A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
An alpha-Glucosidase inhibitor used as an antidiabetic. Group: Biochemicals. Alternative Names: 3, 4-Dideoxy-4-[[2-hydroxy-1- (hydroxymethyl) ethyl]amino]-2-C- (hydroxymethyl) -D-epiinositol. Grades: Highly Purified. CAS No. 83480-29-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Volagidemab
Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb). Volagidemab can be used in the research of type 1 diabetes (T1D) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: REMD-477; AMG-477. CAS No. 1233956-13-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99383.
Volanesorsen
Volanesorsen (ISIS 304801) is an antisense oligonucleotide inhibitor of apolipoprotein CIII (apo-CIII) mRNA that reduces triglyceride levels and improves insulin resistance. Volanesorsen is being studied in the treatment of hypertriglyceridemia, familial chylosiderosis syndrome, and type 2 diabetes[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ISIS 304801. CAS No. 915430-78-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145727.
Volanesorsen sodium
Volanesorsen (ISIS 304801) sodium is an antisense oligonucleotide inhibitor of apolipoprotein CIII (apo-CIII) mRNA that reduces triglyceride levels and improves insulin resistance. Volanesorsen sodium is being studied in the treatment of hypertriglyceridemia, familial chylosiderosis syndrome, and type 2 diabetes[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ISIS 304801 sodium. CAS No. 1573402-50-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145727A.
Volasertib
Volasertib (BI 6727) is an orally active, highly potent and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with an IC 50 of 0.87 nM. Volasertib inhibits PLK2 and PLK3 with IC 50 s of 5 and 56 nM, respectively. Volasertib induces mitotic arrest and apoptosis. Volasertib, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BI 6727. CAS No. 755038-65-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12137.
Volasertib
BI 6727 (Volasertib) is a small highly potent Polo-like kinase inhibitor (Plk) with an IC50 of 0.87 nM and EC50 of 11-37 nM on a panel of cancer cell lines, which exhibited significant anti-proliferative in multiple cancer models, including a model of taxane-resistant colorectal cancer. BI 6727 (Volasertib) caused programmed cell death in colon and non-small cell lung cancer cells both in vitro and in vivo. Synonyms: Volasertib; BI-6727; BI6727; BI 6727. Grades: 0.98. CAS No. 755038-65-4. Molecular formula: C34H50N8O3. Mole weight: 618.827.
Volinanserin is a potent and selective antagonist of 5-HT 2 receptor , with a K i of 0.36 nM, and shows 300-fold selectivity for 5-HT 2 receptor over 5-HT 1c , alpha-1 and DA D 2 receptors. Volinanserin has antipsychotic activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MDL100907; M 100907. CAS No. 139290-65-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14940.
Volinanserin-d4 Hydrochloride Salt
A labeled serotonin 5-HT2A receptor antagonist. Used as potential controls in various biological studies. Group: Biochemicals. Alternative Names: (αR)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl-d4]-4-piperidinemethanol Hydrochloride; (+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl-d4]-4-piperidinemethanol Hydrochloride; (+)-MDL 100907-d4; M 100907-d4; MDL 100907-d4; R-MDL 100907-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Volinanserin Hydrochloride Salt
A serotonin 5-HT2A receptor antagonist. Used as potential controls in various biological studies. Group: Biochemicals. Alternative Names: (αR)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride; (+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol Hydrochloride; (+)-MDL 100907; M 100907; MDL 100907; R-MDL 100907. Grades: Highly Purified. CAS No. 139290-65-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Volixibat
Volixibat (SHP626) is a highly selective, minimally absorbed, and competitive apical sodium-dependent bile acid transporter (ASBT) inhibitor. Volixibat has potential for treatment for non-alcoholic steatohepatitis (NASH) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SHP626; LUM002. CAS No. 1025216-57-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101190.
Volkensin
Volkensin is an insect antifeedant isolated from the leaves of the East African tree Melia volkensii. Grades: >98%. CAS No. 91933-11-8.
Volociximab
Volociximab (M200) is a chimeric human/murine IgG4 antibody IIA1 targeting integrin α5β1 ( EC 50 =0.2 nM). Integrin α5β1 is a major fibronectin receptor involved in angiogenesis. Volociximab has antiangiogenic and antitumor activities and inhibits the proliferation of human umbilical vein vascular endothelial cells (HUVECs) [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: M200; Eos 200-4. CAS No. 558480-40-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99333.
Vomicine
Vomicine. Group: Biochemicals. Alternative Names: Strychnicine; Struxine. Grades: Plant Grade. CAS No. 125-15-5. Pack Sizes: 10mg. Molecular Formula: C22H24N2O4, Molecular Weight: 380.437. US Biological Life Sciences.
Worldwide
vomifoliol dehydrogenase
Oxidizes vomifoliol to dehydrovomifoliol; involved in the metabolism of abscisic acid in Corynebacterium sp. Group: Enzymes. Synonyms: vomifoliol 4'-dehydrogenase; vomifoliol:NAD+ 4'-oxidoreductase. Enzyme Commission Number: EC 1.1.1.221. CAS No. 94949-18-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0127; vomifoliol dehydrogenase; EC 1.1.1.221; 94949-18-5; vomifoliol 4'-dehydrogenase; vomifoliol:NAD+ 4'-oxidoreductase. Cat No: EXWM-0127.
vomilenine glucosyltransferase
The indole alkaloid raucaffricine accumulates during the culture of Rauvolfia cell suspensions. Group: Enzymes. Synonyms: UDPG:vomilenine 21-β-D-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.219. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2447; vomilenine glucosyltransferase; EC 2.4.1.219; UDPG:vomilenine 21-β-D-glucosyltransferase. Cat No: EXWM-2447.
vomilenine reductase
Forms part of the ajmaline biosynthesis pathway. Group: Enzymes. Enzyme Commission Number: EC 1.5.1.32. CAS No. 462127-03-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1514; vomilenine reductase; EC 1.5.1.32; 462127-03-3. Cat No: EXWM-1514.
Vonafexor
Vonafexor (EYP001) is an orally active, non-steroidal and selective FXR agonist. Vonafexor shows significant HBsAg reduction when combined with Peg-IFN&alpha. Vonafexor can be used for anti- HBV research [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EYP001. CAS No. 1192171-69-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109197.
vonicog α
Vonicog α is the first and only recombinant von Willebrand Factor(vWF) that offers von Willebrand Factoes(vWF) based on patients needs. It was approved by FDA in Dec. 2015 for the treatment of von Willebrand disease (VWD) in adullt patients. Uses: The treatment of von willebrand disease (vwd). Synonyms: Vonvendi.
Vonoprazan
Vonoprazan (TAK-438 free base), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB) , with antisecretory activity. Vonoprazan inhibits H + ,K + -ATPase activity in porcine gastric microsomes with an IC 50 of 19 nM at pH 6.5. Vonoprazan is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan can be used for eradication of Helicobacter pylori [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-438 free base. CAS No. 881681-00-1. Pack Sizes: 10 mM * 1 mL; 100 mg; 250 mg. Product ID: HY-100007.
Vonoprazan
Vonoprazan is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+ ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. It is used to treat acid-related diseases. It can be used for the treatment of gastroduodenal ulcer (including some drug-induced peptic ulcers) and reflux esophagitis, and can be combined with antibiotics for the eradication of Helicobacter pylori. It is a pyrrole derivative with a chemical structure that is completely different from the P-CABs developed to date in vitro. It inhibits basal gastric acid secretion in a dose-dependent manner, and the ID50 value is 1.26 mg/kg in vivo. It shows a potent and longer-lasting inhibitory effect on the histamine-stimulated gastric acid secretion in rats and dogs. It shows significant antisecretory activity through high accumulation and slow clearance from the gastric tissue. It is unaffected by the gastric secretory state. It was developed by Takeda and Otsuda together. It has been listed. Uses: Vonoprazan is used to treat acid-related diseases. it can be used for the treatment of gastroduodenal ulcer (including some drug-induced peptic ulcers) and reflux esophagitis, and can be combined with antibiotics for the eradication of helicobacter pylori. Synonyms: TAK-438 free base;TAK438 free base; TAK 438 free base; Takecab;1-[5-(2-Fluorophenyl)-1-[(pyridin-3-yl)sulfonyl]-1H-pyrrol-3-yl]-N-methylmethanamine;1H-Pyrrole-3-methanamine,5-(2-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl). Grades: >98 %. CAS No. 881681-00-1. Molecular formula: C17H16FN3O2S. Mole weight: 345.39.
Vonoprazan Fumarate
Vonoprazan Fumarate (TAK-438), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB) , with antisecretory activity. Vonoprazan Fumarate inhibits H + ,K + -ATPase activity in porcine gastric microsomes with an IC 50 of 19 nM at pH 6.5. Vonoprazan Fumarate is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TAK-438. CAS No. 881681-01-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-15295.
Vonoprazan Fumarate
TAK-438 is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion. Synonyms: TAK438; TAK-438; TAK 438. Grades: 98%. CAS No. 881681-01-2. Molecular formula: C17H16FN3O2S.C4H4O4. Mole weight: 461.46.
Vonoprazan Fumarate Impurity 4
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Grades: 95%. CAS No. 2169271-28-5. Molecular formula: C16H13FN2O3S. Mole weight: 332.35.
Vonoprazan Impuirty 8
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C21H20FN3O6S. Mole weight: 461.47.
Vonoprazan Impurity 1
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: N-methyl(5-phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methanamine fumarate salt. CAS No. 881732-90-7. Molecular formula: C17H17N3O2S. Mole weight: 327.41.
Vonoprazan Impurity 10
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C34H30N6O4S2. Mole weight: '688.78.
Vonoprazan Impurity 11
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1-(5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-((5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylmethanamine. CAS No. 2250243-23-1. Molecular formula: C33H27F2N5O4S2. Mole weight: 659.74.
Vonoprazan Impurity 12
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C11H7ClFNO. Mole weight: 223.64.
Vonoprazan Impurity 13
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C16H10ClFN2O3S. Mole weight: 364.79.
Vonoprazan Impurity 14
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1H-Pyrrole-3-carboxaldehyde, 5-(2-fluorophenyl)-1-(3-pyridinylsulfonyl)-; 5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde; 5-(2-Fluorophenyl)-1-(3-pyridinylsulfonyl)-1H-pyrrole-3-carboxaldehyde. Grades: ≥95%. CAS No. 881677-11-8. Molecular formula: C16H11FN2O3S. Mole weight: 330.34.
Vonoprazan Impurity 15
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C17H16FN3O3S. Mole weight: '361.40.
Vonoprazan Impurity 17
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1883595-38-7; 5-(2-Fluorophenyl)-1H-pyrrole-3-carboxylic acid1H-Pyrrole-3-carboxylic acid, 5-(2-fluorophenyl)-Vonoprazan Impurity 17CS-0163877. Grades: 95%. CAS No. 1883595-38-7. Molecular formula: C11H8FNO2. Mole weight: 205.18.
Vonoprazan Impurity 19
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Grades: 95%. CAS No. 881674-58-4. Molecular formula: C11H10FNO. Mole weight: 191.20.
Vonoprazan Impurity 2
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1-(5-(4-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine; 1H-Pyrrole-3-methanamine, 5-(4-fluorophenyl)-N-methyl-1-(3-pyridinylsulfonyl)-; SCHEMBL1580664; CHEMBL2079304; 1-[5-(4-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamine. CAS No. 881733-36-4. Molecular formula: C17H16FN3O2S. Mole weight: 345.4.
Vonoprazan Impurity 23
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 1-(5-(2-Fluorophenyl)-1H-pyrrol-3-yl)-N-methylmethanamine. Grades: 95%. CAS No. 1610043-62-3. Molecular formula: C12H13FN2. Mole weight: 204.24.
Vonoprazan Impurity 24
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: Vonoprazan N-Oxide Impurity. Grades: 95%. CAS No. 1883595-39-8. Molecular formula: C17H14FN3O3S. Mole weight: 359.37.
Vonoprazan Impurity 27
Vonoprazan Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 122453-85-4. Molecular formula: C11H8N2. Mole weight: 168.2. Catalog: APB122453854.
Vonoprazan Impurity 28
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 2-phenyl-4-formylpyrrole; 5-Phenylpyrrole-3-carbaldehyde. Grades: 95 %. CAS No. 56448-22-7. Molecular formula: C11H9NO. Mole weight: 171.19.
Vonoprazan Impurity 29
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: 881676-90-0; 5-Phenyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde5-phenyl-1-pyridin-3-ylsulfonylpyrrole-3-carbaldehyde; Vonoprazan Impurity 29; SCHEMBL1156702. Grades: 95%. CAS No. 881676-90-0. Molecular formula: C16H12N2O3S. Mole weight: 312.34.
Vonoprazan Impurity 3
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. CAS No. 928325-41-1. Molecular formula: C17H15F2N3O2S. Mole weight: 363.39.
Vonoprazan Impurity 34
Vonoprazan Impurity 34. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1240948-72-4. Molecular formula: C11H6ClFN2. Mole weight: 220.63. Catalog: APB1240948724.
Vonoprazan Impurity 36
Vonoprazan Impurity 36. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1060802-18-7. Molecular formula: C5H3Cl2NO2S. Mole weight: 212.04. Catalog: APB1060802187.
Vonoprazan Impurity 4
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C16H13ClFN3O2S. C4H4O4. Mole weight: 481.89.
Vonoprazan Impurity 5
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C17H18FN3O2S. Mole weight: 347.41.
Vonoprazan Impurity 51
Vonoprazan Impurity 51. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1240949-51-2. Molecular formula: C11H7FN2. Mole weight: 186.19. Catalog: APB1240949512.
Vonoprazan Impurity 6
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C17H20FN3O3S. Mole weight: 365.43.
Vonoprazan Impurity 64
Vonoprazan Impurity 64. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1240948-77-9. Molecular formula: C11H7FN2. Mole weight: 186.19. Catalog: APB1240948779.
Vonoprazan Impurity 67
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Synonyms: N,N-Dimethylmethanamine Vonoprazan. Grades: 95%. CAS No. 1885094-62-1. Molecular formula: C18H18FN3O2S. Mole weight: 359.42.
Vonoprazan Impurity 7
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C17H20FN3O2S. Mole weight: 349.43.
Vonoprazan Impurity 9
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C17H16N3O3S. Mole weight: 361.4.
Vonoprazan Impurity F
One of the impurities of Vonoprazan, which is a potassium-competitive acid blocker and has been found to be effective in the treatment of gastroduodenal ulcer and reflux esophagitis. Molecular formula: C18H18FN3O2S. Mole weight: 359.43.
VO-OHpic
VO-OHpic is a potent inhibitor of PTEN (phosphatase and tensin homolog) (IC50 = 35 nM), displaying selectivity for PTEN over cysteine-based phosphatases including SopB, MTM, PTPβ and SAC (IC50 = 588 nM, 4.03, 57.5 and >10 μM respectively). VO-OHpic has been shown to increase PIP2 and PIP3 levels, and Akt translocation in NIH/3T3 fibroblasts. Synonyms: (OC-6-45)-Aqua(3-hydroxy-2-pyridinecarboxylato-κ-N1,κO2)[3-(hydroxy-κO)-2-pyridinecarboxylato(2-)-κO2]oxovanadate(1-),hydrogen; 3-hydroxypyridine-2-carboxylic acid; oxido(oxo)vanadium. Grades: ≥98% by HPLC. CAS No. 675848-25-6. Molecular formula: C12H10N2O8V. Mole weight: 361.16.
VO-OHpic
VO-OHpic. Group: Biochemicals. Grades: Purified. CAS No. 675848-25-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
VO-Ohpic trihydrate
VO-Ohpic is a highly selective small-molecule inhibitor of phosphatase and tensin homologue deleted on chromosome 10 (PTEN). It is a specific vanadium-based inhibitor screened out from a range of synthesized vanadates and bpV complexes. Synonyms: VO-OHpic; VO OHpic; VOOHpic; VO-Ohpic trihydrate. Grades: >98%. CAS No. 476310-60-8. Molecular formula: C12H15N2O11V. Mole weight: 415.2.
VO-Ohpic trihydrate
VO-Ohpic trihydrate is a highly potent inhibitor of PTEN with an IC 50 of 46±10 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 476310-60-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13074.
A vanadium complex that acts as a highly potent and specific inhibitor of Phosphatase and Tensin Homologue Deleted on Chromosome 10 (PTEN). Group: Biochemicals. Alternative Names: VO(Hhpic-O,O) (Hhpic-O,N)(H2O)]. 3H2O. Grades: Highly Purified. CAS No. 476310-60-8. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
VOPc
VOPc. Uses: Designed for use in research and industrial production. Additional or Alternative Names: VANADYL(IV)-PHTHALOCYANINE;VANADYL PHTHALOCYANINE;VANADIUM(IV) OXIDE PHTHALOCYANINE;VOPC;31h-phthalocyaninato(2-)-n29,n39,n31,n32]-oxo[29(sp-5-12)-vanadiu;PHTHALOCYANINE, VANADYL;OXO(PHTHALOCYANINATO)VANADIUM(IV);Oxyvanadium phthalocyanine. Product Category: Photonic and Optical Device. CAS No. 13930-88-6. Molecular formula: C32H16N8OV. Mole weight: 579.47. Product ID: ACM13930886. Alfa Chemistry ISO 9001:2015 Certified. Categories: Volcano.
Vopimetostat
TNG-462 is an orally active and selective PRMT5 inhibitor with anti-tumor activity against methylthioadenosine phosphorylase (MTAP) deficiency and/or methylthioadenosine (MTA) accumulation cancers[1][2].. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TNG-462. CAS No. 2760483-96-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156680.
Vopratelimab
Vopratelimab (JTX-2011) is a humanized immunoglobulin G1-kappa agonist monoclonal antibody that pecifically binds to the Inducible CO-Stimulator of T cells (ICOS). Vopratelimab retains species cross-reactivity with affinities of 0.93 nM to hICOS, 0.46 nM to cynomolgus ICOS, 3.7 nM to rat ICOS, and 0.64 nM to mICOS. Vopratelimab has antitumor immune response [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: JTX 2011. CAS No. 2039148-04-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99382.
Vorapaxar
Vorapaxar (SCH 530348), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist ( K i =8.1 nM). Vorapaxar (SCH 530348) inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 530348. CAS No. 618385-01-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10119.
Vorapaxar
SCH-530348 is a novel antiplatelet agent undergoing development by Schering-Plough Corp for the treatment and prevention of atherothrombosis. It is currently undergoing Phase-III clinical trials for acute coronary syndrome (unstable angina/non-ST segment elevation myocardial infarction) and secondary prevention of cardiovascular events in high-risk patients. Uses: Platelet aggregation inhibitors. Synonyms: N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-Fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]carbamic Acid Ethyl Ester Sulfate; Sch 530348. Grades: 0.98. CAS No. 618385-01-6. Molecular formula: C29H33FN2O4. Mole weight: 492.58.
Vorapaxar sulfate
Vorapaxar sulfate (SCH 530348 sulfate), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist ( K i =8.1 nM). Vorapaxar sulfate inhibits thrombin receptor-activating peptide (TRAP)-induced platelet aggregation in a dose-dependent manner [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 530348 sulfate. CAS No. 705260-08-8. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10119A.
Vorapaxar, also known as SCH 530348, is a thrombin receptor (protease-activated receptor, PAR-1) antagonist based on the natural product himbacine. Synonyms: SCH530348; SCH 530348, SCH-530348; Vorapaxar sulfate. Grades: 98%. CAS No. 705260-08-8. Molecular formula: C29H35FN2O8S. Mole weight: 590.66.