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| Product | Description | |
|---|---|---|
| VK3-OCH3 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| VKGILS-NH2 | VKGILS-NH2 is a reversed amino acid sequence control peptide for SLIGKV-NH2 (protease-activated receptor 2 (PAR2) agonist). VKGILS-NH2 has no effect on DNA synthesis in cells [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 942413-05-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1310. |  |
| VKGILS-NH2 | VKGILS-NH2 is a reversed control peptide for SLIGKV-NH2, which is a protease-activated receptor 2 (PAR2) agonist. Synonyms: retro-PAR-2 (1-6) amide (human); retro-SLIGKVamide; Thrombin Receptor-Like 1 (6-1) amide (human); Proteinase Activated Receptor 2 (6-1) amide (human); PAR-2 (6-1) amide (human). Grades: 98%. CAS No. 942413-05-0. Molecular formula: C28H54N8O7. Mole weight: 614.79. |  |
| VKGILS-NH2 | VKGILS-NH2. Group: Biochemicals. Grades: Purified. CAS No. 942413-05-0. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| VKGILS-NH2 acetate | VKGILS-NH2 acetate is a reversed control peptide for SLIGKV-NH2, which is a protease-activated receptor 2 (PAR2) agonist. Synonyms: H-Val-Lys-Gly-Ile-Leu-Ser-NH2.CH3CO2H; L-valyl-L-lysyl-glycyl-L-isoleucyl-L-leucyl-L-serinamide acetic acid. Grades: ≥95%. CAS No. 2763585-10-8. Molecular formula: C28H54N8O7.C2H4O2. Mole weight: 674.83. | |
| VLX600 | VLX600 is an iron-chelating inhibitor of oxidative phosphorylation (OXPHOS). VLX600 causes mitochondrial dysfunction and induces a strong shift to glycolysis. VLX600 displays selective cytotoxic activity against malignant cell and induces autophagy. Anticancer activity [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 327031-55-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-12406. | |
| VM&P Naptha | VM & P Naptha. Category ALIPHATIC SOLVENTS. Pack Sizes Bulk/ Drums |  |
| VMY-1-103 | VMY-1-103 is a potent CDK inhibitor, is also a novel dansylated analog of purvalanol B, was shown to inhibit cell cycle progression and proliferation in prostate and breast cancer cells more effectively than purvalanol B. VMY-1-103 increased the sub G(1) fraction of apoptotic cells, induced PARP and caspase-3 cleavage and increased the levels of the Death Receptors DR4 and DR5, Bax and Bad while decreasing the number of viable cells, all supporting apoptosis as a mechanism of cell death. VMY-1-103 possesses unique antiproliferative capabilities and that this compound may form the basis of a new candidate drug to treat medulloblastoma. Synonyms: VMY1-103; VMY 1-103. Grades: 98%. CAS No. 1209002-43-6. Molecular formula: C34H42ClN9O4S. Mole weight: 708.28. | |
| VNbAlC (MAX) Phase Ceramic Materials | VNbAlC (MAX) Phase Ceramic Materials. Uses: High temperature coating, mxene precursor, conductive self-lubricating ceramic, lithiumionbattery, super capacitor, electrochemical catalysis. Group: Mxene materials. >90%. |  |
| Vne I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. G↑TGCAC CACGT↓G. Activity: 10000-20000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene VneI from Vibrio nereis 18. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1186RE. |  |
| VNPB | VNPB. Group: Organic light-emitting diode (oled) materials. Alternative Names: N4,N4'-di(Naphthalen-1-yl)-N4,N4'-bis(4- vinylphenyl)biphenyl-4,4'-diamine. CAS No. 1010396-31-2. Product ID: N-[4-[4-(4-ethenyl-N-naphthalen-1-ylanilino)phenyl]phenyl]-N-(4-ethenylphenyl)naphthalen-1-amine. Molecular formula: 640.81. Mole weight: C48H36N2. C=CC (C=C1)=CC=C1N (C2=CC=CC3=C2C=CC=C3)C (C=C4)=CC=C4C5=CC=C (N (C6=CC=C (C=C)C=C6)C7=CC=CC8=C7C=CC=C8)C=C5. 1S/C48H36N2/c1-3-35-19-27-41 (28-20-35) 49 (47-17-9-13-39-11-5-7-15-45 (39) 47) 43-31-23-37 (24-32-43) 38-25-33-44 (34-26-38) 50 (42-29-21-36 (4-2) 22-30-42) 48-18-10-14-40-12-6-8-16-46 (40) 48/h3-34H, 1-2H2, WTEWXIOJLNVYBZ-UHFFFAOYSA-N. WTEWXIOJLNVYBZ-UHFFFAOYSA-N. | |
| Voacamine | Voacamine is an alkaloid originally isolated from Voacanga. It is a cannabinoid receptor 1 (CB1) antagonist with IC50 value of 41 nM. It has been approved as an antimalarial drug in several African countries. It is also under investigation for modulating multidrug-resistance in tumor cells. Synonyms: NSC 82591; Voacanginine. Grades: ≥98%. CAS No. 3371-85-5. Molecular formula: C43H52N4O5. Mole weight: 704.90. | |
| Voacamine | Voacamine, an indole alkaloid, exhibits potent cannabinoid CB1 receptor antagonistic activity [1]. Voacamine also inhibits P-glycoprotein ( P-gp ) action in multidrug-resistant tumor cells [1]. Uses: Scientific research. Group: Natural products. CAS No. 3371-85-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6932. | |
| Voacamine | Botanical Source: Group: Biochemicals. Alternative Names: Voacanginine. Grades: Plant Grade. CAS No. 3371-85-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Voacangine | Voacangine is a kind of alkaloid and has been found to exhibit anti-addictive properties. Synonyms: (-)-Voacangine; Carbomethoxyibogaine; 12-Methoxyibogamine-18-carboxylic acid methyl ester. CAS No. 510-22-5. Molecular formula: C22H28N2O3. Mole weight: 368.48. | |
| Voacangine | Voacangine is an antagonist for TRPV1 and TRPM8 but as an agonist for TRPA1 ( EC 50 =8 μM). Voacangine competitively blockes capsaicin binding to TRPV1 ( IC 50 =50 μM). Voacangine competitively inhibits the binding of menthol to TRPM8 ( IC 50 =9 μM) and it shows noncompetitive inhibition against icilin ( IC 50 =7 μM). Voacangine selectively abrogates chemical agonist-induced TRPM8 activation and did not affect cold-induced activation. Voacangine is an alkaloid isolated from the root bark of Voacanga africana [1]. Uses: Scientific research. Group: Natural products. CAS No. 510-22-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7536. | |
| VOAS in Soil - Low Level - PT | Proficiency Testing Material. Group: Atomic absorption spectroscopy (aas). | |
| VOAs in Soil - Medium Level | certified reference material. Group: Certified reference materials (crms). | |
| VOAs in Soil - Medium Level - PT | Proficiency Testing Material. Group: Atomic absorption spectroscopy (aas). | |
| Vobarilizumab | Vobarilizumab (ALX-0061) is a humanized bispecific anti- IL-6R and anti-human serum albumin (ALB) monoclonal antibody (mAb) ( K d : 0.19 pM). Vobarilizumab consists of an anti-IL-6R domain and an anti-human serum albumin domain. Vobarilizumab can be used in the research of inflammatory autoimmune diseases, such as rheumatoid arthritis [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: ALX-0061. CAS No. 1628814-88-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99385. | |
| Vobramitamab | Vobramitamab is a humanized B7-H3 monoclonal antibody (mAb). Vobramitamab conjugated with prodrug seco-DUBA (HY-132180A) via a cleavable linker, to form antibody-drug conjugate (ADC), the MGC018. MGC018 displays potent antitumor activity in preclinical tumor models of breast, ovarian, and lung cancer, as well as melanoma [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: AEX-4089. CAS No. 2490556-50-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99101. | |
| Voclosporin | Voclosporin (ISAtx-247) is a calcineurin (PP2B) (CN) inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ISAtx-247. CAS No. 515814-01-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106638. | |
| Voclosporine | Voclosporine is an orally available calcineurin inhibitor and potent immunosuppressant used in combination with mycophenolate mofetil and corticosteroids for the treatment of acute lupus nephritis. Uses: A new agent for the treatment of noninfectious uveitis. uveitis is an inflammatory, putative th1-mediated autoimmune disease that affects various parts of the eye and is a leading cause of visual loss. voclosporin, a rationally designed novel calcineurin. Synonyms: 6-[(2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic acid]cyclosporin A; ISATX 247; R 1524; trans-ISA 247; Voclosporin; Luveniq; Lupkynis; 1,11-anhydro[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-[(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)nona-6,8-dienoyl][(2S)-2-aminobutanoyl]-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucine]. Grades: >98%. CAS No. 515814-01-4. Molecular formula: C63H111N11O12. Mole weight: 1214.62. | |
| VOCs - Clay 4 | certified reference material, pkg of 25 g. Group: Certified reference materials (crms). | |
| VOCs - Loamy Sand 4 | pkg of 30 g. Group: Certified reference materials (crms). | |
| VOCs - Loamy Sand 5 | certified reference material, pkg of 25 g. Group: Certified reference materials (crms). | |
| VOCs - Sandy Loam 1 | pkg of 25 g. Group: Certified reference materials (crms). | |
| VOCs - Sediment 2 | certified reference material, pkg of 25 g. Group: Certified reference materials (crms). | |
| Vofopitant | Vofopitant is potent tachykinin NK 1 receptor antagonist, with pK i s of 10.6, 9.5, and 9.8 for human, rat and ferret NK 1 receptor, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 205171. CAS No. 168266-90-8. Pack Sizes: 5 mg. Product ID: HY-12142. | |
| Vofopitant dihydrochloride | Vofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist, inhibits [ 3 H]SP binding to the NK1 receptor with pK i values of 9.5 and 10.6 in rat and human membranes respectively, acts as a potential broad-spectrum anti-emetic agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GR 205171A. CAS No. 168266-51-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12143. | |
| Vofopitant Dihydrochloride | The dihydrochloride salt form of Vofopitant, a tetrazole compound, has been found to be a neurokinin 1 antagonist that was once studied inbBipolar disorders as well as nausea and vomiting. Synonyms: Vofopitant dihydrochloride; 3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluoro-methyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-, dihydrochloride, (2S,3S)-;3-Piperidinamine, N-[[2-methoxy-5-[5-(trifluoromethyl)-1H-tetrazol-1-yl]phenyl]methyl]-2-phenyl-, dihy. Grades: 98%. CAS No. 168266-51-1. Molecular formula: C21H23F3N6O2HCl. Mole weight: 505.37. | |
| Voglibose | Voglibose is an orally active alpha-glucosidase inhibitor that prevents the development of colorectal precancerous lesions induced by obesity and diabetes. Voglibose reduces oxidative stress in an inflammatory environment and inhibits the insulin-like growth factor/insulin-like growth factor-1 receptor (IGF/IGF-1R) functional axis [1]. Uses: Scientific research. Group: Natural products. CAS No. 83480-29-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-B0025. | |
| Voglibose | Voglibose is an N-substituted derivative of valiolamine, excellent inhibitory activity against α-glucosidases and its action against hyperglycemia and various disorders caused by hyperglycemia. Uses: Hypoglycemic agents. Synonyms: 3,4-Dideoxy-[2-hydroxy-1-(hydroxyethyl)ethyl] amino-1-C-(hydroxynethyl)-1,2,3,4-cyclohexaneterol; 3,4-Dideoxy-4-[[2-hydroxy-1-(hydroxymethyl)ethyl]amino]-2-C-(hydroxymethyl)-D-epiinositol. Grades: >98%. CAS No. 83480-29-9. Molecular formula: C10H21NO7. Mole weight: 267.28. | |
| Voglibose | Voglibose. Group: Biochemicals. Grades: Purified. CAS No. 83480-29-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Voglibose (3, 4-Dideoxy-4-[[2-hydroxy-1- (hydroxymethyl) ethyl]amino]-2-C- (hydroxymethyl) -D-epiinositol) | An alpha-Glucosidase inhibitor used as an antidiabetic. Group: Biochemicals. Alternative Names: 3, 4-Dideoxy-4-[[2-hydroxy-1- (hydroxymethyl) ethyl]amino]-2-C- (hydroxymethyl) -D-epiinositol. Grades: Highly Purified. CAS No. 83480-29-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Volagidemab | Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb). Volagidemab can be used in the research of type 1 diabetes (T1D) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REMD-477; AMG-477. CAS No. 1233956-13-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99383. | |
| Volasertib | Volasertib (BI 6727) is an orally active, highly potent and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with an IC 50 of 0.87 nM. Volasertib inhibits PLK2 and PLK3 with IC 50 s of 5 and 56 nM, respectively. Volasertib induces mitotic arrest and apoptosis. Volasertib, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 6727. CAS No. 755038-65-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12137. | |
| Volasertib | BI 6727 (Volasertib) is a small highly potent Polo-like kinase inhibitor (Plk) with an IC50 of 0.87 nM and EC50 of 11-37 nM on a panel of cancer cell lines, which exhibited significant anti-proliferative in multiple cancer models, including a model of taxane-resistant colorectal cancer. BI 6727 (Volasertib) caused programmed cell death in colon and non-small cell lung cancer cells both in vitro and in vivo. Synonyms: Volasertib; BI-6727; BI6727; BI 6727. Grades: 0.98. CAS No. 755038-65-4. Molecular formula: C34H50N8O3. Mole weight: 618.827. | |
| Volatile acid mixture | Volatile acid mixture. Group: Others. Appearance: Liquid. Storage: 4-8°C. Volatile acid mixture; GC; Volatile Acid Mixture (qualitative); lipid mixture; mix; qualitive mixture; quantitive mixture; Matreya, LLC; Matyera; Larodan; lipid products. Cat No: LMIZ-128. | |
| Volatile Organic Compounds 1 - WP | Proficiency Testing Material, Concentrate for dilution to 100 mL. Group: Waste water. | |
| Volatile Residue/Fixed Solids - WP | Proficiency Testing Material. Group: Waste water. | |
| Volatile Residue - WP | Proficiency Testing Material, Concentrate for dilution to 1L. Group: Waste water. | |
| Volatiles on Sorbent | Proficiency Testing Material. Group: Atomic absorption spectroscopy (aas). | |
| Volinanserin | Volinanserin is a potent and selective antagonist of 5-HT 2 receptor , with a K i of 0.36 nM, and shows 300-fold selectivity for 5-HT 2 receptor over 5-HT 1c , alpha-1 and DA D 2 receptors. Volinanserin has antipsychotic activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDL100907; M 100907. CAS No. 139290-65-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14940. | |
| Volinanserin-d4 Hydrochloride Salt | A labeled serotonin 5-HT2A receptor antagonist. Used as potential controls in various biological studies. Group: Biochemicals. Alternative Names: (αR)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl-d4]-4-piperidinemethanol Hydrochloride; (+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl-d4]-4-piperidinemethanol Hydrochloride; (+)-MDL 100907-d4; M 100907-d4; MDL 100907-d4; R-MDL 100907-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Volinanserin Hydrochloride Salt | A serotonin 5-HT2A receptor antagonist. Used as potential controls in various biological studies. Group: Biochemicals. Alternative Names: (αR)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride; (+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride; (+)-MDL 100907; M 100907; MDL 100907; R-MDL 100907. Grades: Highly Purified. CAS No. 139290-65-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Volixibat | Volixibat (SHP626) is a highly selective, minimally absorbed, and competitive apical sodium-dependent bile acid transporter (ASBT) inhibitor. Volixibat has potential for treatment for non-alcoholic steatohepatitis (NASH) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHP626; LUM002. CAS No. 1025216-57-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101190. | |
| Volkensin | Volkensin is an insect antifeedant isolated from the leaves of the East African tree Melia volkensii. Grades: >98%. CAS No. 91933-11-8. | |
| Volociximab | Volociximab (M200) is a chimeric human/murine IgG4 antibody IIA1 targeting integrin α5β1 ( EC 50 =0.2 nM). Integrin α5β1 is a major fibronectin receptor involved in angiogenesis. Volociximab has antiangiogenic and antitumor activities and inhibits the proliferation of human umbilical vein vascular endothelial cells (HUVECs) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: M200; Eos 200-4. CAS No. 558480-40-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99333. | |
| Vomicine | Vomicine. Group: Biochemicals. Alternative Names: Strychnicine; Struxine. Grades: Plant Grade. CAS No. 125-15-5. Pack Sizes: 10mg. Molecular Formula: C22H24N2O4, Molecular Weight: 380.437. US Biological Life Sciences. | Worldwide |
| vomifoliol dehydrogenase | Oxidizes vomifoliol to dehydrovomifoliol; involved in the metabolism of abscisic acid in Corynebacterium sp. Group: Enzymes. Synonyms: vomifoliol 4'-dehydrogenase; vomifoliol:NAD+ 4'-oxidoreductase. Enzyme Commission Number: EC 1.1.1.221. CAS No. 94949-18-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0127; vomifoliol dehydrogenase; EC 1.1.1.221; 94949-18-5; vomifoliol 4'-dehydrogenase; vomifoliol:NAD+ 4'-oxidoreductase. Cat No: EXWM-0127. | |
| vomilenine glucosyltransferase | The indole alkaloid raucaffricine accumulates during the culture of Rauvolfia cell suspensions. Group: Enzymes. Synonyms: UDPG:vomilenine 21-β-D-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.219. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2447; vomilenine glucosyltransferase; EC 2.4.1.219; UDPG:vomilenine 21-β-D-glucosyltransferase. Cat No: EXWM-2447. | |
| vomilenine reductase | Forms part of the ajmaline biosynthesis pathway. Group: Enzymes. Enzyme Commission Number: EC 1.5.1.32. CAS No. 462127-03-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1514; vomilenine reductase; EC 1.5.1.32; 462127-03-3. Cat No: EXWM-1514. | |
| Vonafexor | Vonafexor (EYP001) is an orally active, non-steroidal and selective FXR agonist. Vonafexor shows significant HBsAg reduction when combined with Peg-IFN&alpha. Vonafexor can be used for anti- HBV research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EYP001. CAS No. 1192171-69-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109197. | |
| vonicog α | Vonicog α is the first and only recombinant von Willebrand Factor(vWF) that offers von Willebrand Factoes(vWF) based on patients needs. It was approved by FDA in Dec. 2015 for the treatment of von Willebrand disease (VWD) in adullt patients. Uses: The treatment of von willebrand disease (vwd). Synonyms: Vonvendi. | |
| Vonoprazan | Vonoprazan is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+ ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. It is used to treat acid-related diseases. It can be used for the treatment of gastroduodenal ulcer (including some drug-induced peptic ulcers) and reflux esophagitis, and can be combined with antibiotics for the eradication of Helicobacter pylori. It is a pyrrole derivative with a chemical structure that is completely different from the P-CABs developed to date in vitro. It inhibits basal gastric acid secretion in a dose-dependent manner, and the ID50 value is 1.26 mg/kg in vivo. It shows a potent and longer-lasting inhibitory effect on the histamine-stimulated gastric acid secretion in rats and dogs. It shows significant antisecretory activity through high accumulation and slow clearance from the gastric tissue. It is unaffected by the gastric secretory state. It was developed by Takeda and Otsuda together. It has been listed. Uses: Vonoprazan is used to treat acid-related diseases. it can be used for the treatment of gastroduodenal ulcer (including some drug-induced peptic ulcers) and reflux esophagitis, and can be combined with antibiotics for the eradication of helicobacter pylori. Synonyms: TAK-438 free base;TAK438 free base; TAK 438 free base; Takecab;1-[5-(2-Fluorophenyl)-1-[(pyridin-3-yl)sulfonyl]-1H-pyrrol-3-yl]-N-methylmethanamine;1H-Pyrrole-3-methanamine,5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl). Grades: >98 %. CAS No. 881681-00-1. Molecular formula: C17H16FN3O2S. Mole weight: 345.39. | |
| Vonoprazan | Vonoprazan (TAK-438 free base), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB) , with antisecretory activity. Vonoprazan inhibits H + ,K + -ATPase activity in porcine gastric microsomes with an IC 50 of 19 nM at pH 6.5. Vonoprazan is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan can be used for eradication of Helicobacter pylori [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-438 free base. CAS No. 881681-00-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-100007. | |
| Vonoprazan Fumarate | TAK-438 is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. Synonyms: TAK438; TAK-438; TAK 438. Grades: 98%. CAS No. 881681-01-2. Molecular formula: C17H16FN3O2S.C4H4O4. Mole weight: 461.46. | |
| Vonoprazan Fumarate | Vonoprazan Fumarate (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB) , with antisecretory activity. Vonoprazan Fumarate inhibits H + ,K + -ATPase activity in porcine gastric microsomes with an IC 50 of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-438. CAS No. 881681-01-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-15295. | |
| Vonoprazan Fumarate Impurity 4 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Grades: 95%. CAS No. 2169271-28-5. Molecular formula: C16H13FN2O3S. Mole weight: 332.35. | |
| Vonoprazan Impuirty 8 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C21H20FN3O6S. Mole weight: 461.47. | |
| Vonoprazan Impurity 1 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: N-methyl(5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine fumarate salt. CAS No. 881732-90-7. Molecular formula: C17H17N3O2S. Mole weight: 327.41. | |
| Vonoprazan Impurity 10 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C34H30N6O4S2. Mole weight: '688.78. | |
| Vonoprazan Impurity 11 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1-(5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-((5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylmethanamine. CAS No. 2250243-23-1. Molecular formula: C33H27F2N5O4S2. Mole weight: 659.74. | |
| Vonoprazan Impurity 12 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C11H7ClFNO. Mole weight: 223.64. | |
| Vonoprazan Impurity 13 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C16H10ClFN2O3S. Mole weight: 364.79. | |
| Vonoprazan Impurity 14 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)-; 5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde; 5-(2-Fluorophenyl)-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-carboxaldehyde. Grades: ≥95%. CAS No. 881677-11-8. Molecular formula: C16H11FN2O3S. Mole weight: 330.34. | |
| Vonoprazan Impurity 15 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C17H16FN3O3S. Mole weight: '361.40. | |
| Vonoprazan Impurity 17 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1883595-38-7; 5-(2-Fluorophenyl)-1H-pyrrole-3-carboxylic acid1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-Vonoprazan Impurity 17CS-0163877. Grades: 95%. CAS No. 1883595-38-7. Molecular formula: C11H8FNO2. Mole weight: 205.18. | |
| Vonoprazan Impurity 19 | One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Grades: 95%. CAS No. 881674-58-4. Molecular formula: C11H10FNO. Mole weight: 191.20. | |
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