American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

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Product
Vitamin K-d7 (5,6,7,8-d4, 2-methyl-d3) 99 atom % D, 97% (CP Sum of E & Z Isomers). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
vitamin-K-epoxide reductase (warfarin-insensitive) Vitamin K 2,3-epoxide is reduced to 3-hydroxy- (and 2-hydroxy-) vitamin K by 1,4-dithiothreitol, which is oxidized to a disulfide. Not inhibited by warfarin [cf. EC 1.17.4.4, vitamin-K-epoxide reductase (warfarin-sensitive)]. Group: Enzymes. Enzyme Commission Number: EC 1.17.4.5. CAS No. 97089-80-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1093; vitamin-K-epoxide reductase (warfarin-insensitive); EC 1.17.4.5; 97089-80-0. Cat No: EXWM-1093. Creative Enzymes
vitamin-K-epoxide reductase (warfarin-sensitive) Vitamin K 2,3-epoxide is reduced to vitamin K and possibly to vitamin K hydroquinone by 1,4-dithiothreitol, which is oxidized to a disulfide; some other dithiols and 4-butanethiol can also act. Inhibited strongly by warfarin [cf. EC 1.17.4.5, vitamin-K-epoxide reductase (warfarin-insensitive)]. Group: Enzymes. Enzyme Commission Number: EC 1.17.4.4. CAS No. 55963-40-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1092; vitamin-K-epoxide reductase (warfarin-sensitive); EC 1.17.4.4; 55963-40-1. Cat No: EXWM-1092. Creative Enzymes
Vitamin P4 Liposome Vitamin P4, also known as Troxerutin, inhibits platelet aggregation, prevents thrombus formation, improves blood circulation, increases capillary resistance, treats acute ischemic brain injury, and helps improve certain vascular disorders in the body. This product is a pre-formulated liposome encapsulating Vitamin P4. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. Creative Biolabs
Vitamins - IR Identification PT Proficiency Testing Material. Group: Atomic absorption spectroscopy (aas). Alfa Chemistry Analytical Products
Vitamin U chloride Vitamin U (S-Methylmethionine sulfonium) chloride is an orally active anti-ulcer agent with antioxidant activity. Vitamin U inhibits adipocyte differentiation. Vitamin U promotes skin wound healing.Vitamin U can be used in the research of gastrointestinal ulceration [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: S-Methylmethionine sulfonium chloride. CAS No. 1115-84-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N2551. MedChemExpress MCE
Vitexin 8-(β-D-Glucopyranosyl)-4,5,7-trihydroxyflavone. CAS No. 3681-93-4. Product ID: 8-05147. Molecular formula: C21H20O10. Mole weight: 432.38. Properties: Apigenin flavone glucoside. CarboMer Inc
Vitexin Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 3681-93-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0013. MedChemExpress MCE
Vitexin Vitexin. Group: Biochemicals. Alternative Names: 8-Glucopyranosyl apigenin; 8-Glucosylapigenin; Orientoside. Grades: Plant Grade. CAS No. 3681-93-4. Pack Sizes: 20mg. Molecular Formula: C21H20O10, Molecular Weight: 432.377999999999. US Biological Life Sciences. USBiological 9
Worldwide
Vitexin 2''-O-p-coumarate Vitexin 2''-O-p-coumarate. Group: Biochemicals. Grades: Plant Grade. CAS No. 59282-55-2. Pack Sizes: 5mg. Molecular Formula: C30H26O12, Molecular Weight: 578.53. US Biological Life Sciences. USBiological 9
Worldwide
Vitexin 2''-O-p-coumarate Vitexin 2''-O-p-coumarate is a compound of the flavonoid class isolated from the seeds of Trigonella foenum-graecum. Vitexin 2''-O-p-coumarate promotes 2BS cell proliferation induced by H(2)O(2). Synonyms: [(2S,3R,4S,5S,6R)-2-[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-8-yl]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl] 3-(4-hydroxyphenyl)prop-2-enoate. Grades: >98%. CAS No. 59282-55-2. Molecular formula: C30H26O12. Mole weight: 578.526. BOC Sciences 9
Vitexin 2''-O-rhamnoside Vitexin 2''-O-rhamnoside. Group: Biochemicals. CAS No. 64820-99-1. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 9
Worldwide
Vitexin-2'-O-rhamnoside Vitexin-2"-O-rhamnoside, a main flavonoid glycoside of the leaves of Cratagus pinnatifida Bge, contributes to the protection against H 2 O 2 -mediated oxidative stress damage and has potential to treat cardiovascular system diseases [1]. Uses: Scientific research. Group: Natural products. CAS No. 64820-99-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0534. MedChemExpress MCE
vitexin 2''-O-rhamnoside 7-O-methyltransferase The flavonoids vitexin and isovitexin 2''-O-arabinoside do not act as substrates for the enzyme from oats (Avena sativa). Group: Enzymes. Enzyme Commission Number: EC 2.1.1.153. CAS No. 90698-29-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1749; vitexin 2''-O-rhamnoside 7-O-methyltransferase; EC 2.1.1.153; 90698-29-6. Cat No: EXWM-1749. Creative Enzymes
Vitexin-2-O-rhamnoside (Rhamnosylvitexin, 2"-Rhamnosylvitexin) Vitexin-2-O-rhamnoside (Rhamnosylvitexin, 2"-Rhamnosylvitexin). Group: Biochemicals. Alternative Names: Vitexin 2''-o-rhamnoside. Grades: Plant Grade. CAS No. 64820-99-1. Pack Sizes: 20mg. Molecular Formula: C27H30O14, Molecular Weight: 578.519. US Biological Life Sciences. USBiological 9
Worldwide
Vitexin 4''-O-glucoside Vitexin 4''-O-glucoside. Group: Biochemicals. CAS No. 178468-00-3. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 9
Worldwide
Vitexin-4''-O-glucoside Vitexin-4''-O-glucoside is a flavonoid isolated from Crataegus pinnatifida Bunge. Synonyms: 4''-O-Glucosylvitexin; Vitexin 4''-O-glucoside. Grades: 98%. CAS No. 178468-00-3. Molecular formula: C27H30O15. Mole weight: 594.5. BOC Sciences 9
Vitexin-4''-O-glucoside Vitexin-4''-O-glucoside is a kind of flavonoid fraction from the leaves of Crataegus pinnatifida [1]. Uses: Scientific research. Group: Natural products. Alternative Names: 4''-O-Glucosylvitexin. CAS No. 178468-00-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N5073. MedChemExpress MCE
Vitexin-4-rhamnoside Vitexin-4-rhamnoside is a potent bioactive compound widely used in the biomedical industry. Derived from natural sources, it has been shown to exhibit strong anti-inflammatory and antioxidant properties. This product is commonly employed in the treatment of various diseases such as cancer, cardiovascular disorders, and neurodegenerative conditions. Its therapeutic potential makes it a valuable asset in drug development and disease management within the field of biomedicine. Synonyms: Vitexin rhamnoside; 32426-34-9; 5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-2-[4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyphenyl]chromen-4-one; Vitexin-4'-Rhamnoside; EINECS 251-036-0; 8-glycosyl-apigenin-rhamnoside; CHEMBL1685071; DTXSID00186171; CHEBI:189451; 2-(4-((6-Deoxy-alpha-L-mannopyranosyl)oxy)phenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy-4H-benzopyran-4-one. CAS No. 32426-34-9. Molecular formula: C27H30O14. Mole weight: 578.5. BOC Sciences 12
Vitexin Argininate Vitexin Argininate. Group: Biochemicals. Grades: Plant Grade. CAS No. Pack Sizes: 20mg. US Biological Life Sciences. USBiological 9
Worldwide
vitexin β-glucosyltransferase Vitexin is a flavonoid from Cannabis sativa (hemp) and some populations of Silene alba. Group: Enzymes. Synonyms: uridine diphosphoglucose-vitexin 2''-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.105. CAS No. 76828-68-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2333; vitexin β-glucosyltransferase; EC 2.4.1.105; 76828-68-7; uridine diphosphoglucose-vitexin 2''-glucosyltransferase. Cat No: EXWM-2333. Creative Enzymes
Viton Powder Viton Powder. Group: other nano materials. CAS No. 19011-17-0. Molecular formula: 233.04 g/mol. 99.9%. Alfa Chemistry Materials 2
Vitronectin from human plasma, solution, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
Vitronectin from bovine plasma lyophilized powder, BioReagent, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
Vitronectin from human plasma lyophilized powder, BioReagent, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
Vitronectin from rat plasma lyophilized powder, BioReagent, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
Vitronectin human recombinant, expressed in HEK 293 cells, ?95% (SDS-PAGE), ?95% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
Vixarelimab Vixarelimab (KPL-716) is a human anti-oncostatin M ( OSM ) monoclonal antibody that binds to the beta chain of the OSM receptor and inhibits IL-31 and OSM signalling. Vixarelimab can be used in studies of inflammatory skin diseases such as atopic dermatitis and itchy nodular rash [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: KPL-716. CAS No. 2243320-83-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99519. MedChemExpress MCE
VJ115 VJ115 is a novel chemical entity that inhibits the enzyme ENOX1, a NADH oxidase. Genetic and small molecule inhibition of ENOX1 inhibits endothelial cell tubule formation and tumor-mediated neo-angiogenesis. VJ115 inhibition of ENOX1 can impact expression of proteins involved in cytoskeletal reorganization and support a hypothesis in which ENOX1 activity links elevated cellular NADH concentrations with cytoskeletal reorganization and angiogenesis. Synonyms: VJ 115; VJ-115; (Z)-2-((1-benzyl-1H-indol-3-yl)methylene)quinuclidin-3-ol. CAS No. 929256-79-1. Molecular formula: C23H24N2O. Mole weight: 344.45. BOC Sciences 11
VJDT VJDT is a TREM1 inhibitor that can effectively block TREM1 signaling. VJDT inhibits tumor cell proliferation and migration and induces cell cycle arrest. VJDT has immunomodulatory and antitumor activities, and can be used for the research of tumors such as melanoma[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2765319-65-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157122. MedChemExpress MCE
VK-2019 VK-2019 is an oral active, selective EBNA1 ((Epstein-Barr Nuclear Antigen 1) inhibitor and can be used for study of EBV-associated carcinomas [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2044520-06-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W725179. MedChemExpress MCE
VK-28 VK-28, a brain-permeable iron chelator, inhibits both basal and Fe/ascorbate-induced mitochondrial membrane lipid peroxidation, with an IC 50 of 12.7 μM. VK-28 exhibits significant neuroprotective effects on ICV-6-OHDA. VK-28 can be used for the research of Parkinsons disease and other neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 312611-92-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W686216. MedChemExpress MCE
VK3-OCH3 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
VKGILS-NH2 VKGILS-NH2. Group: Biochemicals. Grades: Purified. CAS No. 942413-05-0. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 5
Worldwide
VKGILS-NH2 VKGILS-NH2 is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 has no effect on DNA synthesis in cells [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 942413-05-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1310. MedChemExpress MCE
VKGILS-NH2 VKGILS-NH2 is a reversed control peptide for SLIGKV-NH2, which is a protease-activated receptor 2 (PAR2) agonist. Synonyms: retro-PAR-2 (1-6) amide (human); retro-SLIGKVamide; Thrombin Receptor-Like 1 (6-1) amide (human); Proteinase Activated Receptor 2 (6-1) amide (human); PAR-2 (6-1) amide (human). Grades: 98%. CAS No. 942413-05-0. Molecular formula: C28H54N8O7. Mole weight: 614.79. BOC Sciences 8
VKGILS-NH2 acetate VKGILS-NH2 acetate is a reversed control peptide for SLIGKV-NH2, which is a protease-activated receptor 2 (PAR2) agonist. Synonyms: H-Val-Lys-Gly-Ile-Leu-Ser-NH2.CH3CO2H; L-valyl-L-lysyl-glycyl-L-isoleucyl-L-leucyl-L-serinamide acetic acid. Grades: ≥95%. CAS No. 2763585-10-8. Molecular formula: C28H54N8O7.C2H4O2. Mole weight: 674.83. BOC Sciences 6
VLS-1272 VLS-1272 (Compound 22) is an orally active KIF18A inhibitor that binds to the KIF18A-microtubule complex in an ATP-noncompetitive manner (IC50 = 41 nM), blocking its ATPase activity and inhibiting microtubule translocation. This leads to abnormal accumulation of KIF18A at spindle poles, disrupting chromosome alignment and inducing mitotic arrest and apoptosis in CINHigh tumor cells (e.g., ovarian cancer OVCAR-3, breast cancer JIMT-1). VLS-1272 is a promising candidate for anti-tumor research[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KIF18A-IN-7. CAS No. 2914878-00-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153066. MedChemExpress MCE
VLX1570 VLX1570 is a competitive inhibitor of proteasome deubiquitinases (DUBs) with an IC50 of approximate 10 ?M. Uses: Scientific research. Group: Signaling pathways. CAS No. 1431280-51-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12471. MedChemExpress MCE
VLX600 VLX600 is an iron-chelating inhibitor of oxidative phosphorylation (OXPHOS). VLX600 causes mitochondrial dysfunction and induces a strong shift to glycolysis. VLX600 displays selective cytotoxic activity against malignant cell and induces autophagy. Anticancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 327031-55-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-12406. MedChemExpress MCE
VM&P Naptha VM & P Naptha. Category ALIPHATIC SOLVENTS. Pack Sizes Bulk/ Drums CJ Chemicals
VMY-1-103 VMY-1-103 is a potent CDK inhibitor, is also a novel dansylated analog of purvalanol B, was shown to inhibit cell cycle progression and proliferation in prostate and breast cancer cells more effectively than purvalanol B. VMY-1-103 increased the sub G(1) fraction of apoptotic cells, induced PARP and caspase-3 cleavage and increased the levels of the Death Receptors DR4 and DR5, Bax and Bad while decreasing the number of viable cells, all supporting apoptosis as a mechanism of cell death. VMY-1-103 possesses unique antiproliferative capabilities and that this compound may form the basis of a new candidate drug to treat medulloblastoma. Synonyms: VMY1-103; VMY 1-103. Grades: 98%. CAS No. 1209002-43-6. Molecular formula: C34H42ClN9O4S. Mole weight: 708.28. BOC Sciences 11
VNbAlC (MAX) Phase Ceramic Materials VNbAlC (MAX) Phase Ceramic Materials. Uses: High temperature coating, mxene precursor, conductive self-lubricating ceramic, lithiumionbattery, super capacitor, electrochemical catalysis. Group: Mxene materials. >90%. Alfa Chemistry Materials 3
Vne I One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. G↑TGCAC CACGT↓G. Activity: 10000-20000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene VneI from Vibrio nereis 18. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1186RE. Creative Enzymes
VNPB VNPB. Group: Organic light-emitting diode (oled) materials. Alternative Names: N4,N4'-di(Naphthalen-1-yl)-N4,N4'-bis(4- vinylphenyl)biphenyl-4,4'-diamine. CAS No. 1010396-31-2. Product ID: N-[4-[4-(4-ethenyl-N-naphthalen-1-ylanilino)phenyl]phenyl]-N-(4-ethenylphenyl)naphthalen-1-amine. Molecular formula: 640.81. Mole weight: C48H36N2. C=CC (C=C1)=CC=C1N (C2=CC=CC3=C2C=CC=C3)C (C=C4)=CC=C4C5=CC=C (N (C6=CC=C (C=C)C=C6)C7=CC=CC8=C7C=CC=C8)C=C5. 1S/C48H36N2/c1-3-35-19-27-41 (28-20-35) 49 (47-17-9-13-39-11-5-7-15-45 (39) 47) 43-31-23-37 (24-32-43) 38-25-33-44 (34-26-38) 50 (42-29-21-36 (4-2) 22-30-42) 48-18-10-14-40-12-6-8-16-46 (40) 48/h3-34H, 1-2H2, WTEWXIOJLNVYBZ-UHFFFAOYSA-N. WTEWXIOJLNVYBZ-UHFFFAOYSA-N. Alfa Chemistry Materials 4
Voacamine Voacamine, an indole alkaloid, exhibits potent cannabinoid CB1 receptor antagonistic activity [1]. Voacamine also inhibits P-glycoprotein ( P-gp ) action in multidrug-resistant tumor cells [1]. Uses: Scientific research. Group: Natural products. CAS No. 3371-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6932. MedChemExpress MCE
Voacamine Botanical Source: Group: Biochemicals. Alternative Names: Voacanginine. Grades: Plant Grade. CAS No. 3371-85-5. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 9
Worldwide
Voacamine Voacamine is an alkaloid originally isolated from Voacanga. It is a cannabinoid receptor 1 (CB1) antagonist with IC50 value of 41 nM. It has been approved as an antimalarial drug in several African countries. It is also under investigation for modulating multidrug-resistance in tumor cells. Synonyms: NSC 82591; Voacanginine. Grades: ≥98%. CAS No. 3371-85-5. Molecular formula: C43H52N4O5. Mole weight: 704.90. BOC Sciences 10
Voacangine Voacangine is an antagonist for TRPV1 and TRPM8 but as an agonist for TRPA1 ( EC 50 =8 μM). Voacangine competitively blockes capsaicin binding to TRPV1 ( IC 50 =50 μM). Voacangine competitively inhibits the binding of menthol to TRPM8 ( IC 50 =9 μM) and it shows noncompetitive inhibition against icilin ( IC 50 =7 μM). Voacangine selectively abrogates chemical agonist-induced TRPM8 activation and did not affect cold-induced activation. Voacangine is an alkaloid isolated from the root bark of Voacanga africana [1]. Uses: Scientific research. Group: Natural products. CAS No. 510-22-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7536. MedChemExpress MCE
Voacangine Voacangine is a kind of alkaloid and has been found to exhibit anti-addictive properties. Synonyms: (-)-Voacangine; Carbomethoxyibogaine; 12-Methoxyibogamine-18-carboxylic acid methyl ester. CAS No. 510-22-5. Molecular formula: C22H28N2O3. Mole weight: 368.48. BOC Sciences 7
VOAS in Soil - Low Level - PT Proficiency Testing Material. Group: Atomic absorption spectroscopy (aas). Alfa Chemistry Analytical Products
VOAs in Soil - Medium Level certified reference material. Group: Certified reference materials (crms). Alfa Chemistry Analytical Products
VOAs in Soil - Medium Level - PT Proficiency Testing Material. Group: Atomic absorption spectroscopy (aas). Alfa Chemistry Analytical Products
Vobarilizumab Vobarilizumab (ALX-0061) is a humanized bispecific anti- IL-6R and anti-human serum albumin (ALB) monoclonal antibody (mAb) ( K d : 0.19 pM). Vobarilizumab consists of an anti-IL-6R domain and an anti-human serum albumin domain. Vobarilizumab can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ALX-0061. CAS No. 1628814-88-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99385. MedChemExpress MCE
Vobramitamab Vobramitamab is a humanized B7-H3 monoclonal antibody (mAb). Vobramitamab conjugated with prodrug seco-DUBA (HY-132180A) via a cleavable linker, to form antibody-drug conjugate (ADC), the MGC018. MGC018 displays potent antitumor activity in preclinical tumor models of breast, ovarian, and lung cancer, as well as melanoma [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AEX-4089. CAS No. 2490556-50-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99101. MedChemExpress MCE
Vociprotafib Vociprotafib (RMC-4630) is an orally active, selective and potent phosphatase SHP2 inhibitor, which blocks activation of the RAS-RAF-MEK-ERK signaling pathway with antitumor activity. Vociprotafib accelerates the time to, and increases the magnitude of, tumor regressions in Osimertinib (HY-15772)-sensitive EGFR-mutant tumors of mice[1][2][3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RMC-4630; SHP2-IN-7. CAS No. 2172652-48-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141523. MedChemExpress MCE
Voclosporin Voclosporin (ISAtx-247) is a calcineurin (PP2B) (CN) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ISAtx-247. CAS No. 515814-01-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106638. MedChemExpress MCE
Voclosporine Voclosporine is an orally available calcineurin inhibitor and potent immunosuppressant used in combination with mycophenolate mofetil and corticosteroids for the treatment of acute lupus nephritis. Uses: A new agent for the treatment of noninfectious uveitis. uveitis is an inflammatory, putative th1-mediated autoimmune disease that affects various parts of the eye and is a leading cause of visual loss. voclosporin, a rationally designed novel calcineurin. Synonyms: 6-[(2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic acid]cyclosporin A; ISATX 247; R 1524; trans-ISA 247; Voclosporin; Luveniq; Lupkynis; 1,11-anhydro[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-[(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)nona-6,8-dienoyl][(2S)-2-aminobutanoyl]-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucine]. Grades: >98%. CAS No. 515814-01-4. Molecular formula: C63H111N11O12. Mole weight: 1214.62. BOC Sciences 8
VOCs - Clay 4 certified reference material, pkg of 25 g. Group: Certified reference materials (crms). Alfa Chemistry Analytical Products
VOCs - Loamy Sand 4 pkg of 30 g. Group: Certified reference materials (crms). Alfa Chemistry Analytical Products
VOCs - Loamy Sand 5 certified reference material, pkg of 25 g. Group: Certified reference materials (crms). Alfa Chemistry Analytical Products
VOCs - Sandy Loam 1 pkg of 25 g. Group: Certified reference materials (crms). Alfa Chemistry Analytical Products
VOCs - Sediment 2 certified reference material, pkg of 25 g. Group: Certified reference materials (crms). Alfa Chemistry Analytical Products
Vodobatinib Vodobatinib (K0706) is a potent, third generation and orally active Bcr-Abl1 tyrosine kinase inhibitor with an IC50 of 7 nM. Vodobatinib exhibits activity against most BCR-ABL1 point mutants, and has no activity against BCR-ABL1T315I. Vodobatinib can be used for chronic myeloid leukemia (CML) research[1][2]. Vodobatinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: K0706. CAS No. 1388803-90-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137460. MedChemExpress MCE
Vofopitant Vofopitant is potent tachykinin NK 1 receptor antagonist, with pK i s of 10.6, 9.5, and 9.8 for human, rat and ferret NK 1 receptor, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 205171. CAS No. 168266-90-8. Pack Sizes: 5 mg. Product ID: HY-12142. MedChemExpress MCE
Vofopitant dihydrochloride Vofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist, inhibits [ 3 H]SP binding to the NK1 receptor with pK i values of 9.5 and 10.6 in rat and human membranes respectively, acts as a potential broad-spectrum anti-emetic agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 205171A. CAS No. 168266-51-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12143. MedChemExpress MCE
Vofopitant Dihydrochloride The dihydrochloride salt form of Vofopitant, a tetrazole compound, has been found to be a neurokinin 1 antagonist that was once studied inbBipolar disorders as well as nausea and vomiting. Synonyms: Vofopitant dihydrochloride; 3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluoro-methyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-, dihydrochloride, (2S,3S)-;3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-, dihy. Grades: 98%. CAS No. 168266-51-1. Molecular formula: C21H23F3N6O2HCl. Mole weight: 505.37. BOC Sciences 9
Voglibose Voglibose is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various disorders caused by hyperglycemia. Uses: Hypoglycemic agents. Synonyms: 3,4-Dideoxy-[2-hydroxy-1-(hydroxyethyl)ethyl] amino-1-C-(hydroxynethyl)-1,2,3,4-cyclohexaneterol; 3,4-Dideoxy-4-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-C-(hydroxymethyl)-D-epiinositol. Grades: >98%. CAS No. 83480-29-9. Molecular formula: C10H21NO7. Mole weight: 267.28. BOC Sciences 11
Voglibose Voglibose is an orally active alpha-glucosidase inhibitor that prevents the development of colorectal precancerous lesions induced by obesity and diabetes. Voglibose reduces oxidative stress in an inflammatory environment and inhibits the insulin-like growth factor/insulin-like growth factor-1 receptor (IGF/IGF-1R) functional axis [1]. Uses: Scientific research. Group: Natural products. CAS No. 83480-29-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0025. MedChemExpress MCE
Voglibose Voglibose. Group: Biochemicals. Grades: Purified. CAS No. 83480-29-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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