American Chemical Suppliers

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Product
WAY 170523 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
WAY 170523 WAY 170523. Group: Biochemicals. Grades: Purified. CAS No. 307002-73-9. Pack Sizes: 1mg, 10mg. US Biological Life Sciences. USBiological 5
Worldwide
WAY 170523 WAY 170523 is a potent and selective inhibitor of MMP-13 (IC50 = 17, 945, > 1000 and > 10000 nM for MMP-13, MMP-9, TACE and MMP-1 respectively). Synonyms: WAY-170523; WAY 170523; WAY170523; N-[2-[4-[[[2-[ (Hydroxyamino) carbonyl]-4, 6-dimethylphenyl] (phenylmethyl) amino]sulfonyl]phenoxy]ethyl]-2-benzofurancarboxamide. Grades: ≥99% by HPLC. CAS No. 307002-73-9. Molecular formula: C33H31N3O7S. Mole weight: 613.68. BOC Sciences 10
WAY181187 WAY181187 is a potent and selective 5-HT6 receptor full agonist. It possesses high affinity binding at the human 5-HT6 receptor and profile as full receptor agonists. It induces robust increases in extracellular GABA levels in the frontal cortex, striatum, hippocampus and amygdala of rats. It has modest to no effects on norepinephrine, serotonin, dopamine, or glutamate levels. It has demonstrated preclinical efficacy in rodent models of depression, anxiety, and notably obsessive-compulsive disorder. Uses: Way181187 has demonstrated preclinical efficacy in rodent models of depression, anxiety, and notably obsessive-compulsive disorder. Synonyms: WAY-181187; WAY 181187; WAY181187;2-(1-((6-Chloroimidazo(2,1-b)(1,3)thiazol-5-yl)sulfonyl)-1H-indol-3-yl)ethylamine;SAX-187;SAX187; SAX 187. Grades: 98%. CAS No. 554403-49-5. Molecular formula: C15H13ClN4O2S2. Mole weight: 380.86. BOC Sciences 10
WAY-181187 WAY-181187 (SAX-187) is a potent and selective full 5-HT6 receptor agonist with a K i of 2.2 nM and an EC 50 of 6.6 nM [1]. WAY181187 mediates 5-HT6 receptor-dependent signal pathways, such as cAMP, Fyn and ERK1/2 kinase, as specific agonist [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SAX-187. CAS No. 554403-49-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-14340. MedChemExpress MCE
WAY 181187 oxalate WAY 181187 oxalate is a selective and high affinity 5-HT6 agonist with 60-fold selectivity over other 5-HT and monoamine receptors. Synonyms: WAY 181187 oxalate; WAY181187 oxalate; WAY-181187 oxalate; 1-[(6-Chloroimidazo[2,1-b]thiazol-5-yl)sulfonyl]-1H-indole-3-ethanamine oxalate. Grades: ≥98% by HPLC. CAS No. 1883548-85-3. Molecular formula: C15H13ClN4O2S2.C2H2O4. Mole weight: 470.91. BOC Sciences 10
WAY 200070 WAY 200070. Group: Biochemicals. Grades: Purified. CAS No. 440122-66-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
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WAY-200070 WAY-200070 is a selective estrogen receptor β ( ERβ ) agonist with an IC 50 of 2.3 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 440122-66-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101271. MedChemExpress MCE
WAY-200070 WAY-200070 is a selective estrogen receptor β (ERRβ) agonist (IC50 = 2.3 nM) that exhibit 68-fold selectivity over ERα (EC50 = 155 nM for ERα). Synonyms: 4-(7-bromo-5-hydroxy-3H-1,3-benzoxazol-2-ylidene)cyclohexa-2,5-dien-1-one; Br-ERb-041; WAY 200070; WAY 20070-3; WAY-200070; WAY-200070-3; WAY200070; WAY200070-3. CAS No. 440122-66-7. Molecular formula: C13H8BrNO3. Mole weight: 306.11. BOC Sciences 10
WAY 207024 dihydrochloride WAY 207024 dihydrochloride is a potent and orally bioactive antagonist of gonadotropin releasing hormone receptor (GnRH-R) (IC50 = 12 and 71 nM for human and rat GnRH receptors, respectively). WAY 207024 dihydrochloride was shown to decrease plasma leuteinizing hormone levels in the rat. Synonyms: WAY-207024 ; WAY 207024 ; WAY207024; WAY 207024 dihydrochloride; WAY 207024 diHCl; 6-[[4-[2-[4-(1,1-Dimethylethyl)phenyl]-1H-benzimidazol-7-yl]-i-piperazinyl]methyl]-quinoxaline dihydrochloride. Grades: ≥99% by HPLC. CAS No. 872002-73-8. Molecular formula: C30H32N6.2HCl. Mole weight: 549.54. BOC Sciences 11
WAY 208466 dihydrochloride WAY 208466 dihydrochloride is a high affinity and selective 5-HT6 agonist (EC50 = 7.3 nM at the human 5-HT6 receptor) with antidepressant and anxiolytic activity. WAY 208466 dihydrochloride was shown to increase cortical GABA levels in vivo in rat frontal cortex. Synonyms: WAY-208466 2HCl; WAY 208466 2HCl; WAY208466 2HCl; WAY-208466 dihydrochloride; WAY 208466 dihydrochloride; WAY208466 dihydrochloride; 3-[(-3-Fluorophenyl)sulfonyl]-N,N-dimethyl-1H-pyrrolo[2,3-b]pyridine-1-ethanamine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 1207064-61-6. Molecular formula: C17H18FN3O2S.2HCl. Mole weight: 420.33. BOC Sciences 10
WAY-208466 dihydrochloride ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
WAY208466 dihydrochloride WAY 208466 dihydrochloride is a potent and selective 5-HT 6 receptor agonist ( EC 50 =7.3 nM for the human 5-HT 6 receptor). WAY-208466 dihydrochloride elevates cortical GABA levels in rat frontal cortex [1]. WAY 208466 dihydrochloride exhibits antidepressant and anxiolytic-like effects [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1207064-61-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103133. MedChemExpress MCE
WAY 213613 WAY 213613 is a potent and non-substrate inhibitor of EAAT2 (GLT-1), displaying > 44-fold selectivity over EAAT1 and EAAT3 (IC50 = 85, 3787 and 5004 nM for EAAT2, EAAT3 and EAAT1, respectively). WAY 213613 exhibits no activity towards ionotropic and metabotropic glutamate receptors. Synonyms: WAY 213613; WAY213613; WAY-213613; N-[4-(2-Bromo-4,5-difluorophenoxy)phenyl]-L-asparagine; (2S)-2-amino-4-[4-(2-bromo-4,5-difluorophenoxy)anilino]-4-oxobutanoic acid. Grades: ≥99% by HPLC. CAS No. 868359-05-1. Molecular formula: C16H13BrF2N2O4. Mole weight: 415.19. BOC Sciences 11
WAY 213613 WAY 213613. Group: Biochemicals. Grades: Purified. CAS No. 868359-05-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
WAY-213613 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
WAY-252623 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
WAY-255348 WAY-255348 is a potent nonsteroidal progesterone receptor (PR) antagonist. WAY-255348 inhibits the activity of progesterone. WAY-255348 achieves antagonist activity by binding to and subsequently preventing progesterone-induced nuclear accumulation, phosphorylation and promoter interactions of the PR. Synonyms: WAY255348; WAY 255348. Grades: 98%. CAS No. 872141-23-6. Molecular formula: C16H14FN3O. Mole weight: 283.30. BOC Sciences 11
WAY-262611 WAY-262611 is a Wnt / β-Catenin agonist that increases bone formation rate with an EC 50 of 0.63 μM in TCF-Luciferase assay. WAY-262611 is also a Dkk1 inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1123231-07-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-11035. MedChemExpress MCE
WAY-262611 WAY-262611 is a wingless beta-Catenin agonist that increases bone formation rate. Synonyms: WAY262611 2HCl; WAY262611 2HCl; WAY-262611 2HCl; WAY 262611 dihydrochloride; WAY-262611 dihydrochloride WAY 262611 dihydrochloride. Grades: >98%. CAS No. 1123231-07-1. Molecular formula: C20H22N4. Mole weight: 318.42. BOC Sciences 10
WAY 262611 dihydrochloride WAY 262611 dihydrochloride is an inhibitor of Dickkopf-1 (DKK1), which antagonizes Wnt/β-Catenin signaling. DKK1 is a soluble inhibitor of Wnt-3a mediated Wnt/β-catenin signaling required for embryonic head development. Inhibition of DKK1 by WAY 262611 activates the Wnt signaling pathway and stimulates β-catenin/TCF-dependent transcription with an EC50 value of 0.63 μM. Synonyms: WAY-262611 dihydrochloride; WAY 262611 dihydrochloride; WAY262611 dihydrochloride; (1-(4-(naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine dihydrochloride. Grades: 99%. Molecular formula: C20H22N4.2HCl. Mole weight: 391.34. BOC Sciences 10
WAY 267464 dihydrochloride WAY 267464 dihydrochloride is a potent and selective non-peptide oxytocin receptor (OTR) agonist (Ki = 58.4 nM at human OTR), displaying anxiolytic-like effects. WAY 267464 may be beneficial for the treatment of psychosis and schizophrenia. Synonyms: WAY 267464 dihydrochloride; WAY267464 dihydrochloride; WAY-267464 dihydrochloride; N-[[4-[(4,10-Dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]-2-methylphenyl]methyl]-4-[(3,5-dihydroxyphenyl)methyl]-1-piperazinecarboxamide dihydrochloride. Grades: ≥97% by HPLC. CAS No. 1432043-31-6. Molecular formula: C32H35N7O4.2HCl. Mole weight: 654.59. BOC Sciences 9
WAY-267464 dihydrochloride ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
WAY-300716 WAY-300716 is a useful chemical reagent for laboratory study. Uses: Designed for use in research and industrial production. Additional or Alternative Names: WAY-300716; WAY 300716; WAY300716. Product Category: Others. Appearance: To be determined. CAS No. 223735-93-1. Molecular formula: C16H14ClNO. Mole weight: 271.74. Purity: >98%. IUPACName: (4-Chlorophenyl)(3,4-dihydro-2(1H)-isoquinolinyl)methanone. Canonical SMILES: O=C(C1=CC=C(Cl)C=C1)N2CC3=C(C=CC=C3)CC2. Product ID: ACM223735931. Alfa Chemistry — ISO 9001:2015 Certified. Categories: 2-(4-chlorobenzoyl)-1,2,3,4-tetrahydroisoquinoline. Alfa Chemistry.
WAY-316606 WAY-316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. Modulators of the Wnt pathway have been proposed as anabolic agents for the treatment of osteoporosis or other bone-related disorders. WAY-316606 bound to sFRP-1 with a Kd of 0.08 mM and inhibited it with an EC50 of 0.65 mM. Synonyms: WAY 316606; 5-(phenylsulfonyl)-N-(piperidin-4-yl)-2-(trifluoromethyl)benzenesulfonamide. Grades: >98%. CAS No. 915759-45-4. Molecular formula: C18H19F3N2O4S2. Mole weight: 448.475. BOC Sciences 9
WAY 316606 hydrochloride WAY 316606 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
WAY 316606 hydrochloride WAY 316606 hydrochloride is a secreted Frizzled-Related Protein-1 (sFRP-1) inhibitor (IC50 = 0.65 μM). WAY 316606 hydrochloride stimulates the Wnt/β-catenin canonical signaling pathway and prevents sFRP-1 from interacting with Wnt signaling. Synonyms: WAY 316606 hydrochloride; WAY316606 hydrochloride; WAY-316606 hydrochloride; 5-(Phenylsulfonyl)-N-4-piperidinyl-2-(trifluoromethyl)benzene sulfonamide hydrochloride. Grades: ≥99% by HPLC. CAS No. 1781835-02-6. Molecular formula: C18H19F3N2O4S2.HCl. Mole weight: 484.94. BOC Sciences 9
WAY-320461 WAY-320461 is a FAK inhibitor. Synonyms: WAY 320461; WAY320461. CAS No. 491839-65-7. Molecular formula: C15H10BrN3O2S. Mole weight: 376.2. BOC Sciences 8
WAY-323096 WAY-323096 is a bioactive compound. Synonyms: WAY 323096; WAY323096; 2-(4-(4-Chlorophenyl)-1-oxophthalazin-2(1H)-yl)-N-(4-fluorophenyl)acetamide. CAS No. 684234-60-4. Molecular formula: C22H15ClFN3O2. Mole weight: 407.8. BOC Sciences 8
WAY-332076 WAY-332076. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1015865-34-5. Molecular formula: C20H18ClFN2O3S. Mole weight: 420.88. Catalog: APB1015865345. Alfa Chemistry Analytical Products 4
WAY-348941 WAY-348941 is an immunosuppressive agent. Uses: Designed for use in research and industrial production. Additional or Alternative Names: WAY-348941; WAY 348941; WAY348941. Product Category: Inhibitors. Appearance: To be determined. CAS No. 113143-13-8. Molecular formula: C14H11N3OS. Mole weight: 269.32. Purity: >98%. IUPACName: 2-Thiophenecarboxylic acid, 2-(1H-indol-3-ylmethylene)hydrazide. Canonical SMILES: O=C(C1=CC=CS1)N/N=C/C2=CNC3=C2C=CC=C3. Product ID: ACM113143138. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
WAY-362450 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
WAY-600 WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: WAY600; WAY 600; WAY600. Product Category: Inhibitors. Appearance: White solid powder. CAS No. 1062159-35-6. Molecular formula: C28H30N8O. Mole weight: 494.59. Purity: >98%. IUPACName: 4-(6-(1H-indol-5-yl)-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)morpholine. Canonical SMILES: N1(C2=C3C(N(C4CCN(CC5=CC=CN=C5)CC4)N=C3)=NC(C6=CC7=C(NC=C7)C=C6)=N2)CCOCC1. Product ID: ACM1062159356. Alfa Chemistry — ISO 9001:2015 Certified. Categories: WAY-100635. Alfa Chemistry.
WAY-600 WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM. Synonyms: WAY 600; WAY600. Grades: 98%. CAS No. 1062159-35-6. Molecular formula: C28H30N8O. Mole weight: 494.603. BOC Sciences 10
WAY-604116 WAY-604116 is a 11-β-hydroxysteroid dehydrogenase inhibitor. Uses: Designed for use in research and industrial production. Additional or Alternative Names: WAY-604116; WAY 604116; WAY604116. Product Category: Inhibitors. Appearance: To be determined. CAS No. 121768-39-6. Molecular formula: C17H22N2O. Mole weight: 270.38. Purity: >98%. IUPACName: (3r,5r,7r)-N-(pyridin-4-ylmethyl)adamantane-1-carboxamide. Canonical SMILES: O=C(NCC1=CC=NC=C1)C2(C[C@@H]3C4)C[C@H](C3)C[C@H]4C2. Product ID: ACM121768396. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Aromatase-IN-2. Alfa Chemistry.
WAY-621089 WAY-621089 is an active molecule for the study of amyloid diseases and synucleinopathies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 303790-92-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-47595. MedChemExpress MCE
WAY 629 hydrochloride WAY 629 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 57756-44-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
WAY 629 hydrochloride WAY 629 hydrochloride is a selective 5-HT2C agonist (Ki = 56, 2350, 1575 and 815 nM for human recombinant 5-HT2C, 5-HT2A, 5-HT6 and 5-HT7 receptors, respectively). WAY 629 promotes intracellular Ca2+ mobilization in CHO cells expressing human 5-HT2C receptors (EC50 = 72 nM). Synonyms: [1,4]Diazepino[6,7,1-jk]carbazole, 4,5,6,7,9,10,11,12-octahydro-, hydrochloride (1:1); WAY629 hydrochloride; WAY-629 hydrochloride; 1,2,3,4,8,9,10,11-Octahydro[1,4]diazepino[6,7,1-jk]carbazole hydrochloride; [1,4]Diazepino[6,7,1-jk]carbazole, 1,2,3,4,8,9,10,11-octahydro-, monohydrochloride. Grades: ≥98% by HPLC. CAS No. 57756-44-2. Molecular formula: C15H18N2.HCl. Mole weight: 262.78. BOC Sciences 10
WAY-638394 WAY-638394 is a laboratory reagent, which may be useful for treating bone deficit conditions. Uses: Designed for use in research and industrial production. Additional or Alternative Names: WAY-638394; WAY 638394; WAY638394. Product Category: Others. Appearance: To be determined. CAS No. 190437-83-3. Molecular formula: C20H19N3O2. Mole weight: 333.39. Purity: >98%. IUPACName: N-[4-(4-Morpholinyl)phenyl]-2-quinolinecarboxamide. Canonical SMILES: O=C(C1=NC2=CC=CC=C2C=C1)NC3=CC=C(N4CCOCC4)C=C3. Product ID: ACM190437833. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
WAY-641966 WAY-641966 is an anti-prion agent. Synonyms: WAY 641966; WAY641966. CAS No. 259870-32-1. Molecular formula: C20H16N4. Mole weight: 312.4. BOC Sciences 8
WAY-647802 WAY-647802 is a CDK inhibitor. Uses: Designed for use in research and industrial production. Additional or Alternative Names: WAY-647802; WAY 647802; WAY647802. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 852225-20-8. Molecular formula: C11H14N4O3. Mole weight: 250.26. Purity: >98%. IUPACName: Ethanone, 1-[4-(6-nitro-3-pyridinyl)-1-piperazinyl]. Canonical SMILES: CC(N1CCN(C2=CC=C([N+]([O-])=O)N=C2)CC1)=O. Product ID: ACM852225208. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
WB-3559A WB-3559A is a fibrinolytic metabolite produced by Flavobacterium sp. Synonyms: WB-3559 A; WB 3559 A. CAS No. 96053-97-3. Molecular formula: C36H66N2O7. Mole weight: 638.9. BOC Sciences 5
WB-3559B WB-3559B is a fibrinolytic metabolite produced by Flavobacterium sp. Synonyms: WB-3559 B; WB 3559 B. CAS No. 96053-96-2. Molecular formula: C37H68N2O7. Mole weight: 652.9. BOC Sciences 5
WB-3559C WB-3559C is a fibrinolytic metabolite produced by Flavobacterium sp. Synonyms: WB-3559 C; WB 3559 C. CAS No. 96095-05-5. Molecular formula: C36H68N2O7. Mole weight: 640.9. BOC Sciences 5
WB-3559D WB-3559D is a fibrinolytic metabolite produced by Flavobacterium sp. Synonyms: WB-3559 D; WB 3559 D. CAS No. 96095-04-4. Molecular formula: C37H70N2O7. Mole weight: 655. BOC Sciences 5
WB 4101 hydrochloride WB 4101 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 2170-58-3. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 5
Worldwide
WB 4101 hydrochloride WB 4101 hydrochloride is a selective α1A-adrenergic receptor antagonist. Synonyms: WB 4101; WB-4101; WB4101; WB 4101 hydrochloride; WB 4101 HCl. 2-(2,6-Dimethoxyphenoxyethyl)aminomethyl-1,4-benzodioxane hydrochloride. Grades: ≥99% by HPLC. CAS No. 2170-58-3. Molecular formula: C19H23NO5.HCl. Mole weight: 381.86. BOC Sciences 10
WBC100 WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc molecule glue degrader. WBC100 is a c-Myc degrader and targets ubiquitin E3 ligase CHIP mediated 26S proteasome pathway. WBC100 is used for c-Myc overexpressing tumors research[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 14-D-Valine-TPL. CAS No. 2095780-08-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145898. MedChemExpress MCE
WC/15Co WC/15Co. Group: Nitrides. 0.999. Alfa Chemistry Materials 3
WCK-4234 sodium WCK-4234 is a potent β-lactamase inhibitor. WCK-4234 inhibited class A, C and D β-lactamases with unprecedented k2/K values against OXA carbapenemases. WCK-4234 inhibited class A, C and D β-lactamases with unprecedented k2/K values against OXA carbapenemases. WCK-4234 formed highly stable acyl-complexes via mass spectrometry. WCK-4234 is a novel β-lactamase inhibitor that demonstate potent cross-class inhibition and clinical studies targeting MDR infections are warranted. Uses: Designed for use in research and industrial production. Additional or Alternative Names: WCK-4234; WCK 4234; WCK4234. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1804915-68-1. Molecular formula: C7H8N3NaO5S. Mole weight: 269.21. Purity: >98%. IUPACName: sodium (2S,5R)-2-cyano-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl sulfate. Canonical SMILES: O=S(ON1[C@]2([H])CC[C@@H](C#N)N(C2)C1=O)([O-])=O.[Na+]. Product ID: ACM1804915681. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
WCK-5153 WCK-5153 is a Novel Inhibitor of PBP2 Showing Potent "β-Lactam Enhancer" Activity against Pseudomonas aeruginosa, Including Multidrug-Resistant Metallo-β-Lactamase-Producing High-Risk Clones. WCK 5153 demonstrated specific high-affinity binding to PBP2 of A. baumannii. WCK 5153 shows a potent β-lactam enhancer effect against A. baumannii, including a multidrug-resistant OXA-23-producing ST2 international clone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: WCK-5153; WCK 5153; WCK5153. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1436862-38-2. Molecular formula: C12H19N5O7S. Mole weight: 377.37. Purity: >98%. IUPACName: (2S,5R)-7-oxo-2-(2-((S)-pyrrolidine-3-carbonyl)hydrazine-1-carbonyl)-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate. Canonical SMILES: O=C(NNC([C@H]1N(C[C@H]2CC1)C(N2OS(=O)(O)=O)=O)=O)[C@H]3CCNC3. Product ID: ACM1436862382. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
w-Conotoxin s vib(9ci) w-Conotoxin s vib(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: OMEGA-CONOTOXIN SVIB;CYS-LYS-LEU-LYS-GLY-GLN-SER-CYS-ARG-LYS-THR-SER-TYR-ASP-CYS-CYS-SER-GLY-SER-CYS-GLY-ARG-SER-GLY-LYS-CYS-NH2;H-CYS-LYS-LEU-LYS-GLY-GLY-SER-CYS-ARG-LYS-THR-SER-TYR-ASP-CYS-CYS-SER-GLY-CYS-GLY-ARG-SER-GLY-LYS-CYS-NH2;ω-CgTx SVIB;ω-Cono. Product Category: Heterocyclic Organic Compound. CAS No. 150433-82-2. Molecular formula: C105H176N38O36S6. Mole weight: 2739.14. Purity: 0.96. IUPACName: chlorane. Canonical SMILES: Cl. ECNumber: 231-595-7. Product ID: ACM150433822. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
WD6305 TFA WD6305 TFA is a potent and selective METTL3-METTL14 PROTAC degrader. WD6305 TFA has DC50 values of 140 nM and 194 nM for METTL3 and METTL14, respectively. WD6305 TFA inhibits m6A modification and proliferation of AML cells, and induces apoptosis. WD6305 TFA has antitumor activity[1].(Pink: UZH2 (HY-115717); Black: Linker; Blue: VHL ligand (HY-150803)). Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160415A. MedChemExpress MCE
WDR5 0103 WDR5 0103. Group: Biochemicals. Grades: Purified. CAS No. 890190-22-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
WDR5-0103 WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 with Kd of 450 nM. It inhibits MLL catalytic activity with an IC50 value of 39±10 μM in vitro. It is a WD40-repeat antagonist that binds to WDR55 central cavity. It inhibits MLL1 histone methyltransferase activity in vitro through disruption of the interaction of MLL with WDR5. It is an essential componet of the human trithorax-like famliy of SET1 methyltransferase complexes that carry out trimethylation of histone 3 Lys4. Uses: Wdr5-0103 inhibits mll1 histone methyltransferase activity. it is an essential componet of the human trithorax-like famliy of set1 methyltransferase complexes that carry out trimethylation of histone 3 lys4. Synonyms: 3-[(3-Methoxybenzoyl)aMino]-4-(4-Methyl-1-piperazinyl)benzoic Acid Methyl Ester;Methyl 3-(3-methoxybenzamido)-4-(4-methylpiperazin-1-yl)benzoate;WDR5-0103; WDR 5-0103; WDR-5-0103; WDR50103; WDR-50103; WDR 50103; WD-Repeat Protein 5-0103. Grades: >98 %. CAS No. 890190-22-4. Molecular formula: C21H25N3O4. Mole weight: 383.44. BOC Sciences 10
WDR5-0103 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
WDR5 human recombinant, expressed in baculovirus infected Sf9 cells, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
WDR5-IN-4 WDR5-IN-4 (Compound C6) is a WIN site inhibitor of chromatin-associated WD repeat domain 5 protein (WDR5), Kd The value is 0.1 nM. WDR5-IN-4 is able to displace WDR5 from chromatin and reduce the expression of related genes, causing translation inhibition and nucleolar stress. Has anti-cancer effects [1][1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2407457-36-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-111753. MedChemExpress MCE
WDR5-IN-5 WDR5-IN-5 is an orally active and selective inhibitor of WIN site of WD repeat domain 5 (WDR5). WDR5-IN-5 exhibits anti-proliferative activity towards cancer cells and good pharmacokinetics profile in mice. WDR5-IN-5 shows high affinity to WDR5 and the binding affinity Ki value <0.02 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2417012-26-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-150654. MedChemExpress MCE
WDR5-IN-6 WDR5-IN-6 is a WDR5 inhibitor, targeting to WBM site. WDR5-IN-6 inhibits cell proliferation of neuroblastoma cell lines with potent anti-tumor activity. WDR5-IN-6 shows high synergy with OICR-9429 (HY-16993), a WDR5 inhibitor targeting to WIN site. WDR5-IN-6 can be used for reasearch in neuroblastoma[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 326901-92-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-154949. MedChemExpress MCE
WDR9 (1308-1436) human recombinant, expressed in E. coli, ?82% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
WD repeat domain 16 (145-175) BOC Sciences 3
WE-14 trifluoroacetate salt ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
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