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| Product | Description | |
|---|---|---|
| Xenin 8 | Xenin 8, a C-terminal fragment of xenin, can modulate pancreatic insulin and glucagon secretion/effects. Xenin 8 stimulates basal and arginine-induced insulin secretion and potentiates the insulin response to glucose (EC50 = 0.16 nM). Synonyms: Xenopsin-related peptide 1; XP-1. CAS No. 117442-28-1. Molecular formula: C51H79N15O9. Mole weight: 1046.28. |  |
| Xenin 8 acetate | Xenin-8, a C-terminal octapeptide, is a biologically active fragment of Xenin. Xenin-8 stimulates basal insulin secretion and potentiates the insulin response to glucose in a dose-dependent manner (EC50=0.16 nM). Molecular formula: C53H83N15O11. Mole weight: 1106.32. | |
| xenobiotic-transporting ATPase | ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. The enzyme from Gram-positive bacteria and eukaryotic cells export a number of drugs, with unusual specificity, covering various groups of unrelated substances, while ignoring some that are closely related structurally. Several distinct enzymes may be present in a single eukaryotic cell. Many of them transport glutathione-drug conjugates. Some also show some 'flippase' (phospholipid-translocating ATPase; EC 3.6.3.1) activity. Group: Enzymes. Synonyms: multidrug-resistance protein; MDR protein; P-glycoprotein; pleiotropic-drug-resistance protein; PDR protein; steroid-transporting ATPase; ATP phosphohydrolase (steroid-exporting). Enzyme Commission Number: EC 7.6.2.2 (Formerly EC 3.6.3.44). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4683; xenobiotic-transporting ATPase; EC 3.6.3.44; multidrug-resistance protein; MDR protein; P-glycoprotein; pleiotropic-drug-resistance protein; PDR protein; steroid-transporting ATPase; ATP phosphohydrolase (steroid-exporting). Cat No: EXWM-4683. |  |
| Xenocockiamide A | Molecular formula: C18H22N2. Mole weight: 266.38. | |
| Xenocockiamide B | Molecular formula: C27H28N2O. Mole weight: 396.52. | |
| Xenocockiamide C | Molecular formula: C36H34N2O2. Mole weight: 526.67. | |
| Xenocockiamide D | Molecular formula: C34H32N2O2. Mole weight: 500.63. | |
| Xenon difluoride | 99.99% trace metals basis. Uses: For analytical and research use. Group: Electronic chemicals. CAS No. 13709-36-9. Pack Sizes: 1G, 5G. Mole Weight: 169.29. EC Number: 237-251-2. Catalog: AP13709369. Assay: 99.99% trace metals basis. |  |
| Xenopsin | Xenopsin, the neurotensin-like octapeptide from Xenopusskin at the carboxyl terminus of its precursor, shows sequence homology to mammalian neurotensin and shares a number of its biological properties. Synonyms: H-Pyr-Gly-Lys-Arg-Pro-Trp-Ile-Leu-OH; 5-oxo-L-prolylglycyl-L-lysyl-L-arginyl-L-prolyl-L-tryptophyl-L-isoleucyl-L-leucine. Grades: >98%. CAS No. 51827-01-1. Molecular formula: C47H73N13O10. Mole weight: 980.16. | |
| Xenopsin 2TFA | Xenopsin 2TFA is a neurotensin-like octapeptide previously isolated from amphibian skin. Synonyms: H-Pyr-Gly-Lys-Arg-Pro-Trp-Ile-Leu-OH.2TFA; L-pyroglutamyl-glycyl-L-lysyl-L-arginyl-L-prolyl-L-tryptophyl-L-isoleucyl-L-leucine trifluoroacetic acid; 5-Oxo-L-prolylglycyl-L-lysyl-L-arginyl-L-prolyl-L-tryptophyl-L-isoleucyl-L-leucine trifluoroacetate; Xenopsin trifluoroacetate; L-Leucine, N-[N-[N-[1-[N2-[N2-[N-(5-oxo-L-prolyl)glycyl]-L-lysyl]-L-arginyl]-L-prolyl]-L-tryptophyl]-L-isoleucyl]-, trifluoroacetate (1:2); Xenopsin (Xenopus amieti) trifluoroacetate. Grades: ≥95%. Molecular formula: C51H75F6N13O14. Mole weight: 1208.23. | |
| Xenopsin precursor fragment | Xenopsin precursor fragment is an antibacterial peptide isolated from Xenopus laevis. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: XPF; Gly-Trp-Ala-Ser-Lys-Ile-Gly-Gln-Thr-Leu-Gly-Lys-Ile-Ala-Lys-Val-Gly-Leu-Lys-Glu-Leu-Ile-Gln-Pro-Lys. Grades: >96%. Molecular formula: C123H211N33O32. Mole weight: 2664.23. | |
| Xenopsin-Related Peptide 2 (XP-2) | Heterocyclic Organic Compound. Alternative Names: Xenopsin-Related Peptide 2 (XP-2). CAS No. 117442-29-2. Catalog: ACM117442292. |  |
| Xenorhabdin I | Xenorhabdin is a dithiopyrrolidone antibiotic isolated from Xenorhabdus bovienii. It has antimicrobial and insecticidal activity. CAS No. 92680-94-9. Molecular formula: C11H14N2O2S2. Mole weight: 270.37. | |
| Xenovulene A | It is produced by the strain of Acremonium strcturn. It has the effect of inhibiting the binding of Flunitrazepam to γ-aminobutyric acid-benzodiazapine with IC50 of 40 nmol/L. Synonyms: (2aR, 5aR, 11E, 14aS, 14bS, 14cS) -4-Hydroxy-5a, 9, 9, 12-tetramethyl-2a, 5a, 6, 9, 10, 13, 14, 14a, 14b, 14c-decahydro-1, 5-dioxacyclopenta [cd]cycloundeca [f]inden-3 (2H) -one. Molecular formula: C22H30O4. Mole weight: 358.47. | |
| Xenoy | Xenoy. Group: Polymers. |  |
| Xentuzumab | Xentuzumab (Anti-Human IGF1 and IGF2 Recombinant Antibody; BI836845) is a recombinant a human monoclonal antibody that targets IGF ligands IGF1 and IGF2. Xentuzumab inhibits both of IGF1 and IGF2 growth-promoting signalling and suppresses AKT activation [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BI 836845; Anti-Human IGF1 and IGF2 Recombinant Antibody. CAS No. 1417158-65-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99274. |  |
| Xeroboside | Cas No. 117842-09-8. | |
| Xeruborbactam | Xeruborbactam is an extended-spectrum inhibitor of serine and metal-β-lactamase. Synonyms: QPX7728; QPX-7728; QPX 7728; (1aR, 7bS)-5-fluoro-2-hydroxy-1, 1a, 2, 7b-tetrahydrocyclopropa[c][1, 2]benzoxaborinine-4-carboxylic acid; Benzo[e]cycloprop[c][1,2]oxaborin-4-carboxylic acid, 5-fluoro-1,1a,2,7b-tetrahydro-2-hydroxy-, (1aR,7bS)-carboxylic acid. Grades: >98%. CAS No. 2170834-63-4. Molecular formula: C10H8BFO4. Mole weight: 221.98. | |
| Xestospongin c | Xestospongin C ((-)-Xestospongin C) is a selective, reversible inositol 1,4,5-trisphosphate receptor (IP3R) inhibitor. Xestospongin C acts as an inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) pump of internal stores. Xestospongin C blocks IP3-induced Ca2+ release from cerebellar microsomes with an IC50 of 358 nM. Xestospongin C is a valuable tool for investigating the structure and function of IP3Rs and Ca2+ signaling in neuronal and nonneuronal cells. Group: Inhibitors. Alternative Names: [1R-(1R*, 4AR*, 11R*, 12AS*, 13S*, 16AS*, 23R*, 24AS*)]-EICOSAHYDRO-5H, 17H-1, 23:11, 13-DIETHANO-2H, 14H-[1, 11]DIOXACYCLOEICOSINO[2, 3-B:12, 13-B]DIPYRIDINE; (1R, 4aR, 11R, 12aS, 13S, 16aS, 23R, 24aS)-Eicosahydro-5H, 17H-1, 23:11, 13-diethano-2H, 14H-[1, 11]dioxacycloeicosino[2. CAS No. 88903-69-9. Molecular formula: C28H50N2O2. Mole weight: 446.71. Appearance: off-white. Purity: 0.96. IUPACName: XESTOSPONGIN C. Density: 1.06g/cm³. Catalog: ACM88903699. | |
| Xevinapant | Xevinapant (AT-406) is a potent and orally bioavailable Smac mimetic and an antagonist of IAPs , and it binds to XIAP, cIAP1, and cIAP2 proteins with K i of 66.4, 1.9, and 5.1 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT-406; Debio 1143; SM-406. CAS No. 1071992-99-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15454. | |
| Xevinapant | Xevinapant Inhibitor. Uses: Scientific use. Product Category: T6763. CAS No. 1071992-99-8. |  |
| Xevinapant hydrochloride | Xevinapant (AT-406) hydrochloride is a potent and orally bioavailable Smac mimetic and an antagonist of the inhibitor of apoptosis proteins (IAPs). Xevinapant hydrochloride binds to XIAP, cIAP1, and cIAP2 proteins with K i s of 66.4, 1.9, and 5.1 nM, respectively. Xevinapant hydrochloride effectively antagonizes XIAP BIR3 protein in a cell-free functional assay, induces rapid degradation of cellular cIAP1 protein, and inhibits cancer cell growth in various human cancer cell lines. Xevinapant hydrochloride is highly effective in induction of apoptosis in xenograft tumors [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AT-406 hydrochloride; Debio 1143 hydrochloride; SM-406 hydrochloride. CAS No. 1071992-57-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13208. | |
| XG 102 | XG-102 is a TAT-conjugated dextrose peptide that inhibits c-Jun N-terminal kinase, and has the potential to treat intraocular inflammation. Synonyms: AM 111; XG 102 peptide; D-JNKI-1. CAS No. 1198367-70-2. Molecular formula: C164H285N65O41. Mole weight: 3823.49. | |
| X-Gal | X-Gal is a fluorecent substrate for β-galactosidase and blue-white selection of recombinant bacterial colonies with the lac+ genotype. Synonyms: 5-Bromo-4-chloro-3-indolyl β-D-galactopyranoside; X-b-D-Galactoside; BCIG. CAS No. 7240-90-6. Molecular formula: C14H15BrClNO6. Mole weight: 408.64. | |
| X-GAL | X-GAL (BCIG) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity [1] [2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: BCIG. CAS No. 7240-90-6. Pack Sizes: 200 mg; 500 mg; 1 g; 2 g. Product ID: HY-15934. | |
| X-Gal, 40mg/ml in DMF (5-Bromo-4-chloro-3-indolyl-b-D-galactoside galactopyranoside, Xgal) | Blue substrate used in the detection of b-galactosidase in bacteria or phage as a selection agent for cloning experiments utilizing the lacZ vector. Colonies expressing b-galactosidase will appear blue in the presence of XGAL. Others will appear white. Group: Biochemicals. Alternative Names: 5-Bromo-4-chloro-3-indolyl-ß-D-galactoside (galactopyranoside) in Dimethylformamide. Grades: Molecular Biology Grade. CAS No. 7240-90-6,68-12-2. Pack Sizes: 10ml, 5x10ml. Molecular Formula: C14H15BrClNO6 DMF, Molecular Weight: 408.61. US Biological Life Sciences. |  Worldwide |
| X-Gal (5-Bromo-4-chloro-3-indolyl-b-D-galactoside galactopyranoside, Xgal) | Blue substrate used in the detection of b-galactosidase in bacteria or phage as a selection agent for cloning experiments utilizing the lacZ vector. Colonies expressing b-galactosidase will appear blue in the presence of XGAL. Others will appear white.Gene Cloning:In gene cloning, X-gal is used as a visual indication of whether a cell expresses a functional β-galactosidase enzyme in a technique called blue/white screening. This method of screening is a convenient way of distinguishing a successful cloning product from other unsuccessful ones.The blue/white screening method relies on the principle of α-complementation of the β-galactosidase gene, where a fragment of the lacZ gene (lacZα) in the plasmid can complement another mutant lacZ gene (lacZΔM15) in the cell. Both genes by themselves produce non-functional peptides, however, when expressed together, as when a plasmid containing lacZα is transformed into a lacZΔM15 cells, they form a functional β-galactosidase. The presence of an active β-galactosidase may be detected when cells are grown in plates containing X-gal, the blue-colored product precipitated within cells resulted in the characteristic blue colonies. However, the multiple cloning site, where a gene of interest may be ligated into the plasmid vector, is located within the lacZα gene.... . Group: Biochemicals. Alternative Names: X-Gal, 5-Bromo-4-chloro-3-indolyl-b-D-galactoside (galactopyranoside), BCIG. Grades: Molecular Biology Grade. CAS No. 7240-90-6. Pack Sizes: 100mg, 250mg, 1g, 10g. Molecular Formula: C14H15BrClNO6, Molecular Weight: 408.61. US Biological Life Sciences. | Worldwide |
| X-Gal (5-Bromo-4-chloro-3-indolyl-beta-D-galactopyranoside) | 100mg Pack Size. Group: Stains & Indicators. Formula: C14H15BrClNO6. CAS No. 7240-90-6. Prepack ID 11322533-100mg. Molecular Weight 408.63. See USA prepack pricing. |  |
| X-Gal (5-Bromo-4-chloro-3-indolyl-beta-D-galactopyranoside) | 1g Pack Size. Group: Stains & Indicators. Formula: C14H15BrClNO6. CAS No. 7240-90-6. Prepack ID 11322533-1g. Molecular Weight 408.63. See USA prepack pricing. | |
| X-Gal (5-Bromo-4-chloro-3-indolyl-beta-D-galactopyranoside) | 5g Pack Size. Group: Stains & Indicators. Formula: C14H15BrClNO6. CAS No. 7240-90-6. Prepack ID 11322533-5g. Molecular Weight 408.63. See USA prepack pricing. | |
| x-Galactosaminide,>98% | Heterocyclic Organic Compound. CAS No. 129570-48-1. Purity: 0.96. Catalog: ACM129570481. | |
| X-Gal (aka X-b-D-galactoside) | X-Gal (aka X-b-D-galactoside). CAS No. 7240-90-6. Categories: x-gal. |  Pennsylvania PA |
| x-Gluc | Gluc. CAS No. 18656-96-7. | Pennsylvania PA |
| X-Gluc | X-Gluc. CAS No. 18656-96-7. | Pennsylvania PA |
| X-Gluc cyclohexanamine | X-Gluc cyclohexanamine is a dye reagent for the detection of β-glucuronidase ( GUS ), an enzyme produced by E. coli. X-Gluc cyclohexanamine can be used to detect E. coli contamination in food, water and the urinary tract ( GUS as a specific detection indicator). X-Gluc cyclohexanamine is also widely used in molecular biology experiments to label and detect the expression of target genes (reacts with the GUS gene , appears blue) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 114162-64-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15935B. | |
| X-Gluc Dicyclohexylamine | X-Gluc Dicyclohexylamine is a dye reagent for the detection of β-glucuronidase, an enzyme produced by Escherichia coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract. X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (GUS reporter system) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 18656-96-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-15935. | |
| X-Gluc sodium | X-Gluc sodium is a dye reagent for the detection of β-glucuronidase ( GUS ), an enzyme produced by E. coli. X-Gluc sodium can be used to detect E. coli contamination in food, water and the urinary tract ( GUS as a specific detection indicator). X-Gluc sodium is also widely used in molecular biology experiments to label and detect the expression of target genes (reacts with the GUS gene , appears blue) [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 129541-41-9. Pack Sizes: 50 mg; 100 mg. Product ID: HY-15935C. | |
| Xibornol | Xibornol, a kind of lipophilic drug, could be used in the treatment of infection and inflammation of the throat as spray dosage. Synonyms: 6-Isobornyl-3,4-xylenol; Bactacine. CAS No. 13741-18-9. Molecular formula: C18H26O. Mole weight: 258.41. | |
| Ximelagatran | Ximelagatran (H 376/95) is an orally active thrombin inhibitor that selectively and competitively inhibits both free and clot-bound thrombin. Ximelagatran is an anticoagulant agent with a rapid onset of anticoagulant effect, predictable, dose-dependent pharmcokinetics and pharmacodynamics [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: H 376/95. CAS No. 192939-46-1. Pack Sizes: 10 mM * 1 mL; 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10787. | |
| Ximelagatran | An orally active direct thrombin inhibitor; prodrug of Melagatran. Antithrombotic. Group: Biochemicals. Alternative Names: N- [ (1R) -1-Cyclohexyl-2- [ (2S) -2- [ [ [ [4- [ (hydroxyamino) iminomethyl] phenyl] methyl] amino] carbonyl] -1-azetidinyl] -2-oxoethyl] glycine Ethyl Ester; Exanta; H 376/95. Grades: Highly Purified. CAS No. 192939-46-1. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Ximelagatran | Ximelagatran, an ester prodrug of melagatran, with anticoagulant effect, is the first member of direct thrombin inhibitors that can be taken orally. Uses: An orally active direct thrombin inhibitor; prodrug of melagatran. antithrombotic. Synonyms: H 376-95; H 376/95; H 37695; H-37695; H37695; N- [ (1R) -1-Cyclohexyl-2- [ (2S) -2- [ [ [ [4- [ (hydroxyamino) iminomethyl] phenyl] methyl] amino] carbonyl] -1-azetidinyl] -2-oxoethyl] glycine Ethyl Ester; Exanta; H 376/95. Grades: >98%. CAS No. 192939-46-1. Molecular formula: C24H35N5O5. Mole weight: 473.57. | |
| Ximelagatran Nitrile | Intermediate in the preparation of Ximelagatran. Group: Biochemicals. Alternative Names: N-[ (1R) -2-[ (2S) -2-[[[ (4-Cyanophenyl) methyl]amino]carbonyl]-1-azetidinyl]-1-cyclohexyl-2-oxoethyl]glycine Ethyl Ester. Grades: Highly Purified. CAS No. 260790-61-2. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Xipamide | Xipamide is a diuretic and antihypertensive agent. Group: Biochemicals. Alternative Names: 5-(Aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-benzamide; 4-Chloro-5-sulfamoyl-2',6'-salicyloxylidide; Aquaphor; Chronexan; Diurex; Lumitens. Grades: Highly Purified. CAS No. 14293-44-8. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| Xipamide | Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 14293-44-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-W042301. | |
| Xipamide-d6 | A labeled diuretic and antihypertensive. Group: Biochemicals. Alternative Names: 5-(Aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-benzamide-d6; 4-Chloro-5-sulfamoyl-2',6'-salicyloxylidide-d6; Aquaphor-d6; Chronexan-d6; Diurex-d6; Lumitens-d6. Grades: Highly Purified. CAS No. 1330262-09-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Xipamide impurity 1 | Xipamide impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 14665-31-7. Molecular Formula: C7H4Cl2O5S. Mole Weight: 271.06. Catalog: APB14665317. | |
| Xipamide impurity 2 | Xipamide impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1330262-09-3. Molecular Formula: C15H9D6ClN2O4S. Mole Weight: 360.84. Catalog: APB1330262093. | |
| XIRAN Heatboosters | XIRAN Heatboosters. Group: Polymers. | |
| XK-101-2 | XK-101-2 is a nucleoside antibiotic isolated from Micromonospora chalcea subsp. It exhibits activity against Mycobacterium phlei and gram-positive bacteria. Molecular formula: C11H13N3O5. Mole weight: 267.24. | |
| XK469 | XK489 is a synthetic quinoxaline phenoxypropionic acid derivative with proapoptotic and antiproliferative activities. R(+)XK469 selectively inhibits topoisomerase II-beta, blocks activation of MEK/MAPK signaling kinases, stimulates caspases, and upregulates p53-dependent proteins, including cyclins A and B1, thereby arresting cancer cells in the G2/M phase of the cell cycle. Both R(+) and S(-) isomers of this agent are cytotoxic, although the R-isomer is more potent. Synonyms: XK 469; XK-469; NSC-698216; 2-(4-((7-Chloro-2-quinoxalinyl)oxy)phenoxy)propanoic acid. CAS No. 157435-10-4. Molecular formula: C17H13ClN2O4. Mole weight: 344.75. | |
| XK-90 | XK-90 is produced by Streptomyces sp. It is active against Gram-positive and Gram-negative bacteria. Synonyms: Antibiotic XK 90; 5-(2-Acetylhydrazino)salicylaldehyde. CAS No. 61172-42-7. Molecular formula: C9H10N2O3. Mole weight: 194.19. | |
| XL019 | XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, displaying 100-fold selectivity over JAK1. XL019 inhibits proliferation and induce apoptosis in cells carrying the JAK2V617F mutation. Synonyms: (S)-N-(4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)phenyl)pyrrolidine-2-carboxamide; XL-019. Grades: >98%. CAS No. 945755-56-6. Molecular formula: C25H28N6O2. Mole weight: 444.539. | |
| XL147 | Pilaralisib is a Class 1 phosphatidylinositol 3 kinase (PI3K) family inhibitor. It is an orally bioavailable small molecule, targeting the class I PI3K family of lipid kinases. It is a pyrimidine derivatives compound discovered by Exelixis Inc. It has potential antineoplastic activity. It binds to class 1 PI3Ks in an ATP-competitive manner by inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and inhibiting the activation of the PI3K signaling pathway. Uses: Pilaralisib has potential antineoplastic activity. Synonyms: XL147-II; XL147 II; XL147II; XL147 derivative II; XL147derivativeII; XL147-derivative-II; N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methylbenzenesulfonamide;SAR245408;N-[3-(Benzo[c][1,2,5]thiadiazol-5-ylaMino)quinoxalin-2-yl]-4-MethylbenzenesulfonaMide;PI3K inhibitorX. Grades: >99%. CAS No. 956958-53-5. Molecular formula: C21H16N6O2S2. Mole weight: 448.52. | |
| Xl-184 | Heterocyclic Organic Compound. CAS No. 1021950-26-4. Molecular formula: C31H31FN6O5. Catalog: ACM1021950264. | |
| XL 184 | XL 184. Group: Biochemicals. Grades: Purified. CAS No. 849217-68-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| XL228 | XL228 is a protein kinase inhibitor targeting IGF1R, the Aurora kinases, FGFR1-3, ABL and SRC family kinases. Synonyms: XL-228; XL228; XL 228. Grades: 0.98. CAS No. 898280-07-4. Molecular formula: C22H31N9O. Mole weight: 437.54. | |
| XL388 | XL388 is a Novel Class of Highly Potent, Selective, ATP-Competitive, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin (mTOR). XL388 inhibited cellular phosphorylation of mTOR complex 1 (p-p70S6K, pS6, and p-4E-BP1) and mTOR complex 2 (pAKT (S473)) substrates. XL388 displayed good pharmacokinetics and oral exposure in multiple species with moderate bioavailability. Synonyms: XL388; XL-388; XL 388. Grades: 0.98. CAS No. 1251156-08-7. Molecular formula: C23H22FN3O4S. Mole weight: 455.504. | |
| XL 388 | XL 388. Group: Biochemicals. Grades: Purified. CAS No. 1251156-08-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| XL413 | XL413 is a potent and selective Cdc7 inhibitor with an IC50 of 3.7 nM, with a 60-fold selectivity against CK2,10-fold selectivity against PIM, and 300-fold selectivity against a panel of over 100 protein kinases. Synonyms: BMS-863233; BMS863233; BMS 863233; XL-413; XL413; XL 413. Grades: >98%. CAS No. 1169558-38-6. Molecular formula: C14H12ClN3O2. Mole weight: 289.72. | |
| XL 413 hydrochloride | XL 413 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1169562-71-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| XL413 hydrochloride | XL413 is a potent and selective inhibitor of Cdc7 with IC50 value of 3.4 nM. It exhibits >60, >10, and >300-fold selectivity for Cdc7 over CK2, PIM1, and a panel of over 100 protein kinases, respectively. Synonyms: 8-Chloro-2-[(2S)-pyrrolidin-2-yl]-4aH-[1]benzofuro[3,2-d]pyrimidin-4-one hydrochloride. Grades: ≥98%. CAS No. 2062200-97-7. Molecular formula: C14H12ClN3O2·HCl. Mole weight: 326.18. | |
| XL-418 | XL-418 is a 70 kDa ribosomal protein S6 kinase and Proto oncogene protein c-akt inhibitor. It can inhibit the activities of PKB and p70S6K, both acting downstream of phosphoinosotide-3 kinase (PI3K). But in Dec 2007, Phase-I for Solid tumours in USA was discontinued. Uses: Solid tumours. Synonyms: XL418; XL-418; X 418; 1-(3-(4-(3-bromo-1H-pyrazolo[3,4-d]pyrimidin-4-yl)piperazin-1-yl)-4-methyl-5-((2-(pyrrolidin-1-yl)ethyl)amino)phenyl)-4,4,4-trifluorobutan-1-one. Grades: 98%. CAS No. 871343-09-8. Molecular formula: C26H32BrF3N8O. Mole weight: 609.49. | |
| XL44 | XL44, an hRpn13 binder, induces hRpn13-dependent apoptosis and also restricts cell viability by a PCLAF-dependent mechanism. XL44 induces ubiquitin-dependent loss of hRpn13 Pru and ubiquitin-independent loss of select KEN box containing proteins [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2637949-91-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162393. | |
| XL-647 | XL647 is an orally bioavailable small-molecule receptor tyrosine kinase inhibitor with potential antineoplastic activity. It inhibits EGFR, HER2, VEGFR and EphB4 kinase. Synonyms: XL-647; XL 647; XL647; EXEL-7647; EXEL 7647; EXEL7647; KD-019; KD 019; KD019. Grades: >98%. CAS No. 781613-23-8. Molecular formula: C24H25Cl2FN4O2. Mole weight: 491.39. | |
| XL 765 | XL 765 is a PI3K inhibitor used for the treatment of cancers. It also suppresses DNA-PK and mTOR. Synonyms: XL765-II; XL765 II; XL765II; XL 765-II; XL-765-II; SAR 245409; SAR245409; SAR-245409; N-[4-[[[3-[(3,5-Dimethoxyphenyl)amino]-2-quinoxalinyl]amino]sulfonyl]phenyl]-3-methoxy-4-methylbenzamide; N-(4-(N-(3-((3,5-Dimethoxyphenyl)amino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide. CAS No. 1349796-36-6. Molecular formula: C31H29N5O6S. Mole weight: 599.662. | |
| XL888 | XL888 is an ATP-competitive inhibitor of Hsp90. Through this action, specific client proteins are degraded, leading to cell cycle arrest or apoptosis. XL888 is orally bioavailable and displays efficacy in tumor regression in gastric carcinoma and melanoma xenografts in mice. Synonyms: XL888; XL 888; XL-888. Grades: >98%. CAS No. 1149705-71-4. Molecular formula: C29H37N5O3. Mole weight: 503.64. | |
| XL999 | XL999, a Spectrum Selective Kinase Inhibitor(TM) (SSKIs), is a potent inhibitor of key RTKs implicated in the development and maintenance of tumor vasculature and in the proliferation of some tumor cells. It inhibits the FGFR, VEGFR and PDGFR RTKs and exhibited excellent activity in target-specific cellular functional assays. In addition, XL999 is a potent inhibitor of FLT3, an important driver of leukemia cell proliferation in some patients with acute myelogenous leukemia (AML). In several preclinical models of human tumors, including breast, lung, colon and prostate cancer, XL999 demonstrated potent inhibition of tumor growth, and also caused regression of large well-established tumors. Phase I studies of XL999 established a maximum tolerated dose and showed evidence of tumor responses. Synonyms: XL999; XL 999; XL-999. CAS No. 705946-27-6. Molecular formula: C26H28FN5O. Mole weight: 445.532. | |
| XL 999 | XL999 is a multi-target tyrosine kinase inhibitor. XL999 has IC 50 values for KDR , Flt-1 , FGFR1 and PDGFRα of 4 nM, 20 nM, 4 nM and 2 nM, respectively. XL999 can be used in the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tyrosine kinase-IN-1. CAS No. 705946-27-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100315. | |
| XL PI3K/mTOR inhibitor | An orally bioactive PI3K/mTOR tyrosine kinase inhibitor. Synonyms: N-(3-(N-(3-((3,5-dimethoxyphenyl)amino)quinoxalin-2-yl)sulfamoyl)phenyl)-3-methoxy-4-methylbenzamide. Grades: 99%. CAS No. 934529-30-3. Molecular formula: C31H29N5O6S. Mole weight: 599.66. | |
| XLR11-d4 | XLR11-d4. Group: Biochemicals. Alternative Names: [1- (5-Fluoropentyl) -1H-indol-3-yl] (2, 2, 3, 3-tetramethylcyclopropyl ) methanone-d4. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C21H24D4FNO, Molecular Weight: 333.48. US Biological Life Sciences. | Worldwide |
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