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| Product | Description | |
|---|---|---|
| Anti-ZIC2 antibody produced in rabbit | affinity isolated antibody, ammonium sulfate suspension. Group: Fluorescence/luminescence spectroscopy. |  |
| Anti-Zip Kinase antibody produced in rabbit | affinity isolated antibody, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-ZMAT3 antibody produced in rabbit | affinity isolated antibody. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-ZNF746 antibody produced in rabbit | ~1.0 mg/mL, affinity isolated antibody. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-ZNF746 (C-terminal region) antibody produced in rabbit | ~1.0 mg/mL, affinity isolated antibody. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-ZYX antibody produced in rabbit | affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Zyxin antibody, Mouse monoclonal | clone ZOL301, purified from hybridoma cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-Zyxin antibody produced in rabbit | IgG fraction of antiserum, buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| Ant-m7GDP | Ant-m7GDP is an exceptional pharmacological compound characterized by its profound capacity to combat viral infections. This awe-inspiring compound exhibits an unparalleled proclivity for selectively targeting and disrupting the intricate guanosine triphosphate cap structures, thereby impeding the vital process of viral mRNA capping. Synonyms: 2'/3'-O-Anthraniloyl-7-methylguanosine-5'-diphosphate, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C18H22N6O12P2 (free acid). Mole weight: 576.35 (free acid). |  |
| Ant-m7GMP | Ant-m7GMP is a biomedical compound used for the research of RNA-related diseases specifically targeting RNA molecules with the modified nucleotide 7-methylguanosine. By inhibiting the function of these modified RNA molecules, ant-m7GMP offers potential in studying conditions such as cancer, viral infections and neurological disorders. Synonyms: 2'/3'-O-Anthraniloyl-7-methylguanosine-5'-monophosphate, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C18H21N6O9P (free acid). Mole weight: 496.37 (free acid). | |
| Ant-m7GTP | Ant-m7GTP is a crucial tool used to study mRNA splicing and translation. It assists in investigating cellular processes and protein research. By targeting modified nucleotides in the mRNA cap structure is ant-m7GTP aids in understanding diseases like cancer and viral infections, enhancing drug discovery and development efforts. Synonyms: 2'/3'-O-Anthraniloyl-7-methylguanosine-5'-triphosphate, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C18H24N6O15P3 (free acid). Mole weight: 656.33 (free acid). | |
| Antofloxacin | Antofloxacin is an orally active and broad-spectrum 8-amino-fluoroquinolone with potent antibacterial activities. Antofloxacin shows superior antibacterial activity against gyrA mutation-positive H. pylori strains, especially in Asn87- mutated strains, compared to levofloxacin. Uses: Anti-bacterial agents. Synonyms: (S)-Antofloxacin; 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 8-amino-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, (3S)-. CAS No. 119354-43-7. Molecular formula: C18H21FN4O4. Mole weight: 376.38. | |
| Antofloxacin hydrochloride | Antofloxacin hydrochloride is a well tolerate, orally active and broad-spectrum 8-amino-fluoroquinolone antibiotic with potent antibacterial activities. Anthofloxacin hydrochloride is a weak, reversible CYP1A2 inhibitor for the treatment of various bacterial infections. It is also used to treat acute exacerbation of chronic bronchitis (AECB), acute pyelonephritis (AP), acute cystitis and multiple folliculitis. Uses: Anti-bacterial agents. Synonyms: (S)-Antofloxacin hydrochloride; (S)-8-amino-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride; 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid, 8-amino-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-, hydrochloride (1:1), (3S)-. Grade: ≥95%. CAS No. 873888-67-6. Molecular formula: C18H22ClFN4O4. Mole weight: 412.84. | |
| Antrafenine dihydrochloride | Antrafenine dihydrochloride. Group: Biochemicals. Alternative Names: 2- [ [7- (Trifluoromethyl) -4-quinolinyl] amino] benzoic acid [4-[3- (trifluoromethyl) phenyl]-1-piperazinyl]ethyl ester hydrochloride. Grades: Highly Purified. CAS No. 55300-30-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C30H28Cl2F6N4O2. US Biological Life Sciences. |  Worldwide |
| Antrafenine Dihydrochloride | Antrafenine Dihydrochloride is the dihydrochloride form of Antrafenine, which is a piperazine derivative drug. It acts as an analgesic and anti-inflammatory drug, but is not widely used. Uses: Antrafenine dihydrochloride acts as an analgesic and anti-inflammatory drug. Synonyms: 2-[[7-(TrifluoroMethyl)-4-quinolinyl]amino]benzoic Acid [4-[3-(TrifluoroMethyl)phenyl]-1-piperazinyl]ethyl Ester dihydrochloride; Benzoic acid, 2-((7-(trifluoromethyl)-4-quinolinyl)amino)-, 2-(4-(3-(trifluoromethyl)phenyl)-1-piperazinyl)ethyl ester, dihydrochloride. Grade: 98%. CAS No. 55300-30-6. Molecular formula: C30H28Cl2F6N4O2. Mole weight: 661.47. | |
| Antrimycin A | Antrimycin is a peptide antibiotic produced by Streptomyces xanthocidicus MG125-CF1. Antrimycin A has anti-Mycobamrimn smegmatis (Mycobamrimn smegmatis) and human Mycobacterium tuberculosis H37 Rv activity, and also has an effect on rifampicin and capreomycin-resistant bacteria. Synonyms: Antrimycin; Cirratiomycin B; L-Serine, 2-(hydroxymethyl)seryl-L-alanyl-L-erythro-alpha,beta-diaminobutyryl-L-2,3,4,5-tetrahydro-3-pyridazinecarbonyl-L-alanyl-(E)-2,3-didehydroisoleucyl-. Grade: >98%. CAS No. 80801-26-9. Molecular formula: C28H47N9O11. Mole weight: 685.72. | |
| Antrimycin B | Antrimycin is a peptide antibiotic produced by Streptomyces xanthocidicus MG125-CF1. Synonyms: 2-(Hydroxymethyl)-Ser-L-Ala-[(3S)-3-amino-L-Abu-]-1,6-didehydro-L-Pyz-L-Abu-2,3-didehydro-L-Ile-L-Ser-OH. CAS No. 82518-60-3. Molecular formula: C29H49N9O11. Mole weight: 699.75. | |
| Antrimycin C | Antrimycin is a peptide antibiotic produced by Streptomyces xanthocidicus MG125-CF1. CAS No. 82534-66-5. Molecular formula: C30H51N9O11. Mole weight: 713.78. | |
| Antroquinonol | Antroquinonol ((+)-Antroquinonol), a ubiquinone derivative from the mushroom Antrodia camphorata , has hepatoprotective, anti-inflammatory, and anti-cancer effects [1]. Antroquinonol can be used for the research of colon cancer [2]. Antroquinonol reduces oxidative stress by enhancing the Nrf2 signaling pathway and inhibits inflammation and sclerosis in focal segmental glomerulosclerosis mice [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (+)-Antroquinonol. CAS No. 1010081-09-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-19893. |  |
| ANTS | ANTS is a fluorescent dye. ANTS and DPX are encapsulated in liposomes can be an effective approach for measuring membrane leakage [1]. Uses: Scientific research. Group: Fluorescent dye. CAS No. 5398-34-5. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-D0789. | |
| Anwuligan | Anwuligan. Group: Biochemicals. Alternative Names: Macelignan; Calophyn. Grades: Plant Grade. CAS No. 107534-93-0. Pack Sizes: 20mg. Molecular Formula: C20H24O4, Molecular Weight: 328.402. US Biological Life Sciences. | Worldwide |
| ANX-510 | ANX-510 is a folate-based biomodulator with potential antineoplastic activity. 5,10-methylenetetrahydrofolate (MTHF) stabilizes the covalent binding of the fluorouracil metabolite 5-5-fluoro-2'-deoxyuridine-5'-O-monophosphate (FdUMP) to its target enzyme, thymidylate synthase, which results in inhibition of thymidylate synthase, depletion of thymidine triphosphate (TTP), a necessary constituent of DNA, and tumor cell death. Synonyms: 5,10-Methylenetetrahydrofolic acid; 5,10-Methylene-tetrahydrofolate; Tetrahydromethylenefolate; N-{4-[3-amino-1-oxo-1,2,5,6,6a,7-hexahydroimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl}-L-glutamic acid. CAS No. 3432-99-3. Molecular formula: C20H23N7O6. Mole weight: 457.44. | |
| Anziaic acid | It is produced by the strain of Stereocaulon ramulosum. Synonyms: NSC 766393; 6-Hydroxy-4-[(2,4-dihydroxy-6-pentylbenzoyl)oxy]-2-pentylbenzoic acid; 2,4-Dihydroxy-6-pentylbenzoic acid 4-carboxy-3-hydroxy-5-pentylphenyl ester; 4-(2,4-Dihydroxy-6-pentylbenzoyloxy)-6-pentylsalicylic acid; Benzoic acid, 2,4-dihydroxy-6-pentyl-, 4-carboxy-3-hydroxy-5-pentylphenyl ester; 4-Carboxy-3-hydroxy-5-pentylphenyl 2,4-dihydroxy-6-pentylbenzoate; Anzic acid. Grade: ≥98% by HPLC. CAS No. 641-68-9. Molecular formula: C24H30O7. Mole weight: 430.49. | |
| Anzurstobart | Anzurstobart (CC-95251; BMS-986351) is a high-affinity, fully human monoclonal anti-SIRP? antibody that blocks the binding of CD47 to SIRP?. Anzurstobart enhances macrophage phagocytic activity against DLBCL cell lines in co-culture models when combined with the antibody Rituximab (HY-P9913). Anzurstobart has the potential for solid and hematologic malignancies research[1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: CC-95251; BMS-986351. CAS No. 2543693-10-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990033. | |
| AOH1160 | AOH1160 is a first-in-class, potent and orally available inhibitor of PCNA, which plays an essential role in regulating DNA synthesis and repair and is indispensable to cancer cell growth and survival. AOH1160 selectively kills many types of cancer cells at below micromolar concentrations without causing significant toxicity to a broad range of nonmalignant cells. Synonyms: N-(2-Oxo-2-(2-phenoxyphenylamino)ethyl)-1-naphthamide. Grade: 99%. CAS No. 2089314-57-6. Molecular formula: C25H20N2O3. Mole weight: 396.44. | |
| AOH1160 | AOH1160 is a potent oral small molecule proliferating cell nuclear antigen (PCNA) inhibitor that interferes with DNA replication, blocks homologous recombination-mediated DNA repair, leads to cell cycle arrest and induces apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2089314-57-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120836. | |
| AOH1160-1LE | AOH1160-1LE is a derivative of AOH1160, a small-molecule PCNA inhibitor. AOH1160-1LE was shown to bind into the PCNA-interacting protein-box (PIP-box). Molecular formula: C28H24N2O5. Mole weight: 468.50. | |
| AOH1996 | AOH1996 is a small-molecule PCNA inhibitor that enhances the interaction between PCNA and the largest subunit of RNA polymerase II, RPB1, and dissociates PCNA from actively transcribed chromatin regions, while inducing DNA double-stranded breaks in a transcription-dependent manner. AOH1996 was identified as a selective chemotherapeutic. Synonyms: AOH 1996; AOH-1996; NSC789796; NSC-789796. Grade: 98%. CAS No. 2089314-64-5. Molecular formula: C26H22N2O4. Mole weight: 426.46. | |
| AOH1996-1LE | AOH1996-1LE is a derivative of AOH1160, a small-molecule PCNA inhibitor. AOH1996-1LE was shown to bind into the PCNA-interacting protein-box (PIP-box). | |
| AOP | AOP. Group: Biochemicals. Alternative Names: 7-(Azabenzotriazol-1-yl)oxy tris (dimethylamino) phosphonium hexafluorophosphate. Grades: Highly Purified. CAS No. 156311-85-2. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C11H21F6N7OP2. US Biological Life Sciences. | Worldwide |
| Aorta, Bovine | Aorta, Bovine. Group: Biologicals. Grades: Tissue. Pack Sizes: 10Ea. US Biological Life Sciences. | Worldwide |
| Aorta, Rabbit | Aorta, Rabbit. Group: Biologicals. Grades: Tissue. Pack Sizes: 50Ea. US Biological Life Sciences. | Worldwide |
| Aortic Artery Endothelial Cells, Human (Frozen) | Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement, is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| Aortic Artery Endothelial Cells, Human (T-25 flask) | Passage 3 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement, is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. | Worldwide |
| AOZ | analytical standard. Group: Application areas. | |
| AOZ-d4 | analytical standard. Group: Application areas. | |
| AOZ-[d4] | AOZ-[d4] is the labelled analogue of AOZ, which is a metabolite of Furazolidone. Synonyms: AOZ-d4; 3-Amino-2-oxazolidinone-d4; 3-Amino-1,3-oxazolidin-2-one-d4; NSC 111187-d4; NSC 196570-d4; NSC 38250-d4; Vetranal-d4. Grade: ≥97%; ≥97% atom D. CAS No. 1188331-23-8. Molecular formula: C3H2D4N2O2. Mole weight: 106.12. | |
| AP 1189 | AP 1189 exhibits biased agonistic activity towards the melanocortin 1 and melanocortin 3 receptors. Synonyms: Hydrazinecarboximidamide, 2-[(2E)-3-[1-(2-nitrophenyl)-1H-pyrrol-2-yl]-2-propen-1-ylidene]-, acetate (1:1), (2E)-; AP1189; AP-1189; Resomelagon acetate; (E)-2-((E)-3-(1-(2-nitrophenyl)-1H-pyrrol-2-yl)allylidene)hydrazine-1-carboximidamide acetate. Grade: ≥95%. CAS No. 1809420-72-1. Molecular formula: C14H14N6O2.C2H4O2. Mole weight: 358.35. | |
| AP1189 acetate | AP1189 is a biased agonist at receptors MC1 and MC3. AP1189 reduced cytokine release, an effect reliant on both MC1 and MC3 as evident from the use of Mc1r(-/-) and Mc3r(-/-) macrophages. No melanogenesis was induced by AP1189 in B16-F10 melanocytes. In vivo, oral AP1189 elicited anti-inflammatory actions in peritonitis and, upon administration at the peak of inflammation, accelerated the resolution phase by ~3-fold. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AP-1189; AP 1189; AP1189; AP1189 acetate. Product Category: Agonists. Appearance: Solid powder. CAS No. 959850-74-9. Molecular formula: C16H18N6O4. Mole weight: 358.36. Purity: >98%. IUPACName: (E)-N-[trans-3-{1-(2-Nitrophenyl)-1H-pyrrol-2-yl} allylidenamino]guanidinium acetate. Canonical SMILES: NC(N/N=C/C=C/C1=CC=CN1C2=CC=CC=C2[N+]([O-])=O)=N.CC(O)=O. Product ID: ACM959850749. Alfa Chemistry ISO 9001:2015 Certified. Categories: Resomelagon acetate. |  |
| AP14145 hydrochloride | AP14145 hydrochloride is a potent KCa2 (SK) channel negative allosteric modulator with an IC50 of 1.1 μM for KCa2.2 (SK2) and KCa2.3 (SK3) channels. CAS No. 2387505-59-9. Molecular formula: C18H18ClF3N4O. Mole weight: 398.81. | |
| AP14145 hydrochloride | AP14145 hydrochloride is a potent K Ca 2 (SK) channel negative allosteric modulator with an IC 50 of 1.1 μM for K Ca 2.2 (SK2) and K Ca 2.3 (SK3) channels. AP14145 hydrochloride inhibition strongly depends on two amino acids, S508 and A533 in the channel. AP14145 hydrochloride prolonged atrial effective refractory period (AERP) in rats and demonstrates antiarrhythmic effects in a Vernakalant-resistant porcine model of atrial fibrillation (AF) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2387505-59-9. Pack Sizes: 5 mg. Product ID: HY-120355A. | |
| AP18 | AP18 is a selective Transient receptor potential A1(TRPA1) channel blocker which reversibly inhibits TRPA1 with IC50 values of 3.1 and 4.5 μM at human and mouse respectively. It has been used to study TRPA1 signaling in mice and rats as well as in vitro. It blocks the transient receptor potential ankyrin 1 receptors and can reduce chronic pain associated with arthritis. It also blocks cinnamaldehyde-induced nociception in vivo and blocks cold- and mustard oil-induced activation of mouse TRPA1 but not capsaicin-induced activation. It reverses CFA-induced mechanical hyperalgesia in mice. Uses: Ap18 blocks the transient receptor potential ankyrin 1 receptors and can reduce chronic pain associated with arthritis. Synonyms: AP-18; AP 18; AP18. 4-(4-Chlorophenyl)-3-methylbut-3-en-2-oxime; AP-18; 4-(4-Chlorophenyl)-3-methyl-3-buten-2-oneoxime; (NE)-N-[(Z)-4-(4-chlorophenyl)-3-methylbut-3-en-2-ylidene]hydroxylamine; (2E,3E)-4-(4-chlorophenyl)-3-methylbut-3-en-2-one oxime. Grade: 98%. CAS No. 55224-94-7. Molecular formula: C11H12ClNO. Mole weight: 209.67. | |
| AP 18 | AP 18. Group: Biochemicals. Grades: Purified. CAS No. 55224-94-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AP-18 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| AP-18 | AP-18. Group: Biochemicals. Alternative Names: 4-(4-Chlorophenyl)-3-methyl-3-buten-2-one Oxime. Grades: Highly Purified. CAS No. 55224-94-7. Pack Sizes: 5mg. Molecular Formula: C11H12ClNO, Molecular Weight: 209.67. US Biological Life Sciences. | Worldwide |
| AP1867 | AP1867 is a synthetic FKBP12F36V-directed ligand[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 195514-23-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114434. | |
| AP1867-2-(carboxymethoxy) | AP1867-2-(carboxymethoxy), the AP1867 (a synthetic FKBP12F36V-directed ligand) based moiety, binds to CRBN ligand via a linker to form dTAG molecules. It is a ligand and a binder that contributes to the enhancer-promoter structural interactions of DNA elements. Synonyms: PROTAC FKBP12-binding moiety 2; 2-(2-((R)-3-(3,4-Dimethoxyphenyl)-1-(((S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carbonyl)oxy)propyl)phenoxy)acetic acid; 2-Piperidinecarboxylic acid, 1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-, (1R)-1-[2-(carboxymethoxy)phenyl]-3-(3,4-dimethoxyphenyl)propyl ester, (2S)-; Ortho-AP1867. Grade: ≥96%. CAS No. 2230613-03-1. Molecular formula: C38H47NO11. Mole weight: 693.78. | |
| AP1903 | AP1903 is a lipid-permeable tacrolimus analogue with homodimerizing activity. Dimerizer drug AP1903 homodimerizes an analogue of human protein FKBP12 (Fv) which contains a single acid substitution (Phe36Val) so that AP1903 binds to wild-type FKBP12 with 1000-fold lower affinity. Synonyms: AP1903; AP 1903; AP-1903; Rimiducid. Grade: 0.98. CAS No. 195514-63-7. Molecular formula: C78H98N4O20. Mole weight: 1411.63. | |
| AP-1/NF-κB activation inhibitor 1 | AP-1/NF-κB activation inhibitor 1 is a potent AP-1 and NF-κB mediated transcriptional activation inhibitor with an IC50 of 1 μM. AP-1/NF-κB activation inhibitor 1 has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells. Synonyms: AP-1/NF-kappaB activation inhibitor 1; 2-(Trifluoromethyl)-4-(2,5-dioxo-3-methyl-3-pyrroline-1-ylamino)pyrimidine-5-carboxylic acid ethyl ester. Grade: 99%. CAS No. 188936-12-1. Molecular formula: C13H11F3N4O4. Mole weight: 344.25. | |
| AP20187 | Systemic AP20187 administration results in time-dependent LFv2IRE tyrosine phosphorylation and activation of the insulin signaling pathway in both liver and muscle of AAV-treated NOD mice. AP20187 stimulation significantly increases hepatic glycogen content and muscular glucose uptake similarly to insulin. The homodimerizer has been widely used to study signal transduction pathways (by inducing oligomerization of cell surface receptor proteins), but it can be used to induce the activity/re-localization of any protein that is affected by oligomerization. To test the role of homodimerization in kinase activation, we constructed a fusion protein consisting of the SLK catalytic domain (amino acids 1-373) and a modified FK506 binding protein, Fv (Fv-SLK 1-373). Addition of AP20187 (an analog of FK506) enhanced the homodimerization of Fv-SLK 1-373. Synonyms: AP 20187; AP-20187. Grade: >98%. CAS No. 195514-80-8. Molecular formula: C82H107N5O20. Mole weight: 1482.75. | |
| AP20187 | AP20187 (B/B Homodimerizer) is a cell-permeable ligand used to dimerize FK506-binding protein (FKBP) fusion proteins and initiate biological signaling cascades and gene expression or disrupt protein-protein interactions. Uses: Scientific research. Group: Signaling pathways. Alternative Names: B/B Homodimerizer. CAS No. 195514-80-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13992. | |
| AP219 | AP219 is a control compound for AP39, which contains the triphenylphosphonium scaffold but lacking the H2 S-releasing portion. AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. Synonyms: (9-Carboxynonyl)triphenylphosphonium; 779282-36-9; AP219; 9-carboxynonyl(triphenyl)phosphanium; (9-Carboxynonyl)triphenyl-phosphonium; CHEMBL3582497; SCHEMBL20859564; AKOS040755143; (9-Carboxynonyl)triphenyl-phosphonium Bromide (>90%). Grade: ≥98%. CAS No. 779282-36-9. Molecular formula: C28H34O2P. Mole weight: 433.6. | |
| AP-22161 | AP-2216, designed to bind selectively to the Src SH2 domain by targeting a cysteine residue, has the potential to be further developed for treating osteoporosis. Synonyms: 4-[(2S)-2-acetamido-3-[[(5S)-3-carbamoyl-2-(cyclohexylmethoxy)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl]amino]-3-oxopropyl]-2-formylbenzoic acid; AP-22161; AP 22161; AP22161; SCHEMBL7243003; G7VE62573J; UNII-G7VE62573J. Grade: >98%. CAS No. 268741-42-0. Molecular formula: C32H39N3O7. Mole weight: 577.67. | |
| AP2238 | AP2238 is a inhibitor of both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. Uses: Cholinesterase inhibitors. Synonyms: AP-2238; AP 2238; AP2238; CHEMBL75121; UNII-545225E0BC; BDBM10949; DNC007569; 2H-1-Benzopyran-2-one, 6,7-dimethoxy-3-(4-((methyl(phenylmethyl)amino)methyl)phenyl)-; 3-[4-(N-Benzyl-N-methylaminomethyl)phenyl]-6,7-dimethoxy-2H-1-benzopyran-2-one. Grade: 98%. CAS No. 553681-56-4. Molecular formula: C26H25NO4. Mole weight: 415.48. | |
| AP-22408 | AP-22408, a Src tyrosine kinase inhibitor, is an orally bioavailable phosphotyrosine mimic resulting from a structurebased design. Synonyms: [4-[(2S)-2-acetamido-3-[[(5S)-3-carbamoyl-2-(cyclohexylmethoxy)-6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-yl]amino]-3-oxopropyl]-2-phosphonophenyl]phosphonic acid; AP-22408; AP 22408; AP22408; UNII-3U3L5QR4KV; CC1; AC1L9I7C; 3U3L5QR4KV; SCHEMBL7245569. Grade: >98%. CAS No. 268741-43-1. Molecular formula: C30H41N3O10P2. Mole weight: 665.61. | |
| AP23464 | AP23464 is a potent adenosine 5'-triphosphate (ATP)-based inhibitor of Src and Abl kinases. It displays antiproliferative activity against a human CML cell line and Bcr-Abl-transduced Ba/F3 cells with an IC50=14 nM. Synonyms: AP-23464; AP 23464; (4-((2-cyclopentyl-9-(3-hydroxyphenethyl)-9H-purin-6-yl)amino)phenyl)dimethylphosphine oxide. Grade: >98%. CAS No. 845895-51-4. Molecular formula: C30H38N5O2P. Mole weight: 475.53. | |
| AP23846 | AP23846 is a potent c-Src kinase inhibitor (IC50 approximately 0.5 nmol/L in vitro, approximately 10-fold more potent than PP2, the most widely used commercially available Src family kinase inhibitor). Synonyms: AP-23846; (4-((2-cyclopentyl-9-ethyl-9H-purin-6-yl)amino)phenyl)dipropylphosphine oxide. Grade: >98%. CAS No. 878654-51-4. Molecular formula: C20H16FN3O2. Mole weight: 439.53. | |
| AP23848 | AP23848 is a potent Bcr-Abl inhibitor. Synonyms: AP-23848; AP 23848; PF-562771; (4-((2-Cyclopentyl-9-(3-hydroxyphenethyl)-9H-purin-6-yl)amino)phenyl)dipropylphosphine oxide. Grade: >98%. CAS No. 834894-21-2. Molecular formula: C13H15N5O6. Mole weight: 531.63. | |
| AP 24534 | AP 24534. Group: Biochemicals. Grades: Purified. CAS No. 943319-70-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AP-24600 | AP-24600 is a bio-active chemical, but no detailed information has been published yet. Synonyms: AP-24600; AP 24600; AP24600; DA-12847; KB-310048; DA 12847; KB 310048; DA12847; KB310048; UNII-OZ477A282R; OZ477A282R; 3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylbenzoic acid. Grade: 98%. CAS No. 1300690-48-5. Molecular formula: C16H11N3O2. Mole weight: 277.28. | |
| AP 26113 | AP 26113. Group: Biochemicals. Grades: Highly Purified. CAS No. 1350848-43-9. Pack Sizes: 1mg. Molecular Formula: C26H34ClN6O2P, Molecular Weight: 529.01. US Biological Life Sciences. | Worldwide |
| AP-26113 | AP26113 is an orally available inhibitor of receptor tyrosine kinases anaplastic lymphoma kinase (ALK) and the epidermal growth factor receptor (EGFR) with potential antineoplastic activity. AP26113 binds to and inhibits ALK kinase and ALK fusion proteins as well as EGFR and mutant forms. AP26113 appears to overcome mutation-based resistance. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development. Synonyms: AP-26113; AP 26113; AP26113; (2-((5-chloro-2-((4-(4-(dimethylamino)piperidin-1-yl)-2-methoxyphenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide; AP26113-analog; AP-26113-analog; AP 26113-analog, Brigatinib-analog. Grade: 0.98. CAS No. 1197958-12-5. Molecular formula: C26H34ClN6O2P. Mole weight: 529.01. | |
| AP2A | AP2A, a prized medication within the biomedical industry, has transcended the boundaries of healing, showcasing its versatility in treating numerous afflictions, including but not limited to, managing pain, alleviating inflammatory disorders, and thwarting cancer. Prized for its utmost efficacy, AP2A efficaciously binds and regulates the activity of specific enzymatic and protein molecules that initiate the cascade of these aforementioned conditions. With its potential for therapeutic use being exhaustively studied and researched, it stands as an invaluable asset in the biomedicine realm. Synonyms: P1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 85065-24-3. Molecular formula: C20H26N10O13P2 (free acid). Mole weight: 676.43 (free acid). | |
| AP2Ribavirin | AP2Ribavirin, an antiviral drug, exerts its efficacy against the Hepatitis C virus (HCV) by curbing the replication of viral RNA through interference with RNA-dependent RNA polymerase. Coupled with other HCV drugs, AP2Ribavirin enhances therapeutic outcomes - serving as a frontline defense against this viral infection. Synonyms: 1,2,4-Triazole-3-carboxamide adenine dinucleotide, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C18H25N9O14P2 (free acid). Mole weight: 653.39 (free acid). | |
| AP30663 | AP30663 is a KCa2 channel inhibitor that can be used for the study of atrial fibrillation[1]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157557. | |
| AP39 | AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. It is also used as a photosensitizer, hydrogen sulfide donor, thioredoxin inhibitor or nitroxide combination use in photodynamic therapy. It consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. It stimulates mitochondrial electron transport and improves cellular bioenergetic function at lower concentrations (30-100 nM), while having an inhibitory effect at 300 nM. Grade: ≥95%. CAS No. 1429173-57-8. Molecular formula: C37H38O2PS3. Mole weight: 641.9. | |
| AP39 | AP39 is a triphenylphosphonium derivatised anethole dithiolethione and mitochondria-targeting hydrogen sulfide (H2S) donor. AP39 increases intracellular H2S levels. AP39 exerts cytoprotective effects and maintains mitochondrial DNA integrity under oxidative stress conditions. AP39 protects against myocardial reperfusion injury in mice model and has the potential for Alzheimer's disease research[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1429061-80-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126124. | |
| AP3A - lyophilized | AP3A - lyophilized is a biomedical product that holds immense value in understanding the complex aspects of liver-specific gene expression alongside the role of essential extracellular ATP. It has a proven track record in liver disease research and liver cancer. AP3A's profound potency lies in activating P2Y purinergic receptors, thus leading to a significant surge in ATP stimulation within liver cells. AP3A's ever-efficient lyophilized form guarantees long-term storage and easy usability for laboratory experiments. Synonyms: (ApppA); P1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 5959-90-0. Molecular formula: C20H27N10O16P3 (free acid). Mole weight: 756.41 (free acid). | |
| AP3A - solution | AP3A solution, a biochemical product entrenched in biomedical industry, commands center stage in studying purinergic signaling pathways, amongst others. This efficacious prodigy, a mainstay in academic research labs, abets multifarious research endeavors including, but not limited to, curing autoimmune disorders, neurodegenerative diseases, and cancer. AP3A solution, sourced from different research chemical providers, beckons an important armamentarium for scientists and researchers aiming to unearth the intricacies of cellular signaling pathways. Synonyms: (ApppA); P1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C20H27N10O16P3 (free acid). Mole weight: 756.41 (free acid). | |
| AP3G (A cap) | AP3G (A cap) is a non-functional cap analog used in the synthesis of mRNA to estimate the level of cap-independent translation. Synonyms: (ApppG); P1-(5'-Adenosyl) P3-(5'-guanosyl) triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C20H27N10O17P3 (free acid). Mole weight: 772.41 (free acid). | |
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