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| Product | Description | |
|---|---|---|
| Yeast extract | Yeast extract is a concentrate of the soluble part of yeast, especially Saccharomyces cerevisiae. The main nutritional components of yeast extract include partly hydrolyzed protein with 35-40% of free amino acid, and it also contain B vitamins and some trace elements. Yeast extract can be used as nutrients for bacterial culture media [1]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 8013-1-2. Pack Sizes: 50 g; 100 g. Product ID: HY-153126. |  |
| Yeast extract | 100g Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: N/A. CAS No. 8013-1-2. Prepack ID 35752308-100g. See USA prepack pricing. |  |
| Yeast Extract | Yeast Extract is a food flavoring. It can be used in culture medium. Synonyms: Yeast, ext.; Yeast powder; Extract of Yeast; Yeast Extract Powder. CAS No. 8013-1-2. |  |
| Yeast Extract Polar | Yeast Extract Polar. Group: Others. Stability: 3 Months. Storage: -20°C. Avanti Polar Lipids; lipid products; natural lipids; natural; synthetic lipid; synthetic; modified lipids; headgroup modified lipids; fatty acid modified lipids; singnal transduction; cell pathways; Yeast Extract Polar; Yeast Polar Lipid Extract (S. cerevisiae). Cat No: NSMZ-048. |  |
| Yeast Extract Total | Yeast Extract Total. Group: Others. Stability: 3 Months. Storage: -20°C. Avanti Polar Lipids; lipid products; natural lipids; natural; synthetic lipid; synthetic; modified lipids; headgroup modified lipids; fatty acid modified lipids; singnal transduction; cell pathways; Yeast Extract Total; Yeast Total Lipid Extract (S. cerevisiae). Cat No: NSMZ-047. | |
| Yeast, Powder, Activated, Laboratory Grade, 100 g | Storage Code: Green; general chemical storage. Grades: chem-grade laboratory. Product ID: 898890. -- SOLD FOR EDUCATIONAL USE ONLY -- |  |
| Yeast Protein Extract | Yeast Protein Extract. Uses: For analytical and research use. Group: Building blocks. Alternative Names: TP. Catalog: APS013955. Shipping: Room Temperature. |  |
| yeast ribonuclease | Similar enzyme: RNase U4. Group: Enzymes. Enzyme Commission Number: EC 3.1.14.1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3541; yeast ribonuclease; EC 3.1.14.1. Cat No: EXWM-3541. | |
| Yeast S | A dried Aspergillus oryzae fermentation extract that is an ideal nutrient support system for yeast during the fermentation process. It contains protein, free-form amino acids, minerals, enzymes, vitamins, fiber and other nutrients. Group: Enzymes. Synonyms: Yeast S; Yeast; BRE-1622. Yeast S. Appearance: powder or liquid. Yeast S; Yeast; BRE-1622. Pack: 25kg/paper barrel (powder form), 30kg/polyster barrel (liquid form) or subject to client requirement. Cat No: BRE-1622. | |
| Yeasts. Riched selenium | Yeasts. Riched selenium. Product ID: CDF4-0217. Molecular formula: NA. Category: Nutrient supplements. Product Keywords: Food Ingredients; Nutrients; CDF4-0217; Yeasts. Riched selenium; Nutrient supplements. Applications: Used as selenium enhancer in dairy products, rice products, biscuits and beverages. |  |
| Yellow Dextrin Nanopowder | Yellow Dextrin Nanopowder. Group: Metal nano dispersion. CAS No. 9004-53-9. 99.9%. |  |
| Yellow Dock Extract | Extract obtained from Rumex Crispus (Yellow Dock) roots. Contains 20% extract dissolved in water and glycerin. Has soothing, calming and anti-irritant properties. Uses: Lotions, creams, hair care and bath products. Group: Skin actives. CAS No. 7732-18-5 / 56-81-5 / 90106-41-5 / 122-99-6. Appearance: Light to medium amber liquid, characteristic odor. Catalog: CI-SC-0918. |  |
| Yellow iron oxide | Yellow iron oxide is commonly used in painting, concrete and scagliola. Synonyms: C.I. Pigment Yellow 42; Ariabel Yellow 300407; C.I. 77492; Cameleon Yellow; Disperse HG 457; Ecosperse Oxide Yellow RA 100CN; Ferric oxide, yellow; Goethite yellow; Iron hydroxide oxide yellow; Iron Oxide Orange Transparent 188VN; Iron oxide yellow; Iron Yellow; NX 512 Yellow; Pigment Yellow 42; Sicopharm Yellow; Synthetic yellow iron oxide pigment; Tarox Yellow Lemon; Xeracolor Yellow Oxide; Xeracolour Yellow Oxide; Zh 1 (pigment). CAS No. 51274-00-1. | |
| Yellow Iron Oxide USP | Yellow Iron Oxide USP. CAS No. 51274-00-1. |  |
| Yerba Mate Extract, USDA Certified Organic | Organic Yerba mate extract dissolved in water and an organic rice solution. Preserved with Leuconostoc Ferment Filtrate. Uses: Anti-puffiness eye creams, anti-aging & anti-wrinkle creams, lotions, serums. Group: Skin actives. CAS No. 68553-81-1 / 7732-18-5 / 73296-98-7 / 68333-16-4 / 9054-89-1 / 9003-99-0. Catalog: CI-SC-0738. | |
| YF-0200R-A | YF-0200R-A is a pepstatin A-sensitive Candida albicans aspartyl protease inhibitor produced by Streptomyces sp. YF-0200R. It inhibits aspartyl protease from Candida albicans with IC50 value of 6.5 x 10(-4) M. Synonyms: YF 0200R-A; YF 0200R A; 8,12-Dihydroxy-2,4-dodecadienoic acid. CAS No. 156368-99-9. Molecular formula: C12H20O4. Mole weight: 228.28. | |
| YF-0200R-B | YF-0200R-B is a pepstatin A-sensitive Candida albicans aspartyl protease inhibitor produced by Streptomyces sp. YF-0200R. It inhibits aspartyl protease from Candida albicans with IC50 value of 6.2 x 10(-4) M. Synonyms: YF 0200R-B; YF 0200R B; 8,10,12-trihydroxydodeca-2,4-dienoic acid. CAS No. 156369-00-5. Molecular formula: C12H20O5. Mole weight: 244.28. | |
| YF-044P-D | YF-044P-D is a Candida albicans aspartyl protease inhibitor produced by Streptomyces sp. SF-044P. It inhibits Candida albicans aspartyl protease with IC50 of 6.4 X 10(-7) mol/L. Synonyms: YF 044P-D; YF-044-P-D. CAS No. 158335-52-5. Molecular formula: C43H57N5O9. Mole weight: 787.9. | |
| YF-18 | YF-18 is a matrine derivative that has an inhibitory effect on lung cancer cells. Studies indicated that YF-18 induced G2/M cell cycle arrest and inhibited migration of lung cancer cells in a dose-dependent manner. In addition, it suppressed cell proliferation and migration through down-regulating Skp2 and up-regulating its substrates, p27 and E-cadherin. Uses: Anti-lung cancer. Synonyms: YF 18; YF18. | |
| YF-2 | YF-2 is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC 50 s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1311423-89-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16531. | |
| YF-2 hydrochloride | YF-2 hydrochloride is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC 50 s of 2.75 μM, 29.04 μM and 49.31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimer's disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1312005-62-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-16531A. | |
| YFGAP | YFGAP is an antibacterial peptide isolated from Yellowfin tuna (Thunnus albacares). It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: YFGAP-OH; Val-Lys-Val-Gly-Ile-Asn-Gly-Phe-Gly-Arg-Ile-Gly-Arg-Leu-Val-Thr-Arg-Ala-Ala-Phe-His-Gly-Lys-Lys-Val-Glu-Val-Val-Ala-Ile-Asn-Asp. Molecular formula: C154H258N48O40. Mole weight: 3422.04. | |
| YH239-EE | YH239-EE is an ethyl ester of YH239, which acts as a MDM2-p53 inhibitor. YH239-EE induces apoptosis in four AML cells. It promotes survival of aged muscle stem cells (muSCs). Synonyms: Ethyl 3-(2-(tert-butylamino)-1-(N-(4-chlorobenzyl)formamido)-2-oxoethyl)-6-chloro-1H-indole-2-carboxylate. Grades: >98%. CAS No. 1364488-67-4. Molecular formula: C25H27Cl2N3O4. Mole weight: 504.41. | |
| YH-306 | YH-306 is a candidate drug in preventing growth and metastasis of CRC by modulating FAK signalling pathway. Synonyms: YH 306; YH306. CAS No. 1373764-75-0. Molecular formula: C19H18N2O2. Mole weight: 306.36. | |
| YHO-13177 | YHO-13177 is a potent and specific inhibitor of BCRP. It potentiated the cytotoxicity of SN-38 in cancer cells and had no effect on P-glycoprotein-mediated paclitaxel resistance in MDR1-transduced human leukemia K562 cells. Synonyms: YHO-13177; YHO 13177; YHO13177. Grades: >98%. CAS No. 912287-56-0. Molecular formula: C20H22N2O3S. Mole weight: 370.47. | |
| YHO-13351 | YHO-13351 is the water-soluble prodrug of YHO-13177, which is a potent and specific inhibitor of BCRP. Synonyms: YHO-13351; YHO 13351; YHO13351. Grades: >98%. CAS No. 1346753-00-1. Molecular formula: C27H37N3O7S2. Mole weight: 579.73. | |
| YHO-13351 free base | YHO-13351 free base is a potent and specific inhibitor of BCRP, which is the water-soluble prodrug of YHO-13177. It potentiates the cytotoxicity of SN-38, mitoxantrone, and topotecan in both BCRP-transduced human colon cancer HCT116 cells and SN-38-resistant human lung cancer A549 cells, but had little effect in the parental cells in vitro. It also potentiates the cytotoxicity of SN-38 in human lung cancer NCI-H23 and NCI-H460, myeloma RPMI-8226 and pancreatic cancer AsPC-1 cell. It increases the intracellular accumulation of Hoechst 33342. It is rapidly converted into YHO-13177 after its oral or intravenous administration in mice. Uses: Yho-13351 free base could potentiate the cytotoxicity of sn-38, mitoxantrone and topotecan. Synonyms: YHO13351 free base; YHO 13351 free base; YHO-13351 free base. Grades: >98%. CAS No. 912288-64-3. Molecular formula: C26H33N3O4S. Mole weight: 483.62. | |
| YIGSR | YIGSR is a peptide that can inhibit the tumour growth and metastasis of leukaemic cells [1]. YIGSR blocks the cellular binding to laminin I via a 67-kDa laminin-binding protein, and inhibits shear-induced increase in eNOS expression of laminin cells [2]. Uses: Scientific research. Group: Peptides. Alternative Names: Laminin Fragment 929-933. CAS No. 110590-64-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0132. | |
| YIL781 | YIL781 is a potent and orally active ghrelin receptor (GHSR) antagonist. YIL781 produces a greater improvement in glucose homeostasis in rats. YIL781 inhibits the calcium response induced by ghrelin with pIC 50 values of 7.90 and 8.27, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 875258-85-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-13964. | |
| YIL 781 | YIL 781 is a ghrelin receptor antagonist (GHS-R1a) (Ki = 17 nM) with no significant affinity for the motilin receptor (Ki = 6 μM). YIL 781 inhibits ghrelin to reduce insulin secretion both in vivo and in vitro. YIL 781 may be beneficial for the treatment of obesity and diabetes. Uses: Potential treatment of obesity and diabetes. Synonyms: YIL 781; YIL781; YIL-781; 6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone; KB-276128; KB 276128; KB276128. Grades: ≥98% by HPLC. CAS No. 875258-85-8. Molecular formula: C24H28FN3O2. Mole weight: 409.51. | |
| YIL781 hydrochloride | YIL781 hydrochloride is a potent and orally active ghrelin receptor (GHSR) antagonist. YIL781 hydrochloride produces a greater improvement in glucose homeostasis in rats. YIL781 hydrochloride inhibits the calcium response induced by ghrelin with pIC 50 values of 7.90 and 8.27, respectively [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1640226-17-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-13964A. | |
| YIL 781, Hydrochloride Salt | Ghrelin receptor antagonist (GHS-R1a) (Ki = 17nM). Displays no significant affinity for the motilin receptor (Ki = 6uM). Blocks the effects of ghrelin on insulin secretion both in vivo and in vitro. Improves glucose homeostasis in vivo. Group: Biochemicals. Alternative Names: 6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone. Grades: Highly Purified. CAS No. 875258-85-8. Pack Sizes: 5mg. Molecular Formula: C??H??FN?O?.HCl, Molecular Weight: 445.96. US Biological Life Sciences. |  Worldwide |
| YJC-10592 | YJC-10592 is a CC chemokine receptor 2 (CCR2) antagonist (IC50 value 1.12 μM). Synonyms: YJC-10592; YJC 10592; YJC10592. Grades: 98%. CAS No. 1226894-87-6. Molecular formula: C27H31ClF3N5O3. Mole weight: 566.01. | |
| YK11 | YK11 is a partial agonist of androgen receptor , with osteogenic activity. Uses: Scientific research. Group: Signaling pathways. CAS No. 1370003-76-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107480. | |
| YK-2168 | YK-2168 is a differentiated selective inhibitor of CDK9 [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2571068-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162919. | |
| YK 3-237 | YK 3-237 is a sirtuin-1 (SIRT1) activator. YK 3-237 inhibits proliferation of breast cancer cell lines expressing mutant p53, and induces G2/M cell cycle arrest in triple negative breast cancer cells (TNBCs) in vitro. Synonyms: B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid. Grades: ≥98% by HPLC. CAS No. 1215281-19-8. Molecular formula: C19H21BO7. Mole weight: 372.18. | |
| YK-4-279 | YK-4-279 blocks RNA Helicase A (RHA) binding with EWS-FLI1 (oncogenic protein). YK-4-279 induces apoptosis and shows anti-proliferation activities towards various cancer cells. YK-4-279 has a chiral center and it can be separated into two enantiomers. YK-4-279 can be used for the research of cancer [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1037184-44-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14507. | |
| YK-4-279 | YK-4-279 is a potent inhibitor of EWS-FLI1 binding to RNA helicase A (RHA).YK-4-279 eliminates cyclin D levels by blocking the interaction of EWS-FLI1 with RHA in EWS-FLI1-containing TC32 cells. Synonyms: YK-4-279; YK4-279; YK 4-279; YK-4279; YK4279; YK 4279. Grades: >98%. CAS No. 1037184-44-3. Molecular formula: C17H13Cl2NO4. Mole weight: 366.20. | |
| YKL-05-099 | YKL-05-099 has slightly less potent SIK2-inhibitory (IC50 = 40 ± 25 nM) and IL-10-enhancing activities (EC50 = 460 ± 110 nM), but is non-toxic at concentrations ≤ 10 μM and stable in mouse liver microsomes for > 2 hours. Synonyms: YKL 05 099; YKL05099. CAS No. 1936529-65-5. Molecular formula: C32H34ClN7O3. Mole weight: 600.11. | |
| YKL-05-099 | YKL-05-099 is a selective inhibitor of Salt-Inducible Kinase (SIK). Group: Inhibitors. Alternative Names: YKL-05-099; YKL 05 099; YKL05099. CAS No. 1936529-65-5. Molecular formula: C32H34ClN7O3. Mole weight: 600.12. Appearance: Solid powder. Purity: >98%. IUPACName: 3-(2-Chloro-6-methylphenyl)-7-((2-methoxy-4-(1-methylpiperidin-4-yl)phenyl)amino)-1-(5-methoxypyridin-2-yl)-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one. Canonical SMILES: O=C1N (C2=NC=C (OC)C=C2)C3=NC (NC4=CC=C (C5CCN (C)CC5)C=C4OC)=NC=C3CN1C6=C (C)C=CC=C6Cl. Catalog: ACM1936529655. | |
| YKL-06-061 | YKL-06-061 is a small molecule serine/threonine-protein kinase SIK1 inhibitor (Ki = 6.56 nM) that is hopefully developed to be a dermatologic drug impacting UV protection and skin cancer risk. It causes a dose-dependent increase in microphthalmia-associated transcription factor (MITF) mRNA expression during 3-hour function in normal human melanocytes, UACC62 human melanoma cells, and UACC257 human melanoma cells. Uses: A potential dermatologic drug. Synonyms: YKL06-061; YKL 06-061; YKL-06061. CAS No. 2172617-15-9. Molecular formula: C30H37N7O2. Mole weight: 527.67. | |
| YKL-06-062 | YKL-06-062 is a small molecule serine/threonine-protein kinase SIK1 inhibitor (Ki = 2.12 nM) that is hopefully developed to be a dermatologic drug impacting UV protection and skin cancer risk. It causes a dose-dependent increase in microphthalmia-associated transcription factor (MITF) mRNA expression during 3-hour function in normal human melanocytes, UACC62 human melanoma cells, and UACC257 human melanoma cells. Uses: A potential dermatologic drug. Synonyms: YKL 06 062. CAS No. 2172617-16-0. Molecular formula: C31H39N7O. Mole weight: 525.69. | |
| YL-109 | Mice treated with vehicle showed significantly enlarged tumors, whereas mice treated with YL-109 showed attenuated tumor growth using MCF-7 cells. Interestingly, YL-109 also suppressed tumor growth in mice injected with MDA-MB-231 cells. Compared with the vehicle control, YL-109 significantly reduced lung metastasis. Synonyms: YL-109; YP109; YP 109. Grades: >98%. CAS No. 36341-25-0. Molecular formula: C14H11NO2S. Mole weight: 257.31. | |
| YL-704A1 | YL-704A1 is a main component of YL-704, a macrolide antibiotic complex isolated from Streptomyces platensis subsp. malvinus. It is active against gram-positive bacteria. Synonyms: Yl 704A1; Yl 704 A1. CAS No. 40615-47-2. Molecular formula: C43H71NO15. Mole weight: 842. | |
| Ylangenol | Ylangenol is extracted from Laggera pterodonta. CAS No. 41610-69-9. Molecular formula: C15H24O. Mole weight: 220.356. | |
| Ylang Ylang Oil | 100g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: N/A. CAS No. 8006-81-3. Prepack ID 89992786-100g. See USA prepack pricing. | |
| YLF-466D | YLF466D activated recombinant human α1β1γ1, α2β1γ1 and rat liver AMPK. It also activated AMPK α-subunit truncations containing an autoinhibitory domain(AID) and exhibited additivity with AMP and A-769662. Molecular docking of YLF466D with the S pombe AMPKa (25-351) suggests it may bind in the cleft between the kinase domain and the AID antagonizing the auto-inhibition distinct from AMP and A-769662. Incubation of YLF466D in Hela cells activated cellular AMPK without detectable changes in AMP:ATP ratio, proving AMPK was allosterically activated by YLF466D. YLF466D activated cellular AMPK in both L6 myotubes and HepG2 cells with evoking intracellular AMP:ATP ratio accompanied by depolarizing mitochondria membrane potential, but has no effect on the dephosphorylation of PP2Cα on AMPK. Thus, YLF466D activated cellular AMPK through dual mechanisms. Functional studies shown YLF466D stimulated glucose uptake in L6 myotubes, decreased glucose output and lipid content in hepatocyte. Acute and chronic treatment of YLF466D on diabetic db/db mice and diet induced obese mice improved metabolic parameters. Synonyms: C24; YLF 466D; YLF466D. Grades: >98%. CAS No. 1273323-67-3. Molecular formula: C29H20ClNO3. Mole weight: 465.93. | |
| YM 022 | YM 022. Group: Biochemicals. Grades: Highly Purified. CAS No. 145084-28-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| YM 022 | YM 022 is a highly potent and selective non-peptide CCK2 silent antagonist (Ki = 68 pM and 63 nM at CCK2 and CCK1 receptors, respectively). YM 022 can inhibit gastrin-induced gastric acid secretion and histidine decarboxylase activation in vivo with a long duration of action. Synonyms: YM022; YM-022; (R)-N-[2,3-Dihydro-1-[2-(2-methylphenyl)-2-oxoethyl]-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(3-methylphenyl)-urea; N-[(3R)-2,3-Dihydro-1-[2-(2-methylphenyl)-2-oxoethyl]-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-N'-(3-methylphenyl)-urea; 3-(3-methylphenyl)-1-[(3R)-1-[2-(2-methylphenyl)-2-oxoethyl]-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]urea. Grades: ≥99% by HPLC. CAS No. 145084-28-2. Molecular formula: C32H28N4O3. Mole weight: 516.59. | |
| YM155 | YM155. Group: Biochemicals. Alternative Names: 4,9-Dihydro-1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(2-pyrazinylmethyl)-1H-naphth[2,3-d]imidazolium Bromide; Sepantronium bromide; YM 155. Grades: Highly Purified. CAS No. 781661-94-7. Pack Sizes: 10mg. Molecular Formula: C20H19BrN4O3, Molecular Weight: 443.29. US Biological Life Sciences. | Worldwide |
| YM-155 hydrochloride | YM155 is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM. Synonyms: YM155 hydrochloride; YM 155 hydrochloride. Grades: >98%. CAS No. 355406-09-6. Molecular formula: C20H19ClN4O3. Mole weight: 398.84. | |
| YM-170320 | YM-170320 is a lipopeptide antibiotic produced by an unidentified fungal strain YL-03706F. It was shown to induce morphological change of colonies in a mutant of Candida tropicalis pK233. It is a novel ergosterol biosynthesis inhibitor. Synonyms: 5-Amino-4-hydroxy-5-oxo-2-[[3-[[2-[(2,6,10,14-tetramethyl-3-hydroxy-1,7-dioxo-8,10-icosadiene-1-yl)amino]propenoyl]amino]-2-methylpropanoyl]amino]pentanoic acid methyl ester. Molecular formula: C37H62N4O9. Mole weight: 706.91. | |
| YM-181741 | YM-181741 is a novel benz[a]anthraquinone antibiotic isolated from the culture broth of actinomycete strain Q57219. It showed selective anti-Helicobacterpylori activity with a MIC value of 0.2 microg/ml. Molecular formula: C19H14O5. Mole weight: 322.3. | |
| YM-201636 | YM201636 is an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, can halt glucose entry by insulin in adipocytes. YM201636 almost completely inhibited basal and insulin-activated 2-deoxyglucose uptake at doses as low as 160 nM, with IC(50)=54+/-4 nM for the net insulin response. Insulin-induced GLUT4 translocation was partially inhibited at substantially higher doses, comparable to those required for inhibition of insulin-induced phosphorylation of Akt/PKB. In addition to PIKfyve, YM201636 also completely inhibited insulin-dependent activation of class IA PI 3-kinase. Synonyms: YM 201636; YM201636. Grades: >98%. CAS No. 371942-69-7. Molecular formula: C25H21N7O3. Mole weight: 467.48. | |
| YM201636, Phosphoinositide Kinase Inhibitor (6-Amino-N- (3- (4- (4-morpholinyl) pyrido[3?2?: 4, 5]furo[3, 2-d]pyrimidin-2-yl) phenyl) -3-pyridine carboxamide) | Cell-permeable. YM-201636 is a selective inhibitor of phosphoinositide kinase (PIK) PIKfyve (IC503nM). It inhibits p110a at higher concentration (IC50=3uM). It reversibly impairs endosomal trafficking in NIH3T3 cells, mimicking the effect produced by depleting PIKfyve with siRNA. YM-201636 also blocks retroviral exit by budding from cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 371942-69-7. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| YM 202074 | High affinity, selective metabotropic glutamate receptor type 1 (mGlu1) antagonist. Binds an allosteric site of the rat mGlu1 receptor with a Ki of 4.8 nM. Inhibits mGlu1-mediated inositol phosphates production (IC50 = 8.6 nM in rat cerebellar granule cells). Neuroprotective in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 299900-84-8. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| YM 202074 | YM 202074 is a high affinity and selective metabotropic glutamate receptor type 1 (mGlu1) antagonist. YM 202074 binds to an allosteric site of the rat mGlu1 receptor (Ki = 4.8 nM) and inhibits mGlu1-mediated inositol phosphates production (IC50 = 8.6 nM in rat cerebellar granule cells). Synonyms: YM 202074; YM202074; YM-202074; N-Cyclohexyl-6-[[N-(2-methoxyethyl)-N-methylamino]methyl]-N-methylthiazolo[3,2-a]benzoimidazole-2-carboxamide sesquifumarate. Grades: ≥99% by HPLC. CAS No. 299900-84-8. Molecular formula: C22H30N4O2S.3/2C4H4O4. Mole weight: 588.67. | |
| YM-202204 | YM-202204 is an antifungal antibiotic isolated from the culture broth of marine fungus Phoma sp. Q60596. It exhibited potent antifungal activities against Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus, and also inhibited glycosyl-phosphatidyl-inositol (GPI)-anchoring in yeast cells. Synonyms: 6'-(2,8-Dihydroxy-1,5,7,9,13,15,17-heptamethyl-nonadeca-3,5,11,13-tetraenyl)-3,4,4'-trihydroxy-6-hydroxymethyl-3,4,5,6-tetrahydro-2H-[2,3']bipyranyl-2'-one. Molecular formula: C37H58O9. Mole weight: 646.8. | |
| YM 230888 | YM 230888 is a selective mGlu1 antagonist (Ki = 13 nM) that inhibits mGlu1-mediated inositol phosphate production in rat cerebellar granule cells (IC50 = 13 nM). YM 230888 displays antinociceptive and analgesic effects in vitro, and exhibits no significant sedative effect on locomotor activity. Synonyms: YM 230888; YM230888; YM-230888; 4-(Cycloheptylamino)-N-[[(2R)-tetrahydro-2-furanyl]methyl]-thieno[2,3-d]pyrimidine-6-methanamine; N-cycloheptyl-6-[[[(2R)-oxolan-2-yl]methylamino]methyl]thieno[2,3-d]pyrimidin-4-amine. Grades: ≥99% by HPLC. CAS No. 446257-23-4. Molecular formula: C19H28N4OS. Mole weight: 360.52. | |
| YM-24074 | YM-24074 is a type I collagenase inhibitor isolated from Streptomyces sp. YL-01869P. Synonyms: YM 24074. Molecular formula: C21H38N4O5. Mole weight: 426.6. | |
| YM 244769 | YM 244769. Group: Biochemicals. Grades: Highly Purified. CAS No. 837424-39-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| YM 2447690 | YM 2447690. Group: Biochemicals. Alternative Names: N-[ (3-Aminophenyl) methyl]-6-[4-[ (3-fluorophenyl) methoxy]phenoxy]-3-pyridinecarboxamide Hydrochloride. Grades: Highly Purified. CAS No. 837424-39-2. Pack Sizes: 10mg. Molecular Formula: C26H23ClFN3O3, Molecular Weight: 478.94. US Biological Life Sciences. | Worldwide |
| YM-244769 dihydrochloride | YM-244769 dihydrochloride is a potent Na+/Ca2+ exchange inhibitor. It preferentially inhibits NCX3 (IC50 = 18 nM). CAS No. 1780390-65-9. Molecular formula: C26H24Cl2FN3O3. Mole weight: 516.39. | |
| YM-254890 | YM-254890 is a selective Gαq/11 protein inhibitor isolated from Chromobacterium sp. QS3666. YM-254890 (1, 3, and 10 μg/kg) reduces platelet thrombus formation in a cynomolgus monkey model of femoral artery thrombosis. CAS No. 568580-02-9. Molecular formula: C46H69N7O15. Mole weight: 960.1. | |
| YM-266183 | YM-266183 is a thiopeptide antibiotic produced by Bacillus cereus QN 03323. It exhibits antibacterial against staphylococci and enterococci, including MRSA and VRE. Synonyms: 13',19'-Didehydro-17',19'-dideoxy-28,44-dihydro-41,44-dihydroxy-17'-oxomicrococcin P. Molecular formula: C48H47N13O10S6. Mole weight: 1158.35. | |
| YM-266184 | YM-266184 is a thiopeptide antibiotic produced by Bacillus cereus QN 03323. It exhibits antibacterial against staphylococci and enterococci, including MRSA and VRE. Synonyms: 13',19'-Didehydro-17',19'-dideoxy-28,44-dihydro-41-hydroxy-44-methoxy-17'-oxomicrococcin P. Molecular formula: C49H49N13O10S6. Mole weight: 1172.37. | |
| YM 26734 | YM 26734 is a competitive inhibitor of secretory phospholipase A2 (sPLA2) with a broad inhibitory profile to several sPLA2s (IC50 = 0.2, 1, 1, 1 and 3 μM for sPLA2-X, -IIA, -IID, -V and -IIE, respectively). YM 26734 displays minimal activity at sPLA2-IIF and no activity at cytosolic PLA2, cyclooxygenase and lipoxygenase. YM 26734 is used to ameliorates local inflammatory responses in TPA-induced mouse ear edema. Synonyms: YM 26734; YM26734; YM-26734; 1,1'-[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis-1-dodecanone; 1-[3-dodecanoyl-2,4,6-trihydroxy-5-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]phenyl]dodecan-1-one. Grades: ≥95% by HPLC. CAS No. 144337-18-8. Molecular formula: C45H62O8. Mole weight: 730.97. | |
| YM 26734 | YM 26734. Group: Biochemicals. Grades: Purified. CAS No. 144337-18-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| YM 298198 dihydrochloride | YM 298198 dihydrochloride is a selective mGluR-1 antagonist. In vivo, YM 298198 exhibits an antinociceptive effect in hyperalgesic mice. Synonyms: YM 298198 dihydrochloride; YM298198 dihydrochloride; YM-298198 dihydrochloride; 6-Amino-N-cyclohexyl-N,3-dimethylthiazolo[3,2-a]benzoimidazole-2-carboxamide dihydrochloride. Grades: 99%. CAS No. 299901-50-1. Molecular formula: C18H22N4OS.2HCl. Mole weight: 415.38. | |
| YM 298198 hydrochloride | Cas No. 1216398-09-2. | |
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