2. Synonyms: SC12267, SC 12267; SC-12267; 4SC-101; 4SC 101; 4SC101. Grades: 98%. CAS No. 717824-30-1. Molecular formula: C20H18FNO4. Mole weight: 355.36.
Vidofludimus
Vidofludimus is an orally active inhibitor for dihydroorotate dehydrogenase (DHODH) and also is a novel modulator for farnesoid X receptor (FXR). Vidofludimus, as an immunomodulatory agent, can be used for the research of autoimmune disorders such as inflammatory bowel disease (IBD). Vidofludimus also can be used for the research of fatty liver by targeting FXR [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 4sc-101; SC12267. CAS No. 717824-30-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14908.
Vidupiprant
This active molecular is a potent and selective D-prostanoid and CRTH2 inhibitor. IC50 values are 8 and 35 nM, respectively in plasma. Vidupiprant as an add-on to inhaled corticosteroid therapy demonstrated no associated risks but was not effective at improving asthma symptoms or lung function in patients with inadequately controlled moderate-to-severe asthma.symptoms or lung function in patients with inadequately controlled moderate-to-severe asthma. Uses: Asthma. Synonyms: 2-[4-[4- (tert-butylcarbamoyl) -2-[ (2-chloro-4-cyclopropylphenyl) sulfonylamino]phenoxy]-5-chloro-2-fluorophenyl]aceticacid; VIDUPIPRANT; UNII-61OTZ32XNC; CHEMBL1951575; CHEMBL 1951575; CHEMBL-1951575; AMG853; AMG 853; AMG-853; 1169483-24-2. Grades: 98%. CAS No. 1169483-24-2. Molecular formula: C28H27Cl2FN2O6S. Mole weight: 609.49.
Vigabatrin
Vigabatrin. Group: Biochemicals. Grades: Purified. CAS No. 60643-86-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Vigabatrin (γ-Vinyl-GABA), an inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: γ-Vinyl-GABA. CAS No. 68506-86-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15399.
Vigabatrin
Vigabatrin is an analogue of gamma-aminobutyric acid(GABA) and is an irreversible inhibitor of 4-aminobutyrate transaminase. It is used in combination with other agents as therapy of refractory complex partial seizures and as monotherapy for infantile spasms. It is an antiepileptic drug that inhibits the breakdown of GABA by acting as a suicide inhibitor of GABA transaminase (GABA-T). It increases brain concentrations of GABA, an inhibitory neurotransmitter in the CNS, by irreversibly inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings. It may also work by suppressing repetitive neuronal firing through inhibition of voltage-sensitive sodium channels. It is a racemic compound, and its [S]-enantiomer is pharmacologically active. It has been listed. Uses: Vigabatrin is used in combination with other agents as therapy of refractory complex partial seizures and as monotherapy for infantile spasms. it is an antiepileptic drug. Synonyms: γ-Vinyl-GABA; 4-Amino-5-hexenoic Acid; (±)-4-Amino-5-hexenoic Acid; Sabril; Vigabatrine; 4-Aminohexenoic acid; rac-Vigabatrin; (±)-Vigabatrin; (±)-4-Aminohexenoic acid. Grades: ≥98%. CAS No. 68506-86-5. Molecular formula: C6H11NO2. Mole weight: 129.16.
Vigabatrin EP Impurity A
An impurity of Vigabatrin. Vigabatrin is an inhibitor of the enzyme GABA transaminase (GABA-T) used as an antiepileptic drug. Synonyms: 5-Ethenyl-2-pyrrolidinone; 5-Vinyl-2-pyrrolidinone; (±)-5-Vinylpyrrolidin-2-one; 5-Vinyl-2-pyrrolidinone; MDL 17637-03. CAS No. 7529-16-0. Molecular formula: C6H9NO. Mole weight: 111.14.
Vigabatrin EP Impurity A
Vigabatrin EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 7529-16-0. Molecular Formula: C6H9NO. Mole Weight: 111.14. Catalog: APB7529160.
Vigabatrin EP Impurity B
An impurity of Vigabatrin. Vigabatrin is an inhibitor of the enzyme GABA transaminase (GABA-T) used as an antiepileptic drug. Synonyms: UNII-6GON7WT3C8; (2E)-2-(2-Aminoethyl)but-2-enoic acid; 2-(2-Aminoethyl)but-2-enoic acid, (2E)-; 6GON7WT3C8; (E)-2-(2-aminoethyl)but-2-enoic acid. CAS No. 1379504-35-4. Molecular formula: C6H11NO2. Mole weight: 129.16.
Vigabatrin EP Impurity B
Vigabatrin EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1379504-35-4. Molecular Formula: C6H11NO2. Mole Weight: 129.16. Catalog: APB1379504354.
Vigabatrin EP Impurity B HCl
Vigabatrin EP Impurity B HCl. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1379403-11-8. Molecular Formula: C6H12ClNO2. Mole Weight: 165.62. Catalog: APB1379403118.
Vigabatrin EP Impurity C
Vigabatrin EP Impurity C is used in the synthesis of diaminoalkenes through copper-mediated diamination reaction. Synonyms: 2-Oxo-5-vinylpyrrolidine-3-carboxamide; 5-Ethenyl-2-oxo-3-pyrrolidinecarboxamide. Molecular formula: C7H10N2O2. Mole weight: 154.17.
Vigabatrin EP Impurity C
Vigabatrin EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 71107-19-2. Molecular Formula: C7H10N2O2. Mole Weight: 154.17. Catalog: APB71107192.
Vigabatrin EP Impurity D
Vigabatrin EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 56-12-2. Molecular Formula: C4H9NO2. Mole Weight: 103.12. Catalog: APB56122.
Vigabatrin EP Impurity E
Vigabatrin EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1378466-25-1. Molecular Formula: C7H11NO4. Mole Weight: 173.17. Catalog: APB1378466251.
Vigabatrin EP Impurity E
Vigabatrin EP Impurity E is a derivative of Vigabatrin. Vigabatrin is an inhibitor of the enzyme GABA transaminase (GABA-T) used as an antiepileptic drug. Synonyms: 2-(2-Aminobut-3-enyl)malonic Acid. CAS No. 1378466-25-1. Molecular formula: C7H11NO4. Mole weight: 173.17.
Vigabatrin EP Impurity F
An impurity of Vigabatrin. Vigabatrin is an inhibitor of the enzyme GABA transaminase (GABA-T) used as an antiepileptic drug. Synonyms: 4-(4-Amino-hex-5-enoylamino)-hex-5-enoic Acid; 4-[(4-Amino-1-oxo-5-hexenyl)amino]-5-hexenoic Acid; 4-[(4-Amino-1-oxo-5-hexen-1-yl)amino]-5-hexenoic Acid. CAS No. 794466-81-2. Molecular formula: C12H20N2O3. Mole weight: 240.3.
Vigabatrin EP Impurity F
Vigabatrin EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 794466-81-2. Molecular Formula: C12H20N2O3. Mole Weight: 240.3. Catalog: APB794466812.
A selective, irreversible inhibitor of GABA transaminase with antiepileptic properties. Covalently binds to the active site of GABA tansaminase to inactivate it in a dose-dependent manner and increases extracellular GABA levels in the brain. Rapidly absorbed following oral administration and is shown to inhibit [3H]GABA uptake across the apical membrane of Caco-2 cell monolayers in a concentration-dependent manner (IC50 = 2.9mM). Group: Biochemicals. Grades: Highly Purified. CAS No. 68506-86-5. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Vigabatrin hydrochloride
Vigabatrin hydrochloride (γ-Vinyl-GABA hydrochloride), a inhibitory neurotransmitter GABA vinyl-derivative, is an orally active and irreversible GABA transaminase inhibitor. Vigabatrin hydrochloride is an antiepileptic agent, which acts by increasing GABA levels in the brain by inhibiting the catabolism of GABA by GABA transaminase [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: γ-Vinyl-GABA hydrochloride. CAS No. 1391054-02-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B0033.