A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Wool wax, stearin, ester with pentaerythritol. CAS No. 100085-82-3. Catalog: ACM100085823.
Worenine
Botanical Source: Group: Biochemicals. Alternative Names: 5, 6-Dihydro-14-methylbis[1, 3]benzodioxolo[5, 6-a:5?, 6?-g]quinolizinium(1+), 9CI. 13-Methylpseudocoptisine. Grades: Plant Grade. CAS No. 38763-29-0. Pack Sizes: 10mg, 20mg. US Biological Life Sciences.
Worldwide
Wormwood Extract
Wormwood Extract. Applications: Used for health care products, dietary supplements, herb medecine, mainly for antibacterial. Group: Others. Synonyms: Wormwood Extract; 977032-37-3; Artemisia princes orientalis L. CAS No. 977032-37-3. Purity: 4-10:1 by TLC. Appearance: Yellow brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Leaf. Species: Artemisia princes orientalis L. Wormwood Extract; 977032-37-3; Artemisia princes orientalis L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-130.
Wortmannin (SL-2052; KY-12420) is a potent, selective and irreversible PI3K inhibitor with an IC50 of 3 nM. Wortmannin also blocks autophagy formation, and potently inhibits Polo-like kinase 1 (PlK1) and Plk3 with IC50s of 5.8 and 48 nM, respectively. Group: Inhibitors. Alternative Names: Wartmannin. CAS No. 19545-26-7. Molecular formula: C23H24O8. Mole weight: 428.43. Purity: 0.98. Catalog: ACM19545267.
Wortmannin
Wortmannin (SL-2052; KY-12420) is a potent, selective and irreversible PI3K inhibitor with an IC 50 of 3 nM. Wortmannin also blocks autophagy formation, and potently inhibits Polo-like kinase 1 (PlK1) and Plk3 with IC 50 s of 5.8 and 48 nM, respectively [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: SL-2052; KY-12420. CAS No. 19545-26-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10197.
Wortmannin
It is an antibiotic produced by the strain of Pen. wortmanni 989. It has strong antifungal effect. It is a specific covalent inhibitor of phosphoinositide 3-kinases (PI3Ks) and Polo-Like kinase 1 (PLK1). It is a commonly used cell biology reagent that has been used previously in research to inhibit DNA repair, receptor-mediated endocytosis and cell proliferation. Uses: Immunosuppressive agents. Synonyms: Antibiotic SL-2052; (1alpha,11alpha)-11-(Acetyloxy)-1-(methoxymethyl)-2-oxaandrosta-5,8-dieno(6,5,4-bc)furan-3,7,17-trione; (1S,6bR,9aS,11R,11bR)-1-(Methoxymethyl)-9a,11b-dimethyl-3,6,9-trioxo-1,6,6b,7,8,9,9a,10,11,11b-decahydro-3H-furo[4,3,2-de]indeno[4,5-h]isochromen-11-yl acetate. Grades: 98%. CAS No. 19545-26-7. Molecular formula: C23H24O8. Mole weight: 428.43.
Wortmannin
Antibiotic. Potent anti-neutrophil agent with cardioprotective effects. mTOR, DNA-PK, phosphatidylinositol 4-kinases, myosin light chain kinase (MLCK) and mitogen-activated protein kinase (MAPK) inhibitor at high concentrations. Potent cell permeable and selective inhibitor of phosphatidyl-inositol 3-kinase (PI3K). Antitumor compound. Radiosensitizing agent. Adipogenesis inhibitor. Angiogenesis inhibitor. Autophagy inhibitor. DNA repair, receptor-mediated endocytosis and cell proliferation inhibitor. Potentiates the LPS-induced nitric oxide (NO) production from macrophages. Induces in vivo Alzheimer-like hyperphosphorylation in tau. Polo-like kinase family inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 19545-26-7. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C23H24O8. US Biological Life Sciences.
Worldwide
Wortmannin-Rapamycin Conjugate
Wortmannin is a potent inhibitor of PI3K enzymes, and rapamycin blocks mTOR. The wortmannin-rapamycin conjugate inhibits the growth of HT-29 colon tumors and A498 renal tumors in mice better than rapamycin alone. Synonyms: Wortmannin-Rapamycin Conjugate; 1067892-47-0; AKOS040755180. Grades: ≥98%. CAS No. 1067892-47-0. Molecular formula: C88H131N3O23. Mole weight: 1598.9.
WP-1034
WP-1034 is a novel Jak-Stat inhibitor, which is active against AML blasts. WP-1034 effectively inhibited proliferation of OCIM2 cells and fresh AML samples. WP-1034 caused cell cycle arrest of OCIM2 cells in sub-Go phase. WP-1034 induced apoptosis of OCIM2 cells and that induction of apoptosis involved cleavage of caspase 3 and the DNA repair enzyme poly (adenosine diphosphate [ADP]-ribose) polymerase (PARP). Synonyms: WP1034; WP 1034; (R,E)-2-cyano-3-(4-nitrophenyl)-N-(1-phenylethyl)acrylamide. CAS No. 857064-42-7. Molecular formula: C18H15N3O3. Mole weight: 321.33.
WP1066
WP1066 is a JAK2 and STAT3 inhibitor. It was shown to inhibit proliferation and induce apoptosis in erythroid human cells carrying the JAK2 V617F mutation. Synonyms: (E)-3-(6-bromopyridin-2-yl)-2-cyano-N-[(1S)-1-phenylethyl]prop-2-enamide. Grades: >98%. CAS No. 857064-38-1. Molecular formula: C17H14BrN3O. Mole weight: 356.223.
WP1066
WP1066 is an inhibitor of JAK2 and STAT3 , and also shows effect on STAT5 and ERK1/2, without affecting JAK1 and JAK3. Uses: Scientific research. Group: Signaling pathways. CAS No. 857064-38-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15312.
A potent, cell-permeable JAK2 inhibitor. A novel analog of the JAK2 inhibitor AG490 that blocks STAT3 and phosphoinositide-3-kinase pathways. It is significantly more potent and active against human malignant glioma cells in vitro and in vivo than AG 490. Similar to AG490, WP1066 inhibits the phosphorylation of JAK2, but unlike AG490, WP1066 also degrades JAK2 protein, thus blocking its downstream signal transducer and activator of transcription (STAT) and phosphoinositide-3-kinase pathways to results in the activation of the caspase pathway. Group: Biochemicals. Grades: Purified. CAS No. 857064-38-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
WP1130 (Degrasyn)
A cell-permeable tyrphostin compound that acts as a partially selective deubiquitinase (DUB) inhibitor and suppresses JAK-Stat signaling pathway. Reported to cause accumulation of polyubiquitinated p53, JAK2 and Bcr-Abl, and reduce c-Myc and MCL-1 protein levels in several tumor cells and downregulate Stat3 and NF-kB activities (IC50 < 1uM in MCL cells) leading to tumor cell apoptosis (IC50 ~1.2uM in Z138 cells). Suggested to modify active site cysteine of DUB and inhibit USP5, UCH-L1, USP9x, USP14, and UCH37 activities (≥80% inhibition at 5uM) without affecting 20S proteasome. Reported to exert stronger antiproliferative and antitumor properties than STAT3 Inhibitor III, WP1066 in xenograft mouse models of CML and melanoma. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Cell-permeable. WP1130 acts as a partly selective DUB (deubiquitinases) inhibitor, directly inhibiting DUB activity of USP9x, USP5, USP14, and UCH37, which are known to regulate survival protein stability and 26S proteasome function. WP1130-mediated inhibition of tumor-activated DUBs results in downregulation of antiapoptotic and upregulation of proapoptotic proteins, such as MCL-1 and p53. Blocks JAK2 signaling via JAK2 ubiquitination. Group: Biochemicals. Grades: Highly Purified. CAS No. 856243-80-6. Pack Sizes: 5mg, 25mg. US Biological Life Sciences.
Worldwide
WP9QY
WP9QY, TNF-a Antagonist, TNF-a Antagonist is a biological active peptide. (This cyclic peptide is designed to mimic the most critical tumor necrosis factor (TNF) recognition loop on TNF receptor I. It prevents interactions of TNF with its receptor. This TNF antagonist is a useful template for the development of small molecular inhibitors to prevent both inflammatory bone destruction and systemic bone loss in rheumatoid arthritis.). Uses: Scientific research. Group: Peptides. CAS No. 199999-60-5. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P2612.
WQ3810 is a newly developed fluoroquinolone withunique substituents at the N1 and C7 positions of the quinolone ringfor the treatment of antibiotic-resistant infections. Synonyms: 1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-8-methyl-4-oxo-7-[3-(propan-2-ylamino)azetidin-1-yl]quinoline-3-carboxylic acid; 1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-7-(3-(isopropylamino)azetidin-1-yl)-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; WQ-3810; WQ 3810; WQ3810. CAS No. 888032-58-4. Molecular formula: C22H22F3N5O3. Mole weight: 461.44.
WR 1065
WR 1065 is a metabolite of Amifostine, and a cell-permeable reactive oxygen species scavenger that activates p53 through a JNK-dependent signaling pathway. WR 1065 activates p21waf-1 and MDM2 and inhibits DNA topoisomerase II&alpha. WR 1065 can induce cell cycle arrest and exert cytoprotective activity towards normal cells but not cancer cells in vivo. Synonyms: NSC345308; NSC 345308; NSC-345308; WR1065 Dihydrochloride; WR 1065 Dihydrochloride; WR-1065 Dihydrochloride; 2-[(3-Aminopropyl)amino]ethanethiol dihydrochloride; WR 1065 hydrochloride; Amifostine Thiol Dihydrochloride; WR-1065 dihydrochloride. CAS No. 14653-77-1. Molecular formula: C5H14N2S.2HCl. Mole weight: 207.16.
WR 1065
WR 1065. Group: Biochemicals. Grades: Purified. CAS No. 14653-77-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
WR99210
WR99210 is an orally active and low-toxicity dihydrofolate reductase (DHFR) inhibitor (IC50<0.075 nM). WR99210 shows good antiparasitic activity and is effective against P. falciparum and P. falciparum strains (including Pyrimethamine (HY-18062)-resistant P. falciparum strains) as well as T. gondii. Group: Inhibitors. Alternative Names: 1,6-Dihydro-6,6-dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,3,5-triazine-2,4-diamine. CAS No. 47326-86-3. Molecular formula: C14H18Cl3N5O2. Mole weight: 394.68. Appearance: Solid. Purity: 0.96. IUPACName: 6,6-dimethyl-1-[3-(2,4,5-trichlorophenoxy)propoxy]-1,3,5-triazine-2,4-diamine. Canonical SMILES: CC1 (N=C (N=C (N1OCCCOC2=C (C=C (C (Cl)=C2)Cl)Cl)N)N)C. Catalog: ACM47326863.
Wrightiin
Wrightiin is a new chlorinated depside from Erioderma wrightii Tuck (?Ascolichenes). CAS No. 107783-44-8. Molecular formula: C18H17ClO7. Mole weight: 380.78.
Wright's stain
25g Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials, Stains & Indicators. Formula: N/A. CAS No. 68988-92-1. Prepack ID 57163864-25g. See USA prepack pricing.
Wright's stain
Wright's stain. Group: Biochemicals. Alternative Names: Eosin Methylene blue according to Wright. Grades: Highly Purified. CAS No. 68988-92-1. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C36H27Br4N3O5S2. US Biological Life Sciences.
Worldwide
Wright's stain
Wright's stain is a hematologic stain that facilitates the differentiation of blood cell types. Wright's stain is classically a mixture of eosin (red) and methylene blue dyes. It is used primarily to stain peripheral blood smears, urine samples, and bone marrow aspirates. Wright's stain provides a manual or automated stain for bone marrow and peripheral blood smears [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 68988-92-1. Pack Sizes: 5 g; 10 g. Product ID: HY-W088068.
Wright Stain, 0.3% in Methyl Alcohol, Laboratory Grade, 100 mL
Storage Code: Red; flammable. Group: chem-category biological stains. Grades: chem-grade laboratory. Product ID: 898533. -- SOLD FOR EDUCATIONAL USE ONLY --
Wright Stain, 0.3% in Methyl Alcohol, Laboratory Grade, 500 mL
Storage Code: Red; flammable. Group: chem-category biological stains. Grades: chem-grade laboratory. Product ID: 898535. -- SOLD FOR EDUCATIONAL USE ONLY --
Wright Stain, Certified
Wright Stain, Certified. Group: Biochemicals. Grades: Certified Dye. Pack Sizes: 25g, 100g, 1Kg. US Biological Life Sciences.
Worldwide
Wrinkle Blur
Unique wrinkle-masking silicone elastomer powder with silica-treated coating. Unique composition absorbs fluid and enables the powder to flow freely without agglomeration, providing superior handling and processing ease. Note: Silica is amorphous, not crystalline. Because of this, a Prop 65 warning is not required. Uses: Pressed and loose powder, foundation powder, and compact powder, eye shadow, blush, lipstick, creams, lotions, sun care products. Group: Skin actives. CAS No. 156065-02-0/112945-52-5. Appearance: Fine, white powder. Catalog: CI-SC-0604.
Wrinkled Gianthyssop Herb Extract
Wrinkled Gianthyssop Herb Extract. Applications: Used for health care products, dietary supplements, herb medecine. Group: Others. Synonyms: Wrinkled Gianthyssop Herb Extract; Wrinkled Gianthyssop Herb L. Purity: 10:1 by TLC. Appearance: Brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Leaf. Species: Wrinkled Gianthyssop Herb L. Wrinkled Gianthyssop Herb Extract; Wrinkled Gianthyssop Herb L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-148.
WRN inhibitor 8
WRN inhibitor 8 (Example 224) is a WRN helicase inhibitor with IC 50 value of 48 nM. WRN inhibitor 8 can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3026502-95-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160859.
WRR483
WRR483 is a potent and selective cysteine protease inhibitor with trypanocidal activity in cell culture and animal model. It is an analogue of K-11777. It demonstrates good potency against cruzain with sensitivity to pH conditions and high efficacy in the cell culture assay. It also eradicates parasite infection in a mouse model of acute Chagas' disease. It binds covalently to the active site cysteine of the protease. It has potential to be developed as a treatment for Chagas disease. Uses: Wrr483 has potential to be developed as a treatment for chagas disease. Synonyms: WRR-483; WRR 483; WRR483. N-((S)-5-guanidino-1-oxo-1-(((S,E)-5-phenyl-1-(phenylsulfonyl)pent-1-en-3-yl)amino)pentan-2-yl)-4-methylpiperazine-1-carboxamide. Grades: >98%. CAS No. 1076088-50-0. Molecular formula: C29H41N7O4S. Mole weight: 583.75.
WRW4
WRW4, a specific formyl peptide receptor-like 1 (FPRL1) antagonist, inhibits WKYMVm binding to FPRL1 with an IC 50 of 0.23 μM. WRW4 specifically inhibits the increase in intracellular calcium by the FPRL1 agonists MMK-1, amyloid beta42 (Abeta42) peptide, and F peptide [1]. Uses: Scientific research. Group: Peptides. CAS No. 878557-55-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P1119.
WRW4
WRW4. Group: Biochemicals. Grades: Purified. CAS No. 878557-55-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
WRW4
WRW4 is a selective antagonist of formyl peptide receptor 2 (FPR2) signaling. WRW4 inhibits WKYMVm binding to FPR2 (IC50 = 0.23 μM) and blocks intracellular calcium release induced by WKYMVm, MMK 1, amyloid β42, and F peptide. Synonyms: WRW4; WRW 4; WRW-4. CAS No. 878557-55-2. Molecular formula: C61H65N15O6. Mole weight: 1104.28.
WRW4 TFA
WRW4 TFA is a selective antagonist of formyl peptide receptor 2 (FPR2) signaling. WRW4 inhibits WKYMVm binding to FPR2 (IC50 = 0.23 μM) and blocks intracellular calcium release induced by WKYMVm, MMK 1, amyloid β42, and F peptide. Synonyms: H-Trp-Arg-Trp-Trp-Trp-Trp-NH2.TFA; L-tryptophyl-L-arginyl-L-tryptophyl-L-tryptophyl-L-tryptophyl-L-tryptophanamide trifluoroacetic acid; WRW4 Trifluoroacetate; WRW4 (trifluoroacetate salt). Grades: ≥95%. Molecular formula: C63H66F3N15O8. Mole weight: 1218.29.
WS009 A
WS009 A is an endothelin receptor antagonists isolated from Streptomyces sp. no. 89009. II. The IC50 is 5.8 X 10(-6) mol/L. Synonyms: WS-009A. Molecular formula: C24H25NO10S. Mole weight: 519.52.
WS009 B
WS009 B is an endothelin receptor antagonists isolated from Streptomyces sp. no. 89009. II. The IC50 is 6.7 X 10(-7) mol/L. Synonyms: WS-009B. Molecular formula: C24H25NO11S. Mole weight: 535.52.
WS12
WS12 is a potent TRPM8 agonist. It acts as a cooling agent with EC50 value of 193 nM. It robustly activated TRPM8 in low micromolar concentrations, thus displaying a higher potency and efficacy compared to menthol. Uses: It is a good flotation agent for quartz and is also the most effective agent in asphalt emulsifier. it also can be used to waterproof and corrosion inhibitors and additive in petroleum products. and is an intermediate for the manufacture of amine salts, amine oxides, betaines, quaternaries, etc. it can be used in emollients, emulsifiers and foaming agents conditioners ,softeners, etc. it can be used for bath preparation, hair conditioner, skin care agent, shampoo, chemical compound, and cutting lubrication oil. Synonyms: WS 12; WS-12; WS12. (1R,2S)-2-isopropyl-N-(4-methoxyphenyl)-5-methylcyclohexane-1-carboxamide;(1R,2S,5R)-N-(4-methoxyphenyl)-5-methyl-2-propan-2-ylcyclohexane-1-carboxamide. Grades: 98%. CAS No. 68489-09-8. Molecular formula: C18H27NO2. Mole weight: 289.41.
WS 12
WS 12. Group: Biochemicals. Grades: Purified. CAS No. 68489-09-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
WS1279
WS1279 is a lipopeptide isolated from the fermentation broth of Streptomyces willmorei No. 1279. It stimulated the proliferation of mouse bone marrow cells in vitro and accelerated the recovery of granulocyte counts in bone marrow from leukopenia induced by mitomycin C (MMC) in mice. Synonyms: WS 1279; WS-1279; S-(2,3-bis(palmitoyloxy)propyl)-N-palmitoyl-L-cysteinyl-L-asparaginyl-L-serylglycylglycyl-L-serine. CAS No. 129712-27-2. Molecular formula: C68H125N7O15S. Mole weight: 1312.8.
WS 1358A1
WS 1358A1 is a dehydropeptide (DHP) inhibitor produced by Streptomyces parvulus. Synonyms: WS-1358A1. Molecular formula: C7H9NO7Na2. Mole weight: 265.13.
WS 1358B1
WS 1358B1 is a dehydropeptide (DHP) inhibitor produced by Streptomyces parvulus. Synonyms: WS-1358B1. CAS No. 117703-85-2. Molecular formula: C6H7NO7Na2. Mole weight: 251.1.
WS-2
Dye-Sensitized Solar Cell (DSSC). CAS No. 1263863-11-1. Catalog: ACM1263863111.
WS-5995 A is an anticoccidial antibiotic produced by Streptomyces auranticolor. Synonyms: Antibiotic WS5995A. Molecular formula: C19H12O6. Mole weight: 336.3.
WS-5995 B
WS-5995 B is an antibiotic produced by Streptomyces auranticolor. It exhibits weak ctivity against Proteus and trichomonas vaginalis. Synonyms: Antibiotic WS5995B. Molecular formula: C19H14O6. Mole weight: 338.3.
WS-5995 C
WS-5995 C is an anticoccidial antibiotic produced by Streptomyces auranticolor. Synonyms: Antibiotic WS5995C. Molecular formula: C19H14O7. Mole weight: 354.3.
WS6
WS6 is an IkB kinase and EBP1 inhibitor, with IC 50 values of 0.24 nM, 0.21 nM, and 40.48 nM in MV4-11, MOLM13, and K562 cells, respectively. WS6 promotes the proliferation of alpha and beta cells in the pancreas, has antioxidant and anti-inflammatory activities, and can alleviate depression like behavior in rats [1][2][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1421227-53-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12461.
WS6
WS6 induces R7T1 cell proliferation with EC50 of 0.28 μM, and promotes β cell proliferation in rodent and human primary islets. Synonyms: WS6; WS-6; WS 6. Grades: >98%. CAS No. 1421227-53-3. Molecular formula: C29H31F3N6O3. Mole weight: 568.59.
WS-7338 A
WS-7338 A is an endothelin receptor antagonist isolated from fermentation broth of Streptomyces sp. No. 7338. Molecular formula: C30H42N6O7. Mole weight: 598.7.
WS-7338 B
WS-7338 B is an endothelin receptor antagonist isolated from fermentation broth of Streptomyces sp. No. 7338. It showed good activity in an endothelin receptor binding assay with an IC50 of 2.7 x 10(-7) M. Molecular formula: C31H44N6O7. Mole weight: 612.72.
WS-7338 C
WS-7338 C is an endothelin receptor antagonist isolated from fermentation broth of Streptomyces sp. No. 7338. Molecular formula: C31H44N6O7. Mole weight: 612.72.
WS-7338 D
WS-7338 D is an endothelin receptor antagonist isolated from fermentation broth of Streptomyces sp. No. 7338. Molecular formula: C29H40N6O7. Mole weight: 584.7.
WS-7528
WS-7528 is produced by Streptomyces sp. No. 7528. It inhibited estrogen binding to its receptor protein in rat uterine cytosol. Synonyms: WS 7528; WS7528; BE-14348B. CAS No. 132147-69-4. Molecular formula: C16H14O5. Mole weight: 286.28.
WS75624 A
WS75624 A is an endothelin converting enzyme (ECE) inhibitor isolated from the fermentation broth of Saccharothrix sp. No. 75624. It also showed other metalloprotease (collagenase and neutral endopeptidase) inhibitory activity with IC50 value of 1 mM/ml. Synonyms: WS-75624 A; WS 75624 A; WS-75624A. Molecular formula: C18H24N2O5S. Mole weight: 380.5.