A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Xanthorrhizol Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H19D3O. Mole Weight: 221.36. Catalog: APB11210.
Xanthorrhizol Impurity 2
Xanthorrhizol Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 915301-61-0. Molecular Formula: C15H26O2. Mole Weight: 2398.37. Catalog: APB915301610.
Xanthorrhizol Impurity 3
Xanthorrhizol Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 915235-16-4. Molecular Formula: C14H22O2. Mole Weight: 222.33. Catalog: APB915235164.
Xanthorrhizol Impurity 4
Xanthorrhizol Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 196193-23-4. Molecular Formula: C14H22O. Mole Weight: 206.33. Catalog: APB196193234.
Xanthorrhizol Impurity 5
Xanthorrhizol Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C14H22O2. Mole Weight: 222.33. Catalog: APB11205.
Xanthorrhizol Impurity 6
Xanthorrhizol Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C14H22O3. Mole Weight: 239.33. Catalog: APB11206.
Xanthorrhizol Impurity 7
Xanthorrhizol Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C15H22O. Mole Weight: 218.34. Catalog: APB11207.
Xanthorrhizol Impurity 8
Xanthorrhizol Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C14H24O2. Mole Weight: 224.34. Catalog: APB11209.
Xanthorrhizol Impurity 9
Xanthorrhizol Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C17H30O2Si. Mole Weight: 294.51. Catalog: APB11208.
Xanthosine
Xanthosine is a nucleoside derived from xanthine and ribose. Xanthosine can increase mammary stem cell population and milk production in cattle and goats [1]. Uses: Scientific research. Group: Natural products. CAS No. 146-80-5. Pack Sizes: 10 mM * 1 mL; 50 mg. Product ID: HY-W011527.
Xanthosine
The deamination product of Guanosine. Potential biomarker for detecting radiation exposure. Used in the amplification of DNA isothermal strand displacement. Synonyms: Xanthine riboside; 9-beta-D-Ribofuranosylxanthine; Beta-D-Ribofuranoside, xanthine-9; AI3-52693. Grades: >98.0%. CAS No. 146-80-5. Molecular formula: C10H12N4O6. Mole weight: 284.23.
Xanthosine
The deamination product of Guanosine. Potential biomarker for detecting radiation exposure. Used in the amplification of DNA isothermal strand displacement. Group: Biochemicals. Alternative Names: 3,9-Dihydro-9- β-D-ribofuranosyl-1H-purine-2,6-dione; Xanthine Riboside;9- β-D-Ribofuranosylxanthine; NSC 18930; Xanthine-9 β-D-Ribofuranoside. Grades: Highly Purified. CAS No. 146-80-5. Pack Sizes: 2g, 5g, 10g, 25g, 50g. US Biological Life Sciences.
Worldwide
Xanthosine-5'-monophosphate ammonium salt
Xanthosine-5'-monophosphate ammonium salt, a highly esteemed compound in the biomedical industry, aptly fulfills a pivotal function in the therapeutic approach of specific ailments. Furthermore, it serves as a vital precursor for the synthesis of diverse pharmaceuticals, showcasing its indispensable role. Synonyms: 9-(5-O-Phosphonopentofuranosyl)-9H-purine-2,6-diol. CAS No. 523-98-8. Molecular formula: C10H13N4O9P. Mole weight: 364.21.
Xanthosine 5'-monophosphate disodium salt
Xanthosine is a guanosine derivative and has been found to be effective as a biomarker for detecting radiation exposure. Synonyms: 5'-Xanthylic Acid Disodium Salt; Xmp Disodium salt; L-XMP Sodium; Disodium ((2R,3S,4R,5R)-5-(2,6-dihydroxy-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate. Grades: ≥95% by HPLC. CAS No. 25899-70-1. Molecular formula: C10H11N4Na2O9P. Mole weight: 408.17.
Xanthosine 5'-monophosphate disodium salt
Xanthosine 5'-monophosphate disodium salt. CAS No: 25899-70-1
Sarchem Laboratories New Jersey NJ
Xanthosine 5'-monophosphate Disodium Salt
Xanthosine 5-Monophosphate as chameleon-like nucleotide. Group: Biochemicals. Alternative Names: 5'-Xanthylic Acid Disodium Salt. Grades: Highly Purified. CAS No. 25899-70-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C10H11N4Na2O9P, Molecular Weight: 408.17. US Biological Life Sciences.
Xanthosine 5'-(trihydrogen diphosphate), trisodium salt
Cas No. 84215-50-9. Molecular formula: C10H11N4Na3O12P2. Mole weight: 510.130772.
Xanthosine-5'-Triphosphate
Xanthosine-5'-Triphosphate, known as XTP, holds immense significance within the biomedical sector. It serves as an essential building block for RNA and DNA synthesis, thereby playing a pivotal role in genetic material generation. Its versatility extends to governing crucial cellular operations like protein synthesis, signaling pathways, and enzymatic reactions. Synonyms: Xanthosine-TP. Grades: ≥ 95 % by HPLC. CAS No. 6253-56-1. Molecular formula: C10H15N4O15P3(free acid). Mole weight: 524.16 (free acid).
Xanthosine dihydrate
Xanthosine Dihydrate is a multifaceted compound widely employed as a pivotal intermediary compound in the intricate process of synthesizing highly potent antiviral drugs, exemplified by oxymetacrine. This exceptional compound exhibits its profound applications in studying an extensive range of virulent infections, most notably the infamous hepatitis C, through its remarkable capability to impede viral replication. Synonyms: UNII-1U62I480SP; MFCD00149347; ST51007290. Grades: 95%. CAS No. 5968-90-1. Molecular formula: C10H12N4O6.2H2O. Mole weight: 320.258.
Xanthosine Dihydrate
The deamination product of Guanosine. Potential biomarker for detecting radiation exposure. Used in the amplification of DNA isothermal strand displacement. Group: Biochemicals. Alternative Names: 3,9-Dihydro-9- β-D-ribofuranosyl-1H-purine-2,6-dione Dihydrate; Xanthine Riboside Dihydrate;9- β-D-Ribofuranosylxanthine Dihydrate; NSC 18930 Dihydrate; Xanthine-9 β-D-Ribofuranoside Dihydrate. Grades: Highly Purified. CAS No. 5968-90-1. Pack Sizes: 2g, 5g, 10g, 25g, 50g. US Biological Life Sciences.
Worldwide
Xanthothricin
It is a nitrogenous heterocyclic antibiotic produced by the strain of Str. sp. and Pseudomonas cocovenenans. It has anti-bacterial and mycobacterium effects. Synonyms: Toxoflavin; Toxoflavine; Pyrimido(5,4-e)-1,2,4-triazine-5,7-(1H,6H)-dione, 1,6-dimethyl-; 1-methylreumycin; Fervenuline; GNF-PF-67. Grades: >98% by HPLC. CAS No. 84-82-2. Molecular formula: C7H7N5O2. Mole weight: 193.16.
Xanthotol (Xanthotoxol)
Xanthotol (Xanthotoxol). Group: Biochemicals. Grades: Plant Grade. CAS No. 2009-24-7. Pack Sizes: 20mg. Molecular Formula: C11H6O4, Molecular Weight: 202.16. US Biological Life Sciences.
Worldwide
Xanthotoxin (8-Methoxypsoralen)
Xanthotoxin (8-Methoxypsoralen). Group: Biochemicals. Alternative Names: Zanthotoxin; Ammoidin; Meloxine; Methoxa-Dome; Geroxalen; Oxsoralen; Puvalen; Puvamet; Methoxalen. Grades: Plant Grade. CAS No. 298-81-7. Pack Sizes: 20mg. Molecular Formula: C12H8O4, Molecular Weight: 216.19. US Biological Life Sciences.
Worldwide
Xanthotoxol
A hydroxylated psoralen that inhibits neutrophil infiltration and brain edema induced by focal cerebral ischemia-reperfusion injury in rats. A potentially useful antiarrhythmic agent. It has been shown to be effective in the prevention of ventricular fibrillation of mice induced by chloroform, of rats induced by calcium chloride, and in treatment of rat arrhythmia induced by aconitine. Recent studies show that it may also have antioxidant and anticancer activities. Group: Biochemicals. Alternative Names: 9-Hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 6,7-Dihydroxy-5-benzofuranacrylic Acid δ-Lactone; 3-(6,7-Dihydroxy-5-benzofuranyl)-2-propenoic Acid δ-Lactone; 8-Hydroxypsoralen; NSC 401269. Grades: Highly Purified. CAS No. 2009-24-7. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
xanthoxin dehydrogenase
Requires a molybdenum cofactor for activity. NADP+ cannot replace NAD+ and short-chain alcohols such as ethanol, isopropanol, butanol and cyclohexanol cannot replace xanthoxin as substrate. Involved in the abscisic-acid biosynthesis pathway in plants, along with EC 1.2.3.14 (abscisic-aldehyde oxidase), EC 1.13.11.51 (9-cis-epoxycarotenoid dioxygenase) and EC 1.14.13.93 [(+)-abscisic acid 8'-hydroxylase]. Abscisic acid is a sesquiterpenoid plant hormone that is involved in the control of a wide range of essential physiological processes, including seed development, germination and responses to stress. Group: Enzymes. Synonyms: xanthoxin oxidase; ABA2. Enzyme Commission Number: EC 1.1.1.288. CAS No. 129204-37-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0196; xanthoxin dehydrogenase; EC 1.1.1.288; 129204-37-1; xanthoxin oxidase; ABA2. Cat No: EXWM-0196.
Xanthoxoline
Xanthoxoline is an acidic chemical substance. It has been shown to have anti-cancer properties in vivo in animal models and cell cultures. Xanthoxoline inhibits the growth of leukemia cells by binding to DNA, preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Xanthoxoline also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.br>br>. Group: Other alkaloids. CAS No. 17014-43-6. Molecular formula: C15H13NO4. Mole weight: 271.27 g/mol. Canonical SMILES: COC1=C (C (=C2C (=C1)NC3=CC=CC=C3C2=O)O)OC. Catalog: ACM17014436.
Xanthurenic acid
Xanthurenic acid is a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus. Uses: Scientific research. Group: Natural products. CAS No. 59-00-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W014666.
Xanthurenic acid
Xanthurenic acid acts as an endogenous Group II metabotropic glutamate receptor (mGluR2 and mGluR3) agonist in transfected HEK293 cells at nanomolar concentrations. It suppresses cAMP formation in mouse cortical slices expressing mGlu2 and mGlu3 receptors. Uses: Hypolipidemic agents. Synonyms: 8-hydroxy-4-oxo-1H-quinoline-2-carboxylic acid. Grades: ≥ 98 % by HPLC. CAS No. 59-00-7. Molecular formula: C10H7NO4. Mole weight: 205.17.
Xanthurenic Acid
Excreted by pyridoxine-deficient animals after the ingestion of tryptophan. Group: Biochemicals. Alternative Names: 4,8-Dihydroxy-2-quinolinecarboxylic Acid; 4,8-Dihydroxyquinaldic Acid; 8-Hydroxykynurenic Acid; NSC 401570; Xanthuric Acid. Grades: Highly Purified. CAS No. 59-00-7. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Xanthurenic Acid-d4
Labeled Xanthurenic Acid. Excreted by pyridoxine-deficient animals after the ingestion of tryptophan. Group: Biochemicals. Alternative Names: 4,8-Dihydroxy-2-quinolinecarboxylic Acid-d4; 4,8-Dihydroxyquinaldic Acid-d4; 8-Hydroxykynurenic Acid-d4; NSC 401570-d4; Xanthuric Acid-d4. Grades: Highly Purified. CAS No. 1329611-28-0. Pack Sizes: 2.5mg. Molecular Formula: C10H3D4NO4, Molecular Weight: 209.19. US Biological Life Sciences.
Worldwide
Xanthydrol
Intermediate in the preparation of Propantheline Bromide. Group: Biochemicals. Grades: Highly Purified. CAS No. 90-46-0. Pack Sizes: 1g, 5g, 10g, 25g, 100g. Molecular Formula: C??H??O?. US Biological Life Sciences.
Heterocyclic Organic Compound. CAS No. 102262-31-7. Catalog: ACM102262317.
X antigen family member 1 (17-32)
X antigen family member 1 (17-32) is a bioactive peptide of X antigen family member 1. The transcription of XAGE1A is regulated by methylation of the CpG island in the promoter. Synonyms: Cancer/testis antigen 12.1 (17-32); G antigen family D member 2 (17-32).
X antigen family member 1 (21-29)
X antigen family member 1 (21-29) is a bioactive peptide of X antigen family member 1. The transcription of XAGE1A is regulated by methylation of the CpG island in the promoter. Synonyms: Cancer/testis antigen 12.1 (21-29); G antigen family D member 2 (21-29).
X antigen family member 1 (33-49)
X antigen family member 1 (33-49) is a bioactive peptide of X antigen family member 1. The transcription of XAGE1A is regulated by methylation of the CpG island in the promoter. Synonyms: Cancer/testis antigen 12.1 (33-49); G antigen family D member 2 (33-49).
Xantocillin is a marine agent extracted from Penicillium commune. Group: Heterocyclic organic compound. Alternative Names: 4,4'-(2,3-Diisocyano-1,3-butadiene-1,4-diyl)bisphenol. CAS No. 580-74-5. Molecular formula: C18H12N2O2. Mole weight: 288.3. Purity: 95%+. IUPACName: 4-[(1Z,3Z)-4-(4-Hydroxyphenyl)-2,3-diisocyanobuta-1,3-dienyl]phenol. Canonical SMILES: [C-]#[N+]C (=CC1=CC=C (C=C1)O)C (=CC2=CC=C (C=C2)O)[N+]#[C-]. Density: 1.2396 g/cm³. Catalog: ACM580745.
Xantphos
Xantphos (9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene) is a biochemical reagent that can be used as a biological material or organic compound for life science related research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: 9,9-Dimethyl-4,5-bis(diphenylphosphino)xanthene. CAS No. 161265-03-8. Pack Sizes: 25 g. Product ID: HY-Y0091.
XAP044
XAP044 is a potent and selective antagonist of mGlu7. The metabotropic glutamate receptor subtype 7 (mGlu7) is an important presynaptic regulator of neurotransmission in the mammalian CNS. XAP044 demonstrates good brain exposure and wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral paradigms [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 196928-50-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-110146.
XAP 044
XAP 044. Group: Biochemicals. Grades: Purified. CAS No. 196928-50-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
XAP 044
XAP 044 is a potent, selective and brain penetrating mGlu7 antagonist (IC50 = 88 nM). It inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice. XAP 044 exhibits anti-anxiety effects in rodent models and can be potentially used in the treatment of anxiety and depression. Synonyms: XAP044; XAP 044; XAP-044; 7-Hydroxy-3-(4-iodophenoxy)-4H-1-benzopyran-4-one. Grades: ≥98% by HPLC. CAS No. 196928-50-4. Molecular formula: C15H9IO4. Mole weight: 380.13.
XAV939
XAV 939 is a tankyrase (TNKS) inhibitor with IC50 values of 11 nM and 4 nM for tankyrase 1 and 2 respectively. XAV 939 antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin. It also suppresses proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1. Uses: Differentiation. Synonyms: XAV939; XAV 939; XAV-939. 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one. Grades: 0.98. CAS No. 284028-89-3. Molecular formula: C14H11F3N2OS. Mole weight: 312.31.
XAV 939
A tankyrase (TNKS) inhibitor that antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin. XAV 939 inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1. Group: Biochemicals. Alternative Names: 1, 5, 7, 8-Tetrahydro-2-[4- (trifluoromethyl) phenyl]-4H-thiopyrano[4, 3-d]pyrimidin-4-one; NVP-XAV 939. Grades: Highly Purified. CAS No. 284028-89-3. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
XAV-939
XAV-939 is a Tankyrase inhibitor. XAV-939 has inhibitory activity for TNKS1 and TNKS2 with IC 50 values of 5 nM and 2 nM, respectively. XAV-939 also is an enhancer of osteoblastic differentiation of hMSCs. XAV-939 can be used for the research of conditions associated with activated Wnt signaling, such as cancer, fibrotic diseases and conditions associated with low bone formation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 284028-89-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15147.
A Tankyrase (TNKS) inhibitor (IC50 = 110nM for TNKS1 and 4nM for TNKS2). Antagonizes wnt signaling via stimulation of beta-catenin degradation and stabilization of axin. Inhibits proliferation of the mu-catenin-dependent colon carcinoma cell line DLD-1. Group: Biochemicals. Alternative Names: 3, 5, 7, 8-Tetrahydro-2-[4- (trifluoromethyl) phenyl]-4H-thi opyrano[4,3-d]pyrimidin-4-one. Grades: Highly Purified. CAS No. 284028-89-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Xba I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (dam-/HindIII-digest) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 2000U; 10000U. T↑CTAGA AGATC↓T. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer O, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene XbaI from Xanthomonas badrii. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 50% glycerol. Cat No: ET-1188RE.
XCC
XCC. Group: Biochemicals. Grades: Purified. CAS No. 96865-83-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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XCC
XCC is an adenosine receptor antagonist (Ki = 42, 68 and 1130 nM for A1, A2B and A2A receptors). Synonyms: 2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetic acid. Grades: ≥98% by HPLC. CAS No. 96865-83-7. Molecular formula: C19H22N4O5. Mole weight: 386.4.
XCT 0315908
XCT 0315908, a RXR agonist, showed selectivity for RXR-Nurr1 over a broad range of other RXR dimerization partners but with rather low potency. Uses: A rxr agonist. Synonyms: XCT0135908; XCT-0135908; XCT 0135908. 4-[(5-Allyl-6-methyl-2-phenyl-4-pyrimidinyl)amino]benzoic acid; 4-[(5-Allyl-6-methyl-2-phenyl-4-pyrimidinyl)amino]benzoic acid. Grades: ≥96%. CAS No. 300837-31-4. Molecular formula: C21H19N3O2. Mole weight: 345.39.
XCT790
XCT-790 is a potent and selective inverse agonist for ERRα with an IC 50 value of 0.37 μM. XCT-790 induces cell death in chemotherapeutic resistant cancer cells. XCT-790 (Compound 12) is inactive against ERRγ and the estrogen receptors ERα and ERβ [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 725247-18-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-10426.
XCT 790
XCT 790. Group: Biochemicals. Grades: Purified. CAS No. 725247-18-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
XCT 790
XCT-790 is a potent, selective ERRα antagonist/inverse agonist (IC50 = ~400 nM), displaying no antagonist activity at ERRγ or ERα at concentrations below 10 μM. Uses: Selective errα antagonist/inverse agonist. Synonyms: XCT790; XCT 790; XCT-790; 3-[4-(2,4-Bis-trifluoromethylbenzyloxy)-3-methoxyphenyl]-2-cyano-N-(5-trifluoromethyl-1,3,4-thiadiazol-2-yl)acrylamide; (E)-3-[4-[[2,4-bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyano-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]prop-2-enamide. Grades: ≥98%. CAS No. 725247-18-7. Molecular formula: C23H13F9N4O3S. Mole weight: 596.42.
XD 14
XD 14 is a BET bromodomain inhibitor (Kd = 160, 170, 380, 490, 830 and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2) respectively). XD 14 also inhibits BRDT(1), CBP, p300 and BRDT(2) (Kd = 1.2, 1.6, 2.6 and 3.7 μM, respectively). XD 14 inhibits proliferation of HL-60 leukemia cells in vitro. Synonyms: XD14; XD 14; XD-14; 4-Acetyl-N-[5-[(diethylamino)sulfonyl]-2-hydroxyphenyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide. Grades: ≥98% by HPLC. CAS No. 1370888-71-3. Molecular formula: C20H27N3O5S. Mole weight: 421.51.
XDP
XDP is an extraordinary chemical compound, used for studying a myriad of cancer types. Exerting unparalleled anticancer prowess, it orchestrates a symphony of inhibitory actions, suppressing cellular proliferation while ceremoniously evoking apoptosis. Synonyms: Xanthosine-5'-diphosphate, Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 29042-61-3. Molecular formula: C10H14N4O12P2(free acid). Mole weight: 444.18 (free acid).
XE 991
XE 991 is a KCNQ channel and M-current blocker potentially for the treatment of AD. Uses: Potential treatment of ad. Synonyms: XE-991; LS-190926; XE 991; LS 190926; XE991; LS190926; 10,10-bis(pyridin-4-ylmethyl)anthracen-9-one. Grades: 99%. CAS No. 122955-42-4. Molecular formula: C26H20N2O. Mole weight: 376.45.
XE 991 dihydrochloride
XE 991 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 122955-13-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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XE 991 dihydrochloride
XE 991 dihydrochloride is a potent and selective blocker of KV7 (KCNQ) voltage-gated potassium channels. XE 991 blocks KV7.2+7.3 (KCNQ2+3) / M-currents (IC50 = 0.6 - 0.98 μM) and KV7.1 (KCNQ1) homomeric channels (IC50 = 0.75 μM) but is less potent against KV7.1/minK channels (IC50 = 11.1 μM). XE 991 increases hippocampal ACh release and enhances cognition following oral administration in vivo, suggesting to be beneficial for Alzheimer's disease therapy. Uses: Potential treatment of alzheimer's disease. Synonyms: XE991; XE 991; XE-991; LS 190926; LS190926; LS-190926; 10,10-bis(4-Pyridinylmethyl)-9(10H)-anthracenone dihydrochloride. Grades: ≥99% by HPLC. CAS No. 122955-13-9. Molecular formula: C26H20N2O.2HCl. Mole weight: 449.37.
XE991 dihydrochloride
XE991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1) , Kv7.2 (KCNQ2) , Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC 50 s of 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 122955-13-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108577.
Xeligekimab
Xeligekimab (GR 1501) is an anti- human interleukin 17A (IL-17A) humanized monoclonal antibody. Xeligekimab inhibits the pro-inflammatory cascade [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GR 1501. CAS No. 2382921-73-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99515.
XEN445
XEN445 is potent and selective endothelial lipase inhibitor, that showed good ADME and PK properties, and demonstrated in vivo efficacy in raising plasma HDLc concentrations in mice. Endothelial lipase (EL) activity has been implicated in HDL metabolism and in atherosclerotic plaque development; inhibitors are proposed to be efficacious in the treatment of dyslipidemia related cardiovascular disease. Group: Inhibitors. Alternative Names: XEN445; XEN 445; XEN-445. CAS No. 1515856-92-4. Molecular formula: C18H17F3N2O3. Mole weight: 366.33. Appearance: White to off-white solid powder. Purity: >98%. IUPACName: (S)-2-(3-(pyridin-2-ylmethoxy)pyrrolidin-1-yl)-5-(trifluoromethyl)benzoic acid. Canonical SMILES: O=C (O)C1=CC (C (F) (F)F)=CC=C1N2C[C@@H] (OCC3=NC=CC=C3)CC2. Catalog: ACM1515856924.
XEN445
XEN445 is a potent and selective endothelial lipase inhibitor with IC50 of 0.237 μM. Synonyms: XEN445; XEN 445; XEN-445. Grades: >98%. CAS No. 1515856-92-4. Molecular formula: C18H17F3N2O3. Mole weight: 366.33.
XEN907
XEN907 is a novel spirooxindole NaV1.7 blocker with IC50 of 3 nM. It shows a further 10-fold increase in potency, which represents a promising structure for further optimization efforts in vitro. It shows no significant activity at 10 μM against a broad panel of 63 receptors and transporters. It is extensively distributed and rapidly cleared. Uses: Xen907 is used as a spirooxindole blocker. Synonyms: XEN907; XEN 907; XEN-907;1'-pentylspiro[6H-furo[2,3-f][1,3]benzodioxole-7,3'-indole]-2'-one. Grades: >98%. CAS No. 912656-34-9. Molecular formula: C21H21NO4. Mole weight: 351.40.
Xenin
Xenin is a 25-amino acid peptide initially isolated from human gastric mucosa. Xenin is a gut hormone that can reduce food intake. Uses: Scientific research. Group: Peptides. CAS No. 144092-28-4. Pack Sizes: 500 μg; 5 mg; 10 mg. Product ID: HY-P0259.
Xenin
Xenin, a 25-amino acid peptide initially isolated from human gastric mucosa, has 6 C-terminal amino acids in common with amphibian xenopsin. Xenin may stimulate the enzyme release from the exocrine pancreas. Synonyms: Xenin-25; L-Methionyl-L-leucyl-L-threonyl-L-lysyl-L-phenylalanyl-L-α-glutamyl-L-threonyl-L-lysyl-L-seryl-L-alanyl-L-arginyl-L-valyl-L-lysylglycyl-L-leucyl-L-seryl-L-phenylalanyl-L-histidyl-L-prolyl-L-lysyl-L-arginyl-L-prolyl-L-tryptophyl-L-isoleucyl-L-leucine; Human Xenin. CAS No. 144092-28-4. Molecular formula: C139H224N38O32S. Mole weight: 2971.57.
Xenin 8
Xenin 8. Group: Biochemicals. Grades: Purified. CAS No. 117442-28-1. Pack Sizes: 1mg. US Biological Life Sciences.